Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= Dr_sW_008_B10 (368 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|P25782|CYSP2_HOMAM Digestive cysteine proteinase 2 precu... 140 9e-34 sp|Q26636|CATL_SARPE Cathepsin L precursor [Contains: Cathe... 140 1e-33 sp|Q95029|CATL_DROME Cathepsin L precursor (Cysteine protei... 139 2e-33 sp|Q10991|CATL_SHEEP Cathepsin L [Contains: Cathepsin L hea... 138 3e-33 sp|O60911|CATL2_HUMAN Cathepsin L2 precursor (Cathepsin V) ... 136 1e-32 sp|P25784|CYSP3_HOMAM Digestive cysteine proteinase 3 precu... 136 1e-32 sp|Q9GL24|CATL_CANFA Cathepsin L precursor [Contains: Cathe... 136 2e-32 sp|Q28944|CATL_PIG Cathepsin L precursor [Contains: Catheps... 134 5e-32 sp|P25975|CATL_BOVIN Cathepsin L precursor [Contains: Cathe... 134 5e-32 sp|P13277|CYSP1_HOMAM Digestive cysteine proteinase 1 precu... 134 9e-32
>sp|P25782|CYSP2_HOMAM Digestive cysteine proteinase 2 precursor Length = 323 Score = 140 bits (353), Expect = 9e-34 Identities = 61/99 (61%), Positives = 79/99 (79%) Frame = +3 Query: 3 NETDLANAVATVGPVSVAIDAGHASFQLYKSGIYNEESCSTTQLDHGVLAVGYGTQIGKK 182 +ET L AV +GP+SV IDA H+SFQ Y SG+Y E SCS + LDH VLAVGYG++ G+ Sbjct: 225 SETGLQQAVRDIGPISVTIDAAHSSFQFYSSGVYYEPSCSPSYLDHAVLAVGYGSEGGQD 284 Query: 183 YWIVKNSWDVTWGESGYIKMSKDKKNQCGIATMASYPLV 299 +W+VKNSW +WG++GYIKMS+++ N CGIAT+ASYPLV Sbjct: 285 FWLVKNSWATSWGDAGYIKMSRNRNNNCGIATVASYPLV 323
>sp|Q26636|CATL_SARPE Cathepsin L precursor [Contains: Cathepsin L heavy chain; Cathepsin L light chain] Length = 339 Score = 140 bits (352), Expect = 1e-33 Identities = 64/100 (64%), Positives = 75/100 (75%), Gaps = 1/100 (1%) Frame = +3 Query: 3 NETDLANAVATVGPVSVAIDAGHASFQLYKSGIYNEESCSTTQLDHGVLAVGYGT-QIGK 179 +E + AVAT+GPVSVAIDA H SFQLY G+YNE C LDHGVL VGYGT + G Sbjct: 240 DEEKMKKAVATMGPVSVAIDASHESFQLYSEGVYNEPECDEQNLDHGVLVVGYGTDESGM 299 Query: 180 KYWIVKNSWDVTWGESGYIKMSKDKKNQCGIATMASYPLV 299 YW+VKNSW TWGE GYIKM++++ NQCGIAT +SYP V Sbjct: 300 DYWLVKNSWGTTWGEQGYIKMARNQNNQCGIATASSYPTV 339
>sp|Q95029|CATL_DROME Cathepsin L precursor (Cysteine proteinase 1) [Contains: Cathepsin L heavy chain; Cathepsin L light chain] Length = 341 Score = 139 bits (351), Expect = 2e-33 Identities = 63/100 (63%), Positives = 77/100 (77%), Gaps = 1/100 (1%) Frame = +3 Query: 3 NETDLANAVATVGPVSVAIDAGHASFQLYKSGIYNEESCSTTQLDHGVLAVGYGT-QIGK 179 +E +A AVATVGPVSVAIDA H SFQ Y G+YNE C LDHGVL VG+GT + G+ Sbjct: 242 DEKKMAEAVATVGPVSVAIDASHESFQFYSEGVYNEPQCDAQNLDHGVLVVGFGTDESGE 301 Query: 180 KYWIVKNSWDVTWGESGYIKMSKDKKNQCGIATMASYPLV 299 YW+VKNSW TWG+ G+IKM ++K+NQCGIA+ +SYPLV Sbjct: 302 DYWLVKNSWGTTWGDKGFIKMLRNKENQCGIASASSYPLV 341
