Planaria EST Database

DrC_00591

BLASTX 2.2.13 [Nov-27-2005]

Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= DrC_00591
         (1065 letters)

Database: Non-redundant SwissProt sequences 
           184,735 sequences; 68,354,980 total letters



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

sp|O60911|CATL2_HUMAN  Cathepsin L2 precursor (Cathepsin V) ...   334   3e-91
sp|Q9GL24|CATL_CANFA  Cathepsin L precursor [Contains: Cathe...   332   1e-90
sp|P07711|CATL_HUMAN  Cathepsin L precursor (Major excreted ...   329   9e-90
sp|P25975|CATL_BOVIN  Cathepsin L precursor [Contains: Cathe...   324   2e-88
sp|Q26636|CATL_SARPE  Cathepsin L precursor [Contains: Cathe...   321   2e-87
sp|Q28944|CATL_PIG  Cathepsin L precursor [Contains: Catheps...   321   3e-87
sp|P25782|CYSP2_HOMAM  Digestive cysteine proteinase 2 precu...   317   5e-86
sp|P07154|CATL_RAT  Cathepsin L precursor (Major excreted pr...   315   1e-85
sp|Q24940|CATLP_FASHE  Cathepsin L-like proteinase precursor      315   1e-85
sp|P06797|CATL_MOUSE  Cathepsin L precursor (Major excreted ...   315   2e-85

>sp|O60911|CATL2_HUMAN Cathepsin L2 precursor (Cathepsin V) (Cathepsin U)
          Length = 334

 Score =  334 bits (856), Expect = 3e-91
 Identities = 169/334 (50%), Positives = 214/334 (64%), Gaps = 5/334 (1%)
 Frame = +1

Query: 10  LILSLVVVAITAVPQKFSVNSELNEEWETYKTTFGRKYDELTDITRRLIWEQNLKYIQKH 189
           L+L+   + I +   KF  N  L+ +W  +K T  R Y    +  RR +WE+N+K I+ H
Sbjct: 5   LVLAAFCLGIASAVPKFDQN--LDTKWYQWKATHRRLYGANEEGWRRAVWEKNMKMIELH 62

Query: 190 NLEYDLGKHTYSLGLNQFADMTNEEFKAKYLGIMKTKPTLEGSTYMAPENIGVLPASVDW 369
           N EY  GKH +++ +N F DMTNEEF+ + +G  + +   +G  +  P  +  LP SVDW
Sbjct: 63  NGEYSQGKHGFTMAMNAFGDMTNEEFR-QMMGCFRNQKFRKGKVFREPLFLD-LPKSVDW 120

Query: 370 RQKGYVTPVKNQQQCGSCWSFSATGSLEGQYFRKNNRLISFSEQQLVDCSXXXXXXXXXX 549
           R+KGYVTPVKNQ+QCGSCW+FSATG+LEGQ FRK  +L+S SEQ LVDCS          
Sbjct: 121 RKKGYVTPVKNQKQCGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSRPQGNQGCNG 180

Query: 550 XLMDNAFRYIKDQ-GIESEGDYPYTATDGTCKRNPSKIVTKCTGFTDIQSQNETDLANAV 726
             M  AF+Y+K+  G++SE  YPY A D  CK  P   V   TGFT +    E  L  AV
Sbjct: 181 GFMARAFQYVKENGGLDSEESYPYVAVDEICKYRPENSVANDTGFTVVAPGKEKALMKAV 240

Query: 727 ATVGPVSVAIDAGHASFQLYKSGIYNEESCSTTQLDHGVLAVGYG----TQIGKKYWIVK 894
           ATVGP+SVA+DAGH+SFQ YKSGIY E  CS+  LDHGVL VGYG         KYW+VK
Sbjct: 241 ATVGPISVAMDAGHSSFQFYKSGIYFEPDCSSKNLDHGVLVVGYGFEGANSNNSKYWLVK 300

Query: 895 NSWDVTWGESGYIKMSKDKKNQCGIATMASYPLV 996
           NSW   WG +GY+K++KDK N CGIAT ASYP V
Sbjct: 301 NSWGPEWGSNGYVKIAKDKNNHCGIATAASYPNV 334

