Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_026_A10
(376 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P25782|CYSP2_HOMAM Digestive cysteine proteinase 2 precu... 141 5e-34
sp|Q10991|CATL_SHEEP Cathepsin L [Contains: Cathepsin L hea... 140 9e-34
sp|Q26636|CATL_SARPE Cathepsin L precursor [Contains: Cathe... 140 1e-33
sp|Q95029|CATL_DROME Cathepsin L precursor (Cysteine protei... 139 2e-33
sp|Q9GL24|CATL_CANFA Cathepsin L precursor [Contains: Cathe... 138 4e-33
sp|O60911|CATL2_HUMAN Cathepsin L2 precursor (Cathepsin V) ... 136 1e-32
sp|Q28944|CATL_PIG Cathepsin L precursor [Contains: Catheps... 136 1e-32
sp|P25975|CATL_BOVIN Cathepsin L precursor [Contains: Cathe... 136 1e-32
sp|P25784|CYSP3_HOMAM Digestive cysteine proteinase 3 precu... 136 1e-32
sp|P13277|CYSP1_HOMAM Digestive cysteine proteinase 1 precu... 134 8e-32
>sp|P25782|CYSP2_HOMAM Digestive cysteine proteinase 2 precursor
Length = 323
Score = 141 bits (355), Expect = 5e-34
Identities = 62/101 (61%), Positives = 80/101 (79%)
Frame = +2
Query: 5 SQNETDLANAVATVGPVSVAIDAGHASFQLYKSGIYNEESCSTTQLDHGVLAVGYGTQIG 184
S +ET L AV +GP+SV IDA H+SFQ Y SG+Y E SCS + LDH VLAVGYG++ G
Sbjct: 223 SGSETGLQQAVRDIGPISVTIDAAHSSFQFYSSGVYYEPSCSPSYLDHAVLAVGYGSEGG 282
Query: 185 KKYWIVKNSWDVTWGESGYIKMSKDKKNQCGIATMASYPLV 307
+ +W+VKNSW +WG++GYIKMS+++ N CGIAT+ASYPLV
Sbjct: 283 QDFWLVKNSWATSWGDAGYIKMSRNRNNNCGIATVASYPLV 323
>sp|Q10991|CATL_SHEEP Cathepsin L [Contains: Cathepsin L heavy chain; Cathepsin L light
chain]
Length = 217
Score = 140 bits (353), Expect = 9e-34
Identities = 66/101 (65%), Positives = 75/101 (74%), Gaps = 1/101 (0%)
Frame = +2
Query: 8 QNETDLANAVATVGPVSVAIDAGHASFQLYKSGIYNEESCSTTQLDHGVLAVGYGTQ-IG 184
Q E L AVATVGP+SVAIDAGH+SFQ YKSGIY + CS+ LDHGVL VGYG +
Sbjct: 117 QREKALMKAVATVGPISVAIDAGHSSFQFYKSGIYYDPDCSSKDLDHGVLVVGYGFEGTN 176
Query: 185 KKYWIVKNSWDVTWGESGYIKMSKDKKNQCGIATMASYPLV 307
K+WIVKNSW WG GY+KM+KD+ N CGIAT ASYP V
Sbjct: 177 NKFWIVKNSWGPEWGNKGYVKMAKDQNNHCGIATAASYPTV 217
>sp|Q26636|CATL_SARPE Cathepsin L precursor [Contains: Cathepsin L heavy chain; Cathepsin
L light chain]
Length = 339
Score = 140 bits (352), Expect = 1e-33
Identities = 64/100 (64%), Positives = 75/100 (75%), Gaps = 1/100 (1%)
Frame = +2
Query: 11 NETDLANAVATVGPVSVAIDAGHASFQLYKSGIYNEESCSTTQLDHGVLAVGYGT-QIGK 187
+E + AVAT+GPVSVAIDA H SFQLY G+YNE C LDHGVL VGYGT + G
