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Planaria EST Database

Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= DrC_00023
         (665 letters)

Database: Non-redundant SwissProt sequences 
           184,735 sequences; 68,354,980 total letters



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

sp|P23785|GRN_RAT  Granulins precursor [Contains: Acrogranin...   116   6e-26
sp|P28797|GRN_CAVPO  Granulins precursor (Proepithelin) (PEP...   115   1e-25
sp|P28798|GRN_MOUSE  Granulins precursor (Acrogranin) (Proep...   114   3e-25
sp|P28799|GRN_HUMAN  Granulins precursor (Proepithelin) (PEP...   113   5e-25
sp|P80059|PMD1_LOCMI  Pars intercerebralis major peptide D1 ...    64   5e-10
sp|P80930|ENA1_HORSE  Antimicrobial peptide eNAP-1                 59   9e-09
sp|P81013|GRN1_CYPCA  Granulin-1                                   55   1e-07
sp|P81015|GRN3_CYPCA  Granulin-3                                   54   4e-07
sp|P81014|GRN2_CYPCA  Granulin-2                                   50   5e-06
sp|P25777|ORYB_ORYSA  Oryzain beta chain precursor                 44   5e-04

>sp|P23785|GRN_RAT Granulins precursor [Contains: Acrogranin; Granulin-1 (Granulin G);
           Granulin-2 (Granulin F); Granulin-3 (Granulin B)
           (Epithelin-2); Granulin-4 (Granulin A) (Epithelin-1);
           Granulin-5 (Granulin C); Granulin-6 (Granulin D);
           Granulin-7 (Granulin E)]
          Length = 588

 Score =  116 bits (290), Expect = 6e-26
 Identities = 55/151 (36%), Positives = 73/151 (48%), Gaps = 2/151 (1%)
 Frame = +1

Query: 91  ICQNGKALCGDQKTCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNE 270
           +C + K  C D  TCC   +G + CC   NA+CC D LHCCP+ T CDL+  +CI +   
Sbjct: 205 VCPDAKTQCPDDSTCCELPTGKYGCCPMPNAICCSDHLHCCPQDTVCDLIQSKCISK--- 261

Query: 271 PIEWPVVETIDSAKIETPKYTVERSTLREFMIKIGDKNNCPDGGQCAGLQTCCLMYTGHY 450
                  +       + P Y V         +K   + +CPDG       TCC + TG +
Sbjct: 262 -------DYTTDLMTKLPGYPVNE-------VKCDLEVSCPDG------YTCCRLNTGAW 301

Query: 451 GCCPFSLGVCCPDLRTCCAPGYHC--VTGGC 537
           GCCPF+  VCC D   CC  G+ C   TG C
Sbjct: 302 GCCPFTKAVCCEDHIHCCPAGFQCHTETGTC 332

 Score = 96.7 bits (239), Expect = 5e-20
 Identities = 48/143 (33%), Positives = 63/143 (44%)
 Frame = +1

Query: 94  CQNGKALCGDQKTCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEP 273
           C   +  C D  TCC    G   CC    A CC D++HCCP G +CDLV+ RCI  +   
Sbjct: 125 CPGSQFECPDSATCCIMIDGSWGCCPMPQASCCEDRVHCCPHGASCDLVHTRCISPTG-- 182

Query: 274 IEWPVVETIDSAKIETPKYTVERSTLREFMIKIGDKNNCPDGGQCAGLQTCCLMYTGHYG 453
              P+++       + P     R+     ++    K  CPD        TCC + TG YG
Sbjct: 183 -THPLLK-------KFPAQRTNRAVASFSVVCPDAKTQCPDD------STCCELPTGKYG 228

Query: 454 CCPFSLGVCCPDLRTCCAPGYHC 522
           CCP    +CC D   CC     C
Sbjct: 229 CCPMPNAICCSDHLHCCPQDTVC 251

 Score = 95.9 bits (237), Expect = 8e-20
 Identities = 50/140 (35%), Positives = 64/140 (45%)
 Frame = +1

Query: 115 CGDQKTCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVE 294
           C   +TCC S  G   CCQ  +AVCC D+ HCCP G TC++  + C              
Sbjct: 447 CPVGQTCCPSLKGSWACCQLPHAVCCEDRQHCCPAGYTCNVKARTC-------------- 492

Query: 295 TIDSAKIETPKYTVERSTLREFMIKIGDKNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLG 474
                  E    +V+ S    F  K+G+   C  G  C   Q+CC    G + CCP+  G
Sbjct: 493 -------EKDAGSVQPSMDLTFGSKVGNV-ECGAGHFCHDNQSCCKDSQGGWACCPYVKG 544

Query: 475 VCCPDLRTCCAPGYHCVTGG 534
           VCC D R CC  G+HC   G
Sbjct: 545 VCCRDGRHCCPIGFHCSAKG 564

 Score = 90.9 bits (224), Expect = 3e-18
 Identities = 43/140 (30%), Positives = 64/140 (45%)
 Frame = +1

Query: 115 CGDQKTCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVE 294
           C D  TCC   +G   CC ++ AVCC D +HCCP G  C      C       ++ P ++
Sbjct: 287 CPDGYTCCRLNTGAWGCCPFTKAVCCEDHIHCCPAGFQCHTETGTC---ELGVLQVPWMK 343