>sp|Q9GL24|CATL_CANFA Cathepsin L precursor [Contains: Cathepsin L heavy chain; Cathepsin
           L light chain]
          Length = 333

 Score =  332 bits (851), Expect = 1e-90
 Identities = 173/334 (51%), Positives = 211/334 (63%), Gaps = 5/334 (1%)
 Frame = +1

Query: 10  LILSLVVVAITAVPQKFSVNSELNEEWETYKTTFGRKYDELTDITRRLIWEQNLKYIQKH 189
           L L+ + + I +   KF  +  LN +W  +K T  R Y    +  RR +WE+N+K I+ H
Sbjct: 5   LFLTALCLGIASAAPKF--DQSLNAQWYQWKATHRRLYGMNEEGWRRAVWEKNMKMIELH 62

Query: 190 NLEYDLGKHTYSLGLNQFADMTNEEFKAKYLGIMKTKPTLEGSTYMAPENIGVLPASVDW 369
           N EY  GKH +++ +N F DMTNEEF+    G    K   +G  +  P     +P SVDW
Sbjct: 63  NREYSQGKHGFTMAMNAFGDMTNEEFRQVMNGFQNQKHK-KGKMFQEPL-FAEIPKSVDW 120

Query: 370 RQKGYVTPVKNQQQCGSCWSFSATGSLEGQYFRKNNRLISFSEQQLVDCSXXXXXXXXXX 549
           R+KGYVTPVKNQ QCGSCW+FSATG+LEGQ FRK  +L+S SEQ LVDCS          
Sbjct: 121 REKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSRAQGNEGCNG 180

Query: 550 XLMDNAFRYIKDQ-GIESEGDYPYTATD-GTCKRNPSKIVTKCTGFTDIQSQNETDLANA 723
            LMDNAFRY+KD  G++SE  YPY   D  TC   P       TGF D+  Q E  L  A
Sbjct: 181 GLMDNAFRYVKDNGGLDSEESYPYLGRDTETCNYKPECSAANDTGFVDL-PQREKALMKA 239

Query: 724 VATVGPVSVAIDAGHASFQLYKSGIYNEESCSTTQLDHGVLAVGY---GTQIGKKYWIVK 894
           VAT+GP+SVAIDAGH SFQ YKSGIY +  CS+  LDHGVL VGY   GT    K+WIVK
Sbjct: 240 VATLGPISVAIDAGHQSFQFYKSGIYFDPDCSSKDLDHGVLVVGYGFEGTDSNNKFWIVK 299

Query: 895 NSWDVTWGESGYIKMSKDKKNQCGIATMASYPLV 996
           NSW   WG +GY+KM+KD+ N CGIAT ASYP V
Sbjct: 300 NSWGPEWGWNGYVKMAKDQNNHCGIATAASYPTV 333

>sp|P07711|CATL_HUMAN Cathepsin L precursor (Major excreted protein) (MEP) [Contains:
           Cathepsin L heavy chain; Cathepsin L light chain]
          Length = 333

 Score =  329 bits (843), Expect = 9e-90
 Identities = 171/334 (51%), Positives = 211/334 (63%), Gaps = 5/334 (1%)
 Frame = +1

Query: 10  LILSLVVVAITAVPQKFSVNSELNEEWETYKTTFGRKYDELTDITRRLIWEQNLKYIQKH 189
           LIL+   + I +    F  +  L  +W  +K    R Y    +  RR +WE+N+K I+ H
Sbjct: 5   LILAAFCLGIASATLTF--DHSLEAQWTKWKAMHNRLYGMNEEGWRRAVWEKNMKMIELH 62

Query: 190 NLEYDLGKHTYSLGLNQFADMTNEEFKAKYLGIMKTKPTLEGSTYMAPENIGVLPASVDW 369
           N EY  GKH++++ +N F DMT+EEF+    G    KP  +G  +  P      P SVDW
Sbjct: 63  NQEYREGKHSFTMAMNAFGDMTSEEFRQVMNGFQNRKPR-KGKVFQEPLFYEA-PRSVDW 120

