Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_028_K13
(268 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P07711|CATL_HUMAN Cathepsin L precursor (Major excreted ... 118 5e-27
sp|P25975|CATL_BOVIN Cathepsin L precursor [Contains: Cathe... 118 5e-27
sp|Q10991|CATL_SHEEP Cathepsin L [Contains: Cathepsin L hea... 115 2e-26
sp|Q9GL24|CATL_CANFA Cathepsin L precursor [Contains: Cathe... 115 3e-26
sp|O60911|CATL2_HUMAN Cathepsin L2 precursor (Cathepsin V) ... 113 2e-25
sp|P06797|CATL_MOUSE Cathepsin L precursor (Major excreted ... 110 8e-25
sp|P07154|CATL_RAT Cathepsin L precursor (Major excreted pr... 110 8e-25
sp||P09648_1 [Segment 1 of 2] Cathepsin L [Contains: Cathep... 110 1e-24
sp|Q24940|CATLP_FASHE Cathepsin L-like proteinase precursor 109 2e-24
sp|Q95029|CATL_DROME Cathepsin L precursor (Cysteine protei... 108 4e-24
>sp|P07711|CATL_HUMAN Cathepsin L precursor (Major excreted protein) (MEP) [Contains:
Cathepsin L heavy chain; Cathepsin L light chain]
Length = 333
Score = 118 bits (295), Expect = 5e-27
Identities = 57/90 (63%), Positives = 66/90 (73%), Gaps = 1/90 (1%)
Frame = +1
Query: 1 KGYVTPVKNQQQCGSCWSFSATGSLEGQYFRKNNRLISFSEQQLVDCSXXXXXXXXXXXL 180
KGYVTPVKNQ QCGSCW+FSATG+LEGQ FRK RLIS SEQ LVDCS L
Sbjct: 123 KGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNGGL 182
Query: 181 MDNAFRYIKDQ-GIESEGDYPYTATDGTCK 267
MD AF+Y++D G++SE YPY AT+ +CK
Sbjct: 183 MDYAFQYVQDNGGLDSEESYPYEATEESCK 212
>sp|P25975|CATL_BOVIN Cathepsin L precursor [Contains: Cathepsin L heavy chain; Cathepsin
L light chain]
Length = 334
Score = 118 bits (295), Expect = 5e-27
Identities = 57/86 (66%), Positives = 64/86 (74%), Gaps = 1/86 (1%)
Frame = +1
Query: 1 KGYVTPVKNQQQCGSCWSFSATGSLEGQYFRKNNRLISFSEQQLVDCSXXXXXXXXXXXL 180
KGYVTPVKNQ QCGSCW+FSATG+LEGQ FRK +L+S SEQ LVDCS L
Sbjct: 123 KGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSRAQGNQGCNGGL 182
Query: 181 MDNAFRYIKDQ-GIESEGDYPYTATD 255
MDNAF+YIKD G++SE YPY ATD
Sbjct: 183 MDNAFQYIKDNGGLDSEESYPYLATD 208
>sp|Q10991|CATL_SHEEP Cathepsin L [Contains: Cathepsin L heavy chain; Cathepsin L light
chain]
Length = 217
Score = 115 bits (289), Expect = 2e-26
Identities = 56/89 (62%), Positives = 65/89 (73%), Gaps = 1/89 (1%)
Frame = +1
Query: 1 KGYVTPVKNQQQCGSCWSFSATGSLEGQYFRKNNRLISFSEQQLVDCSXXXXXXXXXXXL 180
KGYVTPVKNQ QCGSCW+FSATG+LEGQ FRK +L+S SEQ LVD S L
Sbjct: 10 KGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDSSRPQGNQGCNGGL 69
Query: 181 MDNAFRYIKDQ-GIESEGDYPYTATDGTC 264
MDNAF+YIK+ G++SE YPY ATD +C
Sbjct: 70 MDNAFQYIKENGGLDSEESYPYEATDTSC 98
>sp|Q9GL24|CATL_CANFA Cathepsin L precursor [Contains: Cathepsin L heavy chain; Cathepsin
L light chain]
Length = 333
Score = 115 bits (288), Expect = 3e-26
Identities = 55/86 (63%), Positives = 62/86 (72%), Gaps = 1/86 (1%)
Frame = +1
Query: 1 KGYVTPVKNQQQCGSCWSFSATGSLEGQYFRKNNRLISFSEQQLVDCSXXXXXXXXXXXL 180
KGYVTPVKNQ QCGSCW+FSATG+LEGQ FRK +L+S SEQ LVDCS L
Sbjct: 123 KGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSRAQGNEGCNGGL 182
Query: 181 MDNAFRYIKDQ-GIESEGDYPYTATD 255
MDNAFRY+KD G++SE YPY D
Sbjct: 183 MDNAFRYVKDNGGLDSEESYPYLGRD 208
>sp|O60911|CATL2_HUMAN Cathepsin L2 precursor (Cathepsin V) (Cathepsin U)
Length = 334
Score = 113 bits (282), Expect = 2e-25
Identities = 53/90 (58%), Positives = 63/90 (70%), Gaps = 1/90 (1%)
Frame = +1
Query: 1 KGYVTPVKNQQQCGSCWSFSATGSLEGQYFRKNNRLISFSEQQLVDCSXXXXXXXXXXXL 180
KGYVTPVKNQ+QCGSCW+FSATG+LEGQ FRK +L+S SEQ LVDCS
Sbjct: 123 KGYVTPVKNQKQCGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSRPQGNQGCNGGF 182
