Planaria EST Database

DrC_00370

BLASTX 2.2.13 [Nov-27-2005]

Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= DrC_00370
         (1545 letters)

Database: Non-redundant SwissProt sequences 
           184,735 sequences; 68,354,980 total letters



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

sp|P53634|CATC_HUMAN  Dipeptidyl-peptidase I precursor (DPP-...   466   e-131
sp|P97821|CATC_MOUSE  Dipeptidyl-peptidase I precursor (DPP-...   461   e-129
sp|Q60HG6|CATC_MACFA  Dipeptidyl-peptidase I precursor (DPP-...   454   e-127
sp|P80067|CATC_RAT  Dipeptidyl-peptidase I precursor (DPP-I)...   451   e-126
sp|O97578|CATC_CANFA  Dipeptidyl-peptidase I precursor (DPP-...   444   e-124
sp|Q26563|CATC_SCHMA  Cathepsin C precursor                       425   e-118
sp|P80884|ANAN_ANACO  Ananain precursor                           152   3e-36
sp|P00786|CATH_RAT  Cathepsin H precursor (Cathepsin B3) (Ca...   149   3e-35
sp|P25807|CPR1_CAEEL  Gut-specific cysteine proteinase precu...   145   4e-34
sp|P49935|CATH_MOUSE  Cathepsin H precursor (Cathepsin B3) (...   142   2e-33

>sp|P53634|CATC_HUMAN Dipeptidyl-peptidase I precursor (DPP-I) (DPPI) (Cathepsin C)
            (Cathepsin J) (Dipeptidyl transferase) [Contains:
            Dipeptidyl-peptidase I exclusion domain chain;
            Dipeptidyl-peptidase I heavy chain; Dipeptidyl-peptidase
            I light chain]
          Length = 463

 Score =  466 bits (1200), Expect = e-131
 Identities = 235/469 (50%), Positives = 303/469 (64%), Gaps = 20/469 (4%)
 Frame = +3

Query: 96   AILLAFCLVQLSVS-----DTPANCTYQDVIGKWQVFTGNF----NVSCSTSKLVATKTL 248
            ++LLA  L+ LS       DTPANCTY D++G W    G+     +V+CS       K +
Sbjct: 6    SLLLAALLLLLSGDGAVRCDTPANCTYLDLLGTWVFQVGSSGSQRDVNCSVMGPQEKKVV 65

Query: 249  TLIYP-NWAVDEFGNYGKWTLIYNQGFEVTITNKKYFGFFDYKKINSTYTISYCDRLQPS 425
              +   + A D+ GN G +T+IYNQGFE+ + + K+F FF YK+  S  T +YC+     
Sbjct: 66   VYLQKLDTAYDDLGNSGHFTIIYNQGFEIVLNDYKWFAFFKYKEEGSKVT-TYCNETMTG 124

Query: 426  WFHDVLIRQWQCFKAQRTTTLKE---------KNNVLPHSNIFALTSLRYGSQKRIVDKI 578
            W HDVL R W CF  ++  T  E         KN+   +SN        Y      V  I
Sbjct: 125  WVHDVLGRNWACFTGKKVGTASENVYVNTAHLKNSQEKYSNRL------YKYDHNFVKAI 178

Query: 579  NLENNGWTAKDYPEFHEKTLYEVINMAGGSRSKLERPKPAPITKSILDSVKLIPKSFDWR 758
            N     WTA  Y E+   TL ++I  +GG   K+ RPKPAP+T  I   +  +P S+DWR
Sbjct: 179  NAIQKSWTATTYMEYETLTLGDMIRRSGGHSRKIPRPKPAPLTAEIQQKILHLPTSWDWR 238

Query: 759  NVNGLNYVSPVRNQGGCGSCYSFASAGMLEARYRIRSNNTVRPILSPQDVVECSPYSQGC 938
            NV+G+N+VSPVRNQ  CGSCYSFAS GMLEAR RI +NN+  PILSPQ+VV CS Y+QGC
Sbjct: 239  NVHGINFVSPVRNQASCGSCYSFASMGMLEARIRILTNNSQTPILSPQEVVSCSQYAQGC 298

Query: 939  DGGFPYLIAGKFAEDFGMAQESCNPYKGMNGKCSTTKDCKRYFATNYKYIGGYYGATNEP 1118
            +GGFPYLIAGK+A+DFG+ +E+C PY G +  C   +DC RY+++ Y Y+GG+YG  NE 
Sbjct: 299  EGGFPYLIAGKYAQDFGLVEEACFPYTGTDSPCKMKEDCFRYYSSEYHYVGGFYGGCNEA 358

