Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_002_G06
(476 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P23785|GRN_RAT Granulins precursor [Contains: Acrogranin... 98 1e-20
sp|P28799|GRN_HUMAN Granulins precursor (Proepithelin) (PEP... 96 4e-20
sp|P28798|GRN_MOUSE Granulins precursor (Acrogranin) (Proep... 96 6e-20
sp|P28797|GRN_CAVPO Granulins precursor (Proepithelin) (PEP... 94 2e-19
sp|P81013|GRN1_CYPCA Granulin-1 55 6e-08
sp|P81015|GRN3_CYPCA Granulin-3 54 2e-07
sp|P80930|ENA1_HORSE Antimicrobial peptide eNAP-1 54 2e-07
sp|P80059|PMD1_LOCMI Pars intercerebralis major peptide D1 ... 52 5e-07
sp|P81014|GRN2_CYPCA Granulin-2 49 6e-06
sp|P25777|ORYB_ORYSA Oryzain beta chain precursor 44 3e-04
>sp|P23785|GRN_RAT Granulins precursor [Contains: Acrogranin; Granulin-1 (Granulin G);
Granulin-2 (Granulin F); Granulin-3 (Granulin B)
(Epithelin-2); Granulin-4 (Granulin A) (Epithelin-1);
Granulin-5 (Granulin C); Granulin-6 (Granulin D);
Granulin-7 (Granulin E)]
Length = 588
Score = 97.8 bits (242), Expect = 1e-20
Identities = 48/131 (36%), Positives = 63/131 (48%), Gaps = 2/131 (1%)
Frame = +2
Query: 2 GGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVETIDSAKIETPKY 181
G + CC NA+CC D LHCCP+ T CDL+ +CI + + + P Y
Sbjct: 225 GKYGCCPMPNAICCSDHLHCCPQDTVCDLIQSKCISK----------DYTTDLMTKLPGY 274
Query: 182 TVERSTLREFMIKIGDKNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAP 361
V +K + +CPDG TCC + TG +GCCPF+ VCC D CC
Sbjct: 275 PVNE-------VKCDLEVSCPDG------YTCCRLNTGAWGCCPFTKAVCCEDHIHCCPA 321
Query: 362 GYHC--VTGGC 388
G+ C TG C
Sbjct: 322 GFQCHTETGTC 332
Score = 85.5 bits (210), Expect = 6e-17
Identities = 45/128 (35%), Positives = 58/128 (45%)
Frame = +2
Query: 2 GGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVETIDSAKIETPKY 181
G CCQ +AVCC D+ HCCP G TC++ + C E
Sbjct: 459 GSWACCQLPHAVCCEDRQHCCPAGYTCNVKARTC---------------------EKDAG 497
Query: 182 TVERSTLREFMIKIGDKNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAP 361
+V+ S F K+G+ C G C Q+CC G + CCP+ GVCC D R CC
Sbjct: 498 SVQPSMDLTFGSKVGNVE-CGAGHFCHDNQSCCKDSQGGWACCPYVKGVCCRDGRHCCPI 556
Query: 362 GYHCVTGG 385
G+HC G
Sbjct: 557 GFHCSAKG 564
Score = 83.6 bits (205), Expect = 2e-16
Identities = 42/124 (33%), Positives = 56/124 (45%)
Frame = +2
Query: 2 GGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVETIDSAKIETPKY 181
G CC A CC D++HCCP G +CDLV+ RCI + P+++ + P
Sbjct: 144 GSWGCCPMPQASCCEDRVHCCPHGASCDLVHTRCISPTG---THPLLK-------KFPAQ 193
Query: 182 TVERSTLREFMIKIGDKNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAP 361
R+ ++ K CPD TCC + TG YGCCP +CC D CC
Sbjct: 194 RTNRAVASFSVVCPDAKTQCPDD------STCCELPTGKYGCCPMPNAICCSDHLHCCPQ 247
