Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_027_B17
(395 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q26636|CATL_SARPE Cathepsin L precursor [Contains: Cathe... 149 2e-36
sp|Q95029|CATL_DROME Cathepsin L precursor (Cysteine protei... 149 3e-36
sp|P25782|CYSP2_HOMAM Digestive cysteine proteinase 2 precu... 147 1e-35
sp|Q10991|CATL_SHEEP Cathepsin L [Contains: Cathepsin L hea... 145 2e-35
sp|O60911|CATL2_HUMAN Cathepsin L2 precursor (Cathepsin V) ... 143 1e-34
sp|Q9GL24|CATL_CANFA Cathepsin L precursor [Contains: Cathe... 142 2e-34
sp|Q28944|CATL_PIG Cathepsin L precursor [Contains: Catheps... 142 3e-34
sp|P25975|CATL_BOVIN Cathepsin L precursor [Contains: Cathe... 142 3e-34
sp|P25784|CYSP3_HOMAM Digestive cysteine proteinase 3 precu... 139 2e-33
sp|P13277|CYSP1_HOMAM Digestive cysteine proteinase 1 precu... 139 2e-33
>sp|Q26636|CATL_SARPE Cathepsin L precursor [Contains: Cathepsin L heavy chain; Cathepsin
L light chain]
Length = 339
Score = 149 bits (376), Expect = 2e-36
Identities = 69/109 (63%), Positives = 80/109 (73%), Gaps = 1/109 (0%)
Frame = +3
Query: 3 TGFTDIQSQNETDLANAVATVGPVSVAIDAGHASFQLYKSGIYNEESCSTTQLDHGVLAV 182
TGF DI +E + AVAT+GPVSVAIDA H SFQLY G+YNE C LDHGVL V
Sbjct: 231 TGFVDIPEGDEEKMKKAVATMGPVSVAIDASHESFQLYSEGVYNEPECDEQNLDHGVLVV 290
Query: 183 GYGT-QIGKKYWIVKNSWDVTWGESGYIKMSKDKKNQCGIATMASYPLV 326
GYGT + G YW+VKNSW TWGE GYIKM++++ NQCGIAT +SYP V
Sbjct: 291 GYGTDESGMDYWLVKNSWGTTWGEQGYIKMARNQNNQCGIATASSYPTV 339
>sp|Q95029|CATL_DROME Cathepsin L precursor (Cysteine proteinase 1) [Contains: Cathepsin
L heavy chain; Cathepsin L light chain]
Length = 341
Score = 149 bits (375), Expect = 3e-36
Identities = 68/108 (62%), Positives = 82/108 (75%), Gaps = 1/108 (0%)
Frame = +3
Query: 6 GFTDIQSQNETDLANAVATVGPVSVAIDAGHASFQLYKSGIYNEESCSTTQLDHGVLAVG 185
GFTDI +E +A AVATVGPVSVAIDA H SFQ Y G+YNE C LDHGVL VG
Sbjct: 234 GFTDIPQGDEKKMAEAVATVGPVSVAIDASHESFQFYSEGVYNEPQCDAQNLDHGVLVVG 293
Query: 186 YGT-QIGKKYWIVKNSWDVTWGESGYIKMSKDKKNQCGIATMASYPLV 326
+GT + G+ YW+VKNSW TWG+ G+IKM ++K+NQCGIA+ +SYPLV
Sbjct: 294 FGTDESGEDYWLVKNSWGTTWGDKGFIKMLRNKENQCGIASASSYPLV 341
>sp|P25782|CYSP2_HOMAM Digestive cysteine proteinase 2 precursor
Length = 323
Score = 147 bits (370), Expect = 1e-35
Identities = 65/108 (60%), Positives = 85/108 (78%)
Frame = +3
Query: 3 TGFTDIQSQNETDLANAVATVGPVSVAIDAGHASFQLYKSGIYNEESCSTTQLDHGVLAV 182
+G T+I S +ET L AV +GP+SV IDA H+SFQ Y SG+Y E SCS + LDH VLAV