Query: 181 MDNAFRYIKDQ-GIESEGDYPYTATDGTCK 267
M AF+Y+K+ G++SE YPY A D CK
Sbjct: 183 MARAFQYVKENGGLDSEESYPYVAVDEICK 212
>sp|P06797|CATL_MOUSE Cathepsin L precursor (Major excreted protein) (MEP) (p39 cysteine
proteinase) [Contains: Cathepsin L heavy chain;
Cathepsin L light chain]
Length = 334
Score = 110 bits (276), Expect = 8e-25
Identities = 55/90 (61%), Positives = 63/90 (70%), Gaps = 1/90 (1%)
Frame = +1
Query: 1 KGYVTPVKNQQQCGSCWSFSATGSLEGQYFRKNNRLISFSEQQLVDCSXXXXXXXXXXXL 180
KG VTPVKNQ QCGSCW+FSA+G LEGQ F K +LIS SEQ LVDCS L
Sbjct: 123 KGCVTPVKNQGQCGSCWAFSASGCLEGQMFLKTGKLISLSEQNLVDCSHAQGNQGCNGGL 182
Query: 181 MDNAFRYIKDQ-GIESEGDYPYTATDGTCK 267
MD AF+YIK+ G++SE YPY A DG+CK
Sbjct: 183 MDFAFQYIKENGGLDSEESYPYEAKDGSCK 212
>sp|P07154|CATL_RAT Cathepsin L precursor (Major excreted protein) (MEP) (Cyclic
protein 2) (CP-2) [Contains: Cathepsin L heavy chain;
Cathepsin L light chain]
Length = 334
Score = 110 bits (276), Expect = 8e-25
Identities = 55/90 (61%), Positives = 63/90 (70%), Gaps = 1/90 (1%)
Frame = +1
Query: 1 KGYVTPVKNQQQCGSCWSFSATGSLEGQYFRKNNRLISFSEQQLVDCSXXXXXXXXXXXL 180
KG VTPVKNQ QCGSCW+FSA+G LEGQ F K +LIS SEQ LVDCS L
Sbjct: 123 KGCVTPVKNQGQCGSCWAFSASGCLEGQMFLKTGKLISLSEQNLVDCSHDQGNQGCNGGL 182
Query: 181 MDNAFRYIKDQ-GIESEGDYPYTATDGTCK 267
MD AF+YIK+ G++SE YPY A DG+CK
Sbjct: 183 MDFAFQYIKENGGLDSEESYPYEAKDGSCK 212
>sp||P09648_1 [Segment 1 of 2] Cathepsin L [Contains: Cathepsin L heavy chain;
Cathepsin L light chain]
Length = 176
Score = 110 bits (274), Expect = 1e-24
Identities = 52/86 (60%), Positives = 62/86 (72%), Gaps = 1/86 (1%)
Frame = +1
Query: 1 KGYVTPVKNQQQCGSCWSFSATGSLEGQYFRKNNRLISFSEQQLVDCSXXXXXXXXXXXL 180
KGYVTPVK+Q QCGSCW+FS TG+LEGQ+FR +L+S SEQ LVDCS L
Sbjct: 10 KGYVTPVKDQGQCGSCWAFSTTGALEGQHFRTKGKLVSLSEQNLVDCSRPEGNQGCNGGL 69
Query: 181 MDNAFRYIKDQ-GIESEGDYPYTATD 255
MD AF+Y++D GI+SE YPYTA D
Sbjct: 70 MDQAFQYVQDNGGIDSEESYPYTAKD 95
>sp|Q24940|CATLP_FASHE Cathepsin L-like proteinase precursor
Length = 326
Score = 109 bits (272), Expect = 2e-24
Identities = 48/88 (54%), Positives = 61/88 (69%)
Frame = +1
Query: 4 GYVTPVKNQQQCGSCWSFSATGSLEGQYFRKNNRLISFSEQQLVDCSXXXXXXXXXXXLM 183
GYVT VK+Q CGSCW+FS TG++EGQY + ISFSEQQLVDCS LM
Sbjct: 118 GYVTEVKDQGNCGSCWAFSTTGTMEGQYMKNERTSISFSEQQLVDCSGPWGNNGCSGGLM 177
Query: 184 DNAFRYIKDQGIESEGDYPYTATDGTCK 267
+NA++Y+K G+E+E YPYTA +G C+
Sbjct: 178 ENAYQYLKQFGLETESSYPYTAVEGQCR 205
>sp|Q95029|CATL_DROME Cathepsin L precursor (Cysteine proteinase 1) [Contains: Cathepsin
L heavy chain; Cathepsin L light chain]
Length = 341
Score = 108 bits (270), Expect = 4e-24
Identities = 53/89 (59%), Positives = 63/89 (70%), Gaps = 1/89 (1%)
Frame = +1
Query: 1 KGYVTPVKNQQQCGSCWSFSATGSLEGQYFRKNNRLISFSEQQLVDCSXXXXXXXXXXXL 180
KG VT VK+Q CGSCW+FS+TG+LEGQ+FRK+ L+S SEQ LVDCS L
Sbjct: 133 KGAVTAVKDQGHCGSCWAFSSTGALEGQHFRKSGVLVSLSEQNLVDCSTKYGNNGCNGGL 192
Query: 181 MDNAFRYIKDQ-GIESEGDYPYTATDGTC 264
MDNAFRYIKD GI++E YPY A D +C
Sbjct: 193 MDNAFRYIKDNGGIDTEKSYPYEAIDDSC 221
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.316 0.132 0.410
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 24,171,278
Number of Sequences: 369166
Number of extensions: 292654
Number of successful extensions: 1217
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 1084
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 1088
length of database: 68,354,980
effective HSP length: 58
effective length of database: 57,640,350
effective search space used: 1729210500
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)