Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_014_M16
(511 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P23785|GRN_RAT Granulins precursor [Contains: Acrogranin... 110 2e-24
sp|P28799|GRN_HUMAN Granulins precursor (Proepithelin) (PEP... 108 6e-24
sp|P28798|GRN_MOUSE Granulins precursor (Acrogranin) (Proep... 108 1e-23
sp|P28797|GRN_CAVPO Granulins precursor (Proepithelin) (PEP... 107 2e-23
sp|P80059|PMD1_LOCMI Pars intercerebralis major peptide D1 ... 64 3e-10
sp|P80930|ENA1_HORSE Antimicrobial peptide eNAP-1 59 5e-09
sp|P81013|GRN1_CYPCA Granulin-1 55 7e-08
sp|P81015|GRN3_CYPCA Granulin-3 54 2e-07
sp|P81014|GRN2_CYPCA Granulin-2 49 7e-06
sp|P25777|ORYB_ORYSA Oryzain beta chain precursor 44 3e-04
>sp|P23785|GRN_RAT Granulins precursor [Contains: Acrogranin; Granulin-1 (Granulin G);
Granulin-2 (Granulin F); Granulin-3 (Granulin B)
(Epithelin-2); Granulin-4 (Granulin A) (Epithelin-1);
Granulin-5 (Granulin C); Granulin-6 (Granulin D);
Granulin-7 (Granulin E)]
Length = 588
Score = 110 bits (275), Expect = 2e-24
Identities = 53/143 (37%), Positives = 69/143 (48%), Gaps = 2/143 (1%)
Frame = +3
Query: 3 CGDQKTCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVE 182
C D TCC +G + CC NA+CC D LHCCP+ T CDL+ +CI + +
Sbjct: 213 CPDDSTCCELPTGKYGCCPMPNAICCSDHLHCCPQDTVCDLIQSKCISK----------D 262
Query: 183 TIDSAKIETPKYTVERSTLREFMIKIGDKNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLG 362
+ P Y V +K + +CPDG TCC + TG +GCCPF+
Sbjct: 263 YTTDLMTKLPGYPVNE-------VKCDLEVSCPDG------YTCCRLNTGAWGCCPFTKA 309
Query: 363 VCCPDLRTCCAPGYHC--VTGGC 425
VCC D CC G+ C TG C
Sbjct: 310 VCCEDHIHCCPAGFQCHTETGTC 332
Score = 95.9 bits (237), Expect = 5e-20
Identities = 50/140 (35%), Positives = 64/140 (45%)
Frame = +3
Query: 3 CGDQKTCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVE 182
C +TCC S G CCQ +AVCC D+ HCCP G TC++ + C
Sbjct: 447 CPVGQTCCPSLKGSWACCQLPHAVCCEDRQHCCPAGYTCNVKARTC-------------- 492
Query: 183 TIDSAKIETPKYTVERSTLREFMIKIGDKNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLG 362
E +V+ S F K+G+ C G C Q+CC G + CCP+ G
Sbjct: 493 -------EKDAGSVQPSMDLTFGSKVGNV-ECGAGHFCHDNQSCCKDSQGGWACCPYVKG 544
Query: 363 VCCPDLRTCCAPGYHCVTGG 422
VCC D R CC G+HC G
Sbjct: 545 VCCRDGRHCCPIGFHCSAKG 564
Score = 95.1 bits (235), Expect = 8e-20
Identities = 47/136 (34%), Positives = 61/136 (44%)
Frame = +3
Query: 3 CGDQKTCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVE 182
C D TCC G CC A CC D++HCCP G +CDLV+ RCI + P+++
Sbjct: 132 CPDSATCCIMIDGSWGCCPMPQASCCEDRVHCCPHGASCDLVHTRCISPTG---THPLLK 188
Query: 183 TIDSAKIETPKYTVERSTLREFMIKIGDKNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLG 362
+ P R+ ++ K CPD TCC + TG YGCCP
Sbjct: 189 -------KFPAQRTNRAVASFSVVCPDAKTQCPDD------STCCELPTGKYGCCPMPNA 235
Query: 363 VCCPDLRTCCAPGYHC 410
