Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_005_M07
(202 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P28797|GRN_CAVPO Granulins precursor (Proepithelin) (PEP... 52 4e-07
sp|P28799|GRN_HUMAN Granulins precursor (Proepithelin) (PEP... 51 1e-06
sp|P23785|GRN_RAT Granulins precursor [Contains: Acrogranin... 50 1e-06
sp|P28798|GRN_MOUSE Granulins precursor (Acrogranin) (Proep... 50 2e-06
sp|P81013|GRN1_CYPCA Granulin-1 50 2e-06
sp|P81015|GRN3_CYPCA Granulin-3 48 6e-06
sp|P81014|GRN2_CYPCA Granulin-2 45 5e-05
sp|P80930|ENA1_HORSE Antimicrobial peptide eNAP-1 44 9e-05
sp|P80059|PMD1_LOCMI Pars intercerebralis major peptide D1 ... 41 8e-04
sp|P43297|RD21A_ARATH Cysteine proteinase RD21a precursor (... 37 0.014
>sp|P28797|GRN_CAVPO Granulins precursor (Proepithelin) (PEPI) [Contains: Acrogranin;
Granulin-1; Granulin-2; Granulin-3; Granulin-4;
Granulin-5; Granulin-6; Granulin-7]
Length = 591
Score = 52.0 bits (123), Expect = 4e-07
Identities = 19/37 (51%), Positives = 22/37 (59%)
Frame = +3
Query: 3 CCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHCVTGG 113
CC G + CCPF GVCC D R CC G+HC + G
Sbjct: 530 CCRDSRGGWACCPFHQGVCCKDQRHCCPAGFHCESQG 566
Score = 45.4 bits (106), Expect = 4e-05
Identities = 16/35 (45%), Positives = 20/35 (57%)
Frame = +3
Query: 3 CCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHCVT 107
CC + +G +GCCPF VCC D CC + C T
Sbjct: 295 CCRLQSGKWGCCPFPKAVCCEDHVHCCPERFRCHT 329
Score = 43.5 bits (101), Expect = 2e-04
Identities = 15/33 (45%), Positives = 18/33 (54%)
Frame = +3
Query: 3 CCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHC 101
CCL+ +G YGCCP +CC D CC C
Sbjct: 221 CCLLASGEYGCCPMPNAICCSDHLHCCPQDTVC 253
Score = 43.1 bits (100), Expect = 2e-04
Identities = 17/37 (45%), Positives = 19/37 (51%)
Frame = +3
Query: 3 CCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHCVTGG 113
C L G CCPFS + C D CC G+HC T G
Sbjct: 59 CVLTAAGTAACCPFSQAMACGDGHHCCPYGFHCSTDG 95
Score = 40.8 bits (94), Expect = 0.001
Identities = 15/33 (45%), Positives = 16/33 (48%)
Frame = +3
Query: 3 CCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHC 101
CC M G +GCCP CC D CC G C
Sbjct: 125 CCHMLDGSWGCCPMPQASCCEDRVHCCPHGASC 157
Score = 38.5 bits (88), Expect = 0.005
Identities = 14/33 (42%), Positives = 16/33 (48%)
Frame = +3
Query: 3 CCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHC 101
CC G + CC VCC D + CC GY C
Sbjct: 453 CCPKLGGGWACCQLPHAVCCEDGQHCCPAGYTC 485
Score = 30.8 bits (68), Expect = 1.0
Identities = 10/20 (50%), Positives = 13/20 (65%)
Frame = +3
Query: 3 CCLMYTGHYGCCPFSLGVCC 62
CC + +G +GCCP S G C
Sbjct: 390 CCRLASGEWGCCPSSEGYLC 409
>sp|P28799|GRN_HUMAN Granulins precursor (Proepithelin) (PEPI) [Contains: Acrogranin;
Paragranulin; Granulin-1 (Granulin G); Granulin-2
(Granulin F); Granulin-3 (Granulin B); Granulin-4
(Granulin A); Granulin-5 (Granulin C); Granulin-6
(Granulin D); Granulin-7 (Granulin E)]
Length = 593
Score = 50.8 bits (120), Expect = 1e-06
Identities = 20/43 (46%), Positives = 24/43 (55%)
Frame = +3
Query: 3 CCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHCVTGGCA*LGS 131
CC + +G +GCCP VCC D + CC GY CV G GS
Sbjct: 378 CCQLTSGEWGCCPIPEAVCCSDHQHCCPQGYTCVAEGQCQRGS 420
Score = 48.1 bits (113), Expect = 6e-06
Identities = 17/35 (48%), Positives = 22/35 (62%)
Frame = +3
Query: 3 CCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHCVT 107
CC + +G +GCCPF+ VCC D CC G+ C T
Sbjct: 296 CCRLQSGAWGCCPFTQAVCCEDHIHCCPAGFTCDT 330
Score = 45.1 bits (105), Expect = 5e-05
Identities = 16/37 (43%), Positives = 19/37 (51%)
Frame = +3
Query: 3 CCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHCVTGG 113
CC + CCP+ GVCC D R CC G+ C G
Sbjct: 533 CCRDNRQGWACCPYRQGVCCADRRHCCPAGFRCAARG 569
