Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_022_C11
(689 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P53634|CATC_HUMAN Dipeptidyl-peptidase I precursor (DPP-... 235 9e-62
sp|P97821|CATC_MOUSE Dipeptidyl-peptidase I precursor (DPP-... 233 5e-61
sp|Q60HG6|CATC_MACFA Dipeptidyl-peptidase I precursor (DPP-... 228 9e-60
sp|P80067|CATC_RAT Dipeptidyl-peptidase I precursor (DPP-I)... 226 3e-59
sp|O97578|CATC_CANFA Dipeptidyl-peptidase I precursor (DPP-... 223 4e-58
sp|Q26563|CATC_SCHMA Cathepsin C precursor 170 4e-42
sp|P82473|CPGP1_ZINOF Cysteine proteinase GP-I 80 7e-15
sp|O10364|CATV_NPVOP Viral cathepsin (V-cath) (Cysteine pro... 79 9e-15
sp|P41715|CATV_NPVCF Viral cathepsin (V-cath) (Cysteine pro... 77 3e-14
sp|Q80LP4|CATV_NPVAH Viral cathepsin (V-cath) (Cysteine pro... 77 6e-14
>sp|P53634|CATC_HUMAN Dipeptidyl-peptidase I precursor (DPP-I) (DPPI) (Cathepsin C)
(Cathepsin J) (Dipeptidyl transferase) [Contains:
Dipeptidyl-peptidase I exclusion domain chain;
Dipeptidyl-peptidase I heavy chain; Dipeptidyl-peptidase
I light chain]
Length = 463
Score = 235 bits (599), Expect = 9e-62
Identities = 113/233 (48%), Positives = 145/233 (62%), Gaps = 9/233 (3%)
Frame = +3
Query: 18 SYCDRLQPSWFHDVLIRQWQCFKAQRTTTLKE---------KNNVLPHSNIFALTSLRYG 170
+YC+ W HDVL R W CF ++ T E KN+ +SN Y
Sbjct: 116 TYCNETMTGWVHDVLGRNWACFTGKKVGTASENVYVNTAHLKNSQEKYSNRL------YK 169
Query: 171 SQKRIVDKINLENNGWTAKDYPEFHEKTLYEVINMAGGSRSKLERPKPAPITKSILDSVK 350
V IN WTA Y E+ TL ++I +GG K+ RPKPAP+T I +
Sbjct: 170 YDHNFVKAINAIQKSWTATTYMEYETLTLGDMIRRSGGHSRKIPRPKPAPLTAEIQQKIL 229
Query: 351 LIPKSFDWRNVNGLNYVSPVRNQGGCGSCYSFASAGMLEARYRIRSNNTVRPILSPQDVV 530
+P S+DWRNV+G+N+VSPVRNQ CGSCYSFAS GMLEAR RI +NN+ PILSPQ+VV
Sbjct: 230 HLPTSWDWRNVHGINFVSPVRNQASCGSCYSFASMGMLEARIRILTNNSQTPILSPQEVV 289
Query: 531 ECSPYSQGCDGGFPYLIAGKFAEDFGMAQESCNPYKGMNGKCSTTKDCKRYFA 689
CS Y+QGC+GGFPYLIAGK+A+DFG+ +E+C PY G + C +DC RY++
Sbjct: 290 SCSQYAQGCEGGFPYLIAGKYAQDFGLVEEACFPYTGTDSPCKMKEDCFRYYS 342
>sp|P97821|CATC_MOUSE Dipeptidyl-peptidase I precursor (DPP-I) (DPPI) (Cathepsin C)
(Cathepsin J) (Dipeptidyl transferase) [Contains:
Dipeptidyl-peptidase I exclusion domain chain;
Dipeptidyl-peptidase I heavy chain; Dipeptidyl-peptidase
I light chain]
Length = 462
Score = 233 bits (593), Expect = 5e-61
Identities = 115/232 (49%), Positives = 148/232 (63%), Gaps = 7/232 (3%)
Frame = +3
Query: 15 ISYCDRLQPSWFHDVLIRQWQCFKAQRTTTLKEKNNVLPHSNIFALTSLR-------YGS 173
ISYC W HDVL R W CF ++ + EK N+ N L L+ Y
Sbjct: 115 ISYCHETMTGWVHDVLGRNWACFVGKKVESHIEKVNM----NAAHLGGLQERYSERLYTH 170
Query: 174 QKRIVDKINLENNGWTAKDYPEFHEKTLYEVINMAGGSRSKLERPKPAPITKSILDSVKL 353