+CC D CC C
Sbjct: 236 ICCSDHLHCCPQDTVC 251
Score = 90.9 bits (224), Expect = 2e-18
Identities = 43/140 (30%), Positives = 64/140 (45%)
Frame = +3
Query: 3 CGDQKTCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVE 182
C D TCC +G CC ++ AVCC D +HCCP G C C ++ P ++
Sbjct: 287 CPDGYTCCRLNTGAWGCCPFTKAVCCEDHIHCCPAGFQCHTETGTC---ELGVLQVPWMK 343
Query: 183 TIDSAKIETPKYTVERSTLREFMIKIGDKNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLG 362
+ +A + P + ++ + C D C TCC + +G +GCCP
Sbjct: 344 KV-TASLSLPDPQILKNDVP-----------CDDFSSCPSNNTCCRLSSGDWGCCPMPEA 391
Query: 363 VCCPDLRTCCAPGYHCVTGG 422
VCC D + CC G+ C+ G
Sbjct: 392 VCCLDHQHCCPQGFKCMDEG 411
Score = 78.6 bits (192), Expect = 8e-15
Identities = 44/136 (32%), Positives = 54/136 (39%)
Frame = +3
Query: 3 CGDQKTCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVE 182
C TCC SG CC AVCC D HCCP+G C ++ +
Sbjct: 369 CPSNNTCCRLSSGDWGCCPMPEAVCCLDHQHCCPQGFKC--------------MDEGYCQ 414
Query: 183 TIDSAKIETPKYTVERSTLREFMIKIGDKNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLG 362
D K V ++TL ++ GD C C QTCC G + CC
Sbjct: 415 KGDRMVAGLEKMPVRQTTL----LQHGDIG-CDQHTSCPVGQTCCPSLKGSWACCQLPHA 469
Query: 363 VCCPDLRTCCAPGYHC 410
VCC D + CC GY C
Sbjct: 470 VCCEDRQHCCPAGYTC 485
Score = 76.6 bits (187), Expect = 3e-14
Identities = 41/136 (30%), Positives = 51/136 (37%)
Frame = +3
Query: 3 CGDQKTCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVE 182
C D +C + SG CC +S V C D HCCP G C K C S+ +
Sbjct: 67 CPDGYSCLLTVSGTSSCCPFSEGVSCDDGQHCCPRGFHCSADGKSCSQISDSLL------ 120
Query: 183 TIDSAKIETPKYTVERSTLREFMIKIGDKNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLG 362
++ P G + CPD TCC+M G +GCCP
Sbjct: 121 ----GAVQCP----------------GSQFECPDSA------TCCIMIDGSWGCCPMPQA 154
Query: 363 VCCPDLRTCCAPGYHC 410
CC D CC G C
Sbjct: 155 SCCEDRVHCCPHGASC 170
Score = 57.0 bits (136), Expect = 3e-08
Identities = 20/49 (40%), Positives = 25/49 (51%)
Frame = +3
Query: 3 CGDQKTCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQ 149
C D ++CC GG CC Y VCC D HCCP G C +C+ +
Sbjct: 522 CHDNQSCCKDSQGGWACCPYVKGVCCRDGRHCCPIGFHCSAKGTKCLRK 570
Score = 51.6 bits (122), Expect = 1e-06
Identities = 22/52 (42%), Positives = 29/52 (55%)
Frame = +3
Query: 267 KNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHCVTGG 422
+++CPDG +C L +G CCPFS GV C D + CC G+HC G
Sbjct: 64 RDHCPDG------YSCLLTVSGTSSCCPFSEGVSCDDGQHCCPRGFHCSADG 109
>sp|P28799|GRN_HUMAN Granulins precursor (Proepithelin) (PEPI) [Contains: Acrogranin;
Paragranulin; Granulin-1 (Granulin G); Granulin-2
(Granulin F); Granulin-3 (Granulin B); Granulin-4
(Granulin A); Granulin-5 (Granulin C); Granulin-6
(Granulin D); Granulin-7 (Granulin E)]
Length = 593
Score = 108 bits (271), Expect = 6e-24
Identities = 51/138 (36%), Positives = 68/138 (49%)
Frame = +3
