Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_004_G05
(616 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P28797|GRN_CAVPO Granulins precursor (Proepithelin) (PEP... 102 8e-22
sp|P23785|GRN_RAT Granulins precursor [Contains: Acrogranin... 101 1e-21
sp|P28799|GRN_HUMAN Granulins precursor (Proepithelin) (PEP... 100 4e-21
sp|P28798|GRN_MOUSE Granulins precursor (Acrogranin) (Proep... 100 5e-21
sp|P80059|PMD1_LOCMI Pars intercerebralis major peptide D1 ... 59 1e-08
sp|P80930|ENA1_HORSE Antimicrobial peptide eNAP-1 54 2e-07
sp|P81013|GRN1_CYPCA Granulin-1 49 1e-05
sp|P81014|GRN2_CYPCA Granulin-2 45 1e-04
sp|P81015|GRN3_CYPCA Granulin-3 45 2e-04
sp|P25777|ORYB_ORYSA Oryzain beta chain precursor 41 0.003
>sp|P28797|GRN_CAVPO Granulins precursor (Proepithelin) (PEPI) [Contains: Acrogranin;
Granulin-1; Granulin-2; Granulin-3; Granulin-4;
Granulin-5; Granulin-6; Granulin-7]
Length = 591
Score = 102 bits (254), Expect = 8e-22
Identities = 55/157 (35%), Positives = 72/157 (45%), Gaps = 3/157 (1%)
Frame = +1
Query: 58 TPGLLKENLN---ICQNGKALCGDHKTCCASKSGGHQCCLYSNAVCCGDLLHCCPQRTTC 228
+PGLL L IC + ++ C D TCC SG + CC NA+CC D LHCCPQ T C
Sbjct: 194 SPGLLPAALPTSVICPDSRSQCPDDTTCCLLASGEYGCCPMPNAICCSDHLHCCPQDTVC 253
Query: 229 DLVNKRCIPHSNEPIEWPVVETFYSAKIETPKYTVQRNTFREFMINIGDISICPDGGQCA 408
DL RC+ + + + P +TV + + CP+G
Sbjct: 254 DLRQSRCLSQNKAK----------TLLTKLPSWTV-------WDVECDQEVSCPEG---- 292
Query: 409 GLHTCCFVYTVH*GCCPFSLGVCCPDLRTCCAPRYHC 519
TCC + + GCCPF VCC D CC R+ C
Sbjct: 293 --QTCCRLQSGKWGCCPFPKAVCCEDHVHCCPERFRC 327
Score = 87.8 bits (216), Expect = 2e-17
Identities = 48/141 (34%), Positives = 62/141 (43%), Gaps = 4/141 (2%)
Frame = +1
Query: 91 CQNGKALCGDHKTCCASKSGGHQCCLYSNAVCCGDLLHCCPQRTTCDLVNKRCIPH-SNE 267
C G+ C D TCC G CC A CC D +HCCP +CDLV+ RC+ +
Sbjct: 112 CPGGEFECPDSSTCCHMLDGSWGCCPMPQASCCEDRVHCCPHGASCDLVHIRCVTALGSH 171
Query: 268 PI--EWPVVETFYSAKIETPKYTVQRNTFREFMINIGDISICPDG-GQCAGLHTCCFVYT 438
P+ + P T Y+ TP + + ICPD QC TCC + +
Sbjct: 172 PLTTKLPAQRTNYTGAEGTPVVSPGL-----LPAALPTSVICPDSRSQCPDDTTCCLLAS 226
Query: 439 VH*GCCPFSLGVCCPDLRTCC 501
GCCP +CC D CC
Sbjct: 227 GEYGCCPMPNAICCSDHLHCC 247
Score = 80.9 bits (198), Expect = 2e-15
Identities = 47/154 (30%), Positives = 63/154 (40%)
Frame = +1
Query: 70 LKENLNICQNGKALCGDHKTCCASKSGGHQCCLYSNAVCCGDLLHCCPQRTTCDLVNKRC 249
L + ++ + A C +TCC GG CC +AVCC D HCCP TC++ + C
Sbjct: 433 LSQTTDVGCDQHASCPVRQTCCPKLGGGWACCQLPHAVCCEDGQHCCPAGYTCNVKARSC 492
Query: 250 IPHSNEPIEWPVVETFYSAKIETPKYTVQRNTFREFMINIGDISICPDGGQCAGLHTCCF 429
++ A + P + D++ C D C TCC
