Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_025_A16
(521 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P23785|GRN_RAT Granulins precursor [Contains: Acrogranin... 112 7e-25
sp|P28798|GRN_MOUSE Granulins precursor (Acrogranin) (Proep... 109 3e-24
sp|P28799|GRN_HUMAN Granulins precursor (Proepithelin) (PEP... 109 3e-24
sp|P28797|GRN_CAVPO Granulins precursor (Proepithelin) (PEP... 108 1e-23
sp|P80059|PMD1_LOCMI Pars intercerebralis major peptide D1 ... 64 3e-10
sp|P80930|ENA1_HORSE Antimicrobial peptide eNAP-1 59 5e-09
sp|P81013|GRN1_CYPCA Granulin-1 55 8e-08
sp|P81015|GRN3_CYPCA Granulin-3 54 2e-07
sp|P81014|GRN2_CYPCA Granulin-2 50 3e-06
sp|P25777|ORYB_ORYSA Oryzain beta chain precursor 44 3e-04
>sp|P23785|GRN_RAT Granulins precursor [Contains: Acrogranin; Granulin-1 (Granulin G);
Granulin-2 (Granulin F); Granulin-3 (Granulin B)
(Epithelin-2); Granulin-4 (Granulin A) (Epithelin-1);
Granulin-5 (Granulin C); Granulin-6 (Granulin D);
Granulin-7 (Granulin E)]
Length = 588
Score = 112 bits (279), Expect = 7e-25
Identities = 54/148 (36%), Positives = 71/148 (47%), Gaps = 2/148 (1%)
Frame = +1
Query: 4 NGKALCGDQKTCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIE 183
+ K C D TCC +G + CC NA+CC D LHCCP+ T CDL+ +CI +
Sbjct: 208 DAKTQCPDDSTCCELPTGKYGCCPMPNAICCSDHLHCCPQDTVCDLIQSKCISK------ 261
Query: 184 WPVVETIDSAKIETPKYTVERSTLREFMIKIGDKNNCPDGGQCAGLQTCCLMYTGHYGCC 363
+ + P Y V +K + +CPDG TCC + TG +GCC
Sbjct: 262 ----DYTTDLMTKLPGYPVNE-------VKCDLEVSCPDG------YTCCRLNTGAWGCC 304
Query: 364 PFSLGVCCPDLRTCCAPGYHC--VTGGC 441
PF+ VCC D CC G+ C TG C
Sbjct: 305 PFTKAVCCEDHIHCCPAGFQCHTETGTC 332
Score = 95.9 bits (237), Expect = 5e-20
Identities = 50/140 (35%), Positives = 64/140 (45%)
Frame = +1
Query: 19 CGDQKTCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVE 198
C +TCC S G CCQ +AVCC D+ HCCP G TC++ + C
Sbjct: 447 CPVGQTCCPSLKGSWACCQLPHAVCCEDRQHCCPAGYTCNVKARTC-------------- 492
Query: 199 TIDSAKIETPKYTVERSTLREFMIKIGDKNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLG 378
E +V+ S F K+G+ C G C Q+CC G + CCP+ G
Sbjct: 493 -------EKDAGSVQPSMDLTFGSKVGNV-ECGAGHFCHDNQSCCKDSQGGWACCPYVKG 544
Query: 379 VCCPDLRTCCAPGYHCVTGG 438
VCC D R CC G+HC G
Sbjct: 545 VCCRDGRHCCPIGFHCSAKG 564
Score = 95.1 bits (235), Expect = 9e-20
Identities = 47/136 (34%), Positives = 61/136 (44%)
Frame = +1
Query: 19 CGDQKTCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVE 198
C D TCC G CC A CC D++HCCP G +CDLV+ RCI + P+++
Sbjct: 132 CPDSATCCIMIDGSWGCCPMPQASCCEDRVHCCPHGASCDLVHTRCISPTG---THPLLK 188
Query: 199 TIDSAKIETPKYTVERSTLREFMIKIGDKNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLG 378
+ P R+ ++ K CPD TCC + TG YGCCP
Sbjct: 189 -------KFPAQRTNRAVASFSVVCPDAKTQCPDD------STCCELPTGKYGCCPMPNA 235
Query: 379 VCCPDLRTCCAPGYHC 426
+CC D CC C