Query: 3 CGDQKTCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVE 182
C D TCC SG + CC NA CC D LHCCP+ T CDL+ +C+ + N +
Sbjct: 215 CPDGSTCCELPSGKYGCCPMPNATCCSDHLHCCPQDTVCDLIQSKCLSKENATTD----- 269
Query: 183 TIDSAKIETPKYTVERSTLREFMIKIGDKNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLG 362
+ P +TV +K + +CPDG TCC + +G +GCCPF+
Sbjct: 270 ----LLTKLPAHTVGD-------VKCDMEVSCPDG------YTCCRLQSGAWGCCPFTQA 312
Query: 363 VCCPDLRTCCAPGYHCVT 416
VCC D CC G+ C T
Sbjct: 313 VCCEDHIHCCPAGFTCDT 330
Score = 100 bits (249), Expect = 2e-21
Identities = 50/146 (34%), Positives = 64/146 (43%)
Frame = +3
Query: 3 CGDQKTCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVE 182
C D TCC +SG CC ++ AVCC D +HCCP G TCD C P + P +E
Sbjct: 290 CPDGYTCCRLQSGAWGCCPFTQAVCCEDHIHCCPAGFTCDTQKGTC---EQGPHQVPWME 346
Query: 183 TIDSAKIETPKYTVERSTLREFMIKIGDKNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLG 362
+ ++R C + C TCC + +G +GCCP
Sbjct: 347 KAPAHLSLPDPQALKRDV------------PCDNVSSCPSSDTCCQLTSGEWGCCPIPEA 394
Query: 363 VCCPDLRTCCAPGYHCVTGGCA*LGS 440
VCC D + CC GY CV G GS
Sbjct: 395 VCCSDHQHCCPQGYTCVAEGQCQRGS 420
Score = 93.6 bits (231), Expect = 2e-19
Identities = 47/141 (33%), Positives = 62/141 (43%), Gaps = 1/141 (0%)
Frame = +3
Query: 3 CGDQKTCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVE 182
C +TCC S G CCQ +AVCC D+ HCCP G TC++ + C
Sbjct: 450 CPVGQTCCPSLGGSWACCQLPHAVCCEDRQHCCPAGYTCNVKARSC-------------- 495
Query: 183 TIDSAKIETPKYTVERSTLREFMIKIGDKN-NCPDGGQCAGLQTCCLMYTGHYGCCPFSL 359
E + + +T +G K+ C +G C QTCC + CCP+
Sbjct: 496 -------EKEVVSAQPATFLARSPHVGVKDVECGEGHFCHDNQTCCRDNRQGWACCPYRQ 548
Query: 360 GVCCPDLRTCCAPGYHCVTGG 422
GVCC D R CC G+ C G
Sbjct: 549 GVCCADRRHCCPAGFRCAARG 569
Score = 93.2 bits (230), Expect = 3e-19
Identities = 49/137 (35%), Positives = 60/137 (43%), Gaps = 1/137 (0%)
Frame = +3
Query: 3 CGDQKTCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVE 182
C D TCC G CC A CC D++HCCP G CDLV+ RCI +
Sbjct: 133 CPDFSTCCVMVDGSWGCCPMPQASCCEDRVHCCPHGAFCDLVHTRCITPTG--------- 183
Query: 183 TIDSAKIETPKYTVERSTLREFMIKIGD-KNNCPDGGQCAGLQTCCLMYTGHYGCCPFSL 359
T AK + P R+ + D ++ CPDG TCC + +G YGCCP
Sbjct: 184 THPLAK-KLPAQRTNRAVALSSSVMCPDARSRCPDG------STCCELPSGKYGCCPMPN 236
Query: 360 GVCCPDLRTCCAPGYHC 410
CC D CC C
Sbjct: 237 ATCCSDHLHCCPQDTVC 253
Score = 80.1 bits (196), Expect = 3e-15
Identities = 46/136 (33%), Positives = 55/136 (40%)
Frame = +3
Query: 3 CGDQKTCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVE 182
C TCC SG CC AVCC D HCCP+G TC + +C S
Sbjct: 372 CPSSDTCCQLTSGEWGCCPIPEAVCCSDHQHCCPQGYTC-VAEGQCQRGSE--------- 421
Query: 183 TIDSAKIETPKYTVERSTLREFMIKIGDKNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLG 362
I + + P S R+ I +CP G QTCC G + CC
Sbjct: 422 -IVAGLEKMPARRASLSHPRD--IGCDQHTSCPVG------QTCCPSLGGSWACCQLPHA 472
