Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_012_A19
(470 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P23785|GRN_RAT Granulins precursor [Contains: Acrogranin... 96 3e-20
sp|P28799|GRN_HUMAN Granulins precursor (Proepithelin) (PEP... 94 1e-19
sp|P28798|GRN_MOUSE Granulins precursor (Acrogranin) (Proep... 94 2e-19
sp|P28797|GRN_CAVPO Granulins precursor (Proepithelin) (PEP... 92 5e-19
sp|P81013|GRN1_CYPCA Granulin-1 55 6e-08
sp|P81015|GRN3_CYPCA Granulin-3 54 2e-07
sp|P80930|ENA1_HORSE Antimicrobial peptide eNAP-1 54 2e-07
sp|P80059|PMD1_LOCMI Pars intercerebralis major peptide D1 ... 52 9e-07
sp|P81014|GRN2_CYPCA Granulin-2 49 6e-06
sp|P25777|ORYB_ORYSA Oryzain beta chain precursor 44 2e-04
>sp|P23785|GRN_RAT Granulins precursor [Contains: Acrogranin; Granulin-1 (Granulin G);
Granulin-2 (Granulin F); Granulin-3 (Granulin B)
(Epithelin-2); Granulin-4 (Granulin A) (Epithelin-1);
Granulin-5 (Granulin C); Granulin-6 (Granulin D);
Granulin-7 (Granulin E)]
Length = 588
Score = 96.3 bits (238), Expect = 3e-20
Identities = 47/127 (37%), Positives = 61/127 (48%), Gaps = 2/127 (1%)
Frame = +1
Query: 10 CCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVETIDSAKIETPKYTVER 189
CC NA+CC D LHCCP+ T CDL+ +CI + + + P Y V
Sbjct: 229 CCPMPNAICCSDHLHCCPQDTVCDLIQSKCISK----------DYTTDLMTKLPGYPVNE 278
Query: 190 STLREFMIKIGDKNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHC 369
+K + +CPDG TCC + TG +GCCPF+ VCC D CC G+ C
Sbjct: 279 -------VKCDLEVSCPDG------YTCCRLNTGAWGCCPFTKAVCCEDHIHCCPAGFQC 325
Query: 370 --VTGGC 384
TG C
Sbjct: 326 HTETGTC 332
Score = 84.3 bits (207), Expect = 1e-16
Identities = 44/124 (35%), Positives = 57/124 (45%)
Frame = +1
Query: 10 CCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVETIDSAKIETPKYTVER 189
CCQ +AVCC D+ HCCP G TC++ + C E +V+
Sbjct: 463 CCQLPHAVCCEDRQHCCPAGYTCNVKARTC---------------------EKDAGSVQP 501
Query: 190 STLREFMIKIGDKNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHC 369
S F K+G+ C G C Q+CC G + CCP+ GVCC D R CC G+HC
Sbjct: 502 SMDLTFGSKVGNVE-CGAGHFCHDNQSCCKDSQGGWACCPYVKGVCCRDGRHCCPIGFHC 560
Query: 370 VTGG 381
G
Sbjct: 561 SAKG 564
Score = 82.8 bits (203), Expect = 4e-16
Identities = 41/120 (34%), Positives = 55/120 (45%)
Frame = +1
Query: 10 CCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVETIDSAKIETPKYTVER 189
CC A CC D++HCCP G +CDLV+ RCI + P+++ + P R
Sbjct: 148 CCPMPQASCCEDRVHCCPHGASCDLVHTRCISPTG---THPLLK-------KFPAQRTNR 197
Query: 190 STLREFMIKIGDKNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHC 369
+ ++ K CPD TCC + TG YGCCP +CC D CC C
Sbjct: 198 AVASFSVVCPDAKTQCPDD------STCCELPTGKYGCCPMPNAICCSDHLHCCPQDTVC 251
Score = 78.6 bits (192), Expect = 7e-15
Identities = 37/124 (29%), Positives = 57/124 (45%)
Frame = +1
Query: 10 CCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVETIDSAKIETPKYTVER 189
CC ++ AVCC D +HCCP G C C ++ P ++ + +A + P + +
Sbjct: 303 CCPFTKAVCCEDHIHCCPAGFQCHTETGTC---ELGVLQVPWMKKV-TASLSLPDPQILK 358