Query: 370 RQKGYVTPVKNQQQCGSCWSFSATGSLEGQYFRKNNRLISFSEQQLVDCSXXXXXXXXXX 549
           R+KGYVTPVKNQ QCGSCW+FSATG+LEGQ FRK  RLIS SEQ LVDCS          
Sbjct: 121 REKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNG 180

Query: 550 XLMDNAFRYIKDQ-GIESEGDYPYTATDGTCKRNPSKIVTKCTGFTDIQSQNETDLANAV 726
            LMD AF+Y++D  G++SE  YPY AT+ +CK NP   V   TGF DI  Q E  L  AV
Sbjct: 181 GLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPKQ-EKALMKAV 239

Query: 727 ATVGPVSVAIDAGHASFQLYKSGIYNEESCSTTQLDHGVLAVGYGTQI----GKKYWIVK 894
           ATVGP+SVAIDAGH SF  YK GIY E  CS+  +DHGVL VGYG +       KYW+VK
Sbjct: 240 ATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVK 299

Query: 895 NSWDVTWGESGYIKMSKDKKNQCGIATMASYPLV 996
           NSW   WG  GY+KM+KD++N CGIA+ ASYP V
Sbjct: 300 NSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV 333

>sp|P25975|CATL_BOVIN Cathepsin L precursor [Contains: Cathepsin L heavy chain; Cathepsin
           L light chain]
          Length = 334

 Score =  324 bits (831), Expect = 2e-88
 Identities = 172/333 (51%), Positives = 207/333 (62%), Gaps = 6/333 (1%)
 Frame = +1

Query: 16  LSLVVVAITAVPQKFSVNSELNEEWETYKTTFGRKYDELTDITRRLIWEQNLKYIQKHNL 195
           L+++ + + +   K   N  L+  W  +K T  R Y    +  RR +WE+N K I  HN 
Sbjct: 7   LTVLCLGVASAAPKLDPN--LDAHWHQWKATHRRLYGMNEEEWRRAVWEKNKKIIDLHNQ 64

Query: 196 EYDLGKHTYSLGLNQFADMTNEEFKAKYLGIMKTKPTLEGSTYMAPENIGVLPASVDWRQ 375
           EY  GKH + + +N F DMTNEEF+    G    K   +G  +  P  + V P SVDW +
Sbjct: 65  EYSEGKHAFRMAMNAFGDMTNEEFRQVMNGFQNQKHK-KGKLFHEPLLVDV-PKSVDWTK 122

Query: 376 KGYVTPVKNQQQCGSCWSFSATGSLEGQYFRKNNRLISFSEQQLVDCSXXXXXXXXXXXL 555
           KGYVTPVKNQ QCGSCW+FSATG+LEGQ FRK  +L+S SEQ LVDCS           L
Sbjct: 123 KGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSRAQGNQGCNGGL 182

Query: 556 MDNAFRYIKDQ-GIESEGDYPYTATD-GTCKRNPSKIVTKCTGFTDIQSQNETDLANAVA 729
           MDNAF+YIKD  G++SE  YPY ATD  +C   P       TGF DI  Q E  L  AVA
Sbjct: 183 MDNAFQYIKDNGGLDSEESYPYLATDTNSCNYKPECSAANDTGFVDI-PQREKALMKAVA 241

Query: 730 TVGPVSVAIDAGHASFQLYKSGIYNEESCSTTQLDHGVLAVGYGTQ----IGKKYWIVKN 897
           TVGP+SVAIDAGH SFQ YKSGIY +  CS   LDHGVL VGYG +       K+WIVKN
Sbjct: 242 TVGPISVAIDAGHTSFQFYKSGIYYDPDCSCKDLDHGVLVVGYGFEGTDSNNNKFWIVKN 301

Query: 898 SWDVTWGESGYIKMSKDKKNQCGIATMASYPLV 996
           SW   WG +GY+KM+KD+ N CGIAT ASYP V
Sbjct: 302 SWGPEWGWNGYVKMAKDQNNHCGIATAASYPTV 334

>sp|Q26636|CATL_SARPE Cathepsin L precursor [Contains: Cathepsin L heavy chain; Cathepsin L
            light chain]
          Length = 339

