Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_024_A17
(192 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P28797|GRN_CAVPO Granulins precursor (Proepithelin) (PEP... 48 6e-06
sp|P28799|GRN_HUMAN Granulins precursor (Proepithelin) (PEP... 45 7e-05
sp|P81015|GRN3_CYPCA Granulin-3 44 9e-05
sp|P28798|GRN_MOUSE Granulins precursor (Acrogranin) (Proep... 44 9e-05
sp|P23785|GRN_RAT Granulins precursor [Contains: Acrogranin... 44 9e-05
sp|P81013|GRN1_CYPCA Granulin-1 44 2e-04
sp|P81014|GRN2_CYPCA Granulin-2 41 8e-04
sp|P80930|ENA1_HORSE Antimicrobial peptide eNAP-1 40 0.002
sp|P80059|PMD1_LOCMI Pars intercerebralis major peptide D1 ... 37 0.019
sp|P25777|ORYB_ORYSA Oryzain beta chain precursor 35 0.071
>sp|P28797|GRN_CAVPO Granulins precursor (Proepithelin) (PEPI) [Contains: Acrogranin;
Granulin-1; Granulin-2; Granulin-3; Granulin-4;
Granulin-5; Granulin-6; Granulin-7]
Length = 591
Score = 48.1 bits (113), Expect = 6e-06
Identities = 17/31 (54%), Positives = 20/31 (64%)
Frame = +2
Query: 5 GHYGCCPFSLGVCCPDLRTCCAPGYHCVTGG 97
G + CCPF GVCC D R CC G+HC + G
Sbjct: 536 GGWACCPFHQGVCCKDQRHCCPAGFHCESQG 566
Score = 39.7 bits (91), Expect = 0.002
Identities = 15/31 (48%), Positives = 17/31 (54%)
Frame = +2
Query: 5 GHYGCCPFSLGVCCPDLRTCCAPGYHCVTGG 97
G CCPFS + C D CC G+HC T G
Sbjct: 65 GTAACCPFSQAMACGDGHHCCPYGFHCSTDG 95
Score = 38.9 bits (89), Expect = 0.004
Identities = 14/30 (46%), Positives = 17/30 (56%)
Frame = +2
Query: 2 TGHYGCCPFSLGVCCPDLRTCCAPGYHCVT 91
+G +GCCPF VCC D CC + C T
Sbjct: 300 SGKWGCCPFPKAVCCEDHVHCCPERFRCHT 329
Score = 35.0 bits (79), Expect = 0.055
Identities = 12/28 (42%), Positives = 14/28 (50%)
Frame = +2
Query: 2 TGHYGCCPFSLGVCCPDLRTCCAPGYHC 85
+G YGCCP +CC D CC C
Sbjct: 226 SGEYGCCPMPNAICCSDHLHCCPQDTVC 253
Score = 34.3 bits (77), Expect = 0.093
Identities = 12/27 (44%), Positives = 14/27 (51%)
Frame = +2
Query: 5 GHYGCCPFSLGVCCPDLRTCCAPGYHC 85
G + CC VCC D + CC GY C
Sbjct: 459 GGWACCQLPHAVCCEDGQHCCPAGYTC 485
Score = 33.9 bits (76), Expect = 0.12
Identities = 12/27 (44%), Positives = 13/27 (48%)
Frame = +2
Query: 5 GHYGCCPFSLGVCCPDLRTCCAPGYHC 85
G +GCCP CC D CC G C
Sbjct: 131 GSWGCCPMPQASCCEDRVHCCPHGASC 157
>sp|P28799|GRN_HUMAN Granulins precursor (Proepithelin) (PEPI) [Contains: Acrogranin;
Paragranulin; Granulin-1 (Granulin G); Granulin-2
(Granulin F); Granulin-3 (Granulin B); Granulin-4
