Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_014_N17
(439 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P28799|GRN_HUMAN Granulins precursor (Proepithelin) (PEP... 48 1e-05
sp|P28797|GRN_CAVPO Granulins precursor (Proepithelin) (PEP... 47 1e-05
sp|P23785|GRN_RAT Granulins precursor [Contains: Acrogranin... 47 1e-05
sp|P28798|GRN_MOUSE Granulins precursor (Acrogranin) (Proep... 47 2e-05
sp|P80059|PMD1_LOCMI Pars intercerebralis major peptide D1 ... 43 3e-04
sp|P81013|GRN1_CYPCA Granulin-1 33 0.35
sp|P43297|RD21A_ARATH Cysteine proteinase RD21a precursor (... 33 0.35
sp|P81014|GRN2_CYPCA Granulin-2 32 0.78
sp|P80930|ENA1_HORSE Antimicrobial peptide eNAP-1 32 0.78
sp|P81015|GRN3_CYPCA Granulin-3 31 1.0
>sp|P28799|GRN_HUMAN Granulins precursor (Proepithelin) (PEPI) [Contains: Acrogranin;
Paragranulin; Granulin-1 (Granulin G); Granulin-2
(Granulin F); Granulin-3 (Granulin B); Granulin-4
(Granulin A); Granulin-5 (Granulin C); Granulin-6
(Granulin D); Granulin-7 (Granulin E)]
Length = 593
Score = 47.8 bits (112), Expect = 1e-05
Identities = 15/29 (51%), Positives = 20/29 (68%)
Frame = +1
Query: 199 AVCCGDQLHCCPEGTTCDLVNKRCIHQSN 285
A CC D LHCCP+ T CDL+ +C+ + N
Sbjct: 237 ATCCSDHLHCCPQDTVCDLIQSKCLSKEN 265
Score = 45.1 bits (105), Expect = 7e-05
Identities = 16/26 (61%), Positives = 20/26 (76%)
Frame = +1
Query: 196 KAVCCGDQLHCCPEGTTCDLVNKRCI 273
+A CC D++HCCP G CDLV+ RCI
Sbjct: 154 QASCCEDRVHCCPHGAFCDLVHTRCI 179
Score = 42.7 bits (99), Expect = 3e-04
Identities = 17/37 (45%), Positives = 20/37 (54%)
Frame = +1
Query: 190 FFKAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEW 300
F +AVCC D +HCCP G TCD C Q + W
Sbjct: 309 FTQAVCCEDHIHCCPAGFTCDTQKGTC-EQGPHQVPW 344
Score = 38.1 bits (87), Expect = 0.008
Identities = 13/24 (54%), Positives = 17/24 (70%)
Frame = +1
Query: 199 AVCCGDQLHCCPEGTTCDLVNKRC 270
AVCC D+ HCCP G TC++ + C
Sbjct: 472 AVCCEDRQHCCPAGYTCNVKARSC 495
Score = 37.0 bits (84), Expect = 0.019
Identities = 12/18 (66%), Positives = 14/18 (77%)
Frame = +1
Query: 196 KAVCCGDQLHCCPEGTTC 249
+AVCC D HCCP+G TC
Sbjct: 393 EAVCCSDHQHCCPQGYTC 410
Score = 36.2 bits (82), Expect = 0.032
Identities = 14/31 (45%), Positives = 17/31 (54%)
Frame = +1
Query: 190 FFKAVCCGDQLHCCPEGTTCDLVNKRCIHQS 282
F +AV CGD HCCP G C + C +S
Sbjct: 86 FPEAVACGDGHHCCPRGFHCSADGRSCFQRS 116
Score = 35.0 bits (79), Expect = 0.071
Identities = 11/28 (39%), Positives = 16/28 (57%)