Query: 362 GYHC 373
C
Sbjct: 248 DTVC 251
Score = 79.3 bits (194), Expect = 4e-15
Identities = 38/128 (29%), Positives = 58/128 (45%)
Frame = +2
Query: 2 GGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVETIDSAKIETPKY 181
G CC ++ AVCC D +HCCP G C C ++ P ++ + +A + P
Sbjct: 299 GAWGCCPFTKAVCCEDHIHCCPAGFQCHTETGTC---ELGVLQVPWMKKV-TASLSLPDP 354
Query: 182 TVERSTLREFMIKIGDKNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAP 361
+ ++ + C D C TCC + +G +GCCP VCC D + CC
Sbjct: 355 QILKNDVP-----------CDDFSSCPSNNTCCRLSSGDWGCCPMPEAVCCLDHQHCCPQ 403
Query: 362 GYHCVTGG 385
G+ C+ G
Sbjct: 404 GFKCMDEG 411
Score = 68.9 bits (167), Expect = 6e-12
Identities = 37/124 (29%), Positives = 45/124 (36%)
Frame = +2
Query: 2 GGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVETIDSAKIETPKY 181
G CC +S V C D HCCP G C K C S+ + ++ P
Sbjct: 79 GTSSCCPFSEGVSCDDGQHCCPRGFHCSADGKSCSQISDSLL----------GAVQCP-- 126
Query: 182 TVERSTLREFMIKIGDKNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAP 361
G + CPD TCC+M G +GCCP CC D CC
Sbjct: 127 --------------GSQFECPDSA------TCCIMIDGSWGCCPMPQASCCEDRVHCCPH 166
Query: 362 GYHC 373
G C
Sbjct: 167 GASC 170
Score = 66.6 bits (161), Expect = 3e-11
Identities = 39/124 (31%), Positives = 49/124 (39%)
Frame = +2
Query: 2 GGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVETIDSAKIETPKY 181
G CC AVCC D HCCP+G C ++ + D K
Sbjct: 381 GDWGCCPMPEAVCCLDHQHCCPQGFKC--------------MDEGYCQKGDRMVAGLEKM 426
Query: 182 TVERSTLREFMIKIGDKNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAP 361
V ++TL ++ GD C C QTCC G + CC VCC D + CC
Sbjct: 427 PVRQTTL----LQHGDIG-CDQHTSCPVGQTCCPSLKGSWACCQLPHAVCCEDRQHCCPA 481
Query: 362 GYHC 373
GY C
Sbjct: 482 GYTC 485
Score = 51.6 bits (122), Expect = 9e-07
Identities = 22/52 (42%), Positives = 29/52 (55%)
Frame = +2
Query: 230 KNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHCVTGG 385
+++CPDG +C L +G CCPFS GV C D + CC G+HC G
Sbjct: 64 RDHCPDG------YSCLLTVSGTSSCCPFSEGVSCDDGQHCCPRGFHCSADG 109
Score = 44.7 bits (104), Expect = 1e-04
Identities = 16/37 (43%), Positives = 19/37 (51%)
Frame = +2
Query: 2 GGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQ 112
GG CC Y VCC D HCCP G C +C+ +
Sbjct: 534 GGWACCPYVKGVCCRDGRHCCPIGFHCSAKGTKCLRK 570
>sp|P28799|GRN_HUMAN Granulins precursor (Proepithelin) (PEPI) [Contains: Acrogranin;
Paragranulin; Granulin-1 (Granulin G); Granulin-2
(Granulin F); Granulin-3 (Granulin B); Granulin-4
(Granulin A); Granulin-5 (Granulin C); Granulin-6
(Granulin D); Granulin-7 (Granulin E)]
Length = 593
Score = 95.9 bits (237), Expect = 4e-20
Identities = 45/126 (35%), Positives = 62/126 (49%)
