Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_018_K12
(925 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|O60911|CATL2_HUMAN Cathepsin L2 precursor (Cathepsin V) ... 275 2e-73
sp|P07711|CATL_HUMAN Cathepsin L precursor (Major excreted ... 271 2e-72
sp|Q9GL24|CATL_CANFA Cathepsin L precursor [Contains: Cathe... 271 2e-72
sp|P25975|CATL_BOVIN Cathepsin L precursor [Contains: Cathe... 268 1e-71
sp|Q28944|CATL_PIG Cathepsin L precursor [Contains: Catheps... 265 2e-70
sp|Q26636|CATL_SARPE Cathepsin L precursor [Contains: Cathe... 259 6e-69
sp|Q24940|CATLP_FASHE Cathepsin L-like proteinase precursor 259 7e-69
sp|P06797|CATL_MOUSE Cathepsin L precursor (Major excreted ... 256 5e-68
sp|P07154|CATL_RAT Cathepsin L precursor (Major excreted pr... 256 5e-68
sp|Q9GLE3|CATK_PIG Cathepsin K precursor 256 6e-68
>sp|O60911|CATL2_HUMAN Cathepsin L2 precursor (Cathepsin V) (Cathepsin U)
Length = 334
Score = 275 bits (702), Expect = 2e-73
Identities = 142/275 (51%), Positives = 179/275 (65%), Gaps = 1/275 (0%)
Frame = +1
Query: 19 TAVPQKFSVNSELNEEWETYKTTFGRKYDELTDITRRLIWEQNLKYIQKHNLEYDLGKHT 198
+AVP KF N L+ +W +K T R Y + RR +WE+N+K I+ HN EY GKH
Sbjct: 16 SAVP-KFDQN--LDTKWYQWKATHRRLYGANEEGWRRAVWEKNMKMIELHNGEYSQGKHG 72
Query: 199 YSLGLNQFADMTNEEFKAKYLGIMKTKPTLEGSTYMAPENIGVLPASVDWRQKGYVTPVK 378
+++ +N F DMTNEEF+ + +G + + +G + P + LP SVDWR+KGYVTPVK
Sbjct: 73 FTMAMNAFGDMTNEEFR-QMMGCFRNQKFRKGKVFREPLFLD-LPKSVDWRKKGYVTPVK 130
Query: 379 NQQQCGSCWSFSATGSLEGQYFRKNNRLISFSEQQLVDCSXXXXXXXXXXXLMDNAFRYI 558
NQ+QCGSCW+FSATG+LEGQ FRK +L+S SEQ LVDCS M AF+Y+
Sbjct: 131 NQKQCGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSRPQGNQGCNGGFMARAFQYV 190
Query: 559 KDQ-GIESEGDYPYTATDGTCKRNPSKIVTKCTGFTDIQSQNETDLANAVATVGPVSVAI 735
K+ G++SE YPY A D CK P V TGFT + E L AVATVGP+SVA+
Sbjct: 191 KENGGLDSEESYPYVAVDEICKYRPENSVANDTGFTVVAPGKEKALMKAVATVGPISVAM 250
Query: 736 DAGHASFQLYKSGIYNEESCSTTQLDHGVLAVGYG 840
DAGH+SFQ YKSGIY E CS+ LDHGVL VGYG
Sbjct: 251 DAGHSSFQFYKSGIYFEPDCSSKNLDHGVLVVGYG 285
Score = 44.3 bits (103), Expect = 5e-04
Identities = 16/27 (59%), Positives = 21/27 (77%)
Frame = +3
Query: 843 SNWKKYWIVKNSWDVTWGESGYIKMSK 923
SN KYW+VKNSW WG +GY+K++K