Query: 1119 LMRMELVKNGPIAVGFEVYDDFMSYSGGVYHHNFGTRKLTTSKFGFNPFELTNHAVLVVG 1298
            LM++ELV +GP+AV FEVYDDF+ Y  G+YHH       T  +  FNPFELTNHAVL+VG
Sbjct: 359  LMKLELVHHGPMAVAFEVYDDFLHYKKGIYHH-------TGLRDPFNPFELTNHAVLLVG 411

Query: 1299 YG-ETSSGEKFWIVKNSWGNGWGENGYFRIRRGNDECGIESLGVASEPI 1442
            YG +++SG  +WIVKNSWG GWGENGYFRIRRG DEC IES+ VA+ PI
Sbjct: 412  YGTDSASGMDYWIVKNSWGTGWGENGYFRIRRGTDECAIESIAVAATPI 460

>sp|P97821|CATC_MOUSE Dipeptidyl-peptidase I precursor (DPP-I) (DPPI) (Cathepsin C)
            (Cathepsin J) (Dipeptidyl transferase) [Contains:
            Dipeptidyl-peptidase I exclusion domain chain;
            Dipeptidyl-peptidase I heavy chain; Dipeptidyl-peptidase
            I light chain]
          Length = 462

 Score =  461 bits (1187), Expect = e-129
 Identities = 232/465 (49%), Positives = 305/465 (65%), Gaps = 13/465 (2%)
 Frame = +3

Query: 87   MMLAILLAFCLVQLSVSDTPANCTYQDVIGKWQVFTG----NFNVSCSTSKLVATKTLTL 254
            ++L +LL  C V+   SDTPANCTY D++G W    G      +++CS  +    K +  
Sbjct: 11   VLLLVLLGVCTVR---SDTPANCTYPDLLGTWVFQVGPRSSRSDINCSVMEATEEKVVVH 67

Query: 255  IYP-NWAVDEFGNYGKWTLIYNQGFEVTITNKKYFGFFDYKKINSTYTISYCDRLQPSWF 431
            +   + A DE GN G +TLIYNQGFE+ + + K+F FF Y+    T  ISYC      W 
Sbjct: 68   LKKLDTAYDELGNSGHFTLIYNQGFEIVLNDYKWFAFFKYEVRGHT-AISYCHETMTGWV 126

Query: 432  HDVLIRQWQCFKAQRTTTLKEKNNVLPHSNIFALTSLR-------YGSQKRIVDKINLEN 590
            HDVL R W CF  ++  +  EK N+    N   L  L+       Y      V  IN   
Sbjct: 127  HDVLGRNWACFVGKKVESHIEKVNM----NAAHLGGLQERYSERLYTHNHNFVKAINTVQ 182

Query: 591  NGWTAKDYPEFHEKTLYEVINMAGGSRSKLERPKPAPITKSILDSVKLIPKSFDWRNVNG 770
              WTA  Y E+ + +L ++I  +G S+ ++ RPKPAP+T  I   +  +P+S+DWRNV G
Sbjct: 183  KSWTATAYKEYEKMSLRDLIRRSGHSQ-RIPRPKPAPMTDEIQQQILNLPESWDWRNVQG 241

Query: 771  LNYVSPVRNQGGCGSCYSFASAGMLEARYRIRSNNTVRPILSPQDVVECSPYSQGCDGGF 950
            +NYVSPVRNQ  CGSCYSFAS GMLEAR RI +NN+  PILSPQ+VV CSPY+QGCDGGF
Sbjct: 242  VNYVSPVRNQESCGSCYSFASMGMLEARIRILTNNSQTPILSPQEVVSCSPYAQGCDGGF 301

Query: 951  PYLIAGKFAEDFGMAQESCNPYKGMNGKCSTTKDCKRYFATNYKYIGGYYGATNEPLMRM 1130
            PYLIAGK+A+DFG+ +ESC PY   +  C   ++C RY++++Y Y+GG+YG  NE LM++
Sbjct: 302  PYLIAGKYAQDFGVVEESCFPYTAKDSPCKpreNCLRYYSSDYYYVGGFYGGCNEALMKL 361

Query: 1131 ELVKNGPIAVGFEVYDDFMSYSGGVYHHNFGTRKLTTSKFGFNPFELTNHAVLVVGYG-E 1307
            ELVK+GP+AV FEV+DDF+ Y  G+YHH       T     FNPFELTNHAVL+VGYG +
Sbjct: 362  ELVKHGPMAVAFEVHDDFLHYHSGIYHH-------TGLSDPFNPFELTNHAVLLVGYGRD 414