Query: 363 VCCPDLRTCCAPGYHC 410
VCC D + CC GY C
Sbjct: 473 VCCEDRQHCCPAGYTC 488
Score = 76.3 bits (186), Expect = 4e-14
Identities = 39/137 (28%), Positives = 48/137 (35%), Gaps = 1/137 (0%)
Frame = +3
Query: 3 CGDQKTCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVE 182
C +C + SG CC + AV CGD HCCP G C + C +S +
Sbjct: 67 CSAGHSCIFTVSGTSSCCPFPEAVACGDGHHCCPRGFHCSADGRSCFQRSGNNSVGAI-- 124
Query: 183 TIDSAKIETPKYTVERSTLREFMIKIGDKNNCPDGG-QCAGLQTCCLMYTGHYGCCPFSL 359
CPD +C TCC+M G +GCCP
Sbjct: 125 ------------------------------QCPDSQFECPDFSTCCVMVDGSWGCCPMPQ 154
Query: 360 GVCCPDLRTCCAPGYHC 410
CC D CC G C
Sbjct: 155 ASCCEDRVHCCPHGAFC 171
Score = 57.4 bits (137), Expect = 2e-08
Identities = 20/49 (40%), Positives = 25/49 (51%)
Frame = +3
Query: 3 CGDQKTCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQ 149
C D +TCC G CC Y VCC D+ HCCP G C +C+ +
Sbjct: 527 CHDNQTCCRDNRQGWACCPYRQGVCCADRRHCCPAGFRCAARGTKCLRR 575
Score = 43.9 bits (102), Expect = 2e-04
Identities = 17/49 (34%), Positives = 21/49 (42%)
Frame = +3
Query: 276 CPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHCVTGG 422
C C+ +C +G CCPF V C D CC G+HC G
Sbjct: 61 CQVDAHCSAGHSCIFTVSGTSSCCPFPEAVACGDGHHCCPRGFHCSADG 109
>sp|P28798|GRN_MOUSE Granulins precursor (Acrogranin) (Proepithelin) (PEPI) (PC
cell-derived growth factor) (PCDGF) [Contains: Granulin
1; Granulin 2; Granulin 3; Granulin 4; Granulin 5;
Granulin 6; Granulin 7]
Length = 589
Score = 108 bits (269), Expect = 1e-23
Identities = 51/138 (36%), Positives = 70/138 (50%)
Frame = +3
Query: 3 CGDQKTCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVE 182
C D TCC +G + CC NA+CC D LHCCP+ T CDL+ +C+ ++
Sbjct: 214 CPDDSTCCELPTGKYGCCPMPNAICCSDHLHCCPQDTVCDLIQSKCLSKN---------Y 264
Query: 183 TIDSAKIETPKYTVERSTLREFMIKIGDKNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLG 362
T D + P Y V+ +K + +CP+G TCC + TG +GCCPF+
Sbjct: 265 TTD-LLTKLPGYPVKE-------VKCDMEVSCPEG------YTCCRLNTGAWGCCPFAKA 310
Query: 363 VCCPDLRTCCAPGYHCVT 416
VCC D CC G+ C T
Sbjct: 311 VCCEDHIHCCPAGFQCHT 328
Score = 99.4 bits (246), Expect = 4e-21
Identities = 51/140 (36%), Positives = 68/140 (48%)
Frame = +3
Query: 3 CGDQKTCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVE 182
C +TCC S G CCQ +AVCC D+ HCCP G TC++ + C + + I+ PV+
Sbjct: 448 CPVGQTCCPSLKGSWACCQLPHAVCCEDRQHCCPAGYTCNVKARTC-EKDVDFIQPPVLL 506
Query: 183 TIDSAKIETPKYTVERSTLREFMIKIGDKNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLG 362
T+ K+G+ C +G C QTCC G + CCP+ G
Sbjct: 507 TLGP--------------------KVGNV-ECGEGHFCHDNQTCCKDSAGVWACCPYLKG 545
Query: 363 VCCPDLRTCCAPGYHCVTGG 422
VCC D R CC G+HC G
Sbjct: 546 VCCRDGRHCCPGGFHCSARG 565
Score = 95.5 bits (236), Expect = 6e-20
Identities = 47/137 (34%), Positives = 59/137 (43%), Gaps = 1/137 (0%)
Frame = +3
