Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_014_K04
(795 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P53634|CATC_HUMAN Dipeptidyl-peptidase I precursor (DPP-... 214 2e-55
sp|P97821|CATC_MOUSE Dipeptidyl-peptidase I precursor (DPP-... 213 4e-55
sp|Q60HG6|CATC_MACFA Dipeptidyl-peptidase I precursor (DPP-... 210 3e-54
sp|P80067|CATC_RAT Dipeptidyl-peptidase I precursor (DPP-I)... 207 3e-53
sp|O97578|CATC_CANFA Dipeptidyl-peptidase I precursor (DPP-... 202 7e-52
sp|Q26563|CATC_SCHMA Cathepsin C precursor 173 4e-43
sp|Q90686|CATK_CHICK Cathepsin K precursor (JTAP-1) 53 8e-07
sp|P43296|RD19A_ARATH Cysteine proteinase RD19a precursor (... 53 1e-06
sp|P80884|ANAN_ANACO Ananain precursor 52 2e-06
sp|P09668|CATH_HUMAN Cathepsin H precursor [Contains: Cathe... 51 3e-06
>sp|P53634|CATC_HUMAN Dipeptidyl-peptidase I precursor (DPP-I) (DPPI) (Cathepsin C)
(Cathepsin J) (Dipeptidyl transferase) [Contains:
Dipeptidyl-peptidase I exclusion domain chain;
Dipeptidyl-peptidase I heavy chain; Dipeptidyl-peptidase
I light chain]
Length = 463
Score = 214 bits (545), Expect = 2e-55
Identities = 121/284 (42%), Positives = 159/284 (55%), Gaps = 19/284 (6%)
Frame = +1
Query: 1 ILLAFCLVQLSVS-----DTPANCTYQDVIGKWQVFTGNF----NVSCSTSKLVATKTLT 153
+LLA L+ LS DTPANCTY D++G W G+ +V+CS K +
Sbjct: 7 LLLAALLLLLSGDGAVRCDTPANCTYLDLLGTWVFQVGSSGSQRDVNCSVMGPQEKKVVV 66
Query: 154 LIYP-NWAVDEFGNYGKWTLIYNQGFEVTITNKKYFGFFDYKKINSTYTISYCDRLQPSW 330
+ + A D+ GN G +T+IYNQGFE+ + + K+F FF YK+ S T +YC+ W
Sbjct: 67 YLQKLDTAYDDLGNSGHFTIIYNQGFEIVLNDYKWFAFFKYKEEGSKVT-TYCNETMTGW 125
Query: 331 FHDVLIRQWQCFKAQRTTTLKE---------KNNVLPHSNIFALTSLRYGSQKRIVDKIN 483
HDVL R W CF ++ T E KN+ +SN Y V IN
Sbjct: 126 VHDVLGRNWACFTGKKVGTASENVYVNTAHLKNSQEKYSNRL------YKYDHNFVKAIN 179
Query: 484 LENNGWTAKDYPEFHEKTLYEVINMAGGSRSKLERPKPAPITKSILDSVKLIPKSFDWRN 663
WTA Y E+ TL ++I +GG K+ RPKPAP+T I + +P S+DWRN
Sbjct: 180 AIQKSWTATTYMEYETLTLGDMIRRSGGHSRKIPRPKPAPLTAEIQQKILHLPTSWDWRN 239
Query: 664 VNGLNYVSPVRNQGGCGSCYSFASAGMLEARYRIRSNNTVRPIL 795
V+G+N+VSPVRNQ CGSCYSFAS GMLEAR RI +NN+ PIL
Sbjct: 240 VHGINFVSPVRNQASCGSCYSFASMGMLEARIRILTNNSQTPIL 283
>sp|P97821|CATC_MOUSE Dipeptidyl-peptidase I precursor (DPP-I) (DPPI) (Cathepsin C)
(Cathepsin J) (Dipeptidyl transferase) [Contains:
Dipeptidyl-peptidase I exclusion domain chain;
Dipeptidyl-peptidase I heavy chain; Dipeptidyl-peptidase
I light chain]
Length = 462
Score = 213 bits (543), Expect = 4e-55
Identities = 120/277 (43%), Positives = 159/277 (57%), Gaps = 12/277 (4%)
Frame = +1
Query: 1 ILLAFCLVQLSVSDTPANCTYQDVIGKWQVFTG----NFNVSCSTSKLVATKTLTLIYP- 165
+LL C V+ SDTPANCTY D++G W G +++CS + K + +
Sbjct: 15 VLLGVCTVR---SDTPANCTYPDLLGTWVFQVGPRSSRSDINCSVMEATEEKVVVHLKKL 71
Query: 166 NWAVDEFGNYGKWTLIYNQGFEVTITNKKYFGFFDYKKINSTYTISYCDRLQPSWFHDVL 345
+ A DE GN G +TLIYNQGFE+ + + K+F FF Y+ T ISYC W HDVL
Sbjct: 72 DTAYDELGNSGHFTLIYNQGFEIVLNDYKWFAFFKYEVRGHT-AISYCHETMTGWVHDVL 130
Query: 346 IRQWQCFKAQRTTTLKEKNNVLPHSNIFALTSLR-------YGSQKRIVDKINLENNGWT 504
R W CF ++ + EK N+ N L L+ Y V IN WT
Sbjct: 131 GRNWACFVGKKVESHIEKVNM----NAAHLGGLQERYSERLYTHNHNFVKAINTVQKSWT 186
Query: 505 AKDYPEFHEKTLYEVINMAGGSRSKLERPKPAPITKSILDSVKLIPKSFDWRNVNGLNYV 684
A Y E+ + +L ++I +G S+ ++ RPKPAP+T I + +P+S+DWRNV G+NYV
Sbjct: 187 ATAYKEYEKMSLRDLIRRSGHSQ-RIPRPKPAPMTDEIQQQILNLPESWDWRNVQGVNYV 245
Query: 685 SPVRNQGGCGSCYSFASAGMLEARYRIRSNNTVRPIL 795
SPVRNQ CGSCYSFAS GMLEAR RI +NN+ PIL
Sbjct: 246 SPVRNQESCGSCYSFASMGMLEARIRILTNNSQTPIL 282
>sp|Q60HG6|CATC_MACFA Dipeptidyl-peptidase I precursor (DPP-I) (DPPI) (Cathepsin C)
(Cathepsin J) (Dipeptidyl transferase) [Contains:
Dipeptidyl-peptidase I exclusion domain chain;
Dipeptidyl-peptidase I heavy chain; Dipeptidyl-peptidase
I light chain]
Length = 463
Score = 210 bits (535), Expect = 3e-54
Identities = 120/283 (42%), Positives = 156/283 (55%), Gaps = 19/283 (6%)
Frame = +1
Query: 4 LLAFCLVQLSVS-----DTPANCTYQDVIGKWQVFTGNF----NVSCSTSKLVATKTLTL 156
LLA L+ LS DTPANCTY D++G W G+ +V+CS K +
Sbjct: 8 LLAALLLLLSGDRAVRCDTPANCTYLDLLGTWVFQVGSSGSLRDVNCSVMGPPEKKVVVH 67
Query: 157 IYP-NWAVDEFGNYGKWTLIYNQGFEVTITNKKYFGFFDYKKINSTYTISYCDRLQPSWF 333
+ + A D+ GN G +T+IYNQGFE+ + + K+F FF YK+ TI YC+ W
Sbjct: 68 LQKLDTAYDDLGNSGHFTIIYNQGFEIVLNDYKWFAFFKYKEEGIKVTI-YCNETMTGWV 126
Query: 334 HDVLIRQWQCFKAQRTTTLKE---------KNNVLPHSNIFALTSLRYGSQKRIVDKINL 486
HDVL R W CF ++ T E KN+ +SN Y V IN
Sbjct: 127 HDVLGRNWACFTGKKVGTASENVYVNTAHLKNSQEKYSNRL------YKYDHNFVKAINA 180
Query: 487 ENNGWTAKDYPEFHEKTLYEVINMAGGSRSKLERPKPAPITKSILDSVKLIPKSFDWRNV 666