Query: 1308 TSSGEKFWIVKNSWGNGWGENGYFRIRRGNDECGIESLGVASEPI 1442
              +G ++WI+KNSWG+ WGE+GYFRIRRG DEC IES+ VA+ PI
Sbjct: 415  PVTGIEYWIIKNSWGSNWGESGYFRIRRGTDECAIESIAVAAIPI 459

>sp|Q60HG6|CATC_MACFA Dipeptidyl-peptidase I precursor (DPP-I) (DPPI) (Cathepsin C)
            (Cathepsin J) (Dipeptidyl transferase) [Contains:
            Dipeptidyl-peptidase I exclusion domain chain;
            Dipeptidyl-peptidase I heavy chain; Dipeptidyl-peptidase
            I light chain]
          Length = 463

 Score =  454 bits (1169), Expect = e-127
 Identities = 231/469 (49%), Positives = 297/469 (63%), Gaps = 20/469 (4%)
 Frame = +3

Query: 96   AILLAFCLVQLSVS-----DTPANCTYQDVIGKWQVFTGNF----NVSCSTSKLVATKTL 248
            A LLA  L+ LS       DTPANCTY D++G W    G+     +V+CS       K +
Sbjct: 6    ASLLAALLLLLSGDRAVRCDTPANCTYLDLLGTWVFQVGSSGSLRDVNCSVMGPPEKKVV 65

Query: 249  TLIYP-NWAVDEFGNYGKWTLIYNQGFEVTITNKKYFGFFDYKKINSTYTISYCDRLQPS 425
              +   + A D+ GN G +T+IYNQGFE+ + + K+F FF YK+     TI YC+     
Sbjct: 66   VHLQKLDTAYDDLGNSGHFTIIYNQGFEIVLNDYKWFAFFKYKEEGIKVTI-YCNETMTG 124

Query: 426  WFHDVLIRQWQCFKAQRTTTLKE---------KNNVLPHSNIFALTSLRYGSQKRIVDKI 578
            W HDVL R W CF  ++  T  E         KN+   +SN        Y      V  I
Sbjct: 125  WVHDVLGRNWACFTGKKVGTASENVYVNTAHLKNSQEKYSNRL------YKYDHNFVKAI 178

Query: 579  NLENNGWTAKDYPEFHEKTLYEVINMAGGSRSKLERPKPAPITKSILDSVKLIPKSFDWR 758
            N     WTA  Y E+   TL ++I  +GG   K+ RPKP P+T  I   +  +P S+DWR
Sbjct: 179  NAIQKSWTATTYMEYETLTLGDMIKRSGGHSRKIPRPKPTPLTAEIQQKILHLPTSWDWR 238

Query: 759  NVNGLNYVSPVRNQGGCGSCYSFASAGMLEARYRIRSNNTVRPILSPQDVVECSPYSQGC 938
            NV+G+N+VSPVRNQ  CGSCYSFAS GMLEAR RI +NN+  PILS Q+VV CS Y+QGC
Sbjct: 239  NVHGINFVSPVRNQASCGSCYSFASVGMLEARIRILTNNSQTPILSSQEVVSCSQYAQGC 298

Query: 939  DGGFPYLIAGKFAEDFGMAQESCNPYKGMNGKCSTTKDCKRYFATNYKYIGGYYGATNEP 1118
            +GGFPYL AGK+A+DFG+ +E+C PY G +  C   +DC RY+++ Y Y+GG+YG  NE 
Sbjct: 299  EGGFPYLTAGKYAQDFGLVEEACFPYTGTDSPCKMKEDCFRYYSSEYHYVGGFYGGCNEA 358

Query: 1119 LMRMELVKNGPIAVGFEVYDDFMSYSGGVYHHNFGTRKLTTSKFGFNPFELTNHAVLVVG 1298
            LM++ELV +GP+AV FEVYDDF+ Y  G+YHH       T  +  FNPFELTNHAVL+VG
Sbjct: 359  LMKLELVYHGPLAVAFEVYDDFLHYQNGIYHH-------TGLRDPFNPFELTNHAVLLVG 411

Query: 1299 YG-ETSSGEKFWIVKNSWGNGWGENGYFRIRRGNDECGIESLGVASEPI 1442
            YG +++SG  +WIVKNSWG  WGE+GYFRIRRG DEC IES+ VA+ PI
Sbjct: 412  YGTDSASGMDYWIVKNSWGTSWGEDGYFRIRRGTDECAIESIAVAATPI 460

