Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_004_G08
(389 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P53634|CATC_HUMAN Dipeptidyl-peptidase I precursor (DPP-... 147 7e-36
sp|Q60HG6|CATC_MACFA Dipeptidyl-peptidase I precursor (DPP-... 144 8e-35
sp|Q26563|CATC_SCHMA Cathepsin C precursor 143 1e-34
sp|O97578|CATC_CANFA Dipeptidyl-peptidase I precursor (DPP-... 140 7e-34
sp|P97821|CATC_MOUSE Dipeptidyl-peptidase I precursor (DPP-... 139 2e-33
sp|P80067|CATC_RAT Dipeptidyl-peptidase I precursor (DPP-I)... 137 8e-33
sp|P25807|CPR1_CAEEL Gut-specific cysteine proteinase precu... 97 1e-20
sp|P43510|CPR6_CAEEL Cathepsin B-like cysteine proteinase 6... 94 7e-20
sp|P43508|CPR4_CAEEL Cathepsin B-like cysteine proteinase 4... 94 1e-19
sp|P43509|CPR5_CAEEL Cathepsin B-like cysteine proteinase 5... 93 2e-19
>sp|P53634|CATC_HUMAN Dipeptidyl-peptidase I precursor (DPP-I) (DPPI) (Cathepsin C)
(Cathepsin J) (Dipeptidyl transferase) [Contains:
Dipeptidyl-peptidase I exclusion domain chain;
Dipeptidyl-peptidase I heavy chain; Dipeptidyl-peptidase
I light chain]
Length = 463
Score = 147 bits (371), Expect = 7e-36
Identities = 69/107 (64%), Positives = 83/107 (77%), Gaps = 1/107 (0%)
Frame = +3
Query: 3 RMELVKNGPIAVGFEVYDDFMSYSGGVYHHNFGTRKLTTSKFGFNPFELTNHAVLVVGYG 182
++ELV +GP+AV FEVYDDF+ Y G+YHH T + FNPFELTNHAVL+VGYG
Sbjct: 361 KLELVHHGPMAVAFEVYDDFLHYKKGIYHH-------TGLRDPFNPFELTNHAVLLVGYG 413
Query: 183 -ETSSGEKFWIVKNSWGNGWGENGYFRIRRGNDECGIESLGVASEPI 320
+++SG +WIVKNSWG GWGENGYFRIRRG DEC IES+ VA+ PI
Sbjct: 414 TDSASGMDYWIVKNSWGTGWGENGYFRIRRGTDECAIESIAVAATPI 460
>sp|Q60HG6|CATC_MACFA Dipeptidyl-peptidase I precursor (DPP-I) (DPPI) (Cathepsin C)
(Cathepsin J) (Dipeptidyl transferase) [Contains:
Dipeptidyl-peptidase I exclusion domain chain;
Dipeptidyl-peptidase I heavy chain; Dipeptidyl-peptidase
I light chain]
Length = 463
Score = 144 bits (362), Expect = 8e-35
Identities = 67/107 (62%), Positives = 82/107 (76%), Gaps = 1/107 (0%)
Frame = +3
Query: 3 RMELVKNGPIAVGFEVYDDFMSYSGGVYHHNFGTRKLTTSKFGFNPFELTNHAVLVVGYG 182
++ELV +GP+AV FEVYDDF+ Y G+YHH T + FNPFELTNHAVL+VGYG
Sbjct: 361 KLELVYHGPLAVAFEVYDDFLHYQNGIYHH-------TGLRDPFNPFELTNHAVLLVGYG 413
Query: 183 -ETSSGEKFWIVKNSWGNGWGENGYFRIRRGNDECGIESLGVASEPI 320
+++SG +WIVKNSWG WGE+GYFRIRRG DEC IES+ VA+ PI
Sbjct: 414 TDSASGMDYWIVKNSWGTSWGEDGYFRIRRGTDECAIESIAVAATPI 460
>sp|Q26563|CATC_SCHMA Cathepsin C precursor
Length = 454
Score = 143 bits (361), Expect = 1e-34
Identities = 66/108 (61%), Positives = 79/108 (73%), Gaps = 1/108 (0%)
Frame = +3
Query: 3 RMELVKNGPIAVGFEVYDDFMSYSGGVYHHNFGTRKLTTSKFGFNPFELTNHAVLVVGYG 182
++EL+ NGP VGFEVY+DF Y G+YHH + T + FNPFELTNHAVL+VGYG