Sbjct: 291 SNNSKYWLVKNSWGPEWGSNGYVKIAK 317
>sp|P07711|CATL_HUMAN Cathepsin L precursor (Major excreted protein) (MEP) [Contains:
Cathepsin L heavy chain; Cathepsin L light chain]
Length = 333
Score = 271 bits (693), Expect = 2e-72
Identities = 140/263 (53%), Positives = 169/263 (64%), Gaps = 1/263 (0%)
Frame = +1
Query: 55 LNEEWETYKTTFGRKYDELTDITRRLIWEQNLKYIQKHNLEYDLGKHTYSLGLNQFADMT 234
L +W +K R Y + RR +WE+N+K I+ HN EY GKH++++ +N F DMT
Sbjct: 25 LEAQWTKWKAMHNRLYGMNEEGWRRAVWEKNMKMIELHNQEYREGKHSFTMAMNAFGDMT 84
Query: 235 NEEFKAKYLGIMKTKPTLEGSTYMAPENIGVLPASVDWRQKGYVTPVKNQQQCGSCWSFS 414
+EEF+ G KP +G + P P SVDWR+KGYVTPVKNQ QCGSCW+FS
Sbjct: 85 SEEFRQVMNGFQNRKPR-KGKVFQEPLFYEA-PRSVDWREKGYVTPVKNQGQCGSCWAFS 142
Query: 415 ATGSLEGQYFRKNNRLISFSEQQLVDCSXXXXXXXXXXXLMDNAFRYIKDQ-GIESEGDY 591
ATG+LEGQ FRK RLIS SEQ LVDCS LMD AF+Y++D G++SE Y
Sbjct: 143 ATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNGGLMDYAFQYVQDNGGLDSEESY 202
Query: 592 PYTATDGTCKRNPSKIVTKCTGFTDIQSQNETDLANAVATVGPVSVAIDAGHASFQLYKS 771
PY AT+ +CK NP V TGF DI Q E L AVATVGP+SVAIDAGH SF YK
Sbjct: 203 PYEATEESCKYNPKYSVANDTGFVDIPKQ-EKALMKAVATVGPISVAIDAGHESFLFYKE 261
Query: 772 GIYNEESCSTTQLDHGVLAVGYG 840
GIY E CS+ +DHGVL VGYG
Sbjct: 262 GIYFEPDCSSEDMDHGVLVVGYG 284
Score = 42.7 bits (99), Expect = 0.001
Identities = 16/27 (59%), Positives = 20/27 (74%)
Frame = +3
Query: 843 SNWKKYWIVKNSWDVTWGESGYIKMSK 923
S+ KYW+VKNSW WG GY+KM+K
Sbjct: 290 SDNNKYWLVKNSWGEEWGMGGYVKMAK 316
>sp|Q9GL24|CATL_CANFA Cathepsin L precursor [Contains: Cathepsin L heavy chain; Cathepsin
L light chain]
Length = 333
Score = 271 bits (693), Expect = 2e-72
Identities = 143/279 (51%), Positives = 174/279 (62%), Gaps = 2/279 (0%)
Frame = +1
Query: 10 VAITAVPQKFSVNSELNEEWETYKTTFGRKYDELTDITRRLIWEQNLKYIQKHNLEYDLG 189
+ I + KF + LN +W +K T R Y + RR +WE+N+K I+ HN EY G
Sbjct: 12 LGIASAAPKF--DQSLNAQWYQWKATHRRLYGMNEEGWRRAVWEKNMKMIELHNREYSQG 69
Query: 190 KHTYSLGLNQFADMTNEEFKAKYLGIMKTKPTLEGSTYMAPENIGVLPASVDWRQKGYVT 369
KH +++ +N F DMTNEEF+ G K +G + P +P SVDWR+KGYVT
Sbjct: 70 KHGFTMAMNAFGDMTNEEFRQVMNGFQNQKHK-KGKMFQEPL-FAEIPKSVDWREKGYVT 127
Query: 370 PVKNQQQCGSCWSFSATGSLEGQYFRKNNRLISFSEQQLVDCSXXXXXXXXXXXLMDNAF 549
PVKNQ QCGSCW+FSATG+LEGQ FRK +L+S SEQ LVDCS LMDNAF