V IN WTA Y E+ + +L ++I +G S+ ++ RPKPAP+T I +
Sbjct: 171 NHNFVKAINTVQKSWTATAYKEYEKMSLRDLIRRSGHSQ-RIPRPKPAPMTDEIQQQILN 229
Query: 354 IPKSFDWRNVNGLNYVSPVRNQGGCGSCYSFASAGMLEARYRIRSNNTVRPILSPQDVVE 533
+P+S+DWRNV G+NYVSPVRNQ CGSCYSFAS GMLEAR RI +NN+ PILSPQ+VV
Sbjct: 230 LPESWDWRNVQGVNYVSPVRNQESCGSCYSFASMGMLEARIRILTNNSQTPILSPQEVVS 289
Query: 534 CSPYSQGCDGGFPYLIAGKFAEDFGMAQESCNPYKGMNGKCSTTKDCKRYFA 689
CSPY+QGCDGGFPYLIAGK+A+DFG+ +ESC PY + C ++C RY++
Sbjct: 290 CSPYAQGCDGGFPYLIAGKYAQDFGVVEESCFPYTAKDSPCKpreNCLRYYS 341
>sp|Q60HG6|CATC_MACFA Dipeptidyl-peptidase I precursor (DPP-I) (DPPI) (Cathepsin C)
(Cathepsin J) (Dipeptidyl transferase) [Contains:
Dipeptidyl-peptidase I exclusion domain chain;
Dipeptidyl-peptidase I heavy chain; Dipeptidyl-peptidase
I light chain]
Length = 463
Score = 228 bits (582), Expect = 9e-60
Identities = 110/232 (47%), Positives = 141/232 (60%), Gaps = 9/232 (3%)
Frame = +3
Query: 21 YCDRLQPSWFHDVLIRQWQCFKAQRTTTLKE---------KNNVLPHSNIFALTSLRYGS 173
YC+ W HDVL R W CF ++ T E KN+ +SN Y
Sbjct: 117 YCNETMTGWVHDVLGRNWACFTGKKVGTASENVYVNTAHLKNSQEKYSNRL------YKY 170
Query: 174 QKRIVDKINLENNGWTAKDYPEFHEKTLYEVINMAGGSRSKLERPKPAPITKSILDSVKL 353
V IN WTA Y E+ TL ++I +GG K+ RPKP P+T I +
Sbjct: 171 DHNFVKAINAIQKSWTATTYMEYETLTLGDMIKRSGGHSRKIPRPKPTPLTAEIQQKILH 230
Query: 354 IPKSFDWRNVNGLNYVSPVRNQGGCGSCYSFASAGMLEARYRIRSNNTVRPILSPQDVVE 533
+P S+DWRNV+G+N+VSPVRNQ CGSCYSFAS GMLEAR RI +NN+ PILS Q+VV
Sbjct: 231 LPTSWDWRNVHGINFVSPVRNQASCGSCYSFASVGMLEARIRILTNNSQTPILSSQEVVS 290
Query: 534 CSPYSQGCDGGFPYLIAGKFAEDFGMAQESCNPYKGMNGKCSTTKDCKRYFA 689
CS Y+QGC+GGFPYL AGK+A+DFG+ +E+C PY G + C +DC RY++
Sbjct: 291 CSQYAQGCEGGFPYLTAGKYAQDFGLVEEACFPYTGTDSPCKMKEDCFRYYS 342
>sp|P80067|CATC_RAT Dipeptidyl-peptidase I precursor (DPP-I) (DPPI) (Cathepsin C)
(Cathepsin J) (Dipeptidyl transferase) [Contains:
Dipeptidyl-peptidase I exclusion domain chain;
Dipeptidyl-peptidase I heavy chain; Dipeptidyl-peptidase
I light chain]
Length = 462
Score = 226 bits (577), Expect = 3e-59
Identities = 111/232 (47%), Positives = 144/232 (62%), Gaps = 7/232 (3%)
Frame = +3
Query: 15 ISYCDRLQPSWFHDVLIRQWQCFKAQRTTTLKEKNNVLPHSNIFALTSLR-------YGS 173
ISYC W HD L R W CF ++ EK V N+ L L+ Y
Sbjct: 115 ISYCHETMTGWVHDYLGRNWACFVGKKMANHSEKVYV----NVAHLGGLQEKYSERLYSH 170
Query: 174 QKRIVDKINLENNGWTAKDYPEFHEKTLYEVINMAGGSRSKLERPKPAPITKSILDSVKL 353
V IN WTA Y + + ++ ++I +G S ++ RPKPAPIT I +
Sbjct: 171 HHNFVKAINSVQKSWTATTYRRYEKLSIRDLIRRSGHS-GRILRPKPAPITDEIQQQILS 229
Query: 354 IPKSFDWRNVNGLNYVSPVRNQGGCGSCYSFASAGMLEARYRIRSNNTVRPILSPQDVVE 533
+P+S+DWRNV G+N+VSPVRNQ CGSCYSFAS GMLEAR RI +NN+ PILSPQ+VV
Sbjct: 230 LPESWDWRNVRGINFVSPVRNQESCGSCYSFASIGMLEARIRILTNNSQTPILSPQEVVS 289