Frame = +2
Query: 2 GGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVETIDSAKIETPKY 181
G + CC NA CC D LHCCP+ T CDL+ +C+ + N + + P +
Sbjct: 227 GKYGCCPMPNATCCSDHLHCCPQDTVCDLIQSKCLSKENATTD---------LLTKLPAH 277
Query: 182 TVERSTLREFMIKIGDKNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAP 361
TV +K + +CPDG TCC + +G +GCCPF+ VCC D CC
Sbjct: 278 TVGD-------VKCDMEVSCPDG------YTCCRLQSGAWGCCPFTQAVCCEDHIHCCPA 324
Query: 362 GYHCVT 379
G+ C T
Sbjct: 325 GFTCDT 330
Score = 87.4 bits (215), Expect = 2e-17
Identities = 44/134 (32%), Positives = 57/134 (42%)
Frame = +2
Query: 2 GGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVETIDSAKIETPKY 181
G CC ++ AVCC D +HCCP G TCD C P + P +E +
Sbjct: 302 GAWGCCPFTQAVCCEDHIHCCPAGFTCDTQKGTC---EQGPHQVPWMEKAPAHLSLPDPQ 358
Query: 182 TVERSTLREFMIKIGDKNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAP 361
++R C + C TCC + +G +GCCP VCC D + CC
Sbjct: 359 ALKRDV------------PCDNVSSCPSSDTCCQLTSGEWGCCPIPEAVCCSDHQHCCPQ 406
Query: 362 GYHCVTGGCA*LGS 403
GY CV G GS
Sbjct: 407 GYTCVAEGQCQRGS 420
Score = 83.2 bits (204), Expect = 3e-16
Identities = 42/129 (32%), Positives = 56/129 (43%), Gaps = 1/129 (0%)
Frame = +2
Query: 2 GGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVETIDSAKIETPKY 181
G CCQ +AVCC D+ HCCP G TC++ + C E
Sbjct: 462 GSWACCQLPHAVCCEDRQHCCPAGYTCNVKARSC---------------------EKEVV 500
Query: 182 TVERSTLREFMIKIGDKN-NCPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCA 358
+ + +T +G K+ C +G C QTCC + CCP+ GVCC D R CC
Sbjct: 501 SAQPATFLARSPHVGVKDVECGEGHFCHDNQTCCRDNRQGWACCPYRQGVCCADRRHCCP 560
Query: 359 PGYHCVTGG 385
G+ C G
Sbjct: 561 AGFRCAARG 569
Score = 81.6 bits (200), Expect = 8e-16
Identities = 44/125 (35%), Positives = 55/125 (44%), Gaps = 1/125 (0%)
Frame = +2
Query: 2 GGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVETIDSAKIETPKY 181
G CC A CC D++HCCP G CDLV+ RCI + T AK + P
Sbjct: 145 GSWGCCPMPQASCCEDRVHCCPHGAFCDLVHTRCITPTG---------THPLAK-KLPAQ 194
Query: 182 TVERSTLREFMIKIGD-KNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCA 358
R+ + D ++ CPDG TCC + +G YGCCP CC D CC
Sbjct: 195 RTNRAVALSSSVMCPDARSRCPDG------STCCELPSGKYGCCPMPNATCCSDHLHCCP 248
Query: 359 PGYHC 373
C
Sbjct: 249 QDTVC 253
Score = 70.9 bits (172), Expect = 1e-12
Identities = 36/125 (28%), Positives = 43/125 (34%), Gaps = 1/125 (0%)
Frame = +2
Query: 2 GGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVETIDSAKIETPKY 181
G CC + AV CGD HCCP G C + C +S +
Sbjct: 79 GTSSCCPFPEAVACGDGHHCCPRGFHCSADGRSCFQRSGNNSVGAI-------------- 124
Query: 182 TVERSTLREFMIKIGDKNNCPDGG-QCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCA 358
