Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_020_K05
(497 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P23785|GRN_RAT Granulins precursor [Contains: Acrogranin... 105 6e-23
sp|P28799|GRN_HUMAN Granulins precursor (Proepithelin) (PEP... 104 1e-22
sp|P28798|GRN_MOUSE Granulins precursor (Acrogranin) (Proep... 103 3e-22
sp|P28797|GRN_CAVPO Granulins precursor (Proepithelin) (PEP... 102 4e-22
sp|P80059|PMD1_LOCMI Pars intercerebralis major peptide D1 ... 62 7e-10
sp|P81013|GRN1_CYPCA Granulin-1 55 7e-08
sp|P80930|ENA1_HORSE Antimicrobial peptide eNAP-1 54 2e-07
sp|P81015|GRN3_CYPCA Granulin-3 54 2e-07
sp|P81014|GRN2_CYPCA Granulin-2 49 7e-06
sp|P25777|ORYB_ORYSA Oryzain beta chain precursor 44 3e-04
>sp|P23785|GRN_RAT Granulins precursor [Contains: Acrogranin; Granulin-1 (Granulin G);
Granulin-2 (Granulin F); Granulin-3 (Granulin B)
(Epithelin-2); Granulin-4 (Granulin A) (Epithelin-1);
Granulin-5 (Granulin C); Granulin-6 (Granulin D);
Granulin-7 (Granulin E)]
Length = 588
Score = 105 bits (262), Expect = 6e-23
Identities = 51/138 (36%), Positives = 67/138 (48%), Gaps = 2/138 (1%)
Frame = +1
Query: 4 TCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVETIDSA 183
TCC +G + CC NA+CC D LHCCP+ T CDL+ +CI + +
Sbjct: 218 TCCELPTGKYGCCPMPNAICCSDHLHCCPQDTVCDLIQSKCISK----------DYTTDL 267
Query: 184 KIETPKYTVERSTLREFMIKIGDKNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPD 363
+ P Y V +K + +CPDG TCC + TG +GCCPF+ VCC D
Sbjct: 268 MTKLPGYPVNE-------VKCDLEVSCPDG------YTCCRLNTGAWGCCPFTKAVCCED 314
Query: 364 LRTCCAPGYHC--VTGGC 411
CC G+ C TG C
Sbjct: 315 HIHCCPAGFQCHTETGTC 332
Score = 94.7 bits (234), Expect = 1e-19
Identities = 49/135 (36%), Positives = 62/135 (45%)
Frame = +1
Query: 4 TCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVETIDSA 183
TCC S G CCQ +AVCC D+ HCCP G TC++ + C
Sbjct: 452 TCCPSLKGSWACCQLPHAVCCEDRQHCCPAGYTCNVKARTC------------------- 492
Query: 184 KIETPKYTVERSTLREFMIKIGDKNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPD 363
E +V+ S F K+G+ C G C Q+CC G + CCP+ GVCC D
Sbjct: 493 --EKDAGSVQPSMDLTFGSKVGNV-ECGAGHFCHDNQSCCKDSQGGWACCPYVKGVCCRD 549
Query: 364 LRTCCAPGYHCVTGG 408
R CC G+HC G
Sbjct: 550 GRHCCPIGFHCSAKG 564
Score = 90.5 bits (223), Expect = 2e-18
Identities = 45/131 (34%), Positives = 59/131 (45%)
Frame = +1
Query: 4 TCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVETIDSA 183
TCC G CC A CC D++HCCP G +CDLV+ RCI + P+++
Sbjct: 137 TCCIMIDGSWGCCPMPQASCCEDRVHCCPHGASCDLVHTRCISPTG---THPLLK----- 188
Query: 184 KIETPKYTVERSTLREFMIKIGDKNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPD 363
+ P R+ ++ K CPD TCC + TG YGCCP +CC D
Sbjct: 189 --KFPAQRTNRAVASFSVVCPDAKTQCPDD------STCCELPTGKYGCCPMPNAICCSD 240
