Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_002_J08
(479 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P23785|GRN_RAT Granulins precursor [Contains: Acrogranin... 98 9e-21
sp|P28799|GRN_HUMAN Granulins precursor (Proepithelin) (PEP... 97 1e-20
sp|P28798|GRN_MOUSE Granulins precursor (Acrogranin) (Proep... 96 4e-20
sp|P28797|GRN_CAVPO Granulins precursor (Proepithelin) (PEP... 96 6e-20
sp|P81013|GRN1_CYPCA Granulin-1 55 6e-08
sp|P81015|GRN3_CYPCA Granulin-3 54 2e-07
sp|P80930|ENA1_HORSE Antimicrobial peptide eNAP-1 54 2e-07
sp|P80059|PMD1_LOCMI Pars intercerebralis major peptide D1 ... 52 5e-07
sp|P81014|GRN2_CYPCA Granulin-2 49 6e-06
sp|P25777|ORYB_ORYSA Oryzain beta chain precursor 44 2e-04
>sp|P23785|GRN_RAT Granulins precursor [Contains: Acrogranin; Granulin-1 (Granulin G);
Granulin-2 (Granulin F); Granulin-3 (Granulin B)
(Epithelin-2); Granulin-4 (Granulin A) (Epithelin-1);
Granulin-5 (Granulin C); Granulin-6 (Granulin D);
Granulin-7 (Granulin E)]
Length = 588
Score = 98.2 bits (243), Expect = 9e-21
Identities = 48/132 (36%), Positives = 64/132 (48%), Gaps = 2/132 (1%)
Frame = +1
Query: 4 SGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVETIDSAKIETPK 183
+G + CC NA+CC D LHCCP+ T CDL+ +CI + + + P
Sbjct: 224 TGKYGCCPMPNAICCSDHLHCCPQDTVCDLIQSKCISK----------DYTTDLMTKLPG 273
Query: 184 YTVERSTLREFMIKIGDKNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCA 363
Y V +K + +CPDG TCC + TG +GCCPF+ VCC D CC
Sbjct: 274 YPVNE-------VKCDLEVSCPDG------YTCCRLNTGAWGCCPFTKAVCCEDHIHCCP 320
Query: 364 PGYHC--VTGGC 393
G+ C TG C
Sbjct: 321 AGFQCHTETGTC 332
Score = 85.5 bits (210), Expect = 6e-17
Identities = 45/128 (35%), Positives = 58/128 (45%)
Frame = +1
Query: 7 GGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVETIDSAKIETPKY 186
G CCQ +AVCC D+ HCCP G TC++ + C E
Sbjct: 459 GSWACCQLPHAVCCEDRQHCCPAGYTCNVKARTC---------------------EKDAG 497
Query: 187 TVERSTLREFMIKIGDKNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAP 366
+V+ S F K+G+ C G C Q+CC G + CCP+ GVCC D R CC
Sbjct: 498 SVQPSMDLTFGSKVGNVE-CGAGHFCHDNQSCCKDSQGGWACCPYVKGVCCRDGRHCCPI 556
Query: 367 GYHCVTGG 390
G+HC G
Sbjct: 557 GFHCSAKG 564
Score = 83.6 bits (205), Expect = 2e-16
Identities = 42/124 (33%), Positives = 56/124 (45%)
Frame = +1
Query: 7 GGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVETIDSAKIETPKY 186
G CC A CC D++HCCP G +CDLV+ RCI + P+++ + P
Sbjct: 144 GSWGCCPMPQASCCEDRVHCCPHGASCDLVHTRCISPTG---THPLLK-------KFPAQ 193
Query: 187 TVERSTLREFMIKIGDKNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAP 366
R+ ++ K CPD TCC + TG YGCCP +CC D CC
Sbjct: 194 RTNRAVASFSVVCPDAKTQCPDD------STCCELPTGKYGCCPMPNAICCSDHLHCCPQ 247