Sbjct: 128 PVKNQGQCGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSRAQGNEGCNGGLMDNAF 187
Query: 550 RYIKDQ-GIESEGDYPYTATD-GTCKRNPSKIVTKCTGFTDIQSQNETDLANAVATVGPV 723
RY+KD G++SE YPY D TC P TGF D+ Q E L AVAT+GP+
Sbjct: 188 RYVKDNGGLDSEESYPYLGRDTETCNYKPECSAANDTGFVDL-PQREKALMKAVATLGPI 246
Query: 724 SVAIDAGHASFQLYKSGIYNEESCSTTQLDHGVLAVGYG 840
SVAIDAGH SFQ YKSGIY + CS+ LDHGVL VGYG
Sbjct: 247 SVAIDAGHQSFQFYKSGIYFDPDCSSKDLDHGVLVVGYG 285
Score = 41.6 bits (96), Expect = 0.003
Identities = 15/23 (65%), Positives = 19/23 (82%)
Frame = +3
Query: 855 KYWIVKNSWDVTWGESGYIKMSK 923
K+WIVKNSW WG +GY+KM+K
Sbjct: 294 KFWIVKNSWGPEWGWNGYVKMAK 316
>sp|P25975|CATL_BOVIN Cathepsin L precursor [Contains: Cathepsin L heavy chain; Cathepsin
L light chain]
Length = 334
Score = 268 bits (686), Expect = 1e-71
Identities = 144/282 (51%), Positives = 171/282 (60%), Gaps = 2/282 (0%)
Frame = +1
Query: 1 LVVVAITAVPQKFSVNSELNEEWETYKTTFGRKYDELTDITRRLIWEQNLKYIQKHNLEY 180
L V+ + ++ L+ W +K T R Y + RR +WE+N K I HN EY
Sbjct: 7 LTVLCLGVASAAPKLDPNLDAHWHQWKATHRRLYGMNEEEWRRAVWEKNKKIIDLHNQEY 66
Query: 181 DLGKHTYSLGLNQFADMTNEEFKAKYLGIMKTKPTLEGSTYMAPENIGVLPASVDWRQKG 360
GKH + + +N F DMTNEEF+ G K +G + P + V P SVDW +KG
Sbjct: 67 SEGKHAFRMAMNAFGDMTNEEFRQVMNGFQNQKHK-KGKLFHEPLLVDV-PKSVDWTKKG 124
Query: 361 YVTPVKNQQQCGSCWSFSATGSLEGQYFRKNNRLISFSEQQLVDCSXXXXXXXXXXXLMD 540
YVTPVKNQ QCGSCW+FSATG+LEGQ FRK +L+S SEQ LVDCS LMD
Sbjct: 125 YVTPVKNQGQCGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSRAQGNQGCNGGLMD 184
Query: 541 NAFRYIKDQ-GIESEGDYPYTATD-GTCKRNPSKIVTKCTGFTDIQSQNETDLANAVATV 714
NAF+YIKD G++SE YPY ATD +C P TGF DI Q E L AVATV
Sbjct: 185 NAFQYIKDNGGLDSEESYPYLATDTNSCNYKPECSAANDTGFVDI-PQREKALMKAVATV 243
Query: 715 GPVSVAIDAGHASFQLYKSGIYNEESCSTTQLDHGVLAVGYG 840
GP+SVAIDAGH SFQ YKSGIY + CS LDHGVL VGYG
Sbjct: 244 GPISVAIDAGHTSFQFYKSGIYYDPDCSCKDLDHGVLVVGYG 285
Score = 43.9 bits (102), Expect = 6e-04
Identities = 17/27 (62%), Positives = 21/27 (77%)
Frame = +3
Query: 843 SNWKKYWIVKNSWDVTWGESGYIKMSK 923
SN K+WIVKNSW WG +GY+KM+K
Sbjct: 291 SNNNKFWIVKNSWGPEWGWNGYVKMAK 317
>sp|Q28944|CATL_PIG Cathepsin L precursor [Contains: Cathepsin L heavy chain; Cathepsin
