Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= Dr_sW_014_J02 (322 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|P25782|CYSP2_HOMAM Digestive cysteine proteinase 2 precu... 125 2e-29 sp|Q26636|CATL_SARPE Cathepsin L precursor [Contains: Cathe... 124 5e-29 sp|P25784|CYSP3_HOMAM Digestive cysteine proteinase 3 precu... 124 7e-29 sp|P13277|CYSP1_HOMAM Digestive cysteine proteinase 1 precu... 122 2e-28 sp|Q10991|CATL_SHEEP Cathepsin L [Contains: Cathepsin L hea... 122 3e-28 sp|Q95029|CATL_DROME Cathepsin L precursor (Cysteine protei... 121 6e-28 sp|Q9GL24|CATL_CANFA Cathepsin L precursor [Contains: Cathe... 121 6e-28 sp|O60911|CATL2_HUMAN Cathepsin L2 precursor (Cathepsin V) ... 120 1e-27 sp|Q28944|CATL_PIG Cathepsin L precursor [Contains: Catheps... 118 4e-27 sp|P25975|CATL_BOVIN Cathepsin L precursor [Contains: Cathe... 118 4e-27
>sp|P25782|CYSP2_HOMAM Digestive cysteine proteinase 2 precursor Length = 323 Score = 125 bits (315), Expect = 2e-29 Identities = 54/84 (64%), Positives = 69/84 (82%) Frame = +2 Query: 2 SVAIDAGHASFQLYKSGIYNEESCSTTQLDHGVLAVGYGTQIGKKYWIVKNSWDVTWGES 181 SV IDA H+SFQ Y SG+Y E SCS + LDH VLAVGYG++ G+ +W+VKNSW +WG++ Sbjct: 240 SVTIDAAHSSFQFYSSGVYYEPSCSPSYLDHAVLAVGYGSEGGQDFWLVKNSWATSWGDA 299 Query: 182 GYIKMSKDKKNQCGIATMASYPLV 253 GYIKMS+++ N CGIAT+ASYPLV Sbjct: 300 GYIKMSRNRNNNCGIATVASYPLV 323
>sp|Q26636|CATL_SARPE Cathepsin L precursor [Contains: Cathepsin L heavy chain; Cathepsin L light chain] Length = 339 Score = 124 bits (312), Expect = 5e-29 Identities = 56/85 (65%), Positives = 64/85 (75%), Gaps = 1/85 (1%) Frame = +2 Query: 2 SVAIDAGHASFQLYKSGIYNEESCSTTQLDHGVLAVGYGT-QIGKKYWIVKNSWDVTWGE 178 SVAIDA H SFQLY G+YNE C LDHGVL VGYGT + G YW+VKNSW TWGE Sbjct: 255 SVAIDASHESFQLYSEGVYNEPECDEQNLDHGVLVVGYGTDESGMDYWLVKNSWGTTWGE 314 Query: 179 SGYIKMSKDKKNQCGIATMASYPLV 253 GYIKM++++ NQCGIAT +SYP V Sbjct: 315 QGYIKMARNQNNQCGIATASSYPTV 339
>sp|P25784|CYSP3_HOMAM Digestive cysteine proteinase 3 precursor Length = 321 Score = 124 bits (311), Expect = 7e-29 Identities = 55/84 (65%), Positives = 67/84 (79%) Frame = +2 Query: 2 SVAIDAGHASFQLYKSGIYNEESCSTTQLDHGVLAVGYGTQIGKKYWIVKNSWDVTWGES 181 SVAIDA H SFQ Y SG+Y E++CS T LDHGVLAVGYGT+ K YW+VKNSW +WG++ Sbjct: 238 SVAIDASHFSFQFYSSGVYYEQNCSPTFLDHGVLAVGYGTESTKDYWLVKNSWGSSWGDA 297 Query: 182 GYIKMSKDKKNQCGIATMASYPLV 253 GYIKMS+++ N CGIA+ SYP V Sbjct: 298 GYIKMSRNRDNNCGIASEPSYPTV 321
>sp|P13277|CYSP1_HOMAM Digestive cysteine proteinase 1 precursor Length = 322 Score = 122 bits (307), Expect = 2e-28 Identities = 54/84 (64%), Positives = 68/84 (80%) Frame = +2 Query: 2 SVAIDAGHASFQLYKSGIYNEESCSTTQLDHGVLAVGYGTQIGKKYWIVKNSWDVTWGES 181 SVAIDA H SFQ Y +G+Y E SCS++QLDH VLAVGYG++ G+ +W+VKNSW +WGES Sbjct: 239 SVAIDASHRSFQSYYTGVYYEPSCSSSQLDHAVLAVGYGSEGGQDFWLVKNSWATSWGES 298 Query: 182 GYIKMSKDKKNQCGIATMASYPLV 253 GYIKM++++ N CGIAT A YP V Sbjct: 299 GYIKMARNRNNNCGIATDACYPTV 322
>sp|Q10991|CATL_SHEEP Cathepsin L [Contains: Cathepsin L heavy chain; Cathepsin L light chain] Length = 217 Score = 122 bits (306), Expect = 3e-28 Identities = 56/85 (65%), Positives = 64/85 (75%), Gaps = 1/85 (1%) Frame = +2 Query: 2 SVAIDAGHASFQLYKSGIYNEESCSTTQLDHGVLAVGYGTQ-IGKKYWIVKNSWDVTWGE 178 SVAIDAGH+SFQ YKSGIY + CS+ LDHGVL VGYG + K+WIVKNSW WG Sbjct: 133 SVAIDAGHSSFQFYKSGIYYDPDCSSKDLDHGVLVVGYGFEGTNNKFWIVKNSWGPEWGN 192 Query: 179 SGYIKMSKDKKNQCGIATMASYPLV 253 GY+KM+KD+ N CGIAT ASYP V Sbjct: 193 KGYVKMAKDQNNHCGIATAASYPTV 217