Query: 367 GYHC 378
C
Sbjct: 248 DTVC 251
Score = 79.7 bits (195), Expect = 3e-15
Identities = 38/129 (29%), Positives = 59/129 (45%)
Frame = +1
Query: 4 SGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVETIDSAKIETPK 183
+G CC ++ AVCC D +HCCP G C C ++ P ++ + +A + P
Sbjct: 298 TGAWGCCPFTKAVCCEDHIHCCPAGFQCHTETGTC---ELGVLQVPWMKKV-TASLSLPD 353
Query: 184 YTVERSTLREFMIKIGDKNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCA 363
+ ++ + C D C TCC + +G +GCCP VCC D + CC
Sbjct: 354 PQILKNDVP-----------CDDFSSCPSNNTCCRLSSGDWGCCPMPEAVCCLDHQHCCP 402
Query: 364 PGYHCVTGG 390
G+ C+ G
Sbjct: 403 QGFKCMDEG 411
Score = 70.5 bits (171), Expect = 2e-12
Identities = 38/125 (30%), Positives = 46/125 (36%)
Frame = +1
Query: 4 SGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVETIDSAKIETPK 183
SG CC +S V C D HCCP G C K C S+ + ++ P
Sbjct: 78 SGTSSCCPFSEGVSCDDGQHCCPRGFHCSADGKSCSQISDSLL----------GAVQCP- 126
Query: 184 YTVERSTLREFMIKIGDKNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCA 363
G + CPD TCC+M G +GCCP CC D CC
Sbjct: 127 ---------------GSQFECPDSA------TCCIMIDGSWGCCPMPQASCCEDRVHCCP 165
Query: 364 PGYHC 378
G C
Sbjct: 166 HGASC 170
Score = 68.2 bits (165), Expect = 9e-12
Identities = 40/125 (32%), Positives = 50/125 (40%)
Frame = +1
Query: 4 SGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVETIDSAKIETPK 183
SG CC AVCC D HCCP+G C ++ + D K
Sbjct: 380 SGDWGCCPMPEAVCCLDHQHCCPQGFKC--------------MDEGYCQKGDRMVAGLEK 425
Query: 184 YTVERSTLREFMIKIGDKNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCA 363
V ++TL ++ GD C C QTCC G + CC VCC D + CC
Sbjct: 426 MPVRQTTL----LQHGDIG-CDQHTSCPVGQTCCPSLKGSWACCQLPHAVCCEDRQHCCP 480
Query: 364 PGYHC 378
GY C
Sbjct: 481 AGYTC 485
Score = 51.6 bits (122), Expect = 9e-07
Identities = 22/52 (42%), Positives = 29/52 (55%)
Frame = +1
Query: 235 KNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHCVTGG 390
+++CPDG +C L +G CCPFS GV C D + CC G+HC G
Sbjct: 64 RDHCPDG------YSCLLTVSGTSSCCPFSEGVSCDDGQHCCPRGFHCSADG 109
Score = 44.7 bits (104), Expect = 1e-04
Identities = 16/37 (43%), Positives = 19/37 (51%)
Frame = +1
Query: 7 GGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQ 117
GG CC Y VCC D HCCP G C +C+ +
Sbjct: 534 GGWACCPYVKGVCCRDGRHCCPIGFHCSAKGTKCLRK 570
>sp|P28799|GRN_HUMAN Granulins precursor (Proepithelin) (PEPI) [Contains: Acrogranin;
Paragranulin; Granulin-1 (Granulin G); Granulin-2
(Granulin F); Granulin-3 (Granulin B); Granulin-4
(Granulin A); Granulin-5 (Granulin C); Granulin-6
(Granulin D); Granulin-7 (Granulin E)]
Length = 593
Score = 97.4 bits (241), Expect = 1e-20
Identities = 46/127 (36%), Positives = 63/127 (49%)