L light chain]
Length = 334
Score = 265 bits (676), Expect = 2e-70
Identities = 138/268 (51%), Positives = 171/268 (63%), Gaps = 2/268 (0%)
Frame = +1
Query: 43 VNSELNEEWETYKTTFGRKYDELTDITRRLIWEQNLKYIQKHNLEYDLGKHTYSLGLNQF 222
++ L+ +W +K T GR Y + RR +WE+N+K I+ HN EY GKH +S+ +N F
Sbjct: 21 LDQNLDADWYKWKATHGRLYGMNEEGWRRAVWEKNMKMIELHNQEYSQGKHGFSMAMNAF 80
Query: 223 ADMTNEEFKAKYLGIMKTKPTLEGSTYMAPENIGVLPASVDWRQKGYVTPVKNQQQCGSC 402
DMTNEEF+ G K +G + + V P SVDWR+KGYVT VKNQ QCGSC
Sbjct: 81 GDMTNEEFRQVMNGFQNQKHK-KGKVFHESLVLEV-PKSVDWREKGYVTAVKNQGQCGSC 138
Query: 403 WSFSATGSLEGQYFRKNNRLISFSEQQLVDCSXXXXXXXXXXXLMDNAFRYIKDQ-GIES 579
W+FSATG+LEGQ FRK +L+S SEQ LVDCS LMDNAF+Y+KD G+++
Sbjct: 139 WAFSATGALEGQMFRKTGKLVSLSEQNLVDCSRPQGNQGCNGGLMDNAFQYVKDNGGLDT 198
Query: 580 EGDYPYTATD-GTCKRNPSKIVTKCTGFTDIQSQNETDLANAVATVGPVSVAIDAGHASF 756
E YPY + +C P TGF DI Q E L AVATVGP+SVAIDAGH+SF
Sbjct: 199 EESYPYLGRETNSCTYKPECSAANDTGFVDI-PQREKALMKAVATVGPISVAIDAGHSSF 257
Query: 757 QLYKSGIYNEESCSTTQLDHGVLAVGYG 840
Q YKSGIY + CS+ LDHGVL VGYG
Sbjct: 258 QFYKSGIYYDPDCSSKDLDHGVLVVGYG 285
Score = 44.3 bits (103), Expect = 5e-04
Identities = 17/27 (62%), Positives = 21/27 (77%)
Frame = +3
Query: 843 SNWKKYWIVKNSWDVTWGESGYIKMSK 923
SN K+WIVKNSW WG +GY+KM+K
Sbjct: 291 SNSSKFWIVKNSWGPEWGWNGYVKMAK 317
>sp|Q26636|CATL_SARPE Cathepsin L precursor [Contains: Cathepsin L heavy chain; Cathepsin
L light chain]
Length = 339
Score = 259 bits (663), Expect = 6e-69
Identities = 140/290 (48%), Positives = 179/290 (61%), Gaps = 9/290 (3%)
Frame = +1
Query: 1 LVVVAITAVPQKFSVNSELNEEWETYKTTFGRKY-DELTDITRRLIWEQNLKYIQKHNLE 177
+ ++A+ A+ Q S + EEW TYK + Y +E+ + R I+ +N I KHN
Sbjct: 6 VALLALVALTQAISPLDLIKEEWHTYKLQHRKNYANEVEERFRMKIFNENRHKIAKHNQL 65
Query: 178 YDLGKHTYSLGLNQFADMTNEEFKAKYLG-------IMKTKPTLEGSTYMAPENIGVLPA 336
+ GK +Y LGLN++ADM + EFK G +M+ + L G+TY+ P ++ V P
Sbjct: 66 FAQGKVSYKLGLNKYADMLHHEFKETMNGYNHTLRQLMRERTGLVGATYIPPAHVTV-PK 124
Query: 337 SVDWRQKGYVTPVKNQQQCGSCWSFSATGSLEGQYFRKNNRLISFSEQQLVDCSXXXXXX 516
SVDWR+ G VT VK+Q CGSCW+FS+TG+LEGQ+FRK L+S SEQ LVDCS
Sbjct: 125 SVDWREHGAVTGVKDQGHCGSCWAFSSTGALEGQHFRKAGVLVSLSEQNLVDCSTKYGNN 184
Query: 517 XXXXXLMDNAFRYIKDQG-IESEGDYPYTATDGTCKRNPSKIVTKCTGFTDIQSQNETDL 693
