Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_001_A11
(221 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P28797|GRN_CAVPO Granulins precursor (Proepithelin) (PEP... 57 1e-08
sp|P28799|GRN_HUMAN Granulins precursor (Proepithelin) (PEP... 55 4e-08
sp|P28798|GRN_MOUSE Granulins precursor (Acrogranin) (Proep... 54 1e-07
sp|P23785|GRN_RAT Granulins precursor [Contains: Acrogranin... 54 1e-07
sp|P81015|GRN3_CYPCA Granulin-3 53 2e-07
sp|P81013|GRN1_CYPCA Granulin-1 52 3e-07
sp|P81014|GRN2_CYPCA Granulin-2 51 9e-07
sp|P80059|PMD1_LOCMI Pars intercerebralis major peptide D1 ... 51 9e-07
sp|P80930|ENA1_HORSE Antimicrobial peptide eNAP-1 50 2e-06
sp|P25776|ORYA_ORYSA Oryzain alpha chain precursor 39 0.004
>sp|P28797|GRN_CAVPO Granulins precursor (Proepithelin) (PEPI) [Contains: Acrogranin;
Granulin-1; Granulin-2; Granulin-3; Granulin-4;
Granulin-5; Granulin-6; Granulin-7]
Length = 591
Score = 57.0 bits (136), Expect = 1e-08
Identities = 22/43 (51%), Positives = 25/43 (58%)
Frame = +1
Query: 4 CAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHCVTGG 132
C QTCC G + CCPF GVCC D R CC G+HC + G
Sbjct: 524 CHDEQTCCRDSRGGWACCPFHQGVCCKDQRHCCPAGFHCESQG 566
Score = 50.4 bits (119), Expect = 1e-06
Identities = 19/42 (45%), Positives = 24/42 (57%)
Frame = +1
Query: 1 TCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHCVT 126
+C QTCC + +G +GCCPF VCC D CC + C T
Sbjct: 288 SCPEGQTCCRLQSGKWGCCPFPKAVCCEDHVHCCPERFRCHT 329
Score = 46.2 bits (108), Expect = 2e-05
Identities = 17/39 (43%), Positives = 20/39 (51%)
Frame = +1
Query: 4 CAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHC 120
C TCCL+ +G YGCCP +CC D CC C
Sbjct: 215 CPDDTTCCLLASGEYGCCPMPNAICCSDHLHCCPQDTVC 253
Score = 44.7 bits (104), Expect = 7e-05
Identities = 17/39 (43%), Positives = 18/39 (46%)
Frame = +1
Query: 4 CAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHC 120
C TCC M G +GCCP CC D CC G C
Sbjct: 119 CPDSSTCCHMLDGSWGCCPMPQASCCEDRVHCCPHGASC 157
Score = 43.9 bits (102), Expect = 1e-04
Identities = 17/40 (42%), Positives = 20/40 (50%)
Frame = +1
Query: 1 TCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHC 120
+C QTCC G + CC VCC D + CC GY C
Sbjct: 446 SCPVRQTCCPKLGGGWACCQLPHAVCCEDGQHCCPAGYTC 485
Score = 43.5 bits (101), Expect = 1e-04
Identities = 17/38 (44%), Positives = 20/38 (52%)
Frame = +1
Query: 19 TCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHCVTGG 132
+C L G CCPFS + C D CC G+HC T G
Sbjct: 58 SCVLTAAGTAACCPFSQAMACGDGHHCCPYGFHCSTDG 95
Score = 31.6 bits (70), Expect = 0.59
Identities = 11/27 (40%), Positives = 15/27 (55%)
Frame = +1
Query: 1 TCAGLQTCCLMYTGHYGCCPFSLGVCC 81
+C CC + +G +GCCP S G C
Sbjct: 383 SCRPGNICCRLASGEWGCCPSSEGYLC 409
>sp|P28799|GRN_HUMAN Granulins precursor (Proepithelin) (PEPI) [Contains: Acrogranin;
Paragranulin; Granulin-1 (Granulin G); Granulin-2
(Granulin F); Granulin-3 (Granulin B); Granulin-4
(Granulin A); Granulin-5 (Granulin C); Granulin-6
