Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_011_J14
(459 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P23785|GRN_RAT Granulins precursor [Contains: Acrogranin... 91 2e-18
sp|P28799|GRN_HUMAN Granulins precursor (Proepithelin) (PEP... 89 6e-18
sp|P28798|GRN_MOUSE Granulins precursor (Acrogranin) (Proep... 88 8e-18
sp|P28797|GRN_CAVPO Granulins precursor (Proepithelin) (PEP... 87 2e-17
sp|P81013|GRN1_CYPCA Granulin-1 55 6e-08
sp|P81015|GRN3_CYPCA Granulin-3 54 2e-07
sp|P80930|ENA1_HORSE Antimicrobial peptide eNAP-1 54 2e-07
sp|P81014|GRN2_CYPCA Granulin-2 49 5e-06
sp|P80059|PMD1_LOCMI Pars intercerebralis major peptide D1 ... 49 5e-06
sp|P25777|ORYB_ORYSA Oryzain beta chain precursor 44 2e-04
>sp|P23785|GRN_RAT Granulins precursor [Contains: Acrogranin; Granulin-1 (Granulin G);
Granulin-2 (Granulin F); Granulin-3 (Granulin B)
(Epithelin-2); Granulin-4 (Granulin A) (Epithelin-1);
Granulin-5 (Granulin C); Granulin-6 (Granulin D);
Granulin-7 (Granulin E)]
Length = 588
Score = 90.5 bits (223), Expect = 2e-18
Identities = 45/122 (36%), Positives = 59/122 (48%), Gaps = 2/122 (1%)
Frame = +2
Query: 8 NAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVETIDSAKIETPKYTVERSTLRE 187
NA+CC D LHCCP+ T CDL+ +CI + + + P Y V
Sbjct: 234 NAICCSDHLHCCPQDTVCDLIQSKCISK----------DYTTDLMTKLPGYPVNE----- 278
Query: 188 FMIKIGDKNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHC--VTG 361
+K + +CPDG TCC + TG +GCCPF+ VCC D CC G+ C TG
Sbjct: 279 --VKCDLEVSCPDG------YTCCRLNTGAWGCCPFTKAVCCEDHIHCCPAGFQCHTETG 330
Query: 362 GC 367
C
Sbjct: 331 TC 332
Score = 77.0 bits (188), Expect = 2e-14
Identities = 39/114 (34%), Positives = 52/114 (45%)
Frame = +2
Query: 11 AVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVETIDSAKIETPKYTVERSTLREF 190
A CC D++HCCP G +CDLV+ RCI + P+++ P R+
Sbjct: 154 ASCCEDRVHCCPHGASCDLVHTRCISPTGTH---PLLKKF-------PAQRTNRAVASFS 203
Query: 191 MIKIGDKNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHC 352
++ K CPD TCC + TG YGCCP +CC D CC C
Sbjct: 204 VVCPDAKTQCPDDS------TCCELPTGKYGCCPMPNAICCSDHLHCCPQDTVC 251
Score = 76.3 bits (186), Expect = 3e-14
Identities = 41/119 (34%), Positives = 54/119 (45%)
Frame = +2
Query: 8 NAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVETIDSAKIETPKYTVERSTLRE 187
+AVCC D+ HCCP G TC++ + C E +V+ S
Sbjct: 468 HAVCCEDRQHCCPAGYTCNVKARTC---------------------EKDAGSVQPSMDLT 506
Query: 188 FMIKIGDKNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHCVTGG 364
F K+G+ C G C Q+CC G + CCP+ GVCC D R CC G+HC G
Sbjct: 507 FGSKVGNVE-CGAGHFCHDNQSCCKDSQGGWACCPYVKGVCCRDGRHCCPIGFHCSAKG 564
Score = 72.0 bits (175), Expect = 6e-13
Identities = 35/121 (28%), Positives = 55/121 (45%)
Frame = +2
Query: 2 YSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVETIDSAKIETPKYTVERSTL 181
++ AVCC D +HCCP G C C ++ P ++ + +A + P + ++ +
Sbjct: 306 FTKAVCCEDHIHCCPAGFQCHTETGTC---ELGVLQVPWMKKV-TASLSLPDPQILKNDV 361
Query: 182 REFMIKIGDKNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHCVTG 361
C D C TCC + +G +GCCP VCC D + CC G+ C+
Sbjct: 362 P-----------CDDFSSCPSNNTCCRLSSGDWGCCPMPEAVCCLDHQHCCPQGFKCMDE 410
Query: 362 G 364
G
Sbjct: 411 G 411
Score = 61.2 bits (147), Expect = 1e-09
Identities = 34/117 (29%), Positives = 42/117 (35%)
Frame = +2
Query: 2 YSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVETIDSAKIETPKYTVERSTL 181
+S V C D HCCP G C K C S+ + ++ P
Sbjct: 86 FSEGVSCDDGQHCCPRGFHCSADGKSCSQISDSLL----------GAVQCP--------- 126
Query: 182 REFMIKIGDKNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHC 352
G + CPD TCC+M G +GCCP CC D CC G C
Sbjct: 127 -------GSQFECPDSA------TCCIMIDGSWGCCPMPQASCCEDRVHCCPHGASC 170
Score = 60.5 bits (145), Expect = 2e-09
Identities = 36/114 (31%), Positives = 46/114 (40%)
Frame = +2
Query: 11 AVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVETIDSAKIETPKYTVERSTLREF 190
AVCC D HCCP+G C ++ + D K V ++TL
Sbjct: 391 AVCCLDHQHCCPQGFKC--------------MDEGYCQKGDRMVAGLEKMPVRQTTL--- 433
Query: 191 MIKIGDKNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHC 352
++ GD C C QTCC G + CC VCC D + CC GY C
Sbjct: 434 -LQHGDIG-CDQHTSCPVGQTCCPSLKGSWACCQLPHAVCCEDRQHCCPAGYTC 485
Score = 51.6 bits (122), Expect = 8e-07
Identities = 22/52 (42%), Positives = 29/52 (55%)
Frame = +2
Query: 209 KNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHCVTGG 364
+++CPDG +C L +G CCPFS GV C D + CC G+HC G
Sbjct: 64 RDHCPDG------YSCLLTVSGTSSCCPFSEGVSCDDGQHCCPRGFHCSADG 109
Score = 34.7 bits (78), Expect = 0.10
Identities = 12/30 (40%), Positives = 15/30 (50%)
Frame = +2
Query: 2 YSNAVCCGDQLHCCPEGTTCDLVNKRCIHQ 91
Y VCC D HCCP G C +C+ +
Sbjct: 541 YVKGVCCRDGRHCCPIGFHCSAKGTKCLRK 570
>sp|P28799|GRN_HUMAN Granulins precursor (Proepithelin) (PEPI) [Contains: Acrogranin;
Paragranulin; Granulin-1 (Granulin G); Granulin-2
(Granulin F); Granulin-3 (Granulin B); Granulin-4
(Granulin A); Granulin-5 (Granulin C); Granulin-6
(Granulin D); Granulin-7 (Granulin E)]
Length = 593
Score = 88.6 bits (218), Expect = 6e-18
Identities = 42/117 (35%), Positives = 58/117 (49%)
Frame = +2
Query: 8 NAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVETIDSAKIETPKYTVERSTLRE 187
NA CC D LHCCP+ T CDL+ +C+ + N + + P +TV
Sbjct: 236 NATCCSDHLHCCPQDTVCDLIQSKCLSKENATTD---------LLTKLPAHTVGD----- 281
Query: 188 FMIKIGDKNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHCVT 358
+K + +CPDG TCC + +G +GCCPF+ VCC D CC G+ C T
Sbjct: 282 --VKCDMEVSCPDG------YTCCRLQSGAWGCCPFTQAVCCEDHIHCCPAGFTCDT 330
Score = 80.1 bits (196), Expect = 2e-15
Identities = 41/127 (32%), Positives = 54/127 (42%)
Frame = +2
Query: 2 YSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVETIDSAKIETPKYTVERSTL 181
++ AVCC D +HCCP G TCD C P + P +E + ++R
Sbjct: 309 FTQAVCCEDHIHCCPAGFTCDTQKGTC---EQGPHQVPWMEKAPAHLSLPDPQALKRDV- 364
Query: 182 REFMIKIGDKNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHCVTG 361
C + C TCC + +G +GCCP VCC D + CC GY CV
Sbjct: 365 -----------PCDNVSSCPSSDTCCQLTSGEWGCCPIPEAVCCSDHQHCCPQGYTCVAE 413
Query: 362 GCA*LGS 382
G GS
Sbjct: 414 GQCQRGS 420
Score = 75.1 bits (183), Expect = 7e-14
Identities = 41/115 (35%), Positives = 52/115 (45%), Gaps = 1/115 (0%)
Frame = +2
Query: 11 AVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVETIDSAKIETPKYTVERSTLREF 190
A CC D++HCCP G CDLV+ RCI + T AK + P R+
Sbjct: 155 ASCCEDRVHCCPHGAFCDLVHTRCITPTG---------THPLAK-KLPAQRTNRAVALSS 204
Query: 191 MIKIGD-KNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHC 352
+ D ++ CPDG TCC + +G YGCCP CC D CC C
Sbjct: 205 SVMCPDARSRCPDG------STCCELPSGKYGCCPMPNATCCSDHLHCCPQDTVC 253
Score = 73.9 bits (180), Expect = 2e-13
Identities = 38/120 (31%), Positives = 52/120 (43%), Gaps = 1/120 (0%)
Frame = +2
Query: 8 NAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVETIDSAKIETPKYTVERSTLRE 187
+AVCC D+ HCCP G TC++ + C E + + +T
Sbjct: 471 HAVCCEDRQHCCPAGYTCNVKARSC---------------------EKEVVSAQPATFLA 509
Query: 188 FMIKIGDKN-NCPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHCVTGG 364
+G K+ C +G C QTCC + CCP+ GVCC D R CC G+ C G
Sbjct: 510 RSPHVGVKDVECGEGHFCHDNQTCCRDNRQGWACCPYRQGVCCADRRHCCPAGFRCAARG 569
Score = 63.2 bits (152), Expect = 3e-10
Identities = 33/118 (27%), Positives = 40/118 (33%), Gaps = 1/118 (0%)
Frame = +2
Query: 2 YSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVETIDSAKIETPKYTVERSTL 181
+ AV CGD HCCP G C + C +S +
Sbjct: 86 FPEAVACGDGHHCCPRGFHCSADGRSCFQRSGNNSVGAI--------------------- 124
Query: 182 REFMIKIGDKNNCPDGG-QCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHC 352
CPD +C TCC+M G +GCCP CC D CC G C
Sbjct: 125 -----------QCPDSQFECPDFSTCCVMVDGSWGCCPMPQASCCEDRVHCCPHGAFC 171
Score = 63.2 bits (152), Expect = 3e-10
Identities = 38/114 (33%), Positives = 47/114 (41%)
Frame = +2
Query: 11 AVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVETIDSAKIETPKYTVERSTLREF 190
AVCC D HCCP+G TC + +C S I + + P S R+
Sbjct: 394 AVCCSDHQHCCPQGYTC-VAEGQCQRGSE----------IVAGLEKMPARRASLSHPRD- 441
Query: 191 MIKIGDKNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHC 352
I +CP G QTCC G + CC VCC D + CC GY C
Sbjct: 442 -IGCDQHTSCPVG------QTCCPSLGGSWACCQLPHAVCCEDRQHCCPAGYTC 488
Score = 43.9 bits (102), Expect = 2e-04
Identities = 17/49 (34%), Positives = 21/49 (42%)
Frame = +2
Query: 218 CPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHCVTGG 364
C C+ +C +G CCPF V C D CC G+HC G
Sbjct: 61 CQVDAHCSAGHSCIFTVSGTSSCCPFPEAVACGDGHHCCPRGFHCSADG 109
Score = 37.0 bits (84), Expect = 0.021