(Granulin A); Granulin-5 (Granulin C); Granulin-6
(Granulin D); Granulin-7 (Granulin E)]
Length = 593
Score = 44.7 bits (104), Expect = 7e-05
Identities = 18/38 (47%), Positives = 21/38 (55%)
Frame = +2
Query: 2 TGHYGCCPFSLGVCCPDLRTCCAPGYHCVTGGCA*LGS 115
+G +GCCP VCC D + CC GY CV G GS
Sbjct: 383 SGEWGCCPIPEAVCCSDHQHCCPQGYTCVAEGQCQRGS 420
Score = 42.7 bits (99), Expect = 3e-04
Identities = 14/29 (48%), Positives = 17/29 (58%)
Frame = +2
Query: 11 YGCCPFSLGVCCPDLRTCCAPGYHCVTGG 97
+ CCP+ GVCC D R CC G+ C G
Sbjct: 541 WACCPYRQGVCCADRRHCCPAGFRCAARG 569
Score = 41.6 bits (96), Expect = 6e-04
Identities = 15/30 (50%), Positives = 19/30 (63%)
Frame = +2
Query: 2 TGHYGCCPFSLGVCCPDLRTCCAPGYHCVT 91
+G +GCCPF+ VCC D CC G+ C T
Sbjct: 301 SGAWGCCPFTQAVCCEDHIHCCPAGFTCDT 330
Score = 37.4 bits (85), Expect = 0.011
Identities = 14/32 (43%), Positives = 16/32 (50%)
Frame = +2
Query: 2 TGHYGCCPFSLGVCCPDLRTCCAPGYHCVTGG 97
+G CCPF V C D CC G+HC G
Sbjct: 78 SGTSSCCPFPEAVACGDGHHCCPRGFHCSADG 109
Score = 35.4 bits (80), Expect = 0.042
Identities = 12/27 (44%), Positives = 14/27 (51%)
Frame = +2
Query: 5 GHYGCCPFSLGVCCPDLRTCCAPGYHC 85
G + CC VCC D + CC GY C
Sbjct: 462 GSWACCQLPHAVCCEDRQHCCPAGYTC 488
Score = 33.9 bits (76), Expect = 0.12
Identities = 12/27 (44%), Positives = 13/27 (48%)
Frame = +2
Query: 5 GHYGCCPFSLGVCCPDLRTCCAPGYHC 85
G +GCCP CC D CC G C
Sbjct: 145 GSWGCCPMPQASCCEDRVHCCPHGAFC 171
Score = 33.5 bits (75), Expect = 0.16
Identities = 12/28 (42%), Positives = 13/28 (46%)
Frame = +2
Query: 2 TGHYGCCPFSLGVCCPDLRTCCAPGYHC 85
+G YGCCP CC D CC C
Sbjct: 226 SGKYGCCPMPNATCCSDHLHCCPQDTVC 253
>sp|P81015|GRN3_CYPCA Granulin-3
Length = 57
Score = 44.3 bits (103), Expect = 9e-05
Identities = 16/27 (59%), Positives = 18/27 (66%)
Frame = +2
Query: 5 GHYGCCPFSLGVCCPDLRTCCAPGYHC 85
G + CCPF +G CC D R CC GYHC
Sbjct: 22 GVWYCCPFLMGQCCRDGRHCCRHGYHC 48
>sp|P28798|GRN_MOUSE Granulins precursor (Acrogranin) (Proepithelin) (PEPI) (PC
cell-derived growth factor) (PCDGF) [Contains: Granulin
1; Granulin 2; Granulin 3; Granulin 4; Granulin 5;
Granulin 6; Granulin 7]
Length = 589
Score = 44.3 bits (103), Expect = 9e-05
Identities = 16/31 (51%), Positives = 19/31 (61%)
Frame = +2
Query: 5 GHYGCCPFSLGVCCPDLRTCCAPGYHCVTGG 97
G + CCP+ GVCC D R CC G+HC G
Sbjct: 535 GVWACCPYLKGVCCRDGRHCCPGGFHCSARG 565
Score = 43.9 bits (102), Expect = 1e-04
Identities = 16/30 (53%), Positives = 19/30 (63%)
Frame = +2