Query: 190 STLREFMIKIGDKNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHC 369
+ + C D C TCC + +G +GCCP VCC D + CC G+ C
Sbjct: 359 NDVP-----------CDDFSSCPSNNTCCRLSSGDWGCCPMPEAVCCLDHQHCCPQGFKC 407
Query: 370 VTGG 381
+ G
Sbjct: 408 MDEG 411
Score = 67.8 bits (164), Expect = 1e-11
Identities = 36/120 (30%), Positives = 44/120 (36%)
Frame = +1
Query: 10 CCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVETIDSAKIETPKYTVER 189
CC +S V C D HCCP G C K C S+ + ++ P
Sbjct: 83 CCPFSEGVSCDDGQHCCPRGFHCSADGKSCSQISDSLL----------GAVQCP------ 126
Query: 190 STLREFMIKIGDKNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHC 369
G + CPD TCC+M G +GCCP CC D CC G C
Sbjct: 127 ----------GSQFECPDSA------TCCIMIDGSWGCCPMPQASCCEDRVHCCPHGASC 170
Score = 66.2 bits (160), Expect = 3e-11
Identities = 38/120 (31%), Positives = 48/120 (40%)
Frame = +1
Query: 10 CCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVETIDSAKIETPKYTVER 189
CC AVCC D HCCP+G C ++ + D K V +
Sbjct: 385 CCPMPEAVCCLDHQHCCPQGFKC--------------MDEGYCQKGDRMVAGLEKMPVRQ 430
Query: 190 STLREFMIKIGDKNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHC 369
+TL ++ GD C C QTCC G + CC VCC D + CC GY C
Sbjct: 431 TTL----LQHGDIG-CDQHTSCPVGQTCCPSLKGSWACCQLPHAVCCEDRQHCCPAGYTC 485
Score = 51.6 bits (122), Expect = 9e-07
Identities = 22/52 (42%), Positives = 29/52 (55%)
Frame = +1
Query: 226 KNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHCVTGG 381
+++CPDG +C L +G CCPFS GV C D + CC G+HC G
Sbjct: 64 RDHCPDG------YSCLLTVSGTSSCCPFSEGVSCDDGQHCCPRGFHCSADG 109
Score = 42.4 bits (98), Expect = 5e-04
Identities = 15/36 (41%), Positives = 18/36 (50%)
Frame = +1
Query: 1 GHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQ 108
G CC Y VCC D HCCP G C +C+ +
Sbjct: 535 GWACCPYVKGVCCRDGRHCCPIGFHCSAKGTKCLRK 570
>sp|P28799|GRN_HUMAN Granulins precursor (Proepithelin) (PEPI) [Contains: Acrogranin;
Paragranulin; Granulin-1 (Granulin G); Granulin-2
(Granulin F); Granulin-3 (Granulin B); Granulin-4
(Granulin A); Granulin-5 (Granulin C); Granulin-6
(Granulin D); Granulin-7 (Granulin E)]
Length = 593
Score = 94.4 bits (233), Expect = 1e-19
Identities = 44/122 (36%), Positives = 60/122 (49%)
Frame = +1
Query: 10 CCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVETIDSAKIETPKYTVER 189
CC NA CC D LHCCP+ T CDL+ +C+ + N + + P +TV
Sbjct: 231 CCPMPNATCCSDHLHCCPQDTVCDLIQSKCLSKENATTD---------LLTKLPAHTVGD 281
Query: 190 STLREFMIKIGDKNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHC 369
+K + +CPDG TCC + +G +GCCPF+ VCC D CC G+ C
Sbjct: 282 -------VKCDMEVSCPDG------YTCCRLQSGAWGCCPFTQAVCCEDHIHCCPAGFTC 328
Query: 370 VT 375
T
Sbjct: 329 DT 330
Score = 86.7 bits (213), Expect = 2e-17
Identities = 43/130 (33%), Positives = 56/130 (43%)
Frame = +1
Query: 10 CCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVETIDSAKIETPKYTVER 189
CC ++ AVCC D +HCCP G TCD C P + P +E + ++R
Sbjct: 306 CCPFTQAVCCEDHIHCCPAGFTCDTQKGTC---EQGPHQVPWMEKAPAHLSLPDPQALKR 362
