Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_018_N11
(400 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P53634|CATC_HUMAN Dipeptidyl-peptidase I precursor (DPP-... 152 2e-37
sp|Q60HG6|CATC_MACFA Dipeptidyl-peptidase I precursor (DPP-... 149 3e-36
sp|Q26563|CATC_SCHMA Cathepsin C precursor 148 4e-36
sp|O97578|CATC_CANFA Dipeptidyl-peptidase I precursor (DPP-... 147 1e-35
sp|P97821|CATC_MOUSE Dipeptidyl-peptidase I precursor (DPP-... 143 1e-34
sp|P80067|CATC_RAT Dipeptidyl-peptidase I precursor (DPP-I)... 141 5e-34
sp|P25807|CPR1_CAEEL Gut-specific cysteine proteinase precu... 97 9e-21
sp|P43510|CPR6_CAEEL Cathepsin B-like cysteine proteinase 6... 95 6e-20
sp|P43508|CPR4_CAEEL Cathepsin B-like cysteine proteinase 4... 94 1e-19
sp|P92133|CATB3_GIALA Cathepsin B-like CP3 precursor (Cathe... 94 1e-19
>sp|P53634|CATC_HUMAN Dipeptidyl-peptidase I precursor (DPP-I) (DPPI) (Cathepsin C)
(Cathepsin J) (Dipeptidyl transferase) [Contains:
Dipeptidyl-peptidase I exclusion domain chain;
Dipeptidyl-peptidase I heavy chain; Dipeptidyl-peptidase
I light chain]
Length = 463
Score = 152 bits (385), Expect = 2e-37
Identities = 72/111 (64%), Positives = 86/111 (77%), Gaps = 1/111 (0%)
Frame = +3
Query: 3 EPLMRMELVRNGPIAVGFEVYDDFMSYSGGVYHHNFGTRKLTTSKFGFNPFELTNHAVLV 182
E LM++ELV +GP+AV FEVYDDF+ Y G+YHH T + FNPFELTNHAVL+
Sbjct: 357 EALMKLELVHHGPMAVAFEVYDDFLHYKKGIYHH-------TGLRDPFNPFELTNHAVLL 409
Query: 183 VGYG-ETSSGEKFWIVKNSWGNGWGENGYFRIRRGNDECGIESLGVASEPI 332
VGYG +++SG +WIVKNSWG GWGENGYFRIRRG DEC IES+ VA+ PI
Sbjct: 410 VGYGTDSASGMDYWIVKNSWGTGWGENGYFRIRRGTDECAIESIAVAATPI 460
>sp|Q60HG6|CATC_MACFA Dipeptidyl-peptidase I precursor (DPP-I) (DPPI) (Cathepsin C)
(Cathepsin J) (Dipeptidyl transferase) [Contains:
Dipeptidyl-peptidase I exclusion domain chain;
Dipeptidyl-peptidase I heavy chain; Dipeptidyl-peptidase
I light chain]
Length = 463
Score = 149 bits (375), Expect = 3e-36
Identities = 70/111 (63%), Positives = 85/111 (76%), Gaps = 1/111 (0%)
Frame = +3
Query: 3 EPLMRMELVRNGPIAVGFEVYDDFMSYSGGVYHHNFGTRKLTTSKFGFNPFELTNHAVLV 182
E LM++ELV +GP+AV FEVYDDF+ Y G+YHH T + FNPFELTNHAVL+
Sbjct: 357 EALMKLELVYHGPLAVAFEVYDDFLHYQNGIYHH-------TGLRDPFNPFELTNHAVLL 409
Query: 183 VGYG-ETSSGEKFWIVKNSWGNGWGENGYFRIRRGNDECGIESLGVASEPI 332
VGYG +++SG +WIVKNSWG WGE+GYFRIRRG DEC IES+ VA+ PI
Sbjct: 410 VGYGTDSASGMDYWIVKNSWGTSWGEDGYFRIRRGTDECAIESIAVAATPI 460
>sp|Q26563|CATC_SCHMA Cathepsin C precursor
Length = 454
Score = 148 bits (373), Expect = 4e-36
Identities = 69/112 (61%), Positives = 82/112 (73%), Gaps = 1/112 (0%)
Frame = +3
Query: 3 EPLMRMELVRNGPIAVGFEVYDDFMSYSGGVYHHNFGTRKLTTSKFGFNPFELTNHAVLV 182
E LM++EL+ NGP VGFEVY+DF Y G+YHH + T + FNPFELTNHAVL+