WTA Y E+ TL ++I +GG K+ RPKP P+T I + +P S+DWRNV
Sbjct: 181 IQKSWTATTYMEYETLTLGDMIKRSGGHSRKIPRPKPTPLTAEIQQKILHLPTSWDWRNV 240
Query: 667 NGLNYVSPVRNQGGCGSCYSFASAGMLEARYRIRSNNTVRPIL 795
+G+N+VSPVRNQ CGSCYSFAS GMLEAR RI +NN+ PIL
Sbjct: 241 HGINFVSPVRNQASCGSCYSFASVGMLEARIRILTNNSQTPIL 283
>sp|P80067|CATC_RAT Dipeptidyl-peptidase I precursor (DPP-I) (DPPI) (Cathepsin C)
(Cathepsin J) (Dipeptidyl transferase) [Contains:
Dipeptidyl-peptidase I exclusion domain chain;
Dipeptidyl-peptidase I heavy chain; Dipeptidyl-peptidase
I light chain]
Length = 462
Score = 207 bits (527), Expect = 3e-53
Identities = 117/277 (42%), Positives = 155/277 (55%), Gaps = 12/277 (4%)
Frame = +1
Query: 1 ILLAFCLVQLSVSDTPANCTYQDVIGKWQVFTG----NFNVSCSTSKLVATK-TLTLIYP 165
+LL C V SDTPANCTY D++G W G +++CS + K + L
Sbjct: 15 VLLGVCTVS---SDTPANCTYPDLLGTWVFQVGPRHPRSHINCSVMEPTEEKVVIHLKKL 71
Query: 166 NWAVDEFGNYGKWTLIYNQGFEVTITNKKYFGFFDYKKINSTYTISYCDRLQPSWFHDVL 345
+ A DE GN G +TLIYNQGFE+ + + K+F FF Y ++ + ISYC W HD L
Sbjct: 72 DTAYDEVGNSGYFTLIYNQGFEIVLNDYKWFAFFKY-EVKGSRAISYCHETMTGWVHDYL 130
Query: 346 IRQWQCFKAQRTTTLKEKNNVLPHSNIFALTSLR-------YGSQKRIVDKINLENNGWT 504
R W CF ++ EK V N+ L L+ Y V IN WT
Sbjct: 131 GRNWACFVGKKMANHSEKVYV----NVAHLGGLQEKYSERLYSHHHNFVKAINSVQKSWT 186
Query: 505 AKDYPEFHEKTLYEVINMAGGSRSKLERPKPAPITKSILDSVKLIPKSFDWRNVNGLNYV 684
A Y + + ++ ++I +G S ++ RPKPAPIT I + +P+S+DWRNV G+N+V
Sbjct: 187 ATTYRRYEKLSIRDLIRRSGHS-GRILRPKPAPITDEIQQQILSLPESWDWRNVRGINFV 245
Query: 685 SPVRNQGGCGSCYSFASAGMLEARYRIRSNNTVRPIL 795
SPVRNQ CGSCYSFAS GMLEAR RI +NN+ PIL
Sbjct: 246 SPVRNQESCGSCYSFASIGMLEARIRILTNNSQTPIL 282
>sp|O97578|CATC_CANFA Dipeptidyl-peptidase I precursor (DPP-I) (DPPI) (Cathepsin C)
(Cathepsin J) (Dipeptidyl transferase) [Contains:
Dipeptidyl-peptidase I exclusion domain chain;
Dipeptidyl-peptidase I heavy chain 1;
Dipeptidyl-peptidase I heavy chain 2;
Dipeptidyl-peptidase I heavy chain 3;
Dipeptidyl-peptidase I heavy chain 4;
Dipeptidyl-peptidase I light chain]
Length = 435
Score = 202 bits (515), Expect = 7e-52
Identities = 114/264 (43%), Positives = 147/264 (55%), Gaps = 12/264 (4%)
Frame = +1
Query: 40 DTPANCTYQDVIGKWQVF----TGNFNVSCSTSKLVATKTLTLIYP-NWAVDEFGNYGKW 204
DTPANCT+ +++G W VF G+ +V+CS K + + + A D FGN G +
