Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_021_C12
(225 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P28797|GRN_CAVPO Granulins precursor (Proepithelin) (PEP... 56 3e-08
sp|P28799|GRN_HUMAN Granulins precursor (Proepithelin) (PEP... 53 2e-07
sp|P28798|GRN_MOUSE Granulins precursor (Acrogranin) (Proep... 52 3e-07
sp|P23785|GRN_RAT Granulins precursor [Contains: Acrogranin... 52 3e-07
sp|P81013|GRN1_CYPCA Granulin-1 52 5e-07
sp|P81015|GRN3_CYPCA Granulin-3 50 2e-06
sp|P80930|ENA1_HORSE Antimicrobial peptide eNAP-1 48 6e-06
sp|P81014|GRN2_CYPCA Granulin-2 47 1e-05
sp|P80059|PMD1_LOCMI Pars intercerebralis major peptide D1 ... 46 3e-05
sp|P43297|RD21A_ARATH Cysteine proteinase RD21a precursor (... 37 0.014
>sp|P28797|GRN_CAVPO Granulins precursor (Proepithelin) (PEPI) [Contains: Acrogranin;
Granulin-1; Granulin-2; Granulin-3; Granulin-4;
Granulin-5; Granulin-6; Granulin-7]
Length = 591
Score = 55.8 bits (133), Expect = 3e-08
Identities = 21/39 (53%), Positives = 24/39 (61%)
Frame = +2
Query: 20 QTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHCVTGG 136
QTCC G + CCPF GVCC D R CC G+HC + G
Sbjct: 528 QTCCRDSRGGWACCPFHQGVCCKDQRHCCPAGFHCESQG 566
Score = 49.3 bits (116), Expect = 3e-06
Identities = 18/37 (48%), Positives = 22/37 (59%)
Frame = +2
Query: 20 QTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHCVT 130
QTCC + +G +GCCPF VCC D CC + C T
Sbjct: 293 QTCCRLQSGKWGCCPFPKAVCCEDHVHCCPERFRCHT 329
Score = 45.4 bits (106), Expect = 4e-05
Identities = 16/34 (47%), Positives = 19/34 (55%)
Frame = +2
Query: 23 TCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHC 124
TCCL+ +G YGCCP +CC D CC C
Sbjct: 220 TCCLLASGEYGCCPMPNAICCSDHLHCCPQDTVC 253
Score = 43.5 bits (101), Expect = 1e-04
Identities = 17/38 (44%), Positives = 20/38 (52%)
Frame = +2
Query: 23 TCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHCVTGG 136
+C L G CCPFS + C D CC G+HC T G
Sbjct: 58 SCVLTAAGTAACCPFSQAMACGDGHHCCPYGFHCSTDG 95
Score = 42.7 bits (99), Expect = 3e-04
Identities = 16/34 (47%), Positives = 17/34 (50%)
Frame = +2
Query: 23 TCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHC 124
TCC M G +GCCP CC D CC G C
Sbjct: 124 TCCHMLDGSWGCCPMPQASCCEDRVHCCPHGASC 157
Score = 42.4 bits (98), Expect = 3e-04
Identities = 16/35 (45%), Positives = 18/35 (51%)
Frame = +2
Query: 20 QTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHC 124
QTCC G + CC VCC D + CC GY C
Sbjct: 451 QTCCPKLGGGWACCQLPHAVCCEDGQHCCPAGYTC 485
Score = 30.8 bits (68), Expect = 0.99
Identities = 10/20 (50%), Positives = 13/20 (65%)
Frame = +2
Query: 26 CCLMYTGHYGCCPFSLGVCC 85
CC + +G +GCCP S G C
Sbjct: 390 CCRLASGEWGCCPSSEGYLC 409
>sp|P28799|GRN_HUMAN Granulins precursor (Proepithelin) (PEPI) [Contains: Acrogranin;
Paragranulin; Granulin-1 (Granulin G); Granulin-2
(Granulin F); Granulin-3 (Granulin B); Granulin-4
(Granulin A); Granulin-5 (Granulin C); Granulin-6