Sbjct: 347 EKLMQLELISNGPFPVGFEVYEDFQFYKEGIYHHT----TVQTDHYNFNPFELTNHAVLL 402
Query: 183 VGYG-ETSSGEKFWIVKNSWGNGWGENGYFRIRRGNDECGIESLGVASEPIL 335
VGYG + SGE +W VKNSWG WGE GYFRI RG DECG+ESLGV +P+L
Sbjct: 403 VGYGVDKLSGEPYWKVKNSWGVEWGEQGYFRILRGTDECGVESLGVRFDPVL 454
>sp|O97578|CATC_CANFA Dipeptidyl-peptidase I precursor (DPP-I) (DPPI) (Cathepsin C)
(Cathepsin J) (Dipeptidyl transferase) [Contains:
Dipeptidyl-peptidase I exclusion domain chain;
Dipeptidyl-peptidase I heavy chain 1;
Dipeptidyl-peptidase I heavy chain 2;
Dipeptidyl-peptidase I heavy chain 3;
Dipeptidyl-peptidase I heavy chain 4;
Dipeptidyl-peptidase I light chain]
Length = 435
Score = 147 bits (370), Expect = 1e-35
Identities = 70/111 (63%), Positives = 86/111 (77%), Gaps = 1/111 (0%)
Frame = +3
Query: 3 EPLMRMELVRNGPIAVGFEVYDDFMSYSGGVYHHNFGTRKLTTSKFGFNPFELTNHAVLV 182
E LM++ELVR+GP+AV FEVYDDF Y G+Y+H T + FNPFELTNHAVL+
Sbjct: 329 EALMKLELVRHGPMAVAFEVYDDFFHYQKGIYYH-------TGLRDPFNPFELTNHAVLL 381
Query: 183 VGYG-ETSSGEKFWIVKNSWGNGWGENGYFRIRRGNDECGIESLGVASEPI 332
VGYG +++SG +WIVKNSWG+ WGE+GYFRIRRG DEC IES+ VA+ PI
Sbjct: 382 VGYGTDSASGMDYWIVKNSWGSRWGEDGYFRIRRGTDECAIESIAVAATPI 432
>sp|P97821|CATC_MOUSE Dipeptidyl-peptidase I precursor (DPP-I) (DPPI) (Cathepsin C)
(Cathepsin J) (Dipeptidyl transferase) [Contains:
Dipeptidyl-peptidase I exclusion domain chain;
Dipeptidyl-peptidase I heavy chain; Dipeptidyl-peptidase
I light chain]
Length = 462
Score = 143 bits (361), Expect = 1e-34
Identities = 67/111 (60%), Positives = 85/111 (76%), Gaps = 1/111 (0%)
Frame = +3
Query: 3 EPLMRMELVRNGPIAVGFEVYDDFMSYSGGVYHHNFGTRKLTTSKFGFNPFELTNHAVLV 182
E LM++ELV++GP+AV FEV+DDF+ Y G+YHH T FNPFELTNHAVL+
Sbjct: 356 EALMKLELVKHGPMAVAFEVHDDFLHYHSGIYHH-------TGLSDPFNPFELTNHAVLL 408
Query: 183 VGYG-ETSSGEKFWIVKNSWGNGWGENGYFRIRRGNDECGIESLGVASEPI 332
VGYG + +G ++WI+KNSWG+ WGE+GYFRIRRG DEC IES+ VA+ PI
Sbjct: 409 VGYGRDPVTGIEYWIIKNSWGSNWGESGYFRIRRGTDECAIESIAVAAIPI 459
>sp|P80067|CATC_RAT Dipeptidyl-peptidase I precursor (DPP-I) (DPPI) (Cathepsin C)
(Cathepsin J) (Dipeptidyl transferase) [Contains:
Dipeptidyl-peptidase I exclusion domain chain;
Dipeptidyl-peptidase I heavy chain; Dipeptidyl-peptidase
I light chain]
Length = 462
Score = 141 bits (355), Expect = 5e-34
Identities = 67/111 (60%), Positives = 84/111 (75%), Gaps = 1/111 (0%)
Frame = +3
Query: 3 EPLMRMELVRNGPIAVGFEVYDDFMSYSGGVYHHNFGTRKLTTSKFGFNPFELTNHAVLV 182
E LM++ELV++GP+AV FEV+DDF+ Y G+YHH T FNPFELTNHAVL+
Sbjct: 356 EALMKLELVKHGPMAVAFEVHDDFLHYHSGIYHH-------TGLSDPFNPFELTNHAVLL 408
Query: 183 VGYGETS-SGEKFWIVKNSWGNGWGENGYFRIRRGNDECGIESLGVASEPI 332
VGYG+ +G +WIVKNSWG+ WGE+GYFRIRRG DEC IES+ +A+ PI
Sbjct: 409 VGYGKDPVTGLDYWIVKNSWGSQWGESGYFRIRRGTDECAIESIAMAAIPI 459