Sbjct: 240 DEEKMKKAVATMGPVSVAIDASHESFQLYSEGVYNEPECDEQNLDHGVLVVGYGTDESGM 299
Query: 188 KYWIVKNSWDVTWGESGYIKMSKDKKNQCGIATMASYPLV 307
YW+VKNSW TWGE GYIKM++++ NQCGIAT +SYP V
Sbjct: 300 DYWLVKNSWGTTWGEQGYIKMARNQNNQCGIATASSYPTV 339
>sp|Q95029|CATL_DROME Cathepsin L precursor (Cysteine proteinase 1) [Contains: Cathepsin
L heavy chain; Cathepsin L light chain]
Length = 341
Score = 139 bits (351), Expect = 2e-33
Identities = 63/100 (63%), Positives = 77/100 (77%), Gaps = 1/100 (1%)
Frame = +2
Query: 11 NETDLANAVATVGPVSVAIDAGHASFQLYKSGIYNEESCSTTQLDHGVLAVGYGT-QIGK 187
+E +A AVATVGPVSVAIDA H SFQ Y G+YNE C LDHGVL VG+GT + G+
Sbjct: 242 DEKKMAEAVATVGPVSVAIDASHESFQFYSEGVYNEPQCDAQNLDHGVLVVGFGTDESGE 301
Query: 188 KYWIVKNSWDVTWGESGYIKMSKDKKNQCGIATMASYPLV 307
YW+VKNSW TWG+ G+IKM ++K+NQCGIA+ +SYPLV
Sbjct: 302 DYWLVKNSWGTTWGDKGFIKMLRNKENQCGIASASSYPLV 341
>sp|Q9GL24|CATL_CANFA Cathepsin L precursor [Contains: Cathepsin L heavy chain; Cathepsin
L light chain]
Length = 333
Score = 138 bits (347), Expect = 4e-33
Identities = 66/103 (64%), Positives = 75/103 (72%), Gaps = 3/103 (2%)
Frame = +2
Query: 8 QNETDLANAVATVGPVSVAIDAGHASFQLYKSGIYNEESCSTTQLDHGVLAVGY---GTQ 178
Q E L AVAT+GP+SVAIDAGH SFQ YKSGIY + CS+ LDHGVL VGY GT
Sbjct: 231 QREKALMKAVATLGPISVAIDAGHQSFQFYKSGIYFDPDCSSKDLDHGVLVVGYGFEGTD 290
Query: 179 IGKKYWIVKNSWDVTWGESGYIKMSKDKKNQCGIATMASYPLV 307
K+WIVKNSW WG +GY+KM+KD+ N CGIAT ASYP V
Sbjct: 291 SNNKFWIVKNSWGPEWGWNGYVKMAKDQNNHCGIATAASYPTV 333
>sp|O60911|CATL2_HUMAN Cathepsin L2 precursor (Cathepsin V) (Cathepsin U)
Length = 334
Score = 136 bits (343), Expect = 1e-32
Identities = 65/102 (63%), Positives = 74/102 (72%), Gaps = 4/102 (3%)
Frame = +2
Query: 14 ETDLANAVATVGPVSVAIDAGHASFQLYKSGIYNEESCSTTQLDHGVLAVGYG----TQI 181
E L AVATVGP+SVA+DAGH+SFQ YKSGIY E CS+ LDHGVL VGYG
Sbjct: 233 EKALMKAVATVGPISVAMDAGHSSFQFYKSGIYFEPDCSSKNLDHGVLVVGYGFEGANSN 292
Query: 182 GKKYWIVKNSWDVTWGESGYIKMSKDKKNQCGIATMASYPLV 307
KYW+VKNSW WG +GY+K++KDK N CGIAT ASYP V
Sbjct: 293 NSKYWLVKNSWGPEWGSNGYVKIAKDKNNHCGIATAASYPNV 334
>sp|Q28944|CATL_PIG Cathepsin L precursor [Contains: Cathepsin L heavy chain; Cathepsin
L light chain]
Length = 334
Score = 136 bits (343), Expect = 1e-32
Identities = 65/104 (62%), Positives = 76/104 (73%), Gaps = 4/104 (3%)
Frame = +2
Query: 8 QNETDLANAVATVGPVSVAIDAGHASFQLYKSGIYNEESCSTTQLDHGVLAVGYGTQ--- 178
Q E L AVATVGP+SVAIDAGH+SFQ YKSGIY + CS+ LDHGVL VGYG +