Sbjct: 351 QLELISNGPFPVGFEVYEDFQFYKEGIYHHT----TVQTDHYNFNPFELTNHAVLLVGYG 406
Query: 183 -ETSSGEKFWIVKNSWGNGWGENGYFRIRRGNDECGIESLGVASEPIL 323
+ SGE +W VKNSWG WGE GYFRI RG DECG+ESLGV +P+L
Sbjct: 407 VDKLSGEPYWKVKNSWGVEWGEQGYFRILRGTDECGVESLGVRFDPVL 454
>sp|O97578|CATC_CANFA Dipeptidyl-peptidase I precursor (DPP-I) (DPPI) (Cathepsin C)
(Cathepsin J) (Dipeptidyl transferase) [Contains:
Dipeptidyl-peptidase I exclusion domain chain;
Dipeptidyl-peptidase I heavy chain 1;
Dipeptidyl-peptidase I heavy chain 2;
Dipeptidyl-peptidase I heavy chain 3;
Dipeptidyl-peptidase I heavy chain 4;
Dipeptidyl-peptidase I light chain]
Length = 435
Score = 140 bits (354), Expect = 7e-34
Identities = 66/107 (61%), Positives = 83/107 (77%), Gaps = 1/107 (0%)
Frame = +3
Query: 3 RMELVKNGPIAVGFEVYDDFMSYSGGVYHHNFGTRKLTTSKFGFNPFELTNHAVLVVGYG 182
++ELV++GP+AV FEVYDDF Y G+Y+H T + FNPFELTNHAVL+VGYG
Sbjct: 333 KLELVRHGPMAVAFEVYDDFFHYQKGIYYH-------TGLRDPFNPFELTNHAVLLVGYG 385
Query: 183 -ETSSGEKFWIVKNSWGNGWGENGYFRIRRGNDECGIESLGVASEPI 320
+++SG +WIVKNSWG+ WGE+GYFRIRRG DEC IES+ VA+ PI
Sbjct: 386 TDSASGMDYWIVKNSWGSRWGEDGYFRIRRGTDECAIESIAVAATPI 432
>sp|P97821|CATC_MOUSE Dipeptidyl-peptidase I precursor (DPP-I) (DPPI) (Cathepsin C)
(Cathepsin J) (Dipeptidyl transferase) [Contains:
Dipeptidyl-peptidase I exclusion domain chain;
Dipeptidyl-peptidase I heavy chain; Dipeptidyl-peptidase
I light chain]
Length = 462
Score = 139 bits (351), Expect = 2e-33
Identities = 65/107 (60%), Positives = 82/107 (76%), Gaps = 1/107 (0%)
Frame = +3
Query: 3 RMELVKNGPIAVGFEVYDDFMSYSGGVYHHNFGTRKLTTSKFGFNPFELTNHAVLVVGYG 182
++ELVK+GP+AV FEV+DDF+ Y G+YHH T FNPFELTNHAVL+VGYG
Sbjct: 360 KLELVKHGPMAVAFEVHDDFLHYHSGIYHH-------TGLSDPFNPFELTNHAVLLVGYG 412
Query: 183 -ETSSGEKFWIVKNSWGNGWGENGYFRIRRGNDECGIESLGVASEPI 320
+ +G ++WI+KNSWG+ WGE+GYFRIRRG DEC IES+ VA+ PI
Sbjct: 413 RDPVTGIEYWIIKNSWGSNWGESGYFRIRRGTDECAIESIAVAAIPI 459
>sp|P80067|CATC_RAT Dipeptidyl-peptidase I precursor (DPP-I) (DPPI) (Cathepsin C)
(Cathepsin J) (Dipeptidyl transferase) [Contains:
Dipeptidyl-peptidase I exclusion domain chain;
Dipeptidyl-peptidase I heavy chain; Dipeptidyl-peptidase
I light chain]
Length = 462
Score = 137 bits (345), Expect = 8e-33
Identities = 65/107 (60%), Positives = 81/107 (75%), Gaps = 1/107 (0%)
Frame = +3
Query: 3 RMELVKNGPIAVGFEVYDDFMSYSGGVYHHNFGTRKLTTSKFGFNPFELTNHAVLVVGYG 182
++ELVK+GP+AV FEV+DDF+ Y G+YHH T FNPFELTNHAVL+VGYG
Sbjct: 360 KLELVKHGPMAVAFEVHDDFLHYHSGIYHH-------TGLSDPFNPFELTNHAVLLVGYG 412
Query: 183 ETS-SGEKFWIVKNSWGNGWGENGYFRIRRGNDECGIESLGVASEPI 320
+ +G +WIVKNSWG+ WGE+GYFRIRRG DEC IES+ +A+ PI
Sbjct: 413 KDPVTGLDYWIVKNSWGSQWGESGYFRIRRGTDECAIESIAMAAIPI 459
>sp|P25807|CPR1_CAEEL Gut-specific cysteine proteinase precursor