Query: 190 STLREFMIKIGDKNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHC 369
C + C TCC + +G +GCCP VCC D + CC GY C
Sbjct: 363 DV------------PCDNVSSCPSSDTCCQLTSGEWGCCPIPEAVCCSDHQHCCPQGYTC 410
Query: 370 VTGGCA*LGS 399
V G GS
Sbjct: 411 VAEGQCQRGS 420
Score = 82.0 bits (201), Expect = 6e-16
Identities = 41/125 (32%), Positives = 55/125 (44%), Gaps = 1/125 (0%)
Frame = +1
Query: 10 CCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVETIDSAKIETPKYTVER 189
CCQ +AVCC D+ HCCP G TC++ + C E + +
Sbjct: 466 CCQLPHAVCCEDRQHCCPAGYTCNVKARSC---------------------EKEVVSAQP 504
Query: 190 STLREFMIKIGDKN-NCPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYH 366
+T +G K+ C +G C QTCC + CCP+ GVCC D R CC G+
Sbjct: 505 ATFLARSPHVGVKDVECGEGHFCHDNQTCCRDNRQGWACCPYRQGVCCADRRHCCPAGFR 564
Query: 367 CVTGG 381
C G
Sbjct: 565 CAARG 569
Score = 80.9 bits (198), Expect = 1e-15
Identities = 43/121 (35%), Positives = 54/121 (44%), Gaps = 1/121 (0%)
Frame = +1
Query: 10 CCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVETIDSAKIETPKYTVER 189
CC A CC D++HCCP G CDLV+ RCI + T AK + P R
Sbjct: 149 CCPMPQASCCEDRVHCCPHGAFCDLVHTRCITPTG---------THPLAK-KLPAQRTNR 198
Query: 190 STLREFMIKIGD-KNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYH 366
+ + D ++ CPDG TCC + +G YGCCP CC D CC
Sbjct: 199 AVALSSSVMCPDARSRCPDG------STCCELPSGKYGCCPMPNATCCSDHLHCCPQDTV 252
Query: 367 C 369
C
Sbjct: 253 C 253
Score = 69.7 bits (169), Expect = 3e-12
Identities = 35/121 (28%), Positives = 42/121 (34%), Gaps = 1/121 (0%)
Frame = +1
Query: 10 CCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVETIDSAKIETPKYTVER 189
CC + AV CGD HCCP G C + C +S +
Sbjct: 83 CCPFPEAVACGDGHHCCPRGFHCSADGRSCFQRSGNNSVGAI------------------ 124
Query: 190 STLREFMIKIGDKNNCPDGG-QCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYH 366
CPD +C TCC+M G +GCCP CC D CC G
Sbjct: 125 --------------QCPDSQFECPDFSTCCVMVDGSWGCCPMPQASCCEDRVHCCPHGAF 170
Query: 367 C 369
C
Sbjct: 171 C 171
Score = 68.9 bits (167), Expect = 5e-12
Identities = 40/120 (33%), Positives = 49/120 (40%)
Frame = +1
Query: 10 CCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVETIDSAKIETPKYTVER 189
CC AVCC D HCCP+G TC + +C S I + + P
Sbjct: 388 CCPIPEAVCCSDHQHCCPQGYTC-VAEGQCQRGSE----------IVAGLEKMPARRASL 436
Query: 190 STLREFMIKIGDKNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHC 369
S R+ I +CP G QTCC G + CC VCC D + CC GY C
Sbjct: 437 SHPRD--IGCDQHTSCPVG------QTCCPSLGGSWACCQLPHAVCCEDRQHCCPAGYTC 488
Score = 44.7 bits (104), Expect = 1e-04
Identities = 15/36 (41%), Positives = 19/36 (52%)
Frame = +1
Query: 1 GHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQ 108
G CC Y VCC D+ HCCP G C +C+ +
Sbjct: 540 GWACCPYRQGVCCADRRHCCPAGFRCAARGTKCLRR 575
Score = 43.9 bits (102), Expect = 2e-04
Identities = 17/49 (34%), Positives = 21/49 (42%)
Frame = +1
Query: 235 CPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHCVTGG 381
C C+ +C +G CCPF V C D CC G+HC G
Sbjct: 61 CQVDAHCSAGHSCIFTVSGTSSCCPFPEAVACGDGHHCCPRGFHCSADG 109
