Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_022_C09
(487 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P28797|GRN_CAVPO Granulins precursor (Proepithelin) (PEP... 111 8e-25
sp|P23785|GRN_RAT Granulins precursor [Contains: Acrogranin... 109 4e-24
sp|P28798|GRN_MOUSE Granulins precursor (Acrogranin) (Proep... 107 1e-23
sp|P28799|GRN_HUMAN Granulins precursor (Proepithelin) (PEP... 107 1e-23
sp|P80059|PMD1_LOCMI Pars intercerebralis major peptide D1 ... 64 2e-10
sp|P80930|ENA1_HORSE Antimicrobial peptide eNAP-1 59 5e-09
sp|P81013|GRN1_CYPCA Granulin-1 54 2e-07
sp|P81014|GRN2_CYPCA Granulin-2 50 3e-06
sp|P81015|GRN3_CYPCA Granulin-3 46 5e-05
sp|P43297|RD21A_ARATH Cysteine proteinase RD21a precursor (... 43 4e-04
>sp|P28797|GRN_CAVPO Granulins precursor (Proepithelin) (PEPI) [Contains: Acrogranin;
Granulin-1; Granulin-2; Granulin-3; Granulin-4;
Granulin-5; Granulin-6; Granulin-7]
Length = 591
Score = 111 bits (278), Expect = 8e-25
Identities = 55/151 (36%), Positives = 77/151 (50%), Gaps = 3/151 (1%)
Frame = +1
Query: 43 TPGLLKENLN---ICQNGKALCGDQKTCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTC 213
+PGLL L IC + ++ C D TCC SG + CC NA+CC D LHCCP+ T C
Sbjct: 194 SPGLLPAALPTSVICPDSRSQCPDDTTCCLLASGEYGCCPMPNAICCSDHLHCCPQDTVC 253
Query: 214 DLVNKRCIHQSNEPIEWPVVETIDSAKIETPKYTVERSTLREFMIKIGDKNNCPDGGQCA 393
DL RC+ Q+ + + P +TV + ++ + +CP+G
Sbjct: 254 DLRQSRCLSQNK----------AKTLLTKLPSWTV-------WDVECDQEVSCPEG---- 292
Query: 394 GLQTCCLMYTGHYGCCPFSLSVCCPDLRTCC 486
QTCC + +G +GCCPF +VCC D CC
Sbjct: 293 --QTCCRLQSGKWGCCPFPKAVCCEDHVHCC 321
Score = 99.0 bits (245), Expect = 5e-21
Identities = 52/143 (36%), Positives = 70/143 (48%), Gaps = 6/143 (4%)
Frame = +1
Query: 76 CQNGKALCGDQKTCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQ-SNE 252
C G+ C D TCC G CC A CC D++HCCP G +CDLV+ RC+ +
Sbjct: 112 CPGGEFECPDSSTCCHMLDGSWGCCPMPQASCCEDRVHCCPHGASCDLVHIRCVTALGSH 171
Query: 253 PI--EWPVVETIDSAKIETPKYT--VERSTLREFMIKIGDKNNCPDG-GQCAGLQTCCLM 417
P+ + P T + TP + + + L +I CPD QC TCCL+
Sbjct: 172 PLTTKLPAQRTNYTGAEGTPVVSPGLLPAALPTSVI-------CPDSRSQCPDDTTCCLL 224
Query: 418 YTGHYGCCPFSLSVCCPDLRTCC 486
+G YGCCP ++CC D CC
Sbjct: 225 ASGEYGCCPMPNAICCSDHLHCC 247
Score = 90.5 bits (223), Expect = 2e-18
Identities = 49/144 (34%), Positives = 65/144 (45%)
Frame = +1
Query: 55 LKENLNICQNGKALCGDQKTCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRC 234
L + ++ + A C ++TCC GG CCQ +AVCC D HCCP G TC++ + C
Sbjct: 433 LSQTTDVGCDQHASCPVRQTCCPKLGGGWACCQLPHAVCCEDGQHCCPAGYTCNVKARSC 492
Query: 235 IHQSNEPIEWPVVETIDSAKIETPKYTVERSTLREFMIKIGDKNNCPDGGQCAGLQTCCL 414
+ D A + P ST + GD++ C D QTCC