Length = 329
Score = 97.1 bits (240), Expect = 1e-20
Identities = 46/102 (45%), Positives = 62/102 (60%)
Frame = +3
Query: 9 ELVKNGPIAVGFEVYDDFMSYSGGVYHHNFGTRKLTTSKFGFNPFELTNHAVLVVGYGET 188
E+ NGP+ F VY+DF Y GVY H T K+ L HA+ ++G+G T
Sbjct: 239 EIYANGPVEAAFSVYEDFYKYKSGVYKH-------TAGKY------LGGHAIKIIGWG-T 284
Query: 189 SSGEKFWIVKNSWGNGWGENGYFRIRRGNDECGIESLGVASE 314
SG +W+V NSWG WGE+G+F+I RG+D+CGIES VA +
Sbjct: 285 ESGSPYWLVANSWGVNWGESGFFKIYRGDDQCGIESAVVAGK 326
>sp|P43510|CPR6_CAEEL Cathepsin B-like cysteine proteinase 6 precursor (Cysteine
protease-related 6)
Length = 379
Score = 94.4 bits (233), Expect = 7e-20
Identities = 51/109 (46%), Positives = 64/109 (58%)
Frame = +3
Query: 9 ELVKNGPIAVGFEVYDDFMSYSGGVYHHNFGTRKLTTSKFGFNPFELTNHAVLVVGYGET 188
EL+ +GP+ + FEVY+DF++Y GGVY H G K G HAV ++G+G
Sbjct: 269 ELMTHGPLEIAFEVYEDFLNYDGGVYVHTGG-------KLG------GGHAVKLIGWG-I 314
Query: 189 SSGEKFWIVKNSWGNGWGENGYFRIRRGNDECGIESLGVASEPIL*MLT 335
G +W V NSW WGE+G+FRI RG DECGIES V P L LT
Sbjct: 315 DDGIPYWTVANSWNTDWGEDGFFRILRGVDECGIESGVVGGIPKLNSLT 363
>sp|P43508|CPR4_CAEEL Cathepsin B-like cysteine proteinase 4 precursor (Cysteine
protease-related 4)
Length = 335
Score = 93.6 bits (231), Expect = 1e-19
Identities = 45/103 (43%), Positives = 58/103 (56%)
Frame = +3
Query: 9 ELVKNGPIAVGFEVYDDFMSYSGGVYHHNFGTRKLTTSKFGFNPFELTNHAVLVVGYGET 188
E++ +GP+ F VY+DF Y GVY H G EL HA+ ++G+G T
Sbjct: 245 EIIAHGPVEAAFTVYEDFYQYKTGVYVHTTGQ-------------ELGGHAIRILGWG-T 290
Query: 189 SSGEKFWIVKNSWGNGWGENGYFRIRRGNDECGIESLGVASEP 317
+G +W+V NSW WGENGYFRI RG +ECGIE V P
Sbjct: 291 DNGTPYWLVANSWNVNWGENGYFRIIRGTNECGIEHAVVGGVP 333
>sp|P43509|CPR5_CAEEL Cathepsin B-like cysteine proteinase 5 precursor (Cysteine
protease-related 5)
Length = 344
Score = 92.8 bits (229), Expect = 2e-19
Identities = 48/105 (45%), Positives = 59/105 (56%)
Frame = +3
Query: 9 ELVKNGPIAVGFEVYDDFMSYSGGVYHHNFGTRKLTTSKFGFNPFELTNHAVLVVGYGET 188
E++ NGPI V F VY+DF Y+ GVY H G L HAV ++G+G
Sbjct: 250 EILTNGPIEVAFTVYEDFYQYTTGVYVHTAGA-------------SLGGHAVKILGWG-V 295
Query: 189 SSGEKFWIVKNSWGNGWGENGYFRIRRGNDECGIESLGVASEPIL 323
+G +W+V NSW WGE GYFRI RG +ECGIE VA P L
Sbjct: 296 DNGTPYWLVANSWNVAWGEKGYFRIIRGLNECGIEHSAVAGIPDL 340
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 46,571,885
Number of Sequences: 369166
Number of extensions: 972090
Number of successful extensions: 2878
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 2650
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 2703
length of database: 68,354,980
effective HSP length: 96
effective length of database: 50,620,420
effective search space used: 1670473860
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)