Sbjct: 493 EKAAD------------GAHLAAPLAVGSTG-------GVMDVA-CGDRHFCHDEQTCCR 532
Query: 430 VYTVH*GCCPFSLGVCCPDLRTCCAPRYHCVSGG 531
CCPF GVCC D R CC +HC S G
Sbjct: 533 DSRGGWACCPFHQGVCCKDQRHCCPAGFHCESQG 566
Score = 58.5 bits (140), Expect = 1e-08
Identities = 22/66 (33%), Positives = 31/66 (46%)
Frame = +1
Query: 82 LNICQNGKALCGDHKTCCASKSGGHQCCLYSNAVCCGDLLHCCPQRTTCDLVNKRCIPHS 261
+++ + C D +TCC GG CC + VCC D HCCP C+ RC+ H
Sbjct: 514 MDVACGDRHFCHDEQTCCRDSRGGWACCPFHQGVCCKDQRHCCPAGFHCESQGTRCV-HK 572
Query: 262 NEPIEW 279
+ W
Sbjct: 573 KSLLHW 578
Score = 57.4 bits (137), Expect = 3e-08
Identities = 35/123 (28%), Positives = 49/123 (39%)
Frame = +1
Query: 112 CGDHKTCCASKSGGHQCCLYSNAVCCGDLLHCCPQRTTCDLVNKRCIPHSNEPIEWPVVE 291
C + +TCC +SG CC + AVCC D +HCCP+R C C + W
Sbjct: 289 CPEGQTCCRLQSGKWGCCPFPKAVCCEDHVHCCPERFRCHTEKDTC-EQGLLQVPWAQKT 347
Query: 292 TFYSAKIETPKYTVQRNTFREFMINIGDISICPDGGQCAGLHTCCFVYTVH*GCCPFSLG 471
++ P +IS C + C + CC + + GCCP S G
Sbjct: 348 PAQPSRPSQPSPPGPPGPPSPPGPLRSEIS-CDEVVSCRPGNICCRLASGEWGCCPSSEG 406
Query: 472 VCC 480
C
Sbjct: 407 YLC 409
Score = 57.0 bits (136), Expect = 4e-08
Identities = 44/165 (26%), Positives = 56/165 (33%), Gaps = 1/165 (0%)
Frame = +1
Query: 28 CDILPHVFAKTPGLLKENLNICQNGKALCGDHKTCCASKSGGHQCCLYSNAVCCGDLLHC 207
CD P V +T L CQ+ A C +C + +G CC +S A+ CGD HC
Sbjct: 28 CD--PGVDLRTTALSGYLGRPCQS-PANCPIGHSCVLTAAGTAACCPFSQAMACGDGHHC 84
Query: 208 CPQRTTCDLVNKRCIPHSNEPIEWPVVETFYSAKIETPKYTVQRNTFREFMINIGDISIC 387
CP C CI + I++ C
Sbjct: 85 CPYGFHCSTDGGTCIQRPD--------------------------------IHLLGAVQC 112
Query: 388 PDGG-QCAGLHTCCFVYTVH*GCCPFSLGVCCPDLRTCCAPRYHC 519
P G +C TCC + GCCP CC D CC C
Sbjct: 113 PGGEFECPDSSTCCHMLDGSWGCCPMPQASCCEDRVHCCPHGASC 157
Score = 38.9 bits (89), Expect = 0.011
Identities = 16/49 (32%), Positives = 20/49 (40%)
Frame = +1
Query: 385 CPDGGQCAGLHTCCFVYTVH*GCCPFSLGVCCPDLRTCCAPRYHCVSGG 531
C C H+C CCPFS + C D CC +HC + G
Sbjct: 47 CQSPANCPIGHSCVLTAAGTAACCPFSQAMACGDGHHCCPYGFHCSTDG 95
>sp|P23785|GRN_RAT Granulins precursor [Contains: Acrogranin; Granulin-1 (Granulin G);
Granulin-2 (Granulin F); Granulin-3 (Granulin B)
(Epithelin-2); Granulin-4 (Granulin A) (Epithelin-1);
Granulin-5 (Granulin C); Granulin-6 (Granulin D);
Granulin-7 (Granulin E)]
Length = 588
Score = 101 bits (252), Expect = 1e-21
Identities = 54/146 (36%), Positives = 71/146 (48%), Gaps = 2/146 (1%)
Frame = +1
Query: 88 ICQNGKALCGDHKTCCASKSGGHQCCLYSNAVCCGDLLHCCPQRTTCDLVNKRCIPHSNE 267
+C + K C D TCC +G + CC NA+CC D LHCCPQ T CDL+ +CI
Sbjct: 205 VCPDAKTQCPDDSTCCELPTGKYGCCPMPNAICCSDHLHCCPQDTVCDLIQSKCISKD-- 262