Query: 2 TGHYGCCPFSLGVCCPDLRTCCAPGYHCVT 91
TG +GCCPF+ VCC D CC G+ C T
Sbjct: 299 TGAWGCCPFAKAVCCEDHIHCCPAGFQCHT 328
Score = 41.2 bits (95), Expect = 8e-04
Identities = 16/32 (50%), Positives = 18/32 (56%)
Frame = +2
Query: 2 TGHYGCCPFSLGVCCPDLRTCCAPGYHCVTGG 97
+G CCPFS GV C D CC G+HC G
Sbjct: 78 SGTSSCCPFSKGVSCGDGYHCCPQGFHCSADG 109
Score = 41.2 bits (95), Expect = 8e-04
Identities = 14/32 (43%), Positives = 19/32 (59%)
Frame = +2
Query: 2 TGHYGCCPFSLGVCCPDLRTCCAPGYHCVTGG 97
+G +GCCP VCC D + CC G+ C+ G
Sbjct: 381 SGDWGCCPIPEAVCCSDNQHCCPQGFTCLAQG 412
Score = 36.2 bits (82), Expect = 0.024
Identities = 13/28 (46%), Positives = 14/28 (50%)
Frame = +2
Query: 2 TGHYGCCPFSLGVCCPDLRTCCAPGYHC 85
TG YGCCP +CC D CC C
Sbjct: 225 TGKYGCCPMPNAICCSDHLHCCPQDTVC 252
Score = 35.4 bits (80), Expect = 0.042
Identities = 12/27 (44%), Positives = 14/27 (51%)
Frame = +2
Query: 5 GHYGCCPFSLGVCCPDLRTCCAPGYHC 85
G + CC VCC D + CC GY C
Sbjct: 460 GSWACCQLPHAVCCEDRQHCCPAGYTC 486
Score = 33.9 bits (76), Expect = 0.12
Identities = 12/27 (44%), Positives = 13/27 (48%)
Frame = +2
Query: 5 GHYGCCPFSLGVCCPDLRTCCAPGYHC 85
G +GCCP CC D CC G C
Sbjct: 144 GSWGCCPMPQASCCEDRVHCCPHGASC 170
>sp|P23785|GRN_RAT Granulins precursor [Contains: Acrogranin; Granulin-1 (Granulin G);
Granulin-2 (Granulin F); Granulin-3 (Granulin B)
(Epithelin-2); Granulin-4 (Granulin A) (Epithelin-1);
Granulin-5 (Granulin C); Granulin-6 (Granulin D);
Granulin-7 (Granulin E)]
Length = 588
Score = 44.3 bits (103), Expect = 9e-05
Identities = 18/35 (51%), Positives = 21/35 (60%), Gaps = 2/35 (5%)
Frame = +2
Query: 2 TGHYGCCPFSLGVCCPDLRTCCAPGYHC--VTGGC 100
TG +GCCPF+ VCC D CC G+ C TG C
Sbjct: 298 TGAWGCCPFTKAVCCEDHIHCCPAGFQCHTETGTC 332
Score = 44.3 bits (103), Expect = 9e-05
Identities = 16/31 (51%), Positives = 19/31 (61%)
Frame = +2
Query: 5 GHYGCCPFSLGVCCPDLRTCCAPGYHCVTGG 97
G + CCP+ GVCC D R CC G+HC G
Sbjct: 534 GGWACCPYVKGVCCRDGRHCCPIGFHCSAKG 564
Score = 42.0 bits (97), Expect = 4e-04
Identities = 16/32 (50%), Positives = 19/32 (59%)
Frame = +2
Query: 2 TGHYGCCPFSLGVCCPDLRTCCAPGYHCVTGG 97
+G CCPFS GV C D + CC G+HC G
Sbjct: 78 SGTSSCCPFSEGVSCDDGQHCCPRGFHCSADG 109
Score = 40.4 bits (93), Expect = 0.001
Identities = 14/32 (43%), Positives = 19/32 (59%)
Frame = +2
Query: 2 TGHYGCCPFSLGVCCPDLRTCCAPGYHCVTGG 97
+G +GCCP VCC D + CC G+ C+ G
Sbjct: 380 SGDWGCCPMPEAVCCLDHQHCCPQGFKCMDEG 411
