Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_009_K11
(380 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P53634|CATC_HUMAN Dipeptidyl-peptidase I precursor (DPP-... 144 6e-35
sp|Q60HG6|CATC_MACFA Dipeptidyl-peptidase I precursor (DPP-... 140 9e-34
sp|Q26563|CATC_SCHMA Cathepsin C precursor 140 1e-33
sp|O97578|CATC_CANFA Dipeptidyl-peptidase I precursor (DPP-... 138 3e-33
sp|P97821|CATC_MOUSE Dipeptidyl-peptidase I precursor (DPP-... 135 4e-32
sp|P80067|CATC_RAT Dipeptidyl-peptidase I precursor (DPP-I)... 132 2e-31
sp|P25807|CPR1_CAEEL Gut-specific cysteine proteinase precu... 95 4e-20
sp|P92131|CATB1_GIALA Cathepsin B-like CP1 precursor (Cathe... 93 2e-19
sp|P43510|CPR6_CAEEL Cathepsin B-like cysteine proteinase 6... 92 3e-19
sp|P92133|CATB3_GIALA Cathepsin B-like CP3 precursor (Cathe... 92 4e-19
>sp|P53634|CATC_HUMAN Dipeptidyl-peptidase I precursor (DPP-I) (DPPI) (Cathepsin C)
(Cathepsin J) (Dipeptidyl transferase) [Contains:
Dipeptidyl-peptidase I exclusion domain chain;
Dipeptidyl-peptidase I heavy chain; Dipeptidyl-peptidase
I light chain]
Length = 463
Score = 144 bits (363), Expect = 6e-35
Identities = 68/104 (65%), Positives = 80/104 (76%), Gaps = 1/104 (0%)
Frame = +3
Query: 3 LVRNGPIAVGFEVYDDFMSYSGGVYHHNFGTRKLTTSKFGFNPFELTNHAVLVVGYG-ET 179
LV +GP+AV FEVYDDF+ Y G+YHH T + FNPFELTNHAVL+VGYG ++
Sbjct: 364 LVHHGPMAVAFEVYDDFLHYKKGIYHH-------TGLRDPFNPFELTNHAVLLVGYGTDS 416
Query: 180 SSGEKFWIVKNSWGNGWGENGYFRIRRGNDECGIESLGVASEPI 311
+SG +WIVKNSWG GWGENGYFRIRRG DEC IES+ VA+ PI
Sbjct: 417 ASGMDYWIVKNSWGTGWGENGYFRIRRGTDECAIESIAVAATPI 460
>sp|Q60HG6|CATC_MACFA Dipeptidyl-peptidase I precursor (DPP-I) (DPPI) (Cathepsin C)
(Cathepsin J) (Dipeptidyl transferase) [Contains:
Dipeptidyl-peptidase I exclusion domain chain;
Dipeptidyl-peptidase I heavy chain; Dipeptidyl-peptidase
I light chain]
Length = 463
Score = 140 bits (353), Expect = 9e-34
Identities = 66/104 (63%), Positives = 79/104 (75%), Gaps = 1/104 (0%)
Frame = +3
Query: 3 LVRNGPIAVGFEVYDDFMSYSGGVYHHNFGTRKLTTSKFGFNPFELTNHAVLVVGYG-ET 179
LV +GP+AV FEVYDDF+ Y G+YHH T + FNPFELTNHAVL+VGYG ++
Sbjct: 364 LVYHGPLAVAFEVYDDFLHYQNGIYHH-------TGLRDPFNPFELTNHAVLLVGYGTDS 416
Query: 180 SSGEKFWIVKNSWGNGWGENGYFRIRRGNDECGIESLGVASEPI 311
+SG +WIVKNSWG WGE+GYFRIRRG DEC IES+ VA+ PI
Sbjct: 417 ASGMDYWIVKNSWGTSWGEDGYFRIRRGTDECAIESIAVAATPI 460
>sp|Q26563|CATC_SCHMA Cathepsin C precursor
Length = 454
Score = 140 bits (352), Expect = 1e-33
Identities = 65/105 (61%), Positives = 76/105 (72%), Gaps = 1/105 (0%)
Frame = +3
Query: 3 LVRNGPIAVGFEVYDDFMSYSGGVYHHNFGTRKLTTSKFGFNPFELTNHAVLVVGYG-ET 179
L+ NGP VGFEVY+DF Y G+YHH + T + FNPFELTNHAVL+VGYG +