>sp|Q10991|CATL_SHEEP Cathepsin L [Contains: Cathepsin L heavy chain; Cathepsin L light chain] Length = 217 Score = 138 bits (348), Expect = 3e-33 Identities = 65/99 (65%), Positives = 74/99 (74%), Gaps = 1/99 (1%) Frame = +3 Query: 6 ETDLANAVATVGPVSVAIDAGHASFQLYKSGIYNEESCSTTQLDHGVLAVGYGTQ-IGKK 182 E L AVATVGP+SVAIDAGH+SFQ YKSGIY + CS+ LDHGVL VGYG + K Sbjct: 119 EKALMKAVATVGPISVAIDAGHSSFQFYKSGIYYDPDCSSKDLDHGVLVVGYGFEGTNNK 178 Query: 183 YWIVKNSWDVTWGESGYIKMSKDKKNQCGIATMASYPLV 299 +WIVKNSW WG GY+KM+KD+ N CGIAT ASYP V Sbjct: 179 FWIVKNSWGPEWGNKGYVKMAKDQNNHCGIATAASYPTV 217
>sp|O60911|CATL2_HUMAN Cathepsin L2 precursor (Cathepsin V) (Cathepsin U) Length = 334 Score = 136 bits (343), Expect = 1e-32 Identities = 65/102 (63%), Positives = 74/102 (72%), Gaps = 4/102 (3%) Frame = +3 Query: 6 ETDLANAVATVGPVSVAIDAGHASFQLYKSGIYNEESCSTTQLDHGVLAVGYG----TQI 173 E L AVATVGP+SVA+DAGH+SFQ YKSGIY E CS+ LDHGVL VGYG Sbjct: 233 EKALMKAVATVGPISVAMDAGHSSFQFYKSGIYFEPDCSSKNLDHGVLVVGYGFEGANSN 292 Query: 174 GKKYWIVKNSWDVTWGESGYIKMSKDKKNQCGIATMASYPLV 299 KYW+VKNSW WG +GY+K++KDK N CGIAT ASYP V Sbjct: 293 NSKYWLVKNSWGPEWGSNGYVKIAKDKNNHCGIATAASYPNV 334
>sp|P25784|CYSP3_HOMAM Digestive cysteine proteinase 3 precursor Length = 321 Score = 136 bits (343), Expect = 1e-32 Identities = 62/98 (63%), Positives = 76/98 (77%) Frame = +3 Query: 6 ETDLANAVATVGPVSVAIDAGHASFQLYKSGIYNEESCSTTQLDHGVLAVGYGTQIGKKY 185 E L AV+ VGP+SVAIDA H SFQ Y SG+Y E++CS T LDHGVLAVGYGT+ K Y Sbjct: 224 EEALQEAVSGVGPISVAIDASHFSFQFYSSGVYYEQNCSPTFLDHGVLAVGYGTESTKDY 283 Query: 186 WIVKNSWDVTWGESGYIKMSKDKKNQCGIATMASYPLV 299 W+VKNSW +WG++GYIKMS+++ N CGIA+ SYP V Sbjct: 284 WLVKNSWGSSWGDAGYIKMSRNRDNNCGIASEPSYPTV 321
>sp|Q9GL24|CATL_CANFA Cathepsin L precursor [Contains: Cathepsin L heavy chain; Cathepsin L light chain] Length = 333 Score = 136 bits (342), Expect = 2e-32 Identities = 65/101 (64%), Positives = 74/101 (73%), Gaps = 3/101 (2%) Frame = +3 Query: 6 ETDLANAVATVGPVSVAIDAGHASFQLYKSGIYNEESCSTTQLDHGVLAVGY---GTQIG 176 E L AVAT+GP+SVAIDAGH SFQ YKSGIY + CS+ LDHGVL VGY GT Sbjct: 233 EKALMKAVATLGPISVAIDAGHQSFQFYKSGIYFDPDCSSKDLDHGVLVVGYGFEGTDSN 292 Query: 177 KKYWIVKNSWDVTWGESGYIKMSKDKKNQCGIATMASYPLV 299 K+WIVKNSW WG +GY+KM+KD+ N CGIAT ASYP V Sbjct: 293 NKFWIVKNSWGPEWGWNGYVKMAKDQNNHCGIATAASYPTV 333