Query: 364 LRTCCAPGYHC 396
CC C
Sbjct: 241 HLHCCPQDTVC 251
Score = 87.4 bits (215), Expect = 2e-17
Identities = 41/135 (30%), Positives = 62/135 (45%)
Frame = +1
Query: 4 TCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVETIDSA 183
TCC +G CC ++ AVCC D +HCCP G C C ++ P ++ + +A
Sbjct: 292 TCCRLNTGAWGCCPFTKAVCCEDHIHCCPAGFQCHTETGTC---ELGVLQVPWMKKV-TA 347
Query: 184 KIETPKYTVERSTLREFMIKIGDKNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPD 363
+ P + ++ + C D C TCC + +G +GCCP VCC D
Sbjct: 348 SLSLPDPQILKNDVP-----------CDDFSSCPSNNTCCRLSSGDWGCCPMPEAVCCLD 396
Query: 364 LRTCCAPGYHCVTGG 408
+ CC G+ C+ G
Sbjct: 397 HQHCCPQGFKCMDEG 411
Score = 76.3 bits (186), Expect = 4e-14
Identities = 43/132 (32%), Positives = 54/132 (40%)
Frame = +1
Query: 1 DTCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVETIDS 180
+TCC SG CC AVCC D HCCP+G C ++ + D
Sbjct: 373 NTCCRLSSGDWGCCPMPEAVCCLDHQHCCPQGFKC--------------MDEGYCQKGDR 418
Query: 181 AKIETPKYTVERSTLREFMIKIGDKNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCP 360
K V ++TL ++ GD C C QTCC G + CC VCC
Sbjct: 419 MVAGLEKMPVRQTTL----LQHGD-IGCDQHTSCPVGQTCCPSLKGSWACCQLPHAVCCE 473
Query: 361 DLRTCCAPGYHC 396
D + CC GY C
Sbjct: 474 DRQHCCPAGYTC 485
Score = 73.2 bits (178), Expect = 3e-13
Identities = 39/131 (29%), Positives = 49/131 (37%)
Frame = +1
Query: 4 TCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVETIDSA 183
+C + SG CC +S V C D HCCP G C K C S+ +
Sbjct: 72 SCLLTVSGTSSCCPFSEGVSCDDGQHCCPRGFHCSADGKSCSQISDSLL----------G 121
Query: 184 KIETPKYTVERSTLREFMIKIGDKNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPD 363
++ P G + CPD TCC+M G +GCCP CC D
Sbjct: 122 AVQCP----------------GSQFECPDSA------TCCIMIDGSWGCCPMPQASCCED 159
Query: 364 LRTCCAPGYHC 396
CC G C
Sbjct: 160 RVHCCPHGASC 170
Score = 51.6 bits (122), Expect = 1e-06
Identities = 22/52 (42%), Positives = 29/52 (55%)
Frame = +1
Query: 253 KNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHCVTGG 408
+++CPDG +C L +G CCPFS GV C D + CC G+HC G
Sbjct: 64 RDHCPDG------YSCLLTVSGTSSCCPFSEGVSCDDGQHCCPRGFHCSADG 109
Score = 51.6 bits (122), Expect = 1e-06
Identities = 18/44 (40%), Positives = 22/44 (50%)
Frame = +1
Query: 4 TCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQ 135
+CC GG CC Y VCC D HCCP G C +C+ +
Sbjct: 527 SCCKDSQGGWACCPYVKGVCCRDGRHCCPIGFHCSAKGTKCLRK 570
>sp|P28799|GRN_HUMAN Granulins precursor (Proepithelin) (PEPI) [Contains: Acrogranin;
Paragranulin; Granulin-1 (Granulin G); Granulin-2
(Granulin F); Granulin-3 (Granulin B); Granulin-4
(Granulin A); Granulin-5 (Granulin C); Granulin-6
(Granulin D); Granulin-7 (Granulin E)]
Length = 593
Score = 104 bits (260), Expect = 1e-22
Identities = 49/133 (36%), Positives = 66/133 (49%)
Frame = +1