>sp|P80067|CATC_RAT Dipeptidyl-peptidase I precursor (DPP-I) (DPPI) (Cathepsin C)
            (Cathepsin J) (Dipeptidyl transferase) [Contains:
            Dipeptidyl-peptidase I exclusion domain chain;
            Dipeptidyl-peptidase I heavy chain; Dipeptidyl-peptidase
            I light chain]
          Length = 462

 Score =  451 bits (1160), Expect = e-126
 Identities = 227/464 (48%), Positives = 298/464 (64%), Gaps = 13/464 (2%)
 Frame = +3

Query: 90   MLAILLAFCLVQLSVSDTPANCTYQDVIGKWQVFTG----NFNVSCSTSKLVATKTLTLI 257
            +L +LL  C V    SDTPANCTY D++G W    G      +++CS  +    K +  +
Sbjct: 12   LLLVLLGVCTVS---SDTPANCTYPDLLGTWVFQVGPRHPRSHINCSVMEPTEEKVVIHL 68

Query: 258  YP-NWAVDEFGNYGKWTLIYNQGFEVTITNKKYFGFFDYKKINSTYTISYCDRLQPSWFH 434
               + A DE GN G +TLIYNQGFE+ + + K+F FF Y+ +  +  ISYC      W H
Sbjct: 69   KKLDTAYDEVGNSGYFTLIYNQGFEIVLNDYKWFAFFKYE-VKGSRAISYCHETMTGWVH 127

Query: 435  DVLIRQWQCFKAQRTTTLKEKNNVLPHSNIFALTSLR-------YGSQKRIVDKINLENN 593
            D L R W CF  ++     EK  V    N+  L  L+       Y      V  IN    
Sbjct: 128  DYLGRNWACFVGKKMANHSEKVYV----NVAHLGGLQEKYSERLYSHHHNFVKAINSVQK 183

Query: 594  GWTAKDYPEFHEKTLYEVINMAGGSRSKLERPKPAPITKSILDSVKLIPKSFDWRNVNGL 773
             WTA  Y  + + ++ ++I  +G S  ++ RPKPAPIT  I   +  +P+S+DWRNV G+
Sbjct: 184  SWTATTYRRYEKLSIRDLIRRSGHS-GRILRPKPAPITDEIQQQILSLPESWDWRNVRGI 242

Query: 774  NYVSPVRNQGGCGSCYSFASAGMLEARYRIRSNNTVRPILSPQDVVECSPYSQGCDGGFP 953
            N+VSPVRNQ  CGSCYSFAS GMLEAR RI +NN+  PILSPQ+VV CSPY+QGCDGGFP
Sbjct: 243  NFVSPVRNQESCGSCYSFASIGMLEARIRILTNNSQTPILSPQEVVSCSPYAQGCDGGFP 302

Query: 954  YLIAGKFAEDFGMAQESCNPYKGMNGKCSTTKDCKRYFATNYKYIGGYYGATNEPLMRME 1133
            YLIAGK+A+DFG+ +E+C PY   +  C   ++C RY+++ Y Y+GG+YG  NE LM++E
Sbjct: 303  YLIAGKYAQDFGVVEENCFPYTATDAPCKPKENCLRYYSSEYYYVGGFYGGCNEALMKLE 362

Query: 1134 LVKNGPIAVGFEVYDDFMSYSGGVYHHNFGTRKLTTSKFGFNPFELTNHAVLVVGYG-ET 1310
            LVK+GP+AV FEV+DDF+ Y  G+YHH       T     FNPFELTNHAVL+VGYG + 
Sbjct: 363  LVKHGPMAVAFEVHDDFLHYHSGIYHH-------TGLSDPFNPFELTNHAVLLVGYGKDP 415

Query: 1311 SSGEKFWIVKNSWGNGWGENGYFRIRRGNDECGIESLGVASEPI 1442
             +G  +WIVKNSWG+ WGE+GYFRIRRG DEC IES+ +A+ PI
Sbjct: 416  VTGLDYWIVKNSWGSQWGESGYFRIRRGTDECAIESIAMAAIPI 459

>sp|O97578|CATC_CANFA Dipeptidyl-peptidase I precursor (DPP-I) (DPPI) (Cathepsin C)
            (Cathepsin J) (Dipeptidyl transferase) [Contains:
            Dipeptidyl-peptidase I exclusion domain chain;
            Dipeptidyl-peptidase I heavy chain 1;
            Dipeptidyl-peptidase I heavy chain 2;
            Dipeptidyl-peptidase I heavy chain 3;
            Dipeptidyl-peptidase I heavy chain 4;
            Dipeptidyl-peptidase I light chain]
          Length = 435

 Score =  444 bits (1142), Expect = e-124
 Identities = 225/448 (50%), Positives = 290/448 (64%), Gaps = 13/448 (2%)
 Frame = +3

