Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_012_P09
(225 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P28797|GRN_CAVPO Granulins precursor (Proepithelin) (PEP... 57 1e-08
sp|P28799|GRN_HUMAN Granulins precursor (Proepithelin) (PEP... 55 5e-08
sp|P28798|GRN_MOUSE Granulins precursor (Acrogranin) (Proep... 54 1e-07
sp|P23785|GRN_RAT Granulins precursor [Contains: Acrogranin... 53 2e-07
sp|P81013|GRN1_CYPCA Granulin-1 52 3e-07
sp|P81015|GRN3_CYPCA Granulin-3 51 7e-07
sp|P80930|ENA1_HORSE Antimicrobial peptide eNAP-1 50 2e-06
sp|P81014|GRN2_CYPCA Granulin-2 49 4e-06
sp|P80059|PMD1_LOCMI Pars intercerebralis major peptide D1 ... 49 4e-06
sp|P25777|ORYB_ORYSA Oryzain beta chain precursor 37 0.011
>sp|P28797|GRN_CAVPO Granulins precursor (Proepithelin) (PEPI) [Contains: Acrogranin;
Granulin-1; Granulin-2; Granulin-3; Granulin-4;
Granulin-5; Granulin-6; Granulin-7]
Length = 591
Score = 57.0 bits (136), Expect = 1e-08
Identities = 22/43 (51%), Positives = 25/43 (58%)
Frame = +2
Query: 8 CAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHCVTGG 136
C QTCC G + CCPF GVCC D R CC G+HC + G
Sbjct: 524 CHDEQTCCRDSRGGWACCPFHQGVCCKDQRHCCPAGFHCESQG 566
Score = 50.1 bits (118), Expect = 2e-06
Identities = 19/41 (46%), Positives = 23/41 (56%)
Frame = +2
Query: 8 CAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHCVT 130
C QTCC + +G +GCCPF VCC D CC + C T
Sbjct: 289 CPEGQTCCRLQSGKWGCCPFPKAVCCEDHVHCCPERFRCHT 329
Score = 48.1 bits (113), Expect = 6e-06
Identities = 18/40 (45%), Positives = 21/40 (52%)
Frame = +2
Query: 5 QCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHC 124
QC TCCL+ +G YGCCP +CC D CC C
Sbjct: 214 QCPDDTTCCLLASGEYGCCPMPNAICCSDHLHCCPQDTVC 253
Score = 45.4 bits (106), Expect = 4e-05
Identities = 17/40 (42%), Positives = 19/40 (47%)
Frame = +2
Query: 5 QCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHC 124
+C TCC M G +GCCP CC D CC G C
Sbjct: 118 ECPDSSTCCHMLDGSWGCCPMPQASCCEDRVHCCPHGASC 157
Score = 43.5 bits (101), Expect = 1e-04
Identities = 17/38 (44%), Positives = 20/38 (52%)
Frame = +2
Query: 23 TCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHCVTGG 136
+C L G CCPFS + C D CC G+HC T G
Sbjct: 58 SCVLTAAGTAACCPFSQAMACGDGHHCCPYGFHCSTDG 95
Score = 43.5 bits (101), Expect = 1e-04
Identities = 17/39 (43%), Positives = 19/39 (48%)
Frame = +2
Query: 8 CAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHC 124
C QTCC G + CC VCC D + CC GY C
Sbjct: 447 CPVRQTCCPKLGGGWACCQLPHAVCCEDGQHCCPAGYTC 485
Score = 31.2 bits (69), Expect = 0.76
Identities = 11/26 (42%), Positives = 14/26 (53%)
Frame = +2
Query: 8 CAGLQTCCLMYTGHYGCCPFSLGVCC 85
C CC + +G +GCCP S G C
Sbjct: 384 CRPGNICCRLASGEWGCCPSSEGYLC 409
>sp|P28799|GRN_HUMAN Granulins precursor (Proepithelin) (PEPI) [Contains: Acrogranin;
Paragranulin; Granulin-1 (Granulin G); Granulin-2
(Granulin F); Granulin-3 (Granulin B); Granulin-4