Sbjct: 236 ICCSDHLHCCPQDTVC 251
Score = 90.9 bits (224), Expect = 2e-18
Identities = 43/140 (30%), Positives = 64/140 (45%)
Frame = +1
Query: 19 CGDQKTCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVE 198
C D TCC +G CC ++ AVCC D +HCCP G C C ++ P ++
Sbjct: 287 CPDGYTCCRLNTGAWGCCPFTKAVCCEDHIHCCPAGFQCHTETGTC---ELGVLQVPWMK 343
Query: 199 TIDSAKIETPKYTVERSTLREFMIKIGDKNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLG 378
+ +A + P + ++ + C D C TCC + +G +GCCP
Sbjct: 344 KV-TASLSLPDPQILKNDVP-----------CDDFSSCPSNNTCCRLSSGDWGCCPMPEA 391
Query: 379 VCCPDLRTCCAPGYHCVTGG 438
VCC D + CC G+ C+ G
Sbjct: 392 VCCLDHQHCCPQGFKCMDEG 411
Score = 78.6 bits (192), Expect = 9e-15
Identities = 44/136 (32%), Positives = 54/136 (39%)
Frame = +1
Query: 19 CGDQKTCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVE 198
C TCC SG CC AVCC D HCCP+G C ++ +
Sbjct: 369 CPSNNTCCRLSSGDWGCCPMPEAVCCLDHQHCCPQGFKC--------------MDEGYCQ 414
Query: 199 TIDSAKIETPKYTVERSTLREFMIKIGDKNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLG 378
D K V ++TL ++ GD C C QTCC G + CC
Sbjct: 415 KGDRMVAGLEKMPVRQTTL----LQHGDIG-CDQHTSCPVGQTCCPSLKGSWACCQLPHA 469
Query: 379 VCCPDLRTCCAPGYHC 426
VCC D + CC GY C
Sbjct: 470 VCCEDRQHCCPAGYTC 485
Score = 76.6 bits (187), Expect = 3e-14
Identities = 41/136 (30%), Positives = 51/136 (37%)
Frame = +1
Query: 19 CGDQKTCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVE 198
C D +C + SG CC +S V C D HCCP G C K C S+ +
Sbjct: 67 CPDGYSCLLTVSGTSSCCPFSEGVSCDDGQHCCPRGFHCSADGKSCSQISDSLL------ 120
Query: 199 TIDSAKIETPKYTVERSTLREFMIKIGDKNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLG 378
++ P G + CPD TCC+M G +GCCP
Sbjct: 121 ----GAVQCP----------------GSQFECPDSA------TCCIMIDGSWGCCPMPQA 154
Query: 379 VCCPDLRTCCAPGYHC 426
CC D CC G C
Sbjct: 155 SCCEDRVHCCPHGASC 170
Score = 57.0 bits (136), Expect = 3e-08
Identities = 20/49 (40%), Positives = 25/49 (51%)
Frame = +1
Query: 19 CGDQKTCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQ 165
C D ++CC GG CC Y VCC D HCCP G C +C+ +
Sbjct: 522 CHDNQSCCKDSQGGWACCPYVKGVCCRDGRHCCPIGFHCSAKGTKCLRK 570
Score = 51.6 bits (122), Expect = 1e-06
Identities = 22/52 (42%), Positives = 29/52 (55%)
Frame = +1
Query: 283 KNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHCVTGG 438
+++CPDG +C L +G CCPFS GV C D + CC G+HC G
Sbjct: 64 RDHCPDG------YSCLLTVSGTSSCCPFSEGVSCDDGQHCCPRGFHCSADG 109
>sp|P28798|GRN_MOUSE Granulins precursor (Acrogranin) (Proepithelin) (PEPI) (PC
cell-derived growth factor) (PCDGF) [Contains: Granulin
1; Granulin 2; Granulin 3; Granulin 4; Granulin 5;
Granulin 6; Granulin 7]
Length = 589
Score = 109 bits (273), Expect = 3e-24
Identities = 52/143 (36%), Positives = 72/143 (50%)
Frame = +1
Query: 4 NGKALCGDQKTCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIE 183
