Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_010_H02
(171 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P28797|GRN_CAVPO Granulins precursor (Proepithelin) (PEP... 46 3e-05
sp|P81015|GRN3_CYPCA Granulin-3 44 2e-04
sp|P81013|GRN1_CYPCA Granulin-1 43 3e-04
sp|P28798|GRN_MOUSE Granulins precursor (Acrogranin) (Proep... 42 3e-04
sp|P28799|GRN_HUMAN Granulins precursor (Proepithelin) (PEP... 42 4e-04
sp|P23785|GRN_RAT Granulins precursor [Contains: Acrogranin... 42 4e-04
sp|P81014|GRN2_CYPCA Granulin-2 40 0.001
sp|P80930|ENA1_HORSE Antimicrobial peptide eNAP-1 39 0.005
sp|P80059|PMD1_LOCMI Pars intercerebralis major peptide D1 ... 33 0.27
sp|P25777|ORYB_ORYSA Oryzain beta chain precursor 32 0.59
>sp|P28797|GRN_CAVPO Granulins precursor (Proepithelin) (PEPI) [Contains: Acrogranin;
Granulin-1; Granulin-2; Granulin-3; Granulin-4;
Granulin-5; Granulin-6; Granulin-7]
Length = 591
Score = 45.8 bits (107), Expect = 3e-05
Identities = 16/27 (59%), Positives = 18/27 (66%)
Frame = -2
Query: 170 CCPFSLGVCCPDLRTCCAPGYHCVTGG 90
CCPF GVCC D R CC G+HC + G
Sbjct: 540 CCPFHQGVCCKDQRHCCPAGFHCESQG 566
Score = 38.9 bits (89), Expect = 0.004
Identities = 14/27 (51%), Positives = 16/27 (59%)
Frame = -2
Query: 170 CCPFSLGVCCPDLRTCCAPGYHCVTGG 90
CCPFS + C D CC G+HC T G
Sbjct: 69 CCPFSQAMACGDGHHCCPYGFHCSTDG 95
Score = 33.5 bits (75), Expect = 0.16
Identities = 12/25 (48%), Positives = 13/25 (52%)
Frame = -2
Query: 170 CCPFSLGVCCPDLRTCCAPGYHCVT 96
CCPF VCC D CC + C T
Sbjct: 305 CCPFPKAVCCEDHVHCCPERFRCHT 329
Score = 32.0 bits (71), Expect = 0.45
Identities = 11/23 (47%), Positives = 12/23 (52%)
Frame = -2
Query: 170 CCPFSLGVCCPDLRTCCAPGYHC 102
CC VCC D + CC GY C
Sbjct: 463 CCQLPHAVCCEDGQHCCPAGYTC 485
Score = 28.9 bits (63), Expect = 3.8
Identities = 10/23 (43%), Positives = 10/23 (43%)
Frame = -2
Query: 170 CCPFSLGVCCPDLRTCCAPGYHC 102
CCP CC D CC G C
Sbjct: 135 CCPMPQASCCEDRVHCCPHGASC 157
>sp|P81015|GRN3_CYPCA Granulin-3
Length = 57
Score = 43.5 bits (101), Expect = 2e-04
Identities = 15/23 (65%), Positives = 16/23 (69%)
Frame = -2
Query: 170 CCPFSLGVCCPDLRTCCAPGYHC 102
CCPF +G CC D R CC GYHC
Sbjct: 26 CCPFLMGQCCRDGRHCCRHGYHC 48
>sp|P81013|GRN1_CYPCA Granulin-1
Length = 57
Score = 42.7 bits (99), Expect = 3e-04
Identities = 15/23 (65%), Positives = 16/23 (69%)
Frame = -2
Query: 170 CCPFSLGVCCPDLRTCCAPGYHC 102
CCPFS+G CC D CC GYHC
Sbjct: 26 CCPFSMGQCCRDGIHCCRHGYHC 48
Score = 29.6 bits (65), Expect = 2.2
Identities = 12/30 (40%), Positives = 15/30 (50%), Gaps = 3/30 (10%)
Frame = -2
Query: 170 CC--PFSLGVCCP-DLRTCCAPGYHCVTGG 90
CC P+ + CCP + CC G HC G
Sbjct: 16 CCLSPYGVWYCCPFSMGQCCRDGIHCCRHG 45
>sp|P28798|GRN_MOUSE Granulins precursor (Acrogranin) (Proepithelin) (PEPI) (PC
cell-derived growth factor) (PCDGF) [Contains: Granulin
1; Granulin 2; Granulin 3; Granulin 4; Granulin 5;
Granulin 6; Granulin 7]
Length = 589