CPD +C TCC+M G +GCCP CC D CC
Sbjct: 125 ------------------QCPDSQFECPDFSTCCVMVDGSWGCCPMPQASCCEDRVHCCP 166
Query: 359 PGYHC 373
G C
Sbjct: 167 HGAFC 171
Score = 68.9 bits (167), Expect = 6e-12
Identities = 40/120 (33%), Positives = 49/120 (40%)
Frame = +2
Query: 14 CCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVETIDSAKIETPKYTVER 193
CC AVCC D HCCP+G TC + +C S I + + P
Sbjct: 388 CCPIPEAVCCSDHQHCCPQGYTC-VAEGQCQRGSE----------IVAGLEKMPARRASL 436
Query: 194 STLREFMIKIGDKNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHC 373
S R+ I +CP G QTCC G + CC VCC D + CC GY C
Sbjct: 437 SHPRD--IGCDQHTSCPVG------QTCCPSLGGSWACCQLPHAVCCEDRQHCCPAGYTC 488
Score = 44.7 bits (104), Expect = 1e-04
Identities = 15/36 (41%), Positives = 19/36 (52%)
Frame = +2
Query: 5 GHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQ 112
G CC Y VCC D+ HCCP G C +C+ +
Sbjct: 540 GWACCPYRQGVCCADRRHCCPAGFRCAARGTKCLRR 575
Score = 43.9 bits (102), Expect = 2e-04
Identities = 17/49 (34%), Positives = 21/49 (42%)
Frame = +2
Query: 239 CPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHCVTGG 385
C C+ +C +G CCPF V C D CC G+HC G
Sbjct: 61 CQVDAHCSAGHSCIFTVSGTSSCCPFPEAVACGDGHHCCPRGFHCSADG 109
>sp|P28798|GRN_MOUSE Granulins precursor (Acrogranin) (Proepithelin) (PEPI) (PC
cell-derived growth factor) (PCDGF) [Contains: Granulin
1; Granulin 2; Granulin 3; Granulin 4; Granulin 5;
Granulin 6; Granulin 7]
Length = 589
Score = 95.5 bits (236), Expect = 6e-20
Identities = 46/126 (36%), Positives = 64/126 (50%)
Frame = +2
Query: 2 GGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVETIDSAKIETPKY 181
G + CC NA+CC D LHCCP+ T CDL+ +C+ ++ T D + P Y
Sbjct: 226 GKYGCCPMPNAICCSDHLHCCPQDTVCDLIQSKCLSKN---------YTTD-LLTKLPGY 275
Query: 182 TVERSTLREFMIKIGDKNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAP 361
V+ +K + +CP+G TCC + TG +GCCPF+ VCC D CC
Sbjct: 276 PVKE-------VKCDMEVSCPEG------YTCCRLNTGAWGCCPFAKAVCCEDHIHCCPA 322
Query: 362 GYHCVT 379
G+ C T
Sbjct: 323 GFQCHT 328
Score = 89.0 bits (219), Expect = 5e-18
Identities = 46/128 (35%), Positives = 62/128 (48%)
Frame = +2
Query: 2 GGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVETIDSAKIETPKY 181
G CCQ +AVCC D+ HCCP G TC++ + C + + I+ PV+ T+
Sbjct: 460 GSWACCQLPHAVCCEDRQHCCPAGYTCNVKARTC-EKDVDFIQPPVLLTLGP-------- 510
Query: 182 TVERSTLREFMIKIGDKNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAP 361
K+G+ C +G C QTCC G + CCP+ GVCC D R CC
Sbjct: 511 ------------KVGNVE-CGEGHFCHDNQTCCKDSAGVWACCPYLKGVCCRDGRHCCPG 557
Query: 362 GYHCVTGG 385
G+HC G
Sbjct: 558 GFHCSARG 565
Score = 83.6 bits (205), Expect = 2e-16
Identities = 42/125 (33%), Positives = 54/125 (43%), Gaps = 1/125 (0%)