Frame = +1
Query: 4 SGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVETIDSAKIETPK 183
SG + CC NA CC D LHCCP+ T CDL+ +C+ + N + + P
Sbjct: 226 SGKYGCCPMPNATCCSDHLHCCPQDTVCDLIQSKCLSKENATTD---------LLTKLPA 276
Query: 184 YTVERSTLREFMIKIGDKNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCA 363
+TV +K + +CPDG TCC + +G +GCCPF+ VCC D CC
Sbjct: 277 HTVGD-------VKCDMEVSCPDG------YTCCRLQSGAWGCCPFTQAVCCEDHIHCCP 323
Query: 364 PGYHCVT 384
G+ C T
Sbjct: 324 AGFTCDT 330
Score = 89.4 bits (220), Expect = 4e-18
Identities = 45/136 (33%), Positives = 59/136 (43%)
Frame = +1
Query: 1 KSGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVETIDSAKIETP 180
+SG CC ++ AVCC D +HCCP G TCD C P + P +E +
Sbjct: 300 QSGAWGCCPFTQAVCCEDHIHCCPAGFTCDTQKGTC---EQGPHQVPWMEKAPAHLSLPD 356
Query: 181 KYTVERSTLREFMIKIGDKNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCC 360
++R C + C TCC + +G +GCCP VCC D + CC
Sbjct: 357 PQALKRDV------------PCDNVSSCPSSDTCCQLTSGEWGCCPIPEAVCCSDHQHCC 404
Query: 361 APGYHCVTGGCA*LGS 408
GY CV G GS
Sbjct: 405 PQGYTCVAEGQCQRGS 420
Score = 83.2 bits (204), Expect = 3e-16
Identities = 42/129 (32%), Positives = 56/129 (43%), Gaps = 1/129 (0%)
Frame = +1
Query: 7 GGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVETIDSAKIETPKY 186
G CCQ +AVCC D+ HCCP G TC++ + C E
Sbjct: 462 GSWACCQLPHAVCCEDRQHCCPAGYTCNVKARSC---------------------EKEVV 500
Query: 187 TVERSTLREFMIKIGDKN-NCPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCA 363
+ + +T +G K+ C +G C QTCC + CCP+ GVCC D R CC
Sbjct: 501 SAQPATFLARSPHVGVKDVECGEGHFCHDNQTCCRDNRQGWACCPYRQGVCCADRRHCCP 560
Query: 364 PGYHCVTGG 390
G+ C G
Sbjct: 561 AGFRCAARG 569
Score = 81.6 bits (200), Expect = 8e-16
Identities = 44/125 (35%), Positives = 55/125 (44%), Gaps = 1/125 (0%)
Frame = +1
Query: 7 GGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVETIDSAKIETPKY 186
G CC A CC D++HCCP G CDLV+ RCI + T AK + P
Sbjct: 145 GSWGCCPMPQASCCEDRVHCCPHGAFCDLVHTRCITPTG---------THPLAK-KLPAQ 194
Query: 187 TVERSTLREFMIKIGD-KNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCA 363
R+ + D ++ CPDG TCC + +G YGCCP CC D CC
Sbjct: 195 RTNRAVALSSSVMCPDARSRCPDG------STCCELPSGKYGCCPMPNATCCSDHLHCCP 248
Query: 364 PGYHC 378
C
Sbjct: 249 QDTVC 253
Score = 72.4 bits (176), Expect = 5e-13
Identities = 37/126 (29%), Positives = 44/126 (34%), Gaps = 1/126 (0%)
Frame = +1
Query: 4 SGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVETIDSAKIETPK 183
SG CC + AV CGD HCCP G C + C +S +
Sbjct: 78 SGTSSCCPFPEAVACGDGHHCCPRGFHCSADGRSCFQRSGNNSVGAI------------- 124
Query: 184 YTVERSTLREFMIKIGDKNNCPDGG-QCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCC 360
CPD +C TCC+M G +GCCP CC D CC