LMDNAFRYIKD G I++E YPY D +C N + I TGF DI +E +
Sbjct: 185 GCNGGLMDNAFRYIKDNGGIDTEKSYPYEGIDDSCHFNKATIGATDTGFVDIPEGDEEKM 244
Query: 694 ANAVATVGPVSVAIDAGHASFQLYKSGIYNEESCSTTQLDHGVLAVGYGT 843
AVAT+GPVSVAIDA H SFQLY G+YNE C LDHGVL VGYGT
Sbjct: 245 KKAVATMGPVSVAIDASHESFQLYSEGVYNEPECDEQNLDHGVLVVGYGT 294
Score = 45.4 bits (106), Expect = 2e-04
Identities = 16/22 (72%), Positives = 19/22 (86%)
Frame = +3
Query: 858 YWIVKNSWDVTWGESGYIKMSK 923
YW+VKNSW TWGE GYIKM++
Sbjct: 301 YWLVKNSWGTTWGEQGYIKMAR 322
>sp|Q24940|CATLP_FASHE Cathepsin L-like proteinase precursor
Length = 326
Score = 259 bits (662), Expect = 7e-69
Identities = 126/269 (46%), Positives = 171/269 (63%)
Frame = +1
Query: 67 WETYKTTFGRKYDELTDITRRLIWEQNLKYIQKHNLEYDLGKHTYSLGLNQFADMTNEEF 246
W +K + ++Y+ D RR IWE+N+K+IQ+HNL +DLG TY+LGLNQF DMT EEF
Sbjct: 21 WHQWKRMYNKEYNGADDQHRRNIWEKNVKHIQEHNLRHDLGLVTYTLGLNQFTDMTFEEF 80
Query: 247 KAKYLGIMKTKPTLEGSTYMAPENIGVLPASVDWRQKGYVTPVKNQQQCGSCWSFSATGS 426
KAKYL M + N +P +DWR+ GYVT VK+Q CGSCW+FS TG+
Sbjct: 81 KAKYLTEMSRASDILSHGVPYEANNRAVPDKIDWRESGYVTEVKDQGNCGSCWAFSTTGT 140
Query: 427 LEGQYFRKNNRLISFSEQQLVDCSXXXXXXXXXXXLMDNAFRYIKDQGIESEGDYPYTAT 606
+EGQY + ISFSEQQLVDCS LM+NA++Y+K G+E+E YPYTA
Sbjct: 141 MEGQYMKNERTSISFSEQQLVDCSGPWGNNGCSGGLMENAYQYLKQFGLETESSYPYTAV 200
Query: 607 DGTCKRNPSKIVTKCTGFTDIQSQNETDLANAVATVGPVSVAIDAGHASFQLYKSGIYNE 786
+G C+ N V K TG+ + S +E +L N V P +VA+D + F +Y+SGIY
Sbjct: 201 EGQCRYNKQLGVAKVTGYYTVHSGSEVELKNLVGARRPAAVAVDV-ESDFMMYRSGIYQS 259
Query: 787 ESCSTTQLDHGVLAVGYGTQIGKNTGLLK 873
++CS +++H VLAVGYGTQ G + ++K
Sbjct: 260 QTCSPLRVNHAVLAVGYGTQGGTDYWIVK 288
Score = 42.0 bits (97), Expect = 0.002
Identities = 15/22 (68%), Positives = 18/22 (81%)
Frame = +3
Query: 858 YWIVKNSWDVTWGESGYIKMSK 923
YWIVKNSW WGE GYI+M++
Sbjct: 284 YWIVKNSWGTYWGERGYIRMAR 305
>sp|P06797|CATL_MOUSE Cathepsin L precursor (Major excreted protein) (MEP) (p39 cysteine
proteinase) [Contains: Cathepsin L heavy chain;
Cathepsin L light chain]
Length = 334
Score = 256 bits (655), Expect = 5e-68
Identities = 137/260 (52%), Positives = 165/260 (63%), Gaps = 1/260 (0%)
Frame = +1
Query: 64 EWETYKTTFGRKYDELTDITRRLIWEQNLKYIQKHNLEYDLGKHTYSLGLNQFADMTNEE 243