Query: 4 TCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVETIDSA 183
TCC SG + CC NA CC D LHCCP+ T CDL+ +C+ + N +
Sbjct: 220 TCCELPSGKYGCCPMPNATCCSDHLHCCPQDTVCDLIQSKCLSKENATTD---------L 270
Query: 184 KIETPKYTVERSTLREFMIKIGDKNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPD 363
+ P +TV +K + +CPDG TCC + +G +GCCPF+ VCC D
Sbjct: 271 LTKLPAHTVGD-------VKCDMEVSCPDG------YTCCRLQSGAWGCCPFTQAVCCED 317
Query: 364 LRTCCAPGYHCVT 402
CC G+ C T
Sbjct: 318 HIHCCPAGFTCDT 330
Score = 97.1 bits (240), Expect = 2e-20
Identities = 48/141 (34%), Positives = 62/141 (43%)
Frame = +1
Query: 4 TCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVETIDSA 183
TCC +SG CC ++ AVCC D +HCCP G TCD C P + P +E +
Sbjct: 295 TCCRLQSGAWGCCPFTQAVCCEDHIHCCPAGFTCDTQKGTC---EQGPHQVPWMEKAPAH 351
Query: 184 KIETPKYTVERSTLREFMIKIGDKNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPD 363
++R C + C TCC + +G +GCCP VCC D
Sbjct: 352 LSLPDPQALKRDV------------PCDNVSSCPSSDTCCQLTSGEWGCCPIPEAVCCSD 399
Query: 364 LRTCCAPGYHCVTGGCA*LGS 426
+ CC GY CV G GS
Sbjct: 400 HQHCCPQGYTCVAEGQCQRGS 420
Score = 92.4 bits (228), Expect = 5e-19
Identities = 46/136 (33%), Positives = 60/136 (44%), Gaps = 1/136 (0%)
Frame = +1
Query: 4 TCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVETIDSA 183
TCC S G CCQ +AVCC D+ HCCP G TC++ + C
Sbjct: 455 TCCPSLGGSWACCQLPHAVCCEDRQHCCPAGYTCNVKARSC------------------- 495
Query: 184 KIETPKYTVERSTLREFMIKIGDKN-NCPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCP 360
E + + +T +G K+ C +G C QTCC + CCP+ GVCC
Sbjct: 496 --EKEVVSAQPATFLARSPHVGVKDVECGEGHFCHDNQTCCRDNRQGWACCPYRQGVCCA 553
Query: 361 DLRTCCAPGYHCVTGG 408
D R CC G+ C G
Sbjct: 554 DRRHCCPAGFRCAARG 569
Score = 89.4 bits (220), Expect = 4e-18
Identities = 47/132 (35%), Positives = 58/132 (43%), Gaps = 1/132 (0%)
Frame = +1
Query: 4 TCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVETIDSA 183
TCC G CC A CC D++HCCP G CDLV+ RCI + T A
Sbjct: 138 TCCVMVDGSWGCCPMPQASCCEDRVHCCPHGAFCDLVHTRCITPTG---------THPLA 188
Query: 184 KIETPKYTVERSTLREFMIKIGD-KNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCP 360
K + P R+ + D ++ CPDG TCC + +G YGCCP CC
Sbjct: 189 K-KLPAQRTNRAVALSSSVMCPDARSRCPDG------STCCELPSGKYGCCPMPNATCCS 241
Query: 361 DLRTCCAPGYHC 396
D CC C
Sbjct: 242 DHLHCCPQDTVC 253
Score = 80.1 bits (196), Expect = 3e-15
Identities = 44/132 (33%), Positives = 54/132 (40%)
Frame = +1
Query: 1 DTCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVETIDS 180
DTCC SG CC AVCC D HCCP+G TC + +C S +V ++
Sbjct: 376 DTCCQLTSGEWGCCPIPEAVCCSDHQHCCPQGYTC-VAEGQCQRGSE------IVAGLEK 428
Query: 181 AKIETPKYTVERSTLREFMIKIGDKNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCP 360
+ R I +CP G QTCC G + CC VCC