Query: 138  DTPANCTYQDVIGKWQVF----TGNFNVSCSTSKLVATKTLTLIYP-NWAVDEFGNYGKW 302
            DTPANCT+ +++G W VF     G+ +V+CS       K +  +   + A D FGN G +
Sbjct: 1    DTPANCTHPELLGTW-VFQVGPAGSRSVNCSVMGPPEKKVVVHLEKLDTAYDNFGNTGHF 59

Query: 303  TLIYNQGFEVTITNKKYFGFFDYKKINSTYTISYCDRLQPSWFHDVLIRQWQCFKAQRTT 482
            T+IYNQGFE+ + + K+F FF YK+     T SYC+     W HDVL R W CF   +  
Sbjct: 60   TIIYNQGFEIVLNDYKWFAFFKYKEEGHKVT-SYCNETMTGWVHDVLGRNWACFTGTKMG 118

Query: 483  TLKEKNNV-------LPHSNIFALTSLRYGSQKRIVDKINLENNGWTAKDYPEFHEKTLY 641
            T  EK  V       L  +N   L    Y      V  IN     WTA  Y E+   TL 
Sbjct: 119  TTSEKAKVNTKHIERLQENNSNRLYKYNY----EFVKAINTIQKSWTATRYIEYETLTLR 174

Query: 642  EVINMAGGSRSKLERPKPAPITKSILDSVKLIPKSFDWRNVNGLNYVSPVRNQGGCGSCY 821
            +++   GG   K+ RPKP P+T  I + +  +P S+DWRNV G N+VSPVRNQ  CGSCY
Sbjct: 175  DMMTRVGGR--KIPRPKPTPLTAEIHEEISRLPTSWDWRNVRGTNFVSPVRNQASCGSCY 232

Query: 822  SFASAGMLEARYRIRSNNTVRPILSPQDVVECSPYSQGCDGGFPYLIAGKFAEDFGMAQE 1001
            +FAS  MLEAR RI +NNT  PILSPQ++V CS Y+QGC+GGFPYLIAGK+A+DFG+ +E
Sbjct: 233  AFASTAMLEARIRILTNNTQTPILSPQEIVSCSQYAQGCEGGFPYLIAGKYAQDFGLVEE 292

Query: 1002 SCNPYKGMNGKCSTTKDCKRYFATNYKYIGGYYGATNEPLMRMELVKNGPIAVGFEVYDD 1181
            +C PY G +  C    DC RY+++ Y Y+GG+YGA NE LM++ELV++GP+AV FEVYDD
Sbjct: 293  ACFPYAGSDSPCK-PNDCFRYYSSEYYYVGGFYGACNEALMKLELVRHGPMAVAFEVYDD 351

Query: 1182 FMSYSGGVYHHNFGTRKLTTSKFGFNPFELTNHAVLVVGYG-ETSSGEKFWIVKNSWGNG 1358
            F  Y  G+Y+H       T  +  FNPFELTNHAVL+VGYG +++SG  +WIVKNSWG+ 
Sbjct: 352  FFHYQKGIYYH-------TGLRDPFNPFELTNHAVLLVGYGTDSASGMDYWIVKNSWGSR 404

Query: 1359 WGENGYFRIRRGNDECGIESLGVASEPI 1442
            WGE+GYFRIRRG DEC IES+ VA+ PI
Sbjct: 405  WGEDGYFRIRRGTDECAIESIAVAATPI 432

>sp|Q26563|CATC_SCHMA Cathepsin C precursor
          Length = 454

 Score =  425 bits (1093), Expect = e-118
 Identities = 222/459 (48%), Positives = 291/459 (63%), Gaps = 10/459 (2%)
 Frame = +3

Query: 99   ILLAFCLVQLSVSDTPANCTYQDVIGKWQVFTGNFNVSCSTSKLVATKT--LTLIYPNWA 272
            IL+    ++ + +DTPANCTY+D  G+W+   G++   C   KL + ++  ++L+YP+ A
Sbjct: 8    ILIILACLRFTCADTPANCTYEDAHGRWKFHIGDYQSKCP-EKLNSKQSVVISLLYPDIA 66

Query: 273  VDEFGNYGKWTLIYNQGFEVTITNKKYFGFFDYKKINSTYTISYCDRLQPSWFHDVLIRQ 452
            +DEFGN G WTLIYNQGFEVTI ++K+   F YK  N  +    C +  P W HD LI  
Sbjct: 67   IDEFGNRGHWTLIYNQGFEVTINHRKWLVIFAYKS-NGEFN---CHKSMPMWTHDTLIDS 122