Query: 268 PIEWPVVETFYSAKIET--PKYTVQRNTFREFMINIGDISICPDGGQCAGLHTCCFVYTV 441
Y+ + T P Y V E ++ ++S CPDG +TCC + T
Sbjct: 263 ----------YTTDLMTKLPGYPV-----NEVKCDL-EVS-CPDG------YTCCRLNTG 299
Query: 442 H*GCCPFSLGVCCPDLRTCCAPRYHC 519
GCCPF+ VCC D CC + C
Sbjct: 300 AWGCCPFTKAVCCEDHIHCCPAGFQC 325
Score = 86.7 bits (213), Expect = 4e-17
Identities = 47/139 (33%), Positives = 58/139 (41%), Gaps = 2/139 (1%)
Frame = +1
Query: 91 CQNGKALCGDHKTCCASKSGGHQCCLYSNAVCCGDLLHCCPQRTTCDLVNKRCI-PHSNE 267
C + C D TCC G CC A CC D +HCCP +CDLV+ RCI P
Sbjct: 125 CPGSQFECPDSATCCIMIDGSWGCCPMPQASCCEDRVHCCPHGASCDLVHTRCISPTGTH 184
Query: 268 PIEWPVVETFYSAKIETPKYTVQRNTFREFMINIGDISICPDG-GQCAGLHTCCFVYTVH 444
P+ K+ QR ++ +CPD QC TCC + T
Sbjct: 185 PL--------------LKKFPAQRTNRAVASFSV----VCPDAKTQCPDDSTCCELPTGK 226
Query: 445 *GCCPFSLGVCCPDLRTCC 501
GCCP +CC D CC
Sbjct: 227 YGCCPMPNAICCSDHLHCC 245
Score = 80.1 bits (196), Expect = 4e-15
Identities = 47/154 (30%), Positives = 63/154 (40%), Gaps = 6/154 (3%)
Frame = +1
Query: 88 ICQNGKALCGDH------KTCCASKSGGHQCCLYSNAVCCGDLLHCCPQRTTCDLVNKRC 249
+ Q+G C H +TCC S G CC +AVCC D HCCP TC++ + C
Sbjct: 433 LLQHGDIGCDQHTSCPVGQTCCPSLKGSWACCQLPHAVCCEDRQHCCPAGYTCNVKARTC 492
Query: 250 IPHSNEPIEWPVVETFYSAKIETPKYTVQRNTFREFMINIGDISICPDGGQCAGLHTCCF 429
E +VQ + F +G++ C G C +CC
Sbjct: 493 ---------------------EKDAGSVQPSMDLTFGSKVGNVE-CGAGHFCHDNQSCCK 530
Query: 430 VYTVH*GCCPFSLGVCCPDLRTCCAPRYHCVSGG 531
CCP+ GVCC D R CC +HC + G
Sbjct: 531 DSQGGWACCPYVKGVCCRDGRHCCPIGFHCSAKG 564
Score = 77.4 bits (189), Expect = 3e-14
Identities = 42/140 (30%), Positives = 61/140 (43%)
Frame = +1
Query: 112 CGDHKTCCASKSGGHQCCLYSNAVCCGDLLHCCPQRTTCDLVNKRCIPHSNEPIEWPVVE 291
C D TCC +G CC ++ AVCC D +HCCP C C ++ P ++
Sbjct: 287 CPDGYTCCRLNTGAWGCCPFTKAVCCEDHIHCCPAGFQCHTETGTC---ELGVLQVPWMK 343
Query: 292 TFYSAKIETPKYTVQRNTFREFMINIGDISICPDGGQCAGLHTCCFVYTVH*GCCPFSLG 471
+A + P + +N D+ C D C +TCC + + GCCP
Sbjct: 344 K-VTASLSLPDPQILKN----------DVP-CDDFSSCPSNNTCCRLSSGDWGCCPMPEA 391
Query: 472 VCCPDLRTCCAPRYHCVSGG 531
VCC D + CC + C+ G
Sbjct: 392 VCCLDHQHCCPQGFKCMDEG 411
Score = 58.5 bits (140), Expect = 1e-08
Identities = 37/136 (27%), Positives = 46/136 (33%)
Frame = +1
Query: 112 CGDHKTCCASKSGGHQCCLYSNAVCCGDLLHCCPQRTTCDLVNKRCIPHSNEPIEWPVVE 291
C D +C + SG CC +S V C D HCCP+ C K C S+ +
Sbjct: 67 CPDGYSCLLTVSGTSSCCPFSEGVSCDDGQHCCPRGFHCSADGKSCSQISDSLL------ 120
Query: 292 TFYSAKIETPKYTVQRNTFREFMINIGDISICPDGGQCAGLHTCCFVYTVH*GCCPFSLG 471
++ P G CPD TCC + GCCP
Sbjct: 121 ----GAVQCP----------------GSQFECPDSA------TCCIMIDGSWGCCPMPQA 154
Query: 472 VCCPDLRTCCAPRYHC 519
CC D CC C