+ K C D TCC +G + CC NA+CC D LHCCP+ T CDL+ +C+ ++
Sbjct: 209 DAKTQCPDDSTCCELPTGKYGCCPMPNAICCSDHLHCCPQDTVCDLIQSKCLSKN----- 263
Query: 184 WPVVETIDSAKIETPKYTVERSTLREFMIKIGDKNNCPDGGQCAGLQTCCLMYTGHYGCC 363
T D + P Y V+ +K + +CP+G TCC + TG +GCC
Sbjct: 264 ----YTTD-LLTKLPGYPVKE-------VKCDMEVSCPEG------YTCCRLNTGAWGCC 305
Query: 364 PFSLGVCCPDLRTCCAPGYHCVT 432
PF+ VCC D CC G+ C T
Sbjct: 306 PFAKAVCCEDHIHCCPAGFQCHT 328
Score = 99.4 bits (246), Expect = 5e-21
Identities = 51/140 (36%), Positives = 68/140 (48%)
Frame = +1
Query: 19 CGDQKTCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVE 198
C +TCC S G CCQ +AVCC D+ HCCP G TC++ + C + + I+ PV+
Sbjct: 448 CPVGQTCCPSLKGSWACCQLPHAVCCEDRQHCCPAGYTCNVKARTC-EKDVDFIQPPVLL 506
Query: 199 TIDSAKIETPKYTVERSTLREFMIKIGDKNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLG 378
T+ K+G+ C +G C QTCC G + CCP+ G
Sbjct: 507 TLGP--------------------KVGNV-ECGEGHFCHDNQTCCKDSAGVWACCPYLKG 545
Query: 379 VCCPDLRTCCAPGYHCVTGG 438
VCC D R CC G+HC G
Sbjct: 546 VCCRDGRHCCPGGFHCSARG 565
Score = 95.5 bits (236), Expect = 7e-20
Identities = 47/137 (34%), Positives = 59/137 (43%), Gaps = 1/137 (0%)
Frame = +1
Query: 19 CGDQKTCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVE 198
C D TCC G CC A CC D++HCCP G +CDLV+ RC+ +
Sbjct: 132 CPDSATCCIMVDGSWGCCPMPQASCCEDRVHCCPHGASCDLVHTRCVSPTG--------- 182
Query: 199 TIDSAKIETPKYTVERSTLREFMIKIGD-KNNCPDGGQCAGLQTCCLMYTGHYGCCPFSL 375
+ + P R+ F + D K CPD TCC + TG YGCCP
Sbjct: 183 -THTLLKKFPAQKTNRAVSLPFSVVCPDAKTQCPDD------STCCELPTGKYGCCPMPN 235
Query: 376 GVCCPDLRTCCAPGYHC 426
+CC D CC C
Sbjct: 236 AICCSDHLHCCPQDTVC 252
Score = 91.7 bits (226), Expect = 1e-18
Identities = 43/140 (30%), Positives = 61/140 (43%)
Frame = +1
Query: 19 CGDQKTCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVE 198
C + TCC +G CC ++ AVCC D +HCCP G C H E +++
Sbjct: 288 CPEGYTCCRLNTGAWGCCPFAKAVCCEDHIHCCPAGFQC--------HTEKGTCEMGILQ 339
Query: 199 TIDSAKIETPKYTVERSTLREFMIKIGDKNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLG 378
K+ P + L+ C D +C TCC + +G +GCCP
Sbjct: 340 VPWMKKVIAPLRLPDPQILKS-------DTPCDDFTRCPTNNTCCKLNSGDWGCCPIPEA 392
Query: 379 VCCPDLRTCCAPGYHCVTGG 438
VCC D + CC G+ C+ G
Sbjct: 393 VCCSDNQHCCPQGFTCLAQG 412
Score = 83.2 bits (204), Expect = 3e-16
Identities = 42/136 (30%), Positives = 53/136 (38%)
Frame = +1
Query: 19 CGDQKTCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVE 198
C +C + SG CC +S V CGD HCCP+G C K C S+ P+
Sbjct: 67 CPAGYSCLLTVSGTSSCCPFSKGVSCGDGYHCCPQGFHCSADGKSCFQMSDNPL------ 120
Query: 199 TIDSAKIETPKYTVERSTLREFMIKIGDKNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLG 378
++ P G + CPD TCC+M G +GCCP
Sbjct: 121 ----GAVQCP----------------GSQFECPDSA------TCCIMVDGSWGCCPMPQA 154
Query: 379 VCCPDLRTCCAPGYHC 426
CC D CC G C
Sbjct: 155 SCCEDRVHCCPHGASC 170
