Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_008_M21
(337 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P53634|CATC_HUMAN Dipeptidyl-peptidase I precursor (DPP-... 124 9e-29
sp|Q60HG6|CATC_MACFA Dipeptidyl-peptidase I precursor (DPP-... 120 1e-27
sp|Q26563|CATC_SCHMA Cathepsin C precursor 118 4e-27
sp|O97578|CATC_CANFA Dipeptidyl-peptidase I precursor (DPP-... 116 2e-26
sp|P97821|CATC_MOUSE Dipeptidyl-peptidase I precursor (DPP-... 115 2e-26
sp|P80067|CATC_RAT Dipeptidyl-peptidase I precursor (DPP-I)... 113 1e-25
sp|P92131|CATB1_GIALA Cathepsin B-like CP1 precursor (Cathe... 83 2e-16
sp|P25807|CPR1_CAEEL Gut-specific cysteine proteinase precu... 80 1e-15
sp|P92133|CATB3_GIALA Cathepsin B-like CP3 precursor (Cathe... 79 3e-15
sp|P49935|CATH_MOUSE Cathepsin H precursor (Cathepsin B3) (... 79 3e-15
>sp|P53634|CATC_HUMAN Dipeptidyl-peptidase I precursor (DPP-I) (DPPI) (Cathepsin C)
(Cathepsin J) (Dipeptidyl transferase) [Contains:
Dipeptidyl-peptidase I exclusion domain chain;
Dipeptidyl-peptidase I heavy chain; Dipeptidyl-peptidase
I light chain]
Length = 463
Score = 124 bits (310), Expect = 9e-29
Identities = 58/90 (64%), Positives = 68/90 (75%), Gaps = 1/90 (1%)
Frame = +3
Query: 3 DDFMSYSGGVYHHNFGTRKLTTSKFGFNPFELTNHAVLVVGYG-ETSSGEKFWIVKNSWG 179
DDF+ Y G+YHH T + FNPFELTNHAVL+VGYG +++SG +WIVKNSWG
Sbjct: 378 DDFLHYKKGIYHH-------TGLRDPFNPFELTNHAVLLVGYGTDSASGMDYWIVKNSWG 430
Query: 180 NGWGENGYFRIRRGNDECGIESLGVASEPI 269
GWGENGYFRIRRG DEC IES+ VA+ PI
Sbjct: 431 TGWGENGYFRIRRGTDECAIESIAVAATPI 460
>sp|Q60HG6|CATC_MACFA Dipeptidyl-peptidase I precursor (DPP-I) (DPPI) (Cathepsin C)
(Cathepsin J) (Dipeptidyl transferase) [Contains:
Dipeptidyl-peptidase I exclusion domain chain;
Dipeptidyl-peptidase I heavy chain; Dipeptidyl-peptidase
I light chain]
Length = 463
Score = 120 bits (301), Expect = 1e-27
Identities = 56/90 (62%), Positives = 67/90 (74%), Gaps = 1/90 (1%)
Frame = +3
Query: 3 DDFMSYSGGVYHHNFGTRKLTTSKFGFNPFELTNHAVLVVGYG-ETSSGEKFWIVKNSWG 179
DDF+ Y G+YHH T + FNPFELTNHAVL+VGYG +++SG +WIVKNSWG
Sbjct: 378 DDFLHYQNGIYHH-------TGLRDPFNPFELTNHAVLLVGYGTDSASGMDYWIVKNSWG 430
Query: 180 NGWGENGYFRIRRGNDECGIESLGVASEPI 269
WGE+GYFRIRRG DEC IES+ VA+ PI
Sbjct: 431 TSWGEDGYFRIRRGTDECAIESIAVAATPI 460
>sp|Q26563|CATC_SCHMA Cathepsin C precursor
Length = 454
Score = 118 bits (296), Expect = 4e-27
Identities = 55/91 (60%), Positives = 65/91 (71%), Gaps = 1/91 (1%)
Frame = +3
Query: 3 DDFMSYSGGVYHHNFGTRKLTTSKFGFNPFELTNHAVLVVGYG-ETSSGEKFWIVKNSWG 179
