Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_022_C07
(489 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P28797|GRN_CAVPO Granulins precursor (Proepithelin) (PEP... 98 9e-21
sp|P23785|GRN_RAT Granulins precursor [Contains: Acrogranin... 96 6e-20
sp|P28798|GRN_MOUSE Granulins precursor (Acrogranin) (Proep... 94 2e-19
sp|P28799|GRN_HUMAN Granulins precursor (Proepithelin) (PEP... 94 2e-19
sp|P80059|PMD1_LOCMI Pars intercerebralis major peptide D1 ... 64 2e-10
sp|P80930|ENA1_HORSE Antimicrobial peptide eNAP-1 59 5e-09
sp|P81013|GRN1_CYPCA Granulin-1 54 3e-07
sp|P81014|GRN2_CYPCA Granulin-2 50 3e-06
sp|P81015|GRN3_CYPCA Granulin-3 46 5e-05
sp|P43297|RD21A_ARATH Cysteine proteinase RD21a precursor (... 43 4e-04
>sp|P28797|GRN_CAVPO Granulins precursor (Proepithelin) (PEPI) [Contains: Acrogranin;
Granulin-1; Granulin-2; Granulin-3; Granulin-4;
Granulin-5; Granulin-6; Granulin-7]
Length = 591
Score = 98.2 bits (243), Expect = 9e-21
Identities = 49/138 (35%), Positives = 70/138 (50%), Gaps = 3/138 (2%)
Frame = +1
Query: 46 TPGLLKENLN---ICQNGKALCGDQKTCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTC 216
+PGLL L IC + ++ C D TCC SG + CC NA+CC D LHCCP+ T C
Sbjct: 194 SPGLLPAALPTSVICPDSRSQCPDDTTCCLLASGEYGCCPMPNAICCSDHLHCCPQDTVC 253
Query: 217 DLVNKRCIHQSNEPIEWPVVETIDSAKIETPKYTVERSTLREFMIKIGDKNNCPDGGQCA 396
DL RC+ Q+ + + P +TV + ++ + +CP+G
Sbjct: 254 DLRQSRCLSQNK----------AKTLLTKLPSWTV-------WDVECDQEVSCPEG---- 292
Query: 397 GLQTCCLMYTGHYGCCPF 450
QTCC + +G +GCCPF
Sbjct: 293 --QTCCRLQSGKWGCCPF 308
Score = 85.9 bits (211), Expect = 5e-17
Identities = 47/129 (36%), Positives = 63/129 (48%), Gaps = 6/129 (4%)
Frame = +1
Query: 79 CQNGKALCGDQKTCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQ-SNE 255
C G+ C D TCC G CC A CC D++HCCP G +CDLV+ RC+ +
Sbjct: 112 CPGGEFECPDSSTCCHMLDGSWGCCPMPQASCCEDRVHCCPHGASCDLVHIRCVTALGSH 171
Query: 256 PI--EWPVVETIDSAKIETPKYT--VERSTLREFMIKIGDKNNCPDG-GQCAGLQTCCLM 420
P+ + P T + TP + + + L +I CPD QC TCCL+
Sbjct: 172 PLTTKLPAQRTNYTGAEGTPVVSPGLLPAALPTSVI-------CPDSRSQCPDDTTCCLL 224
Query: 421 YTGHYGCCP 447
+G YGCCP
Sbjct: 225 ASGEYGCCP 233
Score = 73.9 bits (180), Expect = 2e-13
Identities = 42/131 (32%), Positives = 58/131 (44%)
Frame = +1
Query: 58 LKENLNICQNGKALCGDQKTCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRC 237
L + ++ + A C ++TCC GG CCQ +AVCC D HCCP G TC++ + C