Identities = 12/30 (40%), Positives = 16/30 (53%)
Frame = +2
Query: 2 YSNAVCCGDQLHCCPEGTTCDLVNKRCIHQ 91
Y VCC D+ HCCP G C +C+ +
Sbjct: 546 YRQGVCCADRRHCCPAGFRCAARGTKCLRR 575
>sp|P28798|GRN_MOUSE Granulins precursor (Acrogranin) (Proepithelin) (PEPI) (PC
cell-derived growth factor) (PCDGF) [Contains: Granulin
1; Granulin 2; Granulin 3; Granulin 4; Granulin 5;
Granulin 6; Granulin 7]
Length = 589
Score = 88.2 bits (217), Expect = 8e-18
Identities = 43/117 (36%), Positives = 60/117 (51%)
Frame = +2
Query: 8 NAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVETIDSAKIETPKYTVERSTLRE 187
NA+CC D LHCCP+ T CDL+ +C+ ++ T D + P Y V+
Sbjct: 235 NAICCSDHLHCCPQDTVCDLIQSKCLSKNY---------TTDLLT-KLPGYPVKE----- 279
Query: 188 FMIKIGDKNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHCVT 358
+K + +CP+G TCC + TG +GCCPF+ VCC D CC G+ C T
Sbjct: 280 --VKCDMEVSCPEG------YTCCRLNTGAWGCCPFAKAVCCEDHIHCCPAGFQCHT 328
Score = 79.7 bits (195), Expect = 3e-15
Identities = 42/119 (35%), Positives = 58/119 (48%)
Frame = +2
Query: 8 NAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVETIDSAKIETPKYTVERSTLRE 187
+AVCC D+ HCCP G TC++ + C + + I+ PV+ T+
Sbjct: 469 HAVCCEDRQHCCPAGYTCNVKARTC-EKDVDFIQPPVLLTLGP----------------- 510
Query: 188 FMIKIGDKNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHCVTGG 364
K+G+ C +G C QTCC G + CCP+ GVCC D R CC G+HC G
Sbjct: 511 ---KVGNVE-CGEGHFCHDNQTCCKDSAGVWACCPYLKGVCCRDGRHCCPGGFHCSARG 565
Score = 77.0 bits (188), Expect = 2e-14
Identities = 39/115 (33%), Positives = 51/115 (44%), Gaps = 1/115 (0%)
Frame = +2
Query: 11 AVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVETIDSAKIETPKYTVERSTLREF 190
A CC D++HCCP G +CDLV+ RC+ + + + P R+ F
Sbjct: 154 ASCCEDRVHCCPHGASCDLVHTRCVSPTGT----------HTLLKKFPAQKTNRAVSLPF 203
Query: 191 MIKIGD-KNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHC 352
+ D K CPD TCC + TG YGCCP +CC D CC C
Sbjct: 204 SVVCPDAKTQCPDDS------TCCELPTGKYGCCPMPNAICCSDHLHCCPQDTVC 252
Score = 74.3 bits (181), Expect = 1e-13
Identities = 36/121 (29%), Positives = 52/121 (42%)
Frame = +2
Query: 2 YSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVETIDSAKIETPKYTVERSTL 181
++ AVCC D +HCCP G C H E +++ K+ P + L
Sbjct: 307 FAKAVCCEDHIHCCPAGFQC--------HTEKGTCEMGILQVPWMKKVIAPLRLPDPQIL 358
Query: 182 REFMIKIGDKNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHCVTG 361
+ C D +C TCC + +G +GCCP VCC D + CC G+ C+
Sbjct: 359 KS-------DTPCDDFTRCPTNNTCCKLNSGDWGCCPIPEAVCCSDNQHCCPQGFTCLAQ 411
Query: 362 G 364
G
Sbjct: 412 G 412
Score = 70.9 bits (172), Expect = 1e-12
Identities = 36/117 (30%), Positives = 45/117 (38%)
Frame = +2
Query: 2 YSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVETIDSAKIETPKYTVERSTL 181
+S V CGD HCCP+G C K C S+ P+ ++ P
Sbjct: 86 FSKGVSCGDGYHCCPQGFHCSADGKSCFQMSDNPL----------GAVQCP--------- 126