Sbjct: 1 DTPANCTHPELLGTW-VFQVGPAGSRSVNCSVMGPPEKKVVVHLEKLDTAYDNFGNTGHF 59
Query: 205 TLIYNQGFEVTITNKKYFGFFDYKKINSTYTISYCDRLQPSWFHDVLIRQWQCFKAQRTT 384
T+IYNQGFE+ + + K+F FF YK+ T SYC+ W HDVL R W CF +
Sbjct: 60 TIIYNQGFEIVLNDYKWFAFFKYKEEGHKVT-SYCNETMTGWVHDVLGRNWACFTGTKMG 118
Query: 385 TLKEKNNV-------LPHSNIFALTSLRYGSQKRIVDKINLENNGWTAKDYPEFHEKTLY 543
T EK V L +N L Y V IN WTA Y E+ TL
Sbjct: 119 TTSEKAKVNTKHIERLQENNSNRLYKYNY----EFVKAINTIQKSWTATRYIEYETLTLR 174
Query: 544 EVINMAGGSRSKLERPKPAPITKSILDSVKLIPKSFDWRNVNGLNYVSPVRNQGGCGSCY 723
+++ GG K+ RPKP P+T I + + +P S+DWRNV G N+VSPVRNQ CGSCY
Sbjct: 175 DMMTRVGGR--KIPRPKPTPLTAEIHEEISRLPTSWDWRNVRGTNFVSPVRNQASCGSCY 232
Query: 724 SFASAGMLEARYRIRSNNTVRPIL 795
+FAS MLEAR RI +NNT PIL
Sbjct: 233 AFASTAMLEARIRILTNNTQTPIL 256
>sp|Q26563|CATC_SCHMA Cathepsin C precursor
Length = 454
Score = 173 bits (439), Expect = 4e-43
Identities = 105/273 (38%), Positives = 148/273 (54%), Gaps = 8/273 (2%)
Frame = +1
Query: 1 ILLAFCLVQLSVSDTPANCTYQDVIGKWQVFTGNFNVSCSTSKLVATKT--LTLIYPNWA 174
IL+ ++ + +DTPANCTY+D G+W+ G++ C KL + ++ ++L+YP+ A
Sbjct: 8 ILIILACLRFTCADTPANCTYEDAHGRWKFHIGDYQSKCP-EKLNSKQSVVISLLYPDIA 66
Query: 175 VDEFGNYGKWTLIYNQGFEVTITNKKYFGFFDYKKINSTYTISYCDRLQPSWFHDVLIRQ 354
+DEFGN G WTLIYNQGFEVTI ++K+ F YK N + C + P W HD LI
Sbjct: 67 IDEFGNRGHWTLIYNQGFEVTINHRKWLVIFAYKS-NGEFN---CHKSMPMWTHDTLIDS 122
Query: 355 WQCFKAQRTTTLKEKNNVLPHSNIFALTSLRYGSQKRIVDKINLENNGWTAKDYPEFHEK 534
+ K N L S F T Y V KIN W + YPE +
Sbjct: 123 GSVCSGKIGVHDKFHINKLFGSKSFGRT--LYHINPSFVGKINAHQKSWRGEIYPELSKY 180
Query: 535 TLYEVINMAGGSRSKLERP----KPAPITKSILDSVKLIPKSFDWRNV--NGLNYVSPVR 696
T+ E+ N AGG +S + RP + P +K ++ +P FDW + + V+P+R
Sbjct: 181 TIDELRNRAGGVKSMVTRPSVLNRKTP-SKELISLTGNLPLEFDWTSPPDGSRSPVTPIR 239
Query: 697 NQGGCGSCYSFASAGMLEARYRIRSNNTVRPIL 795
NQG CGSCY+ SA LEAR R+ SN + +PIL
Sbjct: 240 NQGICGSCYASPSAAALEARIRLVSNFSEQPIL 272
>sp|Q90686|CATK_CHICK Cathepsin K precursor (JTAP-1)
Length = 334
Score = 53.1 bits (126), Expect = 8e-07
Identities = 30/81 (37%), Positives = 44/81 (54%)
Frame = +1
Query: 529 EKTLYEVINMAGGSRSKLERPKPAPITKSILDSVKLIPKSFDWRNVNGLNYVSPVRNQGG 708
+ T EV+ G R RP+P T + D P + DWR YV+PV++QG
Sbjct: 85 DMTSEEVVRTMTGLRVPRSRPRPNG-TLYVPDWSSRAPAAVDWRRKG---YVTPVKDQGQ 140