(Granulin D); Granulin-7 (Granulin E)]
Length = 593
Score = 52.8 bits (125), Expect = 2e-07
Identities = 21/44 (47%), Positives = 25/44 (56%)
Frame = +2
Query: 23 TCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHCVTGGCA*LGS 154
TCC + +G +GCCP VCC D + CC GY CV G GS
Sbjct: 377 TCCQLTSGEWGCCPIPEAVCCSDHQHCCPQGYTCVAEGQCQRGS 420
Score = 50.1 bits (118), Expect = 2e-06
Identities = 18/36 (50%), Positives = 23/36 (63%)
Frame = +2
Query: 23 TCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHCVT 130
TCC + +G +GCCPF+ VCC D CC G+ C T
Sbjct: 295 TCCRLQSGAWGCCPFTQAVCCEDHIHCCPAGFTCDT 330
Score = 48.9 bits (115), Expect = 4e-06
Identities = 18/39 (46%), Positives = 21/39 (53%)
Frame = +2
Query: 20 QTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHCVTGG 136
QTCC + CCP+ GVCC D R CC G+ C G
Sbjct: 531 QTCCRDNRQGWACCPYRQGVCCADRRHCCPAGFRCAARG 569
Score = 44.3 bits (103), Expect = 9e-05
Identities = 16/34 (47%), Positives = 18/34 (52%)
Frame = +2
Query: 23 TCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHC 124
TCC+M G +GCCP CC D CC G C
Sbjct: 138 TCCVMVDGSWGCCPMPQASCCEDRVHCCPHGAFC 171
Score = 43.5 bits (101), Expect = 1e-04
Identities = 16/35 (45%), Positives = 18/35 (51%)
Frame = +2
Query: 20 QTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHC 124
QTCC G + CC VCC D + CC GY C
Sbjct: 454 QTCCPSLGGSWACCQLPHAVCCEDRQHCCPAGYTC 488
Score = 40.8 bits (94), Expect = 0.001
Identities = 15/34 (44%), Positives = 17/34 (50%)
Frame = +2
Query: 23 TCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHC 124
TCC + +G YGCCP CC D CC C
Sbjct: 220 TCCELPSGKYGCCPMPNATCCSDHLHCCPQDTVC 253
Score = 40.0 bits (92), Expect = 0.002
Identities = 15/38 (39%), Positives = 18/38 (47%)
Frame = +2
Query: 23 TCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHCVTGG 136
+C +G CCPF V C D CC G+HC G
Sbjct: 72 SCIFTVSGTSSCCPFPEAVACGDGHHCCPRGFHCSADG 109
>sp|P28798|GRN_MOUSE Granulins precursor (Acrogranin) (Proepithelin) (PEPI) (PC
cell-derived growth factor) (PCDGF) [Contains: Granulin
1; Granulin 2; Granulin 3; Granulin 4; Granulin 5;
Granulin 6; Granulin 7]
Length = 589
Score = 52.4 bits (124), Expect = 3e-07
Identities = 20/39 (51%), Positives = 23/39 (58%)
Frame = +2
Query: 20 QTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHCVTGG 136
QTCC G + CCP+ GVCC D R CC G+HC G
Sbjct: 527 QTCCKDSAGVWACCPYLKGVCCRDGRHCCPGGFHCSARG 565
Score = 52.0 bits (123), Expect = 4e-07
Identities = 19/36 (52%), Positives = 23/36 (63%)
Frame = +2
Query: 23 TCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHCVT 130
TCC + TG +GCCPF+ VCC D CC G+ C T
Sbjct: 293 TCCRLNTGAWGCCPFAKAVCCEDHIHCCPAGFQCHT 328
Score = 49.3 bits (116), Expect = 3e-06
Identities = 17/38 (44%), Positives = 23/38 (60%)
Frame = +2
Query: 23 TCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHCVTGG 136
TCC + +G +GCCP VCC D + CC G+ C+ G
Sbjct: 375 TCCKLNSGDWGCCPIPEAVCCSDNQHCCPQGFTCLAQG 412