Sbjct: 155 SCCEDRVHCCPHGASC 170
Score = 53.1 bits (126), Expect = 5e-07
Identities = 23/84 (27%), Positives = 36/84 (42%), Gaps = 9/84 (10%)
Frame = +1
Query: 28 CDILPHVFAKTPGLLKENLNICQNGKA---------LCGDHKTCCASKSGGHQCCLYSNA 180
C++ K G ++ ++++ K C D+++CC GG CC Y
Sbjct: 485 CNVKARTCEKDAGSVQPSMDLTFGSKVGNVECGAGHFCHDNQSCCKDSQGGWACCPYVKG 544
Query: 181 VCCGDLLHCCPQRTTCDLVNKRCI 252
VCC D HCCP C +C+
Sbjct: 545 VCCRDGRHCCPIGFHCSAKGTKCL 568
Score = 43.1 bits (100), Expect = 6e-04
Identities = 19/49 (38%), Positives = 25/49 (51%)
Frame = +1
Query: 385 CPDGGQCAGLHTCCFVYTVH*GCCPFSLGVCCPDLRTCCAPRYHCVSGG 531
CPDG ++C + CCPFS GV C D + CC +HC + G
Sbjct: 67 CPDG------YSCLLTVSGTSSCCPFSEGVSCDDGQHCCPRGFHCSADG 109
>sp|P28799|GRN_HUMAN Granulins precursor (Proepithelin) (PEPI) [Contains: Acrogranin;
Paragranulin; Granulin-1 (Granulin G); Granulin-2
(Granulin F); Granulin-3 (Granulin B); Granulin-4
(Granulin A); Granulin-5 (Granulin C); Granulin-6
(Granulin D); Granulin-7 (Granulin E)]
Length = 593
Score = 100 bits (248), Expect = 4e-21
Identities = 51/149 (34%), Positives = 68/149 (45%), Gaps = 5/149 (3%)
Frame = +1
Query: 88 ICQNGKALCGDHKTCCASKSGGHQCCLYSNAVCCGDLLHCCPQRTTCDLVNKRCIPHSNE 267
+C + ++ C D TCC SG + CC NA CC D LHCCPQ T CDL+ +C+ N
Sbjct: 207 MCPDARSRCPDGSTCCELPSGKYGCCPMPNATCCSDHLHCCPQDTVCDLIQSKCLSKENA 266
Query: 268 PIEWPVVETFYSAKIETPKYTVQRNTFREFMINIGDISI-----CPDGGQCAGLHTCCFV 432
+ + P +TV GD+ CPDG +TCC +
Sbjct: 267 TTD---------LLTKLPAHTV------------GDVKCDMEVSCPDG------YTCCRL 299
Query: 433 YTVH*GCCPFSLGVCCPDLRTCCAPRYHC 519
+ GCCPF+ VCC D CC + C
Sbjct: 300 QSGAWGCCPFTQAVCCEDHIHCCPAGFTC 328
Score = 87.8 bits (216), Expect = 2e-17
Identities = 56/176 (31%), Positives = 76/176 (43%)
Frame = +1
Query: 22 ALCDILPHVFAKTPGLLKENLNICQNGKALCGDHKTCCASKSGGHQCCLYSNAVCCGDLL 201
A D+L + A T G +K ++ + C D TCC +SG CC ++ AVCC D +
Sbjct: 266 ATTDLLTKLPAHTVGDVKCDMEVS------CPDGYTCCRLQSGAWGCCPFTQAVCCEDHI 319
Query: 202 HCCPQRTTCDLVNKRCIPHSNEPIEWPVVETFYSAKIETPKYTVQRNTFREFMINIGDIS 381
HCCP TCD C P + P +E A + P + D+
Sbjct: 320 HCCPAGFTCDTQKGTC---EQGPHQVPWMEK-APAHLSLPDPQALKR----------DVP 365
Query: 382 ICPDGGQCAGLHTCCFVYTVH*GCCPFSLGVCCPDLRTCCAPRYHCVSGGCA*LGS 549
C + C TCC + + GCCP VCC D + CC Y CV+ G GS
Sbjct: 366 -CDNVSSCPSSDTCCQLTSGEWGCCPIPEAVCCSDHQHCCPQGYTCVAEGQCQRGS 420
Score = 82.0 bits (201), Expect = 1e-15
Identities = 45/139 (32%), Positives = 56/139 (40%), Gaps = 2/139 (1%)
Frame = +1
Query: 91 CQNGKALCGDHKTCCASKSGGHQCCLYSNAVCCGDLLHCCPQRTTCDLVNKRCI-PHSNE 267
C + + C D TCC G CC A CC D +HCCP CDLV+ RCI P
Sbjct: 126 CPDSQFECPDFSTCCVMVDGSWGCCPMPQASCCEDRVHCCPHGAFCDLVHTRCITPTGTH 185