Sbjct: 231 QREKALMKAVATVGPISVAIDAGHSSFQFYKSGIYYDPDCSSKDLDHGVLVVGYGFEGTD 290
Query: 179 -IGKKYWIVKNSWDVTWGESGYIKMSKDKKNQCGIATMASYPLV 307
K+WIVKNSW WG +GY+KM+KD+ N CGI+T ASYP V
Sbjct: 291 SNSSKFWIVKNSWGPEWGWNGYVKMAKDQNNHCGISTAASYPTV 334
>sp|P25975|CATL_BOVIN Cathepsin L precursor [Contains: Cathepsin L heavy chain; Cathepsin
L light chain]
Length = 334
Score = 136 bits (343), Expect = 1e-32
Identities = 66/104 (63%), Positives = 74/104 (71%), Gaps = 4/104 (3%)
Frame = +2
Query: 8 QNETDLANAVATVGPVSVAIDAGHASFQLYKSGIYNEESCSTTQLDHGVLAVGYGTQ--- 178
Q E L AVATVGP+SVAIDAGH SFQ YKSGIY + CS LDHGVL VGYG +
Sbjct: 231 QREKALMKAVATVGPISVAIDAGHTSFQFYKSGIYYDPDCSCKDLDHGVLVVGYGFEGTD 290
Query: 179 -IGKKYWIVKNSWDVTWGESGYIKMSKDKKNQCGIATMASYPLV 307
K+WIVKNSW WG +GY+KM+KD+ N CGIAT ASYP V
Sbjct: 291 SNNNKFWIVKNSWGPEWGWNGYVKMAKDQNNHCGIATAASYPTV 334
>sp|P25784|CYSP3_HOMAM Digestive cysteine proteinase 3 precursor
Length = 321
Score = 136 bits (343), Expect = 1e-32
Identities = 62/98 (63%), Positives = 76/98 (77%)
Frame = +2
Query: 14 ETDLANAVATVGPVSVAIDAGHASFQLYKSGIYNEESCSTTQLDHGVLAVGYGTQIGKKY 193
E L AV+ VGP+SVAIDA H SFQ Y SG+Y E++CS T LDHGVLAVGYGT+ K Y
Sbjct: 224 EEALQEAVSGVGPISVAIDASHFSFQFYSSGVYYEQNCSPTFLDHGVLAVGYGTESTKDY 283
Query: 194 WIVKNSWDVTWGESGYIKMSKDKKNQCGIATMASYPLV 307
W+VKNSW +WG++GYIKMS+++ N CGIA+ SYP V
Sbjct: 284 WLVKNSWGSSWGDAGYIKMSRNRDNNCGIASEPSYPTV 321
>sp|P13277|CYSP1_HOMAM Digestive cysteine proteinase 1 precursor
Length = 322
Score = 134 bits (336), Expect = 8e-32
Identities = 59/99 (59%), Positives = 77/99 (77%)
Frame = +2
Query: 11 NETDLANAVATVGPVSVAIDAGHASFQLYKSGIYNEESCSTTQLDHGVLAVGYGTQIGKK 190
+E+ L A +GP+SVAIDA H SFQ Y +G+Y E SCS++QLDH VLAVGYG++ G+
Sbjct: 224 SESALKTATRDIGPISVAIDASHRSFQSYYTGVYYEPSCSSSQLDHAVLAVGYGSEGGQD 283
Query: 191 YWIVKNSWDVTWGESGYIKMSKDKKNQCGIATMASYPLV 307
+W+VKNSW +WGESGYIKM++++ N CGIAT A YP V
Sbjct: 284 FWLVKNSWATSWGESGYIKMARNRNNNCGIATDACYPTV 322
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 44,161,995
Number of Sequences: 369166
Number of extensions: 857818
Number of successful extensions: 2813
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 2587
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 2635
length of database: 68,354,980
effective HSP length: 91
effective length of database: 51,544,095
effective search space used: 1700955135
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)