Score = 45.4 bits (106), Expect = 4e-05
Identities = 18/38 (47%), Positives = 21/38 (55%)
Frame = +2
Query: 23 TCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHCVTGG 136
+C L +G CCPFS GV C D CC G+HC G
Sbjct: 72 SCLLTVSGTSSCCPFSKGVSCGDGYHCCPQGFHCSADG 109
Score = 44.7 bits (104), Expect = 7e-05
Identities = 16/34 (47%), Positives = 18/34 (52%)
Frame = +2
Query: 23 TCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHC 124
TCC+M G +GCCP CC D CC G C
Sbjct: 137 TCCIMVDGSWGCCPMPQASCCEDRVHCCPHGASC 170
Score = 43.9 bits (102), Expect = 1e-04
Identities = 16/35 (45%), Positives = 18/35 (51%)
Frame = +2
Query: 20 QTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHC 124
QTCC G + CC VCC D + CC GY C
Sbjct: 452 QTCCPSLKGSWACCQLPHAVCCEDRQHCCPAGYTC 486
Score = 43.5 bits (101), Expect = 1e-04
Identities = 16/34 (47%), Positives = 18/34 (52%)
Frame = +2
Query: 23 TCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHC 124
TCC + TG YGCCP +CC D CC C
Sbjct: 219 TCCELPTGKYGCCPMPNAICCSDHLHCCPQDTVC 252
>sp|P23785|GRN_RAT Granulins precursor [Contains: Acrogranin; Granulin-1 (Granulin G);
Granulin-2 (Granulin F); Granulin-3 (Granulin B)
(Epithelin-2); Granulin-4 (Granulin A) (Epithelin-1);
Granulin-5 (Granulin C); Granulin-6 (Granulin D);
Granulin-7 (Granulin E)]
Length = 588
Score = 52.4 bits (124), Expect = 3e-07
Identities = 21/41 (51%), Positives = 25/41 (60%), Gaps = 2/41 (4%)
Frame = +2
Query: 23 TCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHC--VTGGC 139
TCC + TG +GCCPF+ VCC D CC G+ C TG C
Sbjct: 292 TCCRLNTGAWGCCPFTKAVCCEDHIHCCPAGFQCHTETGTC 332
Score = 50.4 bits (119), Expect = 1e-06
Identities = 19/39 (48%), Positives = 23/39 (58%)
Frame = +2
Query: 20 QTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHCVTGG 136
Q+CC G + CCP+ GVCC D R CC G+HC G
Sbjct: 526 QSCCKDSQGGWACCPYVKGVCCRDGRHCCPIGFHCSAKG 564
Score = 48.5 bits (114), Expect = 5e-06
Identities = 17/38 (44%), Positives = 23/38 (60%)
Frame = +2
Query: 23 TCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHCVTGG 136
TCC + +G +GCCP VCC D + CC G+ C+ G
Sbjct: 374 TCCRLSSGDWGCCPMPEAVCCLDHQHCCPQGFKCMDEG 411
Score = 46.2 bits (108), Expect = 2e-05
Identities = 18/38 (47%), Positives = 22/38 (57%)
Frame = +2
Query: 23 TCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHCVTGG 136
+C L +G CCPFS GV C D + CC G+HC G
Sbjct: 72 SCLLTVSGTSSCCPFSEGVSCDDGQHCCPRGFHCSADG 109
Score = 44.7 bits (104), Expect = 7e-05
Identities = 16/34 (47%), Positives = 18/34 (52%)
Frame = +2
Query: 23 TCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHC 124
TCC+M G +GCCP CC D CC G C
Sbjct: 137 TCCIMIDGSWGCCPMPQASCCEDRVHCCPHGASC 170
Score = 43.9 bits (102), Expect = 1e-04
Identities = 16/35 (45%), Positives = 18/35 (51%)
Frame = +2
Query: 20 QTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHC 124
QTCC G + CC VCC D + CC GY C