Query: 268 PIEWPVVETFYSAKIETPKYTVQRNTFREFMINIGDISICPDG-GQCAGLHTCCFVYTVH 444
P+ K QR + + +CPD +C TCC + +
Sbjct: 186 PL--------------AKKLPAQRT---NRAVALSSSVMCPDARSRCPDGSTCCELPSGK 228
Query: 445 *GCCPFSLGVCCPDLRTCC 501
GCCP CC D CC
Sbjct: 229 YGCCPMPNATCCSDHLHCC 247
Score = 80.9 bits (198), Expect = 2e-15
Identities = 45/142 (31%), Positives = 58/142 (40%), Gaps = 2/142 (1%)
Frame = +1
Query: 112 CGDHKTCCASKSGGHQCCLYSNAVCCGDLLHCCPQRTTCDLVNKRCIPHSNEPIEWPVVE 291
C +TCC S G CC +AVCC D HCCP TC++ + C
Sbjct: 450 CPVGQTCCPSLGGSWACCQLPHAVCCEDRQHCCPAGYTCNVKARSC-------------- 495
Query: 292 TFYSAKIETPKYTVQRNTF--REFMINIGDISICPDGGQCAGLHTCCFVYTVH*GCCPFS 465
E + Q TF R + + D+ C +G C TCC CCP+
Sbjct: 496 -------EKEVVSAQPATFLARSPHVGVKDVE-CGEGHFCHDNQTCCRDNRQGWACCPYR 547
Query: 466 LGVCCPDLRTCCAPRYHCVSGG 531
GVCC D R CC + C + G
Sbjct: 548 QGVCCADRRHCCPAGFRCAARG 569
Score = 62.8 bits (151), Expect = 7e-10
Identities = 42/156 (26%), Positives = 52/156 (33%), Gaps = 1/156 (0%)
Frame = +1
Query: 55 KTPGLLKENLNICQNGKALCGDHKTCCASKSGGHQCCLYSNAVCCGDLLHCCPQRTTCDL 234
K P L +L A C +C + SG CC + AV CGD HCCP+ C
Sbjct: 48 KWPTTLSRHLGGPCQVDAHCSAGHSCIFTVSGTSSCCPFPEAVACGDGHHCCPRGFHCSA 107
Query: 235 VNKRCIPHSNEPIEWPVVETFYSAKIETPKYTVQRNTFREFMINIGDISICPDGG-QCAG 411
+ C S ++G I CPD +C
Sbjct: 108 DGRSCFQRSGNN-------------------------------SVGAIQ-CPDSQFECPD 135
Query: 412 LHTCCFVYTVH*GCCPFSLGVCCPDLRTCCAPRYHC 519
TCC + GCCP CC D CC C
Sbjct: 136 FSTCCVMVDGSWGCCPMPQASCCEDRVHCCPHGAFC 171
Score = 53.1 bits (126), Expect = 5e-07
Identities = 22/63 (34%), Positives = 29/63 (46%), Gaps = 4/63 (6%)
Frame = +1
Query: 112 CGDHKTCCASKSGGHQCCLYSNAVCCGDLLHCCPQRTTCDLVNKRCI----PHSNEPIEW 279
C D++TCC G CC Y VCC D HCCP C +C+ P + P+
Sbjct: 527 CHDNQTCCRDNRQGWACCPYRQGVCCADRRHCCPAGFRCAARGTKCLRREAPRWDAPLRD 586
Query: 280 PVV 288
P +
Sbjct: 587 PAL 589
Score = 42.7 bits (99), Expect = 7e-04
Identities = 17/49 (34%), Positives = 22/49 (44%)
Frame = +1
Query: 385 CPDGGQCAGLHTCCFVYTVH*GCCPFSLGVCCPDLRTCCAPRYHCVSGG 531
C C+ H+C F + CCPF V C D CC +HC + G
Sbjct: 61 CQVDAHCSAGHSCIFTVSGTSSCCPFPEAVACGDGHHCCPRGFHCSADG 109
>sp|P28798|GRN_MOUSE Granulins precursor (Acrogranin) (Proepithelin) (PEPI) (PC
cell-derived growth factor) (PCDGF) [Contains: Granulin
1; Granulin 2; Granulin 3; Granulin 4; Granulin 5;
Granulin 6; Granulin 7]
Length = 589
Score = 99.8 bits (247), Expect = 5e-21
Identities = 52/146 (35%), Positives = 73/146 (50%), Gaps = 2/146 (1%)
Frame = +1
Query: 88 ICQNGKALCGDHKTCCASKSGGHQCCLYSNAVCCGDLLHCCPQRTTCDLVNKRCIPHSNE 267
+C + K C D TCC +G + CC NA+CC D LHCCPQ T CDL+ +C+ +