>sp|Q28944|CATL_PIG Cathepsin L precursor [Contains: Cathepsin L heavy chain; Cathepsin L light chain] Length = 334 Score = 134 bits (338), Expect = 5e-32 Identities = 64/102 (62%), Positives = 75/102 (73%), Gaps = 4/102 (3%) Frame = +3 Query: 6 ETDLANAVATVGPVSVAIDAGHASFQLYKSGIYNEESCSTTQLDHGVLAVGYGTQ----I 173 E L AVATVGP+SVAIDAGH+SFQ YKSGIY + CS+ LDHGVL VGYG + Sbjct: 233 EKALMKAVATVGPISVAIDAGHSSFQFYKSGIYYDPDCSSKDLDHGVLVVGYGFEGTDSN 292 Query: 174 GKKYWIVKNSWDVTWGESGYIKMSKDKKNQCGIATMASYPLV 299 K+WIVKNSW WG +GY+KM+KD+ N CGI+T ASYP V Sbjct: 293 SSKFWIVKNSWGPEWGWNGYVKMAKDQNNHCGISTAASYPTV 334
>sp|P25975|CATL_BOVIN Cathepsin L precursor [Contains: Cathepsin L heavy chain; Cathepsin L light chain] Length = 334 Score = 134 bits (338), Expect = 5e-32 Identities = 65/102 (63%), Positives = 73/102 (71%), Gaps = 4/102 (3%) Frame = +3 Query: 6 ETDLANAVATVGPVSVAIDAGHASFQLYKSGIYNEESCSTTQLDHGVLAVGYGTQ----I 173 E L AVATVGP+SVAIDAGH SFQ YKSGIY + CS LDHGVL VGYG + Sbjct: 233 EKALMKAVATVGPISVAIDAGHTSFQFYKSGIYYDPDCSCKDLDHGVLVVGYGFEGTDSN 292 Query: 174 GKKYWIVKNSWDVTWGESGYIKMSKDKKNQCGIATMASYPLV 299 K+WIVKNSW WG +GY+KM+KD+ N CGIAT ASYP V Sbjct: 293 NNKFWIVKNSWGPEWGWNGYVKMAKDQNNHCGIATAASYPTV 334
>sp|P13277|CYSP1_HOMAM Digestive cysteine proteinase 1 precursor Length = 322 Score = 134 bits (336), Expect = 9e-32 Identities = 59/99 (59%), Positives = 77/99 (77%) Frame = +3 Query: 3 NETDLANAVATVGPVSVAIDAGHASFQLYKSGIYNEESCSTTQLDHGVLAVGYGTQIGKK 182 +E+ L A +GP+SVAIDA H SFQ Y +G+Y E SCS++QLDH VLAVGYG++ G+ Sbjct: 224 SESALKTATRDIGPISVAIDASHRSFQSYYTGVYYEPSCSSSQLDHAVLAVGYGSEGGQD 283 Query: 183 YWIVKNSWDVTWGESGYIKMSKDKKNQCGIATMASYPLV 299 +W+VKNSW +WGESGYIKM++++ N CGIAT A YP V Sbjct: 284 FWLVKNSWATSWGESGYIKMARNRNNNCGIATDACYPTV 322
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 43,414,633 Number of Sequences: 369166 Number of extensions: 845245 Number of successful extensions: 2788 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 2564 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 2609 length of database: 68,354,980 effective HSP length: 89 effective length of database: 51,913,565 effective search space used: 1713147645 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)