 Score =  321 bits (823), Expect = 2e-87
 Identities = 168/335 (50%), Positives = 214/335 (63%), Gaps = 10/335 (2%)
 Frame = +1

Query: 22   LVVVAITAVPQKFSVNSELNEEWETYKTTFGRKY-DELTDITRRLIWEQNLKYIQKHNLE 198
            + ++A+ A+ Q  S    + EEW TYK    + Y +E+ +  R  I+ +N   I KHN  
Sbjct: 6    VALLALVALTQAISPLDLIKEEWHTYKLQHRKNYANEVEERFRMKIFNENRHKIAKHNQL 65

Query: 199  YDLGKHTYSLGLNQFADMTNEEFKAKYLG-------IMKTKPTLEGSTYMAPENIGVLPA 357
            +  GK +Y LGLN++ADM + EFK    G       +M+ +  L G+TY+ P ++ V P 
Sbjct: 66   FAQGKVSYKLGLNKYADMLHHEFKETMNGYNHTLRQLMRERTGLVGATYIPPAHVTV-PK 124

Query: 358  SVDWRQKGYVTPVKNQQQCGSCWSFSATGSLEGQYFRKNNRLISFSEQQLVDCSXXXXXX 537
            SVDWR+ G VT VK+Q  CGSCW+FS+TG+LEGQ+FRK   L+S SEQ LVDCS      
Sbjct: 125  SVDWREHGAVTGVKDQGHCGSCWAFSSTGALEGQHFRKAGVLVSLSEQNLVDCSTKYGNN 184

Query: 538  XXXXXLMDNAFRYIKDQG-IESEGDYPYTATDGTCKRNPSKIVTKCTGFTDIQSQNETDL 714
                 LMDNAFRYIKD G I++E  YPY   D +C  N + I    TGF DI   +E  +
Sbjct: 185  GCNGGLMDNAFRYIKDNGGIDTEKSYPYEGIDDSCHFNKATIGATDTGFVDIPEGDEEKM 244

Query: 715  ANAVATVGPVSVAIDAGHASFQLYKSGIYNEESCSTTQLDHGVLAVGYGT-QIGKKYWIV 891
              AVAT+GPVSVAIDA H SFQLY  G+YNE  C    LDHGVL VGYGT + G  YW+V
Sbjct: 245  KKAVATMGPVSVAIDASHESFQLYSEGVYNEPECDEQNLDHGVLVVGYGTDESGMDYWLV 304

Query: 892  KNSWDVTWGESGYIKMSKDKKNQCGIATMASYPLV 996
            KNSW  TWGE GYIKM++++ NQCGIAT +SYP V
Sbjct: 305  KNSWGTTWGEQGYIKMARNQNNQCGIATASSYPTV 339

>sp|Q28944|CATL_PIG Cathepsin L precursor [Contains: Cathepsin L heavy chain; Cathepsin
           L light chain]
          Length = 334

 Score =  321 bits (822), Expect = 3e-87
 Identities = 169/335 (50%), Positives = 211/335 (62%), Gaps = 6/335 (1%)
 Frame = +1

Query: 10  LILSLVVVAITAVPQKFSVNSELNEEWETYKTTFGRKYDELTDITRRLIWEQNLKYIQKH 189
           L L+ + + I +   K   N  L+ +W  +K T GR Y    +  RR +WE+N+K I+ H
Sbjct: 5   LFLTALCLGIASAAPKLDQN--LDADWYKWKATHGRLYGMNEEGWRRAVWEKNMKMIELH 62

Query: 190 NLEYDLGKHTYSLGLNQFADMTNEEFKAKYLGIMKTKPTLEGSTYMAPENIGVLPASVDW 369
           N EY  GKH +S+ +N F DMTNEEF+    G    K   +G  +     + V P SVDW
Sbjct: 63  NQEYSQGKHGFSMAMNAFGDMTNEEFRQVMNGFQNQKHK-KGKVFHESLVLEV-PKSVDW 120

Query: 370 RQKGYVTPVKNQQQCGSCWSFSATGSLEGQYFRKNNRLISFSEQQLVDCSXXXXXXXXXX 549
           R+KGYVT VKNQ QCGSCW+FSATG+LEGQ FRK  +L+S SEQ LVDCS          
Sbjct: 121 REKGYVTAVKNQGQCGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSRPQGNQGCNG 180