Sbjct: 354 LISNGPFPVGFEVYEDFQFYKEGIYHHT----TVQTDHYNFNPFELTNHAVLLVGYGVDK 409
Query: 180 SSGEKFWIVKNSWGNGWGENGYFRIRRGNDECGIESLGVASEPIL 314
SGE +W VKNSWG WGE GYFRI RG DECG+ESLGV +P+L
Sbjct: 410 LSGEPYWKVKNSWGVEWGEQGYFRILRGTDECGVESLGVRFDPVL 454
>sp|O97578|CATC_CANFA Dipeptidyl-peptidase I precursor (DPP-I) (DPPI) (Cathepsin C)
(Cathepsin J) (Dipeptidyl transferase) [Contains:
Dipeptidyl-peptidase I exclusion domain chain;
Dipeptidyl-peptidase I heavy chain 1;
Dipeptidyl-peptidase I heavy chain 2;
Dipeptidyl-peptidase I heavy chain 3;
Dipeptidyl-peptidase I heavy chain 4;
Dipeptidyl-peptidase I light chain]
Length = 435
Score = 138 bits (348), Expect = 3e-33
Identities = 66/104 (63%), Positives = 80/104 (76%), Gaps = 1/104 (0%)
Frame = +3
Query: 3 LVRNGPIAVGFEVYDDFMSYSGGVYHHNFGTRKLTTSKFGFNPFELTNHAVLVVGYG-ET 179
LVR+GP+AV FEVYDDF Y G+Y+H T + FNPFELTNHAVL+VGYG ++
Sbjct: 336 LVRHGPMAVAFEVYDDFFHYQKGIYYH-------TGLRDPFNPFELTNHAVLLVGYGTDS 388
Query: 180 SSGEKFWIVKNSWGNGWGENGYFRIRRGNDECGIESLGVASEPI 311
+SG +WIVKNSWG+ WGE+GYFRIRRG DEC IES+ VA+ PI
Sbjct: 389 ASGMDYWIVKNSWGSRWGEDGYFRIRRGTDECAIESIAVAATPI 432
>sp|P97821|CATC_MOUSE Dipeptidyl-peptidase I precursor (DPP-I) (DPPI) (Cathepsin C)
(Cathepsin J) (Dipeptidyl transferase) [Contains:
Dipeptidyl-peptidase I exclusion domain chain;
Dipeptidyl-peptidase I heavy chain; Dipeptidyl-peptidase
I light chain]
Length = 462
Score = 135 bits (339), Expect = 4e-32
Identities = 63/104 (60%), Positives = 79/104 (75%), Gaps = 1/104 (0%)
Frame = +3
Query: 3 LVRNGPIAVGFEVYDDFMSYSGGVYHHNFGTRKLTTSKFGFNPFELTNHAVLVVGYG-ET 179
LV++GP+AV FEV+DDF+ Y G+YHH T FNPFELTNHAVL+VGYG +
Sbjct: 363 LVKHGPMAVAFEVHDDFLHYHSGIYHH-------TGLSDPFNPFELTNHAVLLVGYGRDP 415
Query: 180 SSGEKFWIVKNSWGNGWGENGYFRIRRGNDECGIESLGVASEPI 311
+G ++WI+KNSWG+ WGE+GYFRIRRG DEC IES+ VA+ PI
Sbjct: 416 VTGIEYWIIKNSWGSNWGESGYFRIRRGTDECAIESIAVAAIPI 459
>sp|P80067|CATC_RAT Dipeptidyl-peptidase I precursor (DPP-I) (DPPI) (Cathepsin C)
(Cathepsin J) (Dipeptidyl transferase) [Contains:
Dipeptidyl-peptidase I exclusion domain chain;
Dipeptidyl-peptidase I heavy chain; Dipeptidyl-peptidase
I light chain]
Length = 462
Score = 132 bits (333), Expect = 2e-31
Identities = 63/104 (60%), Positives = 78/104 (75%), Gaps = 1/104 (0%)
Frame = +3
Query: 3 LVRNGPIAVGFEVYDDFMSYSGGVYHHNFGTRKLTTSKFGFNPFELTNHAVLVVGYGETS 182
LV++GP+AV FEV+DDF+ Y G+YHH T FNPFELTNHAVL+VGYG+
Sbjct: 363 LVKHGPMAVAFEVHDDFLHYHSGIYHH-------TGLSDPFNPFELTNHAVLLVGYGKDP 415
Query: 183 -SGEKFWIVKNSWGNGWGENGYFRIRRGNDECGIESLGVASEPI 311
+G +WIVKNSWG+ WGE+GYFRIRRG DEC IES+ +A+ PI
Sbjct: 416 VTGLDYWIVKNSWGSQWGESGYFRIRRGTDECAIESIAMAAIPI 459