Query: 709 CGSCYSFASAGMLEARYRIRS 771
CGSC++F+S G LE + + R+
Sbjct: 141 CGSCWAFSSVGALEGQLKRRT 161
>sp|P43296|RD19A_ARATH Cysteine proteinase RD19a precursor (RD19)
Length = 368
Score = 52.8 bits (125), Expect = 1e-06
Identities = 30/77 (38%), Positives = 44/77 (57%)
Frame = +1
Query: 520 EFHEKTLYEVINMAGGSRSKLERPKPAPITKSILDSVKLIPKSFDWRNVNGLNYVSPVRN 699
+F + T E G RS + PK A K+ + + +P+ FDWR+ V+PV+N
Sbjct: 98 QFSDLTRSEFRKKHLGVRSGFKLPKDA--NKAPILPTENLPEDFDWRDHGA---VTPVKN 152
Query: 700 QGGCGSCYSFASAGMLE 750
QG CGSC+SF++ G LE
Sbjct: 153 QGSCGSCWSFSATGALE 169
>sp|P80884|ANAN_ANACO Ananain precursor
Length = 345
Score = 52.0 bits (123), Expect = 2e-06
Identities = 40/159 (25%), Positives = 73/159 (45%)
Frame = +1
Query: 307 CDRLQPSWFHDVLIRQWQCFKAQRTTTLKEKNNVLPHSNIFALTSLRYGSQKRIVDKINL 486
CD +PS D +++Q++ + A+ K+ + + IF + ++ N
Sbjct: 26 CD--EPS---DPMMKQFEEWMAEYGRVYKDNDEKMLRFQIFK-------NNVNHIETFNN 73
Query: 487 ENNGWTAKDYPEFHEKTLYEVINMAGGSRSKLERPKPAPITKSILDSVKLIPKSFDWRNV 666
N +F + T E + G L + ++ +D + +P+S DWR+
Sbjct: 74 RNGNSYTLGINQFTDMTNNEFVAQYTGLSLPLNIKREPVVSFDDVD-ISSVPQSIDWRDS 132
Query: 667 NGLNYVSPVRNQGGCGSCYSFASAGMLEARYRIRSNNTV 783
V+ V+NQG CGSC++FAS +E+ Y+I+ N V
Sbjct: 133 GA---VTSVKNQGRCGSCWAFASIATVESIYKIKRGNLV 168
>sp|P09668|CATH_HUMAN Cathepsin H precursor [Contains: Cathepsin H mini chain; Cathepsin
H heavy chain; Cathepsin H light chain]
Length = 335
Score = 51.2 bits (121), Expect = 3e-06
Identities = 37/100 (37%), Positives = 51/100 (51%), Gaps = 3/100 (3%)
Frame = +1
Query: 475 KINLENNG-WTAK-DYPEFHEKTLYEVINMAGGSRSKLERPKPAPITKS-ILDSVKLIPK 645
KIN NNG T K +F + + E+ + + P+ TKS L P
Sbjct: 64 KINAHNNGNHTFKMALNQFSDMSFAEIKH-----KYLWSEPQNCSATKSNYLRGTGPYPP 118
Query: 646 SFDWRNVNGLNYVSPVRNQGGCGSCYSFASAGMLEARYRI 765
S DWR N+VSPV+NQG CGSC++F++ G LE+ I
Sbjct: 119 SVDWRKKG--NFVSPVKNQGACGSCWTFSTTGALESAIAI 156
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 93,345,329
Number of Sequences: 369166
Number of extensions: 1915725
Number of successful extensions: 4782
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4511
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4694
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 7473924075
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)