Sbjct: 433 LSQTTDVGCDQHASCPVRQTCCPKLGGGWACCQLPHAVCCEDGQHCCPAGYTCNVKARSC 492
Query: 238 IHQSNEPIEWPVVETIDSAKIETPKYTVERSTLREFMIKIGDKNNCPDGGQCAGLQTCCL 417
+ D A + P ST + GD++ C D QTCC
Sbjct: 493 ------------EKAADGAHLAAP--LAVGSTGGVMDVACGDRHFCHDE------QTCCR 532
Query: 418 MYTGHYGCCPF 450
G + CCPF
Sbjct: 533 DSRGGWACCPF 543
Score = 67.4 bits (163), Expect = 2e-11
Identities = 23/61 (37%), Positives = 34/61 (55%)
Frame = +1
Query: 70 LNICQNGKALCGDQKTCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQS 249
+++ + C D++TCC GG CC + VCC DQ HCCP G C+ RC+H+
Sbjct: 514 MDVACGDRHFCHDEQTCCRDSRGGWACCPFHQGVCCKDQRHCCPAGFHCESQGTRCVHKK 573
Query: 250 N 252
+
Sbjct: 574 S 574
Score = 62.8 bits (151), Expect = 4e-10
Identities = 33/118 (27%), Positives = 48/118 (40%)
Frame = +1
Query: 100 CGDQKTCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVE 279
C + +TCC +SG CC + AVCC D +HCCPE C C Q + W
Sbjct: 289 CPEGQTCCRLQSGKWGCCPFPKAVCCEDHVHCCPERFRCHTEKDTC-EQGLLQVPWAQKT 347
Query: 280 TIDSAKIETPKYTVERSTLREFMIKIGDKNNCPDGGQCAGLQTCCLMYTGHYGCCPFS 453
++ P + + +C + C CC + +G +GCCP S
Sbjct: 348 PAQPSRPSQPSPPGPPGPPSP-PGPLRSEISCDEVVSCRPGNICCRLASGEWGCCPSS 404
Score = 57.8 bits (138), Expect = 1e-08
Identities = 35/124 (28%), Positives = 48/124 (38%), Gaps = 1/124 (0%)
Frame = +1
Query: 79 CQNGKALCGDQKTCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEP 258
CQ+ A C +C + +G CC +S A+ CGD HCCP G C CI +
Sbjct: 47 CQS-PANCPIGHSCVLTAAGTAACCPFSQAMACGDGHHCCPYGFHCSTDGGTCIQR---- 101
Query: 259 IEWPVVETIDSAKIETPKYTVERSTLREFMIKIGDKNNCPDGG-QCAGLQTCCLMYTGHY 435
P + + + + CP G +C TCC M G +
Sbjct: 102 ---PDIHLLGAVQ-------------------------CPGGEFECPDSSTCCHMLDGSW 133
Query: 436 GCCP 447
GCCP
Sbjct: 134 GCCP 137
>sp|P23785|GRN_RAT Granulins precursor [Contains: Acrogranin; Granulin-1 (Granulin G);
Granulin-2 (Granulin F); Granulin-3 (Granulin B)
(Epithelin-2); Granulin-4 (Granulin A) (Epithelin-1);
Granulin-5 (Granulin C); Granulin-6 (Granulin D);
Granulin-7 (Granulin E)]
Length = 588
Score = 95.5 bits (236), Expect = 6e-20
Identities = 44/126 (34%), Positives = 61/126 (48%)
Frame = +1
Query: 76 ICQNGKALCGDQKTCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNE 255
+C + K C D TCC +G + CC NA+CC D LHCCP+ T CDL+ +CI +
Sbjct: 205 VCPDAKTQCPDDSTCCELPTGKYGCCPMPNAICCSDHLHCCPQDTVCDLIQSKCISK--- 261
Query: 256 PIEWPVVETIDSAKIETPKYTVERSTLREFMIKIGDKNNCPDGGQCAGLQTCCLMYTGHY 435