Score = 82.8 bits (203), Expect = 5e-16
Identities = 47/137 (34%), Positives = 56/137 (40%), Gaps = 1/137 (0%)
Frame = +1
Query: 19 CGDQKTCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVE 198
C TCC SG CC AVCC D HCCP+G TC L C
Sbjct: 370 CPTNNTCCKLNSGDWGCCPIPEAVCCSDNQHCCPQGFTC-LAQGYC-------------- 414
Query: 199 TIDSAKIETPKYTVERSTLREFM-IKIGDKNNCPDGGQCAGLQTCCLMYTGHYGCCPFSL 375
K +T +E+ R+ ++IGD C C QTCC G + CC
Sbjct: 415 ----QKGDTMVAGLEKIPARQTTPLQIGDIG-CDQHTSCPVGQTCCPSLKGSWACCQLPH 469
Query: 376 GVCCPDLRTCCAPGYHC 426
VCC D + CC GY C
Sbjct: 470 AVCCEDRQHCCPAGYTC 486
Score = 55.5 bits (132), Expect = 8e-08
Identities = 20/49 (40%), Positives = 25/49 (51%)
Frame = +1
Query: 19 CGDQKTCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQ 165
C D +TCC +G CC Y VCC D HCCP G C +C+ +
Sbjct: 523 CHDNQTCCKDSAGVWACCPYLKGVCCRDGRHCCPGGFHCSARGTKCLRK 571
Score = 51.2 bits (121), Expect = 1e-06
Identities = 21/50 (42%), Positives = 25/50 (50%)
Frame = +1
Query: 289 NCPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHCVTGG 438
+C G C +C L +G CCPFS GV C D CC G+HC G
Sbjct: 60 SCQTHGHCPAGYSCLLTVSGTSSCCPFSKGVSCGDGYHCCPQGFHCSADG 109
>sp|P28799|GRN_HUMAN Granulins precursor (Proepithelin) (PEPI) [Contains: Acrogranin;
Paragranulin; Granulin-1 (Granulin G); Granulin-2
(Granulin F); Granulin-3 (Granulin B); Granulin-4
(Granulin A); Granulin-5 (Granulin C); Granulin-6
(Granulin D); Granulin-7 (Granulin E)]
Length = 593
Score = 109 bits (273), Expect = 3e-24
Identities = 51/143 (35%), Positives = 71/143 (49%)
Frame = +1
Query: 4 NGKALCGDQKTCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIE 183
+ ++ C D TCC SG + CC NA CC D LHCCP+ T CDL+ +C+ + N +
Sbjct: 210 DARSRCPDGSTCCELPSGKYGCCPMPNATCCSDHLHCCPQDTVCDLIQSKCLSKENATTD 269
Query: 184 WPVVETIDSAKIETPKYTVERSTLREFMIKIGDKNNCPDGGQCAGLQTCCLMYTGHYGCC 363
+ P +TV +K + +CPDG TCC + +G +GCC
Sbjct: 270 ---------LLTKLPAHTVGD-------VKCDMEVSCPDG------YTCCRLQSGAWGCC 307
Query: 364 PFSLGVCCPDLRTCCAPGYHCVT 432
PF+ VCC D CC G+ C T
Sbjct: 308 PFTQAVCCEDHIHCCPAGFTCDT 330
Score = 100 bits (249), Expect = 2e-21
Identities = 50/146 (34%), Positives = 64/146 (43%)
Frame = +1
Query: 19 CGDQKTCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVE 198
C D TCC +SG CC ++ AVCC D +HCCP G TCD C P + P +E
Sbjct: 290 CPDGYTCCRLQSGAWGCCPFTQAVCCEDHIHCCPAGFTCDTQKGTC---EQGPHQVPWME 346
Query: 199 TIDSAKIETPKYTVERSTLREFMIKIGDKNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLG 378
+ ++R C + C TCC + +G +GCCP
Sbjct: 347 KAPAHLSLPDPQALKRDV------------PCDNVSSCPSSDTCCQLTSGEWGCCPIPEA 394
Query: 379 VCCPDLRTCCAPGYHCVTGGCA*LGS 456
VCC D + CC GY CV G GS
Sbjct: 395 VCCSDHQHCCPQGYTCVAEGQCQRGS 420
Score = 93.6 bits (231), Expect = 3e-19
Identities = 47/141 (33%), Positives = 62/141 (43%), Gaps = 1/141 (0%)
Frame = +1