Sbjct: 125 -------------------QCPDSQFECPDFSTCCVMVDGSWGCCPMPQASCCEDRVHCC 165
Query: 361 APGYHC 378
G C
Sbjct: 166 PHGAFC 171
Score = 70.5 bits (171), Expect = 2e-12
Identities = 42/125 (33%), Positives = 51/125 (40%)
Frame = +1
Query: 4 SGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVETIDSAKIETPK 183
SG CC AVCC D HCCP+G TC + +C S I + + P
Sbjct: 383 SGEWGCCPIPEAVCCSDHQHCCPQGYTC-VAEGQCQRGSE----------IVAGLEKMPA 431
Query: 184 YTVERSTLREFMIKIGDKNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCA 363
S R+ I +CP G QTCC G + CC VCC D + CC
Sbjct: 432 RRASLSHPRD--IGCDQHTSCPVG------QTCCPSLGGSWACCQLPHAVCCEDRQHCCP 483
Query: 364 PGYHC 378
GY C
Sbjct: 484 AGYTC 488
Score = 44.7 bits (104), Expect = 1e-04
Identities = 15/36 (41%), Positives = 19/36 (52%)
Frame = +1
Query: 10 GHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQ 117
G CC Y VCC D+ HCCP G C +C+ +
Sbjct: 540 GWACCPYRQGVCCADRRHCCPAGFRCAARGTKCLRR 575
Score = 43.9 bits (102), Expect = 2e-04
Identities = 17/49 (34%), Positives = 21/49 (42%)
Frame = +1
Query: 244 CPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHCVTGG 390
C C+ +C +G CCPF V C D CC G+HC G
Sbjct: 61 CQVDAHCSAGHSCIFTVSGTSSCCPFPEAVACGDGHHCCPRGFHCSADG 109
>sp|P28798|GRN_MOUSE Granulins precursor (Acrogranin) (Proepithelin) (PEPI) (PC
cell-derived growth factor) (PCDGF) [Contains: Granulin
1; Granulin 2; Granulin 3; Granulin 4; Granulin 5;
Granulin 6; Granulin 7]
Length = 589
Score = 95.9 bits (237), Expect = 4e-20
Identities = 46/127 (36%), Positives = 65/127 (51%)
Frame = +1
Query: 4 SGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVETIDSAKIETPK 183
+G + CC NA+CC D LHCCP+ T CDL+ +C+ ++ T D + P
Sbjct: 225 TGKYGCCPMPNAICCSDHLHCCPQDTVCDLIQSKCLSKN---------YTTD-LLTKLPG 274
Query: 184 YTVERSTLREFMIKIGDKNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCA 363
Y V+ +K + +CP+G TCC + TG +GCCPF+ VCC D CC
Sbjct: 275 YPVKE-------VKCDMEVSCPEG------YTCCRLNTGAWGCCPFAKAVCCEDHIHCCP 321
Query: 364 PGYHCVT 384
G+ C T
Sbjct: 322 AGFQCHT 328
Score = 89.0 bits (219), Expect = 5e-18
Identities = 46/128 (35%), Positives = 62/128 (48%)
Frame = +1
Query: 7 GGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVETIDSAKIETPKY 186
G CCQ +AVCC D+ HCCP G TC++ + C + + I+ PV+ T+
Sbjct: 460 GSWACCQLPHAVCCEDRQHCCPAGYTCNVKARTC-EKDVDFIQPPVLLTLGP-------- 510
Query: 187 TVERSTLREFMIKIGDKNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAP 366
K+G+ C +G C QTCC G + CCP+ GVCC D R CC
Sbjct: 511 ------------KVGNVE-CGEGHFCHDNQTCCKDSAGVWACCPYLKGVCCRDGRHCCPG 557
Query: 367 GYHCVTGG 390
G+HC G
Sbjct: 558 GFHCSARG 565
Score = 83.6 bits (205), Expect = 2e-16
Identities = 42/125 (33%), Positives = 54/125 (43%), Gaps = 1/125 (0%)