>sp|Q95029|CATL_DROME Cathepsin L precursor (Cysteine proteinase 1) [Contains: Cathepsin L heavy chain; Cathepsin L light chain] Length = 341 Score = 121 bits (303), Expect = 6e-28 Identities = 53/85 (62%), Positives = 65/85 (76%), Gaps = 1/85 (1%) Frame = +2 Query: 2 SVAIDAGHASFQLYKSGIYNEESCSTTQLDHGVLAVGYGT-QIGKKYWIVKNSWDVTWGE 178 SVAIDA H SFQ Y G+YNE C LDHGVL VG+GT + G+ YW+VKNSW TWG+ Sbjct: 257 SVAIDASHESFQFYSEGVYNEPQCDAQNLDHGVLVVGFGTDESGEDYWLVKNSWGTTWGD 316 Query: 179 SGYIKMSKDKKNQCGIATMASYPLV 253 G+IKM ++K+NQCGIA+ +SYPLV Sbjct: 317 KGFIKMLRNKENQCGIASASSYPLV 341
>sp|Q9GL24|CATL_CANFA Cathepsin L precursor [Contains: Cathepsin L heavy chain; Cathepsin L light chain] Length = 333 Score = 121 bits (303), Expect = 6e-28 Identities = 57/87 (65%), Positives = 64/87 (73%), Gaps = 3/87 (3%) Frame = +2 Query: 2 SVAIDAGHASFQLYKSGIYNEESCSTTQLDHGVLAVGYG---TQIGKKYWIVKNSWDVTW 172 SVAIDAGH SFQ YKSGIY + CS+ LDHGVL VGYG T K+WIVKNSW W Sbjct: 247 SVAIDAGHQSFQFYKSGIYFDPDCSSKDLDHGVLVVGYGFEGTDSNNKFWIVKNSWGPEW 306 Query: 173 GESGYIKMSKDKKNQCGIATMASYPLV 253 G +GY+KM+KD+ N CGIAT ASYP V Sbjct: 307 GWNGYVKMAKDQNNHCGIATAASYPTV 333
>sp|O60911|CATL2_HUMAN Cathepsin L2 precursor (Cathepsin V) (Cathepsin U) Length = 334 Score = 120 bits (301), Expect = 1e-27 Identities = 56/88 (63%), Positives = 65/88 (73%), Gaps = 4/88 (4%) Frame = +2 Query: 2 SVAIDAGHASFQLYKSGIYNEESCSTTQLDHGVLAVGYGTQ----IGKKYWIVKNSWDVT 169 SVA+DAGH+SFQ YKSGIY E CS+ LDHGVL VGYG + KYW+VKNSW Sbjct: 247 SVAMDAGHSSFQFYKSGIYFEPDCSSKNLDHGVLVVGYGFEGANSNNSKYWLVKNSWGPE 306 Query: 170 WGESGYIKMSKDKKNQCGIATMASYPLV 253 WG +GY+K++KDK N CGIAT ASYP V Sbjct: 307 WGSNGYVKIAKDKNNHCGIATAASYPNV 334
>sp|Q28944|CATL_PIG Cathepsin L precursor [Contains: Cathepsin L heavy chain; Cathepsin L light chain] Length = 334 Score = 118 bits (296), Expect = 4e-27 Identities = 55/88 (62%), Positives = 65/88 (73%), Gaps = 4/88 (4%) Frame = +2 Query: 2 SVAIDAGHASFQLYKSGIYNEESCSTTQLDHGVLAVGYGTQ----IGKKYWIVKNSWDVT 169 SVAIDAGH+SFQ YKSGIY + CS+ LDHGVL VGYG + K+WIVKNSW Sbjct: 247 SVAIDAGHSSFQFYKSGIYYDPDCSSKDLDHGVLVVGYGFEGTDSNSSKFWIVKNSWGPE 306 Query: 170 WGESGYIKMSKDKKNQCGIATMASYPLV 253 WG +GY+KM+KD+ N CGI+T ASYP V Sbjct: 307 WGWNGYVKMAKDQNNHCGISTAASYPTV 334
>sp|P25975|CATL_BOVIN Cathepsin L precursor [Contains: Cathepsin L heavy chain; Cathepsin L light chain] Length = 334 Score = 118 bits (296), Expect = 4e-27 Identities = 56/88 (63%), Positives = 63/88 (71%), Gaps = 4/88 (4%) Frame = +2 Query: 2 SVAIDAGHASFQLYKSGIYNEESCSTTQLDHGVLAVGYGTQ----IGKKYWIVKNSWDVT 169 SVAIDAGH SFQ YKSGIY + CS LDHGVL VGYG + K+WIVKNSW Sbjct: 247 SVAIDAGHTSFQFYKSGIYYDPDCSCKDLDHGVLVVGYGFEGTDSNNNKFWIVKNSWGPE 306 Query: 170 WGESGYIKMSKDKKNQCGIATMASYPLV 253 WG +GY+KM+KD+ N CGIAT ASYP V Sbjct: 307 WGWNGYVKMAKDQNNHCGIATAASYPTV 334
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 38,596,796 Number of Sequences: 369166 Number of extensions: 756593 Number of successful extensions: 2443 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 2262 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 2301 length of database: 68,354,980 effective HSP length: 75 effective length of database: 54,499,855 effective search space used: 1689495505 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)