Sbjct: 429 MPARRASLSHPRD------IGCDQHTSCPVG------QTCCPSLGGSWACCQLPHAVCCE 476
Query: 361 DLRTCCAPGYHC 396
D + CC GY C
Sbjct: 477 DRQHCCPAGYTC 488
Score = 74.7 bits (182), Expect = 1e-13
Identities = 38/132 (28%), Positives = 47/132 (35%), Gaps = 1/132 (0%)
Frame = +1
Query: 4 TCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVETIDSA 183
+C + SG CC + AV CGD HCCP G C + C +S +
Sbjct: 72 SCIFTVSGTSSCCPFPEAVACGDGHHCCPRGFHCSADGRSCFQRSGNNSVGAI------- 124
Query: 184 KIETPKYTVERSTLREFMIKIGDKNNCPDGG-QCAGLQTCCLMYTGHYGCCPFSLGVCCP 360
CPD +C TCC+M G +GCCP CC
Sbjct: 125 -------------------------QCPDSQFECPDFSTCCVMVDGSWGCCPMPQASCCE 159
Query: 361 DLRTCCAPGYHC 396
D CC G C
Sbjct: 160 DRVHCCPHGAFC 171
Score = 52.0 bits (123), Expect = 8e-07
Identities = 18/44 (40%), Positives = 22/44 (50%)
Frame = +1
Query: 4 TCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQ 135
TCC G CC Y VCC D+ HCCP G C +C+ +
Sbjct: 532 TCCRDNRQGWACCPYRQGVCCADRRHCCPAGFRCAARGTKCLRR 575
Score = 43.9 bits (102), Expect = 2e-04
Identities = 17/49 (34%), Positives = 21/49 (42%)
Frame = +1
Query: 262 CPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHCVTGG 408
C C+ +C +G CCPF V C D CC G+HC G
Sbjct: 61 CQVDAHCSAGHSCIFTVSGTSSCCPFPEAVACGDGHHCCPRGFHCSADG 109
>sp|P28798|GRN_MOUSE Granulins precursor (Acrogranin) (Proepithelin) (PEPI) (PC
cell-derived growth factor) (PCDGF) [Contains: Granulin
1; Granulin 2; Granulin 3; Granulin 4; Granulin 5;
Granulin 6; Granulin 7]
Length = 589
Score = 103 bits (256), Expect = 3e-22
Identities = 49/133 (36%), Positives = 68/133 (51%)
Frame = +1
Query: 4 TCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVETIDSA 183
TCC +G + CC NA+CC D LHCCP+ T CDL+ +C+ ++ T D
Sbjct: 219 TCCELPTGKYGCCPMPNAICCSDHLHCCPQDTVCDLIQSKCLSKN---------YTTD-L 268
Query: 184 KIETPKYTVERSTLREFMIKIGDKNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPD 363
+ P Y V+ +K + +CP+G TCC + TG +GCCPF+ VCC D
Sbjct: 269 LTKLPGYPVKE-------VKCDMEVSCPEG------YTCCRLNTGAWGCCPFAKAVCCED 315
Query: 364 LRTCCAPGYHCVT 402
CC G+ C T
Sbjct: 316 HIHCCPAGFQCHT 328
Score = 98.2 bits (243), Expect = 9e-21
Identities = 50/135 (37%), Positives = 66/135 (48%)
Frame = +1
Query: 4 TCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVETIDSA 183
TCC S G CCQ +AVCC D+ HCCP G TC++ + C + + I+ PV+ T+
Sbjct: 453 TCCPSLKGSWACCQLPHAVCCEDRQHCCPAGYTCNVKARTC-EKDVDFIQPPVLLTLGP- 510
Query: 184 KIETPKYTVERSTLREFMIKIGDKNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPD 363
K+G+ C +G C QTCC G + CCP+ GVCC D
Sbjct: 511 -------------------KVGNVE-CGEGHFCHDNQTCCKDSAGVWACCPYLKGVCCRD 550
Query: 364 LRTCCAPGYHCVTGG 408
R CC G+HC G
Sbjct: 551 GRHCCPGGFHCSARG 565
Score = 90.9 bits (224), Expect = 2e-18
Identities = 45/132 (34%), Positives = 57/132 (43%), Gaps = 1/132 (0%)
