Planarian EST Database


Dr_sW_009_E09

BLASTX 2.2.12 [Aug-07-2005]

Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= Dr_sW_009_E09
         (898 letters)

Database: Non-redundant SwissProt sequences 
           184,735 sequences; 68,354,980 total letters



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

sp|P53634|CATC_HUMAN  Dipeptidyl-peptidase I precursor (DPP-...   320   3e-87
sp|Q60HG6|CATC_MACFA  Dipeptidyl-peptidase I precursor (DPP-...   312   9e-85
sp|P97821|CATC_MOUSE  Dipeptidyl-peptidase I precursor (DPP-...   310   3e-84
sp|O97578|CATC_CANFA  Dipeptidyl-peptidase I precursor (DPP-...   304   3e-82
sp|P80067|CATC_RAT  Dipeptidyl-peptidase I precursor (DPP-I)...   303   4e-82
sp|Q26563|CATC_SCHMA  Cathepsin C precursor                       273   5e-73
sp|P80884|ANAN_ANACO  Ananain precursor                           132   1e-30
sp|Q90686|CATK_CHICK  Cathepsin K precursor (JTAP-1)              123   6e-28
sp|O35186|CATK_RAT  Cathepsin K precursor                         123   8e-28
sp|P00786|CATH_RAT  Cathepsin H precursor (Cathepsin B3) (Ca...   122   1e-27
>sp|P53634|CATC_HUMAN Dipeptidyl-peptidase I precursor (DPP-I) (DPPI) (Cathepsin C)
           (Cathepsin J) (Dipeptidyl transferase) [Contains:
           Dipeptidyl-peptidase I exclusion domain chain;
           Dipeptidyl-peptidase I heavy chain; Dipeptidyl-peptidase
           I light chain]
          Length = 463

 Score =  320 bits (820), Expect = 3e-87
 Identities = 146/250 (58%), Positives = 187/250 (74%), Gaps = 1/250 (0%)
 Frame = +3

Query: 6   EFHEKTLYEVINMAGGSRSKLERPKPAPITKSILDSVKLIPKSFDWRNVNGVNYVSPVRN 185
           E+   TL ++I  +GG   K+ RPKPAP+T  I   +  +P S+DWRNV+G+N+VSPVRN
Sbjct: 192 EYETLTLGDMIRRSGGHSRKIPRPKPAPLTAEIQQKILHLPTSWDWRNVHGINFVSPVRN 251

Query: 186 QGGCGSCYSFASAGMLEARYRIRSNNTVRPILSPQDVVECSPYSQGCDGGFPYLIAGKFA 365
           Q  CGSCYSFAS GMLEAR RI +NN+  PILSPQ+VV CS Y+QGC+GGFPYLIAGK+A
Sbjct: 252 QASCGSCYSFASMGMLEARIRILTNNSQTPILSPQEVVSCSQYAQGCEGGFPYLIAGKYA 311

Query: 366 EDFGMAQESCNPYKGMNGKCSTTKDCKRYFATNYKYIGGYYGATNEPLMRMELVRNGPIA 545
           +DFG+ +E+C PY G +  C   +DC RY+++ Y Y+GG+YG  NE LM++ELV +GP+A
Sbjct: 312 QDFGLVEEACFPYTGTDSPCKMKEDCFRYYSSEYHYVGGFYGGCNEALMKLELVHHGPMA 371

Query: 546 VGFEVYDDFMSYSGGVYHHNFGTRKLTTSKFGFNPFELTNHAVLVVGYG-ETSSGEKFWI 722
           V FEVYDDF+ Y  G+YHH       T  +  FNPFELTNHAVL+VGYG +++SG  +WI
Sbjct: 372 VAFEVYDDFLHYKKGIYHH-------TGLRDPFNPFELTNHAVLLVGYGTDSASGMDYWI 424

Query: 723 VKNSWGNGMG 752
           VKNSWG G G
Sbjct: 425 VKNSWGTGWG 434

 Score = 57.8 bits (138), Expect = 4e-08
 Identities = 25/40 (62%), Positives = 31/40 (77%)
 Frame = +1