Sbjct: 206 VCPDAKTQCPDDSTCCELPTGKYGCCPMPNAICCSDHLHCCPQDTVCDLIQSKCLSKN-- 263
Query: 268 PIEWPVVETFYSAKIET--PKYTVQRNTFREFMINIGDISICPDGGQCAGLHTCCFVYTV 441
Y+ + T P Y V +E ++ ++S CP+G +TCC + T
Sbjct: 264 ----------YTTDLLTKLPGYPV-----KEVKCDM-EVS-CPEG------YTCCRLNTG 300
Query: 442 H*GCCPFSLGVCCPDLRTCCAPRYHC 519
GCCPF+ VCC D CC + C
Sbjct: 301 AWGCCPFAKAVCCEDHIHCCPAGFQC 326
Score = 84.0 bits (206), Expect = 3e-16
Identities = 44/138 (31%), Positives = 57/138 (41%), Gaps = 1/138 (0%)
Frame = +1
Query: 91 CQNGKALCGDHKTCCASKSGGHQCCLYSNAVCCGDLLHCCPQRTTCDLVNKRCIPHSNEP 270
C + C D TCC G CC A CC D +HCCP +CDLV+ RC+ +
Sbjct: 125 CPGSQFECPDSATCCIMVDGSWGCCPMPQASCCEDRVHCCPHGASCDLVHTRCVSPTGT- 183
Query: 271 IEWPVVETFYSAKIETPKYTVQRNTFREFMINIGDISICPDG-GQCAGLHTCCFVYTVH* 447
++ + P R F + +CPD QC TCC + T
Sbjct: 184 ---------HTLLKKFPAQKTNRAVSLPFSV------VCPDAKTQCPDDSTCCELPTGKY 228
Query: 448 GCCPFSLGVCCPDLRTCC 501
GCCP +CC D CC
Sbjct: 229 GCCPMPNAICCSDHLHCC 246
Score = 80.1 bits (196), Expect = 4e-15
Identities = 47/140 (33%), Positives = 62/140 (44%)
Frame = +1
Query: 112 CGDHKTCCASKSGGHQCCLYSNAVCCGDLLHCCPQRTTCDLVNKRCIPHSNEPIEWPVVE 291
C +TCC S G CC +AVCC D HCCP TC++ + C + I+ PV+
Sbjct: 448 CPVGQTCCPSLKGSWACCQLPHAVCCEDRQHCCPAGYTCNVKARTC-EKDVDFIQPPVLL 506
Query: 292 TFYSAKIETPKYTVQRNTFREFMINIGDISICPDGGQCAGLHTCCFVYTVH*GCCPFSLG 471
T PK +G++ C +G C TCC CCP+ G
Sbjct: 507 TL------GPK--------------VGNVE-CGEGHFCHDNQTCCKDSAGVWACCPYLKG 545
Query: 472 VCCPDLRTCCAPRYHCVSGG 531
VCC D R CC +HC + G
Sbjct: 546 VCCRDGRHCCPGGFHCSARG 565
Score = 76.3 bits (186), Expect = 6e-14
Identities = 39/140 (27%), Positives = 59/140 (42%)
Frame = +1
Query: 112 CGDHKTCCASKSGGHQCCLYSNAVCCGDLLHCCPQRTTCDLVNKRCIPHSNEPIEWPVVE 291
C + TCC +G CC ++ AVCC D +HCCP C C E +++
Sbjct: 288 CPEGYTCCRLNTGAWGCCPFAKAVCCEDHIHCCPAGFQCHTEKGTC--------EMGILQ 339
Query: 292 TFYSAKIETPKYTVQRNTFREFMINIGDISICPDGGQCAGLHTCCFVYTVH*GCCPFSLG 471
+ K+ P + + C D +C +TCC + + GCCP
Sbjct: 340 VPWMKKVIAPLRLPDPQILK-------SDTPCDDFTRCPTNNTCCKLNSGDWGCCPIPEA 392
Query: 472 VCCPDLRTCCAPRYHCVSGG 531
VCC D + CC + C++ G
Sbjct: 393 VCCSDNQHCCPQGFTCLAQG 412
Score = 69.7 bits (169), Expect = 6e-12
Identities = 43/137 (31%), Positives = 52/137 (37%), Gaps = 1/137 (0%)
Frame = +1
Query: 112 CGDHKTCCASKSGGHQCCLYSNAVCCGDLLHCCPQRTTCDLVNKRCIPHSNEPIEWPVVE 291
C + TCC SG CC AVCC D HCCPQ TC +
Sbjct: 370 CPTNNTCCKLNSGDWGCCPIPEAVCCSDNQHCCPQGFTC-------------------LA 410
Query: 292 TFYSAKIETPKYTVQRNTFREFM-INIGDISICPDGGQCAGLHTCCFVYTVH*GCCPFSL 468
Y K +T +++ R+ + IGDI C C TCC CC