Query: 295 TIDSAKIETPKYTVERSTLREFMIKIGDKNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLG 474
            + +A +  P   + ++ +            C D   C    TCC + +G +GCCP    
Sbjct: 344 KV-TASLSLPDPQILKNDVP-----------CDDFSSCPSNNTCCRLSSGDWGCCPMPEA 391

Query: 475 VCCPDLRTCCAPGYHCVTGG 534
           VCC D + CC  G+ C+  G
Sbjct: 392 VCCLDHQHCCPQGFKCMDEG 411

 Score = 78.6 bits (192), Expect = 1e-14
 Identities = 44/136 (32%), Positives = 54/136 (39%)
 Frame = +1

Query: 115 CGDQKTCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVE 294
           C    TCC   SG   CC    AVCC D  HCCP+G  C              ++    +
Sbjct: 369 CPSNNTCCRLSSGDWGCCPMPEAVCCLDHQHCCPQGFKC--------------MDEGYCQ 414

Query: 295 TIDSAKIETPKYTVERSTLREFMIKIGDKNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLG 474
             D       K  V ++TL    ++ GD   C     C   QTCC    G + CC     
Sbjct: 415 KGDRMVAGLEKMPVRQTTL----LQHGDIG-CDQHTSCPVGQTCCPSLKGSWACCQLPHA 469

Query: 475 VCCPDLRTCCAPGYHC 522
           VCC D + CC  GY C
Sbjct: 470 VCCEDRQHCCPAGYTC 485

 Score = 76.6 bits (187), Expect = 5e-14
 Identities = 41/136 (30%), Positives = 51/136 (37%)
 Frame = +1

Query: 115 CGDQKTCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVE 294
           C D  +C  + SG   CC +S  V C D  HCCP G  C    K C   S+  +      
Sbjct: 67  CPDGYSCLLTVSGTSSCCPFSEGVSCDDGQHCCPRGFHCSADGKSCSQISDSLL------ 120

Query: 295 TIDSAKIETPKYTVERSTLREFMIKIGDKNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLG 474
                 ++ P                G +  CPD        TCC+M  G +GCCP    
Sbjct: 121 ----GAVQCP----------------GSQFECPDSA------TCCIMIDGSWGCCPMPQA 154

Query: 475 VCCPDLRTCCAPGYHC 522
            CC D   CC  G  C
Sbjct: 155 SCCEDRVHCCPHGASC 170

 Score = 60.1 bits (144), Expect = 5e-09
 Identities = 25/86 (29%), Positives = 37/86 (43%), Gaps = 9/86 (10%)
 Frame = +1

Query: 31  CNILQHVIAKTPGLLKENLNICQNGKA---------LCGDQKTCCASKSGGHQCCQYSNA 183
           CN+      K  G ++ ++++    K           C D ++CC    GG  CC Y   
Sbjct: 485 CNVKARTCEKDAGSVQPSMDLTFGSKVGNVECGAGHFCHDNQSCCKDSQGGWACCPYVKG 544

Query: 184 VCCGDQLHCCPEGTTCDLVNKRCIHQ 261
           VCC D  HCCP G  C     +C+ +
Sbjct: 545 VCCRDGRHCCPIGFHCSAKGTKCLRK 570

 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 22/52 (42%), Positives = 29/52 (55%)
 Frame = +1

Query: 379 KNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHCVTGG 534
           +++CPDG       +C L  +G   CCPFS GV C D + CC  G+HC   G
Sbjct: 64  RDHCPDG------YSCLLTVSGTSSCCPFSEGVSCDDGQHCCPRGFHCSADG 109

>sp|P28797|GRN_CAVPO Granulins precursor (Proepithelin) (PEPI) [Contains: Acrogranin;
           Granulin-1; Granulin-2; Granulin-3; Granulin-4;
           Granulin-5; Granulin-6; Granulin-7]
          Length = 591

 Score =  115 bits (287), Expect = 1e-25
 Identities = 57/159 (35%), Positives = 79/159 (49%), Gaps = 3/159 (1%)
 Frame = +1

Query: 61  TPGLLKENLN---ICQNGKALCGDQKTCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTC 231
           +PGLL   L    IC + ++ C D  TCC   SG + CC   NA+CC D LHCCP+ T C
Sbjct: 194 SPGLLPAALPTSVICPDSRSQCPDDTTCCLLASGEYGCCPMPNAICCSDHLHCCPQDTVC 253

Query: 232 DLVNKRCIHQSNEPIEWPVVETIDSAKIETPKYTVERSTLREFMIKIGDKNNCPDGGQCA 411
           DL   RC+ Q+             +   + P +TV       + ++   + +CP+G    
Sbjct: 254 DLRQSRCLSQNK----------AKTLLTKLPSWTV-------WDVECDQEVSCPEG---- 292

Query: 412 GLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHCVT 528
             QTCC + +G +GCCPF   VCC D   CC   + C T
Sbjct: 293 --QTCCRLQSGKWGCCPFPKAVCCEDHVHCCPERFRCHT 329

 Score =  103 bits (256), Expect = 5e-22
 Identities = 54/154 (35%), Positives = 72/154 (46%)
 Frame = +1