Frame = +1
Query: 7 GGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVETIDSAKIETPKY 186
G CC A CC D++HCCP G +CDLV+ RC+ + + + P
Sbjct: 144 GSWGCCPMPQASCCEDRVHCCPHGASCDLVHTRCVSPTG----------THTLLKKFPAQ 193
Query: 187 TVERSTLREFMIKIGD-KNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCA 363
R+ F + D K CPD TCC + TG YGCCP +CC D CC
Sbjct: 194 KTNRAVSLPFSVVCPDAKTQCPDD------STCCELPTGKYGCCPMPNAICCSDHLHCCP 247
Query: 364 PGYHC 378
C
Sbjct: 248 QDTVC 252
Score = 82.0 bits (201), Expect = 6e-16
Identities = 39/129 (30%), Positives = 56/129 (43%)
Frame = +1
Query: 4 SGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVETIDSAKIETPK 183
+G CC ++ AVCC D +HCCP G C H E +++ K+ P
Sbjct: 299 TGAWGCCPFAKAVCCEDHIHCCPAGFQC--------HTEKGTCEMGILQVPWMKKVIAPL 350
Query: 184 YTVERSTLREFMIKIGDKNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCA 363
+ L+ C D +C TCC + +G +GCCP VCC D + CC
Sbjct: 351 RLPDPQILKS-------DTPCDDFTRCPTNNTCCKLNSGDWGCCPIPEAVCCSDNQHCCP 403
Query: 364 PGYHCVTGG 390
G+ C+ G
Sbjct: 404 QGFTCLAQG 412
Score = 80.1 bits (196), Expect = 2e-15
Identities = 40/125 (32%), Positives = 49/125 (39%)
Frame = +1
Query: 4 SGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVETIDSAKIETPK 183
SG CC +S V CGD HCCP+G C K C S+ P+ ++ P
Sbjct: 78 SGTSSCCPFSKGVSCGDGYHCCPQGFHCSADGKSCFQMSDNPL----------GAVQCP- 126
Query: 184 YTVERSTLREFMIKIGDKNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCA 363
G + CPD TCC+M G +GCCP CC D CC
Sbjct: 127 ---------------GSQFECPDSA------TCCIMVDGSWGCCPMPQASCCEDRVHCCP 165
Query: 364 PGYHC 378
G C
Sbjct: 166 HGASC 170
Score = 72.8 bits (177), Expect = 4e-13
Identities = 43/126 (34%), Positives = 52/126 (41%), Gaps = 1/126 (0%)
Frame = +1
Query: 4 SGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVETIDSAKIETPK 183
SG CC AVCC D HCCP+G TC L C K +T
Sbjct: 381 SGDWGCCPIPEAVCCSDNQHCCPQGFTC-LAQGYC------------------QKGDTMV 421
Query: 184 YTVERSTLREFM-IKIGDKNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCC 360
+E+ R+ ++IGD C C QTCC G + CC VCC D + CC
Sbjct: 422 AGLEKIPARQTTPLQIGDIG-CDQHTSCPVGQTCCPSLKGSWACCQLPHAVCCEDRQHCC 480
Query: 361 APGYHC 378
GY C
Sbjct: 481 PAGYTC 486
Score = 51.2 bits (121), Expect = 1e-06
Identities = 21/50 (42%), Positives = 25/50 (50%)
Frame = +1
Query: 241 NCPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHCVTGG 390
+C G C +C L +G CCPFS GV C D CC G+HC G
Sbjct: 60 SCQTHGHCPAGYSCLLTVSGTSSCCPFSKGVSCGDGYHCCPQGFHCSADG 109
Score = 41.6 bits (96), Expect = 0.001
Identities = 15/38 (39%), Positives = 19/38 (50%)
Frame = +1
Query: 4 SGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQ 117
+G CC Y VCC D HCCP G C +C+ +