Query: 534 CSPYSQGCDGGFPYLIAGKFAEDFGMAQESCNPYKGMNGKCSTTKDCKRYFA 689
CSPY+QGCDGGFPYLIAGK+A+DFG+ +E+C PY + C ++C RY++
Sbjct: 290 CSPYAQGCDGGFPYLIAGKYAQDFGVVEENCFPYTATDAPCKPKENCLRYYS 341
>sp|O97578|CATC_CANFA Dipeptidyl-peptidase I precursor (DPP-I) (DPPI) (Cathepsin C)
(Cathepsin J) (Dipeptidyl transferase) [Contains:
Dipeptidyl-peptidase I exclusion domain chain;
Dipeptidyl-peptidase I heavy chain 1;
Dipeptidyl-peptidase I heavy chain 2;
Dipeptidyl-peptidase I heavy chain 3;
Dipeptidyl-peptidase I heavy chain 4;
Dipeptidyl-peptidase I light chain]
Length = 435
Score = 223 bits (568), Expect = 4e-58
Identities = 111/231 (48%), Positives = 139/231 (60%), Gaps = 7/231 (3%)
Frame = +3
Query: 18 SYCDRLQPSWFHDVLIRQWQCFKAQRTTTLKEKNNV-------LPHSNIFALTSLRYGSQ 176
SYC+ W HDVL R W CF + T EK V L +N L Y
Sbjct: 91 SYCNETMTGWVHDVLGRNWACFTGTKMGTTSEKAKVNTKHIERLQENNSNRLYKYNY--- 147
Query: 177 KRIVDKINLENNGWTAKDYPEFHEKTLYEVINMAGGSRSKLERPKPAPITKSILDSVKLI 356
V IN WTA Y E+ TL +++ GG K+ RPKP P+T I + + +
Sbjct: 148 -EFVKAINTIQKSWTATRYIEYETLTLRDMMTRVGGR--KIPRPKPTPLTAEIHEEISRL 204
Query: 357 PKSFDWRNVNGLNYVSPVRNQGGCGSCYSFASAGMLEARYRIRSNNTVRPILSPQDVVEC 536
P S+DWRNV G N+VSPVRNQ CGSCY+FAS MLEAR RI +NNT PILSPQ++V C
Sbjct: 205 PTSWDWRNVRGTNFVSPVRNQASCGSCYAFASTAMLEARIRILTNNTQTPILSPQEIVSC 264
Query: 537 SPYSQGCDGGFPYLIAGKFAEDFGMAQESCNPYKGMNGKCSTTKDCKRYFA 689
S Y+QGC+GGFPYLIAGK+A+DFG+ +E+C PY G + C DC RY++
Sbjct: 265 SQYAQGCEGGFPYLIAGKYAQDFGLVEEACFPYAGSDSPCK-PNDCFRYYS 314
>sp|Q26563|CATC_SCHMA Cathepsin C precursor
Length = 454
Score = 170 bits (430), Expect = 4e-42
Identities = 96/228 (42%), Positives = 129/228 (56%), Gaps = 7/228 (3%)
Frame = +3
Query: 24 CDRLQPSWFHDVLIRQWQCFKAQRTTTLKEKNNVLPHSNIFALTSLRYGSQKRIVDKINL 203
C + P W HD LI + K N L S F T Y V KIN
Sbjct: 107 CHKSMPMWTHDTLIDSGSVCSGKIGVHDKFHINKLFGSKSFGRTL--YHINPSFVGKINA 164
Query: 204 ENNGWTAKDYPEFHEKTLYEVINMAGGSRSKLERP----KPAPITKSILDSVKLIPKSFD 371
W + YPE + T+ E+ N AGG +S + RP + P +K ++ +P FD
Sbjct: 165 HQKSWRGEIYPELSKYTIDELRNRAGGVKSMVTRPSVLNRKTP-SKELISLTGNLPLEFD 223
Query: 372 WRNV--NGLNYVSPVRNQGGCGSCYSFASAGMLEARYRIRSNNTVRPILSPQDVVECSPY 545
W + + V+P+RNQG CGSCY+ SA LEAR R+ SN + +PILSPQ VV+CSPY
Sbjct: 224 WTSPPDGSRSPVTPIRNQGICGSCYASPSAAALEARIRLVSNFSEQPILSPQTVVDCSPY 283
Query: 546 SQGCDGGFPYLIAGKFAEDFGMAQESCNPYKGMN-GKCSTTKDCKRYF 686
S+GC+GGFP+LIAGK+ EDFG+ Q+ PY G + GKC+ +K+C RY+
Sbjct: 284 SEGCNGGFPFLIAGKYGEDFGLPQKIVIPYTGEDTGKCTVSKNCTRYY 331
>sp|P82473|CPGP1_ZINOF Cysteine proteinase GP-I
Length = 221
Score = 79.7 bits (195), Expect = 7e-15
Identities = 40/107 (37%), Positives = 60/107 (56%)
Frame = +3
Query: 351 LIPKSFDWRNVNGLNYVSPVRNQGGCGSCYSFASAGMLEARYRIRSNNTVRPILSPQDVV 530