Query: 73  LKENLNICQNGKALCGDQKTCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRC 252
           L +  ++  +  A C  ++TCC    GG  CCQ  +AVCC D  HCCP G TC++  + C
Sbjct: 433 LSQTTDVGCDQHASCPVRQTCCPKLGGGWACCQLPHAVCCEDGQHCCPAGYTCNVKARSC 492

Query: 253 IHQSNEPIEWPVVETIDSAKIETPKYTVERSTLREFMIKIGDKNNCPDGGQCAGLQTCCL 432
                        +  D A +  P      ST     +  GD++ C D       QTCC 
Sbjct: 493 ------------EKAADGAHLAAP--LAVGSTGGVMDVACGDRHFCHDE------QTCCR 532

Query: 433 MYTGHYGCCPFSLGVCCPDLRTCCAPGYHCVTGG 534
              G + CCPF  GVCC D R CC  G+HC + G
Sbjct: 533 DSRGGWACCPFHQGVCCKDQRHCCPAGFHCESQG 566

 Score = 99.0 bits (245), Expect = 1e-20
 Identities = 53/149 (35%), Positives = 70/149 (46%), Gaps = 6/149 (4%)
 Frame = +1

Query: 94  CQNGKALCGDQKTCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQ-SNE 270
           C  G+  C D  TCC    G   CC    A CC D++HCCP G +CDLV+ RC+    + 
Sbjct: 112 CPGGEFECPDSSTCCHMLDGSWGCCPMPQASCCEDRVHCCPHGASCDLVHIRCVTALGSH 171

Query: 271 PI--EWPVVETIDSAKIETPKYT--VERSTLREFMIKIGDKNNCPDG-GQCAGLQTCCLM 435
           P+  + P   T  +    TP  +  +  + L   +I       CPD   QC    TCCL+
Sbjct: 172 PLTTKLPAQRTNYTGAEGTPVVSPGLLPAALPTSVI-------CPDSRSQCPDDTTCCLL 224

Query: 436 YTGHYGCCPFSLGVCCPDLRTCCAPGYHC 522
            +G YGCCP    +CC D   CC     C
Sbjct: 225 ASGEYGCCPMPNAICCSDHLHCCPQDTVC 253

 Score = 67.4 bits (163), Expect = 3e-11
 Identities = 23/61 (37%), Positives = 34/61 (55%)
 Frame = +1

Query: 85  LNICQNGKALCGDQKTCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQS 264
           +++    +  C D++TCC    GG  CC +   VCC DQ HCCP G  C+    RC+H+ 
Sbjct: 514 MDVACGDRHFCHDEQTCCRDSRGGWACCPFHQGVCCKDQRHCCPAGFHCESQGTRCVHKK 573

Query: 265 N 267
           +
Sbjct: 574 S 574

 Score = 66.6 bits (161), Expect = 5e-11
 Identities = 35/123 (28%), Positives = 50/123 (40%)
 Frame = +1

Query: 115 CGDQKTCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVE 294
           C + +TCC  +SG   CC +  AVCC D +HCCPE   C      C  Q    + W    
Sbjct: 289 CPEGQTCCRLQSGKWGCCPFPKAVCCEDHVHCCPERFRCHTEKDTC-EQGLLQVPWAQKT 347

Query: 295 TIDSAKIETPKYTVERSTLREFMIKIGDKNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLG 474
               ++   P               +  + +C +   C     CC + +G +GCCP S G
Sbjct: 348 PAQPSRPSQPSPPGPPGPPSP-PGPLRSEISCDEVVSCRPGNICCRLASGEWGCCPSSEG 406

Query: 475 VCC 483
             C
Sbjct: 407 YLC 409

 Score = 64.3 bits (155), Expect = 3e-10
 Identities = 41/150 (27%), Positives = 55/150 (36%), Gaps = 1/150 (0%)
 Frame = +1

Query: 94  CQNGKALCGDQKTCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEP 273
           CQ+  A C    +C  + +G   CC +S A+ CGD  HCCP G  C      CI +    
Sbjct: 47  CQS-PANCPIGHSCVLTAAGTAACCPFSQAMACGDGHHCCPYGFHCSTDGGTCIQR---- 101

Query: 274 IEWPVVETIDSAKIETPKYTVERSTLREFMIKIGDKNNCPDGG-QCAGLQTCCLMYTGHY 450
              P +  + + +                         CP G  +C    TCC M  G +
Sbjct: 102 ---PDIHLLGAVQ-------------------------CPGGEFECPDSSTCCHMLDGSW 133

Query: 451 GCCPFSLGVCCPDLRTCCAPGYHCVTGGCA 540
           GCCP     CC D         HC   G +
Sbjct: 134 GCCPMPQASCCED-------RVHCCPHGAS 156

>sp|P28798|GRN_MOUSE Granulins precursor (Acrogranin) (Proepithelin) (PEPI) (PC
           cell-derived growth factor) (PCDGF) [Contains: Granulin
           1; Granulin 2; Granulin 3; Granulin 4; Granulin 5;
           Granulin 6; Granulin 7]
          Length = 589

 Score =  114 bits (284), Expect = 3e-25
 Identities = 53/146 (36%), Positives = 74/146 (50%)
 Frame = +1

Query: 91  ICQNGKALCGDQKTCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNE 270
           +C + K  C D  TCC   +G + CC   NA+CC D LHCCP+ T CDL+  +C+ ++  
Sbjct: 206 VCPDAKTQCPDDSTCCELPTGKYGCCPMPNAICCSDHLHCCPQDTVCDLIQSKCLSKN-- 263