Score = 42.4 bits (98), Expect = 3e-04
Identities = 15/27 (55%), Positives = 17/27 (62%)
Frame = -2
Query: 170 CCPFSLGVCCPDLRTCCAPGYHCVTGG 90
CCP+ GVCC D R CC G+HC G
Sbjct: 539 CCPYLKGVCCRDGRHCCPGGFHCSARG 565
Score = 40.0 bits (92), Expect = 0.002
Identities = 15/27 (55%), Positives = 16/27 (59%)
Frame = -2
Query: 170 CCPFSLGVCCPDLRTCCAPGYHCVTGG 90
CCPFS GV C D CC G+HC G
Sbjct: 83 CCPFSKGVSCGDGYHCCPQGFHCSADG 109
Score = 37.4 bits (85), Expect = 0.011
Identities = 13/25 (52%), Positives = 15/25 (60%)
Frame = -2
Query: 170 CCPFSLGVCCPDLRTCCAPGYHCVT 96
CCPF+ VCC D CC G+ C T
Sbjct: 304 CCPFAKAVCCEDHIHCCPAGFQCHT 328
Score = 35.8 bits (81), Expect = 0.031
Identities = 12/27 (44%), Positives = 15/27 (55%)
Frame = -2
Query: 170 CCPFSLGVCCPDLRTCCAPGYHCVTGG 90
CCP VCC D + CC G+ C+ G
Sbjct: 386 CCPIPEAVCCSDNQHCCPQGFTCLAQG 412
Score = 32.7 bits (73), Expect = 0.27
Identities = 11/23 (47%), Positives = 12/23 (52%)
Frame = -2
Query: 170 CCPFSLGVCCPDLRTCCAPGYHC 102
CC VCC D + CC GY C
Sbjct: 464 CCQLPHAVCCEDRQHCCPAGYTC 486
Score = 28.9 bits (63), Expect = 3.8
Identities = 10/23 (43%), Positives = 10/23 (43%)
Frame = -2
Query: 170 CCPFSLGVCCPDLRTCCAPGYHC 102
CCP CC D CC G C
Sbjct: 148 CCPMPQASCCEDRVHCCPHGASC 170
>sp|P28799|GRN_HUMAN Granulins precursor (Proepithelin) (PEPI) [Contains: Acrogranin;
Paragranulin; Granulin-1 (Granulin G); Granulin-2
(Granulin F); Granulin-3 (Granulin B); Granulin-4
(Granulin A); Granulin-5 (Granulin C); Granulin-6
(Granulin D); Granulin-7 (Granulin E)]
Length = 593
Score = 42.0 bits (97), Expect = 4e-04
Identities = 14/27 (51%), Positives = 16/27 (59%)
Frame = -2
Query: 170 CCPFSLGVCCPDLRTCCAPGYHCVTGG 90
CCP+ GVCC D R CC G+ C G
Sbjct: 543 CCPYRQGVCCADRRHCCPAGFRCAARG 569
Score = 38.9 bits (89), Expect = 0.004
Identities = 16/33 (48%), Positives = 17/33 (51%)
Frame = -2
Query: 170 CCPFSLGVCCPDLRTCCAPGYHCVTGGCA*LGS 72
CCP VCC D + CC GY CV G GS
Sbjct: 388 CCPIPEAVCCSDHQHCCPQGYTCVAEGQCQRGS 420
Score = 36.6 bits (83), Expect = 0.018
Identities = 13/25 (52%), Positives = 15/25 (60%)
Frame = -2
Query: 170 CCPFSLGVCCPDLRTCCAPGYHCVT 96
CCPF+ VCC D CC G+ C T
Sbjct: 306 CCPFTQAVCCEDHIHCCPAGFTCDT 330
Score = 36.2 bits (82), Expect = 0.024
Identities = 13/27 (48%), Positives = 14/27 (51%)
Frame = -2
Query: 170 CCPFSLGVCCPDLRTCCAPGYHCVTGG 90
CCPF V C D CC G+HC G
Sbjct: 83 CCPFPEAVACGDGHHCCPRGFHCSADG 109
Score = 32.7 bits (73), Expect = 0.27
Identities = 11/23 (47%), Positives = 12/23 (52%)
Frame = -2
Query: 170 CCPFSLGVCCPDLRTCCAPGYHC 102
CC VCC D + CC GY C
Sbjct: 466 CCQLPHAVCCEDRQHCCPAGYTC 488
Score = 28.9 bits (63), Expect = 3.8
Identities = 10/23 (43%), Positives = 10/23 (43%)
Frame = -2
Query: 170 CCPFSLGVCCPDLRTCCAPGYHC 102
CCP CC D CC G C
Sbjct: 149 CCPMPQASCCEDRVHCCPHGAFC 171
>sp|P23785|GRN_RAT Granulins precursor [Contains: Acrogranin; Granulin-1 (Granulin G);
Granulin-2 (Granulin F); Granulin-3 (Granulin B)