Query: 19 CGDQKTCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVE 198
C +TCC S G CCQ +AVCC D+ HCCP G TC++ + C
Sbjct: 450 CPVGQTCCPSLGGSWACCQLPHAVCCEDRQHCCPAGYTCNVKARSC-------------- 495
Query: 199 TIDSAKIETPKYTVERSTLREFMIKIGDKN-NCPDGGQCAGLQTCCLMYTGHYGCCPFSL 375
E + + +T +G K+ C +G C QTCC + CCP+
Sbjct: 496 -------EKEVVSAQPATFLARSPHVGVKDVECGEGHFCHDNQTCCRDNRQGWACCPYRQ 548
Query: 376 GVCCPDLRTCCAPGYHCVTGG 438
GVCC D R CC G+ C G
Sbjct: 549 GVCCADRRHCCPAGFRCAARG 569
Score = 93.2 bits (230), Expect = 3e-19
Identities = 49/137 (35%), Positives = 60/137 (43%), Gaps = 1/137 (0%)
Frame = +1
Query: 19 CGDQKTCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVE 198
C D TCC G CC A CC D++HCCP G CDLV+ RCI +
Sbjct: 133 CPDFSTCCVMVDGSWGCCPMPQASCCEDRVHCCPHGAFCDLVHTRCITPTG--------- 183
Query: 199 TIDSAKIETPKYTVERSTLREFMIKIGD-KNNCPDGGQCAGLQTCCLMYTGHYGCCPFSL 375
T AK + P R+ + D ++ CPDG TCC + +G YGCCP
Sbjct: 184 THPLAK-KLPAQRTNRAVALSSSVMCPDARSRCPDG------STCCELPSGKYGCCPMPN 236
Query: 376 GVCCPDLRTCCAPGYHC 426
CC D CC C
Sbjct: 237 ATCCSDHLHCCPQDTVC 253
Score = 80.1 bits (196), Expect = 3e-15
Identities = 46/136 (33%), Positives = 55/136 (40%)
Frame = +1
Query: 19 CGDQKTCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVE 198
C TCC SG CC AVCC D HCCP+G TC + +C S
Sbjct: 372 CPSSDTCCQLTSGEWGCCPIPEAVCCSDHQHCCPQGYTC-VAEGQCQRGSE--------- 421
Query: 199 TIDSAKIETPKYTVERSTLREFMIKIGDKNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLG 378
I + + P S R+ I +CP G QTCC G + CC
Sbjct: 422 -IVAGLEKMPARRASLSHPRD--IGCDQHTSCPVG------QTCCPSLGGSWACCQLPHA 472
Query: 379 VCCPDLRTCCAPGYHC 426
VCC D + CC GY C
Sbjct: 473 VCCEDRQHCCPAGYTC 488
Score = 76.6 bits (187), Expect = 3e-14
Identities = 40/139 (28%), Positives = 49/139 (35%), Gaps = 1/139 (0%)
Frame = +1
Query: 13 ALCGDQKTCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPV 192
A C +C + SG CC + AV CGD HCCP G C + C +S +
Sbjct: 65 AHCSAGHSCIFTVSGTSSCCPFPEAVACGDGHHCCPRGFHCSADGRSCFQRSGNNSVGAI 124
Query: 193 VETIDSAKIETPKYTVERSTLREFMIKIGDKNNCPDGG-QCAGLQTCCLMYTGHYGCCPF 369
CPD +C TCC+M G +GCCP
Sbjct: 125 --------------------------------QCPDSQFECPDFSTCCVMVDGSWGCCPM 152
Query: 370 SLGVCCPDLRTCCAPGYHC 426
CC D CC G C
Sbjct: 153 PQASCCEDRVHCCPHGAFC 171
Score = 57.4 bits (137), Expect = 2e-08
Identities = 20/49 (40%), Positives = 25/49 (51%)
Frame = +1
Query: 19 CGDQKTCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQ 165
C D +TCC G CC Y VCC D+ HCCP G C +C+ +
Sbjct: 527 CHDNQTCCRDNRQGWACCPYRQGVCCADRRHCCPAGFRCAARGTKCLRR 575
Score = 43.9 bits (102), Expect = 2e-04
Identities = 17/49 (34%), Positives = 21/49 (42%)
Frame = +1
Query: 292 CPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHCVTGG 438
C C+ +C +G CCPF V C D CC G+HC G
Sbjct: 61 CQVDAHCSAGHSCIFTVSGTSSCCPFPEAVACGDGHHCCPRGFHCSADG 109