>sp|P28798|GRN_MOUSE Granulins precursor (Acrogranin) (Proepithelin) (PEPI) (PC
cell-derived growth factor) (PCDGF) [Contains: Granulin
1; Granulin 2; Granulin 3; Granulin 4; Granulin 5;
Granulin 6; Granulin 7]
Length = 589
Score = 94.0 bits (232), Expect = 2e-19
Identities = 45/122 (36%), Positives = 62/122 (50%)
Frame = +1
Query: 10 CCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVETIDSAKIETPKYTVER 189
CC NA+CC D LHCCP+ T CDL+ +C+ ++ T D + P Y V+
Sbjct: 230 CCPMPNAICCSDHLHCCPQDTVCDLIQSKCLSKN---------YTTD-LLTKLPGYPVKE 279
Query: 190 STLREFMIKIGDKNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHC 369
+K + +CP+G TCC + TG +GCCPF+ VCC D CC G+ C
Sbjct: 280 -------VKCDMEVSCPEG------YTCCRLNTGAWGCCPFAKAVCCEDHIHCCPAGFQC 326
Query: 370 VT 375
T
Sbjct: 327 HT 328
Score = 87.8 bits (216), Expect = 1e-17
Identities = 45/124 (36%), Positives = 61/124 (49%)
Frame = +1
Query: 10 CCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVETIDSAKIETPKYTVER 189
CCQ +AVCC D+ HCCP G TC++ + C + + I+ PV+ T+
Sbjct: 464 CCQLPHAVCCEDRQHCCPAGYTCNVKARTC-EKDVDFIQPPVLLTLGP------------ 510
Query: 190 STLREFMIKIGDKNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHC 369
K+G+ C +G C QTCC G + CCP+ GVCC D R CC G+HC
Sbjct: 511 --------KVGNVE-CGEGHFCHDNQTCCKDSAGVWACCPYLKGVCCRDGRHCCPGGFHC 561
Query: 370 VTGG 381
G
Sbjct: 562 SARG 565
Score = 82.8 bits (203), Expect = 4e-16
Identities = 41/121 (33%), Positives = 53/121 (43%), Gaps = 1/121 (0%)
Frame = +1
Query: 10 CCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVETIDSAKIETPKYTVER 189
CC A CC D++HCCP G +CDLV+ RC+ + + + P R
Sbjct: 148 CCPMPQASCCEDRVHCCPHGASCDLVHTRCVSPTG----------THTLLKKFPAQKTNR 197
Query: 190 STLREFMIKIGD-KNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYH 366
+ F + D K CPD TCC + TG YGCCP +CC D CC
Sbjct: 198 AVSLPFSVVCPDAKTQCPDD------STCCELPTGKYGCCPMPNAICCSDHLHCCPQDTV 251
Query: 367 C 369
C
Sbjct: 252 C 252
Score = 80.9 bits (198), Expect = 1e-15
Identities = 38/124 (30%), Positives = 54/124 (43%)
Frame = +1
Query: 10 CCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVETIDSAKIETPKYTVER 189
CC ++ AVCC D +HCCP G C H E +++ K+ P +
Sbjct: 304 CCPFAKAVCCEDHIHCCPAGFQC--------HTEKGTCEMGILQVPWMKKVIAPLRLPDP 355
Query: 190 STLREFMIKIGDKNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHC 369
L+ C D +C TCC + +G +GCCP VCC D + CC G+ C
Sbjct: 356 QILKS-------DTPCDDFTRCPTNNTCCKLNSGDWGCCPIPEAVCCSDNQHCCPQGFTC 408
Query: 370 VTGG 381
+ G
Sbjct: 409 LAQG 412
Score = 77.4 bits (189), Expect = 2e-14
Identities = 38/120 (31%), Positives = 47/120 (39%)
Frame = +1
Query: 10 CCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVETIDSAKIETPKYTVER 189
CC +S V CGD HCCP+G C K C S+ P+ ++ P
Sbjct: 83 CCPFSKGVSCGDGYHCCPQGFHCSADGKSCFQMSDNPL----------GAVQCP------ 126
Query: 190 STLREFMIKIGDKNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHC 369
G + CPD TCC+M G +GCCP CC D CC G C
Sbjct: 127 ----------GSQFECPDSA------TCCIMVDGSWGCCPMPQASCCEDRVHCCPHGASC 170