Frame = +1
Query: 4 TCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVETIDSA 183
TCC G CC A CC D++HCCP G +CDLV+ RC+ + +
Sbjct: 137 TCCIMVDGSWGCCPMPQASCCEDRVHCCPHGASCDLVHTRCVSPTG----------THTL 186
Query: 184 KIETPKYTVERSTLREFMIKIGD-KNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCP 360
+ P R+ F + D K CPD TCC + TG YGCCP +CC
Sbjct: 187 LKKFPAQKTNRAVSLPFSVVCPDAKTQCPDD------STCCELPTGKYGCCPMPNAICCS 240
Query: 361 DLRTCCAPGYHC 396
D CC C
Sbjct: 241 DHLHCCPQDTVC 252
Score = 89.7 bits (221), Expect = 3e-18
Identities = 42/135 (31%), Positives = 59/135 (43%)
Frame = +1
Query: 4 TCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVETIDSA 183
TCC +G CC ++ AVCC D +HCCP G C H E +++
Sbjct: 293 TCCRLNTGAWGCCPFAKAVCCEDHIHCCPAGFQC--------HTEKGTCEMGILQVPWMK 344
Query: 184 KIETPKYTVERSTLREFMIKIGDKNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPD 363
K+ P + L+ C D +C TCC + +G +GCCP VCC D
Sbjct: 345 KVIAPLRLPDPQILKS-------DTPCDDFTRCPTNNTCCKLNSGDWGCCPIPEAVCCSD 397
Query: 364 LRTCCAPGYHCVTGG 408
+ CC G+ C+ G
Sbjct: 398 NQHCCPQGFTCLAQG 412
Score = 82.8 bits (203), Expect = 4e-16
Identities = 41/131 (31%), Positives = 52/131 (39%)
Frame = +1
Query: 4 TCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVETIDSA 183
+C + SG CC +S V CGD HCCP+G C K C S+ P+
Sbjct: 72 SCLLTVSGTSSCCPFSKGVSCGDGYHCCPQGFHCSADGKSCFQMSDNPL----------G 121
Query: 184 KIETPKYTVERSTLREFMIKIGDKNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPD 363
++ P G + CPD TCC+M G +GCCP CC D
Sbjct: 122 AVQCP----------------GSQFECPDSA------TCCIMVDGSWGCCPMPQASCCED 159
Query: 364 LRTCCAPGYHC 396
CC G C
Sbjct: 160 RVHCCPHGASC 170
Score = 80.9 bits (198), Expect = 2e-15
Identities = 46/133 (34%), Positives = 56/133 (42%), Gaps = 1/133 (0%)
Frame = +1
Query: 1 DTCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVETIDS 180
+TCC SG CC AVCC D HCCP+G TC L C
Sbjct: 374 NTCCKLNSGDWGCCPIPEAVCCSDNQHCCPQGFTC-LAQGYC------------------ 414
Query: 181 AKIETPKYTVERSTLREFM-IKIGDKNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCC 357
K +T +E+ R+ ++IGD C C QTCC G + CC VCC
Sbjct: 415 QKGDTMVAGLEKIPARQTTPLQIGD-IGCDQHTSCPVGQTCCPSLKGSWACCQLPHAVCC 473
Query: 358 PDLRTCCAPGYHC 396
D + CC GY C
Sbjct: 474 EDRQHCCPAGYTC 486
Score = 51.2 bits (121), Expect = 1e-06
Identities = 21/50 (42%), Positives = 25/50 (50%)
Frame = +1
Query: 259 NCPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHCVTGG 408
+C G C +C L +G CCPFS GV C D CC G+HC G
Sbjct: 60 SCQTHGHCPAGYSCLLTVSGTSSCCPFSKGVSCGDGYHCCPQGFHCSADG 109
Score = 50.1 bits (118), Expect = 3e-06
Identities = 18/44 (40%), Positives = 22/44 (50%)
Frame = +1
Query: 4 TCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQ 135
TCC +G CC Y VCC D HCCP G C +C+ +