Query: 712 NFGLLKTVGVTGWGENGYFRIRRGNDECGIESLDVASEPI 831
           ++ ++K    TGWGENGYFRIRRG DEC IES+ VA+ PI
Sbjct: 421 DYWIVKNSWGTGWGENGYFRIRRGTDECAIESIAVAATPI 460
>sp|Q60HG6|CATC_MACFA Dipeptidyl-peptidase I precursor (DPP-I) (DPPI) (Cathepsin C)
           (Cathepsin J) (Dipeptidyl transferase) [Contains:
           Dipeptidyl-peptidase I exclusion domain chain;
           Dipeptidyl-peptidase I heavy chain; Dipeptidyl-peptidase
           I light chain]
          Length = 463

 Score =  312 bits (799), Expect = 9e-85
 Identities = 142/250 (56%), Positives = 183/250 (73%), Gaps = 1/250 (0%)
 Frame = +3

Query: 6   EFHEKTLYEVINMAGGSRSKLERPKPAPITKSILDSVKLIPKSFDWRNVNGVNYVSPVRN 185
           E+   TL ++I  +GG   K+ RPKP P+T  I   +  +P S+DWRNV+G+N+VSPVRN
Sbjct: 192 EYETLTLGDMIKRSGGHSRKIPRPKPTPLTAEIQQKILHLPTSWDWRNVHGINFVSPVRN 251

Query: 186 QGGCGSCYSFASAGMLEARYRIRSNNTVRPILSPQDVVECSPYSQGCDGGFPYLIAGKFA 365
           Q  CGSCYSFAS GMLEAR RI +NN+  PILS Q+VV CS Y+QGC+GGFPYL AGK+A
Sbjct: 252 QASCGSCYSFASVGMLEARIRILTNNSQTPILSSQEVVSCSQYAQGCEGGFPYLTAGKYA 311

Query: 366 EDFGMAQESCNPYKGMNGKCSTTKDCKRYFATNYKYIGGYYGATNEPLMRMELVRNGPIA 545
           +DFG+ +E+C PY G +  C   +DC RY+++ Y Y+GG+YG  NE LM++ELV +GP+A
Sbjct: 312 QDFGLVEEACFPYTGTDSPCKMKEDCFRYYSSEYHYVGGFYGGCNEALMKLELVYHGPLA 371

Query: 546 VGFEVYDDFMSYSGGVYHHNFGTRKLTTSKFGFNPFELTNHAVLVVGYG-ETSSGEKFWI 722
           V FEVYDDF+ Y  G+YHH       T  +  FNPFELTNHAVL+VGYG +++SG  +WI
Sbjct: 372 VAFEVYDDFLHYQNGIYHH-------TGLRDPFNPFELTNHAVLLVGYGTDSASGMDYWI 424

Query: 723 VKNSWGNGMG 752
           VKNSWG   G
Sbjct: 425 VKNSWGTSWG 434

 Score = 53.5 bits (127), Expect = 8e-07
 Identities = 23/40 (57%), Positives = 30/40 (75%)
 Frame = +1

Query: 712 NFGLLKTVGVTGWGENGYFRIRRGNDECGIESLDVASEPI 831
           ++ ++K    T WGE+GYFRIRRG DEC IES+ VA+ PI
Sbjct: 421 DYWIVKNSWGTSWGEDGYFRIRRGTDECAIESIAVAATPI 460
>sp|P97821|CATC_MOUSE Dipeptidyl-peptidase I precursor (DPP-I) (DPPI) (Cathepsin C)
           (Cathepsin J) (Dipeptidyl transferase) [Contains:
           Dipeptidyl-peptidase I exclusion domain chain;
           Dipeptidyl-peptidase I heavy chain; Dipeptidyl-peptidase
           I light chain]
          Length = 462

 Score =  310 bits (795), Expect = 3e-84
 Identities = 143/250 (57%), Positives = 189/250 (75%), Gaps = 1/250 (0%)
 Frame = +3

Query: 6   EFHEKTLYEVINMAGGSRSKLERPKPAPITKSILDSVKLIPKSFDWRNVNGVNYVSPVRN 185
           E+ + +L ++I  +G S+ ++ RPKPAP+T  I   +  +P+S+DWRNV GVNYVSPVRN
Sbjct: 192 EYEKMSLRDLIRRSGHSQ-RIPRPKPAPMTDEIQQQILNLPESWDWRNVQGVNYVSPVRN 250

Query: 186 QGGCGSCYSFASAGMLEARYRIRSNNTVRPILSPQDVVECSPYSQGCDGGFPYLIAGKFA 365
           Q  CGSCYSFAS GMLEAR RI +NN+  PILSPQ+VV CSPY+QGCDGGFPYLIAGK+A
Sbjct: 251 QESCGSCYSFASMGMLEARIRILTNNSQTPILSPQEVVSCSPYAQGCDGGFPYLIAGKYA 310