Query: 271 PIEWPVVETIDSAKIETPKYTVERSTLREFMIKIGDKNNCPDGGQCAGLQTCCLMYTGHY 450
                   T D    + P Y V+        +K   + +CP+G       TCC + TG +
Sbjct: 264 -------YTTD-LLTKLPGYPVKE-------VKCDMEVSCPEG------YTCCRLNTGAW 302

Query: 451 GCCPFSLGVCCPDLRTCCAPGYHCVT 528
           GCCPF+  VCC D   CC  G+ C T
Sbjct: 303 GCCPFAKAVCCEDHIHCCPAGFQCHT 328

 Score = 99.4 bits (246), Expect = 8e-21
 Identities = 51/140 (36%), Positives = 68/140 (48%)
 Frame = +1

Query: 115 CGDQKTCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVE 294
           C   +TCC S  G   CCQ  +AVCC D+ HCCP G TC++  + C  +  + I+ PV+ 
Sbjct: 448 CPVGQTCCPSLKGSWACCQLPHAVCCEDRQHCCPAGYTCNVKARTC-EKDVDFIQPPVLL 506

Query: 295 TIDSAKIETPKYTVERSTLREFMIKIGDKNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLG 474
           T+                      K+G+   C +G  C   QTCC    G + CCP+  G
Sbjct: 507 TLGP--------------------KVGNV-ECGEGHFCHDNQTCCKDSAGVWACCPYLKG 545

Query: 475 VCCPDLRTCCAPGYHCVTGG 534
           VCC D R CC  G+HC   G
Sbjct: 546 VCCRDGRHCCPGGFHCSARG 565

 Score = 97.1 bits (240), Expect = 4e-20
 Identities = 48/144 (33%), Positives = 61/144 (42%), Gaps = 1/144 (0%)
 Frame = +1

Query: 94  CQNGKALCGDQKTCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEP 273
           C   +  C D  TCC    G   CC    A CC D++HCCP G +CDLV+ RC+  +   
Sbjct: 125 CPGSQFECPDSATCCIMVDGSWGCCPMPQASCCEDRVHCCPHGASCDLVHTRCVSPTG-- 182

Query: 274 IEWPVVETIDSAKIETPKYTVERSTLREFMIKIGD-KNNCPDGGQCAGLQTCCLMYTGHY 450
                     +   + P     R+    F +   D K  CPD        TCC + TG Y
Sbjct: 183 --------THTLLKKFPAQKTNRAVSLPFSVVCPDAKTQCPDD------STCCELPTGKY 228

Query: 451 GCCPFSLGVCCPDLRTCCAPGYHC 522
           GCCP    +CC D   CC     C
Sbjct: 229 GCCPMPNAICCSDHLHCCPQDTVC 252

 Score = 92.0 bits (227), Expect = 1e-18
 Identities = 47/167 (28%), Positives = 71/167 (42%)
 Frame = +1

Query: 34  NILQHVIAKTPGLLKENLNICQNGKALCGDQKTCCASKSGGHQCCQYSNAVCCGDQLHCC 213
           N    ++ K PG   + +    + +  C +  TCC   +G   CC ++ AVCC D +HCC
Sbjct: 263 NYTTDLLTKLPGYPVKEVKC--DMEVSCPEGYTCCRLNTGAWGCCPFAKAVCCEDHIHCC 320

Query: 214 PEGTTCDLVNKRCIHQSNEPIEWPVVETIDSAKIETPKYTVERSTLREFMIKIGDKNNCP 393
           P G  C        H      E  +++     K+  P    +   L+           C 
Sbjct: 321 PAGFQC--------HTEKGTCEMGILQVPWMKKVIAPLRLPDPQILKS-------DTPCD 365

Query: 394 DGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHCVTGG 534
           D  +C    TCC + +G +GCCP    VCC D + CC  G+ C+  G
Sbjct: 366 DFTRCPTNNTCCKLNSGDWGCCPIPEAVCCSDNQHCCPQGFTCLAQG 412

 Score = 83.2 bits (204), Expect = 6e-16
 Identities = 42/136 (30%), Positives = 53/136 (38%)
 Frame = +1

Query: 115 CGDQKTCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVE 294
           C    +C  + SG   CC +S  V CGD  HCCP+G  C    K C   S+ P+      
Sbjct: 67  CPAGYSCLLTVSGTSSCCPFSKGVSCGDGYHCCPQGFHCSADGKSCFQMSDNPL------ 120

Query: 295 TIDSAKIETPKYTVERSTLREFMIKIGDKNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLG 474
                 ++ P                G +  CPD        TCC+M  G +GCCP    
Sbjct: 121 ----GAVQCP----------------GSQFECPDSA------TCCIMVDGSWGCCPMPQA 154

Query: 475 VCCPDLRTCCAPGYHC 522
            CC D   CC  G  C
Sbjct: 155 SCCEDRVHCCPHGASC 170

 Score = 82.8 bits (203), Expect = 7e-16
 Identities = 47/137 (34%), Positives = 56/137 (40%), Gaps = 1/137 (0%)
 Frame = +1