+ + P Y V +K + +CPDG TCC + TG +
Sbjct: 262 -------DYTTDLMTKLPGYPVNE-------VKCDLEVSCPDG------YTCCRLNTGAW 301
Query: 436 GCCPFS 453
GCCPF+
Sbjct: 302 GCCPFT 307
Score = 83.6 bits (205), Expect = 2e-16
Identities = 42/123 (34%), Positives = 56/123 (45%)
Frame = +1
Query: 79 CQNGKALCGDQKTCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEP 258
C + C D TCC G CC A CC D++HCCP G +CDLV+ RCI +
Sbjct: 125 CPGSQFECPDSATCCIMIDGSWGCCPMPQASCCEDRVHCCPHGASCDLVHTRCISPTG-- 182
Query: 259 IEWPVVETIDSAKIETPKYTVERSTLREFMIKIGDKNNCPDGGQCAGLQTCCLMYTGHYG 438
P+++ + P R+ ++ K CPD TCC + TG YG
Sbjct: 183 -THPLLK-------KFPAQRTNRAVASFSVVCPDAKTQCPDD------STCCELPTGKYG 228
Query: 439 CCP 447
CCP
Sbjct: 229 CCP 231
Score = 70.1 bits (170), Expect = 3e-12
Identities = 34/116 (29%), Positives = 52/116 (44%)
Frame = +1
Query: 100 CGDQKTCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVE 279
C D TCC +G CC ++ AVCC D +HCCP G C C ++ P ++
Sbjct: 287 CPDGYTCCRLNTGAWGCCPFTKAVCCEDHIHCCPAGFQCHTETGTC---ELGVLQVPWMK 343
Query: 280 TIDSAKIETPKYTVERSTLREFMIKIGDKNNCPDGGQCAGLQTCCLMYTGHYGCCP 447
+ +A + P + ++ + C D C TCC + +G +GCCP
Sbjct: 344 KV-TASLSLPDPQILKNDV-----------PCDDFSSCPSNNTCCRLSSGDWGCCP 387
Score = 69.3 bits (168), Expect = 4e-12
Identities = 38/117 (32%), Positives = 51/117 (43%)
Frame = +1
Query: 100 CGDQKTCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVE 279
C +TCC S G CCQ +AVCC D+ HCCP G TC++ + C
Sbjct: 447 CPVGQTCCPSLKGSWACCQLPHAVCCEDRQHCCPAGYTCNVKARTC-------------- 492
Query: 280 TIDSAKIETPKYTVERSTLREFMIKIGDKNNCPDGGQCAGLQTCCLMYTGHYGCCPF 450
E +V+ S F K+G+ C G C Q+CC G + CCP+
Sbjct: 493 -------EKDAGSVQPSMDLTFGSKVGNV-ECGAGHFCHDNQSCCKDSQGGWACCPY 541
Score = 62.0 bits (149), Expect = 7e-10
Identities = 34/116 (29%), Positives = 44/116 (37%)
Frame = +1
Query: 100 CGDQKTCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVE 279
C D +C + SG CC +S V C D HCCP G C K C S+ +
Sbjct: 67 CPDGYSCLLTVSGTSSCCPFSEGVSCDDGQHCCPRGFHCSADGKSCSQISDSLL------ 120
Query: 280 TIDSAKIETPKYTVERSTLREFMIKIGDKNNCPDGGQCAGLQTCCLMYTGHYGCCP 447
++ P G + CPD TCC+M G +GCCP
Sbjct: 121 ----GAVQCP----------------GSQFECPDSA------TCCIMIDGSWGCCP 150
Score = 60.1 bits (144), Expect = 3e-09
Identities = 25/86 (29%), Positives = 37/86 (43%), Gaps = 9/86 (10%)
Frame = +1
Query: 16 CNILQHVIAKTPGLLKENLNICQNGKA---------LCGDQKTCCASKSGGHQCCQYSNA 168