Sbjct: 534 AGVWACCPYLKGVCCRDGRHCCPGGFHCSARGTKCLRK 571
>sp|P28797|GRN_CAVPO Granulins precursor (Proepithelin) (PEPI) [Contains: Acrogranin;
Granulin-1; Granulin-2; Granulin-3; Granulin-4;
Granulin-5; Granulin-6; Granulin-7]
Length = 591
Score = 95.5 bits (236), Expect = 6e-20
Identities = 45/127 (35%), Positives = 63/127 (49%)
Frame = +1
Query: 4 SGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVETIDSAKIETPK 183
SG + CC NA+CC D LHCCP+ T CDL RC+ Q+ + + P
Sbjct: 226 SGEYGCCPMPNAICCSDHLHCCPQDTVCDLRQSRCLSQNK----------AKTLLTKLPS 275
Query: 184 YTVERSTLREFMIKIGDKNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCA 363
+TV + ++ + +CP+G QTCC + +G +GCCPF VCC D CC
Sbjct: 276 WTV-------WDVECDQEVSCPEG------QTCCRLQSGKWGCCPFPKAVCCEDHVHCCP 322
Query: 364 PGYHCVT 384
+ C T
Sbjct: 323 ERFRCHT 329
Score = 92.0 bits (227), Expect = 6e-19
Identities = 48/128 (37%), Positives = 60/128 (46%)
Frame = +1
Query: 7 GGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVETIDSAKIETPKY 186
GG CCQ +AVCC D HCCP G TC++ + C + D A + P
Sbjct: 459 GGWACCQLPHAVCCEDGQHCCPAGYTCNVKARSC------------EKAADGAHLAAP-- 504
Query: 187 TVERSTLREFMIKIGDKNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAP 366
ST + GD++ C D QTCC G + CCPF GVCC D R CC
Sbjct: 505 LAVGSTGGVMDVACGDRHFCHDE------QTCCRDSRGGWACCPFHQGVCCKDQRHCCPA 558
Query: 367 GYHCVTGG 390
G+HC + G
Sbjct: 559 GFHCESQG 566
Score = 83.2 bits (204), Expect = 3e-16
Identities = 46/130 (35%), Positives = 62/130 (47%), Gaps = 6/130 (4%)
Frame = +1
Query: 7 GGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQ-SNEPI--EWPVVETIDSAKIET 177
G CC A CC D++HCCP G +CDLV+ RC+ + P+ + P T + T
Sbjct: 131 GSWGCCPMPQASCCEDRVHCCPHGASCDLVHIRCVTALGSHPLTTKLPAQRTNYTGAEGT 190
Query: 178 PKYT--VERSTLREFMIKIGDKNNCPDG-GQCAGLQTCCLMYTGHYGCCPFSLGVCCPDL 348
P + + + L +I CPD QC TCCL+ +G YGCCP +CC D
Sbjct: 191 PVVSPGLLPAALPTSVI-------CPDSRSQCPDDTTCCLLASGEYGCCPMPNAICCSDH 243
Query: 349 RTCCAPGYHC 378
CC C
Sbjct: 244 LHCCPQDTVC 253
Score = 67.8 bits (164), Expect = 1e-11
Identities = 37/126 (29%), Positives = 47/126 (37%), Gaps = 1/126 (0%)
Frame = +1
Query: 4 SGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVETIDSAKIETPK 183
+G CC +S A+ CGD HCCP G C CI + P + + + +
Sbjct: 64 AGTAACCPFSQAMACGDGHHCCPYGFHCSTDGGTCIQR-------PDIHLLGAVQ----- 111
Query: 184 YTVERSTLREFMIKIGDKNNCPDGG-QCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCC 360
CP G +C TCC M G +GCCP CC D CC
Sbjct: 112 --------------------CPGGEFECPDSSTCCHMLDGSWGCCPMPQASCCEDRVHCC 151
Query: 361 APGYHC 378
G C
Sbjct: 152 PHGASC 157
Score = 55.8 bits (133), Expect = 5e-08
Identities = 31/113 (27%), Positives = 44/113 (38%)
Frame = +1