Query: 3 CGDQKTCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVE 182
C D TCC G CC A CC D++HCCP G +CDLV+ RC+ +
Sbjct: 132 CPDSATCCIMVDGSWGCCPMPQASCCEDRVHCCPHGASCDLVHTRCVSPTG--------- 182
Query: 183 TIDSAKIETPKYTVERSTLREFMIKIGD-KNNCPDGGQCAGLQTCCLMYTGHYGCCPFSL 359
+ + P R+ F + D K CPD TCC + TG YGCCP
Sbjct: 183 -THTLLKKFPAQKTNRAVSLPFSVVCPDAKTQCPDD------STCCELPTGKYGCCPMPN 235
Query: 360 GVCCPDLRTCCAPGYHC 410
+CC D CC C
Sbjct: 236 AICCSDHLHCCPQDTVC 252
Score = 91.7 bits (226), Expect = 9e-19
Identities = 43/140 (30%), Positives = 61/140 (43%)
Frame = +3
Query: 3 CGDQKTCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVE 182
C + TCC +G CC ++ AVCC D +HCCP G C H E +++
Sbjct: 288 CPEGYTCCRLNTGAWGCCPFAKAVCCEDHIHCCPAGFQC--------HTEKGTCEMGILQ 339
Query: 183 TIDSAKIETPKYTVERSTLREFMIKIGDKNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLG 362
K+ P + L+ C D +C TCC + +G +GCCP
Sbjct: 340 VPWMKKVIAPLRLPDPQILKS-------DTPCDDFTRCPTNNTCCKLNSGDWGCCPIPEA 392
Query: 363 VCCPDLRTCCAPGYHCVTGG 422
VCC D + CC G+ C+ G
Sbjct: 393 VCCSDNQHCCPQGFTCLAQG 412
Score = 83.2 bits (204), Expect = 3e-16
Identities = 42/136 (30%), Positives = 53/136 (38%)
Frame = +3
Query: 3 CGDQKTCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVE 182
C +C + SG CC +S V CGD HCCP+G C K C S+ P+
Sbjct: 67 CPAGYSCLLTVSGTSSCCPFSKGVSCGDGYHCCPQGFHCSADGKSCFQMSDNPL------ 120
Query: 183 TIDSAKIETPKYTVERSTLREFMIKIGDKNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLG 362
++ P G + CPD TCC+M G +GCCP
Sbjct: 121 ----GAVQCP----------------GSQFECPDSA------TCCIMVDGSWGCCPMPQA 154
Query: 363 VCCPDLRTCCAPGYHC 410
CC D CC G C
Sbjct: 155 SCCEDRVHCCPHGASC 170
Score = 82.8 bits (203), Expect = 4e-16
Identities = 47/137 (34%), Positives = 56/137 (40%), Gaps = 1/137 (0%)
Frame = +3
Query: 3 CGDQKTCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVE 182
C TCC SG CC AVCC D HCCP+G TC L C
Sbjct: 370 CPTNNTCCKLNSGDWGCCPIPEAVCCSDNQHCCPQGFTC-LAQGYC-------------- 414
Query: 183 TIDSAKIETPKYTVERSTLREFM-IKIGDKNNCPDGGQCAGLQTCCLMYTGHYGCCPFSL 359
K +T +E+ R+ ++IGD C C QTCC G + CC
Sbjct: 415 ----QKGDTMVAGLEKIPARQTTPLQIGDIG-CDQHTSCPVGQTCCPSLKGSWACCQLPH 469
Query: 360 GVCCPDLRTCCAPGYHC 410
VCC D + CC GY C
Sbjct: 470 AVCCEDRQHCCPAGYTC 486
Score = 55.5 bits (132), Expect = 7e-08
Identities = 20/49 (40%), Positives = 25/49 (51%)
Frame = +3
Query: 3 CGDQKTCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQ 149
C D +TCC +G CC Y VCC D HCCP G C +C+ +
Sbjct: 523 CHDNQTCCKDSAGVWACCPYLKGVCCRDGRHCCPGGFHCSARGTKCLRK 571
Score = 51.2 bits (121), Expect = 1e-06
Identities = 21/50 (42%), Positives = 25/50 (50%)
Frame = +3
Query: 273 NCPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHCVTGG 422
+C G C +C L +G CCPFS GV C D CC G+HC G
Sbjct: 60 SCQTHGHCPAGYSCLLTVSGTSSCCPFSKGVSCGDGYHCCPQGFHCSADG 109