(Granulin A); Granulin-5 (Granulin C); Granulin-6
(Granulin D); Granulin-7 (Granulin E)]
Length = 593
Score = 55.1 bits (131), Expect = 5e-08
Identities = 22/49 (44%), Positives = 26/49 (53%)
Frame = +2
Query: 8 CAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHCVTGGCA*LGS 154
C TCC + +G +GCCP VCC D + CC GY CV G GS
Sbjct: 372 CPSSDTCCQLTSGEWGCCPIPEAVCCSDHQHCCPQGYTCVAEGQCQRGS 420
Score = 50.8 bits (120), Expect = 9e-07
Identities = 19/41 (46%), Positives = 24/41 (58%)
Frame = +2
Query: 8 CAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHCVT 130
C TCC + +G +GCCPF+ VCC D CC G+ C T
Sbjct: 290 CPDGYTCCRLQSGAWGCCPFTQAVCCEDHIHCCPAGFTCDT 330
Score = 50.1 bits (118), Expect = 2e-06
Identities = 19/43 (44%), Positives = 22/43 (51%)
Frame = +2
Query: 8 CAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHCVTGG 136
C QTCC + CCP+ GVCC D R CC G+ C G
Sbjct: 527 CHDNQTCCRDNRQGWACCPYRQGVCCADRRHCCPAGFRCAARG 569
Score = 47.8 bits (112), Expect = 8e-06
Identities = 17/40 (42%), Positives = 20/40 (50%)
Frame = +2
Query: 5 QCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHC 124
+C TCC+M G +GCCP CC D CC G C
Sbjct: 132 ECPDFSTCCVMVDGSWGCCPMPQASCCEDRVHCCPHGAFC 171
Score = 43.9 bits (102), Expect = 1e-04
Identities = 17/39 (43%), Positives = 19/39 (48%)
Frame = +2
Query: 8 CAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHC 124
C QTCC G + CC VCC D + CC GY C
Sbjct: 450 CPVGQTCCPSLGGSWACCQLPHAVCCEDRQHCCPAGYTC 488
Score = 42.4 bits (98), Expect = 3e-04
Identities = 16/43 (37%), Positives = 20/43 (46%)
Frame = +2
Query: 8 CAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHCVTGG 136
C+ +C +G CCPF V C D CC G+HC G
Sbjct: 67 CSAGHSCIFTVSGTSSCCPFPEAVACGDGHHCCPRGFHCSADG 109
Score = 42.4 bits (98), Expect = 3e-04
Identities = 16/40 (40%), Positives = 19/40 (47%)
Frame = +2
Query: 5 QCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHC 124
+C TCC + +G YGCCP CC D CC C
Sbjct: 214 RCPDGSTCCELPSGKYGCCPMPNATCCSDHLHCCPQDTVC 253
>sp|P28798|GRN_MOUSE Granulins precursor (Acrogranin) (Proepithelin) (PEPI) (PC
cell-derived growth factor) (PCDGF) [Contains: Granulin
1; Granulin 2; Granulin 3; Granulin 4; Granulin 5;
Granulin 6; Granulin 7]
Length = 589
Score = 53.5 bits (127), Expect = 1e-07
Identities = 21/43 (48%), Positives = 24/43 (55%)
Frame = +2
Query: 8 CAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHCVTGG 136
C QTCC G + CCP+ GVCC D R CC G+HC G
Sbjct: 523 CHDNQTCCKDSAGVWACCPYLKGVCCRDGRHCCPGGFHCSARG 565
Score = 52.4 bits (124), Expect = 3e-07
Identities = 20/41 (48%), Positives = 24/41 (58%)
Frame = +2
Query: 8 CAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHCVT 130
C TCC + TG +GCCPF+ VCC D CC G+ C T
Sbjct: 288 CPEGYTCCRLNTGAWGCCPFAKAVCCEDHIHCCPAGFQCHT 328
Score = 50.8 bits (120), Expect = 9e-07
Identities = 18/44 (40%), Positives = 25/44 (56%)
Frame = +2