Sbjct: 528 TCCKDSAGVWACCPYLKGVCCRDGRHCCPGGFHCSARGTKCLRK 571
>sp|P28797|GRN_CAVPO Granulins precursor (Proepithelin) (PEPI) [Contains: Acrogranin;
Granulin-1; Granulin-2; Granulin-3; Granulin-4;
Granulin-5; Granulin-6; Granulin-7]
Length = 591
Score = 102 bits (255), Expect = 4e-22
Identities = 48/133 (36%), Positives = 66/133 (49%)
Frame = +1
Query: 4 TCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVETIDSA 183
TCC SG + CC NA+CC D LHCCP+ T CDL RC+ Q+ +
Sbjct: 220 TCCLLASGEYGCCPMPNAICCSDHLHCCPQDTVCDLRQSRCLSQNK----------AKTL 269
Query: 184 KIETPKYTVERSTLREFMIKIGDKNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPD 363
+ P +TV + ++ + +CP+G QTCC + +G +GCCPF VCC D
Sbjct: 270 LTKLPSWTV-------WDVECDQEVSCPEG------QTCCRLQSGKWGCCPFPKAVCCED 316
Query: 364 LRTCCAPGYHCVT 402
CC + C T
Sbjct: 317 HVHCCPERFRCHT 329
Score = 99.8 bits (247), Expect = 3e-21
Identities = 51/135 (37%), Positives = 63/135 (46%)
Frame = +1
Query: 4 TCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVETIDSA 183
TCC GG CCQ +AVCC D HCCP G TC++ + C + D A
Sbjct: 452 TCCPKLGGGWACCQLPHAVCCEDGQHCCPAGYTCNVKARSC------------EKAADGA 499
Query: 184 KIETPKYTVERSTLREFMIKIGDKNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPD 363
+ P ST + GD++ C D QTCC G + CCPF GVCC D
Sbjct: 500 HLAAP--LAVGSTGGVMDVACGDRHFCHDE------QTCCRDSRGGWACCPFHQGVCCKD 551
Query: 364 LRTCCAPGYHCVTGG 408
R CC G+HC + G
Sbjct: 552 QRHCCPAGFHCESQG 566
Score = 90.1 bits (222), Expect = 3e-18
Identities = 49/137 (35%), Positives = 65/137 (47%), Gaps = 6/137 (4%)
Frame = +1
Query: 4 TCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQ-SNEPI--EWPVVETI 174
TCC G CC A CC D++HCCP G +CDLV+ RC+ + P+ + P T
Sbjct: 124 TCCHMLDGSWGCCPMPQASCCEDRVHCCPHGASCDLVHIRCVTALGSHPLTTKLPAQRTN 183
Query: 175 DSAKIETPKYT--VERSTLREFMIKIGDKNNCPDG-GQCAGLQTCCLMYTGHYGCCPFSL 345
+ TP + + + L +I CPD QC TCCL+ +G YGCCP
Sbjct: 184 YTGAEGTPVVSPGLLPAALPTSVI-------CPDSRSQCPDDTTCCLLASGEYGCCPMPN 236
Query: 346 GVCCPDLRTCCAPGYHC 396
+CC D CC C
Sbjct: 237 AICCSDHLHCCPQDTVC 253
Score = 70.9 bits (172), Expect = 2e-12
Identities = 38/132 (28%), Positives = 50/132 (37%), Gaps = 1/132 (0%)
Frame = +1
Query: 4 TCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVETIDSA 183
+C + +G CC +S A+ CGD HCCP G C CI + P + + +
Sbjct: 58 SCVLTAAGTAACCPFSQAMACGDGHHCCPYGFHCSTDGGTCIQR-------PDIHLLGAV 110
Query: 184 KIETPKYTVERSTLREFMIKIGDKNNCPDGG-QCAGLQTCCLMYTGHYGCCPFSLGVCCP 360
+ CP G +C TCC M G +GCCP CC
Sbjct: 111 Q-------------------------CPGGEFECPDSSTCCHMLDGSWGCCPMPQASCCE 145
Query: 361 DLRTCCAPGYHC 396
D CC G C
Sbjct: 146 DRVHCCPHGASC 157
Score = 63.5 bits (153), Expect = 3e-10
Identities = 34/118 (28%), Positives = 47/118 (39%)
Frame = +1
Query: 4 TCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVETIDSA 183