Frame = +2
Query: 2 GGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVETIDSAKIETPKY 181
G CC A CC D++HCCP G +CDLV+ RC+ + + + P
Sbjct: 144 GSWGCCPMPQASCCEDRVHCCPHGASCDLVHTRCVSPTG----------THTLLKKFPAQ 193
Query: 182 TVERSTLREFMIKIGD-KNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCA 358
R+ F + D K CPD TCC + TG YGCCP +CC D CC
Sbjct: 194 KTNRAVSLPFSVVCPDAKTQCPDD------STCCELPTGKYGCCPMPNAICCSDHLHCCP 247
Query: 359 PGYHC 373
C
Sbjct: 248 QDTVC 252
Score = 81.6 bits (200), Expect = 8e-16
Identities = 39/128 (30%), Positives = 55/128 (42%)
Frame = +2
Query: 2 GGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVETIDSAKIETPKY 181
G CC ++ AVCC D +HCCP G C H E +++ K+ P
Sbjct: 300 GAWGCCPFAKAVCCEDHIHCCPAGFQC--------HTEKGTCEMGILQVPWMKKVIAPLR 351
Query: 182 TVERSTLREFMIKIGDKNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAP 361
+ L+ C D +C TCC + +G +GCCP VCC D + CC
Sbjct: 352 LPDPQILKS-------DTPCDDFTRCPTNNTCCKLNSGDWGCCPIPEAVCCSDNQHCCPQ 404
Query: 362 GYHCVTGG 385
G+ C+ G
Sbjct: 405 GFTCLAQG 412
Score = 78.6 bits (192), Expect = 7e-15
Identities = 39/124 (31%), Positives = 48/124 (38%)
Frame = +2
Query: 2 GGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVETIDSAKIETPKY 181
G CC +S V CGD HCCP+G C K C S+ P+ ++ P
Sbjct: 79 GTSSCCPFSKGVSCGDGYHCCPQGFHCSADGKSCFQMSDNPL----------GAVQCP-- 126
Query: 182 TVERSTLREFMIKIGDKNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAP 361
G + CPD TCC+M G +GCCP CC D CC
Sbjct: 127 --------------GSQFECPDSA------TCCIMVDGSWGCCPMPQASCCEDRVHCCPH 166
Query: 362 GYHC 373
G C
Sbjct: 167 GASC 170
Score = 71.2 bits (173), Expect = 1e-12
Identities = 42/125 (33%), Positives = 51/125 (40%), Gaps = 1/125 (0%)
Frame = +2
Query: 2 GGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVETIDSAKIETPKY 181
G CC AVCC D HCCP+G TC L C K +T
Sbjct: 382 GDWGCCPIPEAVCCSDNQHCCPQGFTC-LAQGYC------------------QKGDTMVA 422
Query: 182 TVERSTLREFM-IKIGDKNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCA 358
+E+ R+ ++IGD C C QTCC G + CC VCC D + CC
Sbjct: 423 GLEKIPARQTTPLQIGDIG-CDQHTSCPVGQTCCPSLKGSWACCQLPHAVCCEDRQHCCP 481
Query: 359 PGYHC 373
GY C
Sbjct: 482 AGYTC 486
Score = 51.2 bits (121), Expect = 1e-06
Identities = 21/50 (42%), Positives = 25/50 (50%)
Frame = +2
Query: 236 NCPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHCVTGG 385
+C G C +C L +G CCPFS GV C D CC G+HC G
Sbjct: 60 SCQTHGHCPAGYSCLLTVSGTSSCCPFSKGVSCGDGYHCCPQGFHCSADG 109
Score = 41.2 bits (95), Expect = 0.001
Identities = 14/33 (42%), Positives = 17/33 (51%)
Frame = +2
Query: 14 CCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQ 112
CC Y VCC D HCCP G C +C+ +