EW +K+T R Y + RR IWE+N++ IQ HN EY G+H +S+ +N F DMTNEE
Sbjct: 28 EWHQWKSTHRRLYGTNEEEWRRAIWEKNMRMIQLHNGEYSNGQHGFSMEMNAFGDMTNEE 87
Query: 244 FKAKYLGIMKTKPTLEGSTYMAPENIGVLPASVDWRQKGYVTPVKNQQQCGSCWSFSATG 423
F+ G K +G + P + + P SVDWR+KG VTPVKNQ QCGSCW+FSA+G
Sbjct: 88 FRQVVNGYRHQKHK-KGRLFQEPLMLKI-PKSVDWREKGCVTPVKNQGQCGSCWAFSASG 145
Query: 424 SLEGQYFRKNNRLISFSEQQLVDCSXXXXXXXXXXXLMDNAFRYIKDQ-GIESEGDYPYT 600
LEGQ F K +LIS SEQ LVDCS LMD AF+YIK+ G++SE YPY
Sbjct: 146 CLEGQMFLKTGKLISLSEQNLVDCSHAQGNQGCNGGLMDFAFQYIKENGGLDSEESYPYE 205
Query: 601 ATDGTCKRNPSKIVTKCTGFTDIQSQNETDLANAVATVGPVSVAIDAGHASFQLYKSGIY 780
A DG+CK V TGF DI Q E L AVATVGP+SVA+DA H S Q Y SGIY
Sbjct: 206 AKDGSCKYRAEFAVANDTGFVDI-PQQEKALMKAVATVGPISVAMDASHPSLQFYSSGIY 264
Query: 781 NEESCSTTQLDHGVLAVGYG 840
E +CS+ LDHGVL VGYG
Sbjct: 265 YEPNCSSKNLDHGVLLVGYG 284
Score = 43.9 bits (102), Expect = 6e-04
Identities = 17/27 (62%), Positives = 20/27 (74%)
Frame = +3
Query: 843 SNWKKYWIVKNSWDVTWGESGYIKMSK 923
SN KYW+VKNSW WG GYIK++K
Sbjct: 290 SNKNKYWLVKNSWGSEWGMEGYIKIAK 316
>sp|P07154|CATL_RAT Cathepsin L precursor (Major excreted protein) (MEP) (Cyclic
protein 2) (CP-2) [Contains: Cathepsin L heavy chain;
Cathepsin L light chain]
Length = 334
Score = 256 bits (655), Expect = 5e-68
Identities = 135/262 (51%), Positives = 166/262 (63%), Gaps = 1/262 (0%)
Frame = +1
Query: 58 NEEWETYKTTFGRKYDELTDITRRLIWEQNLKYIQKHNLEYDLGKHTYSLGLNQFADMTN 237
N +W +K+T R Y + RR +WE+N++ IQ HN EY GKH +++ +N F DMTN
Sbjct: 26 NAQWHQWKSTHRRLYGTNEEEWRRAVWEKNMRMIQLHNGEYSNGKHGFTMEMNAFGDMTN 85
Query: 238 EEFKAKYLGIMKTKPTLEGSTYMAPENIGVLPASVDWRQKGYVTPVKNQQQCGSCWSFSA 417
EEF+ G K +G + P + + P +VDWR+KG VTPVKNQ QCGSCW+FSA
Sbjct: 86 EEFRQIVNGYRHQKHK-KGRLFQEPLMLQI-PKTVDWREKGCVTPVKNQGQCGSCWAFSA 143
Query: 418 TGSLEGQYFRKNNRLISFSEQQLVDCSXXXXXXXXXXXLMDNAFRYIKDQ-GIESEGDYP 594
+G LEGQ F K +LIS SEQ LVDCS LMD AF+YIK+ G++SE YP
Sbjct: 144 SGCLEGQMFLKTGKLISLSEQNLVDCSHDQGNQGCNGGLMDFAFQYIKENGGLDSEESYP 203
Query: 595 YTATDGTCKRNPSKIVTKCTGFTDIQSQNETDLANAVATVGPVSVAIDAGHASFQLYKSG 774
Y A DG+CK V TGF DI Q E L AVATVGP+SVA+DA H S Q Y SG
Sbjct: 204 YEAKDGSCKYRAEYAVANDTGFVDI-PQQEKALMKAVATVGPISVAMDASHPSLQFYSSG 262
Query: 775 IYNEESCSTTQLDHGVLAVGYG 840