(Epithelin-2); Granulin-4 (Granulin A) (Epithelin-1);
Granulin-5 (Granulin C); Granulin-6 (Granulin D);
Granulin-7 (Granulin E)]
Length = 588
Score = 42.0 bits (97), Expect = 4e-04
Identities = 15/27 (55%), Positives = 17/27 (62%)
Frame = -2
Query: 170 CCPFSLGVCCPDLRTCCAPGYHCVTGG 90
CCP+ GVCC D R CC G+HC G
Sbjct: 538 CCPYVKGVCCRDGRHCCPIGFHCSAKG 564
Score = 40.8 bits (94), Expect = 0.001
Identities = 15/27 (55%), Positives = 17/27 (62%)
Frame = -2
Query: 170 CCPFSLGVCCPDLRTCCAPGYHCVTGG 90
CCPFS GV C D + CC G+HC G
Sbjct: 83 CCPFSEGVSCDDGQHCCPRGFHCSADG 109
Score = 37.7 bits (86), Expect = 0.008
Identities = 15/30 (50%), Positives = 17/30 (56%), Gaps = 2/30 (6%)
Frame = -2
Query: 170 CCPFSLGVCCPDLRTCCAPGYHC--VTGGC 87
CCPF+ VCC D CC G+ C TG C
Sbjct: 303 CCPFTKAVCCEDHIHCCPAGFQCHTETGTC 332
Score = 35.0 bits (79), Expect = 0.054
Identities = 12/27 (44%), Positives = 15/27 (55%)
Frame = -2
Query: 170 CCPFSLGVCCPDLRTCCAPGYHCVTGG 90
CCP VCC D + CC G+ C+ G
Sbjct: 385 CCPMPEAVCCLDHQHCCPQGFKCMDEG 411
Score = 32.7 bits (73), Expect = 0.27
Identities = 11/23 (47%), Positives = 12/23 (52%)
Frame = -2
Query: 170 CCPFSLGVCCPDLRTCCAPGYHC 102
CC VCC D + CC GY C
Sbjct: 463 CCQLPHAVCCEDRQHCCPAGYTC 485
Score = 28.9 bits (63), Expect = 3.8
Identities = 10/23 (43%), Positives = 10/23 (43%)
Frame = -2
Query: 170 CCPFSLGVCCPDLRTCCAPGYHC 102
CCP CC D CC G C
Sbjct: 148 CCPMPQASCCEDRVHCCPHGASC 170
>sp|P81014|GRN2_CYPCA Granulin-2
Length = 57
Score = 40.4 bits (93), Expect = 0.001
Identities = 14/23 (60%), Positives = 15/23 (65%)
Frame = -2
Query: 170 CCPFSLGVCCPDLRTCCAPGYHC 102
CCPF +G CC D R CC GY C
Sbjct: 26 CCPFLMGQCCRDGRHCCRHGYRC 48
>sp|P80930|ENA1_HORSE Antimicrobial peptide eNAP-1
Length = 46
Score = 38.5 bits (88), Expect = 0.005
Identities = 13/21 (61%), Positives = 15/21 (71%)
Frame = -2
Query: 170 CCPFSLGVCCPDLRTCCAPGY 108
CCP+S GVCC D R CC G+
Sbjct: 26 CCPYSQGVCCADQRHCCPVGF 46
>sp|P80059|PMD1_LOCMI Pars intercerebralis major peptide D1 (PMP-D1)
Length = 54
Score = 32.7 bits (73), Expect = 0.27
Identities = 12/23 (52%), Positives = 13/23 (56%)
Frame = -2
Query: 170 CCPFSLGVCCPDLRTCCAPGYHC 102
CCP+ GVCC D CC G C
Sbjct: 23 CCPYKEGVCCLDGIHCCPSGTVC 45
>sp|P25777|ORYB_ORYSA Oryzain beta chain precursor
Length = 471
Score = 31.6 bits (70), Expect = 0.59
Identities = 10/21 (47%), Positives = 11/21 (52%)
Frame = -2
Query: 170 CCPFSLGVCCPDLRTCCAPGY 108
CCP CC D +CC P Y
Sbjct: 412 CCPVEGATCCKDHASCCPPDY 432
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,435,119
Number of Sequences: 369166
Number of extensions: 310471
Number of successful extensions: 965
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 886
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 963
length of database: 68,354,980
effective HSP length: 29
effective length of database: 62,997,665
effective search space used: 1700936955
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)