Sbjct: 411 QGYCQKGDTMVAGLEKIPARQTTPLQIGDIG-CDQHTSCPVGQTCCPSLKGSWACCQLPH 469
Query: 469 GVCCPDLRTCCAPRYHC 519
VCC D + CC Y C
Sbjct: 470 AVCCEDRQHCCPAGYTC 486
Score = 65.1 bits (157), Expect = 1e-10
Identities = 39/136 (28%), Positives = 47/136 (34%)
Frame = +1
Query: 112 CGDHKTCCASKSGGHQCCLYSNAVCCGDLLHCCPQRTTCDLVNKRCIPHSNEPIEWPVVE 291
C +C + SG CC +S V CGD HCCPQ C K C S+ P+
Sbjct: 67 CPAGYSCLLTVSGTSSCCPFSKGVSCGDGYHCCPQGFHCSADGKSCFQMSDNPL------ 120
Query: 292 TFYSAKIETPKYTVQRNTFREFMINIGDISICPDGGQCAGLHTCCFVYTVH*GCCPFSLG 471
++ P G CPD TCC + GCCP
Sbjct: 121 ----GAVQCP----------------GSQFECPDSA------TCCIMVDGSWGCCPMPQA 154
Query: 472 VCCPDLRTCCAPRYHC 519
CC D CC C
Sbjct: 155 SCCEDRVHCCPHGASC 170
Score = 50.8 bits (120), Expect = 3e-06
Identities = 19/47 (40%), Positives = 24/47 (51%)
Frame = +1
Query: 112 CGDHKTCCASKSGGHQCCLYSNAVCCGDLLHCCPQRTTCDLVNKRCI 252
C D++TCC +G CC Y VCC D HCCP C +C+
Sbjct: 523 CHDNQTCCKDSAGVWACCPYLKGVCCRDGRHCCPGGFHCSARGTKCL 569
Score = 43.9 bits (102), Expect = 3e-04
Identities = 18/49 (36%), Positives = 23/49 (46%)
Frame = +1
Query: 385 CPDGGQCAGLHTCCFVYTVH*GCCPFSLGVCCPDLRTCCAPRYHCVSGG 531
C G C ++C + CCPFS GV C D CC +HC + G
Sbjct: 61 CQTHGHCPAGYSCLLTVSGTSSCCPFSKGVSCGDGYHCCPQGFHCSADG 109
>sp|P80059|PMD1_LOCMI Pars intercerebralis major peptide D1 (PMP-D1)
Length = 54
Score = 58.5 bits (140), Expect = 1e-08
Identities = 22/47 (46%), Positives = 27/47 (57%)
Frame = +1
Query: 112 CGDHKTCCASKSGGHQCCLYSNAVCCGDLLHCCPQRTTCDLVNKRCI 252
C +TCC + G CC Y VCC D +HCCP T CD ++RCI
Sbjct: 7 CPGTETCCTTPQGEEGCCPYKEGVCCLDGIHCCPSGTVCDEDHRRCI 53
Score = 40.8 bits (94), Expect = 0.003
Identities = 16/33 (48%), Positives = 17/33 (51%)
Frame = +1
Query: 403 CAGLHTCCFVYTVH*GCCPFSLGVCCPDLRTCC 501
C G TCC GCCP+ GVCC D CC
Sbjct: 7 CPGTETCCTTPQGEEGCCPYKEGVCCLDGIHCC 39
>sp|P80930|ENA1_HORSE Antimicrobial peptide eNAP-1
Length = 46
Score = 54.3 bits (129), Expect = 2e-07
Identities = 19/34 (55%), Positives = 21/34 (61%)
Frame = +1
Query: 112 CGDHKTCCASKSGGHQCCLYSNAVCCGDLLHCCP 213
C D +TCC + GG CC YS VCC D HCCP
Sbjct: 10 CHDXQTCCRASQGGXACCPYSQGVCCADQRHCCP 43
Score = 45.1 bits (105), Expect = 1e-04
Identities = 18/39 (46%), Positives = 20/39 (51%)
Frame = +1
Query: 385 CPDGGQCAGLHTCCFVYTVH*GCCPFSLGVCCPDLRTCC 501
C +G C TCC CCP+S GVCC D R CC
Sbjct: 4 CGEGHFCHDXQTCCRASQGGXACCPYSQGVCCADQRHCC 42
>sp|P81013|GRN1_CYPCA Granulin-1
Length = 57
Score = 48.9 bits (115), Expect = 1e-05
Identities = 19/48 (39%), Positives = 24/48 (50%)
Frame = +1
Query: 109 LCGDHKTCCASKSGGHQCCLYSNAVCCGDLLHCCPQRTTCDLVNKRCI 252
+C D TCC S G CC +S CC D +HCC CD + C+