IY E +CS+ LDHGVL VGYG
Sbjct: 263 IYYEPNCSSKDLDHGVLVVGYG 284
Score = 43.5 bits (101), Expect = 8e-04
Identities = 17/27 (62%), Positives = 20/27 (74%)
Frame = +3
Query: 843 SNWKKYWIVKNSWDVTWGESGYIKMSK 923
SN KYW+VKNSW WG GYIK++K
Sbjct: 290 SNKDKYWLVKNSWGKEWGMDGYIKIAK 316
>sp|Q9GLE3|CATK_PIG Cathepsin K precursor
Length = 330
Score = 256 bits (654), Expect = 6e-68
Identities = 137/294 (46%), Positives = 181/294 (61%), Gaps = 4/294 (1%)
Frame = +1
Query: 4 VVVAITAVPQKFSVNSELNEEWETYKTTFGRKYDELTD-ITRRLIWEQNLKYIQKHNLEY 180
VV+ + + L+ +WE +K T+ ++Y+ D I+RRLIWE+NLK+I HNLE
Sbjct: 6 VVLLLPVMSSALYPEEILDTQWELWKKTYRKQYNSKVDEISRRLIWEKNLKHISIHNLEA 65
Query: 181 DLGKHTYSLGLNQFADMTNEEFKAKYLGIMKTKPTLEGS--TYMAPENIGVLPASVDWRQ 354
LG HTY L +N DMT+EE K G+ K P+ S T P+ G P S+D+R+
Sbjct: 66 SLGVHTYELAMNHLGDMTSEEVVQKMTGL-KVPPSHSRSNDTLYIPDWEGRTPDSIDYRK 124
Query: 355 KGYVTPVKNQQQCGSCWSFSATGSLEGQYFRKNNRLISFSEQQLVDCSXXXXXXXXXXXL 534
KGYVTPVKNQ QCGSCW+FS+ G+LEGQ +K +L++ S Q LVDC
Sbjct: 125 KGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDC--VSENDGCGGGY 182
Query: 535 MDNAFRYI-KDQGIESEGDYPYTATDGTCKRNPSKIVTKCTGFTDIQSQNETDLANAVAT 711
M NAF+Y+ K++GI+SE YPY D C NP+ KC G+ +I NE L AVA
Sbjct: 183 MTNAFQYVQKNRGIDSEDAYPYVGQDENCMYNPTGKAAKCRGYREIPEGNEKALKRAVAR 242
Query: 712 VGPVSVAIDAGHASFQLYKSGIYNEESCSTTQLDHGVLAVGYGTQIGKNTGLLK 873
VGPVSVAIDA SFQ Y G+Y +E+C++ L+H VLAVGYG Q GK ++K
Sbjct: 243 VGPVSVAIDASLTSFQFYSKGVYYDENCNSDNLNHAVLAVGYGIQKGKKHWIIK 296
Score = 40.4 bits (93), Expect = 0.007
Identities = 14/24 (58%), Positives = 18/24 (75%)
Frame = +3
Query: 852 KKYWIVKNSWDVTWGESGYIKMSK 923
KK+WI+KNSW WG GYI M++
Sbjct: 290 KKHWIIKNSWGENWGNKGYILMAR 313
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.315 0.132 0.390
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 102,512,741
Number of Sequences: 369166
Number of extensions: 2022739
Number of successful extensions: 6348
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 5479
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5888
length of database: 68,354,980
effective HSP length: 110
effective length of database: 48,034,130
effective search space used: 9462723610
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)