++P S DWR V PV+NQGGCGSC++F + +E +I + + + LS Q +V
Sbjct: 2 VLPDSIDWREKGA---VVPVKNQGGCGSCWAFDAIAAVEGINQIVTGDLIS--LSEQQLV 56
Query: 531 ECSPYSQGCDGGFPYLIAGKFAEDFGMAQESCNPYKGMNGKCSTTKD 671
+CS + GC+GG+PY + G+ E PY G NG C T ++
Sbjct: 57 DCSTRNHGCEGGWPYRAFQYIINNGGINSEEHYPYTGTNGTCDTKEN 103
>sp|O10364|CATV_NPVOP Viral cathepsin (V-cath) (Cysteine proteinase) (CP)
Length = 324
Score = 79.3 bits (194), Expect = 9e-15
Identities = 42/117 (35%), Positives = 62/117 (52%), Gaps = 8/117 (6%)
Frame = +3
Query: 357 PKSFDWRNVNGLNYVSPVRNQGGCGSCYSFASAGMLEARYRIRSNNTVRPILSPQDVVEC 536
P FDWR N V+ V+NQG CG+C++FA+ G LE+++ I+ N + LS Q ++C
Sbjct: 114 PLEFDWRQ---FNKVTSVKNQGVCGACWAFATLGSLESQFAIKYNRLIN--LSEQQFIDC 168
Query: 537 SPYSQGCDGGFPYLIAGKFAEDFGMAQESCNPYKGMNGKCST--------TKDCKRY 683
+ GCDGG + E G+ ES PY+ NG+C + C+RY
Sbjct: 169 DRVNAGCDGGLLHTAFESAMEMGGVQMESDYPYETANGQCRINPNRFVVGVRSCRRY 225
>sp|P41715|CATV_NPVCF Viral cathepsin (V-cath) (Cysteine proteinase) (CP)
sp|O41479|CATV_NPVCD Viral cathepsin (V-cath) (Cysteine proteinase) (CP)
Length = 324
Score = 77.4 bits (189), Expect = 3e-14
Identities = 43/117 (36%), Positives = 60/117 (51%), Gaps = 8/117 (6%)
Frame = +3
Query: 357 PKSFDWRNVNGLNYVSPVRNQGGCGSCYSFASAGMLEARYRIRSNNTVRPILSPQDVVEC 536
P FDWR LN V+ V+NQG CG+C++FA+ G LE+++ I+ N + LS Q +++C
Sbjct: 114 PLEFDWRR---LNKVTSVKNQGMCGACWAFATLGSLESQFAIKHNQFIN--LSEQQLIDC 168
Query: 537 SPYSQGCDGGFPYLIAGKFAEDFGMAQESCNPYKGMNGKCST--------TKDCKRY 683
GCDGG + G+ ES PY+ NG C K C RY
Sbjct: 169 DFVDAGCDGGLLHTAFEAVMNMGGIQAESDYPYEANNGDCRANAAKFVVKVKKCYRY 225
>sp|Q80LP4|CATV_NPVAH Viral cathepsin (V-cath) (Cysteine proteinase) (CP)
Length = 337
Score = 76.6 bits (187), Expect = 6e-14
Identities = 41/118 (34%), Positives = 63/118 (53%), Gaps = 8/118 (6%)
Frame = +3
Query: 354 IPKSFDWRNVNGLNYVSPVRNQGGCGSCYSFASAGMLEARYRIRSNNTVRPILSPQDVVE 533
+P++FDWR VN N ++ V++QG CGSC++ A+ G LE Y I+ N + LS Q +++
Sbjct: 126 LPQNFDWR-VN--NKMTSVKDQGACGSCWAHAAVGTLETLYAIKHNYLIN--LSEQQLID 180
Query: 534 CSPYSQGCDGGFPYLIAGKFAEDFGMAQESCNPYKGMNGKCS--------TTKDCKRY 683
C + CDGG + + G+ +E PY+G G C + CKRY
Sbjct: 181 CDSANMACDGGLMHTAFEQLMNAGGLMEEIDYPYQGTKGVCKIDNKKFALSVSSCKRY 238
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 85,403,790
Number of Sequences: 369166
Number of extensions: 1786441
Number of successful extensions: 5024
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4609
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4823
length of database: 68,354,980
effective HSP length: 107
effective length of database: 48,588,335
effective search space used: 5927776870
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)