Query: 550 XLMDNAFRYIKDQ-GIESEGDYPYTATD-GTCKRNPSKIVTKCTGFTDIQSQNETDLANA 723
            LMDNAF+Y+KD  G+++E  YPY   +  +C   P       TGF DI  Q E  L  A
Sbjct: 181 GLMDNAFQYVKDNGGLDTEESYPYLGRETNSCTYKPECSAANDTGFVDI-PQREKALMKA 239

Query: 724 VATVGPVSVAIDAGHASFQLYKSGIYNEESCSTTQLDHGVLAVGYGTQ----IGKKYWIV 891
           VATVGP+SVAIDAGH+SFQ YKSGIY +  CS+  LDHGVL VGYG +       K+WIV
Sbjct: 240 VATVGPISVAIDAGHSSFQFYKSGIYYDPDCSSKDLDHGVLVVGYGFEGTDSNSSKFWIV 299

Query: 892 KNSWDVTWGESGYIKMSKDKKNQCGIATMASYPLV 996
           KNSW   WG +GY+KM+KD+ N CGI+T ASYP V
Sbjct: 300 KNSWGPEWGWNGYVKMAKDQNNHCGISTAASYPTV 334

>sp|P25782|CYSP2_HOMAM Digestive cysteine proteinase 2 precursor
          Length = 323

 Score =  317 bits (811), Expect = 5e-86
 Identities = 156/305 (51%), Positives = 209/305 (68%), Gaps = 2/305 (0%)
 Frame = +1

Query: 88  WETYKTTFGRKY-DELTDITRRLIWEQNLKYIQKHNLEYDLGKHTYSLGLNQFADMTNEE 264
           WE +K  +GR+Y D   D  RR+I+EQN KYI++ N +Y+ G+ T++L +N+F DMT EE
Sbjct: 20  WEHFKGKYGRQYVDAEEDSYRRVIFEQNQKYIEEFNKKYENGEVTFNLAMNKFGDMTLEE 79

Query: 265 FKAKYLGIMKTKPTLEGSTYMAPENIGVLPASVDWRQKGYVTPVKNQQQCGSCWSFSATG 444
           F A   G +  + +   S +   +  G     VDWR KG VTPVK+Q QCGSCW+FS TG
Sbjct: 80  FNAVMKGNIPRR-SAPVSVFYPKKETGPQATEVDWRTKGAVTPVKDQGQCGSCWAFSTTG 138

Query: 445 SLEGQYFRKNNRLISFSEQQLVDCSXXXXXXXXXXXLMDNAFRYIK-DQGIESEGDYPYT 621
           SLEGQ+F K   LIS +EQQLVDCS            M++AF YIK + GI++E  YPY 
Sbjct: 139 SLEGQHFLKTGSLISLAEQQLVDCSRPYGPQGCNGGWMNDAFDYIKANNGIDTEAAYPYE 198

Query: 622 ATDGTCKRNPSKIVTKCTGFTDIQSQNETDLANAVATVGPVSVAIDAGHASFQLYKSGIY 801
           A DG+C+ + + +   C+G T+I S +ET L  AV  +GP+SV IDA H+SFQ Y SG+Y
Sbjct: 199 ARDGSCRFDSNSVAATCSGHTNIASGSETGLQQAVRDIGPISVTIDAAHSSFQFYSSGVY 258

Query: 802 NEESCSTTQLDHGVLAVGYGTQIGKKYWIVKNSWDVTWGESGYIKMSKDKKNQCGIATMA 981
            E SCS + LDH VLAVGYG++ G+ +W+VKNSW  +WG++GYIKMS+++ N CGIAT+A
Sbjct: 259 YEPSCSPSYLDHAVLAVGYGSEGGQDFWLVKNSWATSWGDAGYIKMSRNRNNNCGIATVA 318

Query: 982 SYPLV 996
           SYPLV
Sbjct: 319 SYPLV 323

>sp|P07154|CATL_RAT Cathepsin L precursor (Major excreted protein) (MEP) (Cyclic
           protein 2) (CP-2) [Contains: Cathepsin L heavy chain;
           Cathepsin L light chain]
          Length = 334

