Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_001_O06
(397 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P53634|CATC_HUMAN Dipeptidyl-peptidase I precursor (DPP-... 142 2e-34
sp|Q26563|CATC_SCHMA Cathepsin C precursor 139 3e-33
sp|Q60HG6|CATC_MACFA Dipeptidyl-peptidase I precursor (DPP-... 139 3e-33
sp|O97578|CATC_CANFA Dipeptidyl-peptidase I precursor (DPP-... 135 2e-32
sp|P97821|CATC_MOUSE Dipeptidyl-peptidase I precursor (DPP-... 134 5e-32
sp|P80067|CATC_RAT Dipeptidyl-peptidase I precursor (DPP-I)... 132 2e-31
sp|P25807|CPR1_CAEEL Gut-specific cysteine proteinase precu... 95 4e-20
sp|P92131|CATB1_GIALA Cathepsin B-like CP1 precursor (Cathe... 93 2e-19
sp|P43508|CPR4_CAEEL Cathepsin B-like cysteine proteinase 4... 91 8e-19
sp|P43510|CPR6_CAEEL Cathepsin B-like cysteine proteinase 6... 91 8e-19
>sp|P53634|CATC_HUMAN Dipeptidyl-peptidase I precursor (DPP-I) (DPPI) (Cathepsin C)
(Cathepsin J) (Dipeptidyl transferase) [Contains:
Dipeptidyl-peptidase I exclusion domain chain;
Dipeptidyl-peptidase I heavy chain; Dipeptidyl-peptidase
I light chain]
Length = 463
Score = 142 bits (358), Expect = 2e-34
Identities = 67/103 (65%), Positives = 79/103 (76%), Gaps = 1/103 (0%)
Frame = +3
Query: 24 VKNGPIAVGFEVYDDFMSYSGGVYHHNFGTRKLTTSKFGFNPFELTNHAVLVVGYG-ETS 200
V +GP+AV FEVYDDF+ Y G+YHH T + FNPFELTNHAVL+VGYG +++
Sbjct: 365 VHHGPMAVAFEVYDDFLHYKKGIYHH-------TGLRDPFNPFELTNHAVLLVGYGTDSA 417
Query: 201 SGEKFWIVKNSWGNGWGENGYFRIRRGNDECGIESLGVASEPI 329
SG +WIVKNSWG GWGENGYFRIRRG DEC IES+ VA+ PI
Sbjct: 418 SGMDYWIVKNSWGTGWGENGYFRIRRGTDECAIESIAVAATPI 460
>sp|Q26563|CATC_SCHMA Cathepsin C precursor
Length = 454
Score = 139 bits (349), Expect = 3e-33
Identities = 64/104 (61%), Positives = 75/104 (72%), Gaps = 1/104 (0%)
Frame = +3
Query: 24 VKNGPIAVGFEVYDDFMSYSGGVYHHNFGTRKLTTSKFGFNPFELTNHAVLVVGYG-ETS 200
+ NGP VGFEVY+DF Y G+YHH + T + FNPFELTNHAVL+VGYG +
Sbjct: 355 ISNGPFPVGFEVYEDFQFYKEGIYHHT----TVQTDHYNFNPFELTNHAVLLVGYGVDKL 410
Query: 201 SGEKFWIVKNSWGNGWGENGYFRIRRGNDECGIESLGVASEPIL 332
SGE +W VKNSWG WGE GYFRI RG DECG+ESLGV +P+L
Sbjct: 411 SGEPYWKVKNSWGVEWGEQGYFRILRGTDECGVESLGVRFDPVL 454
>sp|Q60HG6|CATC_MACFA Dipeptidyl-peptidase I precursor (DPP-I) (DPPI) (Cathepsin C)
(Cathepsin J) (Dipeptidyl transferase) [Contains:
Dipeptidyl-peptidase I exclusion domain chain;
Dipeptidyl-peptidase I heavy chain; Dipeptidyl-peptidase
I light chain]
Length = 463
Score = 139 bits (349), Expect = 3e-33
Identities = 65/103 (63%), Positives = 78/103 (75%), Gaps = 1/103 (0%)
Frame = +3
Query: 24 VKNGPIAVGFEVYDDFMSYSGGVYHHNFGTRKLTTSKFGFNPFELTNHAVLVVGYG-ETS 200
V +GP+AV FEVYDDF+ Y G+YHH T + FNPFELTNHAVL+VGYG +++