Query: 366 EDFGMAQESCNPYKGMNGKCSTTKDCKRYFATNYKYIGGYYGATNEPLMRMELVRNGPIA 545
           +DFG+ +ESC PY   +  C   ++C RY++++Y Y+GG+YG  NE LM++ELV++GP+A
Sbjct: 311 QDFGVVEESCFPYTAKDSPCKpreNCLRYYSSDYYYVGGFYGGCNEALMKLELVKHGPMA 370

Query: 546 VGFEVYDDFMSYSGGVYHHNFGTRKLTTSKFGFNPFELTNHAVLVVGYG-ETSSGEKFWI 722
           V FEV+DDF+ Y  G+YHH       T     FNPFELTNHAVL+VGYG +  +G ++WI
Sbjct: 371 VAFEVHDDFLHYHSGIYHH-------TGLSDPFNPFELTNHAVLLVGYGRDPVTGIEYWI 423

Query: 723 VKNSWGNGMG 752
           +KNSWG+  G
Sbjct: 424 IKNSWGSNWG 433

 Score = 51.2 bits (121), Expect = 4e-06
 Identities = 22/39 (56%), Positives = 29/39 (74%)
 Frame = +1

Query: 715 FGLLKTVGVTGWGENGYFRIRRGNDECGIESLDVASEPI 831
           + ++K    + WGE+GYFRIRRG DEC IES+ VA+ PI
Sbjct: 421 YWIIKNSWGSNWGESGYFRIRRGTDECAIESIAVAAIPI 459
>sp|O97578|CATC_CANFA Dipeptidyl-peptidase I precursor (DPP-I) (DPPI) (Cathepsin C)
           (Cathepsin J) (Dipeptidyl transferase) [Contains:
           Dipeptidyl-peptidase I exclusion domain chain;
           Dipeptidyl-peptidase I heavy chain 1;
           Dipeptidyl-peptidase I heavy chain 2;
           Dipeptidyl-peptidase I heavy chain 3;
           Dipeptidyl-peptidase I heavy chain 4;
           Dipeptidyl-peptidase I light chain]
          Length = 435

 Score =  304 bits (778), Expect = 3e-82
 Identities = 142/250 (56%), Positives = 183/250 (73%), Gaps = 1/250 (0%)
 Frame = +3

Query: 6   EFHEKTLYEVINMAGGSRSKLERPKPAPITKSILDSVKLIPKSFDWRNVNGVNYVSPVRN 185
           E+   TL +++   GG   K+ RPKP P+T  I + +  +P S+DWRNV G N+VSPVRN
Sbjct: 167 EYETLTLRDMMTRVGGR--KIPRPKPTPLTAEIHEEISRLPTSWDWRNVRGTNFVSPVRN 224

Query: 186 QGGCGSCYSFASAGMLEARYRIRSNNTVRPILSPQDVVECSPYSQGCDGGFPYLIAGKFA 365
           Q  CGSCY+FAS  MLEAR RI +NNT  PILSPQ++V CS Y+QGC+GGFPYLIAGK+A
Sbjct: 225 QASCGSCYAFASTAMLEARIRILTNNTQTPILSPQEIVSCSQYAQGCEGGFPYLIAGKYA 284

Query: 366 EDFGMAQESCNPYKGMNGKCSTTKDCKRYFATNYKYIGGYYGATNEPLMRMELVRNGPIA 545
           +DFG+ +E+C PY G +  C    DC RY+++ Y Y+GG+YGA NE LM++ELVR+GP+A
Sbjct: 285 QDFGLVEEACFPYAGSDSPCK-PNDCFRYYSSEYYYVGGFYGACNEALMKLELVRHGPMA 343

Query: 546 VGFEVYDDFMSYSGGVYHHNFGTRKLTTSKFGFNPFELTNHAVLVVGYG-ETSSGEKFWI 722
           V FEVYDDF  Y  G+Y+H       T  +  FNPFELTNHAVL+VGYG +++SG  +WI
Sbjct: 344 VAFEVYDDFFHYQKGIYYH-------TGLRDPFNPFELTNHAVLLVGYGTDSASGMDYWI 396