TCC +SG CC + AVCC D +HCCPE C C Q + W +
Sbjct: 294 TCCRLQSGKWGCCPFPKAVCCEDHVHCCPERFRCHTEKDTC-EQGLLQVPWAQKTPAQPS 352
Query: 184 KIETPKYTVERSTLREFMIKIGDKNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCC 357
+ P + + +C + C CC + +G +GCCP S G C
Sbjct: 353 RPSQPSPPGPPGPPSP-PGPLRSEISCDEVVSCRPGNICCRLASGEWGCCPSSEGYLC 409
Score = 60.5 bits (145), Expect = 2e-09
Identities = 21/46 (45%), Positives = 26/46 (56%)
Frame = +1
Query: 4 TCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSN 141
TCC GG CC + VCC DQ HCCP G C+ RC+H+ +
Sbjct: 529 TCCRDSRGGWACCPFHQGVCCKDQRHCCPAGFHCESQGTRCVHKKS 574
Score = 47.0 bits (110), Expect = 2e-05
Identities = 33/125 (26%), Positives = 50/125 (40%), Gaps = 2/125 (1%)
Frame = +1
Query: 28 GHQCCQYSNAVCCGDQLHCCP--EGTTCDLVNKRCIHQSNEPIEWPVVETIDSAKIETPK 201
G+ CC+ ++ + CCP EG C + +RC V + + K+
Sbjct: 387 GNICCRLASG-----EWGCCPSSEGYLC-MAGERC----------QVGDRLAPEKMAAHL 430
Query: 202 YTVERSTLREFMIKIGDKNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCA 381
++ ++T +G C C QTCC G + CC VCC D + CC
Sbjct: 431 MSLSQTT------DVG----CDQHASCPVRQTCCPKLGGGWACCQLPHAVCCEDGQHCCP 480
Query: 382 PGYHC 396
GY C
Sbjct: 481 AGYTC 485
Score = 46.6 bits (109), Expect = 3e-05
Identities = 21/50 (42%), Positives = 24/50 (48%)
Frame = +1
Query: 259 NCPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHCVTGG 408
NCP G +C L G CCPFS + C D CC G+HC T G
Sbjct: 52 NCPIG------HSCVLTAAGTAACCPFSQAMACGDGHHCCPYGFHCSTDG 95
>sp|P80059|PMD1_LOCMI Pars intercerebralis major peptide D1 (PMP-D1)
Length = 54
Score = 62.0 bits (149), Expect = 7e-10
Identities = 22/43 (51%), Positives = 27/43 (62%)
Frame = +1
Query: 1 DTCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCI 129
+TCC + G CC Y VCC D +HCCP GT CD ++RCI
Sbjct: 11 ETCCTTPQGEEGCCPYKEGVCCLDGIHCCPSGTVCDEDHRRCI 53
Score = 48.9 bits (115), Expect = 7e-06
Identities = 19/39 (48%), Positives = 21/39 (53%)
Frame = +1
Query: 280 CAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHC 396
C G +TCC G GCCP+ GVCC D CC G C
Sbjct: 7 CPGTETCCTTPQGEEGCCPYKEGVCCLDGIHCCPSGTVC 45
>sp|P81013|GRN1_CYPCA Granulin-1
Length = 57
Score = 55.5 bits (132), Expect = 7e-08
Identities = 24/45 (53%), Positives = 26/45 (57%)
Frame = +1
Query: 262 CPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHC 396
CPDG TCCL G + CCPFS+G CC D CC GYHC
Sbjct: 10 CPDG------TTCCLSPYGVWYCCPFSMGQCCRDGIHCCRHGYHC 48
Score = 48.9 bits (115), Expect = 7e-06
Identities = 18/42 (42%), Positives = 22/42 (52%)
Frame = +1
Query: 4 TCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCI 129
TCC S G CC +S CC D +HCC G CD + C+
Sbjct: 15 TCCLSPYGVWYCCPFSMGQCCRDGIHCCRHGYHCDSTSTHCL 56
>sp|P80930|ENA1_HORSE Antimicrobial peptide eNAP-1
Length = 46