Frame = +1
Query: 196 KAVCCGDQLHCCPEGTTCDLVNKRCIHQ 279
+ VCC D+ HCCP G C +C+ +
Sbjct: 548 QGVCCADRRHCCPAGFRCAARGTKCLRR 575
>sp|P28797|GRN_CAVPO Granulins precursor (Proepithelin) (PEPI) [Contains: Acrogranin;
Granulin-1; Granulin-2; Granulin-3; Granulin-4;
Granulin-5; Granulin-6; Granulin-7]
Length = 591
Score = 47.4 bits (111), Expect = 1e-05
Identities = 16/28 (57%), Positives = 20/28 (71%)
Frame = +1
Query: 199 AVCCGDQLHCCPEGTTCDLVNKRCIHQS 282
A+CC D LHCCP+ T CDL RC+ Q+
Sbjct: 237 AICCSDHLHCCPQDTVCDLRQSRCLSQN 264
Score = 45.1 bits (105), Expect = 7e-05
Identities = 15/26 (57%), Positives = 21/26 (80%)
Frame = +1
Query: 196 KAVCCGDQLHCCPEGTTCDLVNKRCI 273
+A CC D++HCCP G +CDLV+ RC+
Sbjct: 140 QASCCEDRVHCCPHGASCDLVHIRCV 165
Score = 43.9 bits (102), Expect = 2e-04
Identities = 15/32 (46%), Positives = 20/32 (62%)
Frame = +1
Query: 190 FFKAVCCGDQLHCCPEGTTCDLVNKRCIHQSN 285
F + VCC DQ HCCP G C+ RC+H+ +
Sbjct: 543 FHQGVCCKDQRHCCPAGFHCESQGTRCVHKKS 574
Score = 37.0 bits (84), Expect = 0.019
Identities = 13/24 (54%), Positives = 16/24 (66%)
Frame = +1
Query: 199 AVCCGDQLHCCPEGTTCDLVNKRC 270
AVCC D HCCP G TC++ + C
Sbjct: 469 AVCCEDGQHCCPAGYTCNVKARSC 492
Score = 36.6 bits (83), Expect = 0.024
Identities = 14/27 (51%), Positives = 15/27 (55%)
Frame = +1
Query: 190 FFKAVCCGDQLHCCPEGTTCDLVNKRC 270
F KAVCC D +HCCPE C C
Sbjct: 308 FPKAVCCEDHVHCCPERFRCHTEKDTC 334
Score = 33.5 bits (75), Expect = 0.21
Identities = 13/30 (43%), Positives = 16/30 (53%)
Frame = +1
Query: 190 FFKAVCCGDQLHCCPEGTTCDLVNKRCIHQ 279
F +A+ CGD HCCP G C CI +
Sbjct: 72 FSQAMACGDGHHCCPYGFHCSTDGGTCIQR 101
>sp|P23785|GRN_RAT Granulins precursor [Contains: Acrogranin; Granulin-1 (Granulin G);
Granulin-2 (Granulin F); Granulin-3 (Granulin B)
(Epithelin-2); Granulin-4 (Granulin A) (Epithelin-1);
Granulin-5 (Granulin C); Granulin-6 (Granulin D);
Granulin-7 (Granulin E)]
Length = 588
Score = 47.4 bits (111), Expect = 1e-05
Identities = 15/25 (60%), Positives = 19/25 (76%)
Frame = +1
Query: 199 AVCCGDQLHCCPEGTTCDLVNKRCI 273
A+CC D LHCCP+ T CDL+ +CI
Sbjct: 235 AICCSDHLHCCPQDTVCDLIQSKCI 259
Score = 46.2 bits (108), Expect = 3e-05
Identities = 16/26 (61%), Positives = 21/26 (80%)
Frame = +1
Query: 196 KAVCCGDQLHCCPEGTTCDLVNKRCI 273
+A CC D++HCCP G +CDLV+ RCI
Sbjct: 153 QASCCEDRVHCCPHGASCDLVHTRCI 178
Score = 38.1 bits (87), Expect = 0.008
Identities = 14/27 (51%), Positives = 15/27 (55%)
Frame = +1