Query: 1 KSGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVETIDSAKIETP 180
+SG CC + AVCC D +HCCPE C C Q + W ++ P
Sbjct: 299 QSGKWGCCPFPKAVCCEDHVHCCPERFRCHTEKDTC-EQGLLQVPWAQKTPAQPSRPSQP 357
Query: 181 KYTVERSTLREFMIKIGDKNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCC 339
+ + +C + C CC + +G +GCCP S G C
Sbjct: 358 SPPGPPGPPSP-PGPLRSEISCDEVVSCRPGNICCRLASGEWGCCPSSEGYLC 409
Score = 52.4 bits (124), Expect = 5e-07
Identities = 18/39 (46%), Positives = 23/39 (58%)
Frame = +1
Query: 7 GGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSN 123
GG CC + VCC DQ HCCP G C+ RC+H+ +
Sbjct: 536 GGWACCPFHQGVCCKDQRHCCPAGFHCESQGTRCVHKKS 574
Score = 47.0 bits (110), Expect = 2e-05
Identities = 33/125 (26%), Positives = 50/125 (40%), Gaps = 2/125 (1%)
Frame = +1
Query: 10 GHQCCQYSNAVCCGDQLHCCP--EGTTCDLVNKRCIHQSNEPIEWPVVETIDSAKIETPK 183
G+ CC+ ++ + CCP EG C + +RC V + + K+
Sbjct: 387 GNICCRLASG-----EWGCCPSSEGYLC-MAGERC----------QVGDRLAPEKMAAHL 430
Query: 184 YTVERSTLREFMIKIGDKNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCA 363
++ ++T +G C C QTCC G + CC VCC D + CC
Sbjct: 431 MSLSQTT------DVG----CDQHASCPVRQTCCPKLGGGWACCQLPHAVCCEDGQHCCP 480
Query: 364 PGYHC 378
GY C
Sbjct: 481 AGYTC 485
Score = 46.6 bits (109), Expect = 3e-05
Identities = 21/50 (42%), Positives = 24/50 (48%)
Frame = +1
Query: 241 NCPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHCVTGG 390
NCP G +C L G CCPFS + C D CC G+HC T G
Sbjct: 52 NCPIG------HSCVLTAAGTAACCPFSQAMACGDGHHCCPYGFHCSTDG 95
>sp|P81013|GRN1_CYPCA Granulin-1
Length = 57
Score = 55.5 bits (132), Expect = 6e-08
Identities = 24/45 (53%), Positives = 26/45 (57%)
Frame = +1
Query: 244 CPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHC 378
CPDG TCCL G + CCPFS+G CC D CC GYHC
Sbjct: 10 CPDG------TTCCLSPYGVWYCCPFSMGQCCRDGIHCCRHGYHC 48
Score = 40.0 bits (92), Expect = 0.003
Identities = 13/31 (41%), Positives = 17/31 (54%)
Frame = +1
Query: 19 CCQYSNAVCCGDQLHCCPEGTTCDLVNKRCI 111
CC +S CC D +HCC G CD + C+
Sbjct: 26 CCPFSMGQCCRDGIHCCRHGYHCDSTSTHCL 56
>sp|P81015|GRN3_CYPCA Granulin-3
Length = 57
Score = 53.9 bits (128), Expect = 2e-07
Identities = 22/45 (48%), Positives = 24/45 (53%)
Frame = +1
Query: 244 CPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHC 378
C G C TCC G + CCPF +G CC D R CC GYHC
Sbjct: 4 CDAGITCPSGTTCCRSPFGVWYCCPFLMGQCCRDGRHCCRHGYHC 48
Score = 35.4 bits (80), Expect = 0.068
Identities = 12/31 (38%), Positives = 15/31 (48%)
Frame = +1
Query: 19 CCQYSNAVCCGDQLHCCPEGTTCDLVNKRCI 111
CC + CC D HCC G CD + C+
Sbjct: 26 CCPFLMGQCCRDGRHCCRHGYHCDSTSTLCL 56
>sp|P80930|ENA1_HORSE Antimicrobial peptide eNAP-1
Length = 46
Score = 53.9 bits (128), Expect = 2e-07