Score = 70.9 bits (172), Expect = 1e-12
Identities = 41/121 (33%), Positives = 50/121 (41%), Gaps = 1/121 (0%)
Frame = +1
Query: 10 CCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVETIDSAKIETPKYTVER 189
CC AVCC D HCCP+G TC L C K +T +E+
Sbjct: 386 CCPIPEAVCCSDNQHCCPQGFTC-LAQGYC------------------QKGDTMVAGLEK 426
Query: 190 STLREFM-IKIGDKNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYH 366
R+ ++IGD C C QTCC G + CC VCC D + CC GY
Sbjct: 427 IPARQTTPLQIGDIG-CDQHTSCPVGQTCCPSLKGSWACCQLPHAVCCEDRQHCCPAGYT 485
Query: 367 C 369
C
Sbjct: 486 C 486
Score = 51.2 bits (121), Expect = 1e-06
Identities = 21/50 (42%), Positives = 25/50 (50%)
Frame = +1
Query: 232 NCPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHCVTGG 381
+C G C +C L +G CCPFS GV C D CC G+HC G
Sbjct: 60 SCQTHGHCPAGYSCLLTVSGTSSCCPFSKGVSCGDGYHCCPQGFHCSADG 109
Score = 41.2 bits (95), Expect = 0.001
Identities = 14/33 (42%), Positives = 17/33 (51%)
Frame = +1
Query: 10 CCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQ 108
CC Y VCC D HCCP G C +C+ +
Sbjct: 539 CCPYLKGVCCRDGRHCCPGGFHCSARGTKCLRK 571
>sp|P28797|GRN_CAVPO Granulins precursor (Proepithelin) (PEPI) [Contains: Acrogranin;
Granulin-1; Granulin-2; Granulin-3; Granulin-4;
Granulin-5; Granulin-6; Granulin-7]
Length = 591
Score = 92.4 bits (228), Expect = 5e-19
Identities = 43/122 (35%), Positives = 60/122 (49%)
Frame = +1
Query: 10 CCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVETIDSAKIETPKYTVER 189
CC NA+CC D LHCCP+ T CDL RC+ Q+ + + P +TV
Sbjct: 231 CCPMPNAICCSDHLHCCPQDTVCDLRQSRCLSQNK----------AKTLLTKLPSWTV-- 278
Query: 190 STLREFMIKIGDKNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHC 369
+ ++ + +CP+G QTCC + +G +GCCPF VCC D CC + C
Sbjct: 279 -----WDVECDQEVSCPEG------QTCCRLQSGKWGCCPFPKAVCCEDHVHCCPERFRC 327
Query: 370 VT 375
T
Sbjct: 328 HT 329
Score = 89.7 bits (221), Expect = 3e-18
Identities = 47/127 (37%), Positives = 59/127 (46%)
Frame = +1
Query: 1 GHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVETIDSAKIETPKYT 180
G CCQ +AVCC D HCCP G TC++ + C + D A + P
Sbjct: 460 GWACCQLPHAVCCEDGQHCCPAGYTCNVKARSC------------EKAADGAHLAAP--L 505
Query: 181 VERSTLREFMIKIGDKNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPG 360
ST + GD++ C D QTCC G + CCPF GVCC D R CC G
Sbjct: 506 AVGSTGGVMDVACGDRHFCHDE------QTCCRDSRGGWACCPFHQGVCCKDQRHCCPAG 559
Query: 361 YHCVTGG 381
+HC + G
Sbjct: 560 FHCESQG 566
Score = 82.4 bits (202), Expect = 5e-16
Identities = 45/126 (35%), Positives = 61/126 (48%), Gaps = 6/126 (4%)
Frame = +1
Query: 10 CCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQ-SNEPI--EWPVVETIDSAKIETPKYT 180
CC A CC D++HCCP G +CDLV+ RC+ + P+ + P T + TP +
Sbjct: 135 CCPMPQASCCEDRVHCCPHGASCDLVHIRCVTALGSHPLTTKLPAQRTNYTGAEGTPVVS 194
Query: 181 --VERSTLREFMIKIGDKNNCPDG-GQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCC 351
+ + L +I CPD QC TCCL+ +G YGCCP +CC D CC
Sbjct: 195 PGLLPAALPTSVI-------CPDSRSQCPDDTTCCLLASGEYGCCPMPNAICCSDHLHCC 247
Query: 352 APGYHC 369
C