Query: 5 QCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHCVTGG 136
+C TCC + +G +GCCP VCC D + CC G+ C+ G
Sbjct: 369 RCPTNNTCCKLNSGDWGCCPIPEAVCCSDNQHCCPQGFTCLAQG 412
Score = 48.9 bits (115), Expect = 4e-06
Identities = 20/45 (44%), Positives = 23/45 (51%)
Frame = +2
Query: 2 GQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHCVTGG 136
G C +C L +G CCPFS GV C D CC G+HC G
Sbjct: 65 GHCPAGYSCLLTVSGTSSCCPFSKGVSCGDGYHCCPQGFHCSADG 109
Score = 47.0 bits (110), Expect = 1e-05
Identities = 17/40 (42%), Positives = 20/40 (50%)
Frame = +2
Query: 5 QCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHC 124
+C TCC+M G +GCCP CC D CC G C
Sbjct: 131 ECPDSATCCIMVDGSWGCCPMPQASCCEDRVHCCPHGASC 170
Score = 46.6 bits (109), Expect = 2e-05
Identities = 18/40 (45%), Positives = 20/40 (50%)
Frame = +2
Query: 5 QCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHC 124
QC TCC + TG YGCCP +CC D CC C
Sbjct: 213 QCPDDSTCCELPTGKYGCCPMPNAICCSDHLHCCPQDTVC 252
Score = 44.3 bits (103), Expect = 9e-05
Identities = 17/39 (43%), Positives = 19/39 (48%)
Frame = +2
Query: 8 CAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHC 124
C QTCC G + CC VCC D + CC GY C
Sbjct: 448 CPVGQTCCPSLKGSWACCQLPHAVCCEDRQHCCPAGYTC 486
>sp|P23785|GRN_RAT Granulins precursor [Contains: Acrogranin; Granulin-1 (Granulin G);
Granulin-2 (Granulin F); Granulin-3 (Granulin B)
(Epithelin-2); Granulin-4 (Granulin A) (Epithelin-1);
Granulin-5 (Granulin C); Granulin-6 (Granulin D);
Granulin-7 (Granulin E)]
Length = 588
Score = 53.1 bits (126), Expect = 2e-07
Identities = 22/46 (47%), Positives = 26/46 (56%), Gaps = 2/46 (4%)
Frame = +2
Query: 8 CAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHC--VTGGC 139
C TCC + TG +GCCPF+ VCC D CC G+ C TG C
Sbjct: 287 CPDGYTCCRLNTGAWGCCPFTKAVCCEDHIHCCPAGFQCHTETGTC 332
Score = 51.6 bits (122), Expect = 5e-07
Identities = 20/43 (46%), Positives = 24/43 (55%)
Frame = +2
Query: 8 CAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHCVTGG 136
C Q+CC G + CCP+ GVCC D R CC G+HC G
Sbjct: 522 CHDNQSCCKDSQGGWACCPYVKGVCCRDGRHCCPIGFHCSAKG 564
Score = 50.4 bits (119), Expect = 1e-06
Identities = 18/43 (41%), Positives = 24/43 (55%)
Frame = +2
Query: 8 CAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHCVTGG 136
C TCC + +G +GCCP VCC D + CC G+ C+ G
Sbjct: 369 CPSNNTCCRLSSGDWGCCPMPEAVCCLDHQHCCPQGFKCMDEG 411
Score = 47.0 bits (110), Expect = 1e-05
Identities = 19/43 (44%), Positives = 23/43 (53%)
Frame = +2
Query: 8 CAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHCVTGG 136
C +C L +G CCPFS GV C D + CC G+HC G
Sbjct: 67 CPDGYSCLLTVSGTSSCCPFSEGVSCDDGQHCCPRGFHCSADG 109
Score = 47.0 bits (110), Expect = 1e-05
Identities = 17/40 (42%), Positives = 20/40 (50%)
Frame = +2
Query: 5 QCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHC 124
+C TCC+M G +GCCP CC D CC G C
Sbjct: 131 ECPDSATCCIMIDGSWGCCPMPQASCCEDRVHCCPHGASC 170