Query: 115 CGDQKTCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVE 294
           C    TCC   SG   CC    AVCC D  HCCP+G TC L    C              
Sbjct: 370 CPTNNTCCKLNSGDWGCCPIPEAVCCSDNQHCCPQGFTC-LAQGYC-------------- 414

Query: 295 TIDSAKIETPKYTVERSTLREFM-IKIGDKNNCPDGGQCAGLQTCCLMYTGHYGCCPFSL 471
                K +T    +E+   R+   ++IGD   C     C   QTCC    G + CC    
Sbjct: 415 ----QKGDTMVAGLEKIPARQTTPLQIGDIG-CDQHTSCPVGQTCCPSLKGSWACCQLPH 469

Query: 472 GVCCPDLRTCCAPGYHC 522
            VCC D + CC  GY C
Sbjct: 470 AVCCEDRQHCCPAGYTC 486

 Score = 55.5 bits (132), Expect = 1e-07
 Identities = 20/49 (40%), Positives = 25/49 (51%)
 Frame = +1

Query: 115 CGDQKTCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQ 261
           C D +TCC   +G   CC Y   VCC D  HCCP G  C     +C+ +
Sbjct: 523 CHDNQTCCKDSAGVWACCPYLKGVCCRDGRHCCPGGFHCSARGTKCLRK 571

 Score = 51.2 bits (121), Expect = 2e-06
 Identities = 21/50 (42%), Positives = 25/50 (50%)
 Frame = +1

Query: 385 NCPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHCVTGG 534
           +C   G C    +C L  +G   CCPFS GV C D   CC  G+HC   G
Sbjct: 60  SCQTHGHCPAGYSCLLTVSGTSSCCPFSKGVSCGDGYHCCPQGFHCSADG 109

>sp|P28799|GRN_HUMAN Granulins precursor (Proepithelin) (PEPI) [Contains: Acrogranin;
           Paragranulin; Granulin-1 (Granulin G); Granulin-2
           (Granulin F); Granulin-3 (Granulin B); Granulin-4
           (Granulin A); Granulin-5 (Granulin C); Granulin-6
           (Granulin D); Granulin-7 (Granulin E)]
          Length = 593

 Score =  113 bits (282), Expect = 5e-25
 Identities = 52/146 (35%), Positives = 73/146 (50%)
 Frame = +1

Query: 91  ICQNGKALCGDQKTCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNE 270
           +C + ++ C D  TCC   SG + CC   NA CC D LHCCP+ T CDL+  +C+ + N 
Sbjct: 207 MCPDARSRCPDGSTCCELPSGKYGCCPMPNATCCSDHLHCCPQDTVCDLIQSKCLSKENA 266

Query: 271 PIEWPVVETIDSAKIETPKYTVERSTLREFMIKIGDKNNCPDGGQCAGLQTCCLMYTGHY 450
             +            + P +TV         +K   + +CPDG       TCC + +G +
Sbjct: 267 TTD---------LLTKLPAHTVGD-------VKCDMEVSCPDG------YTCCRLQSGAW 304

Query: 451 GCCPFSLGVCCPDLRTCCAPGYHCVT 528
           GCCPF+  VCC D   CC  G+ C T
Sbjct: 305 GCCPFTQAVCCEDHIHCCPAGFTCDT 330

 Score =  101 bits (252), Expect = 2e-21
 Identities = 56/176 (31%), Positives = 77/176 (43%)
 Frame = +1

Query: 25  ALCNILQHVIAKTPGLLKENLNICQNGKALCGDQKTCCASKSGGHQCCQYSNAVCCGDQL 204
           A  ++L  + A T G +K ++ +       C D  TCC  +SG   CC ++ AVCC D +
Sbjct: 266 ATTDLLTKLPAHTVGDVKCDMEVS------CPDGYTCCRLQSGAWGCCPFTQAVCCEDHI 319

Query: 205 HCCPEGTTCDLVNKRCIHQSNEPIEWPVVETIDSAKIETPKYTVERSTLREFMIKIGDKN 384
           HCCP G TCD     C      P + P +E   +         ++R              
Sbjct: 320 HCCPAGFTCDTQKGTC---EQGPHQVPWMEKAPAHLSLPDPQALKRDV------------ 364

Query: 385 NCPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHCVTGGCA*LGS 552
            C +   C    TCC + +G +GCCP    VCC D + CC  GY CV  G    GS
Sbjct: 365 PCDNVSSCPSSDTCCQLTSGEWGCCPIPEAVCCSDHQHCCPQGYTCVAEGQCQRGS 420

 Score = 95.1 bits (235), Expect = 1e-19
 Identities = 50/144 (34%), Positives = 63/144 (43%), Gaps = 1/144 (0%)
 Frame = +1

Query: 94  CQNGKALCGDQKTCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEP 273
           C + +  C D  TCC    G   CC    A CC D++HCCP G  CDLV+ RCI  +   
Sbjct: 126 CPDSQFECPDFSTCCVMVDGSWGCCPMPQASCCEDRVHCCPHGAFCDLVHTRCITPTG-- 183

Query: 274 IEWPVVETIDSAKIETPKYTVERSTLREFMIKIGD-KNNCPDGGQCAGLQTCCLMYTGHY 450
                  T   AK + P     R+      +   D ++ CPDG       TCC + +G Y
Sbjct: 184 -------THPLAK-KLPAQRTNRAVALSSSVMCPDARSRCPDG------STCCELPSGKY 229