Sbjct: 493 ------------EKAADGAHLAAP--LAVGSTGGVMDVACGDRHFCHDE------QTCCR 532
Query: 415 MYTGHYGCCPFSLSVCCPDLRTCC 486
G + CCPF VCC D R CC
Sbjct: 533 DSRGGWACCPFHQGVCCKDQRHCC 556
Score = 69.3 bits (168), Expect = 4e-12
Identities = 40/138 (28%), Positives = 54/138 (39%), Gaps = 1/138 (0%)
Frame = +1
Query: 76 CQNGKALCGDQKTCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEP 255
CQ+ A C +C + +G CC +S A+ CGD HCCP G C CI +
Sbjct: 47 CQS-PANCPIGHSCVLTAAGTAACCPFSQAMACGDGHHCCPYGFHCSTDGGTCIQR---- 101
Query: 256 IEWPVVETIDSAKIETPKYTVERSTLREFMIKIGDKNNCPDGG-QCAGLQTCCLMYTGHY 432
P + + + + CP G +C TCC M G +
Sbjct: 102 ---PDIHLLGAVQ-------------------------CPGGEFECPDSSTCCHMLDGSW 133
Query: 433 GCCPFSLSVCCPDLRTCC 486
GCCP + CC D CC
Sbjct: 134 GCCPMPQASCCEDRVHCC 151
Score = 67.4 bits (163), Expect = 2e-11
Identities = 23/61 (37%), Positives = 34/61 (55%)
Frame = +1
Query: 67 LNICQNGKALCGDQKTCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQS 246
+++ + C D++TCC GG CC + VCC DQ HCCP G C+ RC+H+
Sbjct: 514 MDVACGDRHFCHDEQTCCRDSRGGWACCPFHQGVCCKDQRHCCPAGFHCESQGTRCVHKK 573
Query: 247 N 249
+
Sbjct: 574 S 574
Score = 64.3 bits (155), Expect = 1e-10
Identities = 34/123 (27%), Positives = 49/123 (39%)
Frame = +1
Query: 97 CGDQKTCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVE 276
C + +TCC +SG CC + AVCC D +HCCPE C C Q + W
Sbjct: 289 CPEGQTCCRLQSGKWGCCPFPKAVCCEDHVHCCPERFRCHTEKDTC-EQGLLQVPWAQKT 347
Query: 277 TIDSAKIETPKYTVERSTLREFMIKIGDKNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLS 456
++ P + + +C + C CC + +G +GCCP S
Sbjct: 348 PAQPSRPSQPSPPGPPGPPSP-PGPLRSEISCDEVVSCRPGNICCRLASGEWGCCPSSEG 406
Query: 457 VCC 465
C
Sbjct: 407 YLC 409
>sp|P23785|GRN_RAT Granulins precursor [Contains: Acrogranin; Granulin-1 (Granulin G);
Granulin-2 (Granulin F); Granulin-3 (Granulin B)
(Epithelin-2); Granulin-4 (Granulin A) (Epithelin-1);
Granulin-5 (Granulin C); Granulin-6 (Granulin D);
Granulin-7 (Granulin E)]
Length = 588
Score = 109 bits (272), Expect = 4e-24
Identities = 50/138 (36%), Positives = 68/138 (49%)
Frame = +1
Query: 73 ICQNGKALCGDQKTCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNE 252
+C + K C D TCC +G + CC NA+CC D LHCCP+ T CDL+ +CI +
Sbjct: 205 VCPDAKTQCPDDSTCCELPTGKYGCCPMPNAICCSDHLHCCPQDTVCDLIQSKCISK--- 261
Query: 253 PIEWPVVETIDSAKIETPKYTVERSTLREFMIKIGDKNNCPDGGQCAGLQTCCLMYTGHY 432
+ + P Y V +K + +CPDG TCC + TG +
Sbjct: 262 -------DYTTDLMTKLPGYPVNE-------VKCDLEVSCPDG------YTCCRLNTGAW 301
Query: 433 GCCPFSLSVCCPDLRTCC 486
GCCPF+ +VCC D CC
Sbjct: 302 GCCPFTKAVCCEDHIHCC 319
Score = 96.7 bits (239), Expect = 3e-20
Identities = 47/137 (34%), Positives = 63/137 (45%)
Frame = +1
Query: 76 CQNGKALCGDQKTCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEP 255
C + C D TCC G CC A CC D++HCCP G +CDLV+ RCI +
Sbjct: 125 CPGSQFECPDSATCCIMIDGSWGCCPMPQASCCEDRVHCCPHGASCDLVHTRCISPTG-- 182
Query: 256 IEWPVVETIDSAKIETPKYTVERSTLREFMIKIGDKNNCPDGGQCAGLQTCCLMYTGHYG 435
P+++ + P R+ ++ K CPD TCC + TG YG
Sbjct: 183 -THPLLK-------KFPAQRTNRAVASFSVVCPDAKTQCPDD------STCCELPTGKYG 228
Query: 436 CCPFSLSVCCPDLRTCC 486
CCP ++CC D CC
Sbjct: 229 CCPMPNAICCSDHLHCC 245
Score = 84.3 bits (207), Expect = 1e-16
Identities = 45/130 (34%), Positives = 58/130 (44%)
Frame = +1
Query: 97 CGDQKTCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVE 276
C +TCC S G CCQ +AVCC D+ HCCP G TC++ + C
Sbjct: 447 CPVGQTCCPSLKGSWACCQLPHAVCCEDRQHCCPAGYTCNVKARTC-------------- 492
Query: 277 TIDSAKIETPKYTVERSTLREFMIKIGDKNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLS 456
E +V+ S F K+G+ C G C Q+CC G + CCP+
Sbjct: 493 -------EKDAGSVQPSMDLTFGSKVGNV-ECGAGHFCHDNQSCCKDSQGGWACCPYVKG 544
Query: 457 VCCPDLRTCC 486
VCC D R CC
Sbjct: 545 VCCRDGRHCC 554
Score = 84.0 bits (206), Expect = 2e-16
Identities = 40/130 (30%), Positives = 60/130 (46%)
Frame = +1
Query: 97 CGDQKTCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVE 276
C D TCC +G CC ++ AVCC D +HCCP G C C ++ P ++
Sbjct: 287 CPDGYTCCRLNTGAWGCCPFTKAVCCEDHIHCCPAGFQCHTETGTC---ELGVLQVPWMK 343
Query: 277 TIDSAKIETPKYTVERSTLREFMIKIGDKNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLS 456
+ +A + P + ++ + C D C TCC + +G +GCCP +
Sbjct: 344 KV-TASLSLPDPQILKNDV-----------PCDDFSSCPSNNTCCRLSSGDWGCCPMPEA 391
Query: 457 VCCPDLRTCC 486
VCC D + CC
Sbjct: 392 VCCLDHQHCC 401
Score = 73.6 bits (179), Expect = 2e-13
Identities = 39/130 (30%), Positives = 50/130 (38%)
Frame = +1
Query: 97 CGDQKTCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVE 276
C D +C + SG CC +S V C D HCCP G C K C S+ +
Sbjct: 67 CPDGYSCLLTVSGTSSCCPFSEGVSCDDGQHCCPRGFHCSADGKSCSQISDSLL------ 120
Query: 277 TIDSAKIETPKYTVERSTLREFMIKIGDKNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLS 456
++ P G + CPD TCC+M G +GCCP +
Sbjct: 121 ----GAVQCP----------------GSQFECPDSA------TCCIMIDGSWGCCPMPQA 154
Query: 457 VCCPDLRTCC 486
CC D CC
Sbjct: 155 SCCEDRVHCC 164
Score = 72.0 bits (175), Expect = 7e-13
Identities = 41/130 (31%), Positives = 52/130 (40%)
Frame = +1
Query: 97 CGDQKTCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVE 276
C TCC SG CC AVCC D HCCP+G C ++ +
Sbjct: 369 CPSNNTCCRLSSGDWGCCPMPEAVCCLDHQHCCPQGFKC--------------MDEGYCQ 414
Query: 277 TIDSAKIETPKYTVERSTLREFMIKIGDKNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLS 456
D K V ++TL ++ GD C C QTCC G + CC +