Sbjct: 539 CCPYLKGVCCRDGRHCCPGGFHCSARGTKCLRK 571
>sp|P28797|GRN_CAVPO Granulins precursor (Proepithelin) (PEPI) [Contains: Acrogranin;
Granulin-1; Granulin-2; Granulin-3; Granulin-4;
Granulin-5; Granulin-6; Granulin-7]
Length = 591
Score = 94.0 bits (232), Expect = 2e-19
Identities = 44/126 (34%), Positives = 62/126 (49%)
Frame = +2
Query: 2 GGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVETIDSAKIETPKY 181
G + CC NA+CC D LHCCP+ T CDL RC+ Q+ + + P +
Sbjct: 227 GEYGCCPMPNAICCSDHLHCCPQDTVCDLRQSRCLSQNK----------AKTLLTKLPSW 276
Query: 182 TVERSTLREFMIKIGDKNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAP 361
TV + ++ + +CP+G QTCC + +G +GCCPF VCC D CC
Sbjct: 277 TV-------WDVECDQEVSCPEG------QTCCRLQSGKWGCCPFPKAVCCEDHVHCCPE 323
Query: 362 GYHCVT 379
+ C T
Sbjct: 324 RFRCHT 329
Score = 92.0 bits (227), Expect = 6e-19
Identities = 48/128 (37%), Positives = 60/128 (46%)
Frame = +2
Query: 2 GGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVETIDSAKIETPKY 181
GG CCQ +AVCC D HCCP G TC++ + C + D A + P
Sbjct: 459 GGWACCQLPHAVCCEDGQHCCPAGYTCNVKARSC------------EKAADGAHLAAP-- 504
Query: 182 TVERSTLREFMIKIGDKNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAP 361
ST + GD++ C D QTCC G + CCPF GVCC D R CC
Sbjct: 505 LAVGSTGGVMDVACGDRHFCHDE------QTCCRDSRGGWACCPFHQGVCCKDQRHCCPA 558
Query: 362 GYHCVTGG 385
G+HC + G
Sbjct: 559 GFHCESQG 566
Score = 83.2 bits (204), Expect = 3e-16
Identities = 46/130 (35%), Positives = 62/130 (47%), Gaps = 6/130 (4%)
Frame = +2
Query: 2 GGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQ-SNEPI--EWPVVETIDSAKIET 172
G CC A CC D++HCCP G +CDLV+ RC+ + P+ + P T + T
Sbjct: 131 GSWGCCPMPQASCCEDRVHCCPHGASCDLVHIRCVTALGSHPLTTKLPAQRTNYTGAEGT 190
Query: 173 PKYT--VERSTLREFMIKIGDKNNCPDG-GQCAGLQTCCLMYTGHYGCCPFSLGVCCPDL 343
P + + + L +I CPD QC TCCL+ +G YGCCP +CC D
Sbjct: 191 PVVSPGLLPAALPTSVI-------CPDSRSQCPDDTTCCLLASGEYGCCPMPNAICCSDH 243
Query: 344 RTCCAPGYHC 373
CC C
Sbjct: 244 LHCCPQDTVC 253
Score = 67.4 bits (163), Expect = 2e-11
Identities = 37/125 (29%), Positives = 46/125 (36%), Gaps = 1/125 (0%)
Frame = +2
Query: 2 GGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVETIDSAKIETPKY 181
G CC +S A+ CGD HCCP G C CI + P + + + +
Sbjct: 65 GTAACCPFSQAMACGDGHHCCPYGFHCSTDGGTCIQR-------PDIHLLGAVQ------ 111
Query: 182 TVERSTLREFMIKIGDKNNCPDGG-QCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCA 358
CP G +C TCC M G +GCCP CC D CC
Sbjct: 112 -------------------CPGGEFECPDSSTCCHMLDGSWGCCPMPQASCCEDRVHCCP 152
Query: 359 PGYHC 373
G C
Sbjct: 153 HGASC 157
Score = 53.9 bits (128), Expect = 2e-07
Identities = 29/107 (27%), Positives = 41/107 (38%)
Frame = +2