Query: 723 VKNSWGNGMG 752
           VKNSWG+  G
Sbjct: 397 VKNSWGSRWG 406

 Score = 51.2 bits (121), Expect = 4e-06
 Identities = 22/40 (55%), Positives = 30/40 (75%)
 Frame = +1

Query: 712 NFGLLKTVGVTGWGENGYFRIRRGNDECGIESLDVASEPI 831
           ++ ++K    + WGE+GYFRIRRG DEC IES+ VA+ PI
Sbjct: 393 DYWIVKNSWGSRWGEDGYFRIRRGTDECAIESIAVAATPI 432
>sp|P80067|CATC_RAT Dipeptidyl-peptidase I precursor (DPP-I) (DPPI) (Cathepsin C)
           (Cathepsin J) (Dipeptidyl transferase) [Contains:
           Dipeptidyl-peptidase I exclusion domain chain;
           Dipeptidyl-peptidase I heavy chain; Dipeptidyl-peptidase
           I light chain]
          Length = 462

 Score =  303 bits (776), Expect = 4e-82
 Identities = 140/248 (56%), Positives = 180/248 (72%), Gaps = 1/248 (0%)
 Frame = +3

Query: 12  HEKTLYEVINMAGGSRSKLERPKPAPITKSILDSVKLIPKSFDWRNVNGVNYVSPVRNQG 191
           +EK     +    G   ++ RPKPAPIT  I   +  +P+S+DWRNV G+N+VSPVRNQ 
Sbjct: 193 YEKLSIRDLIRRSGHSGRILRPKPAPITDEIQQQILSLPESWDWRNVRGINFVSPVRNQE 252

Query: 192 GCGSCYSFASAGMLEARYRIRSNNTVRPILSPQDVVECSPYSQGCDGGFPYLIAGKFAED 371
            CGSCYSFAS GMLEAR RI +NN+  PILSPQ+VV CSPY+QGCDGGFPYLIAGK+A+D
Sbjct: 253 SCGSCYSFASIGMLEARIRILTNNSQTPILSPQEVVSCSPYAQGCDGGFPYLIAGKYAQD 312

Query: 372 FGMAQESCNPYKGMNGKCSTTKDCKRYFATNYKYIGGYYGATNEPLMRMELVRNGPIAVG 551
           FG+ +E+C PY   +  C   ++C RY+++ Y Y+GG+YG  NE LM++ELV++GP+AV 
Sbjct: 313 FGVVEENCFPYTATDAPCKPKENCLRYYSSEYYYVGGFYGGCNEALMKLELVKHGPMAVA 372

Query: 552 FEVYDDFMSYSGGVYHHNFGTRKLTTSKFGFNPFELTNHAVLVVGYG-ETSSGEKFWIVK 728
           FEV+DDF+ Y  G+YHH       T     FNPFELTNHAVL+VGYG +  +G  +WIVK
Sbjct: 373 FEVHDDFLHYHSGIYHH-------TGLSDPFNPFELTNHAVLLVGYGKDPVTGLDYWIVK 425

Query: 729 NSWGNGMG 752
           NSWG+  G
Sbjct: 426 NSWGSQWG 433

 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 21/40 (52%), Positives = 30/40 (75%)
 Frame = +1

Query: 712 NFGLLKTVGVTGWGENGYFRIRRGNDECGIESLDVASEPI 831
           ++ ++K    + WGE+GYFRIRRG DEC IES+ +A+ PI
Sbjct: 420 DYWIVKNSWGSQWGESGYFRIRRGTDECAIESIAMAAIPI 459
>sp|Q26563|CATC_SCHMA Cathepsin C precursor
          Length = 454

 Score =  273 bits (698), Expect = 5e-73
 Identities = 138/264 (52%), Positives = 181/264 (68%), Gaps = 8/264 (3%)
 Frame = +3

Query: 3   PEFHEKTLYEVINMAGGSRSKLERP----KPAPITKSILDSVKLIPKSFDWRNV--NGVN 164
           PE  + T+ E+ N AGG +S + RP    +  P +K ++     +P  FDW +      +
Sbjct: 175 PELSKYTIDELRNRAGGVKSMVTRPSVLNRKTP-SKELISLTGNLPLEFDWTSPPDGSRS 233