Sbjct: 415 KGDRMVAGLEKMPVRQTTL----LQHGD-IGCDQHTSCPVGQTCCPSLKGSWACCQLPHA 469
Query: 457 VCCPDLRTCC 486
VCC D + CC
Sbjct: 470 VCCEDRQHCC 479
Score = 60.1 bits (144), Expect = 3e-09
Identities = 25/86 (29%), Positives = 37/86 (43%), Gaps = 9/86 (10%)
Frame = +1
Query: 13 CNILQHVIAKTPGLLKENLNICQNGKA---------LCGDQKTCCASKSGGHQCCQYSNA 165
CN+ K G ++ ++++ K C D ++CC GG CC Y
Sbjct: 485 CNVKARTCEKDAGSVQPSMDLTFGSKVGNVECGAGHFCHDNQSCCKDSQGGWACCPYVKG 544
Query: 166 VCCGDQLHCCPEGTTCDLVNKRCIHQ 243
VCC D HCCP G C +C+ +
Sbjct: 545 VCCRDGRHCCPIGFHCSAKGTKCLRK 570
Score = 39.3 bits (90), Expect = 0.005
Identities = 17/42 (40%), Positives = 23/42 (54%)
Frame = +1
Query: 361 KNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLSVCCPDLRTCC 486
+++CPDG +C L +G CCPFS V C D + CC
Sbjct: 64 RDHCPDG------YSCLLTVSGTSSCCPFSEGVSCDDGQHCC 99
>sp|P28798|GRN_MOUSE Granulins precursor (Acrogranin) (Proepithelin) (PEPI) (PC
cell-derived growth factor) (PCDGF) [Contains: Granulin
1; Granulin 2; Granulin 3; Granulin 4; Granulin 5;
Granulin 6; Granulin 7]
Length = 589
Score = 107 bits (267), Expect = 1e-23
Identities = 50/138 (36%), Positives = 71/138 (51%)
Frame = +1
Query: 73 ICQNGKALCGDQKTCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNE 252
+C + K C D TCC +G + CC NA+CC D LHCCP+ T CDL+ +C+ ++
Sbjct: 206 VCPDAKTQCPDDSTCCELPTGKYGCCPMPNAICCSDHLHCCPQDTVCDLIQSKCLSKN-- 263
Query: 253 PIEWPVVETIDSAKIETPKYTVERSTLREFMIKIGDKNNCPDGGQCAGLQTCCLMYTGHY 432
T D + P Y V+ +K + +CP+G TCC + TG +
Sbjct: 264 -------YTTD-LLTKLPGYPVKE-------VKCDMEVSCPEG------YTCCRLNTGAW 302
Query: 433 GCCPFSLSVCCPDLRTCC 486
GCCPF+ +VCC D CC
Sbjct: 303 GCCPFAKAVCCEDHIHCC 320
Score = 97.1 bits (240), Expect = 2e-20
Identities = 47/138 (34%), Positives = 61/138 (44%), Gaps = 1/138 (0%)
Frame = +1
Query: 76 CQNGKALCGDQKTCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEP 255
C + C D TCC G CC A CC D++HCCP G +CDLV+ RC+ +
Sbjct: 125 CPGSQFECPDSATCCIMVDGSWGCCPMPQASCCEDRVHCCPHGASCDLVHTRCVSPTG-- 182
Query: 256 IEWPVVETIDSAKIETPKYTVERSTLREFMIKIGD-KNNCPDGGQCAGLQTCCLMYTGHY 432
+ + P R+ F + D K CPD TCC + TG Y
Sbjct: 183 --------THTLLKKFPAQKTNRAVSLPFSVVCPDAKTQCPDD------STCCELPTGKY 228
Query: 433 GCCPFSLSVCCPDLRTCC 486
GCCP ++CC D CC
Sbjct: 229 GCCPMPNAICCSDHLHCC 246
Score = 87.4 bits (215), Expect = 2e-17
Identities = 46/130 (35%), Positives = 62/130 (47%)
Frame = +1
Query: 97 CGDQKTCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVE 276
C +TCC S G CCQ +AVCC D+ HCCP G TC++ + C + + I+ PV+
Sbjct: 448 CPVGQTCCPSLKGSWACCQLPHAVCCEDRQHCCPAGYTCNVKARTC-EKDVDFIQPPVLL 506
Query: 277 TIDSAKIETPKYTVERSTLREFMIKIGDKNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLS 456