Score = 42.4 bits (98), Expect = 3e-04
Identities = 15/33 (45%), Positives = 17/33 (51%)
Frame = +3
Query: 3 CCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHC 101
CC+M G +GCCP CC D CC G C
Sbjct: 139 CCVMVDGSWGCCPMPQASCCEDRVHCCPHGAFC 171
Score = 39.7 bits (91), Expect = 0.002
Identities = 15/37 (40%), Positives = 17/37 (45%)
Frame = +3
Query: 3 CCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHCVTGG 113
C +G CCPF V C D CC G+HC G
Sbjct: 73 CIFTVSGTSSCCPFPEAVACGDGHHCCPRGFHCSADG 109
Score = 39.7 bits (91), Expect = 0.002
Identities = 14/33 (42%), Positives = 16/33 (48%)
Frame = +3
Query: 3 CCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHC 101
CC G + CC VCC D + CC GY C
Sbjct: 456 CCPSLGGSWACCQLPHAVCCEDRQHCCPAGYTC 488
Score = 38.9 bits (89), Expect = 0.004
Identities = 14/33 (42%), Positives = 16/33 (48%)
Frame = +3
Query: 3 CCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHC 101
CC + +G YGCCP CC D CC C
Sbjct: 221 CCELPSGKYGCCPMPNATCCSDHLHCCPQDTVC 253
>sp|P23785|GRN_RAT Granulins precursor [Contains: Acrogranin; Granulin-1 (Granulin G);
Granulin-2 (Granulin F); Granulin-3 (Granulin B)
(Epithelin-2); Granulin-4 (Granulin A) (Epithelin-1);
Granulin-5 (Granulin C); Granulin-6 (Granulin D);
Granulin-7 (Granulin E)]
Length = 588
Score = 50.4 bits (119), Expect = 1e-06
Identities = 20/40 (50%), Positives = 24/40 (60%), Gaps = 2/40 (5%)
Frame = +3
Query: 3 CCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHC--VTGGC 116
CC + TG +GCCPF+ VCC D CC G+ C TG C
Sbjct: 293 CCRLNTGAWGCCPFTKAVCCEDHIHCCPAGFQCHTETGTC 332
Score = 48.1 bits (113), Expect = 6e-06
Identities = 18/37 (48%), Positives = 21/37 (56%)
Frame = +3
Query: 3 CCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHCVTGG 113
CC G + CCP+ GVCC D R CC G+HC G
Sbjct: 528 CCKDSQGGWACCPYVKGVCCRDGRHCCPIGFHCSAKG 564
Score = 46.6 bits (109), Expect = 2e-05
Identities = 16/37 (43%), Positives = 22/37 (59%)
Frame = +3
Query: 3 CCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHCVTGG 113
CC + +G +GCCP VCC D + CC G+ C+ G
Sbjct: 375 CCRLSSGDWGCCPMPEAVCCLDHQHCCPQGFKCMDEG 411
Score = 45.8 bits (107), Expect = 3e-05
Identities = 18/37 (48%), Positives = 21/37 (56%)
Frame = +3
Query: 3 CCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHCVTGG 113
C L +G CCPFS GV C D + CC G+HC G
Sbjct: 73 CLLTVSGTSSCCPFSEGVSCDDGQHCCPRGFHCSADG 109
Score = 42.7 bits (99), Expect = 3e-04
Identities = 15/33 (45%), Positives = 17/33 (51%)
Frame = +3
Query: 3 CCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHC 101
CC+M G +GCCP CC D CC G C
Sbjct: 138 CCIMIDGSWGCCPMPQASCCEDRVHCCPHGASC 170
Score = 41.6 bits (96), Expect = 6e-04
Identities = 15/33 (45%), Positives = 17/33 (51%)
Frame = +3
Query: 3 CCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHC 101
CC + TG YGCCP +CC D CC C
Sbjct: 219 CCELPTGKYGCCPMPNAICCSDHLHCCPQDTVC 251
Score = 40.0 bits (92), Expect = 0.002
Identities = 14/33 (42%), Positives = 16/33 (48%)
Frame = +3
Query: 3 CCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHC 101
CC G + CC VCC D + CC GY C
Sbjct: 453 CCPSLKGSWACCQLPHAVCCEDRQHCCPAGYTC 485
>sp|P28798|GRN_MOUSE Granulins precursor (Acrogranin) (Proepithelin) (PEPI) (PC
cell-derived growth factor) (PCDGF) [Contains: Granulin
1; Granulin 2; Granulin 3; Granulin 4; Granulin 5;
Granulin 6; Granulin 7]
Length = 589
Score = 50.1 bits (118), Expect = 2e-06
Identities = 18/35 (51%), Positives = 22/35 (62%)
Frame = +3
Query: 3 CCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHCVT 107
CC + TG +GCCPF+ VCC D CC G+ C T
Sbjct: 294 CCRLNTGAWGCCPFAKAVCCEDHIHCCPAGFQCHT 328
Score = 48.5 bits (114), Expect = 5e-06
Identities = 18/37 (48%), Positives = 21/37 (56%)
Frame = +3
