Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_026_E18
(350 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P53634|CATC_HUMAN Dipeptidyl-peptidase I precursor (DPP-... 132 2e-31
sp|Q60HG6|CATC_MACFA Dipeptidyl-peptidase I precursor (DPP-... 129 3e-30
sp|Q26563|CATC_SCHMA Cathepsin C precursor 127 1e-29
sp|O97578|CATC_CANFA Dipeptidyl-peptidase I precursor (DPP-... 124 5e-29
sp|P97821|CATC_MOUSE Dipeptidyl-peptidase I precursor (DPP-... 122 3e-28
sp|P80067|CATC_RAT Dipeptidyl-peptidase I precursor (DPP-I)... 120 1e-27
sp|P25807|CPR1_CAEEL Gut-specific cysteine proteinase precu... 87 1e-17
sp|P92131|CATB1_GIALA Cathepsin B-like CP1 precursor (Cathe... 87 2e-17
sp|P92133|CATB3_GIALA Cathepsin B-like CP3 precursor (Cathe... 86 3e-17
sp|P43508|CPR4_CAEEL Cathepsin B-like cysteine proteinase 4... 84 1e-16
>sp|P53634|CATC_HUMAN Dipeptidyl-peptidase I precursor (DPP-I) (DPPI) (Cathepsin C)
(Cathepsin J) (Dipeptidyl transferase) [Contains:
Dipeptidyl-peptidase I exclusion domain chain;
Dipeptidyl-peptidase I heavy chain; Dipeptidyl-peptidase
I light chain]
Length = 463
Score = 132 bits (332), Expect = 2e-31
Identities = 62/94 (65%), Positives = 72/94 (76%), Gaps = 1/94 (1%)
Frame = +3
Query: 3 FEVYDDFMSYSGGVYHHNFGTRKLTTSKFGFNPFELTNHAVLVVGYG-ETSSGEKFWIVK 179
FEVYDDF+ Y G+YHH T + FNPFELTNHAVL+VGYG +++SG +WIVK
Sbjct: 374 FEVYDDFLHYKKGIYHH-------TGLRDPFNPFELTNHAVLLVGYGTDSASGMDYWIVK 426
Query: 180 NSWGNGWGENGYFRIRRGNDECGIESLGVASEPI 281
NSWG GWGENGYFRIRRG DEC IES+ VA+ PI
Sbjct: 427 NSWGTGWGENGYFRIRRGTDECAIESIAVAATPI 460
>sp|Q60HG6|CATC_MACFA Dipeptidyl-peptidase I precursor (DPP-I) (DPPI) (Cathepsin C)
(Cathepsin J) (Dipeptidyl transferase) [Contains:
Dipeptidyl-peptidase I exclusion domain chain;
Dipeptidyl-peptidase I heavy chain; Dipeptidyl-peptidase
I light chain]
Length = 463
Score = 129 bits (323), Expect = 3e-30
Identities = 60/94 (63%), Positives = 71/94 (75%), Gaps = 1/94 (1%)
Frame = +3
Query: 3 FEVYDDFMSYSGGVYHHNFGTRKLTTSKFGFNPFELTNHAVLVVGYG-ETSSGEKFWIVK 179
FEVYDDF+ Y G+YHH T + FNPFELTNHAVL+VGYG +++SG +WIVK
Sbjct: 374 FEVYDDFLHYQNGIYHH-------TGLRDPFNPFELTNHAVLLVGYGTDSASGMDYWIVK 426
Query: 180 NSWGNGWGENGYFRIRRGNDECGIESLGVASEPI 281
NSWG WGE+GYFRIRRG DEC IES+ VA+ PI
Sbjct: 427 NSWGTSWGEDGYFRIRRGTDECAIESIAVAATPI 460
>sp|Q26563|CATC_SCHMA Cathepsin C precursor
Length = 454
Score = 127 bits (318), Expect = 1e-29
Identities = 59/95 (62%), Positives = 69/95 (72%), Gaps = 1/95 (1%)
Frame = +3
Query: 3 FEVYDDFMSYSGGVYHHNFGTRKLTTSKFGFNPFELTNHAVLVVGYG-ETSSGEKFWIVK 179