T+ K+G+ C +G C QTCC G + CCP+
Sbjct: 507 TLGP--------------------KVGNV-ECGEGHFCHDNQTCCKDSAGVWACCPYLKG 545
Query: 457 VCCPDLRTCC 486
VCC D R CC
Sbjct: 546 VCCRDGRHCC 555
Score = 85.1 bits (209), Expect = 8e-17
Identities = 44/157 (28%), Positives = 67/157 (42%)
Frame = +1
Query: 16 NILQHVIAKTPGLLKENLNICQNGKALCGDQKTCCASKSGGHQCCQYSNAVCCGDQLHCC 195
N ++ K PG + + + + C + TCC +G CC ++ AVCC D +HCC
Sbjct: 263 NYTTDLLTKLPGYPVKEVKC--DMEVSCPEGYTCCRLNTGAWGCCPFAKAVCCEDHIHCC 320
Query: 196 PEGTTCDLVNKRCIHQSNEPIEWPVVETIDSAKIETPKYTVERSTLREFMIKIGDKNNCP 375
P G C H E +++ K+ P + L+ C
Sbjct: 321 PAGFQC--------HTEKGTCEMGILQVPWMKKVIAPLRLPDPQILK-------SDTPCD 365
Query: 376 DGGQCAGLQTCCLMYTGHYGCCPFSLSVCCPDLRTCC 486
D +C TCC + +G +GCCP +VCC D + CC
Sbjct: 366 DFTRCPTNNTCCKLNSGDWGCCPIPEAVCCSDNQHCC 402
Score = 80.1 bits (196), Expect = 2e-15
Identities = 40/130 (30%), Positives = 52/130 (40%)
Frame = +1
Query: 97 CGDQKTCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVE 276
C +C + SG CC +S V CGD HCCP+G C K C S+ P+
Sbjct: 67 CPAGYSCLLTVSGTSSCCPFSKGVSCGDGYHCCPQGFHCSADGKSCFQMSDNPL------ 120
Query: 277 TIDSAKIETPKYTVERSTLREFMIKIGDKNNCPDGGQCAGLQTCCLMYTGHYGCCPFSLS 456
++ P G + CPD TCC+M G +GCCP +
Sbjct: 121 ----GAVQCP----------------GSQFECPDSA------TCCIMVDGSWGCCPMPQA 154
Query: 457 VCCPDLRTCC 486
CC D CC
Sbjct: 155 SCCEDRVHCC 164
Score = 76.3 bits (186), Expect = 4e-14
Identities = 44/131 (33%), Positives = 54/131 (41%), Gaps = 1/131 (0%)
Frame = +1
Query: 97 CGDQKTCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVE 276
C TCC SG CC AVCC D HCCP+G TC L C
Sbjct: 370 CPTNNTCCKLNSGDWGCCPIPEAVCCSDNQHCCPQGFTC-LAQGYC-------------- 414
Query: 277 TIDSAKIETPKYTVERSTLREFM-IKIGDKNNCPDGGQCAGLQTCCLMYTGHYGCCPFSL 453
K +T +E+ R+ ++IGD C C QTCC G + CC
Sbjct: 415 ----QKGDTMVAGLEKIPARQTTPLQIGD-IGCDQHTSCPVGQTCCPSLKGSWACCQLPH 469
Query: 454 SVCCPDLRTCC 486
+VCC D + CC
Sbjct: 470 AVCCEDRQHCC 480
Score = 55.5 bits (132), Expect = 7e-08
Identities = 20/49 (40%), Positives = 25/49 (51%)
Frame = +1
Query: 97 CGDQKTCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQ 243
C D +TCC +G CC Y VCC D HCCP G C +C+ +
Sbjct: 523 CHDNQTCCKDSAGVWACCPYLKGVCCRDGRHCCPGGFHCSARGTKCLRK 571
Score = 38.5 bits (88), Expect = 0.008
Identities = 16/40 (40%), Positives = 19/40 (47%)
Frame = +1
Query: 367 NCPDGGQCAGLQTCCLMYTGHYGCCPFSLSVCCPDLRTCC 486
+C G C +C L +G CCPFS V C D CC
Sbjct: 60 SCQTHGHCPAGYSCLLTVSGTSSCCPFSKGVSCGDGYHCC 99
>sp|P28799|GRN_HUMAN Granulins precursor (Proepithelin) (PEPI) [Contains: Acrogranin;
Paragranulin; Granulin-1 (Granulin G); Granulin-2
(Granulin F); Granulin-3 (Granulin B); Granulin-4
(Granulin A); Granulin-5 (Granulin C); Granulin-6