>sp|P28797|GRN_CAVPO Granulins precursor (Proepithelin) (PEPI) [Contains: Acrogranin;
Granulin-1; Granulin-2; Granulin-3; Granulin-4;
Granulin-5; Granulin-6; Granulin-7]
Length = 591
Score = 107 bits (267), Expect = 2e-23
Identities = 50/138 (36%), Positives = 68/138 (49%)
Frame = +3
Query: 3 CGDQKTCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVE 182
C D TCC SG + CC NA+CC D LHCCP+ T CDL RC+ Q+
Sbjct: 215 CPDDTTCCLLASGEYGCCPMPNAICCSDHLHCCPQDTVCDLRQSRCLSQNK--------- 265
Query: 183 TIDSAKIETPKYTVERSTLREFMIKIGDKNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLG 362
+ + P +TV + ++ + +CP+G QTCC + +G +GCCPF
Sbjct: 266 -AKTLLTKLPSWTV-------WDVECDQEVSCPEG------QTCCRLQSGKWGCCPFPKA 311
Query: 363 VCCPDLRTCCAPGYHCVT 416
VCC D CC + C T
Sbjct: 312 VCCEDHVHCCPERFRCHT 329
Score = 102 bits (253), Expect = 7e-22
Identities = 52/140 (37%), Positives = 66/140 (47%)
Frame = +3
Query: 3 CGDQKTCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVE 182
C ++TCC GG CCQ +AVCC D HCCP G TC++ + C +
Sbjct: 447 CPVRQTCCPKLGGGWACCQLPHAVCCEDGQHCCPAGYTCNVKARSC------------EK 494
Query: 183 TIDSAKIETPKYTVERSTLREFMIKIGDKNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLG 362
D A + P ST + GD++ C D QTCC G + CCPF G
Sbjct: 495 AADGAHLAAP--LAVGSTGGVMDVACGDRHFCHDE------QTCCRDSRGGWACCPFHQG 546
Query: 363 VCCPDLRTCCAPGYHCVTGG 422
VCC D R CC G+HC + G
Sbjct: 547 VCCKDQRHCCPAGFHCESQG 566
Score = 95.1 bits (235), Expect = 8e-20
Identities = 51/142 (35%), Positives = 67/142 (47%), Gaps = 6/142 (4%)
Frame = +3
Query: 3 CGDQKTCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQ-SNEPI--EWP 173
C D TCC G CC A CC D++HCCP G +CDLV+ RC+ + P+ + P
Sbjct: 119 CPDSSTCCHMLDGSWGCCPMPQASCCEDRVHCCPHGASCDLVHIRCVTALGSHPLTTKLP 178
Query: 174 VVETIDSAKIETPKYT--VERSTLREFMIKIGDKNNCPDG-GQCAGLQTCCLMYTGHYGC 344
T + TP + + + L +I CPD QC TCCL+ +G YGC
Sbjct: 179 AQRTNYTGAEGTPVVSPGLLPAALPTSVI-------CPDSRSQCPDDTTCCLLASGEYGC 231
Query: 345 CPFSLGVCCPDLRTCCAPGYHC 410
CP +CC D CC C
Sbjct: 232 CPMPNAICCSDHLHCCPQDTVC 253
Score = 71.2 bits (173), Expect = 1e-12
Identities = 39/137 (28%), Positives = 51/137 (37%), Gaps = 1/137 (0%)
Frame = +3
Query: 3 CGDQKTCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVE 182
C +C + +G CC +S A+ CGD HCCP G C CI + P +
Sbjct: 53 CPIGHSCVLTAAGTAACCPFSQAMACGDGHHCCPYGFHCSTDGGTCIQR-------PDIH 105
Query: 183 TIDSAKIETPKYTVERSTLREFMIKIGDKNNCPDGG-QCAGLQTCCLMYTGHYGCCPFSL 359
+ + + CP G +C TCC M G +GCCP
Sbjct: 106 LLGAVQ-------------------------CPGGEFECPDSSTCCHMLDGSWGCCPMPQ 140
Query: 360 GVCCPDLRTCCAPGYHC 410
CC D CC G C
Sbjct: 141 ASCCEDRVHCCPHGASC 157
Score = 66.6 bits (161), Expect = 3e-11
Identities = 35/123 (28%), Positives = 50/123 (40%)
Frame = +3
Query: 3 CGDQKTCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVE 182
C + +TCC +SG CC + AVCC D +HCCPE C C Q + W