Query: 14 CCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVETIDSAKIETPKYTVER 193
CC + AVCC D +HCCPE C C Q + W ++ P
Sbjct: 305 CCPFPKAVCCEDHVHCCPERFRCHTEKDTC-EQGLLQVPWAQKTPAQPSRPSQPSPPGPP 363
Query: 194 STLREFMIKIGDKNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCC 334
+ + +C + C CC + +G +GCCP S G C
Sbjct: 364 GPPSP-PGPLRSEISCDEVVSCRPGNICCRLASGEWGCCPSSEGYLC 409
Score = 52.4 bits (124), Expect = 5e-07
Identities = 18/39 (46%), Positives = 23/39 (58%)
Frame = +2
Query: 2 GGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSN 118
GG CC + VCC DQ HCCP G C+ RC+H+ +
Sbjct: 536 GGWACCPFHQGVCCKDQRHCCPAGFHCESQGTRCVHKKS 574
Score = 47.0 bits (110), Expect = 2e-05
Identities = 33/125 (26%), Positives = 50/125 (40%), Gaps = 2/125 (1%)
Frame = +2
Query: 5 GHQCCQYSNAVCCGDQLHCCP--EGTTCDLVNKRCIHQSNEPIEWPVVETIDSAKIETPK 178
G+ CC+ ++ + CCP EG C + +RC V + + K+
Sbjct: 387 GNICCRLASG-----EWGCCPSSEGYLC-MAGERC----------QVGDRLAPEKMAAHL 430
Query: 179 YTVERSTLREFMIKIGDKNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCA 358
++ ++T +G C C QTCC G + CC VCC D + CC
Sbjct: 431 MSLSQTT------DVG----CDQHASCPVRQTCCPKLGGGWACCQLPHAVCCEDGQHCCP 480
Query: 359 PGYHC 373
GY C
Sbjct: 481 AGYTC 485
Score = 46.6 bits (109), Expect = 3e-05
Identities = 21/50 (42%), Positives = 24/50 (48%)
Frame = +2
Query: 236 NCPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHCVTGG 385
NCP G +C L G CCPFS + C D CC G+HC T G
Sbjct: 52 NCPIG------HSCVLTAAGTAACCPFSQAMACGDGHHCCPYGFHCSTDG 95
>sp|P81013|GRN1_CYPCA Granulin-1
Length = 57
Score = 55.5 bits (132), Expect = 6e-08
Identities = 24/45 (53%), Positives = 26/45 (57%)
Frame = +2
Query: 239 CPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHC 373
CPDG TCCL G + CCPFS+G CC D CC GYHC
Sbjct: 10 CPDG------TTCCLSPYGVWYCCPFSMGQCCRDGIHCCRHGYHC 48
Score = 40.0 bits (92), Expect = 0.003
Identities = 13/31 (41%), Positives = 17/31 (54%)
Frame = +2
Query: 14 CCQYSNAVCCGDQLHCCPEGTTCDLVNKRCI 106
CC +S CC D +HCC G CD + C+
Sbjct: 26 CCPFSMGQCCRDGIHCCRHGYHCDSTSTHCL 56
>sp|P81015|GRN3_CYPCA Granulin-3
Length = 57
Score = 53.9 bits (128), Expect = 2e-07
Identities = 22/45 (48%), Positives = 24/45 (53%)
Frame = +2
Query: 239 CPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHC 373
C G C TCC G + CCPF +G CC D R CC GYHC
Sbjct: 4 CDAGITCPSGTTCCRSPFGVWYCCPFLMGQCCRDGRHCCRHGYHC 48
Score = 35.4 bits (80), Expect = 0.068
Identities = 12/31 (38%), Positives = 15/31 (48%)
Frame = +2
Query: 14 CCQYSNAVCCGDQLHCCPEGTTCDLVNKRCI 106
CC + CC D HCC G CD + C+
Sbjct: 26 CCPFLMGQCCRDGRHCCRHGYHCDSTSTLCL 56
>sp|P80930|ENA1_HORSE Antimicrobial peptide eNAP-1
Length = 46
Score = 53.9 bits (128), Expect = 2e-07