Sbjct: 248 PQDTVC 253
Score = 67.0 bits (162), Expect = 2e-11
Identities = 36/121 (29%), Positives = 45/121 (37%), Gaps = 1/121 (0%)
Frame = +1
Query: 10 CCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVETIDSAKIETPKYTVER 189
CC +S A+ CGD HCCP G C CI + P + + + +
Sbjct: 69 CCPFSQAMACGDGHHCCPYGFHCSTDGGTCIQR-------PDIHLLGAVQ---------- 111
Query: 190 STLREFMIKIGDKNNCPDGG-QCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYH 366
CP G +C TCC M G +GCCP CC D CC G
Sbjct: 112 ---------------CPGGEFECPDSSTCCHMLDGSWGCCPMPQASCCEDRVHCCPHGAS 156
Query: 367 C 369
C
Sbjct: 157 C 157
Score = 53.9 bits (128), Expect = 2e-07
Identities = 29/107 (27%), Positives = 41/107 (38%)
Frame = +1
Query: 10 CCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVETIDSAKIETPKYTVER 189
CC + AVCC D +HCCPE C C Q + W ++ P
Sbjct: 305 CCPFPKAVCCEDHVHCCPERFRCHTEKDTC-EQGLLQVPWAQKTPAQPSRPSQPSPPGPP 363
Query: 190 STLREFMIKIGDKNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCC 330
+ + +C + C CC + +G +GCCP S G C
Sbjct: 364 GPPSP-PGPLRSEISCDEVVSCRPGNICCRLASGEWGCCPSSEGYLC 409
Score = 50.1 bits (118), Expect = 3e-06
Identities = 17/38 (44%), Positives = 22/38 (57%)
Frame = +1
Query: 1 GHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSN 114
G CC + VCC DQ HCCP G C+ RC+H+ +
Sbjct: 537 GWACCPFHQGVCCKDQRHCCPAGFHCESQGTRCVHKKS 574
Score = 47.0 bits (110), Expect = 2e-05
Identities = 33/125 (26%), Positives = 50/125 (40%), Gaps = 2/125 (1%)
Frame = +1
Query: 1 GHQCCQYSNAVCCGDQLHCCP--EGTTCDLVNKRCIHQSNEPIEWPVVETIDSAKIETPK 174
G+ CC+ ++ + CCP EG C + +RC V + + K+
Sbjct: 387 GNICCRLASG-----EWGCCPSSEGYLC-MAGERC----------QVGDRLAPEKMAAHL 430
Query: 175 YTVERSTLREFMIKIGDKNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCA 354
++ ++T +G C C QTCC G + CC VCC D + CC
Sbjct: 431 MSLSQTT------DVG----CDQHASCPVRQTCCPKLGGGWACCQLPHAVCCEDGQHCCP 480
Query: 355 PGYHC 369
GY C
Sbjct: 481 AGYTC 485
Score = 46.6 bits (109), Expect = 3e-05
Identities = 21/50 (42%), Positives = 24/50 (48%)
Frame = +1
Query: 232 NCPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHCVTGG 381
NCP G +C L G CCPFS + C D CC G+HC T G
Sbjct: 52 NCPIG------HSCVLTAAGTAACCPFSQAMACGDGHHCCPYGFHCSTDG 95
>sp|P81013|GRN1_CYPCA Granulin-1
Length = 57
Score = 55.5 bits (132), Expect = 6e-08
Identities = 24/45 (53%), Positives = 26/45 (57%)
Frame = +1
Query: 235 CPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHC 369
CPDG TCCL G + CCPFS+G CC D CC GYHC
Sbjct: 10 CPDG------TTCCLSPYGVWYCCPFSMGQCCRDGIHCCRHGYHC 48
Score = 40.0 bits (92), Expect = 0.003
Identities = 13/31 (41%), Positives = 17/31 (54%)
Frame = +1
Query: 10 CCQYSNAVCCGDQLHCCPEGTTCDLVNKRCI 102
CC +S CC D +HCC G CD + C+
Sbjct: 26 CCPFSMGQCCRDGIHCCRHGYHCDSTSTHCL 56
>sp|P81015|GRN3_CYPCA Granulin-3
Length = 57
Score = 53.9 bits (128), Expect = 2e-07
Identities = 22/45 (48%), Positives = 24/45 (53%)
Frame = +1
Query: 235 CPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHC 369
C G C TCC G + CCPF +G CC D R CC GYHC