Query: 451 GCCPFSLGVCCPDLRTCCAPGYHC 522
           GCCP     CC D   CC     C
Sbjct: 230 GCCPMPNATCCSDHLHCCPQDTVC 253

 Score = 93.6 bits (231), Expect = 4e-19
 Identities = 47/141 (33%), Positives = 62/141 (43%), Gaps = 1/141 (0%)
 Frame = +1

Query: 115 CGDQKTCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVE 294
           C   +TCC S  G   CCQ  +AVCC D+ HCCP G TC++  + C              
Sbjct: 450 CPVGQTCCPSLGGSWACCQLPHAVCCEDRQHCCPAGYTCNVKARSC-------------- 495

Query: 295 TIDSAKIETPKYTVERSTLREFMIKIGDKN-NCPDGGQCAGLQTCCLMYTGHYGCCPFSL 471
                  E    + + +T       +G K+  C +G  C   QTCC      + CCP+  
Sbjct: 496 -------EKEVVSAQPATFLARSPHVGVKDVECGEGHFCHDNQTCCRDNRQGWACCPYRQ 548

Query: 472 GVCCPDLRTCCAPGYHCVTGG 534
           GVCC D R CC  G+ C   G
Sbjct: 549 GVCCADRRHCCPAGFRCAARG 569

 Score = 82.4 bits (202), Expect = 1e-15
 Identities = 52/159 (32%), Positives = 65/159 (40%)
 Frame = +1

Query: 46  HVIAKTPGLLKENLNICQNGKALCGDQKTCCASKSGGHQCCQYSNAVCCGDQLHCCPEGT 225
           H+    P  LK ++  C N  + C    TCC   SG   CC    AVCC D  HCCP+G 
Sbjct: 351 HLSLPDPQALKRDVP-CDNVSS-CPSSDTCCQLTSGEWGCCPIPEAVCCSDHQHCCPQGY 408

Query: 226 TCDLVNKRCIHQSNEPIEWPVVETIDSAKIETPKYTVERSTLREFMIKIGDKNNCPDGGQ 405
           TC +   +C   S           I +   + P      S  R+  I      +CP G  
Sbjct: 409 TC-VAEGQCQRGSE----------IVAGLEKMPARRASLSHPRD--IGCDQHTSCPVG-- 453

Query: 406 CAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHC 522
               QTCC    G + CC     VCC D + CC  GY C
Sbjct: 454 ----QTCCPSLGGSWACCQLPHAVCCEDRQHCCPAGYTC 488

 Score = 77.8 bits (190), Expect = 2e-14
 Identities = 44/159 (27%), Positives = 56/159 (35%), Gaps = 1/159 (0%)
 Frame = +1

Query: 49  VIAKTPGLLKENLNICQNGKALCGDQKTCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTT 228
           ++ K P  L  +L       A C    +C  + SG   CC +  AV CGD  HCCP G  
Sbjct: 45  LLDKWPTTLSRHLGGPCQVDAHCSAGHSCIFTVSGTSSCCPFPEAVACGDGHHCCPRGFH 104

Query: 229 CDLVNKRCIHQSNEPIEWPVVETIDSAKIETPKYTVERSTLREFMIKIGDKNNCPDGG-Q 405
           C    + C  +S       +                                 CPD   +
Sbjct: 105 CSADGRSCFQRSGNNSVGAI--------------------------------QCPDSQFE 132

Query: 406 CAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHC 522
           C    TCC+M  G +GCCP     CC D   CC  G  C
Sbjct: 133 CPDFSTCCVMVDGSWGCCPMPQASCCEDRVHCCPHGAFC 171

 Score = 57.4 bits (137), Expect = 3e-08
 Identities = 20/49 (40%), Positives = 25/49 (51%)
 Frame = +1

Query: 115 CGDQKTCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQ 261
           C D +TCC     G  CC Y   VCC D+ HCCP G  C     +C+ +
Sbjct: 527 CHDNQTCCRDNRQGWACCPYRQGVCCADRRHCCPAGFRCAARGTKCLRR 575

 Score = 43.9 bits (102), Expect = 4e-04
 Identities = 17/49 (34%), Positives = 21/49 (42%)
 Frame = +1

Query: 388 CPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHCVTGG 534
           C     C+   +C    +G   CCPF   V C D   CC  G+HC   G
Sbjct: 61  CQVDAHCSAGHSCIFTVSGTSSCCPFPEAVACGDGHHCCPRGFHCSADG 109

>sp|P80059|PMD1_LOCMI Pars intercerebralis major peptide D1 (PMP-D1)
          Length = 54

 Score = 63.5 bits (153), Expect = 5e-10
 Identities = 23/47 (48%), Positives = 28/47 (59%)
 Frame = +1

Query: 115 CGDQKTCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCI 255
           C   +TCC +  G   CC Y   VCC D +HCCP GT CD  ++RCI
Sbjct: 7   CPGTETCCTTPQGEEGCCPYKEGVCCLDGIHCCPSGTVCDEDHRRCI 53

 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 19/39 (48%), Positives = 21/39 (53%)
 Frame = +1