>sp|P25807|CPR1_CAEEL Gut-specific cysteine proteinase precursor
Length = 329
Score = 97.4 bits (241), Expect = 9e-21
Identities = 46/105 (43%), Positives = 64/105 (60%)
Frame = +3
Query: 12 MRMELVRNGPIAVGFEVYDDFMSYSGGVYHHNFGTRKLTTSKFGFNPFELTNHAVLVVGY 191
++ E+ NGP+ F VY+DF Y GVY H T K+ L HA+ ++G+
Sbjct: 236 IQAEIYANGPVEAAFSVYEDFYKYKSGVYKH-------TAGKY------LGGHAIKIIGW 282
Query: 192 GETSSGEKFWIVKNSWGNGWGENGYFRIRRGNDECGIESLGVASE 326
G T SG +W+V NSWG WGE+G+F+I RG+D+CGIES VA +
Sbjct: 283 G-TESGSPYWLVANSWGVNWGESGFFKIYRGDDQCGIESAVVAGK 326
>sp|P43510|CPR6_CAEEL Cathepsin B-like cysteine proteinase 6 precursor (Cysteine
protease-related 6)
Length = 379
Score = 94.7 bits (234), Expect = 6e-20
Identities = 51/112 (45%), Positives = 66/112 (58%)
Frame = +3
Query: 12 MRMELVRNGPIAVGFEVYDDFMSYSGGVYHHNFGTRKLTTSKFGFNPFELTNHAVLVVGY 191
++ EL+ +GP+ + FEVY+DF++Y GGVY H G K G HAV ++G+
Sbjct: 266 IQKELMTHGPLEIAFEVYEDFLNYDGGVYVHTGG-------KLG------GGHAVKLIGW 312
Query: 192 GETSSGEKFWIVKNSWGNGWGENGYFRIRRGNDECGIESLGVASEPIL*MLT 347
G G +W V NSW WGE+G+FRI RG DECGIES V P L LT
Sbjct: 313 G-IDDGIPYWTVANSWNTDWGEDGFFRILRGVDECGIESGVVGGIPKLNSLT 363
>sp|P43508|CPR4_CAEEL Cathepsin B-like cysteine proteinase 4 precursor (Cysteine
protease-related 4)
Length = 335
Score = 94.0 bits (232), Expect = 1e-19
Identities = 45/106 (42%), Positives = 60/106 (56%)
Frame = +3
Query: 12 MRMELVRNGPIAVGFEVYDDFMSYSGGVYHHNFGTRKLTTSKFGFNPFELTNHAVLVVGY 191
++ E++ +GP+ F VY+DF Y GVY H G EL HA+ ++G+
Sbjct: 242 IQAEIIAHGPVEAAFTVYEDFYQYKTGVYVHTTGQ-------------ELGGHAIRILGW 288
Query: 192 GETSSGEKFWIVKNSWGNGWGENGYFRIRRGNDECGIESLGVASEP 329
G T +G +W+V NSW WGENGYFRI RG +ECGIE V P
Sbjct: 289 G-TDNGTPYWLVANSWNVNWGENGYFRIIRGTNECGIEHAVVGGVP 333
>sp|P92133|CATB3_GIALA Cathepsin B-like CP3 precursor (Cathepsin B-like protease B3)
Length = 299
Score = 93.6 bits (231), Expect = 1e-19
Identities = 45/100 (45%), Positives = 54/100 (54%)
Frame = +3
Query: 6 PLMRMELVRNGPIAVGFEVYDDFMSYSGGVYHHNFGTRKLTTSKFGFNPFELTNHAVLVV 185
P + L GP+ F VY DFM Y GVY H +G + HAV +V
Sbjct: 203 PAIMKALATGGPLQTAFTVYSDFMYYESGVYQHTYGRVE-------------GGHAVDMV 249
Query: 186 GYGETSSGEKFWIVKNSWGNGWGENGYFRIRRGNDECGIE 305
GYG G +WI+KNSWG WGE+GYFRI R +ECGIE
Sbjct: 250 GYGTDDDGVDYWIIKNSWGPDWGEDGYFRIIRMTNECGIE 289
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 48,274,191
Number of Sequences: 369166
Number of extensions: 1011118
Number of successful extensions: 2889
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 2666
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 2719
length of database: 68,354,980
effective HSP length: 98
effective length of database: 50,250,950
effective search space used: 1708532300
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)