Query: 453  WQCFKAQRTTTLKEKNNVLPHSNIFALTSLRYGSQKRIVDKINLENNGWTAKDYPEFHEK 632
                  +     K   N L  S  F  T   Y      V KIN     W  + YPE  + 
Sbjct: 123  GSVCSGKIGVHDKFHINKLFGSKSFGRTL--YHINPSFVGKINAHQKSWRGEIYPELSKY 180

Query: 633  TLYEVINMAGGSRSKLERP----KPAPITKSILDSVKLIPKSFDWRNV--NGLNYVSPVR 794
            T+ E+ N AGG +S + RP    +  P +K ++     +P  FDW +      + V+P+R
Sbjct: 181  TIDELRNRAGGVKSMVTRPSVLNRKTP-SKELISLTGNLPLEFDWTSPPDGSRSPVTPIR 239

Query: 795  NQGGCGSCYSFASAGMLEARYRIRSNNTVRPILSPQDVVECSPYSQGCDGGFPYLIAGKF 974
            NQG CGSCY+  SA  LEAR R+ SN + +PILSPQ VV+CSPYS+GC+GGFP+LIAGK+
Sbjct: 240  NQGICGSCYASPSAAALEARIRLVSNFSEQPILSPQTVVDCSPYSEGCNGGFPFLIAGKY 299

Query: 975  AEDFGMAQESCNPYKGMN-GKCSTTKDCKRYFATNYKYIGGYYGATNEPLMRMELVKNGP 1151
             EDFG+ Q+   PY G + GKC+ +K+C RY+ T+Y YIGGYYGATNE LM++EL+ NGP
Sbjct: 300  GEDFGLPQKIVIPYTGEDTGKCTVSKNCTRYYTTDYSYIGGYYGATNEKLMQLELISNGP 359

Query: 1152 IAVGFEVYDDFMSYSGGVYHHNFGTRKLTTSKFGFNPFELTNHAVLVVGYG-ETSSGEKF 1328
              VGFEVY+DF  Y  G+YHH      + T  + FNPFELTNHAVL+VGYG +  SGE +
Sbjct: 360  FPVGFEVYEDFQFYKEGIYHHT----TVQTDHYNFNPFELTNHAVLLVGYGVDKLSGEPY 415

Query: 1329 WIVKNSWGNGWGENGYFRIRRGNDECGIESLGVASEPIL 1445
            W VKNSWG  WGE GYFRI RG DECG+ESLGV  +P+L
Sbjct: 416  WKVKNSWGVEWGEQGYFRILRGTDECGVESLGVRFDPVL 454

>sp|P80884|ANAN_ANACO Ananain precursor
          Length = 345

 Score =  152 bits (383), Expect = 3e-36
 Identities = 104/346 (30%), Positives = 161/346 (46%)
 Frame = +3

Query: 405  CDRLQPSWFHDVLIRQWQCFKAQRTTTLKEKNNVLPHSNIFALTSLRYGSQKRIVDKINL 584
            CD  +PS   D +++Q++ + A+     K+ +  +    IF        +    ++  N 
Sbjct: 26   CD--EPS---DPMMKQFEEWMAEYGRVYKDNDEKMLRFQIFK-------NNVNHIETFNN 73

Query: 585  ENNGWTAKDYPEFHEKTLYEVINMAGGSRSKLERPKPAPITKSILDSVKLIPKSFDWRNV 764
             N         +F + T  E +    G    L   +   ++   +D +  +P+S DWR+ 
Sbjct: 74   RNGNSYTLGINQFTDMTNNEFVAQYTGLSLPLNIKREPVVSFDDVD-ISSVPQSIDWRDS 132

Query: 765  NGLNYVSPVRNQGGCGSCYSFASAGMLEARYRIRSNNTVRPILSPQDVVECSPYSQGCDG 944
                 V+ V+NQG CGSC++FAS   +E+ Y+I+  N V   LS Q V++C+  S GC G
Sbjct: 133  GA---VTSVKNQGRCGSCWAFASIATVESIYKIKRGNLVS--LSEQQVLDCA-VSYGCKG 186

Query: 945  GFPYLIAGKFAEDFGMAQESCNPYKGMNGKCSTTKDCKRYFATNYKYIGGYYGATNEPLM 1124
            G+          + G+A  +  PYK   G C T       + T Y Y+       N    
Sbjct: 187  GWINKAYSFIISNKGVASAAIYPYKAAKGTCKTNGVPNSAYITRYTYV-----QRNNERN 241