 Score =  315 bits (808), Expect = 1e-85
 Identities = 167/335 (49%), Positives = 211/335 (62%), Gaps = 5/335 (1%)
 Frame = +1

Query: 7   ILILSLVVVAITAVPQKFSVNSELNEEWETYKTTFGRKYDELTDITRRLIWEQNLKYIQK 186
           +L+L+++ +       KF  +   N +W  +K+T  R Y    +  RR +WE+N++ IQ 
Sbjct: 4   LLLLAVLCLGTALATPKF--DQTFNAQWHQWKSTHRRLYGTNEEEWRRAVWEKNMRMIQL 61

Query: 187 HNLEYDLGKHTYSLGLNQFADMTNEEFKAKYLGIMKTKPTLEGSTYMAPENIGVLPASVD 366
           HN EY  GKH +++ +N F DMTNEEF+    G    K   +G  +  P  + + P +VD
Sbjct: 62  HNGEYSNGKHGFTMEMNAFGDMTNEEFRQIVNGYRHQKHK-KGRLFQEPLMLQI-PKTVD 119

Query: 367 WRQKGYVTPVKNQQQCGSCWSFSATGSLEGQYFRKNNRLISFSEQQLVDCSXXXXXXXXX 546
           WR+KG VTPVKNQ QCGSCW+FSA+G LEGQ F K  +LIS SEQ LVDCS         
Sbjct: 120 WREKGCVTPVKNQGQCGSCWAFSASGCLEGQMFLKTGKLISLSEQNLVDCSHDQGNQGCN 179

Query: 547 XXLMDNAFRYIKDQ-GIESEGDYPYTATDGTCKRNPSKIVTKCTGFTDIQSQNETDLANA 723
             LMD AF+YIK+  G++SE  YPY A DG+CK      V   TGF DI  Q E  L  A
Sbjct: 180 GGLMDFAFQYIKENGGLDSEESYPYEAKDGSCKYRAEYAVANDTGFVDI-PQQEKALMKA 238

Query: 724 VATVGPVSVAIDAGHASFQLYKSGIYNEESCSTTQLDHGVLAVGY---GTQIGK-KYWIV 891
           VATVGP+SVA+DA H S Q Y SGIY E +CS+  LDHGVL VGY   GT   K KYW+V
Sbjct: 239 VATVGPISVAMDASHPSLQFYSSGIYYEPNCSSKDLDHGVLVVGYGYEGTDSNKDKYWLV 298

Query: 892 KNSWDVTWGESGYIKMSKDKKNQCGIATMASYPLV 996
           KNSW   WG  GYIK++KD+ N CG+AT ASYP+V
Sbjct: 299 KNSWGKEWGMDGYIKIAKDRNNHCGLATAASYPIV 333

>sp|Q24940|CATLP_FASHE Cathepsin L-like proteinase precursor
          Length = 326

 Score =  315 bits (807), Expect = 1e-85
 Identities = 153/327 (46%), Positives = 209/327 (63%)
 Frame = +1

Query: 16  LSLVVVAITAVPQKFSVNSELNEEWETYKTTFGRKYDELTDITRRLIWEQNLKYIQKHNL 195
           + L ++A+  V     V    ++ W  +K  + ++Y+   D  RR IWE+N+K+IQ+HNL
Sbjct: 1   MRLFILAVLTV----GVLGSNDDLWHQWKRMYNKEYNGADDQHRRNIWEKNVKHIQEHNL 56

Query: 196 EYDLGKHTYSLGLNQFADMTNEEFKAKYLGIMKTKPTLEGSTYMAPENIGVLPASVDWRQ 375
            +DLG  TY+LGLNQF DMT EEFKAKYL  M     +         N   +P  +DWR+
Sbjct: 57  RHDLGLVTYTLGLNQFTDMTFEEFKAKYLTEMSRASDILSHGVPYEANNRAVPDKIDWRE 116