+DF Y G+YHH + T + FNPFELTNHAVL+VGYG + SGE +W VKNSWG
Sbjct: 368 EDFQFYKEGIYHHT----TVQTDHYNFNPFELTNHAVLLVGYGVDKLSGEPYWKVKNSWG 423
Query: 180 NGWGENGYFRIRRGNDECGIESLGVASEPIL 272
WGE GYFRI RG DECG+ESLGV +P+L
Sbjct: 424 VEWGEQGYFRILRGTDECGVESLGVRFDPVL 454
>sp|O97578|CATC_CANFA Dipeptidyl-peptidase I precursor (DPP-I) (DPPI) (Cathepsin C)
(Cathepsin J) (Dipeptidyl transferase) [Contains:
Dipeptidyl-peptidase I exclusion domain chain;
Dipeptidyl-peptidase I heavy chain 1;
Dipeptidyl-peptidase I heavy chain 2;
Dipeptidyl-peptidase I heavy chain 3;
Dipeptidyl-peptidase I heavy chain 4;
Dipeptidyl-peptidase I light chain]
Length = 435
Score = 116 bits (290), Expect = 2e-26
Identities = 55/90 (61%), Positives = 67/90 (74%), Gaps = 1/90 (1%)
Frame = +3
Query: 3 DDFMSYSGGVYHHNFGTRKLTTSKFGFNPFELTNHAVLVVGYG-ETSSGEKFWIVKNSWG 179
DDF Y G+Y+H T + FNPFELTNHAVL+VGYG +++SG +WIVKNSWG
Sbjct: 350 DDFFHYQKGIYYH-------TGLRDPFNPFELTNHAVLLVGYGTDSASGMDYWIVKNSWG 402
Query: 180 NGWGENGYFRIRRGNDECGIESLGVASEPI 269
+ WGE+GYFRIRRG DEC IES+ VA+ PI
Sbjct: 403 SRWGEDGYFRIRRGTDECAIESIAVAATPI 432
>sp|P97821|CATC_MOUSE Dipeptidyl-peptidase I precursor (DPP-I) (DPPI) (Cathepsin C)
(Cathepsin J) (Dipeptidyl transferase) [Contains:
Dipeptidyl-peptidase I exclusion domain chain;
Dipeptidyl-peptidase I heavy chain; Dipeptidyl-peptidase
I light chain]
Length = 462
Score = 115 bits (289), Expect = 2e-26
Identities = 54/90 (60%), Positives = 66/90 (73%), Gaps = 1/90 (1%)
Frame = +3
Query: 3 DDFMSYSGGVYHHNFGTRKLTTSKFGFNPFELTNHAVLVVGYG-ETSSGEKFWIVKNSWG 179
DDF+ Y G+YHH T FNPFELTNHAVL+VGYG + +G ++WI+KNSWG
Sbjct: 377 DDFLHYHSGIYHH-------TGLSDPFNPFELTNHAVLLVGYGRDPVTGIEYWIIKNSWG 429
Query: 180 NGWGENGYFRIRRGNDECGIESLGVASEPI 269
+ WGE+GYFRIRRG DEC IES+ VA+ PI
Sbjct: 430 SNWGESGYFRIRRGTDECAIESIAVAAIPI 459
>sp|P80067|CATC_RAT Dipeptidyl-peptidase I precursor (DPP-I) (DPPI) (Cathepsin C)
(Cathepsin J) (Dipeptidyl transferase) [Contains:
Dipeptidyl-peptidase I exclusion domain chain;
Dipeptidyl-peptidase I heavy chain; Dipeptidyl-peptidase
I light chain]
Length = 462
Score = 113 bits (283), Expect = 1e-25
Identities = 54/90 (60%), Positives = 65/90 (72%), Gaps = 1/90 (1%)
Frame = +3
Query: 3 DDFMSYSGGVYHHNFGTRKLTTSKFGFNPFELTNHAVLVVGYGETS-SGEKFWIVKNSWG 179
DDF+ Y G+YHH T FNPFELTNHAVL+VGYG+ +G +WIVKNSWG
Sbjct: 377 DDFLHYHSGIYHH-------TGLSDPFNPFELTNHAVLLVGYGKDPVTGLDYWIVKNSWG 429
Query: 180 NGWGENGYFRIRRGNDECGIESLGVASEPI 269
+ WGE+GYFRIRRG DEC IES+ +A+ PI
Sbjct: 430 SQWGESGYFRIRRGTDECAIESIAMAAIPI 459