(Granulin D); Granulin-7 (Granulin E)]
Length = 593
Score = 107 bits (267), Expect = 1e-23
Identities = 49/138 (35%), Positives = 70/138 (50%)
Frame = +1
Query: 73 ICQNGKALCGDQKTCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNE 252
+C + ++ C D TCC SG + CC NA CC D LHCCP+ T CDL+ +C+ + N
Sbjct: 207 MCPDARSRCPDGSTCCELPSGKYGCCPMPNATCCSDHLHCCPQDTVCDLIQSKCLSKENA 266
Query: 253 PIEWPVVETIDSAKIETPKYTVERSTLREFMIKIGDKNNCPDGGQCAGLQTCCLMYTGHY 432
+ + P +TV +K + +CPDG TCC + +G +
Sbjct: 267 TTD---------LLTKLPAHTVGD-------VKCDMEVSCPDG------YTCCRLQSGAW 304
Query: 433 GCCPFSLSVCCPDLRTCC 486
GCCPF+ +VCC D CC
Sbjct: 305 GCCPFTQAVCCEDHIHCC 322
Score = 95.1 bits (235), Expect = 7e-20
Identities = 49/138 (35%), Positives = 63/138 (45%), Gaps = 1/138 (0%)
Frame = +1
Query: 76 CQNGKALCGDQKTCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEP 255
C + + C D TCC G CC A CC D++HCCP G CDLV+ RCI +
Sbjct: 126 CPDSQFECPDFSTCCVMVDGSWGCCPMPQASCCEDRVHCCPHGAFCDLVHTRCITPTG-- 183
Query: 256 IEWPVVETIDSAKIETPKYTVERSTLREFMIKIGD-KNNCPDGGQCAGLQTCCLMYTGHY 432
T AK + P R+ + D ++ CPDG TCC + +G Y
Sbjct: 184 -------THPLAK-KLPAQRTNRAVALSSSVMCPDARSRCPDG------STCCELPSGKY 229
Query: 433 GCCPFSLSVCCPDLRTCC 486
GCCP + CC D CC
Sbjct: 230 GCCPMPNATCCSDHLHCC 247
Score = 90.9 bits (224), Expect = 1e-18
Identities = 48/157 (30%), Positives = 70/157 (44%)
Frame = +1
Query: 16 NILQHVIAKTPGLLKENLNICQNGKALCGDQKTCCASKSGGHQCCQYSNAVCCGDQLHCC 195
++L + A T G +K ++ + C D TCC +SG CC ++ AVCC D +HCC
Sbjct: 269 DLLTKLPAHTVGDVKCDMEVS------CPDGYTCCRLQSGAWGCCPFTQAVCCEDHIHCC 322
Query: 196 PEGTTCDLVNKRCIHQSNEPIEWPVVETIDSAKIETPKYTVERSTLREFMIKIGDKNNCP 375
P G TCD C P + P +E + ++R C
Sbjct: 323 PAGFTCDTQKGTC---EQGPHQVPWMEKAPAHLSLPDPQALKRDV------------PCD 367
Query: 376 DGGQCAGLQTCCLMYTGHYGCCPFSLSVCCPDLRTCC 486
+ C TCC + +G +GCCP +VCC D + CC
Sbjct: 368 NVSSCPSSDTCCQLTSGEWGCCPIPEAVCCSDHQHCC 404
Score = 83.6 bits (205), Expect = 2e-16
Identities = 43/131 (32%), Positives = 57/131 (43%), Gaps = 1/131 (0%)
Frame = +1
Query: 97 CGDQKTCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQSNEPIEWPVVE 276
C +TCC S G CCQ +AVCC D+ HCCP G TC++ + C
Sbjct: 450 CPVGQTCCPSLGGSWACCQLPHAVCCEDRQHCCPAGYTCNVKARSC-------------- 495
Query: 277 TIDSAKIETPKYTVERSTLREFMIKIGDKN-NCPDGGQCAGLQTCCLMYTGHYGCCPFSL 453
E + + +T +G K+ C +G C QTCC + CCP+
Sbjct: 496 -------EKEVVSAQPATFLARSPHVGVKDVECGEGHFCHDNQTCCRDNRQGWACCPYRQ 548
Query: 454 SVCCPDLRTCC 486
VCC D R CC
Sbjct: 549 GVCCADRRHCC 559
Score = 75.9 bits (185), Expect = 5e-14
Identities = 47/153 (30%), Positives = 62/153 (40%)
Frame = +1
Query: 28 HVIAKTPGLLKENLNICQNGKALCGDQKTCCASKSGGHQCCQYSNAVCCGDQLHCCPEGT 207