Query: 406 CAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHC 522
           C G +TCC    G  GCCP+  GVCC D   CC  G  C
Sbjct: 7   CPGTETCCTTPQGEEGCCPYKEGVCCLDGIHCCPSGTVC 45

>sp|P80930|ENA1_HORSE Antimicrobial peptide eNAP-1
          Length = 46

 Score = 59.3 bits (142), Expect = 9e-09
 Identities = 21/36 (58%), Positives = 23/36 (63%)
 Frame = +1

Query: 115 CGDQKTCCASKSGGHQCCQYSNAVCCGDQLHCCPEG 222
           C D +TCC +  GG  CC YS  VCC DQ HCCP G
Sbjct: 10  CHDXQTCCRASQGGXACCPYSQGVCCADQRHCCPVG 45

 Score = 53.9 bits (128), Expect = 4e-07
 Identities = 21/43 (48%), Positives = 24/43 (55%)
 Frame = +1

Query: 388 CPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGY 516
           C +G  C   QTCC    G   CCP+S GVCC D R CC  G+
Sbjct: 4   CGEGHFCHDXQTCCRASQGGXACCPYSQGVCCADQRHCCPVGF 46

>sp|P81013|GRN1_CYPCA Granulin-1
          Length = 57

 Score = 55.5 bits (132), Expect = 1e-07
 Identities = 24/45 (53%), Positives = 26/45 (57%)
 Frame = +1

Query: 388 CPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHC 522
           CPDG       TCCL   G + CCPFS+G CC D   CC  GYHC
Sbjct: 10  CPDG------TTCCLSPYGVWYCCPFSMGQCCRDGIHCCRHGYHC 48

 Score = 53.5 bits (127), Expect = 5e-07
 Identities = 20/48 (41%), Positives = 25/48 (52%)
 Frame = +1

Query: 112 LCGDQKTCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCI 255
           +C D  TCC S  G   CC +S   CC D +HCC  G  CD  +  C+
Sbjct: 9   ICPDGTTCCLSPYGVWYCCPFSMGQCCRDGIHCCRHGYHCDSTSTHCL 56

>sp|P81015|GRN3_CYPCA Granulin-3
          Length = 57

 Score = 53.9 bits (128), Expect = 4e-07
 Identities = 22/45 (48%), Positives = 24/45 (53%)
 Frame = +1

Query: 388 CPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHC 522
           C  G  C    TCC    G + CCPF +G CC D R CC  GYHC
Sbjct: 4   CDAGITCPSGTTCCRSPFGVWYCCPFLMGQCCRDGRHCCRHGYHC 48

 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 18/47 (38%), Positives = 21/47 (44%)
 Frame = +1

Query: 115 CGDQKTCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCI 255
           C    TCC S  G   CC +    CC D  HCC  G  CD  +  C+
Sbjct: 10  CPSGTTCCRSPFGVWYCCPFLMGQCCRDGRHCCRHGYHCDSTSTLCL 56

>sp|P81014|GRN2_CYPCA Granulin-2
          Length = 57

 Score = 50.1 bits (118), Expect = 5e-06
 Identities = 19/52 (36%), Positives = 24/52 (46%)
 Frame = +1

Query: 100 NGKALCGDQKTCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCI 255
           N +  C  + TCC S  G   CC +    CC D  HCC  G  CD  +  C+
Sbjct: 5   NARTTCPSRTTCCRSPFGVWYCCPFLMGQCCRDGRHCCRHGYRCDSTSTLCL 56

 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 19/39 (48%), Positives = 21/39 (53%)
 Frame = +1

Query: 406 CAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHC 522
           C    TCC    G + CCPF +G CC D R CC  GY C
Sbjct: 10  CPSRTTCCRSPFGVWYCCPFLMGQCCRDGRHCCRHGYRC 48

>sp|P25777|ORYB_ORYSA Oryzain beta chain precursor
          Length = 471

 Score = 43.5 bits (101), Expect = 5e-04
 Identities = 19/50 (38%), Positives = 24/50 (48%), Gaps = 3/50 (6%)
 Frame = +1

Query: 376 DKNNCPDGGQCA---GLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGY 516
           D  +CP G  C    G +  CL++    GCCP     CC D  +CC P Y
Sbjct: 387 DNFSCPAGSTCCCAFGFRNLCLVW----GCCPVEGATCCKDHASCCPPDY 432

 Score = 33.1 bits (74), Expect = 0.67
 Identities = 17/60 (28%), Positives = 22/60 (36%), Gaps = 6/60 (10%)
 Frame = +1

Query: 115 CGDQKTCCASKSGGHQC-----CQYSNAVCCGDQLHCC-PEGTTCDLVNKRCIHQSNEPI 276
           C    TCC +    + C     C    A CC D   CC P+   C+     C    N P+
Sbjct: 391 CPAGSTCCCAFGFRNLCLVWGCCPVEGATCCKDHASCCPPDYPVCNTRAGTCSASKNSPL 450

  Database: Non-redundant SwissProt sequences
    Posted date:  Dec 6, 2005  7:40 AM
  Number of letters in database: 68,354,980
  Number of sequences in database:  184,735
  
  Database: swissprot.01
    Posted date:  Dec 6, 2005  8:18 AM
  Number of letters in database: 66,202,850
  Number of sequences in database:  184,431
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 77,387,228
Number of Sequences: 369166
Number of extensions: 1734956
Number of successful extensions: 6026
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 5163
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5877
length of database: 68,354,980
effective HSP length: 106
effective length of database: 48,773,070
effective search space used: 5608903050
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)

