Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_010_P05
(324 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P25782|CYSP2_HOMAM Digestive cysteine proteinase 2 precu... 127 1e-29
sp|Q26636|CATL_SARPE Cathepsin L precursor [Contains: Cathe... 126 2e-29
sp|P25784|CYSP3_HOMAM Digestive cysteine proteinase 3 precu... 125 3e-29
sp|P13277|CYSP1_HOMAM Digestive cysteine proteinase 1 precu... 124 9e-29
sp|Q10991|CATL_SHEEP Cathepsin L [Contains: Cathepsin L hea... 123 1e-28
sp|Q95029|CATL_DROME Cathepsin L precursor (Cysteine protei... 122 2e-28
sp|Q9GL24|CATL_CANFA Cathepsin L precursor [Contains: Cathe... 122 3e-28
sp|O60911|CATL2_HUMAN Cathepsin L2 precursor (Cathepsin V) ... 121 4e-28
sp|Q28944|CATL_PIG Cathepsin L precursor [Contains: Catheps... 119 2e-27
sp|P25975|CATL_BOVIN Cathepsin L precursor [Contains: Cathe... 119 2e-27
>sp|P25782|CYSP2_HOMAM Digestive cysteine proteinase 2 precursor
Length = 323
Score = 127 bits (318), Expect = 1e-29
Identities = 54/85 (63%), Positives = 70/85 (82%)
Frame = +1
Query: 1 VSVAIDAGHASFQLYKSGIYNEESCSTTQLDHGVLAVGYGTQIGKKYWIVKNSWDVTWGE 180
+SV IDA H+SFQ Y SG+Y E SCS + LDH VLAVGYG++ G+ +W+VKNSW +WG+
Sbjct: 239 ISVTIDAAHSSFQFYSSGVYYEPSCSPSYLDHAVLAVGYGSEGGQDFWLVKNSWATSWGD 298
Query: 181 SGYIKMSKDKKNQCGIATMASYPLV 255
+GYIKMS+++ N CGIAT+ASYPLV
Sbjct: 299 AGYIKMSRNRNNNCGIATVASYPLV 323
>sp|Q26636|CATL_SARPE Cathepsin L precursor [Contains: Cathepsin L heavy chain; Cathepsin
L light chain]
Length = 339
Score = 126 bits (316), Expect = 2e-29
Identities = 57/86 (66%), Positives = 65/86 (75%), Gaps = 1/86 (1%)
Frame = +1
Query: 1 VSVAIDAGHASFQLYKSGIYNEESCSTTQLDHGVLAVGYGT-QIGKKYWIVKNSWDVTWG 177
VSVAIDA H SFQLY G+YNE C LDHGVL VGYGT + G YW+VKNSW TWG
Sbjct: 254 VSVAIDASHESFQLYSEGVYNEPECDEQNLDHGVLVVGYGTDESGMDYWLVKNSWGTTWG 313
Query: 178 ESGYIKMSKDKKNQCGIATMASYPLV 255
E GYIKM++++ NQCGIAT +SYP V
Sbjct: 314 EQGYIKMARNQNNQCGIATASSYPTV 339
>sp|P25784|CYSP3_HOMAM Digestive cysteine proteinase 3 precursor
Length = 321
Score = 125 bits (314), Expect = 3e-29
Identities = 55/85 (64%), Positives = 68/85 (80%)
Frame = +1
Query: 1 VSVAIDAGHASFQLYKSGIYNEESCSTTQLDHGVLAVGYGTQIGKKYWIVKNSWDVTWGE 180
+SVAIDA H SFQ Y SG+Y E++CS T LDHGVLAVGYGT+ K YW+VKNSW +WG+
Sbjct: 237 ISVAIDASHFSFQFYSSGVYYEQNCSPTFLDHGVLAVGYGTESTKDYWLVKNSWGSSWGD 296
Query: 181 SGYIKMSKDKKNQCGIATMASYPLV 255
+GYIKMS+++ N CGIA+ SYP V
Sbjct: 297 AGYIKMSRNRDNNCGIASEPSYPTV 321
>sp|P13277|CYSP1_HOMAM Digestive cysteine proteinase 1 precursor
Length = 322
Score = 124 bits (310), Expect = 9e-29
Identities = 54/85 (63%), Positives = 69/85 (81%)
Frame = +1
Query: 1 VSVAIDAGHASFQLYKSGIYNEESCSTTQLDHGVLAVGYGTQIGKKYWIVKNSWDVTWGE 180
+SVAIDA H SFQ Y +G+Y E SCS++QLDH VLAVGYG++ G+ +W+VKNSW +WGE
Sbjct: 238 ISVAIDASHRSFQSYYTGVYYEPSCSSSQLDHAVLAVGYGSEGGQDFWLVKNSWATSWGE 297
Query: 181 SGYIKMSKDKKNQCGIATMASYPLV 255
SGYIKM++++ N CGIAT A YP V
Sbjct: 298 SGYIKMARNRNNNCGIATDACYPTV 322
>sp|Q10991|CATL_SHEEP Cathepsin L [Contains: Cathepsin L heavy chain; Cathepsin L light
chain]
Length = 217
Score = 123 bits (309), Expect = 1e-28
Identities = 56/86 (65%), Positives = 65/86 (75%), Gaps = 1/86 (1%)
Frame = +1
Query: 1 VSVAIDAGHASFQLYKSGIYNEESCSTTQLDHGVLAVGYGTQ-IGKKYWIVKNSWDVTWG 177
+SVAIDAGH+SFQ YKSGIY + CS+ LDHGVL VGYG + K+WIVKNSW WG
Sbjct: 132 ISVAIDAGHSSFQFYKSGIYYDPDCSSKDLDHGVLVVGYGFEGTNNKFWIVKNSWGPEWG 191