>sp|P25807|CPR1_CAEEL Gut-specific cysteine proteinase precursor
Length = 329
Score = 95.1 bits (235), Expect = 4e-20
Identities = 45/98 (45%), Positives = 60/98 (61%)
Frame = +3
Query: 12 NGPIAVGFEVYDDFMSYSGGVYHHNFGTRKLTTSKFGFNPFELTNHAVLVVGYGETSSGE 191
NGP+ F VY+DF Y GVY H T K+ L HA+ ++G+G T SG
Sbjct: 243 NGPVEAAFSVYEDFYKYKSGVYKH-------TAGKY------LGGHAIKIIGWG-TESGS 288
Query: 192 KFWIVKNSWGNGWGENGYFRIRRGNDECGIESLGVASE 305
+W+V NSWG WGE+G+F+I RG+D+CGIES VA +
Sbjct: 289 PYWLVANSWGVNWGESGFFKIYRGDDQCGIESAVVAGK 326
>sp|P92131|CATB1_GIALA Cathepsin B-like CP1 precursor (Cathepsin B-like protease B1)
Length = 303
Score = 92.8 bits (229), Expect = 2e-19
Identities = 47/94 (50%), Positives = 54/94 (57%)
Frame = +3
Query: 3 LVRNGPIAVGFEVYDDFMSYSGGVYHHNFGTRKLTTSKFGFNPFELTNHAVLVVGYGETS 182
LV GP+ VY D Y GVY H +GT L GF HA+ +VGYG T
Sbjct: 213 LVAGGPLQTMIVVYADLSYYESGVYKHTYGTINL-----GF-------HALEIVGYGTTD 260
Query: 183 SGEKFWIVKNSWGNGWGENGYFRIRRGNDECGIE 284
G +WI+KNSWG WGENGYFRI RG +EC IE
Sbjct: 261 DGTDYWIIKNSWGPDWGENGYFRIVRGVNECRIE 294
>sp|P43510|CPR6_CAEEL Cathepsin B-like cysteine proteinase 6 precursor (Cysteine
protease-related 6)
Length = 379
Score = 92.4 bits (228), Expect = 3e-19
Identities = 50/108 (46%), Positives = 63/108 (58%)
Frame = +3
Query: 3 LVRNGPIAVGFEVYDDFMSYSGGVYHHNFGTRKLTTSKFGFNPFELTNHAVLVVGYGETS 182
L+ +GP+ + FEVY+DF++Y GGVY H G K G HAV ++G+G
Sbjct: 270 LMTHGPLEIAFEVYEDFLNYDGGVYVHTGG-------KLG------GGHAVKLIGWG-ID 315
Query: 183 SGEKFWIVKNSWGNGWGENGYFRIRRGNDECGIESLGVASEPIL*MLT 326
G +W V NSW WGE+G+FRI RG DECGIES V P L LT
Sbjct: 316 DGIPYWTVANSWNTDWGEDGFFRILRGVDECGIESGVVGGIPKLNSLT 363
>sp|P92133|CATB3_GIALA Cathepsin B-like CP3 precursor (Cathepsin B-like protease B3)
Length = 299
Score = 92.0 bits (227), Expect = 4e-19
Identities = 44/94 (46%), Positives = 52/94 (55%)
Frame = +3
Query: 3 LVRNGPIAVGFEVYDDFMSYSGGVYHHNFGTRKLTTSKFGFNPFELTNHAVLVVGYGETS 182
L GP+ F VY DFM Y GVY H +G + HAV +VGYG
Sbjct: 209 LATGGPLQTAFTVYSDFMYYESGVYQHTYGRVE-------------GGHAVDMVGYGTDD 255
Query: 183 SGEKFWIVKNSWGNGWGENGYFRIRRGNDECGIE 284
G +WI+KNSWG WGE+GYFRI R +ECGIE
Sbjct: 256 DGVDYWIIKNSWGPDWGEDGYFRIIRMTNECGIE 289
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 45,500,322
Number of Sequences: 369166
Number of extensions: 950779
Number of successful extensions: 2804
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 2585
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 2636
length of database: 68,354,980
effective HSP length: 93
effective length of database: 51,174,625
effective search space used: 1688762625
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)