Cluster detail

1. Dr_sW_014_N17
2. Dr_sW_023_F22
3. Dr_sW_028_A15
4. Dr_sW_022_C07
5. Dr_sW_022_C09
6. Dr_sW_014_E22
7. Dr_sW_028_B05
8. Dr_sW_014_B11
9. Dr_sW_024_I03
10. Dr_sW_001_I17
11. Dr_sW_014_E23
12. Dr_sW_004_G05
13. Dr_sW_006_F19
14. Dr_sW_008_M13
15. Dr_sW_020_P16
16. Dr_sW_018_I18
17. Dr_sW_017_P13
18. Dr_sW_011_C01
19. Dr_sW_007_A21
20. Dr_sW_017_D18
21. Dr_sW_003_N19
22. Dr_sW_008_G23
23. Dr_sW_018_J11
24. Dr_sW_019_K16
25. Dr_sW_001_M10
26. Dr_sW_026_E02
27. Dr_sW_025_B06
28. Dr_sW_015_A10
29. Dr_sW_013_F18
30. Dr_sW_007_F23
31. Dr_sW_020_L02
32. Dr_sW_018_A05
33. Dr_sW_006_B12
34. Dr_sW_003_F13
35. Dr_sW_011_L02
36. Dr_sW_027_N23
37. Dr_sW_028_A14
38. Dr_sW_020_B22
39. Dr_sW_026_A11
40. Dr_sW_006_H20
41. Dr_sW_010_F07
42. Dr_sW_009_L07
43. Dr_sW_023_K07
44. Dr_sW_008_C04
45. Dr_sW_013_E11
46. Dr_sW_007_E03
47. Dr_sW_003_M08
48. Dr_sW_011_I17
49. Dr_sW_028_I19
50. Dr_sW_006_H13
51. Dr_sW_028_F21
52. Dr_sW_001_C22
53. Dr_sW_025_A16
54. Dr_sW_012_C20
55. Dr_sW_023_D05
56. Dr_sW_021_E14
57. Dr_sW_003_L15
58. Dr_sW_020_B20
59. Dr_sW_017_E09
60. Dr_sW_008_B19
61. Dr_sW_011_K07
62. Dr_sW_005_C03
63. Dr_sW_019_F17
64. Dr_sW_001_P21
65. Dr_sW_025_F06
66. Dr_sW_012_A13
67. Dr_sW_018_D07
68. Dr_sW_021_N03
69. Dr_sW_003_K02
70. Dr_sW_025_H01
71. Dr_sW_026_D23
72. Dr_sW_013_I12
73. Dr_sW_024_E12
74. Dr_sW_010_B11
75. Dr_sW_012_G17
76. Dr_sW_004_A16
77. Dr_sW_016_N08
78. Dr_sW_002_G07
79. Dr_sW_024_A17
80. Dr_sW_017_A13
81. Dr_sW_027_E01
82. Dr_sW_010_E10
83. Dr_sW_003_L11
84. Dr_sW_011_J14
85. Dr_sW_019_O10
86. Dr_sW_019_L04
87. Dr_sW_013_G13
88. Dr_sW_017_C05
89. Dr_sW_020_D11
90. Dr_sW_018_P12
91. Dr_sW_014_D24
92. Dr_sW_024_I23
93. Dr_sW_010_H02
94. Dr_sW_005_M07
95. Dr_sW_006_O19
96. Dr_sW_021_C12
97. Dr_sW_001_A11
98. Dr_sW_004_N24
99. Dr_sW_012_P09
100. Dr_sW_001_N18
101. Dr_sW_021_N01
102. Dr_sW_022_I08
103. Dr_sW_005_D06
104. Dr_sW_004_P14
105. Dr_sW_026_L23
106. Dr_sW_022_A24
107. Dr_sW_015_H03
108. Dr_sW_006_H21
109. Dr_sW_026_B10
110. Dr_sW_001_G02
111. Dr_sW_005_O04
112. Dr_sW_012_H05
113. Dr_sW_024_N22
114. Dr_sW_013_K13
115. Dr_sW_026_K15
116. Dr_sW_018_A18
117. Dr_sW_012_D19
118. Dr_sW_015_L14
119. Dr_sW_012_A19
120. Dr_sW_002_G06
121. Dr_sW_024_C02
122. Dr_sW_002_J08
123. Dr_sW_008_I12
124. Dr_sW_011_L22
125. Dr_sW_020_K05
126. Dr_sW_014_M16
127. Dr_sW_013_P21
128. Dr_sW_013_C22
129. Dr_sW_012_N14
130. Dr_sW_006_J18
131. Dr_sW_028_L09
132. Dr_sW_028_M19
133. Dr_sW_008_N02
134. Dr_sW_006_H04
135. Dr_sW_004_C03
136. Dr_sW_024_N24
137. Dr_sW_014_O22
138. Dr_sW_021_L08
139. Dr_sW_019_D21
140. Dr_sW_008_N18
141. Dr_sW_011_G17
142. Dr_sW_020_M13
143. Dr_sW_020_N16
144. Dr_sW_028_O05
145. Dr_sW_008_E01
146. Dr_sW_011_K17