Query: 182 REFMIKIGDKNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHC 352
G + CPD TCC+M G +GCCP CC D CC G C
Sbjct: 127 -------GSQFECPDSA------TCCIMVDGSWGCCPMPQASCCEDRVHCCPHGASC 170
Score = 65.1 bits (157), Expect = 7e-11
Identities = 39/115 (33%), Positives = 48/115 (41%), Gaps = 1/115 (0%)
Frame = +2
Query: 11 AVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVETIDSAKIETPKYTVERSTLREF 190
AVCC D HCCP+G TC L C K +T +E+ R+
Sbjct: 392 AVCCSDNQHCCPQGFTC-LAQGYC------------------QKGDTMVAGLEKIPARQT 432
Query: 191 M-IKIGDKNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHC 352
++IGD C C QTCC G + CC VCC D + CC GY C
Sbjct: 433 TPLQIGDIG-CDQHTSCPVGQTCCPSLKGSWACCQLPHAVCCEDRQHCCPAGYTC 486
Score = 51.2 bits (121), Expect = 1e-06
Identities = 21/50 (42%), Positives = 25/50 (50%)
Frame = +2
Query: 215 NCPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHCVTGG 364
+C G C +C L +G CCPFS GV C D CC G+HC G
Sbjct: 60 SCQTHGHCPAGYSCLLTVSGTSSCCPFSKGVSCGDGYHCCPQGFHCSADG 109
Score = 34.7 bits (78), Expect = 0.10
Identities = 12/30 (40%), Positives = 15/30 (50%)
Frame = +2
Query: 2 YSNAVCCGDQLHCCPEGTTCDLVNKRCIHQ 91
Y VCC D HCCP G C +C+ +
Sbjct: 542 YLKGVCCRDGRHCCPGGFHCSARGTKCLRK 571
>sp|P28797|GRN_CAVPO Granulins precursor (Proepithelin) (PEPI) [Contains: Acrogranin;
Granulin-1; Granulin-2; Granulin-3; Granulin-4;
Granulin-5; Granulin-6; Granulin-7]
Length = 591
Score = 86.7 bits (213), Expect = 2e-17
Identities = 41/117 (35%), Positives = 58/117 (49%)
Frame = +2
Query: 8 NAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVETIDSAKIETPKYTVERSTLRE 187
NA+CC D LHCCP+ T CDL RC+ Q+ + + P +TV
Sbjct: 236 NAICCSDHLHCCPQDTVCDLRQSRCLSQNKAK----------TLLTKLPSWTV------- 278
Query: 188 FMIKIGDKNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHCVT 358
+ ++ + +CP+G QTCC + +G +GCCPF VCC D CC + C T
Sbjct: 279 WDVECDQEVSCPEG------QTCCRLQSGKWGCCPFPKAVCCEDHVHCCPERFRCHT 329
Score = 80.5 bits (197), Expect = 2e-15
Identities = 43/119 (36%), Positives = 55/119 (46%)
Frame = +2
Query: 8 NAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVETIDSAKIETPKYTVERSTLRE 187
+AVCC D HCCP G TC++ + C + D A + P ST
Sbjct: 468 HAVCCEDGQHCCPAGYTCNVKARSC------------EKAADGAHLAAP--LAVGSTGGV 513
Query: 188 FMIKIGDKNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHCVTGG 364
+ GD++ C D QTCC G + CCPF GVCC D R CC G+HC + G
Sbjct: 514 MDVACGDRHFCHDE------QTCCRDSRGGWACCPFHQGVCCKDQRHCCPAGFHCESQG 566
Score = 76.6 bits (187), Expect = 2e-14
Identities = 43/120 (35%), Positives = 59/120 (49%), Gaps = 6/120 (5%)
Frame = +2
Query: 11 AVCCGDQLHCCPEGTTCDLVNKRCIHQ-SNEPI--EWPVVETIDSAKIETPKYT--VERS 175
A CC D++HCCP G +CDLV+ RC+ + P+ + P T + TP + + +
Sbjct: 141 ASCCEDRVHCCPHGASCDLVHIRCVTALGSHPLTTKLPAQRTNYTGAEGTPVVSPGLLPA 200
Query: 176 TLREFMIKIGDKNNCPDG-GQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHC 352