Sbjct: 9 ICPDGTTCCLSPYGVWYCCPFSMGQCCRDGIHCCRHGYHCDSTSTHCL 56
Score = 47.8 bits (112), Expect = 2e-05
Identities = 25/56 (44%), Positives = 29/56 (51%)
Frame = +1
Query: 358 MINIGDISICPDGGQCAGLHTCCFVYTVH*GCCPFSLGVCCPDLRTCCAPRYHCVS 525
+I+ +ICPDG C C Y V CCPFS+G CC D CC YHC S
Sbjct: 1 VIHCDAATICPDGTTC-----CLSPYGVW-YCCPFSMGQCCRDGIHCCRHGYHCDS 50
>sp|P81014|GRN2_CYPCA Granulin-2
Length = 57
Score = 45.1 bits (105), Expect = 1e-04
Identities = 18/52 (34%), Positives = 22/52 (42%)
Frame = +1
Query: 97 NGKALCGDHKTCCASKSGGHQCCLYSNAVCCGDLLHCCPQRTTCDLVNKRCI 252
N + C TCC S G CC + CC D HCC CD + C+
Sbjct: 5 NARTTCPSRTTCCRSPFGVWYCCPFLMGQCCRDGRHCCRHGYRCDSTSTLCL 56
Score = 39.3 bits (90), Expect = 0.008
Identities = 18/41 (43%), Positives = 19/41 (46%)
Frame = +1
Query: 403 CAGLHTCCFVYTVH*GCCPFSLGVCCPDLRTCCAPRYHCVS 525
C TCC CCPF +G CC D R CC Y C S
Sbjct: 10 CPSRTTCCRSPFGVWYCCPFLMGQCCRDGRHCCRHGYRCDS 50
>sp|P81015|GRN3_CYPCA Granulin-3
Length = 57
Score = 44.7 bits (104), Expect = 2e-04
Identities = 21/50 (42%), Positives = 23/50 (46%)
Frame = +1
Query: 376 ISICPDGGQCAGLHTCCFVYTVH*GCCPFSLGVCCPDLRTCCAPRYHCVS 525
+ C G C TCC CCPF +G CC D R CC YHC S
Sbjct: 1 VVFCDAGITCPSGTTCCRSPFGVWYCCPFLMGQCCRDGRHCCRHGYHCDS 50
Score = 41.2 bits (95), Expect = 0.002
Identities = 17/47 (36%), Positives = 20/47 (42%)
Frame = +1
Query: 112 CGDHKTCCASKSGGHQCCLYSNAVCCGDLLHCCPQRTTCDLVNKRCI 252
C TCC S G CC + CC D HCC CD + C+
Sbjct: 10 CPSGTTCCRSPFGVWYCCPFLMGQCCRDGRHCCRHGYHCDSTSTLCL 56
>sp|P25777|ORYB_ORYSA Oryzain beta chain precursor
Length = 471
Score = 40.8 bits (94), Expect = 0.003
Identities = 18/46 (39%), Positives = 20/46 (43%), Gaps = 3/46 (6%)
Frame = +1
Query: 385 CPDGGQCA---GLHTCCFVYTVH*GCCPFSLGVCCPDLRTCCAPRY 513
CP G C G C V+ GCCP CC D +CC P Y
Sbjct: 391 CPAGSTCCCAFGFRNLCLVW----GCCPVEGATCCKDHASCCPPDY 432
Score = 30.8 bits (68), Expect = 2.9
Identities = 17/60 (28%), Positives = 21/60 (35%), Gaps = 6/60 (10%)
Frame = +1
Query: 112 CGDHKTCCASKSGGHQC-----CLYSNAVCCGDLLHCC-PQRTTCDLVNKRCIPHSNEPI 273
C TCC + + C C A CC D CC P C+ C N P+
Sbjct: 391 CPAGSTCCCAFGFRNLCLVWGCCPVEGATCCKDHASCCPPDYPVCNTRAGTCSASKNSPL 450
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 79,388,009
Number of Sequences: 369166
Number of extensions: 1819632
Number of successful extensions: 5538
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4934
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5467
length of database: 68,354,980
effective HSP length: 105
effective length of database: 48,957,805
effective search space used: 4846822695
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)