>sp|P28797|GRN_CAVPO Granulins precursor (Proepithelin) (PEPI) [Contains: Acrogranin;
Granulin-1; Granulin-2; Granulin-3; Granulin-4;
Granulin-5; Granulin-6; Granulin-7]
Length = 591
Score = 108 bits (269), Expect = 1e-23
Identities = 50/143 (34%), Positives = 71/143 (49%)
Frame = +1
Query: 4 NGKALCGDQKTCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIE 183
+ ++ C D TCC SG + CC NA+CC D LHCCP+ T CDL RC+ Q+
Sbjct: 210 DSRSQCPDDTTCCLLASGEYGCCPMPNAICCSDHLHCCPQDTVCDLRQSRCLSQNK---- 265
Query: 184 WPVVETIDSAKIETPKYTVERSTLREFMIKIGDKNNCPDGGQCAGLQTCCLMYTGHYGCC 363
+ + P +TV + ++ + +CP+G QTCC + +G +GCC
Sbjct: 266 ------AKTLLTKLPSWTV-------WDVECDQEVSCPEG------QTCCRLQSGKWGCC 306
Query: 364 PFSLGVCCPDLRTCCAPGYHCVT 432
PF VCC D CC + C T
Sbjct: 307 PFPKAVCCEDHVHCCPERFRCHT 329
Score = 102 bits (255), Expect = 4e-22
Identities = 53/142 (37%), Positives = 67/142 (47%)
Frame = +1
Query: 13 ALCGDQKTCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPV 192
A C ++TCC GG CCQ +AVCC D HCCP G TC++ + C
Sbjct: 445 ASCPVRQTCCPKLGGGWACCQLPHAVCCEDGQHCCPAGYTCNVKARSC------------ 492
Query: 193 VETIDSAKIETPKYTVERSTLREFMIKIGDKNNCPDGGQCAGLQTCCLMYTGHYGCCPFS 372
+ D A + P ST + GD++ C D QTCC G + CCPF
Sbjct: 493 EKAADGAHLAAP--LAVGSTGGVMDVACGDRHFCHDE------QTCCRDSRGGWACCPFH 544
Query: 373 LGVCCPDLRTCCAPGYHCVTGG 438
GVCC D R CC G+HC + G
Sbjct: 545 QGVCCKDQRHCCPAGFHCESQG 566
Score = 95.9 bits (237), Expect = 5e-20
Identities = 52/146 (35%), Positives = 69/146 (47%), Gaps = 6/146 (4%)
Frame = +1
Query: 7 GKALCGDQKTCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQ-SNEPI- 180
G+ C D TCC G CC A CC D++HCCP G +CDLV+ RC+ + P+
Sbjct: 115 GEFECPDSSTCCHMLDGSWGCCPMPQASCCEDRVHCCPHGASCDLVHIRCVTALGSHPLT 174
Query: 181 -EWPVVETIDSAKIETPKYT--VERSTLREFMIKIGDKNNCPDG-GQCAGLQTCCLMYTG 348
+ P T + TP + + + L +I CPD QC TCCL+ +G
Sbjct: 175 TKLPAQRTNYTGAEGTPVVSPGLLPAALPTSVI-------CPDSRSQCPDDTTCCLLASG 227
Query: 349 HYGCCPFSLGVCCPDLRTCCAPGYHC 426
YGCCP +CC D CC C
Sbjct: 228 EYGCCPMPNAICCSDHLHCCPQDTVC 253
Score = 71.6 bits (174), Expect = 1e-12
Identities = 40/139 (28%), Positives = 52/139 (37%), Gaps = 1/139 (0%)
Frame = +1
Query: 13 ALCGDQKTCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPV 192
A C +C + +G CC +S A+ CGD HCCP G C CI + P
Sbjct: 51 ANCPIGHSCVLTAAGTAACCPFSQAMACGDGHHCCPYGFHCSTDGGTCIQR-------PD 103
Query: 193 VETIDSAKIETPKYTVERSTLREFMIKIGDKNNCPDGG-QCAGLQTCCLMYTGHYGCCPF 369
+ + + + CP G +C TCC M G +GCCP
Sbjct: 104 IHLLGAVQ-------------------------CPGGEFECPDSSTCCHMLDGSWGCCPM 138
Query: 370 SLGVCCPDLRTCCAPGYHC 426
CC D CC G C
Sbjct: 139 PQASCCEDRVHCCPHGASC 157
Score = 66.6 bits (161), Expect = 3e-11
Identities = 35/123 (28%), Positives = 50/123 (40%)
Frame = +1
Query: 19 CGDQKTCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVE 198
C + +TCC +SG CC + AVCC D +HCCPE C C Q + W