Identities = 21/43 (48%), Positives = 24/43 (55%)
Frame = +2
Query: 239 CPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGY 367
C +G C QTCC G CCP+S GVCC D R CC G+
Sbjct: 4 CGEGHFCHDXQTCCRASQGGXACCPYSQGVCCADQRHCCPVGF 46
Score = 45.4 bits (106), Expect = 7e-05
Identities = 16/24 (66%), Positives = 16/24 (66%)
Frame = +2
Query: 2 GGHQCCQYSNAVCCGDQLHCCPEG 73
GG CC YS VCC DQ HCCP G
Sbjct: 22 GGXACCPYSQGVCCADQRHCCPVG 45
>sp|P80059|PMD1_LOCMI Pars intercerebralis major peptide D1 (PMP-D1)
Length = 54
Score = 52.4 bits (124), Expect = 5e-07
Identities = 19/35 (54%), Positives = 22/35 (62%)
Frame = +2
Query: 2 GGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCI 106
G CC Y VCC D +HCCP GT CD ++RCI
Sbjct: 19 GEEGCCPYKEGVCCLDGIHCCPSGTVCDEDHRRCI 53
Score = 48.9 bits (115), Expect = 6e-06
Identities = 19/39 (48%), Positives = 21/39 (53%)
Frame = +2
Query: 257 CAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHC 373
C G +TCC G GCCP+ GVCC D CC G C
Sbjct: 7 CPGTETCCTTPQGEEGCCPYKEGVCCLDGIHCCPSGTVC 45
>sp|P81014|GRN2_CYPCA Granulin-2
Length = 57
Score = 48.9 bits (115), Expect = 6e-06
Identities = 19/39 (48%), Positives = 21/39 (53%)
Frame = +2
Query: 257 CAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHC 373
C TCC G + CCPF +G CC D R CC GY C
Sbjct: 10 CPSRTTCCRSPFGVWYCCPFLMGQCCRDGRHCCRHGYRC 48
Score = 35.8 bits (81), Expect = 0.052
Identities = 12/31 (38%), Positives = 15/31 (48%)
Frame = +2
Query: 14 CCQYSNAVCCGDQLHCCPEGTTCDLVNKRCI 106
CC + CC D HCC G CD + C+
Sbjct: 26 CCPFLMGQCCRDGRHCCRHGYRCDSTSTLCL 56
>sp|P25777|ORYB_ORYSA Oryzain beta chain precursor
Length = 471
Score = 43.5 bits (101), Expect = 3e-04
Identities = 19/50 (38%), Positives = 24/50 (48%), Gaps = 3/50 (6%)
Frame = +2
Query: 227 DKNNCPDGGQCA---GLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGY 367
D +CP G C G + CL++ GCCP CC D +CC P Y
Sbjct: 387 DNFSCPAGSTCCCAFGFRNLCLVW----GCCPVEGATCCKDHASCCPPDY 432
Score = 32.3 bits (72), Expect = 0.58
Identities = 13/39 (33%), Positives = 16/39 (41%), Gaps = 1/39 (2%)
Frame = +2
Query: 14 CCQYSNAVCCGDQLHCC-PEGTTCDLVNKRCIHQSNEPI 127
CC A CC D CC P+ C+ C N P+
Sbjct: 412 CCPVEGATCCKDHASCCPPDYPVCNTRAGTCSASKNSPL 450
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 57,838,752
Number of Sequences: 369166
Number of extensions: 1270157
Number of successful extensions: 4370
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3917
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4291
length of database: 68,354,980
effective HSP length: 101
effective length of database: 49,696,745
effective search space used: 2832714465
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)