Sbjct: 289 CPEGQTCCRLQSGKWGCCPFPKAVCCEDHVHCCPERFRCHTEKDTC-EQGLLQVPWAQKT 347
Query: 183 TIDSAKIETPKYTVERSTLREFMIKIGDKNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLG 362
++ P + + +C + C CC + +G +GCCP S G
Sbjct: 348 PAQPSRPSQPSPPGPPGPPSP-PGPLRSEISCDEVVSCRPGNICCRLASGEWGCCPSSEG 406
Query: 363 VCC 371
C
Sbjct: 407 YLC 409
Score = 66.6 bits (161), Expect = 3e-11
Identities = 23/51 (45%), Positives = 30/51 (58%)
Frame = +3
Query: 3 CGDQKTCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSN 155
C D++TCC GG CC + VCC DQ HCCP G C+ RC+H+ +
Sbjct: 524 CHDEQTCCRDSRGGWACCPFHQGVCCKDQRHCCPAGFHCESQGTRCVHKKS 574
Score = 47.0 bits (110), Expect = 3e-05
Identities = 33/125 (26%), Positives = 50/125 (40%), Gaps = 2/125 (1%)
Frame = +3
Query: 42 GHQCCQYSNAVCCGDQLHCCP--EGTTCDLVNKRCIHQSNEPIEWPVVETIDSAKIETPK 215
G+ CC+ ++ + CCP EG C + +RC V + + K+
Sbjct: 387 GNICCRLASG-----EWGCCPSSEGYLC-MAGERC----------QVGDRLAPEKMAAHL 430
Query: 216 YTVERSTLREFMIKIGDKNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCA 395
++ ++T +G C C QTCC G + CC VCC D + CC
Sbjct: 431 MSLSQTT------DVG----CDQHASCPVRQTCCPKLGGGWACCQLPHAVCCEDGQHCCP 480
Query: 396 PGYHC 410
GY C
Sbjct: 481 AGYTC 485
Score = 46.6 bits (109), Expect = 3e-05
Identities = 21/50 (42%), Positives = 24/50 (48%)
Frame = +3
Query: 273 NCPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHCVTGG 422
NCP G +C L G CCPFS + C D CC G+HC T G
Sbjct: 52 NCPIG------HSCVLTAAGTAACCPFSQAMACGDGHHCCPYGFHCSTDG 95
>sp|P80059|PMD1_LOCMI Pars intercerebralis major peptide D1 (PMP-D1)
Length = 54
Score = 63.5 bits (153), Expect = 3e-10
Identities = 23/47 (48%), Positives = 28/47 (59%)
Frame = +3
Query: 3 CGDQKTCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCI 143
C +TCC + G CC Y VCC D +HCCP GT CD ++RCI
Sbjct: 7 CPGTETCCTTPQGEEGCCPYKEGVCCLDGIHCCPSGTVCDEDHRRCI 53
Score = 48.9 bits (115), Expect = 7e-06
Identities = 19/39 (48%), Positives = 21/39 (53%)
Frame = +3
Query: 294 CAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHC 410
C G +TCC G GCCP+ GVCC D CC G C
Sbjct: 7 CPGTETCCTTPQGEEGCCPYKEGVCCLDGIHCCPSGTVC 45
>sp|P80930|ENA1_HORSE Antimicrobial peptide eNAP-1
Length = 46
Score = 59.3 bits (142), Expect = 5e-09
Identities = 21/36 (58%), Positives = 23/36 (63%)
Frame = +3
Query: 3 CGDQKTCCASKSGGHQCCQYSNAVCCGDQLHCCPEG 110
C D +TCC + GG CC YS VCC DQ HCCP G
Sbjct: 10 CHDXQTCCRASQGGXACCPYSQGVCCADQRHCCPVG 45
Score = 53.9 bits (128), Expect = 2e-07
Identities = 21/43 (48%), Positives = 24/43 (55%)
Frame = +3
Query: 276 CPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGY 404
C +G C QTCC G CCP+S GVCC D R CC G+
Sbjct: 4 CGEGHFCHDXQTCCRASQGGXACCPYSQGVCCADQRHCCPVGF 46
>sp|P81013|GRN1_CYPCA Granulin-1
Length = 57
Score = 55.5 bits (132), Expect = 7e-08
Identities = 24/45 (53%), Positives = 26/45 (57%)