Query: 178 ESGYIKMSKDKKNQCGIATMASYPLV 255
GY+KM+KD+ N CGIAT ASYP V
Sbjct: 192 NKGYVKMAKDQNNHCGIATAASYPTV 217
>sp|Q95029|CATL_DROME Cathepsin L precursor (Cysteine proteinase 1) [Contains: Cathepsin
L heavy chain; Cathepsin L light chain]
Length = 341
Score = 122 bits (307), Expect = 2e-28
Identities = 54/86 (62%), Positives = 66/86 (76%), Gaps = 1/86 (1%)
Frame = +1
Query: 1 VSVAIDAGHASFQLYKSGIYNEESCSTTQLDHGVLAVGYGT-QIGKKYWIVKNSWDVTWG 177
VSVAIDA H SFQ Y G+YNE C LDHGVL VG+GT + G+ YW+VKNSW TWG
Sbjct: 256 VSVAIDASHESFQFYSEGVYNEPQCDAQNLDHGVLVVGFGTDESGEDYWLVKNSWGTTWG 315
Query: 178 ESGYIKMSKDKKNQCGIATMASYPLV 255
+ G+IKM ++K+NQCGIA+ +SYPLV
Sbjct: 316 DKGFIKMLRNKENQCGIASASSYPLV 341
>sp|Q9GL24|CATL_CANFA Cathepsin L precursor [Contains: Cathepsin L heavy chain; Cathepsin
L light chain]
Length = 333
Score = 122 bits (306), Expect = 3e-28
Identities = 57/88 (64%), Positives = 65/88 (73%), Gaps = 3/88 (3%)
Frame = +1
Query: 1 VSVAIDAGHASFQLYKSGIYNEESCSTTQLDHGVLAVGYG---TQIGKKYWIVKNSWDVT 171
+SVAIDAGH SFQ YKSGIY + CS+ LDHGVL VGYG T K+WIVKNSW
Sbjct: 246 ISVAIDAGHQSFQFYKSGIYFDPDCSSKDLDHGVLVVGYGFEGTDSNNKFWIVKNSWGPE 305
Query: 172 WGESGYIKMSKDKKNQCGIATMASYPLV 255
WG +GY+KM+KD+ N CGIAT ASYP V
Sbjct: 306 WGWNGYVKMAKDQNNHCGIATAASYPTV 333
>sp|O60911|CATL2_HUMAN Cathepsin L2 precursor (Cathepsin V) (Cathepsin U)
Length = 334
Score = 121 bits (304), Expect = 4e-28
Identities = 56/89 (62%), Positives = 66/89 (74%), Gaps = 4/89 (4%)
Frame = +1
Query: 1 VSVAIDAGHASFQLYKSGIYNEESCSTTQLDHGVLAVGYGTQ----IGKKYWIVKNSWDV 168
+SVA+DAGH+SFQ YKSGIY E CS+ LDHGVL VGYG + KYW+VKNSW
Sbjct: 246 ISVAMDAGHSSFQFYKSGIYFEPDCSSKNLDHGVLVVGYGFEGANSNNSKYWLVKNSWGP 305
Query: 169 TWGESGYIKMSKDKKNQCGIATMASYPLV 255
WG +GY+K++KDK N CGIAT ASYP V
Sbjct: 306 EWGSNGYVKIAKDKNNHCGIATAASYPNV 334
>sp|Q28944|CATL_PIG Cathepsin L precursor [Contains: Cathepsin L heavy chain; Cathepsin
L light chain]
Length = 334
Score = 119 bits (299), Expect = 2e-27
Identities = 55/89 (61%), Positives = 66/89 (74%), Gaps = 4/89 (4%)
Frame = +1
Query: 1 VSVAIDAGHASFQLYKSGIYNEESCSTTQLDHGVLAVGYGTQ----IGKKYWIVKNSWDV 168
+SVAIDAGH+SFQ YKSGIY + CS+ LDHGVL VGYG + K+WIVKNSW
Sbjct: 246 ISVAIDAGHSSFQFYKSGIYYDPDCSSKDLDHGVLVVGYGFEGTDSNSSKFWIVKNSWGP 305
Query: 169 TWGESGYIKMSKDKKNQCGIATMASYPLV 255
WG +GY+KM+KD+ N CGI+T ASYP V
Sbjct: 306 EWGWNGYVKMAKDQNNHCGISTAASYPTV 334
>sp|P25975|CATL_BOVIN Cathepsin L precursor [Contains: Cathepsin L heavy chain; Cathepsin
L light chain]
Length = 334
Score = 119 bits (299), Expect = 2e-27
Identities = 56/89 (62%), Positives = 64/89 (71%), Gaps = 4/89 (4%)
Frame = +1
Query: 1 VSVAIDAGHASFQLYKSGIYNEESCSTTQLDHGVLAVGYGTQ----IGKKYWIVKNSWDV 168
+SVAIDAGH SFQ YKSGIY + CS LDHGVL VGYG + K+WIVKNSW
Sbjct: 246 ISVAIDAGHTSFQFYKSGIYYDPDCSCKDLDHGVLVVGYGFEGTDSNNNKFWIVKNSWGP 305
Query: 169 TWGESGYIKMSKDKKNQCGIATMASYPLV 255
WG +GY+KM+KD+ N CGIAT ASYP V
Sbjct: 306 EWGWNGYVKMAKDQNNHCGIATAASYPTV 334
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 38,617,051
Number of Sequences: 369166
Number of extensions: 751795
Number of successful extensions: 2436
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 2252
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 2291
length of database: 68,354,980
effective HSP length: 76
effective length of database: 54,315,120
effective search space used: 1683768720
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)