Query: 376 KGYVTPVKNQQQCGSCWSFSATGSLEGQYFRKNNRLISFSEQQLVDCSXXXXXXXXXXXL 555
            GYVT VK+Q  CGSCW+FS TG++EGQY +     ISFSEQQLVDCS           L
Sbjct: 117 SGYVTEVKDQGNCGSCWAFSTTGTMEGQYMKNERTSISFSEQQLVDCSGPWGNNGCSGGL 176

Query: 556 MDNAFRYIKDQGIESEGDYPYTATDGTCKRNPSKIVTKCTGFTDIQSQNETDLANAVATV 735
           M+NA++Y+K  G+E+E  YPYTA +G C+ N    V K TG+  + S +E +L N V   
Sbjct: 177 MENAYQYLKQFGLETESSYPYTAVEGQCRYNKQLGVAKVTGYYTVHSGSEVELKNLVGAR 236

Query: 736 GPVSVAIDAGHASFQLYKSGIYNEESCSTTQLDHGVLAVGYGTQIGKKYWIVKNSWDVTW 915
            P +VA+D   + F +Y+SGIY  ++CS  +++H VLAVGYGTQ G  YWIVKNSW   W
Sbjct: 237 RPAAVAVDV-ESDFMMYRSGIYQSQTCSPLRVNHAVLAVGYGTQGGTDYWIVKNSWGTYW 295

Query: 916 GESGYIKMSKDKKNQCGIATMASYPLV 996
           GE GYI+M++++ N CGIA++AS P+V
Sbjct: 296 GERGYIRMARNRGNMCGIASLASLPMV 322

>sp|P06797|CATL_MOUSE Cathepsin L precursor (Major excreted protein) (MEP) (p39 cysteine
           proteinase) [Contains: Cathepsin L heavy chain;
           Cathepsin L light chain]
          Length = 334

 Score =  315 bits (806), Expect = 2e-85
 Identities = 169/335 (50%), Positives = 211/335 (62%), Gaps = 5/335 (1%)
 Frame = +1

Query: 7   ILILSLVVVAITAVPQKFSVNSELNEEWETYKTTFGRKYDELTDITRRLIWEQNLKYIQK 186
           +L+L+++ +       KF  +   + EW  +K+T  R Y    +  RR IWE+N++ IQ 
Sbjct: 4   LLLLAVLCLGTALATPKF--DQTFSAEWHQWKSTHRRLYGTNEEEWRRAIWEKNMRMIQL 61

Query: 187 HNLEYDLGKHTYSLGLNQFADMTNEEFKAKYLGIMKTKPTLEGSTYMAPENIGVLPASVD 366
           HN EY  G+H +S+ +N F DMTNEEF+    G    K   +G  +  P  + + P SVD
Sbjct: 62  HNGEYSNGQHGFSMEMNAFGDMTNEEFRQVVNGYRHQKHK-KGRLFQEPLMLKI-PKSVD 119

Query: 367 WRQKGYVTPVKNQQQCGSCWSFSATGSLEGQYFRKNNRLISFSEQQLVDCSXXXXXXXXX 546
           WR+KG VTPVKNQ QCGSCW+FSA+G LEGQ F K  +LIS SEQ LVDCS         
Sbjct: 120 WREKGCVTPVKNQGQCGSCWAFSASGCLEGQMFLKTGKLISLSEQNLVDCSHAQGNQGCN 179

Query: 547 XXLMDNAFRYIKDQ-GIESEGDYPYTATDGTCKRNPSKIVTKCTGFTDIQSQNETDLANA 723
             LMD AF+YIK+  G++SE  YPY A DG+CK      V   TGF DI  Q E  L  A
Sbjct: 180 GGLMDFAFQYIKENGGLDSEESYPYEAKDGSCKYRAEFAVANDTGFVDI-PQQEKALMKA 238

Query: 724 VATVGPVSVAIDAGHASFQLYKSGIYNEESCSTTQLDHGVLAVGY---GTQIGK-KYWIV 891
           VATVGP+SVA+DA H S Q Y SGIY E +CS+  LDHGVL VGY   GT   K KYW+V
Sbjct: 239 VATVGPISVAMDASHPSLQFYSSGIYYEPNCSSKNLDHGVLLVGYGYEGTDSNKNKYWLV 298