Query: 190 FFKAVCCGDQLHCCPEGTTCDLVNKRC 270
F KAVCC D +HCCP G C C
Sbjct: 306 FTKAVCCEDHIHCCPAGFQCHTETGTC 332
Score = 38.1 bits (87), Expect = 0.008
Identities = 13/24 (54%), Positives = 17/24 (70%)
Frame = +1
Query: 199 AVCCGDQLHCCPEGTTCDLVNKRC 270
AVCC D+ HCCP G TC++ + C
Sbjct: 469 AVCCEDRQHCCPAGYTCNVKARTC 492
Score = 35.4 bits (80), Expect = 0.054
Identities = 12/30 (40%), Positives = 16/30 (53%)
Frame = +1
Query: 190 FFKAVCCGDQLHCCPEGTTCDLVNKRCIHQ 279
+ K VCC D HCCP G C +C+ +
Sbjct: 541 YVKGVCCRDGRHCCPIGFHCSAKGTKCLRK 570
Score = 33.1 bits (74), Expect = 0.27
Identities = 11/18 (61%), Positives = 13/18 (72%)
Frame = +1
Query: 196 KAVCCGDQLHCCPEGTTC 249
+AVCC D HCCP+G C
Sbjct: 390 EAVCCLDHQHCCPQGFKC 407
Score = 32.0 bits (71), Expect = 0.60
Identities = 12/27 (44%), Positives = 13/27 (48%)
Frame = +1
Query: 190 FFKAVCCGDQLHCCPEGTTCDLVNKRC 270
F + V C D HCCP G C K C
Sbjct: 86 FSEGVSCDDGQHCCPRGFHCSADGKSC 112
>sp|P28798|GRN_MOUSE Granulins precursor (Acrogranin) (Proepithelin) (PEPI) (PC
cell-derived growth factor) (PCDGF) [Contains: Granulin
1; Granulin 2; Granulin 3; Granulin 4; Granulin 5;
Granulin 6; Granulin 7]
Length = 589
Score = 47.0 bits (110), Expect = 2e-05
Identities = 14/28 (50%), Positives = 21/28 (75%)
Frame = +1
Query: 199 AVCCGDQLHCCPEGTTCDLVNKRCIHQS 282
A+CC D LHCCP+ T CDL+ +C+ ++
Sbjct: 236 AICCSDHLHCCPQDTVCDLIQSKCLSKN 263
Score = 45.8 bits (107), Expect = 4e-05
Identities = 15/26 (57%), Positives = 21/26 (80%)
Frame = +1
Query: 196 KAVCCGDQLHCCPEGTTCDLVNKRCI 273
+A CC D++HCCP G +CDLV+ RC+
Sbjct: 153 QASCCEDRVHCCPHGASCDLVHTRCV 178
Score = 42.7 bits (99), Expect = 3e-04
Identities = 16/35 (45%), Positives = 19/35 (54%)
Frame = +1
Query: 190 FFKAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPI 294
F K V CGD HCCP+G C K C S+ P+
Sbjct: 86 FSKGVSCGDGYHCCPQGFHCSADGKSCFQMSDNPL 120
Score = 38.9 bits (89), Expect = 0.005
Identities = 17/40 (42%), Positives = 26/40 (65%)
Frame = +1
Query: 199 AVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVETI 318
AVCC D+ HCCP G TC++ + C + + I+ PV+ T+
Sbjct: 470 AVCCEDRQHCCPAGYTCNVKARTC-EKDVDFIQPPVLLTL 508
Score = 38.1 bits (87), Expect = 0.008
Identities = 14/27 (51%), Positives = 15/27 (55%)
Frame = +1
Query: 190 FFKAVCCGDQLHCCPEGTTCDLVNKRC 270
F KAVCC D +HCCP G C C
Sbjct: 307 FAKAVCCEDHIHCCPAGFQCHTEKGTC 333
Score = 37.0 bits (84), Expect = 0.019
Identities = 12/18 (66%), Positives = 14/18 (77%)