Sbjct: 289 CPEGQTCCRLQSGKWGCCPFPKAVCCEDHVHCCPERFRCHTEKDTC-EQGLLQVPWAQKT 347
Query: 199 TIDSAKIETPKYTVERSTLREFMIKIGDKNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLG 378
++ P + + +C + C CC + +G +GCCP S G
Sbjct: 348 PAQPSRPSQPSPPGPPGPPSP-PGPLRSEISCDEVVSCRPGNICCRLASGEWGCCPSSEG 406
Query: 379 VCC 387
C
Sbjct: 407 YLC 409
Score = 66.6 bits (161), Expect = 3e-11
Identities = 23/51 (45%), Positives = 30/51 (58%)
Frame = +1
Query: 19 CGDQKTCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSN 171
C D++TCC GG CC + VCC DQ HCCP G C+ RC+H+ +
Sbjct: 524 CHDEQTCCRDSRGGWACCPFHQGVCCKDQRHCCPAGFHCESQGTRCVHKKS 574
Score = 47.0 bits (110), Expect = 3e-05
Identities = 33/125 (26%), Positives = 50/125 (40%), Gaps = 2/125 (1%)
Frame = +1
Query: 58 GHQCCQYSNAVCCGDQLHCCP--EGTTCDLVNKRCIHQSNEPIEWPVVETIDSAKIETPK 231
G+ CC+ ++ + CCP EG C + +RC V + + K+
Sbjct: 387 GNICCRLASG-----EWGCCPSSEGYLC-MAGERC----------QVGDRLAPEKMAAHL 430
Query: 232 YTVERSTLREFMIKIGDKNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCA 411
++ ++T +G C C QTCC G + CC VCC D + CC
Sbjct: 431 MSLSQTT------DVG----CDQHASCPVRQTCCPKLGGGWACCQLPHAVCCEDGQHCCP 480
Query: 412 PGYHC 426
GY C
Sbjct: 481 AGYTC 485
Score = 46.6 bits (109), Expect = 4e-05
Identities = 21/50 (42%), Positives = 24/50 (48%)
Frame = +1
Query: 289 NCPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHCVTGG 438
NCP G +C L G CCPFS + C D CC G+HC T G
Sbjct: 52 NCPIG------HSCVLTAAGTAACCPFSQAMACGDGHHCCPYGFHCSTDG 95
>sp|P80059|PMD1_LOCMI Pars intercerebralis major peptide D1 (PMP-D1)
Length = 54
Score = 63.5 bits (153), Expect = 3e-10
Identities = 23/47 (48%), Positives = 28/47 (59%)
Frame = +1
Query: 19 CGDQKTCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCI 159
C +TCC + G CC Y VCC D +HCCP GT CD ++RCI
Sbjct: 7 CPGTETCCTTPQGEEGCCPYKEGVCCLDGIHCCPSGTVCDEDHRRCI 53
Score = 48.9 bits (115), Expect = 7e-06
Identities = 19/39 (48%), Positives = 21/39 (53%)
Frame = +1
Query: 310 CAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHC 426
C G +TCC G GCCP+ GVCC D CC G C
Sbjct: 7 CPGTETCCTTPQGEEGCCPYKEGVCCLDGIHCCPSGTVC 45
>sp|P80930|ENA1_HORSE Antimicrobial peptide eNAP-1
Length = 46
Score = 59.3 bits (142), Expect = 5e-09
Identities = 21/36 (58%), Positives = 23/36 (63%)
Frame = +1
Query: 19 CGDQKTCCASKSGGHQCCQYSNAVCCGDQLHCCPEG 126
C D +TCC + GG CC YS VCC DQ HCCP G
Sbjct: 10 CHDXQTCCRASQGGXACCPYSQGVCCADQRHCCPVG 45
Score = 53.9 bits (128), Expect = 2e-07
Identities = 21/43 (48%), Positives = 24/43 (55%)
Frame = +1
Query: 292 CPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGY 420
C +G C QTCC G CCP+S GVCC D R CC G+
Sbjct: 4 CGEGHFCHDXQTCCRASQGGXACCPYSQGVCCADQRHCCPVGF 46
>sp|P81013|GRN1_CYPCA Granulin-1
Length = 57
Score = 55.5 bits (132), Expect = 8e-08
Identities = 24/45 (53%), Positives = 26/45 (57%)
Frame = +1