Frame = +3
Query: 276 CPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHC 410
CPDG TCCL G + CCPFS+G CC D CC GYHC
Sbjct: 10 CPDG------TTCCLSPYGVWYCCPFSMGQCCRDGIHCCRHGYHC 48
Score = 52.8 bits (125), Expect = 5e-07
Identities = 20/47 (42%), Positives = 24/47 (51%)
Frame = +3
Query: 3 CGDQKTCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCI 143
C D TCC S G CC +S CC D +HCC G CD + C+
Sbjct: 10 CPDGTTCCLSPYGVWYCCPFSMGQCCRDGIHCCRHGYHCDSTSTHCL 56
>sp|P81015|GRN3_CYPCA Granulin-3
Length = 57
Score = 53.9 bits (128), Expect = 2e-07
Identities = 22/45 (48%), Positives = 24/45 (53%)
Frame = +3
Query: 276 CPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHC 410
C G C TCC G + CCPF +G CC D R CC GYHC
Sbjct: 4 CDAGITCPSGTTCCRSPFGVWYCCPFLMGQCCRDGRHCCRHGYHC 48
Score = 45.8 bits (107), Expect = 6e-05
Identities = 18/47 (38%), Positives = 21/47 (44%)
Frame = +3
Query: 3 CGDQKTCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCI 143
C TCC S G CC + CC D HCC G CD + C+
Sbjct: 10 CPSGTTCCRSPFGVWYCCPFLMGQCCRDGRHCCRHGYHCDSTSTLCL 56
>sp|P81014|GRN2_CYPCA Granulin-2
Length = 57
Score = 48.9 bits (115), Expect = 7e-06
Identities = 19/39 (48%), Positives = 21/39 (53%)
Frame = +3
Query: 294 CAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHC 410
C TCC G + CCPF +G CC D R CC GY C
Sbjct: 10 CPSRTTCCRSPFGVWYCCPFLMGQCCRDGRHCCRHGYRC 48
Score = 47.4 bits (111), Expect = 2e-05
Identities = 18/47 (38%), Positives = 22/47 (46%)
Frame = +3
Query: 3 CGDQKTCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCI 143
C + TCC S G CC + CC D HCC G CD + C+
Sbjct: 10 CPSRTTCCRSPFGVWYCCPFLMGQCCRDGRHCCRHGYRCDSTSTLCL 56
>sp|P25777|ORYB_ORYSA Oryzain beta chain precursor
Length = 471
Score = 43.5 bits (101), Expect = 3e-04
Identities = 19/50 (38%), Positives = 24/50 (48%), Gaps = 3/50 (6%)
Frame = +3
Query: 264 DKNNCPDGGQCA---GLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGY 404
D +CP G C G + CL++ GCCP CC D +CC P Y
Sbjct: 387 DNFSCPAGSTCCCAFGFRNLCLVW----GCCPVEGATCCKDHASCCPPDY 432
Score = 33.1 bits (74), Expect = 0.39
Identities = 17/60 (28%), Positives = 22/60 (36%), Gaps = 6/60 (10%)
Frame = +3
Query: 3 CGDQKTCCASKSGGHQC-----CQYSNAVCCGDQLHCC-PEGTTCDLVNKRCIHQSNEPI 164
C TCC + + C C A CC D CC P+ C+ C N P+
Sbjct: 391 CPAGSTCCCAFGFRNLCLVWGCCPVEGATCCKDHASCCPPDYPVCNTRAGTCSASKNSPL 450
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 62,075,353
Number of Sequences: 369166
Number of extensions: 1391644
Number of successful extensions: 4945
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4254
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4829
length of database: 68,354,980
effective HSP length: 103
effective length of database: 49,327,275
effective search space used: 3255600150
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)