(Granulin D); Granulin-7 (Granulin E)]
Length = 593
Score = 55.5 bits (132), Expect = 4e-08
Identities = 22/50 (44%), Positives = 27/50 (54%)
Frame = +1
Query: 1 TCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHCVTGGCA*LGS 150
+C TCC + +G +GCCP VCC D + CC GY CV G GS
Sbjct: 371 SCPSSDTCCQLTSGEWGCCPIPEAVCCSDHQHCCPQGYTCVAEGQCQRGS 420
Score = 51.2 bits (121), Expect = 7e-07
Identities = 19/42 (45%), Positives = 25/42 (59%)
Frame = +1
Query: 1 TCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHCVT 126
+C TCC + +G +GCCPF+ VCC D CC G+ C T
Sbjct: 289 SCPDGYTCCRLQSGAWGCCPFTQAVCCEDHIHCCPAGFTCDT 330
Score = 50.1 bits (118), Expect = 2e-06
Identities = 19/43 (44%), Positives = 22/43 (51%)
Frame = +1
Query: 4 CAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHCVTGG 132
C QTCC + CCP+ GVCC D R CC G+ C G
Sbjct: 527 CHDNQTCCRDNRQGWACCPYRQGVCCADRRHCCPAGFRCAARG 569
Score = 47.0 bits (110), Expect = 1e-05
Identities = 17/39 (43%), Positives = 19/39 (48%)
Frame = +1
Query: 4 CAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHC 120
C TCC+M G +GCCP CC D CC G C
Sbjct: 133 CPDFSTCCVMVDGSWGCCPMPQASCCEDRVHCCPHGAFC 171
Score = 44.3 bits (103), Expect = 9e-05
Identities = 17/40 (42%), Positives = 20/40 (50%)
Frame = +1
Query: 1 TCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHC 120
+C QTCC G + CC VCC D + CC GY C
Sbjct: 449 SCPVGQTCCPSLGGSWACCQLPHAVCCEDRQHCCPAGYTC 488
Score = 42.4 bits (98), Expect = 3e-04
Identities = 16/43 (37%), Positives = 20/43 (46%)
Frame = +1
Query: 4 CAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHCVTGG 132
C+ +C +G CCPF V C D CC G+HC G
Sbjct: 67 CSAGHSCIFTVSGTSSCCPFPEAVACGDGHHCCPRGFHCSADG 109
Score = 42.0 bits (97), Expect = 4e-04
Identities = 16/39 (41%), Positives = 18/39 (46%)
Frame = +1
Query: 4 CAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHC 120
C TCC + +G YGCCP CC D CC C
Sbjct: 215 CPDGSTCCELPSGKYGCCPMPNATCCSDHLHCCPQDTVC 253
>sp|P28798|GRN_MOUSE Granulins precursor (Acrogranin) (Proepithelin) (PEPI) (PC
cell-derived growth factor) (PCDGF) [Contains: Granulin
1; Granulin 2; Granulin 3; Granulin 4; Granulin 5;
Granulin 6; Granulin 7]
Length = 589
Score = 53.5 bits (127), Expect = 1e-07
Identities = 21/43 (48%), Positives = 24/43 (55%)
Frame = +1
Query: 4 CAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHCVTGG 132
C QTCC G + CCP+ GVCC D R CC G+HC G
Sbjct: 523 CHDNQTCCKDSAGVWACCPYLKGVCCRDGRHCCPGGFHCSARG 565
Score = 52.8 bits (125), Expect = 2e-07
Identities = 20/42 (47%), Positives = 25/42 (59%)
Frame = +1
Query: 1 TCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHCVT 126
+C TCC + TG +GCCPF+ VCC D CC G+ C T
Sbjct: 287 SCPEGYTCCRLNTGAWGCCPFAKAVCCEDHIHCCPAGFQCHT 328
Score = 50.4 bits (119), Expect = 1e-06
Identities = 18/43 (41%), Positives = 24/43 (55%)
Frame = +1
Query: 4 CAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHCVTGG 132
C TCC + +G +GCCP VCC D + CC G+ C+ G