Query: 292 CPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHC 426
CPDG TCCL G + CCPFS+G CC D CC GYHC
Sbjct: 10 CPDG------TTCCLSPYGVWYCCPFSMGQCCRDGIHCCRHGYHC 48
Score = 53.5 bits (127), Expect = 3e-07
Identities = 20/48 (41%), Positives = 25/48 (52%)
Frame = +1
Query: 16 LCGDQKTCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCI 159
+C D TCC S G CC +S CC D +HCC G CD + C+
Sbjct: 9 ICPDGTTCCLSPYGVWYCCPFSMGQCCRDGIHCCRHGYHCDSTSTHCL 56
>sp|P81015|GRN3_CYPCA Granulin-3
Length = 57
Score = 53.9 bits (128), Expect = 2e-07
Identities = 22/45 (48%), Positives = 24/45 (53%)
Frame = +1
Query: 292 CPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHC 426
C G C TCC G + CCPF +G CC D R CC GYHC
Sbjct: 4 CDAGITCPSGTTCCRSPFGVWYCCPFLMGQCCRDGRHCCRHGYHC 48
Score = 45.8 bits (107), Expect = 6e-05
Identities = 18/47 (38%), Positives = 21/47 (44%)
Frame = +1
Query: 19 CGDQKTCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCI 159
C TCC S G CC + CC D HCC G CD + C+
Sbjct: 10 CPSGTTCCRSPFGVWYCCPFLMGQCCRDGRHCCRHGYHCDSTSTLCL 56
>sp|P81014|GRN2_CYPCA Granulin-2
Length = 57
Score = 50.1 bits (118), Expect = 3e-06
Identities = 19/52 (36%), Positives = 24/52 (46%)
Frame = +1
Query: 4 NGKALCGDQKTCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCI 159
N + C + TCC S G CC + CC D HCC G CD + C+
Sbjct: 5 NARTTCPSRTTCCRSPFGVWYCCPFLMGQCCRDGRHCCRHGYRCDSTSTLCL 56
Score = 48.9 bits (115), Expect = 7e-06
Identities = 19/39 (48%), Positives = 21/39 (53%)
Frame = +1
Query: 310 CAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHC 426
C TCC G + CCPF +G CC D R CC GY C
Sbjct: 10 CPSRTTCCRSPFGVWYCCPFLMGQCCRDGRHCCRHGYRC 48
>sp|P25777|ORYB_ORYSA Oryzain beta chain precursor
Length = 471
Score = 43.5 bits (101), Expect = 3e-04
Identities = 19/50 (38%), Positives = 24/50 (48%), Gaps = 3/50 (6%)
Frame = +1
Query: 280 DKNNCPDGGQCA---GLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGY 420
D +CP G C G + CL++ GCCP CC D +CC P Y
Sbjct: 387 DNFSCPAGSTCCCAFGFRNLCLVW----GCCPVEGATCCKDHASCCPPDY 432
Score = 33.1 bits (74), Expect = 0.41
Identities = 17/60 (28%), Positives = 22/60 (36%), Gaps = 6/60 (10%)
Frame = +1
Query: 19 CGDQKTCCASKSGGHQC-----CQYSNAVCCGDQLHCC-PEGTTCDLVNKRCIHQSNEPI 180
C TCC + + C C A CC D CC P+ C+ C N P+
Sbjct: 391 CPAGSTCCCAFGFRNLCLVWGCCPVEGATCCKDHASCCPPDYPVCNTRAGTCSASKNSPL 450
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 63,832,569
Number of Sequences: 369166
Number of extensions: 1430722
Number of successful extensions: 5034
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4310
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4910
length of database: 68,354,980
effective HSP length: 103
effective length of database: 49,327,275
effective search space used: 3452909250
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)