FEVY+DF Y G+YHH + T + FNPFELTNHAVL+VGYG + SGE +W VK
Sbjct: 364 FEVYEDFQFYKEGIYHHT----TVQTDHYNFNPFELTNHAVLLVGYGVDKLSGEPYWKVK 419
Query: 180 NSWGNGWGENGYFRIRRGNDECGIESLGVASEPIL 284
NSWG WGE GYFRI RG DECG+ESLGV +P+L
Sbjct: 420 NSWGVEWGEQGYFRILRGTDECGVESLGVRFDPVL 454
>sp|O97578|CATC_CANFA Dipeptidyl-peptidase I precursor (DPP-I) (DPPI) (Cathepsin C)
(Cathepsin J) (Dipeptidyl transferase) [Contains:
Dipeptidyl-peptidase I exclusion domain chain;
Dipeptidyl-peptidase I heavy chain 1;
Dipeptidyl-peptidase I heavy chain 2;
Dipeptidyl-peptidase I heavy chain 3;
Dipeptidyl-peptidase I heavy chain 4;
Dipeptidyl-peptidase I light chain]
Length = 435
Score = 124 bits (312), Expect = 5e-29
Identities = 59/94 (62%), Positives = 71/94 (75%), Gaps = 1/94 (1%)
Frame = +3
Query: 3 FEVYDDFMSYSGGVYHHNFGTRKLTTSKFGFNPFELTNHAVLVVGYG-ETSSGEKFWIVK 179
FEVYDDF Y G+Y+H T + FNPFELTNHAVL+VGYG +++SG +WIVK
Sbjct: 346 FEVYDDFFHYQKGIYYH-------TGLRDPFNPFELTNHAVLLVGYGTDSASGMDYWIVK 398
Query: 180 NSWGNGWGENGYFRIRRGNDECGIESLGVASEPI 281
NSWG+ WGE+GYFRIRRG DEC IES+ VA+ PI
Sbjct: 399 NSWGSRWGEDGYFRIRRGTDECAIESIAVAATPI 432
>sp|P97821|CATC_MOUSE Dipeptidyl-peptidase I precursor (DPP-I) (DPPI) (Cathepsin C)
(Cathepsin J) (Dipeptidyl transferase) [Contains:
Dipeptidyl-peptidase I exclusion domain chain;
Dipeptidyl-peptidase I heavy chain; Dipeptidyl-peptidase
I light chain]
Length = 462
Score = 122 bits (306), Expect = 3e-28
Identities = 57/94 (60%), Positives = 70/94 (74%), Gaps = 1/94 (1%)
Frame = +3
Query: 3 FEVYDDFMSYSGGVYHHNFGTRKLTTSKFGFNPFELTNHAVLVVGYG-ETSSGEKFWIVK 179
FEV+DDF+ Y G+YHH T FNPFELTNHAVL+VGYG + +G ++WI+K
Sbjct: 373 FEVHDDFLHYHSGIYHH-------TGLSDPFNPFELTNHAVLLVGYGRDPVTGIEYWIIK 425
Query: 180 NSWGNGWGENGYFRIRRGNDECGIESLGVASEPI 281
NSWG+ WGE+GYFRIRRG DEC IES+ VA+ PI
Sbjct: 426 NSWGSNWGESGYFRIRRGTDECAIESIAVAAIPI 459
>sp|P80067|CATC_RAT Dipeptidyl-peptidase I precursor (DPP-I) (DPPI) (Cathepsin C)
(Cathepsin J) (Dipeptidyl transferase) [Contains:
Dipeptidyl-peptidase I exclusion domain chain;
Dipeptidyl-peptidase I heavy chain; Dipeptidyl-peptidase
I light chain]
Length = 462
Score = 120 bits (300), Expect = 1e-27
Identities = 57/94 (60%), Positives = 69/94 (73%), Gaps = 1/94 (1%)
Frame = +3
Query: 3 FEVYDDFMSYSGGVYHHNFGTRKLTTSKFGFNPFELTNHAVLVVGYGETS-SGEKFWIVK 179
FEV+DDF+ Y G+YHH T FNPFELTNHAVL+VGYG+ +G +WIVK
Sbjct: 373 FEVHDDFLHYHSGIYHH-------TGLSDPFNPFELTNHAVLLVGYGKDPVTGLDYWIVK 425
Query: 180 NSWGNGWGENGYFRIRRGNDECGIESLGVASEPI 281
NSWG+ WGE+GYFRIRRG DEC IES+ +A+ PI