>sp|P92131|CATB1_GIALA Cathepsin B-like CP1 precursor (Cathepsin B-like protease B1)
Length = 303
Score = 83.2 bits (204), Expect = 2e-16
Identities = 41/79 (51%), Positives = 47/79 (59%)
Frame = +3
Query: 6 DFMSYSGGVYHHNFGTRKLTTSKFGFNPFELTNHAVLVVGYGETSSGEKFWIVKNSWGNG 185
D Y GVY H +GT L GF HA+ +VGYG T G +WI+KNSWG
Sbjct: 228 DLSYYESGVYKHTYGTINL-----GF-------HALEIVGYGTTDDGTDYWIIKNSWGPD 275
Query: 186 WGENGYFRIRRGNDECGIE 242
WGENGYFRI RG +EC IE
Sbjct: 276 WGENGYFRIVRGVNECRIE 294
>sp|P25807|CPR1_CAEEL Gut-specific cysteine proteinase precursor
Length = 329
Score = 80.5 bits (197), Expect = 1e-15
Identities = 39/87 (44%), Positives = 53/87 (60%)
Frame = +3
Query: 3 DDFMSYSGGVYHHNFGTRKLTTSKFGFNPFELTNHAVLVVGYGETSSGEKFWIVKNSWGN 182
+DF Y GVY H T K+ L HA+ ++G+G T SG +W+V NSWG
Sbjct: 254 EDFYKYKSGVYKH-------TAGKY------LGGHAIKIIGWG-TESGSPYWLVANSWGV 299
Query: 183 GWGENGYFRIRRGNDECGIESLGVASE 263
WGE+G+F+I RG+D+CGIES VA +
Sbjct: 300 NWGESGFFKIYRGDDQCGIESAVVAGK 326
>sp|P92133|CATB3_GIALA Cathepsin B-like CP3 precursor (Cathepsin B-like protease B3)
Length = 299
Score = 79.3 bits (194), Expect = 3e-15
Identities = 38/79 (48%), Positives = 45/79 (56%)
Frame = +3
Query: 6 DFMSYSGGVYHHNFGTRKLTTSKFGFNPFELTNHAVLVVGYGETSSGEKFWIVKNSWGNG 185
DFM Y GVY H +G + HAV +VGYG G +WI+KNSWG
Sbjct: 224 DFMYYESGVYQHTYGRVE-------------GGHAVDMVGYGTDDDGVDYWIIKNSWGPD 270
Query: 186 WGENGYFRIRRGNDECGIE 242
WGE+GYFRI R +ECGIE
Sbjct: 271 WGEDGYFRIIRMTNECGIE 289
>sp|P49935|CATH_MOUSE Cathepsin H precursor (Cathepsin B3) (Cathepsin BA) [Contains:
Cathepsin H mini chain; Cathepsin H heavy chain;
Cathepsin H light chain]
Length = 333
Score = 79.0 bits (193), Expect = 3e-15
Identities = 43/89 (48%), Positives = 53/89 (59%)
Frame = +3
Query: 3 DDFMSYSGGVYHHNFGTRKLTTSKFGFNPFELTNHAVLVVGYGETSSGEKFWIVKNSWGN 182
+DF+ Y GVY +SK + NHAVL VGYGE +G +WIVKNSWG+
Sbjct: 255 EDFLMYKSGVY----------SSKSCHKTPDKVNHAVLAVGYGE-QNGLLYWIVKNSWGS 303
Query: 183 GWGENGYFRIRRGNDECGIESLGVASEPI 269
WGENGYF I RG + CG+ + AS PI
Sbjct: 304 QWGENGYFLIERGKNMCGLAA--CASYPI 330
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 41,694,840
Number of Sequences: 369166
Number of extensions: 863319
Number of successful extensions: 2570
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 2372
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 2423
length of database: 68,354,980
effective HSP length: 79
effective length of database: 53,760,915
effective search space used: 1720349280
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)