Sbjct: 216 SGHTNIASGSETGLQQAVRDIGPISVTIDAAHSSFQFYSSGVYYEPSCSPSYLDHAVLAV 275
Query: 183 GYGTQIGKKYWIVKNSWDVTWGESGYIKMSKDKKNQCGIATMASYPLV 326
GYG++ G+ +W+VKNSW +WG++GYIKMS+++ N CGIAT+ASYPLV
Sbjct: 276 GYGSEGGQDFWLVKNSWATSWGDAGYIKMSRNRNNNCGIATVASYPLV 323
>sp|Q10991|CATL_SHEEP Cathepsin L [Contains: Cathepsin L heavy chain; Cathepsin L light
chain]
Length = 217
Score = 145 bits (367), Expect = 2e-35
Identities = 71/109 (65%), Positives = 80/109 (73%), Gaps = 1/109 (0%)
Frame = +3
Query: 3 TGFTDIQSQNETDLANAVATVGPVSVAIDAGHASFQLYKSGIYNEESCSTTQLDHGVLAV 182
TGF DI Q E L AVATVGP+SVAIDAGH+SFQ YKSGIY + CS+ LDHGVL V
Sbjct: 110 TGFVDIP-QREKALMKAVATVGPISVAIDAGHSSFQFYKSGIYYDPDCSSKDLDHGVLVV 168
Query: 183 GYGTQ-IGKKYWIVKNSWDVTWGESGYIKMSKDKKNQCGIATMASYPLV 326
GYG + K+WIVKNSW WG GY+KM+KD+ N CGIAT ASYP V
Sbjct: 169 GYGFEGTNNKFWIVKNSWGPEWGNKGYVKMAKDQNNHCGIATAASYPTV 217
>sp|O60911|CATL2_HUMAN Cathepsin L2 precursor (Cathepsin V) (Cathepsin U)
Length = 334
Score = 143 bits (361), Expect = 1e-34
Identities = 69/112 (61%), Positives = 79/112 (70%), Gaps = 4/112 (3%)
Frame = +3
Query: 3 TGFTDIQSQNETDLANAVATVGPVSVAIDAGHASFQLYKSGIYNEESCSTTQLDHGVLAV 182
TGFT + E L AVATVGP+SVA+DAGH+SFQ YKSGIY E CS+ LDHGVL V
Sbjct: 223 TGFTVVAPGKEKALMKAVATVGPISVAMDAGHSSFQFYKSGIYFEPDCSSKNLDHGVLVV 282
Query: 183 GYG----TQIGKKYWIVKNSWDVTWGESGYIKMSKDKKNQCGIATMASYPLV 326
GYG KYW+VKNSW WG +GY+K++KDK N CGIAT ASYP V
Sbjct: 283 GYGFEGANSNNSKYWLVKNSWGPEWGSNGYVKIAKDKNNHCGIATAASYPNV 334
>sp|Q9GL24|CATL_CANFA Cathepsin L precursor [Contains: Cathepsin L heavy chain; Cathepsin
L light chain]
Length = 333
Score = 142 bits (359), Expect = 2e-34
Identities = 70/111 (63%), Positives = 80/111 (72%), Gaps = 3/111 (2%)
Frame = +3
Query: 3 TGFTDIQSQNETDLANAVATVGPVSVAIDAGHASFQLYKSGIYNEESCSTTQLDHGVLAV 182
TGF D+ Q E L AVAT+GP+SVAIDAGH SFQ YKSGIY + CS+ LDHGVL V
Sbjct: 224 TGFVDLP-QREKALMKAVATLGPISVAIDAGHQSFQFYKSGIYFDPDCSSKDLDHGVLVV 282
Query: 183 GY---GTQIGKKYWIVKNSWDVTWGESGYIKMSKDKKNQCGIATMASYPLV 326
GY GT K+WIVKNSW WG +GY+KM+KD+ N CGIAT ASYP V
Sbjct: 283 GYGFEGTDSNNKFWIVKNSWGPEWGWNGYVKMAKDQNNHCGIATAASYPTV 333
>sp|Q28944|CATL_PIG Cathepsin L precursor [Contains: Cathepsin L heavy chain; Cathepsin
L light chain]
Length = 334
Score = 142 bits (357), Expect = 3e-34
Identities = 70/112 (62%), Positives = 81/112 (72%), Gaps = 4/112 (3%)
Frame = +3
Query: 3 TGFTDIQSQNETDLANAVATVGPVSVAIDAGHASFQLYKSGIYNEESCSTTQLDHGVLAV 182
TGF DI Q E L AVATVGP+SVAIDAGH+SFQ YKSGIY + CS+ LDHGVL V