Query: 3 CCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHCVTGG 113
CC G + CCP+ GVCC D R CC G+HC G
Sbjct: 529 CCKDSAGVWACCPYLKGVCCRDGRHCCPGGFHCSARG 565
Score = 47.4 bits (111), Expect = 1e-05
Identities = 16/37 (43%), Positives = 22/37 (59%)
Frame = +3
Query: 3 CCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHCVTGG 113
CC + +G +GCCP VCC D + CC G+ C+ G
Sbjct: 376 CCKLNSGDWGCCPIPEAVCCSDNQHCCPQGFTCLAQG 412
Score = 45.1 bits (105), Expect = 5e-05
Identities = 18/37 (48%), Positives = 20/37 (54%)
Frame = +3
Query: 3 CCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHCVTGG 113
C L +G CCPFS GV C D CC G+HC G
Sbjct: 73 CLLTVSGTSSCCPFSKGVSCGDGYHCCPQGFHCSADG 109
Score = 42.7 bits (99), Expect = 3e-04
Identities = 15/33 (45%), Positives = 17/33 (51%)
Frame = +3
Query: 3 CCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHC 101
CC+M G +GCCP CC D CC G C
Sbjct: 138 CCIMVDGSWGCCPMPQASCCEDRVHCCPHGASC 170
Score = 41.6 bits (96), Expect = 6e-04
Identities = 15/33 (45%), Positives = 17/33 (51%)
Frame = +3
Query: 3 CCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHC 101
CC + TG YGCCP +CC D CC C
Sbjct: 220 CCELPTGKYGCCPMPNAICCSDHLHCCPQDTVC 252
Score = 40.0 bits (92), Expect = 0.002
Identities = 14/33 (42%), Positives = 16/33 (48%)
Frame = +3
Query: 3 CCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHC 101
CC G + CC VCC D + CC GY C
Sbjct: 454 CCPSLKGSWACCQLPHAVCCEDRQHCCPAGYTC 486
>sp|P81013|GRN1_CYPCA Granulin-1
Length = 57
Score = 49.7 bits (117), Expect = 2e-06
Identities = 19/33 (57%), Positives = 21/33 (63%)
Frame = +3
Query: 3 CCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHC 101
CCL G + CCPFS+G CC D CC GYHC
Sbjct: 16 CCLSPYGVWYCCPFSMGQCCRDGIHCCRHGYHC 48
>sp|P81015|GRN3_CYPCA Granulin-3
Length = 57
Score = 48.1 bits (113), Expect = 6e-06
Identities = 18/33 (54%), Positives = 20/33 (60%)
Frame = +3
Query: 3 CCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHC 101
CC G + CCPF +G CC D R CC GYHC
Sbjct: 16 CCRSPFGVWYCCPFLMGQCCRDGRHCCRHGYHC 48
>sp|P81014|GRN2_CYPCA Granulin-2
Length = 57
Score = 45.1 bits (105), Expect = 5e-05
Identities = 17/33 (51%), Positives = 19/33 (57%)
Frame = +3
Query: 3 CCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHC 101
CC G + CCPF +G CC D R CC GY C
Sbjct: 16 CCRSPFGVWYCCPFLMGQCCRDGRHCCRHGYRC 48
>sp|P80930|ENA1_HORSE Antimicrobial peptide eNAP-1
Length = 46
Score = 44.3 bits (103), Expect = 9e-05
Identities = 16/31 (51%), Positives = 18/31 (58%)
Frame = +3
Query: 3 CCLMYTGHYGCCPFSLGVCCPDLRTCCAPGY 95
CC G CCP+S GVCC D R CC G+
Sbjct: 16 CCRASQGGXACCPYSQGVCCADQRHCCPVGF 46
>sp|P80059|PMD1_LOCMI Pars intercerebralis major peptide D1 (PMP-D1)
Length = 54
Score = 41.2 bits (95), Expect = 8e-04
Identities = 16/33 (48%), Positives = 17/33 (51%)
Frame = +3
Query: 3 CCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHC 101
CC G GCCP+ GVCC D CC G C
Sbjct: 13 CCTTPQGEEGCCPYKEGVCCLDGIHCCPSGTVC 45
>sp|P43297|RD21A_ARATH Cysteine proteinase RD21a precursor (RD21)
Length = 462
Score = 37.0 bits (84), Expect = 0.014
Identities = 15/35 (42%), Positives = 16/35 (45%), Gaps = 4/35 (11%)
Frame = +3
Query: 3 CCLMYTGHY----GCCPFSLGVCCPDLRTCCAPGY 95
CCL G Y GCCP CC D +CC Y
Sbjct: 388 CCLFEYGKYCFAWGCCPLEAATCCDDNYSCCPHEY 422
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 24,968,515
Number of Sequences: 369166
Number of extensions: 444930
Number of successful extensions: 1343
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 1231
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 1340
length of database: 68,354,980
effective HSP length: 38
effective length of database: 61,335,050
effective search space used: 1717381400
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)