CN+ K G ++ ++++ K C D ++CC GG CC Y
Sbjct: 485 CNVKARTCEKDAGSVQPSMDLTFGSKVGNVECGAGHFCHDNQSCCKDSQGGWACCPYVKG 544
Query: 169 VCCGDQLHCCPEGTTCDLVNKRCIHQ 246
VCC D HCCP G C +C+ +
Sbjct: 545 VCCRDGRHCCPIGFHCSAKGTKCLRK 570
Score = 57.4 bits (137), Expect = 2e-08
Identities = 35/115 (30%), Positives = 44/115 (38%)
Frame = +1
Query: 100 CGDQKTCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVE 279
C TCC SG CC AVCC D HCCP+G C ++ +
Sbjct: 369 CPSNNTCCRLSSGDWGCCPMPEAVCCLDHQHCCPQGFKC--------------MDEGYCQ 414
Query: 280 TIDSAKIETPKYTVERSTLREFMIKIGDKNNCPDGGQCAGLQTCCLMYTGHYGCC 444
D K V ++TL ++ GD C C QTCC G + CC
Sbjct: 415 KGDRMVAGLEKMPVRQTTL----LQHGD-IGCDQHTSCPVGQTCCPSLKGSWACC 464
Score = 28.9 bits (63), Expect = 6.7
Identities = 12/30 (40%), Positives = 17/30 (56%)
Frame = +1
Query: 364 KNNCPDGGQCAGLQTCCLMYTGHYGCCPFS 453
+++CPDG +C L +G CCPFS
Sbjct: 64 RDHCPDG------YSCLLTVSGTSSCCPFS 87
>sp|P28798|GRN_MOUSE Granulins precursor (Acrogranin) (Proepithelin) (PEPI) (PC
cell-derived growth factor) (PCDGF) [Contains: Granulin
1; Granulin 2; Granulin 3; Granulin 4; Granulin 5;
Granulin 6; Granulin 7]
Length = 589
Score = 93.6 bits (231), Expect = 2e-19
Identities = 44/126 (34%), Positives = 64/126 (50%)
Frame = +1
Query: 76 ICQNGKALCGDQKTCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNE 255
+C + K C D TCC +G + CC NA+CC D LHCCP+ T CDL+ +C+ ++
Sbjct: 206 VCPDAKTQCPDDSTCCELPTGKYGCCPMPNAICCSDHLHCCPQDTVCDLIQSKCLSKN-- 263
Query: 256 PIEWPVVETIDSAKIETPKYTVERSTLREFMIKIGDKNNCPDGGQCAGLQTCCLMYTGHY 435
T D + P Y V+ +K + +CP+G TCC + TG +
Sbjct: 264 -------YTTD-LLTKLPGYPVKE-------VKCDMEVSCPEG------YTCCRLNTGAW 302
Query: 436 GCCPFS 453
GCCPF+
Sbjct: 303 GCCPFA 308
Score = 84.0 bits (206), Expect = 2e-16
Identities = 42/124 (33%), Positives = 54/124 (43%), Gaps = 1/124 (0%)
Frame = +1
Query: 79 CQNGKALCGDQKTCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEP 258
C + C D TCC G CC A CC D++HCCP G +CDLV+ RC+ +
Sbjct: 125 CPGSQFECPDSATCCIMVDGSWGCCPMPQASCCEDRVHCCPHGASCDLVHTRCVSPTG-- 182
Query: 259 IEWPVVETIDSAKIETPKYTVERSTLREFMIKIGD-KNNCPDGGQCAGLQTCCLMYTGHY 435
+ + P R+ F + D K CPD TCC + TG Y
Sbjct: 183 --------THTLLKKFPAQKTNRAVSLPFSVVCPDAKTQCPDD------STCCELPTGKY 228
Query: 436 GCCP 447
GCCP
Sbjct: 229 GCCP 232
Score = 72.4 bits (176), Expect = 5e-13
Identities = 39/117 (33%), Positives = 55/117 (47%)
Frame = +1