Sbjct: 370 CPTNNTCCKLNSGDWGCCPIPEAVCCSDNQHCCPQGFTCLAQG 412
Score = 46.6 bits (109), Expect = 2e-05
Identities = 19/43 (44%), Positives = 22/43 (51%)
Frame = +1
Query: 4 CAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHCVTGG 132
C +C L +G CCPFS GV C D CC G+HC G
Sbjct: 67 CPAGYSCLLTVSGTSSCCPFSKGVSCGDGYHCCPQGFHCSADG 109
Score = 46.2 bits (108), Expect = 2e-05
Identities = 17/39 (43%), Positives = 19/39 (48%)
Frame = +1
Query: 4 CAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHC 120
C TCC+M G +GCCP CC D CC G C
Sbjct: 132 CPDSATCCIMVDGSWGCCPMPQASCCEDRVHCCPHGASC 170
Score = 44.7 bits (104), Expect = 7e-05
Identities = 17/39 (43%), Positives = 19/39 (48%)
Frame = +1
Query: 4 CAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHC 120
C TCC + TG YGCCP +CC D CC C
Sbjct: 214 CPDDSTCCELPTGKYGCCPMPNAICCSDHLHCCPQDTVC 252
Score = 44.7 bits (104), Expect = 7e-05
Identities = 17/40 (42%), Positives = 20/40 (50%)
Frame = +1
Query: 1 TCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHC 120
+C QTCC G + CC VCC D + CC GY C
Sbjct: 447 SCPVGQTCCPSLKGSWACCQLPHAVCCEDRQHCCPAGYTC 486
>sp|P23785|GRN_RAT Granulins precursor [Contains: Acrogranin; Granulin-1 (Granulin G);
Granulin-2 (Granulin F); Granulin-3 (Granulin B)
(Epithelin-2); Granulin-4 (Granulin A) (Epithelin-1);
Granulin-5 (Granulin C); Granulin-6 (Granulin D);
Granulin-7 (Granulin E)]
Length = 588
Score = 53.5 bits (127), Expect = 1e-07
Identities = 22/47 (46%), Positives = 27/47 (57%), Gaps = 2/47 (4%)
Frame = +1
Query: 1 TCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHC--VTGGC 135
+C TCC + TG +GCCPF+ VCC D CC G+ C TG C
Sbjct: 286 SCPDGYTCCRLNTGAWGCCPFTKAVCCEDHIHCCPAGFQCHTETGTC 332
Score = 51.6 bits (122), Expect = 5e-07
Identities = 20/43 (46%), Positives = 24/43 (55%)
Frame = +1
Query: 4 CAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHCVTGG 132
C Q+CC G + CCP+ GVCC D R CC G+HC G
Sbjct: 522 CHDNQSCCKDSQGGWACCPYVKGVCCRDGRHCCPIGFHCSAKG 564
Score = 50.8 bits (120), Expect = 9e-07
Identities = 18/44 (40%), Positives = 25/44 (56%)
Frame = +1
Query: 1 TCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHCVTGG 132
+C TCC + +G +GCCP VCC D + CC G+ C+ G
Sbjct: 368 SCPSNNTCCRLSSGDWGCCPMPEAVCCLDHQHCCPQGFKCMDEG 411
Score = 47.0 bits (110), Expect = 1e-05
Identities = 19/43 (44%), Positives = 23/43 (53%)
Frame = +1
Query: 4 CAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHCVTGG 132
C +C L +G CCPFS GV C D + CC G+HC G
Sbjct: 67 CPDGYSCLLTVSGTSSCCPFSEGVSCDDGQHCCPRGFHCSADG 109
Score = 46.2 bits (108), Expect = 2e-05
Identities = 17/39 (43%), Positives = 19/39 (48%)
Frame = +1
Query: 4 CAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHC 120
C TCC+M G +GCCP CC D CC G C
Sbjct: 132 CPDSATCCIMIDGSWGCCPMPQASCCEDRVHCCPHGASC 170
Score = 44.7 bits (104), Expect = 7e-05
Identities = 17/39 (43%), Positives = 19/39 (48%)
Frame = +1
Query: 4 CAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHC 120