Sbjct: 365 VYHGPLAVAFEVYDDFLHYQNGIYHH-------TGLRDPFNPFELTNHAVLLVGYGTDSA 417
Query: 201 SGEKFWIVKNSWGNGWGENGYFRIRRGNDECGIESLGVASEPI 329
SG +WIVKNSWG WGE+GYFRIRRG DEC IES+ VA+ PI
Sbjct: 418 SGMDYWIVKNSWGTSWGEDGYFRIRRGTDECAIESIAVAATPI 460
>sp|O97578|CATC_CANFA Dipeptidyl-peptidase I precursor (DPP-I) (DPPI) (Cathepsin C)
(Cathepsin J) (Dipeptidyl transferase) [Contains:
Dipeptidyl-peptidase I exclusion domain chain;
Dipeptidyl-peptidase I heavy chain 1;
Dipeptidyl-peptidase I heavy chain 2;
Dipeptidyl-peptidase I heavy chain 3;
Dipeptidyl-peptidase I heavy chain 4;
Dipeptidyl-peptidase I light chain]
Length = 435
Score = 135 bits (341), Expect = 2e-32
Identities = 64/103 (62%), Positives = 79/103 (76%), Gaps = 1/103 (0%)
Frame = +3
Query: 24 VKNGPIAVGFEVYDDFMSYSGGVYHHNFGTRKLTTSKFGFNPFELTNHAVLVVGYG-ETS 200
V++GP+AV FEVYDDF Y G+Y+H T + FNPFELTNHAVL+VGYG +++
Sbjct: 337 VRHGPMAVAFEVYDDFFHYQKGIYYH-------TGLRDPFNPFELTNHAVLLVGYGTDSA 389
Query: 201 SGEKFWIVKNSWGNGWGENGYFRIRRGNDECGIESLGVASEPI 329
SG +WIVKNSWG+ WGE+GYFRIRRG DEC IES+ VA+ PI
Sbjct: 390 SGMDYWIVKNSWGSRWGEDGYFRIRRGTDECAIESIAVAATPI 432
>sp|P97821|CATC_MOUSE Dipeptidyl-peptidase I precursor (DPP-I) (DPPI) (Cathepsin C)
(Cathepsin J) (Dipeptidyl transferase) [Contains:
Dipeptidyl-peptidase I exclusion domain chain;
Dipeptidyl-peptidase I heavy chain; Dipeptidyl-peptidase
I light chain]
Length = 462
Score = 134 bits (338), Expect = 5e-32
Identities = 63/103 (61%), Positives = 78/103 (75%), Gaps = 1/103 (0%)
Frame = +3
Query: 24 VKNGPIAVGFEVYDDFMSYSGGVYHHNFGTRKLTTSKFGFNPFELTNHAVLVVGYG-ETS 200
VK+GP+AV FEV+DDF+ Y G+YHH T FNPFELTNHAVL+VGYG +
Sbjct: 364 VKHGPMAVAFEVHDDFLHYHSGIYHH-------TGLSDPFNPFELTNHAVLLVGYGRDPV 416
Query: 201 SGEKFWIVKNSWGNGWGENGYFRIRRGNDECGIESLGVASEPI 329
+G ++WI+KNSWG+ WGE+GYFRIRRG DEC IES+ VA+ PI
Sbjct: 417 TGIEYWIIKNSWGSNWGESGYFRIRRGTDECAIESIAVAAIPI 459
>sp|P80067|CATC_RAT Dipeptidyl-peptidase I precursor (DPP-I) (DPPI) (Cathepsin C)
(Cathepsin J) (Dipeptidyl transferase) [Contains:
Dipeptidyl-peptidase I exclusion domain chain;
Dipeptidyl-peptidase I heavy chain; Dipeptidyl-peptidase
I light chain]
Length = 462
Score = 132 bits (332), Expect = 2e-31
Identities = 63/103 (61%), Positives = 77/103 (74%), Gaps = 1/103 (0%)
Frame = +3
Query: 24 VKNGPIAVGFEVYDDFMSYSGGVYHHNFGTRKLTTSKFGFNPFELTNHAVLVVGYGETS- 200
VK+GP+AV FEV+DDF+ Y G+YHH T FNPFELTNHAVL+VGYG+
Sbjct: 364 VKHGPMAVAFEVHDDFLHYHSGIYHH-------TGLSDPFNPFELTNHAVLLVGYGKDPV 416
Query: 201 SGEKFWIVKNSWGNGWGENGYFRIRRGNDECGIESLGVASEPI 329
+G +WIVKNSWG+ WGE+GYFRIRRG DEC IES+ +A+ PI
Sbjct: 417 TGLDYWIVKNSWGSQWGESGYFRIRRGTDECAIESIAMAAIPI 459