H+ P LK ++ C N + C TCC SG CC AVCC D HCCP+G
Sbjct: 351 HLSLPDPQALKRDVP-CDNVSS-CPSSDTCCQLTSGEWGCCPIPEAVCCSDHQHCCPQGY 408
Query: 208 TCDLVNKRCIHQSNEPIEWPVVETIDSAKIETPKYTVERSTLREFMIKIGDKNNCPDGGQ 387
TC + +C S +V ++ + R I +CP G
Sbjct: 409 TC-VAEGQCQRGSE------IVAGLEKMPARRASLSHPRD------IGCDQHTSCPVG-- 453
Query: 388 CAGLQTCCLMYTGHYGCCPFSLSVCCPDLRTCC 486
QTCC G + CC +VCC D + CC
Sbjct: 454 ----QTCCPSLGGSWACCQLPHAVCCEDRQHCC 482
Score = 74.7 bits (182), Expect = 1e-13
Identities = 42/153 (27%), Positives = 55/153 (35%), Gaps = 1/153 (0%)
Frame = +1
Query: 31 VIAKTPGLLKENLNICQNGKALCGDQKTCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTT 210
++ K P L +L A C +C + SG CC + AV CGD HCCP G
Sbjct: 45 LLDKWPTTLSRHLGGPCQVDAHCSAGHSCIFTVSGTSSCCPFPEAVACGDGHHCCPRGFH 104
Query: 211 CDLVNKRCIHQSNEPIEWPVVETIDSAKIETPKYTVERSTLREFMIKIGDKNNCPDGG-Q 387
C + C +S + CPD +
Sbjct: 105 CSADGRSCFQRSGNNSVGAI--------------------------------QCPDSQFE 132
Query: 388 CAGLQTCCLMYTGHYGCCPFSLSVCCPDLRTCC 486
C TCC+M G +GCCP + CC D CC
Sbjct: 133 CPDFSTCCVMVDGSWGCCPMPQASCCEDRVHCC 165
Score = 57.4 bits (137), Expect = 2e-08
Identities = 20/49 (40%), Positives = 25/49 (51%)
Frame = +1
Query: 97 CGDQKTCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCIHQ 243
C D +TCC G CC Y VCC D+ HCCP G C +C+ +
Sbjct: 527 CHDNQTCCRDNRQGWACCPYRQGVCCADRRHCCPAGFRCAARGTKCLRR 575
>sp|P80059|PMD1_LOCMI Pars intercerebralis major peptide D1 (PMP-D1)
Length = 54
Score = 63.5 bits (153), Expect = 2e-10
Identities = 23/47 (48%), Positives = 28/47 (59%)
Frame = +1
Query: 97 CGDQKTCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCI 237
C +TCC + G CC Y VCC D +HCCP GT CD ++RCI
Sbjct: 7 CPGTETCCTTPQGEEGCCPYKEGVCCLDGIHCCPSGTVCDEDHRRCI 53
Score = 43.5 bits (101), Expect = 3e-04
Identities = 16/33 (48%), Positives = 18/33 (54%)
Frame = +1
Query: 388 CAGLQTCCLMYTGHYGCCPFSLSVCCPDLRTCC 486
C G +TCC G GCCP+ VCC D CC
Sbjct: 7 CPGTETCCTTPQGEEGCCPYKEGVCCLDGIHCC 39
>sp|P80930|ENA1_HORSE Antimicrobial peptide eNAP-1
Length = 46
Score = 59.3 bits (142), Expect = 5e-09
Identities = 21/36 (58%), Positives = 23/36 (63%)
Frame = +1
Query: 97 CGDQKTCCASKSGGHQCCQYSNAVCCGDQLHCCPEG 204
C D +TCC + GG CC YS VCC DQ HCCP G
Sbjct: 10 CHDXQTCCRASQGGXACCPYSQGVCCADQRHCCPVG 45
Score = 49.3 bits (116), Expect = 5e-06
Identities = 19/39 (48%), Positives = 21/39 (53%)
Frame = +1
Query: 370 CPDGGQCAGLQTCCLMYTGHYGCCPFSLSVCCPDLRTCC 486
C +G C QTCC G CCP+S VCC D R CC
Sbjct: 4 CGEGHFCHDXQTCCRASQGGXACCPYSQGVCCADQRHCC 42
>sp|P81013|GRN1_CYPCA Granulin-1
Length = 57
Score = 53.5 bits (127), Expect = 2e-07
Identities = 20/48 (41%), Positives = 25/48 (52%)
Frame = +1