Query: 1125 RMELVKNGPIAVGFEVYDDFMSYSGGVYHHNFGTRKLTTSKFGFNPFELTNHAVLVVGYG 1304
             M  V N PIA   +   +F  Y  GV+    GTR               NHA++++GYG
Sbjct: 242  MMYAVSNQPIAAALDASGNFQHYKRGVFTGPCGTR--------------LNHAIVIIGYG 287

Query: 1305 ETSSGEKFWIVKNSWGNGWGENGYFRIRRGNDECGIESLGVASEPI 1442
            + SSG+KFWIV+NSWG GWGE GY R+ R +        G+A +P+
Sbjct: 288  QDSSGKKFWIVRNSWGAGWGEGGYIRLAR-DVSSSFGLCGIAMDPL 332

>sp|P00786|CATH_RAT Cathepsin H precursor (Cathepsin B3) (Cathepsin BA) [Contains:
            Cathepsin H mini chain; Cathepsin H heavy chain;
            Cathepsin H light chain]
          Length = 333

 Score =  149 bits (375), Expect = 3e-35
 Identities = 98/255 (38%), Positives = 127/255 (49%), Gaps = 3/255 (1%)
 Frame = +3

Query: 687  PKPAPITKS-ILDSVKLIPKSFDWRNVNGLNYVSPVRNQGGCGSCYSFASAGMLEARYRI 863
            P+    TKS  L      P S DWR     N VSPV+NQG CGSC++F++ G LE+   I
Sbjct: 97   PQNCSATKSNYLRGTGPYPSSMDWRKKG--NVVSPVKNQGACGSCWTFSTTGALESAVAI 154

Query: 864  RSNNTVRPILSPQDVVECSPY--SQGCDGGFPYLIAGKFAEDFGMAQESCNPYKGMNGKC 1037
             S   +   L+ Q +V+C+    + GC GG P         + G+  E   PY G NG+C
Sbjct: 155  ASGKMMT--LAEQQLVDCAQNFNNHGCQGGLPSQAFEYILYNKGIMGEDSYPYIGKNGQC 212

Query: 1038 STTKDCKRYFATNYKYIGGYYGATNEPLMRMELVKNGPIAVGFEVYDDFMSYSGGVYHHN 1217
                +    F  N   I       +E  M   +    P++  FEV +DFM Y  GVY  N
Sbjct: 213  KFNPEKAVAFVKNVVNIT----LNDEAAMVEAVALYNPVSFAFEVTEDFMMYKSGVYSSN 268

Query: 1218 FGTRKLTTSKFGFNPFELTNHAVLVVGYGETSSGEKFWIVKNSWGNGWGENGYFRIRRGN 1397
               +  T  K         NHAVL VGYGE  +G  +WIVKNSWG+ WG NGYF I RG 
Sbjct: 269  SCHK--TPDK--------VNHAVLAVGYGE-QNGLLYWIVKNSWGSNWGNNGYFLIERGK 317

Query: 1398 DECGIESLGVASEPI 1442
            + CG+ +   AS PI
Sbjct: 318  NMCGLAA--CASYPI 330

>sp|P25807|CPR1_CAEEL Gut-specific cysteine proteinase precursor
          Length = 329

 Score =  145 bits (365), Expect = 4e-34
 Identities = 88/257 (34%), Positives = 134/257 (52%), Gaps = 23/257 (8%)
 Frame = +3

Query: 735  IPKSFDWRNV-NGLNYVSPVRNQGGCGSCYSFASAGMLEARYRIRSNNTVRPILSPQDVV 911
            +P +FD R   +    +  +R+Q  CGSC++F +A M+  R  I +    +PI+SP D++
Sbjct: 85   VPATFDSRTQWSECKSIKLIRDQATCGSCWAFGAAEMISDRTCIETKGAQQPIISPDDLL 144

Query: 912  EC--SPYSQGCDGGFPYLIAGKFAEDFGMAQ------ESCNPYK---GMNGKCSTTK--- 1049
             C  S    GC+GG+P + A ++ +  G+          C PY      +G C  +K   
Sbjct: 145  SCCGSSCGNGCEGGYP-IQALRWWDSKGVVTGGDYHGAGCKPYPIAPCTSGNCPESKTPS 203

Query: 1050 ---DCKRYFATNY---KYIG--GYYGATNEPLMRMELVKNGPIAVGFEVYDDFMSYSGGV 1205
                C+  ++T Y   K+ G   Y    N   ++ E+  NGP+   F VY+DF  Y  GV
Sbjct: 204  CSMSCQSGYSTAYAKDKHFGVSAYAVPKNAASIQAEIYANGPVEAAFSVYEDFYKYKSGV 263