Frame = +1
Query: 196 KAVCCGDQLHCCPEGTTC 249
+AVCC D HCCP+G TC
Sbjct: 391 EAVCCSDNQHCCPQGFTC 408
Score = 35.8 bits (81), Expect = 0.041
Identities = 12/30 (40%), Positives = 16/30 (53%)
Frame = +1
Query: 190 FFKAVCCGDQLHCCPEGTTCDLVNKRCIHQ 279
+ K VCC D HCCP G C +C+ +
Sbjct: 542 YLKGVCCRDGRHCCPGGFHCSARGTKCLRK 571
>sp|P80059|PMD1_LOCMI Pars intercerebralis major peptide D1 (PMP-D1)
Length = 54
Score = 42.7 bits (99), Expect = 3e-04
Identities = 15/26 (57%), Positives = 19/26 (73%)
Frame = +1
Query: 196 KAVCCGDQLHCCPEGTTCDLVNKRCI 273
+ VCC D +HCCP GT CD ++RCI
Sbjct: 28 EGVCCLDGIHCCPSGTVCDEDHRRCI 53
>sp|P81013|GRN1_CYPCA Granulin-1
Length = 57
Score = 32.7 bits (73), Expect = 0.35
Identities = 11/28 (39%), Positives = 14/28 (50%)
Frame = +1
Query: 190 FFKAVCCGDQLHCCPEGTTCDLVNKRCI 273
F CC D +HCC G CD + C+
Sbjct: 29 FSMGQCCRDGIHCCRHGYHCDSTSTHCL 56
>sp|P43297|RD21A_ARATH Cysteine proteinase RD21a precursor (RD21)
Length = 462
Score = 32.7 bits (73), Expect = 0.35
Identities = 14/32 (43%), Positives = 15/32 (46%), Gaps = 1/32 (3%)
Frame = +1
Query: 199 AVCCGDQLHCCP-EGTTCDLVNKRCIHQSNEP 291
A CC D CCP E CDL C+ N P
Sbjct: 408 ATCCDDNYSCCPHEYPVCDLDQGTCLLSKNSP 439
>sp|P81014|GRN2_CYPCA Granulin-2
Length = 57
Score = 31.6 bits (70), Expect = 0.78
Identities = 11/28 (39%), Positives = 13/28 (46%)
Frame = +1
Query: 190 FFKAVCCGDQLHCCPEGTTCDLVNKRCI 273
F CC D HCC G CD + C+
Sbjct: 29 FLMGQCCRDGRHCCRHGYRCDSTSTLCL 56
>sp|P80930|ENA1_HORSE Antimicrobial peptide eNAP-1
Length = 46
Score = 31.6 bits (70), Expect = 0.78
Identities = 10/17 (58%), Positives = 12/17 (70%)
Frame = +1
Query: 190 FFKAVCCGDQLHCCPEG 240
+ + VCC DQ HCCP G
Sbjct: 29 YSQGVCCADQRHCCPVG 45
>sp|P81015|GRN3_CYPCA Granulin-3
Length = 57
Score = 31.2 bits (69), Expect = 1.0
Identities = 11/28 (39%), Positives = 13/28 (46%)
Frame = +1
Query: 190 FFKAVCCGDQLHCCPEGTTCDLVNKRCI 273
F CC D HCC G CD + C+
Sbjct: 29 FLMGQCCRDGRHCCRHGYHCDSTSTLCL 56
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 51,078,192
Number of Sequences: 369166
Number of extensions: 930346
Number of successful extensions: 2460
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 2370
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 2451
length of database: 68,354,980
effective HSP length: 100
effective length of database: 49,881,480
effective search space used: 2244666600
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)