L +I CPD QC TCCL+ +G YGCCP +CC D CC C
Sbjct: 201 ALPTSVI-------CPDSRSQCPDDTTCCLLASGEYGCCPMPNAICCSDHLHCCPQDTVC 253
Score = 60.5 bits (145), Expect = 2e-09
Identities = 34/118 (28%), Positives = 43/118 (36%), Gaps = 1/118 (0%)
Frame = +2
Query: 2 YSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVETIDSAKIETPKYTVERSTL 181
+S A+ CGD HCCP G C CI + P + + + +
Sbjct: 72 FSQAMACGDGHHCCPYGFHCSTDGGTCIQR-------PDIHLLGAVQ------------- 111
Query: 182 REFMIKIGDKNNCPDGG-QCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHC 352
CP G +C TCC M G +GCCP CC D CC G C
Sbjct: 112 ------------CPGGEFECPDSSTCCHMLDGSWGCCPMPQASCCEDRVHCCPHGASC 157
Score = 47.4 bits (111), Expect = 2e-05
Identities = 27/104 (25%), Positives = 39/104 (37%)
Frame = +2
Query: 2 YSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVETIDSAKIETPKYTVERSTL 181
+ AVCC D +HCCPE C C Q + W ++ P
Sbjct: 308 FPKAVCCEDHVHCCPERFRCHTEKDTC-EQGLLQVPWAQKTPAQPSRPSQPSPPGPPGPP 366
Query: 182 REFMIKIGDKNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCC 313
+ + +C + C CC + +G +GCCP S G C
Sbjct: 367 SP-PGPLRSEISCDEVVSCRPGNICCRLASGEWGCCPSSEGYLC 409
Score = 46.6 bits (109), Expect = 3e-05
Identities = 21/50 (42%), Positives = 24/50 (48%)
Frame = +2
Query: 215 NCPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHCVTGG 364
NCP G +C L G CCPFS + C D CC G+HC T G
Sbjct: 52 NCPIG------HSCVLTAAGTAACCPFSQAMACGDGHHCCPYGFHCSTDG 95
Score = 46.2 bits (108), Expect = 3e-05
Identities = 32/118 (27%), Positives = 46/118 (38%), Gaps = 5/118 (4%)
Frame = +2
Query: 14 VCC---GDQLHCCP--EGTTCDLVNKRCIHQSNEPIEWPVVETIDSAKIETPKYTVERST 178
+CC + CCP EG C + +RC V + + K+ ++ ++T
Sbjct: 389 ICCRLASGEWGCCPSSEGYLC-MAGERC----------QVGDRLAPEKMAAHLMSLSQTT 437
Query: 179 LREFMIKIGDKNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHC 352
+G C C QTCC G + CC VCC D + CC GY C
Sbjct: 438 ------DVG----CDQHASCPVRQTCCPKLGGGWACCQLPHAVCCEDGQHCCPAGYTC 485
Score = 42.4 bits (98), Expect = 5e-04
Identities = 14/32 (43%), Positives = 19/32 (59%)
Frame = +2
Query: 2 YSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSN 97
+ VCC DQ HCCP G C+ RC+H+ +
Sbjct: 543 FHQGVCCKDQRHCCPAGFHCESQGTRCVHKKS 574
>sp|P81013|GRN1_CYPCA Granulin-1
Length = 57
Score = 55.5 bits (132), Expect = 6e-08
Identities = 24/45 (53%), Positives = 26/45 (57%)
Frame = +2
Query: 218 CPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHC 352
CPDG TCCL G + CCPFS+G CC D CC GYHC
Sbjct: 10 CPDG------TTCCLSPYGVWYCCPFSMGQCCRDGIHCCRHGYHC 48
Score = 33.5 bits (75), Expect = 0.23
Identities = 11/28 (39%), Positives = 15/28 (53%)
Frame = +2
Query: 2 YSNAVCCGDQLHCCPEGTTCDLVNKRCI 85
+S CC D +HCC G CD + C+
Sbjct: 29 FSMGQCCRDGIHCCRHGYHCDSTSTHCL 56
>sp|P81015|GRN3_CYPCA Granulin-3
Length = 57
Score = 53.9 bits (128), Expect = 2e-07
Identities = 22/45 (48%), Positives = 24/45 (53%)