Sbjct: 224 TGFVDIP-QREKALMKAVATVGPISVAIDAGHSSFQFYKSGIYYDPDCSSKDLDHGVLVV 282
Query: 183 GYGTQ----IGKKYWIVKNSWDVTWGESGYIKMSKDKKNQCGIATMASYPLV 326
GYG + K+WIVKNSW WG +GY+KM+KD+ N CGI+T ASYP V
Sbjct: 283 GYGFEGTDSNSSKFWIVKNSWGPEWGWNGYVKMAKDQNNHCGISTAASYPTV 334
>sp|P25975|CATL_BOVIN Cathepsin L precursor [Contains: Cathepsin L heavy chain; Cathepsin
L light chain]
Length = 334
Score = 142 bits (357), Expect = 3e-34
Identities = 71/112 (63%), Positives = 79/112 (70%), Gaps = 4/112 (3%)
Frame = +3
Query: 3 TGFTDIQSQNETDLANAVATVGPVSVAIDAGHASFQLYKSGIYNEESCSTTQLDHGVLAV 182
TGF DI Q E L AVATVGP+SVAIDAGH SFQ YKSGIY + CS LDHGVL V
Sbjct: 224 TGFVDIP-QREKALMKAVATVGPISVAIDAGHTSFQFYKSGIYYDPDCSCKDLDHGVLVV 282
Query: 183 GYGTQ----IGKKYWIVKNSWDVTWGESGYIKMSKDKKNQCGIATMASYPLV 326
GYG + K+WIVKNSW WG +GY+KM+KD+ N CGIAT ASYP V
Sbjct: 283 GYGFEGTDSNNNKFWIVKNSWGPEWGWNGYVKMAKDQNNHCGIATAASYPTV 334
>sp|P25784|CYSP3_HOMAM Digestive cysteine proteinase 3 precursor
Length = 321
Score = 139 bits (351), Expect = 2e-33
Identities = 65/108 (60%), Positives = 81/108 (75%)
Frame = +3
Query: 3 TGFTDIQSQNETDLANAVATVGPVSVAIDAGHASFQLYKSGIYNEESCSTTQLDHGVLAV 182
TG ++Q E L AV+ VGP+SVAIDA H SFQ Y SG+Y E++CS T LDHGVLAV
Sbjct: 215 TGSVEVQHTEEA-LQEAVSGVGPISVAIDASHFSFQFYSSGVYYEQNCSPTFLDHGVLAV 273
Query: 183 GYGTQIGKKYWIVKNSWDVTWGESGYIKMSKDKKNQCGIATMASYPLV 326
GYGT+ K YW+VKNSW +WG++GYIKMS+++ N CGIA+ SYP V
Sbjct: 274 GYGTESTKDYWLVKNSWGSSWGDAGYIKMSRNRDNNCGIASEPSYPTV 321
>sp|P13277|CYSP1_HOMAM Digestive cysteine proteinase 1 precursor
Length = 322
Score = 139 bits (350), Expect = 2e-33
Identities = 62/108 (57%), Positives = 81/108 (75%)
Frame = +3
Query: 3 TGFTDIQSQNETDLANAVATVGPVSVAIDAGHASFQLYKSGIYNEESCSTTQLDHGVLAV 182
TG+ I +E+ L A +GP+SVAIDA H SFQ Y +G+Y E SCS++QLDH VLAV
Sbjct: 215 TGYVGIAQGSESALKTATRDIGPISVAIDASHRSFQSYYTGVYYEPSCSSSQLDHAVLAV 274
Query: 183 GYGTQIGKKYWIVKNSWDVTWGESGYIKMSKDKKNQCGIATMASYPLV 326
GYG++ G+ +W+VKNSW +WGESGYIKM++++ N CGIAT A YP V
Sbjct: 275 GYGSEGGQDFWLVKNSWATSWGESGYIKMARNRNNNCGIATDACYPTV 322
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 45,920,405
Number of Sequences: 369166
Number of extensions: 891512
Number of successful extensions: 2900
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 2669
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 2716
length of database: 68,354,980
effective HSP length: 97
effective length of database: 50,435,685
effective search space used: 1714813290
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)