Score = 46.6 bits (109), Expect = 2e-05
Identities = 18/40 (45%), Positives = 20/40 (50%)
Frame = +2
Query: 5 QCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHC 124
QC TCC + TG YGCCP +CC D CC C
Sbjct: 212 QCPDDSTCCELPTGKYGCCPMPNAICCSDHLHCCPQDTVC 251
Score = 44.3 bits (103), Expect = 9e-05
Identities = 17/39 (43%), Positives = 19/39 (48%)
Frame = +2
Query: 8 CAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHC 124
C QTCC G + CC VCC D + CC GY C
Sbjct: 447 CPVGQTCCPSLKGSWACCQLPHAVCCEDRQHCCPAGYTC 485
>sp|P81013|GRN1_CYPCA Granulin-1
Length = 57
Score = 52.4 bits (124), Expect = 3e-07
Identities = 21/39 (53%), Positives = 23/39 (58%)
Frame = +2
Query: 8 CAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHC 124
C TCCL G + CCPFS+G CC D CC GYHC
Sbjct: 10 CPDGTTCCLSPYGVWYCCPFSMGQCCRDGIHCCRHGYHC 48
>sp|P81015|GRN3_CYPCA Granulin-3
Length = 57
Score = 51.2 bits (121), Expect = 7e-07
Identities = 20/39 (51%), Positives = 22/39 (56%)
Frame = +2
Query: 8 CAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHC 124
C TCC G + CCPF +G CC D R CC GYHC
Sbjct: 10 CPSGTTCCRSPFGVWYCCPFLMGQCCRDGRHCCRHGYHC 48
>sp|P80930|ENA1_HORSE Antimicrobial peptide eNAP-1
Length = 46
Score = 50.1 bits (118), Expect = 2e-06
Identities = 19/37 (51%), Positives = 21/37 (56%)
Frame = +2
Query: 8 CAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGY 118
C QTCC G CCP+S GVCC D R CC G+
Sbjct: 10 CHDXQTCCRASQGGXACCPYSQGVCCADQRHCCPVGF 46
>sp|P81014|GRN2_CYPCA Granulin-2
Length = 57
Score = 48.9 bits (115), Expect = 4e-06
Identities = 19/39 (48%), Positives = 21/39 (53%)
Frame = +2
Query: 8 CAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHC 124
C TCC G + CCPF +G CC D R CC GY C
Sbjct: 10 CPSRTTCCRSPFGVWYCCPFLMGQCCRDGRHCCRHGYRC 48
>sp|P80059|PMD1_LOCMI Pars intercerebralis major peptide D1 (PMP-D1)
Length = 54
Score = 48.9 bits (115), Expect = 4e-06
Identities = 19/39 (48%), Positives = 21/39 (53%)
Frame = +2
Query: 8 CAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHC 124
C G +TCC G GCCP+ GVCC D CC G C
Sbjct: 7 CPGTETCCTTPQGEEGCCPYKEGVCCLDGIHCCPSGTVC 45
>sp|P25777|ORYB_ORYSA Oryzain beta chain precursor
Length = 471
Score = 37.4 bits (85), Expect = 0.011
Identities = 15/42 (35%), Positives = 18/42 (42%), Gaps = 5/42 (11%)
Frame = +2
Query: 8 CAGLQTCCLMYTGH-----YGCCPFSLGVCCPDLRTCCAPGY 118
C TCC + +GCCP CC D +CC P Y
Sbjct: 391 CPAGSTCCCAFGFRNLCLVWGCCPVEGATCCKDHASCCPPDY 432
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 28,309,616
Number of Sequences: 369166
Number of extensions: 546168
Number of successful extensions: 1600
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 1469
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 1589
length of database: 68,354,980
effective HSP length: 46
effective length of database: 59,857,170
effective search space used: 1676000760
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)