Sbjct: 426 NSWGSQWGESGYFRIRRGTDECAIESIAMAAIPI 459
>sp|P25807|CPR1_CAEEL Gut-specific cysteine proteinase precursor
Length = 329
Score = 87.0 bits (214), Expect = 1e-17
Identities = 42/91 (46%), Positives = 56/91 (61%)
Frame = +3
Query: 3 FEVYDDFMSYSGGVYHHNFGTRKLTTSKFGFNPFELTNHAVLVVGYGETSSGEKFWIVKN 182
F VY+DF Y GVY H T K+ L HA+ ++G+G T SG +W+V N
Sbjct: 250 FSVYEDFYKYKSGVYKH-------TAGKY------LGGHAIKIIGWG-TESGSPYWLVAN 295
Query: 183 SWGNGWGENGYFRIRRGNDECGIESLGVASE 275
SWG WGE+G+F+I RG+D+CGIES VA +
Sbjct: 296 SWGVNWGESGFFKIYRGDDQCGIESAVVAGK 326
>sp|P92131|CATB1_GIALA Cathepsin B-like CP1 precursor (Cathepsin B-like protease B1)
Length = 303
Score = 86.7 bits (213), Expect = 2e-17
Identities = 43/82 (52%), Positives = 49/82 (59%)
Frame = +3
Query: 9 VYDDFMSYSGGVYHHNFGTRKLTTSKFGFNPFELTNHAVLVVGYGETSSGEKFWIVKNSW 188
VY D Y GVY H +GT L GF HA+ +VGYG T G +WI+KNSW
Sbjct: 225 VYADLSYYESGVYKHTYGTINL-----GF-------HALEIVGYGTTDDGTDYWIIKNSW 272
Query: 189 GNGWGENGYFRIRRGNDECGIE 254
G WGENGYFRI RG +EC IE
Sbjct: 273 GPDWGENGYFRIVRGVNECRIE 294
>sp|P92133|CATB3_GIALA Cathepsin B-like CP3 precursor (Cathepsin B-like protease B3)
Length = 299
Score = 85.5 bits (210), Expect = 3e-17
Identities = 41/84 (48%), Positives = 48/84 (57%)
Frame = +3
Query: 3 FEVYDDFMSYSGGVYHHNFGTRKLTTSKFGFNPFELTNHAVLVVGYGETSSGEKFWIVKN 182
F VY DFM Y GVY H +G + HAV +VGYG G +WI+KN
Sbjct: 219 FTVYSDFMYYESGVYQHTYGRVE-------------GGHAVDMVGYGTDDDGVDYWIIKN 265
Query: 183 SWGNGWGENGYFRIRRGNDECGIE 254
SWG WGE+GYFRI R +ECGIE
Sbjct: 266 SWGPDWGEDGYFRIIRMTNECGIE 289
>sp|P43508|CPR4_CAEEL Cathepsin B-like cysteine proteinase 4 precursor (Cysteine
protease-related 4)
Length = 335
Score = 84.0 bits (206), Expect = 1e-16
Identities = 42/92 (45%), Positives = 51/92 (55%)
Frame = +3
Query: 3 FEVYDDFMSYSGGVYHHNFGTRKLTTSKFGFNPFELTNHAVLVVGYGETSSGEKFWIVKN 182
F VY+DF Y GVY H G EL HA+ ++G+G T +G +W+V N
Sbjct: 256 FTVYEDFYQYKTGVYVHTTGQ-------------ELGGHAIRILGWG-TDNGTPYWLVAN 301
Query: 183 SWGNGWGENGYFRIRRGNDECGIESLGVASEP 278
SW WGENGYFRI RG +ECGIE V P
Sbjct: 302 SWNVNWGENGYFRIIRGTNECGIEHAVVGGVP 333
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 41,413,840
Number of Sequences: 369166
Number of extensions: 857641
Number of successful extensions: 2662
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 2455
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 2506
length of database: 68,354,980
effective HSP length: 84
effective length of database: 52,837,240
effective search space used: 1690791680
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)