Sbjct: 451 QTCCPSLKGSWACCQLPHAVCCEDRQHCCPAGYTC 485
Score = 43.5 bits (101), Expect = 1e-04
Identities = 16/34 (47%), Positives = 18/34 (52%)
Frame = +2
Query: 23 TCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHC 124
TCC + TG YGCCP +CC D CC C
Sbjct: 218 TCCELPTGKYGCCPMPNAICCSDHLHCCPQDTVC 251
>sp|P81013|GRN1_CYPCA Granulin-1
Length = 57
Score = 51.6 bits (122), Expect = 5e-07
Identities = 20/34 (58%), Positives = 22/34 (64%)
Frame = +2
Query: 23 TCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHC 124
TCCL G + CCPFS+G CC D CC GYHC
Sbjct: 15 TCCLSPYGVWYCCPFSMGQCCRDGIHCCRHGYHC 48
>sp|P81015|GRN3_CYPCA Granulin-3
Length = 57
Score = 50.1 bits (118), Expect = 2e-06
Identities = 19/34 (55%), Positives = 21/34 (61%)
Frame = +2
Query: 23 TCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHC 124
TCC G + CCPF +G CC D R CC GYHC
Sbjct: 15 TCCRSPFGVWYCCPFLMGQCCRDGRHCCRHGYHC 48
>sp|P80930|ENA1_HORSE Antimicrobial peptide eNAP-1
Length = 46
Score = 48.1 bits (113), Expect = 6e-06
Identities = 18/33 (54%), Positives = 20/33 (60%)
Frame = +2
Query: 20 QTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGY 118
QTCC G CCP+S GVCC D R CC G+
Sbjct: 14 QTCCRASQGGXACCPYSQGVCCADQRHCCPVGF 46
>sp|P81014|GRN2_CYPCA Granulin-2
Length = 57
Score = 47.0 bits (110), Expect = 1e-05
Identities = 18/34 (52%), Positives = 20/34 (58%)
Frame = +2
Query: 23 TCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHC 124
TCC G + CCPF +G CC D R CC GY C
Sbjct: 15 TCCRSPFGVWYCCPFLMGQCCRDGRHCCRHGYRC 48
>sp|P80059|PMD1_LOCMI Pars intercerebralis major peptide D1 (PMP-D1)
Length = 54
Score = 45.8 bits (107), Expect = 3e-05
Identities = 18/37 (48%), Positives = 20/37 (54%)
Frame = +2
Query: 14 GLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHC 124
G +TCC G GCCP+ GVCC D CC G C
Sbjct: 9 GTETCCTTPQGEEGCCPYKEGVCCLDGIHCCPSGTVC 45
>sp|P43297|RD21A_ARATH Cysteine proteinase RD21a precursor (RD21)
Length = 462
Score = 37.0 bits (84), Expect = 0.014
Identities = 15/35 (42%), Positives = 16/35 (45%), Gaps = 4/35 (11%)
Frame = +2
Query: 26 CCLMYTGHY----GCCPFSLGVCCPDLRTCCAPGY 118
CCL G Y GCCP CC D +CC Y
Sbjct: 388 CCLFEYGKYCFAWGCCPLEAATCCDDNYSCCPHEY 422
Score = 30.4 bits (67), Expect = 1.3
Identities = 13/34 (38%), Positives = 17/34 (50%)
Frame = +2
Query: 23 TCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHC 124
TCC ++ YG F+ G C + TCC Y C
Sbjct: 386 TCCCLF--EYGKYCFAWGCCPLEAATCCDDNYSC 417
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 28,294,226
Number of Sequences: 369166
Number of extensions: 538969
Number of successful extensions: 1577
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 1452
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 1572
length of database: 68,354,980
effective HSP length: 46
effective length of database: 59,857,170
effective search space used: 1676000760
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)