Query: 94 LCGDQKTCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCI 237
+C D TCC S G CC +S CC D +HCC G CD + C+
Sbjct: 9 ICPDGTTCCLSPYGVWYCCPFSMGQCCRDGIHCCRHGYHCDSTSTHCL 56
Score = 42.7 bits (99), Expect = 4e-04
Identities = 19/39 (48%), Positives = 21/39 (53%)
Frame = +1
Query: 370 CPDGGQCAGLQTCCLMYTGHYGCCPFSLSVCCPDLRTCC 486
CPDG TCCL G + CCPFS+ CC D CC
Sbjct: 10 CPDG------TTCCLSPYGVWYCCPFSMGQCCRDGIHCC 42
>sp|P81014|GRN2_CYPCA Granulin-2
Length = 57
Score = 50.1 bits (118), Expect = 3e-06
Identities = 19/52 (36%), Positives = 24/52 (46%)
Frame = +1
Query: 82 NGKALCGDQKTCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCI 237
N + C + TCC S G CC + CC D HCC G CD + C+
Sbjct: 5 NARTTCPSRTTCCRSPFGVWYCCPFLMGQCCRDGRHCCRHGYRCDSTSTLCL 56
Score = 39.3 bits (90), Expect = 0.005
Identities = 15/33 (45%), Positives = 17/33 (51%)
Frame = +1
Query: 388 CAGLQTCCLMYTGHYGCCPFSLSVCCPDLRTCC 486
C TCC G + CCPF + CC D R CC
Sbjct: 10 CPSRTTCCRSPFGVWYCCPFLMGQCCRDGRHCC 42
>sp|P81015|GRN3_CYPCA Granulin-3
Length = 57
Score = 45.8 bits (107), Expect = 5e-05
Identities = 18/47 (38%), Positives = 21/47 (44%)
Frame = +1
Query: 97 CGDQKTCCASKSGGHQCCQYSNAVCCGDQLHCCPEGTTCDLVNKRCI 237
C TCC S G CC + CC D HCC G CD + C+
Sbjct: 10 CPSGTTCCRSPFGVWYCCPFLMGQCCRDGRHCCRHGYHCDSTSTLCL 56
Score = 41.2 bits (95), Expect = 0.001
Identities = 17/39 (43%), Positives = 19/39 (48%)
Frame = +1
Query: 370 CPDGGQCAGLQTCCLMYTGHYGCCPFSLSVCCPDLRTCC 486
C G C TCC G + CCPF + CC D R CC
Sbjct: 4 CDAGITCPSGTTCCRSPFGVWYCCPFLMGQCCRDGRHCC 42
>sp|P43297|RD21A_ARATH Cysteine proteinase RD21a precursor (RD21)
Length = 462
Score = 42.7 bits (99), Expect = 4e-04
Identities = 21/59 (35%), Positives = 23/59 (38%), Gaps = 6/59 (10%)
Frame = +1
Query: 97 CGDQKTCCASKSGGHQC-----CQYSNAVCCGDQLHCCP-EGTTCDLVNKRCIHQSNEP 255
C + TCC G C C A CC D CCP E CDL C+ N P
Sbjct: 381 CPESNTCCCLFEYGKYCFAWGCCPLEAATCCDDNYSCCPHEYPVCDLDQGTCLLSKNSP 439
Score = 40.4 bits (93), Expect = 0.002
Identities = 17/43 (39%), Positives = 20/43 (46%), Gaps = 4/43 (9%)
Frame = +1
Query: 370 CPDGGQCAGLQTCCLMYTGHY----GCCPFSLSVCCPDLRTCC 486
CP+ C CCL G Y GCCP + CC D +CC
Sbjct: 381 CPESNTC-----CCLFEYGKYCFAWGCCPLEAATCCDDNYSCC 418
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 59,020,089
Number of Sequences: 369166
Number of extensions: 1252935
Number of successful extensions: 4664
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4024
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4546
length of database: 68,354,980
effective HSP length: 102
effective length of database: 49,512,010
effective search space used: 2921208590
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)