C TCC + TG YGCCP +CC D CC C
Sbjct: 213 CPDDSTCCELPTGKYGCCPMPNAICCSDHLHCCPQDTVC 251
Score = 44.7 bits (104), Expect = 7e-05
Identities = 17/40 (42%), Positives = 20/40 (50%)
Frame = +1
Query: 1 TCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHC 120
+C QTCC G + CC VCC D + CC GY C
Sbjct: 446 SCPVGQTCCPSLKGSWACCQLPHAVCCEDRQHCCPAGYTC 485
>sp|P81015|GRN3_CYPCA Granulin-3
Length = 57
Score = 53.1 bits (126), Expect = 2e-07
Identities = 21/40 (52%), Positives = 23/40 (57%)
Frame = +1
Query: 1 TCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHC 120
TC TCC G + CCPF +G CC D R CC GYHC
Sbjct: 9 TCPSGTTCCRSPFGVWYCCPFLMGQCCRDGRHCCRHGYHC 48
>sp|P81013|GRN1_CYPCA Granulin-1
Length = 57
Score = 52.4 bits (124), Expect = 3e-07
Identities = 21/39 (53%), Positives = 23/39 (58%)
Frame = +1
Query: 4 CAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHC 120
C TCCL G + CCPFS+G CC D CC GYHC
Sbjct: 10 CPDGTTCCLSPYGVWYCCPFSMGQCCRDGIHCCRHGYHC 48
>sp|P81014|GRN2_CYPCA Granulin-2
Length = 57
Score = 50.8 bits (120), Expect = 9e-07
Identities = 20/40 (50%), Positives = 22/40 (55%)
Frame = +1
Query: 1 TCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHC 120
TC TCC G + CCPF +G CC D R CC GY C
Sbjct: 9 TCPSRTTCCRSPFGVWYCCPFLMGQCCRDGRHCCRHGYRC 48
>sp|P80059|PMD1_LOCMI Pars intercerebralis major peptide D1 (PMP-D1)
Length = 54
Score = 50.8 bits (120), Expect = 9e-07
Identities = 20/40 (50%), Positives = 22/40 (55%)
Frame = +1
Query: 1 TCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHC 120
TC G +TCC G GCCP+ GVCC D CC G C
Sbjct: 6 TCPGTETCCTTPQGEEGCCPYKEGVCCLDGIHCCPSGTVC 45
>sp|P80930|ENA1_HORSE Antimicrobial peptide eNAP-1
Length = 46
Score = 50.1 bits (118), Expect = 2e-06
Identities = 19/37 (51%), Positives = 21/37 (56%)
Frame = +1
Query: 4 CAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGY 114
C QTCC G CCP+S GVCC D R CC G+
Sbjct: 10 CHDXQTCCRASQGGXACCPYSQGVCCADQRHCCPVGF 46
>sp|P25776|ORYA_ORYSA Oryzain alpha chain precursor
Length = 458
Score = 38.9 bits (89), Expect = 0.004
Identities = 18/43 (41%), Positives = 20/43 (46%), Gaps = 5/43 (11%)
Frame = +1
Query: 1 TCAGLQTCCLMYT-GHY----GCCPFSLGVCCPDLRTCCAPGY 114
TC TCC +Y G Y GCCP CC D +CC Y
Sbjct: 372 TCPDSTTCCCIYEYGKYCYAWGCCPLEGATCCDDHYSCCPHEY 414
Score = 27.7 bits (60), Expect = 8.4
Identities = 11/27 (40%), Positives = 12/27 (44%)
Frame = +1
Query: 19 TCCLMYTGHYGCCPFSLGVCCPDLRTC 99
TCC HY CCP +C TC
Sbjct: 401 TCC---DDHYSCCPHEYPICNVQQGTC 424
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 27,734,695
Number of Sequences: 369166
Number of extensions: 529124
Number of successful extensions: 1518
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 1389
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 1508
length of database: 68,354,980
effective HSP length: 45
effective length of database: 60,041,905
effective search space used: 1681173340
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)