Identities = 21/43 (48%), Positives = 24/43 (55%)
Frame = +1
Query: 244 CPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGY 372
C +G C QTCC G CCP+S GVCC D R CC G+
Sbjct: 4 CGEGHFCHDXQTCCRASQGGXACCPYSQGVCCADQRHCCPVGF 46
Score = 45.4 bits (106), Expect = 7e-05
Identities = 16/24 (66%), Positives = 16/24 (66%)
Frame = +1
Query: 7 GGHQCCQYSNAVCCGDQLHCCPEG 78
GG CC YS VCC DQ HCCP G
Sbjct: 22 GGXACCPYSQGVCCADQRHCCPVG 45
>sp|P80059|PMD1_LOCMI Pars intercerebralis major peptide D1 (PMP-D1)
Length = 54
Score = 52.4 bits (124), Expect = 5e-07
Identities = 19/35 (54%), Positives = 22/35 (62%)
Frame = +1
Query: 7 GGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCI 111
G CC Y VCC D +HCCP GT CD ++RCI
Sbjct: 19 GEEGCCPYKEGVCCLDGIHCCPSGTVCDEDHRRCI 53
Score = 48.9 bits (115), Expect = 6e-06
Identities = 19/39 (48%), Positives = 21/39 (53%)
Frame = +1
Query: 262 CAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHC 378
C G +TCC G GCCP+ GVCC D CC G C
Sbjct: 7 CPGTETCCTTPQGEEGCCPYKEGVCCLDGIHCCPSGTVC 45
>sp|P81014|GRN2_CYPCA Granulin-2
Length = 57
Score = 48.9 bits (115), Expect = 6e-06
Identities = 19/39 (48%), Positives = 21/39 (53%)
Frame = +1
Query: 262 CAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHC 378
C TCC G + CCPF +G CC D R CC GY C
Sbjct: 10 CPSRTTCCRSPFGVWYCCPFLMGQCCRDGRHCCRHGYRC 48
Score = 35.8 bits (81), Expect = 0.052
Identities = 12/31 (38%), Positives = 15/31 (48%)
Frame = +1
Query: 19 CCQYSNAVCCGDQLHCCPEGTTCDLVNKRCI 111
CC + CC D HCC G CD + C+
Sbjct: 26 CCPFLMGQCCRDGRHCCRHGYRCDSTSTLCL 56
>sp|P25777|ORYB_ORYSA Oryzain beta chain precursor
Length = 471
Score = 43.5 bits (101), Expect = 2e-04
Identities = 19/50 (38%), Positives = 24/50 (48%), Gaps = 3/50 (6%)
Frame = +1
Query: 232 DKNNCPDGGQCA---GLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGY 372
D +CP G C G + CL++ GCCP CC D +CC P Y
Sbjct: 387 DNFSCPAGSTCCCAFGFRNLCLVW----GCCPVEGATCCKDHASCCPPDY 432
Score = 32.3 bits (72), Expect = 0.58
Identities = 13/39 (33%), Positives = 16/39 (41%), Gaps = 1/39 (2%)
Frame = +1
Query: 19 CCQYSNAVCCGDQLHCC-PEGTTCDLVNKRCIHQSNEPI 132
CC A CC D CC P+ C+ C N P+
Sbjct: 412 CCPVEGATCCKDHASCCPPDYPVCNTRAGTCSASKNSPL 450
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 58,764,553
Number of Sequences: 369166
Number of extensions: 1295088
Number of successful extensions: 4412
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3948
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4333
length of database: 68,354,980
effective HSP length: 102
effective length of database: 49,512,010
effective search space used: 2822184570
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)