Query: 100 CGDQKTCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVE 279
C +TCC S G CCQ +AVCC D+ HCCP G TC++ + C + + I+ PV+
Sbjct: 448 CPVGQTCCPSLKGSWACCQLPHAVCCEDRQHCCPAGYTCNVKARTC-EKDVDFIQPPVLL 506
Query: 280 TIDSAKIETPKYTVERSTLREFMIKIGDKNNCPDGGQCAGLQTCCLMYTGHYGCCPF 450
T+ K+G+ C +G C QTCC G + CCP+
Sbjct: 507 TLGP--------------------KVGNV-ECGEGHFCHDNQTCCKDSAGVWACCPY 542
Score = 70.5 bits (171), Expect = 2e-12
Identities = 38/143 (26%), Positives = 59/143 (41%)
Frame = +1
Query: 19 NILQHVIAKTPGLLKENLNICQNGKALCGDQKTCCASKSGGHQCCQYSNAVCCGDQLHCC 198
N ++ K PG + + + + C + TCC +G CC ++ AVCC D +HCC
Sbjct: 263 NYTTDLLTKLPGYPVKEVKC--DMEVSCPEGYTCCRLNTGAWGCCPFAKAVCCEDHIHCC 320
Query: 199 PEGTTCDLVNKRCIHQSNEPIEWPVVETIDSAKIETPKYTVERSTLREFMIKIGDKNNCP 378
P G C H E +++ K+ P + L+ C
Sbjct: 321 PAGFQC--------HTEKGTCEMGILQVPWMKKVIAPLRLPDPQILK-------SDTPCD 365
Query: 379 DGGQCAGLQTCCLMYTGHYGCCP 447
D +C TCC + +G +GCCP
Sbjct: 366 DFTRCPTNNTCCKLNSGDWGCCP 388
Score = 68.6 bits (166), Expect = 8e-12
Identities = 35/116 (30%), Positives = 46/116 (39%)
Frame = +1
Query: 100 CGDQKTCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVE 279
C +C + SG CC +S V CGD HCCP+G C K C S+ P+
Sbjct: 67 CPAGYSCLLTVSGTSSCCPFSKGVSCGDGYHCCPQGFHCSADGKSCFQMSDNPL------ 120
Query: 280 TIDSAKIETPKYTVERSTLREFMIKIGDKNNCPDGGQCAGLQTCCLMYTGHYGCCP 447
++ P G + CPD TCC+M G +GCCP
Sbjct: 121 ----GAVQCP----------------GSQFECPDSA------TCCIMVDGSWGCCP 150
Score = 61.6 bits (148), Expect = 9e-10
Identities = 38/116 (32%), Positives = 46/116 (39%), Gaps = 1/116 (0%)
Frame = +1
Query: 100 CGDQKTCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVE 279
C TCC SG CC AVCC D HCCP+G TC L C
Sbjct: 370 CPTNNTCCKLNSGDWGCCPIPEAVCCSDNQHCCPQGFTC-LAQGYC-------------- 414
Query: 280 TIDSAKIETPKYTVERSTLREFM-IKIGDKNNCPDGGQCAGLQTCCLMYTGHYGCC 444
K +T +E+ R+ ++IGD C C QTCC G + CC
Sbjct: 415 ----QKGDTMVAGLEKIPARQTTPLQIGD-IGCDQHTSCPVGQTCCPSLKGSWACC 465
Score = 55.5 bits (132), Expect = 7e-08
Identities = 20/49 (40%), Positives = 25/49 (51%)
Frame = +1
Query: 100 CGDQKTCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQ 246
C D +TCC +G CC Y VCC D HCCP G C +C+ +
Sbjct: 523 CHDNQTCCKDSAGVWACCPYLKGVCCRDGRHCCPGGFHCSARGTKCLRK 571
Score = 29.3 bits (64), Expect = 5.1
Identities = 11/28 (39%), Positives = 14/28 (50%)
Frame = +1
Query: 370 NCPDGGQCAGLQTCCLMYTGHYGCCPFS 453
+C G C +C L +G CCPFS