Frame = +2
Query: 218 CPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHC 352
C G C TCC G + CCPF +G CC D R CC GYHC
Sbjct: 4 CDAGITCPSGTTCCRSPFGVWYCCPFLMGQCCRDGRHCCRHGYHC 48
Score = 30.0 bits (66), Expect = 2.6
Identities = 10/23 (43%), Positives = 12/23 (52%)
Frame = +2
Query: 17 CCGDQLHCCPEGTTCDLVNKRCI 85
CC D HCC G CD + C+
Sbjct: 34 CCRDGRHCCRHGYHCDSTSTLCL 56
>sp|P80930|ENA1_HORSE Antimicrobial peptide eNAP-1
Length = 46
Score = 53.9 bits (128), Expect = 2e-07
Identities = 21/43 (48%), Positives = 24/43 (55%)
Frame = +2
Query: 218 CPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGY 346
C +G C QTCC G CCP+S GVCC D R CC G+
Sbjct: 4 CGEGHFCHDXQTCCRASQGGXACCPYSQGVCCADQRHCCPVGF 46
Score = 35.0 bits (79), Expect = 0.080
Identities = 12/17 (70%), Positives = 12/17 (70%)
Frame = +2
Query: 2 YSNAVCCGDQLHCCPEG 52
YS VCC DQ HCCP G
Sbjct: 29 YSQGVCCADQRHCCPVG 45
>sp|P81014|GRN2_CYPCA Granulin-2
Length = 57
Score = 48.9 bits (115), Expect = 5e-06
Identities = 19/39 (48%), Positives = 21/39 (53%)
Frame = +2
Query: 236 CAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHC 352
C TCC G + CCPF +G CC D R CC GY C
Sbjct: 10 CPSRTTCCRSPFGVWYCCPFLMGQCCRDGRHCCRHGYRC 48
Score = 30.4 bits (67), Expect = 2.0
Identities = 10/23 (43%), Positives = 12/23 (52%)
Frame = +2
Query: 17 CCGDQLHCCPEGTTCDLVNKRCI 85
CC D HCC G CD + C+
Sbjct: 34 CCRDGRHCCRHGYRCDSTSTLCL 56
>sp|P80059|PMD1_LOCMI Pars intercerebralis major peptide D1 (PMP-D1)
Length = 54
Score = 48.9 bits (115), Expect = 5e-06
Identities = 19/39 (48%), Positives = 21/39 (53%)
Frame = +2
Query: 236 CAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHC 352
C G +TCC G GCCP+ GVCC D CC G C
Sbjct: 7 CPGTETCCTTPQGEEGCCPYKEGVCCLDGIHCCPSGTVC 45
Score = 45.1 bits (105), Expect = 8e-05
Identities = 16/28 (57%), Positives = 19/28 (67%)
Frame = +2
Query: 2 YSNAVCCGDQLHCCPEGTTCDLVNKRCI 85
Y VCC D +HCCP GT CD ++RCI
Sbjct: 26 YKEGVCCLDGIHCCPSGTVCDEDHRRCI 53
>sp|P25777|ORYB_ORYSA Oryzain beta chain precursor
Length = 471
Score = 43.5 bits (101), Expect = 2e-04
Identities = 19/50 (38%), Positives = 24/50 (48%), Gaps = 3/50 (6%)
Frame = +2
Query: 206 DKNNCPDGGQCA---GLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGY 346
D +CP G C G + CL++ GCCP CC D +CC P Y
Sbjct: 387 DNFSCPAGSTCCCAFGFRNLCLVW----GCCPVEGATCCKDHASCCPPDY 432
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 56,294,474
Number of Sequences: 369166
Number of extensions: 1221135
Number of successful extensions: 4106
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3707
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4035
length of database: 68,354,980
effective HSP length: 101
effective length of database: 49,696,745
effective search space used: 2534533995
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)