Score = 54.3 bits (129), Expect = 2e-07
Identities = 19/31 (61%), Positives = 20/31 (64%)
Frame = +1
Query: 4 TCCASKSGGHQCCQYSNAVCCGDQLHCCPEG 96
TCC + GG CC YS VCC DQ HCCP G
Sbjct: 15 TCCRASQGGXACCPYSQGVCCADQRHCCPVG 45
Score = 53.9 bits (128), Expect = 2e-07
Identities = 21/43 (48%), Positives = 24/43 (55%)
Frame = +1
Query: 262 CPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGY 390
C +G C QTCC G CCP+S GVCC D R CC G+
Sbjct: 4 CGEGHFCHDXQTCCRASQGGXACCPYSQGVCCADQRHCCPVGF 46
>sp|P81015|GRN3_CYPCA Granulin-3
Length = 57
Score = 53.9 bits (128), Expect = 2e-07
Identities = 22/45 (48%), Positives = 24/45 (53%)
Frame = +1
Query: 262 CPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHC 396
C G C TCC G + CCPF +G CC D R CC GYHC
Sbjct: 4 CDAGITCPSGTTCCRSPFGVWYCCPFLMGQCCRDGRHCCRHGYHC 48
Score = 44.3 bits (103), Expect = 2e-04
Identities = 17/42 (40%), Positives = 20/42 (47%)
Frame = +1
Query: 4 TCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCI 129
TCC S G CC + CC D HCC G CD + C+
Sbjct: 15 TCCRSPFGVWYCCPFLMGQCCRDGRHCCRHGYHCDSTSTLCL 56
>sp|P81014|GRN2_CYPCA Granulin-2
Length = 57
Score = 48.9 bits (115), Expect = 7e-06
Identities = 19/39 (48%), Positives = 21/39 (53%)
Frame = +1
Query: 280 CAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHC 396
C TCC G + CCPF +G CC D R CC GY C
Sbjct: 10 CPSRTTCCRSPFGVWYCCPFLMGQCCRDGRHCCRHGYRC 48
Score = 44.7 bits (104), Expect = 1e-04
Identities = 17/42 (40%), Positives = 20/42 (47%)
Frame = +1
Query: 4 TCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCI 129
TCC S G CC + CC D HCC G CD + C+
Sbjct: 15 TCCRSPFGVWYCCPFLMGQCCRDGRHCCRHGYRCDSTSTLCL 56
>sp|P25777|ORYB_ORYSA Oryzain beta chain precursor
Length = 471
Score = 43.5 bits (101), Expect = 3e-04
Identities = 19/50 (38%), Positives = 24/50 (48%), Gaps = 3/50 (6%)
Frame = +1
Query: 250 DKNNCPDGGQCA---GLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGY 390
D +CP G C G + CL++ GCCP CC D +CC P Y
Sbjct: 387 DNFSCPAGSTCCCAFGFRNLCLVW----GCCPVEGATCCKDHASCCPPDY 432
Score = 32.3 bits (72), Expect = 0.64
Identities = 13/39 (33%), Positives = 16/39 (41%), Gaps = 1/39 (2%)
Frame = +1
Query: 37 CCQYSNAVCCGDQLHCC-PEGTTCDLVNKRCIHQSNEPI 150
CC A CC D CC P+ C+ C N P+
Sbjct: 412 CCPVEGATCCKDHASCCPPDYPVCNTRAGTCSASKNSPL 450
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 60,182,893
Number of Sequences: 369166
Number of extensions: 1341370
Number of successful extensions: 4699
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4106
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4609
length of database: 68,354,980
effective HSP length: 102
effective length of database: 49,512,010
effective search space used: 3119256630
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)