>sp|P25807|CPR1_CAEEL Gut-specific cysteine proteinase precursor
Length = 329
Score = 95.1 bits (235), Expect = 4e-20
Identities = 45/98 (45%), Positives = 60/98 (61%)
Frame = +3
Query: 30 NGPIAVGFEVYDDFMSYSGGVYHHNFGTRKLTTSKFGFNPFELTNHAVLVVGYGETSSGE 209
NGP+ F VY+DF Y GVY H T K+ L HA+ ++G+G T SG
Sbjct: 243 NGPVEAAFSVYEDFYKYKSGVYKH-------TAGKY------LGGHAIKIIGWG-TESGS 288
Query: 210 KFWIVKNSWGNGWGENGYFRIRRGNDECGIESLGVASE 323
+W+V NSWG WGE+G+F+I RG+D+CGIES VA +
Sbjct: 289 PYWLVANSWGVNWGESGFFKIYRGDDQCGIESAVVAGK 326
>sp|P92131|CATB1_GIALA Cathepsin B-like CP1 precursor (Cathepsin B-like protease B1)
Length = 303
Score = 92.8 bits (229), Expect = 2e-19
Identities = 48/99 (48%), Positives = 55/99 (55%)
Frame = +3
Query: 6 AEFGTRVKNGPIAVGFEVYDDFMSYSGGVYHHNFGTRKLTTSKFGFNPFELTNHAVLVVG 185
A G V GP+ VY D Y GVY H +GT L GF HA+ +VG
Sbjct: 208 AIMGMLVAGGPLQTMIVVYADLSYYESGVYKHTYGTINL-----GF-------HALEIVG 255
Query: 186 YGETSSGEKFWIVKNSWGNGWGENGYFRIRRGNDECGIE 302
YG T G +WI+KNSWG WGENGYFRI RG +EC IE
Sbjct: 256 YGTTDDGTDYWIIKNSWGPDWGENGYFRIVRGVNECRIE 294
>sp|P43508|CPR4_CAEEL Cathepsin B-like cysteine proteinase 4 precursor (Cysteine
protease-related 4)
Length = 335
Score = 90.9 bits (224), Expect = 8e-19
Identities = 44/101 (43%), Positives = 56/101 (55%)
Frame = +3
Query: 24 VKNGPIAVGFEVYDDFMSYSGGVYHHNFGTRKLTTSKFGFNPFELTNHAVLVVGYGETSS 203
+ +GP+ F VY+DF Y GVY H G EL HA+ ++G+G T +
Sbjct: 247 IAHGPVEAAFTVYEDFYQYKTGVYVHTTGQ-------------ELGGHAIRILGWG-TDN 292
Query: 204 GEKFWIVKNSWGNGWGENGYFRIRRGNDECGIESLGVASEP 326
G +W+V NSW WGENGYFRI RG +ECGIE V P
Sbjct: 293 GTPYWLVANSWNVNWGENGYFRIIRGTNECGIEHAVVGGVP 333
>sp|P43510|CPR6_CAEEL Cathepsin B-like cysteine proteinase 6 precursor (Cysteine
protease-related 6)
Length = 379
Score = 90.9 bits (224), Expect = 8e-19
Identities = 49/105 (46%), Positives = 61/105 (58%)
Frame = +3
Query: 30 NGPIAVGFEVYDDFMSYSGGVYHHNFGTRKLTTSKFGFNPFELTNHAVLVVGYGETSSGE 209
+GP+ + FEVY+DF++Y GGVY H G K G HAV ++G+G G
Sbjct: 273 HGPLEIAFEVYEDFLNYDGGVYVHTGG-------KLG------GGHAVKLIGWG-IDDGI 318
Query: 210 KFWIVKNSWGNGWGENGYFRIRRGNDECGIESLGVASEPIL*MLT 344
+W V NSW WGE+G+FRI RG DECGIES V P L LT
Sbjct: 319 PYWTVANSWNTDWGEDGFFRILRGVDECGIESGVVGGIPKLNSLT 363
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 48,623,068
Number of Sequences: 369166
Number of extensions: 1020063
Number of successful extensions: 2929
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 2709
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 2760
length of database: 68,354,980
effective HSP length: 97
effective length of database: 50,435,685
effective search space used: 1714813290
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)