Sbjct: 60 SCQTHGHCPAGYSCLLTVSGTSSCCPFS 87
>sp|P28799|GRN_HUMAN Granulins precursor (Proepithelin) (PEPI) [Contains: Acrogranin;
Paragranulin; Granulin-1 (Granulin G); Granulin-2
(Granulin F); Granulin-3 (Granulin B); Granulin-4
(Granulin A); Granulin-5 (Granulin C); Granulin-6
(Granulin D); Granulin-7 (Granulin E)]
Length = 593
Score = 93.6 bits (231), Expect = 2e-19
Identities = 43/126 (34%), Positives = 63/126 (50%)
Frame = +1
Query: 76 ICQNGKALCGDQKTCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNE 255
+C + ++ C D TCC SG + CC NA CC D LHCCP+ T CDL+ +C+ + N
Sbjct: 207 MCPDARSRCPDGSTCCELPSGKYGCCPMPNATCCSDHLHCCPQDTVCDLIQSKCLSKENA 266
Query: 256 PIEWPVVETIDSAKIETPKYTVERSTLREFMIKIGDKNNCPDGGQCAGLQTCCLMYTGHY 435
+ + P +TV +K + +CPDG TCC + +G +
Sbjct: 267 TTD---------LLTKLPAHTVGD-------VKCDMEVSCPDG------YTCCRLQSGAW 304
Query: 436 GCCPFS 453
GCCPF+
Sbjct: 305 GCCPFT 310
Score = 83.2 bits (204), Expect = 3e-16
Identities = 44/124 (35%), Positives = 57/124 (45%), Gaps = 1/124 (0%)
Frame = +1
Query: 79 CQNGKALCGDQKTCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEP 258
C + + C D TCC G CC A CC D++HCCP G CDLV+ RCI +
Sbjct: 126 CPDSQFECPDFSTCCVMVDGSWGCCPMPQASCCEDRVHCCPHGAFCDLVHTRCITPTG-- 183
Query: 259 IEWPVVETIDSAKIETPKYTVERSTLREFMIKIGD-KNNCPDGGQCAGLQTCCLMYTGHY 435
T AK + P R+ + D ++ CPDG TCC + +G Y
Sbjct: 184 -------THPLAK-KLPAQRTNRAVALSSSVMCPDARSRCPDG------STCCELPSGKY 229
Query: 436 GCCP 447
GCCP
Sbjct: 230 GCCP 233
Score = 77.0 bits (188), Expect = 2e-14
Identities = 43/146 (29%), Positives = 63/146 (43%)
Frame = +1
Query: 10 ALCNILQHVIAKTPGLLKENLNICQNGKALCGDQKTCCASKSGGHQCCQYSNAVCCGDQL 189
A ++L + A T G +K ++ + C D TCC +SG CC ++ AVCC D +
Sbjct: 266 ATTDLLTKLPAHTVGDVKCDMEVS------CPDGYTCCRLQSGAWGCCPFTQAVCCEDHI 319
Query: 190 HCCPEGTTCDLVNKRCIHQSNEPIEWPVVETIDSAKIETPKYTVERSTLREFMIKIGDKN 369
HCCP G TCD C P + P +E + ++R
Sbjct: 320 HCCPAGFTCDTQKGTC---EQGPHQVPWMEKAPAHLSLPDPQALKRDV------------ 364
Query: 370 NCPDGGQCAGLQTCCLMYTGHYGCCP 447
C + C TCC + +G +GCCP
Sbjct: 365 PCDNVSSCPSSDTCCQLTSGEWGCCP 390
Score = 67.0 bits (162), Expect = 2e-11
Identities = 36/118 (30%), Positives = 50/118 (42%), Gaps = 1/118 (0%)
Frame = +1
Query: 100 CGDQKTCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVE 279
C +TCC S G CCQ +AVCC D+ HCCP G TC++ + C
Sbjct: 450 CPVGQTCCPSLGGSWACCQLPHAVCCEDRQHCCPAGYTCNVKARSC-------------- 495