Query: 1206 YHHNFGTRKLTTSKFGFNPFELTNHAVLVVGYGETSSGEKFWIVKNSWGNGWGENGYFRI 1385
            Y H       T  K+      L  HA+ ++G+G T SG  +W+V NSWG  WGE+G+F+I
Sbjct: 264  YKH-------TAGKY------LGGHAIKIIGWG-TESGSPYWLVANSWGVNWGESGFFKI 309

Query: 1386 RRGNDECGIESLGVASE 1436
             RG+D+CGIES  VA +
Sbjct: 310  YRGDDQCGIESAVVAGK 326

>sp|P49935|CATH_MOUSE Cathepsin H precursor (Cathepsin B3) (Cathepsin BA) [Contains:
            Cathepsin H mini chain; Cathepsin H heavy chain;
            Cathepsin H light chain]
          Length = 333

 Score =  142 bits (359), Expect = 2e-33
 Identities = 94/255 (36%), Positives = 125/255 (49%), Gaps = 3/255 (1%)
 Frame = +3

Query: 687  PKPAPITKS-ILDSVKLIPKSFDWRNVNGLNYVSPVRNQGGCGSCYSFASAGMLEARYRI 863
            P+    TKS  L      P S DWR     N VSPV+NQG C SC++F++ G LE+   I
Sbjct: 97   PQNCSATKSNYLRGTGPYPSSMDWRKKG--NVVSPVKNQGACASCWTFSTTGALESAVAI 154

Query: 864  RSNNTVRPILSPQDVVECSPY--SQGCDGGFPYLIAGKFAEDFGMAQESCNPYKGMNGKC 1037
             S   +   L+ Q +V+C+    + GC GG P         + G+ +E   PY G +  C
Sbjct: 155  ASGKMLS--LAEQQLVDCAQAFNNHGCKGGLPSQAFEYILYNKGIMEEDSYPYIGKDSSC 212

Query: 1038 STTKDCKRYFATNYKYIGGYYGATNEPLMRMELVKNGPIAVGFEVYDDFMSYSGGVYHHN 1217
                     F  N   I       +E  M   +    P++  FEV +DF+ Y  GVY   
Sbjct: 213  RFNPQKAVAFVKNVVNIT----LNDEAAMVEAVALYNPVSFAFEVTEDFLMYKSGVY--- 265

Query: 1218 FGTRKLTTSKFGFNPFELTNHAVLVVGYGETSSGEKFWIVKNSWGNGWGENGYFRIRRGN 1397
                   +SK      +  NHAVL VGYGE  +G  +WIVKNSWG+ WGENGYF I RG 
Sbjct: 266  -------SSKSCHKTPDKVNHAVLAVGYGE-QNGLLYWIVKNSWGSQWGENGYFLIERGK 317

Query: 1398 DECGIESLGVASEPI 1442
            + CG+ +   AS PI
Sbjct: 318  NMCGLAA--CASYPI 330

  Database: Non-redundant SwissProt sequences
    Posted date:  Dec 6, 2005  7:40 AM
  Number of letters in database: 68,354,980
  Number of sequences in database:  184,735
  
  Database: swissprot.01
    Posted date:  Dec 6, 2005  8:18 AM
  Number of letters in database: 66,202,850
  Number of sequences in database:  184,431
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 183,410,274
Number of Sequences: 369166
Number of extensions: 4046476
Number of successful extensions: 10738
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 9509
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 10182
length of database: 68,354,980
effective HSP length: 115
effective length of database: 47,110,455
effective search space used: 18797071545
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)

Cluster detail

DrC_00370

  1. Dr_sW_022_H21
  2. Dr_sW_009_N21
  3. Dr_sW_014_K04
  4. Dr_sW_015_I18
  5. Dr_sW_011_N21
  6. Dr_sW_019_B13
  7. Dr_sW_001_L16
  8. Dr_sW_022_C11
  9. Dr_sW_019_A11
  10. Dr_sW_017_P21
  11. Dr_sW_009_E19
  12. Dr_sW_010_C14
  13. Dr_sW_002_L02
  14. Dr_sW_020_L23
  15. Dr_sW_009_E09
  16. Dr_sW_014_G06
  17. Dr_sW_009_K11
  18. Dr_sW_024_B07
  19. Dr_sW_010_G21
  20. Dr_sW_001_O06
  21. Dr_sW_013_N14
  22. Dr_sW_018_N11
  23. Dr_sW_019_I24
  24. Dr_sW_022_C06
  25. Dr_sW_008_M21
  26. Dr_sW_004_G08
  27. Dr_sW_026_E18