Sbjct: 4 CDAGITCPSGTTCCRSPFGVWYCCPFLMGQCCRDGRHCCRHGYHC 48
Score = 35.4 bits (80), Expect = 0.066
Identities = 12/31 (38%), Positives = 15/31 (48%)
Frame = +1
Query: 10 CCQYSNAVCCGDQLHCCPEGTTCDLVNKRCI 102
CC + CC D HCC G CD + C+
Sbjct: 26 CCPFLMGQCCRDGRHCCRHGYHCDSTSTLCL 56
>sp|P80930|ENA1_HORSE Antimicrobial peptide eNAP-1
Length = 46
Score = 53.9 bits (128), Expect = 2e-07
Identities = 21/43 (48%), Positives = 24/43 (55%)
Frame = +1
Query: 235 CPDGGQCAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGY 363
C +G C QTCC G CCP+S GVCC D R CC G+
Sbjct: 4 CGEGHFCHDXQTCCRASQGGXACCPYSQGVCCADQRHCCPVGF 46
Score = 43.1 bits (100), Expect = 3e-04
Identities = 15/23 (65%), Positives = 15/23 (65%)
Frame = +1
Query: 1 GHQCCQYSNAVCCGDQLHCCPEG 69
G CC YS VCC DQ HCCP G
Sbjct: 23 GXACCPYSQGVCCADQRHCCPVG 45
>sp|P80059|PMD1_LOCMI Pars intercerebralis major peptide D1 (PMP-D1)
Length = 54
Score = 51.6 bits (122), Expect = 9e-07
Identities = 18/31 (58%), Positives = 21/31 (67%)
Frame = +1
Query: 10 CCQYSNAVCCGDQLHCCPEGTTCDLVNKRCI 102
CC Y VCC D +HCCP GT CD ++RCI
Sbjct: 23 CCPYKEGVCCLDGIHCCPSGTVCDEDHRRCI 53
Score = 48.9 bits (115), Expect = 6e-06
Identities = 19/39 (48%), Positives = 21/39 (53%)
Frame = +1
Query: 253 CAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHC 369
C G +TCC G GCCP+ GVCC D CC G C
Sbjct: 7 CPGTETCCTTPQGEEGCCPYKEGVCCLDGIHCCPSGTVC 45
>sp|P81014|GRN2_CYPCA Granulin-2
Length = 57
Score = 48.9 bits (115), Expect = 6e-06
Identities = 19/39 (48%), Positives = 21/39 (53%)
Frame = +1
Query: 253 CAGLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGYHC 369
C TCC G + CCPF +G CC D R CC GY C
Sbjct: 10 CPSRTTCCRSPFGVWYCCPFLMGQCCRDGRHCCRHGYRC 48
Score = 35.8 bits (81), Expect = 0.050
Identities = 12/31 (38%), Positives = 15/31 (48%)
Frame = +1
Query: 10 CCQYSNAVCCGDQLHCCPEGTTCDLVNKRCI 102
CC + CC D HCC G CD + C+
Sbjct: 26 CCPFLMGQCCRDGRHCCRHGYRCDSTSTLCL 56
>sp|P25777|ORYB_ORYSA Oryzain beta chain precursor
Length = 471
Score = 43.5 bits (101), Expect = 2e-04
Identities = 19/50 (38%), Positives = 24/50 (48%), Gaps = 3/50 (6%)
Frame = +1
Query: 223 DKNNCPDGGQCA---GLQTCCLMYTGHYGCCPFSLGVCCPDLRTCCAPGY 363
D +CP G C G + CL++ GCCP CC D +CC P Y
Sbjct: 387 DNFSCPAGSTCCCAFGFRNLCLVW----GCCPVEGATCCKDHASCCPPDY 432
Score = 32.3 bits (72), Expect = 0.56
Identities = 13/39 (33%), Positives = 16/39 (41%), Gaps = 1/39 (2%)
Frame = +1
Query: 10 CCQYSNAVCCGDQLHCC-PEGTTCDLVNKRCIHQSNEPI 123
CC A CC D CC P+ C+ C N P+
Sbjct: 412 CCPVEGATCCKDHASCCPPDYPVCNTRAGTCSASKNSPL 450
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 57,015,854
Number of Sequences: 369166
Number of extensions: 1249855
Number of successful extensions: 4305
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3858
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4227
length of database: 68,354,980
effective HSP length: 101
effective length of database: 49,696,745
effective search space used: 2733320975
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)