Query: 280 TIDSAKIETPKYTVERSTLREFMIKIGDKN-NCPDGGQCAGLQTCCLMYTGHYGCCPF 450
E + + +T +G K+ C +G C QTCC + CCP+
Sbjct: 496 -------EKEVVSAQPATFLARSPHVGVKDVECGEGHFCHDNQTCCRDNRQGWACCPY 546
Score = 63.2 bits (152), Expect = 3e-10
Identities = 37/139 (26%), Positives = 49/139 (35%), Gaps = 1/139 (0%)
Frame = +1
Query: 34 VIAKTPGLLKENLNICQNGKALCGDQKTCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTT 213
++ K P L +L A C +C + SG CC + AV CGD HCCP G
Sbjct: 45 LLDKWPTTLSRHLGGPCQVDAHCSAGHSCIFTVSGTSSCCPFPEAVACGDGHHCCPRGFH 104
Query: 214 CDLVNKRCIHQSNEPIEWPVVETIDSAKIETPKYTVERSTLREFMIKIGDKNNCPDGG-Q 390
C + C +S + CPD +
Sbjct: 105 CSADGRSCFQRSGNNSVGAI--------------------------------QCPDSQFE 132
Query: 391 CAGLQTCCLMYTGHYGCCP 447
C TCC+M G +GCCP
Sbjct: 133 CPDFSTCCVMVDGSWGCCP 151
Score = 61.2 bits (147), Expect = 1e-09
Identities = 41/138 (29%), Positives = 54/138 (39%)
Frame = +1
Query: 31 HVIAKTPGLLKENLNICQNGKALCGDQKTCCASKSGGHQCCQYSNAVCCGDQLHCCPEGT 210
H+ P LK ++ C N + C TCC SG CC AVCC D HCCP+G
Sbjct: 351 HLSLPDPQALKRDVP-CDNVSS-CPSSDTCCQLTSGEWGCCPIPEAVCCSDHQHCCPQGY 408
Query: 211 TCDLVNKRCIHQSNEPIEWPVVETIDSAKIETPKYTVERSTLREFMIKIGDKNNCPDGGQ 390
TC + +C S +V ++ + R I +CP G
Sbjct: 409 TC-VAEGQCQRGSE------IVAGLEKMPARRASLSHPRD------IGCDQHTSCPVG-- 453
Query: 391 CAGLQTCCLMYTGHYGCC 444
QTCC G + CC
Sbjct: 454 ----QTCCPSLGGSWACC 467
Score = 57.4 bits (137), Expect = 2e-08
Identities = 20/49 (40%), Positives = 25/49 (51%)
Frame = +1
Query: 100 CGDQKTCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQ 246
C D +TCC G CC Y VCC D+ HCCP G C +C+ +
Sbjct: 527 CHDNQTCCRDNRQGWACCPYRQGVCCADRRHCCPAGFRCAARGTKCLRR 575
>sp|P80059|PMD1_LOCMI Pars intercerebralis major peptide D1 (PMP-D1)
Length = 54
Score = 63.5 bits (153), Expect = 2e-10
Identities = 23/47 (48%), Positives = 28/47 (59%)
Frame = +1
Query: 100 CGDQKTCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCI 240
C +TCC + G CC Y VCC D +HCCP GT CD ++RCI
Sbjct: 7 CPGTETCCTTPQGEEGCCPYKEGVCCLDGIHCCPSGTVCDEDHRRCI 53
Score = 31.6 bits (70), Expect = 1.0
Identities = 10/20 (50%), Positives = 12/20 (60%)
Frame = +1
Query: 391 CAGLQTCCLMYTGHYGCCPF 450
C G +TCC G GCCP+
Sbjct: 7 CPGTETCCTTPQGEEGCCPY 26
>sp|P80930|ENA1_HORSE Antimicrobial peptide eNAP-1
Length = 46
Score = 59.3 bits (142), Expect = 5e-09
Identities = 21/36 (58%), Positives = 23/36 (63%)
Frame = +1
Query: 100 CGDQKTCCASKSGGHQCCQYSNAVCCGDQLHCCPEG 207