Score = 36.2 bits (82), Expect = 0.024
Identities = 13/28 (46%), Positives = 14/28 (50%)
Frame = +2
Query: 2 TGHYGCCPFSLGVCCPDLRTCCAPGYHC 85
TG YGCCP +CC D CC C
Sbjct: 224 TGKYGCCPMPNAICCSDHLHCCPQDTVC 251
Score = 35.4 bits (80), Expect = 0.042
Identities = 12/27 (44%), Positives = 14/27 (51%)
Frame = +2
Query: 5 GHYGCCPFSLGVCCPDLRTCCAPGYHC 85
G + CC VCC D + CC GY C
Sbjct: 459 GSWACCQLPHAVCCEDRQHCCPAGYTC 485
Score = 33.9 bits (76), Expect = 0.12
Identities = 12/27 (44%), Positives = 13/27 (48%)
Frame = +2
Query: 5 GHYGCCPFSLGVCCPDLRTCCAPGYHC 85
G +GCCP CC D CC G C
Sbjct: 144 GSWGCCPMPQASCCEDRVHCCPHGASC 170
>sp|P81013|GRN1_CYPCA Granulin-1
Length = 57
Score = 43.5 bits (101), Expect = 2e-04
Identities = 16/27 (59%), Positives = 18/27 (66%)
Frame = +2
Query: 5 GHYGCCPFSLGVCCPDLRTCCAPGYHC 85
G + CCPFS+G CC D CC GYHC
Sbjct: 22 GVWYCCPFSMGQCCRDGIHCCRHGYHC 48
>sp|P81014|GRN2_CYPCA Granulin-2
Length = 57
Score = 41.2 bits (95), Expect = 8e-04
Identities = 15/27 (55%), Positives = 17/27 (62%)
Frame = +2
Query: 5 GHYGCCPFSLGVCCPDLRTCCAPGYHC 85
G + CCPF +G CC D R CC GY C
Sbjct: 22 GVWYCCPFLMGQCCRDGRHCCRHGYRC 48
>sp|P80930|ENA1_HORSE Antimicrobial peptide eNAP-1
Length = 46
Score = 39.7 bits (91), Expect = 0.002
Identities = 14/25 (56%), Positives = 16/25 (64%)
Frame = +2
Query: 5 GHYGCCPFSLGVCCPDLRTCCAPGY 79
G CCP+S GVCC D R CC G+
Sbjct: 22 GGXACCPYSQGVCCADQRHCCPVGF 46
>sp|P80059|PMD1_LOCMI Pars intercerebralis major peptide D1 (PMP-D1)
Length = 54
Score = 36.6 bits (83), Expect = 0.019
Identities = 14/27 (51%), Positives = 15/27 (55%)
Frame = +2
Query: 5 GHYGCCPFSLGVCCPDLRTCCAPGYHC 85
G GCCP+ GVCC D CC G C
Sbjct: 19 GEEGCCPYKEGVCCLDGIHCCPSGTVC 45
>sp|P25777|ORYB_ORYSA Oryzain beta chain precursor
Length = 471
Score = 34.7 bits (78), Expect = 0.071
Identities = 11/23 (47%), Positives = 13/23 (56%)
Frame = +2
Query: 11 YGCCPFSLGVCCPDLRTCCAPGY 79
+GCCP CC D +CC P Y
Sbjct: 410 WGCCPVEGATCCKDHASCCPPDY 432
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 23,342,879
Number of Sequences: 369166
Number of extensions: 390535
Number of successful extensions: 1235
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 1135
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 1232
length of database: 68,354,980
effective HSP length: 35
effective length of database: 61,889,255
effective search space used: 1732899140
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)