Query: 892 KNSWDVTWGESGYIKMSKDKKNQCGIATMASYPLV 996
           KNSW   WG  GYIK++KD+ N CG+AT ASYP+V
Sbjct: 299 KNSWGSEWGMEGYIKIAKDRDNHCGLATAASYPVV 333

  Database: Non-redundant SwissProt sequences
    Posted date:  Dec 6, 2005  7:40 AM
  Number of letters in database: 68,354,980
  Number of sequences in database:  184,735
  
  Database: swissprot.01
    Posted date:  Dec 6, 2005  8:18 AM
  Number of letters in database: 66,202,850
  Number of sequences in database:  184,431
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 117,723,769
Number of Sequences: 369166
Number of extensions: 2401935
Number of successful extensions: 7232
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 6373
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 6636
length of database: 68,354,980
effective HSP length: 112
effective length of database: 47,664,660
effective search space used: 11534847720
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)

Cluster detail

DrC_00591

  1. Dr_sW_024_N11
  2. Dr_sW_001_E14
  3. Dr_sW_010_M08
  4. Dr_sW_025_L05
  5. Dr_sW_021_I07
  6. Dr_sW_027_O08
  7. Dr_sW_028_K13
  8. Dr_sW_028_M17
  9. Dr_sW_012_B18
  10. Dr_sW_003_M09
  11. Dr_sW_025_P11
  12. Dr_sW_014_M21
  13. Dr_sW_012_A21
  14. Dr_sW_015_I20
  15. Dr_sW_002_B17
  16. Dr_sW_008_E06
  17. Dr_sW_003_J22
  18. Dr_sW_022_D22
  19. Dr_sW_022_B22
  20. Dr_sW_015_H08
  21. Dr_sW_013_I09
  22. Dr_sW_013_O13
  23. Dr_sW_001_C04
  24. Dr_sW_012_A01
  25. Dr_sW_015_A13
  26. Dr_sW_018_O13
  27. Dr_sW_006_H09
  28. Dr_sW_001_D01
  29. Dr_sW_013_D08
  30. Dr_sW_019_E06
  31. Dr_sW_019_B06
  32. Dr_sW_004_D06
  33. Dr_sW_007_C05
  34. Dr_sW_021_N08
  35. Dr_sW_024_H16
  36. Dr_sW_024_C18
  37. Dr_sW_019_O17
  38. Dr_sW_023_M07
  39. Dr_sW_011_E04
  40. Dr_sW_026_D04
  41. Dr_sW_019_D09
  42. Dr_sW_010_L10
  43. Dr_sW_018_K12
  44. Dr_sW_005_L16
  45. Dr_sW_020_O15
  46. Dr_sW_005_J01
  47. Dr_sW_013_J23
  48. Dr_sW_019_K14
  49. Dr_sW_015_L08
  50. Dr_sW_024_H07
  51. Dr_sW_001_A13
  52. Dr_sW_010_O11
  53. Dr_sW_011_G04
  54. Dr_sW_017_D06
  55. Dr_sW_002_O11
  56. Dr_sW_005_G16
  57. Dr_sW_002_G08
  58. Dr_sW_001_N22
  59. Dr_sW_001_J05
  60. Dr_sW_014_J02
  61. Dr_sW_010_P05
  62. Dr_sW_008_B10
  63. Dr_sW_026_A10
  64. Dr_sW_027_B17
  65. Dr_sW_012_C03
  66. Dr_sW_019_M18
  67. Dr_sW_007_O14
  68. Dr_sW_027_F06
  69. Dr_sW_008_M01
  70. Dr_sW_026_F17
  71. Dr_sW_024_G13
  72. Dr_sW_018_F15
  73. Dr_sW_007_A18
  74. Dr_sW_020_P07
  75. Dr_sW_012_O12
  76. Dr_sW_002_J06
  77. Dr_sW_025_L06
  78. Dr_sW_021_D02
  79. Dr_sW_002_F01
  80. Dr_sW_009_G11
  81. Dr_sW_010_F03
  82. Dr_sW_021_K02
  83. Dr_sW_019_J13
  84. Dr_sW_027_D08
  85. Dr_sW_001_B14