C D +TCC + GG CC YS VCC DQ HCCP G
Sbjct: 10 CHDXQTCCRASQGGXACCPYSQGVCCADQRHCCPVG 45
Score = 32.3 bits (72), Expect = 0.61
Identities = 12/27 (44%), Positives = 14/27 (51%)
Frame = +1
Query: 373 CPDGGQCAGLQTCCLMYTGHYGCCPFS 453
C +G C QTCC G CCP+S
Sbjct: 4 CGEGHFCHDXQTCCRASQGGXACCPYS 30
>sp|P81013|GRN1_CYPCA Granulin-1
Length = 57
Score = 53.5 bits (127), Expect = 3e-07
Identities = 20/48 (41%), Positives = 25/48 (52%)
Frame = +1
Query: 97 LCGDQKTCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCI 240
+C D TCC S G CC +S CC D +HCC G CD + C+
Sbjct: 9 ICPDGTTCCLSPYGVWYCCPFSMGQCCRDGIHCCRHGYHCDSTSTHCL 56
Score = 31.6 bits (70), Expect = 1.0
Identities = 14/28 (50%), Positives = 16/28 (57%)
Frame = +1
Query: 373 CPDGGQCAGLQTCCLMYTGHYGCCPFSL 456
CPDG TCCL G + CCPFS+
Sbjct: 10 CPDG------TTCCLSPYGVWYCCPFSM 31
>sp|P81014|GRN2_CYPCA Granulin-2
Length = 57
Score = 50.1 bits (118), Expect = 3e-06
Identities = 19/52 (36%), Positives = 24/52 (46%)
Frame = +1
Query: 85 NGKALCGDQKTCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCI 240
N + C + TCC S G CC + CC D HCC G CD + C+
Sbjct: 5 NARTTCPSRTTCCRSPFGVWYCCPFLMGQCCRDGRHCCRHGYRCDSTSTLCL 56
>sp|P81015|GRN3_CYPCA Granulin-3
Length = 57
Score = 45.8 bits (107), Expect = 5e-05
Identities = 18/47 (38%), Positives = 21/47 (44%)
Frame = +1
Query: 100 CGDQKTCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCI 240
C TCC S G CC + CC D HCC G CD + C+
Sbjct: 10 CPSGTTCCRSPFGVWYCCPFLMGQCCRDGRHCCRHGYHCDSTSTLCL 56
>sp|P43297|RD21A_ARATH Cysteine proteinase RD21a precursor (RD21)
Length = 462
Score = 42.7 bits (99), Expect = 4e-04
Identities = 21/59 (35%), Positives = 23/59 (38%), Gaps = 6/59 (10%)
Frame = +1
Query: 100 CGDQKTCCASKSGGHQC-----CQYSNAVCCGDQLHCCP-EGTTCDLVNKRCIHQSNEP 258
C + TCC G C C A CC D CCP E CDL C+ N P
Sbjct: 381 CPESNTCCCLFEYGKYCFAWGCCPLEAATCCDDNYSCCPHEYPVCDLDQGTCLLSKNSP 439
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 60,156,509
Number of Sequences: 369166
Number of extensions: 1268752
Number of successful extensions: 4626
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4026
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4529
length of database: 68,354,980
effective HSP length: 102
effective length of database: 49,512,010
effective search space used: 2970720600
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)