Query: 165 YVSPVRNQGGCGSCYSFASAGMLEARYRIRSNNTVRPILSPQDVVECSPYSQGCDGGFPY 344
            V+P+RNQG CGSCY+  SA  LEAR R+ SN + +PILSPQ VV+CSPYS+GC+GGFP+
Sbjct: 234 PVTPIRNQGICGSCYASPSAAALEARIRLVSNFSEQPILSPQTVVDCSPYSEGCNGGFPF 293

Query: 345 LIAGKFAEDFGMAQESCNPYKGMN-GKCSTTKDCKRYFATNYKYIGGYYGATNEPLMRME 521
           LIAGK+ EDFG+ Q+   PY G + GKC+ +K+C RY+ T+Y YIGGYYGATNE LM++E
Sbjct: 294 LIAGKYGEDFGLPQKIVIPYTGEDTGKCTVSKNCTRYYTTDYSYIGGYYGATNEKLMQLE 353

Query: 522 LVRNGPIAVGFEVYDDFMSYSGGVYHHNFGTRKLTTSKFGFNPFELTNHAVLVVGYG-ET 698
           L+ NGP  VGFEVY+DF  Y  G+YHH      + T  + FNPFELTNHAVL+VGYG + 
Sbjct: 354 LISNGPFPVGFEVYEDFQFYKEGIYHHT----TVQTDHYNFNPFELTNHAVLLVGYGVDK 409

Query: 699 SSGEKFWIVKNSWGNGMG*KRIFQ 770
            SGE +W VKNSWG   G +  F+
Sbjct: 410 LSGEPYWKVKNSWGVEWGEQGYFR 433

 Score = 49.7 bits (117), Expect = 1e-05
 Identities = 20/29 (68%), Positives = 23/29 (79%)
 Frame = +1

Query: 748 WGENGYFRIRRGNDECGIESLDVASEPIL 834
           WGE GYFRI RG DECG+ESL V  +P+L
Sbjct: 426 WGEQGYFRILRGTDECGVESLGVRFDPVL 454
>sp|P80884|ANAN_ANACO Ananain precursor
          Length = 345

 Score =  132 bits (333), Expect = 1e-30
 Identities = 77/213 (36%), Positives = 108/213 (50%)
 Frame = +3

Query: 114 VKLIPKSFDWRNVNGVNYVSPVRNQGGCGSCYSFASAGMLEARYRIRSNNTVRPILSPQD 293
           +  +P+S DWR+   V   + V+NQG CGSC++FAS   +E+ Y+I+  N V   LS Q 
Sbjct: 120 ISSVPQSIDWRDSGAV---TSVKNQGRCGSCWAFASIATVESIYKIKRGNLVS--LSEQQ 174

Query: 294 VVECSPYSQGCDGGFPYLIAGKFAEDFGMAQESCNPYKGMNGKCSTTKDCKRYFATNYKY 473
           V++C+  S GC GG+          + G+A  +  PYK   G C T       + T Y Y
Sbjct: 175 VLDCA-VSYGCKGGWINKAYSFIISNKGVASAAIYPYKAAKGTCKTNGVPNSAYITRYTY 233

Query: 474 IGGYYGATNEPLMRMELVRNGPIAVGFEVYDDFMSYSGGVYHHNFGTRKLTTSKFGFNPF 653
           +       N     M  V N PIA   +   +F  Y  GV+    GTR            
Sbjct: 234 V-----QRNNERNMMYAVSNQPIAAALDASGNFQHYKRGVFTGPCGTR------------ 276

Query: 654 ELTNHAVLVVGYGETSSGEKFWIVKNSWGNGMG 752
              NHA++++GYG+ SSG+KFWIV+NSWG G G
Sbjct: 277 --LNHAIVIIGYGQDSSGKKFWIVRNSWGAGWG 307
>sp|Q90686|CATK_CHICK Cathepsin K precursor (JTAP-1)
          Length = 334

 Score =  123 bits (309), Expect = 6e-28
 Identities = 86/249 (34%), Positives = 118/249 (47%), Gaps = 1/249 (0%)
 Frame = +3

Query: 15  EKTLYEVINMAGGSRSKLERPKPAPITKSILDSVKLIPKSFDWRNVNGVNYVSPVRNQGG 194
           + T  EV+    G R    RP+P   T  + D     P + DWR      YV+PV++QG 
Sbjct: 85  DMTSEEVVRTMTGLRVPRSRPRPNG-TLYVPDWSSRAPAAVDWRRKG---YVTPVKDQGQ 140

Query: 195 CGSCYSFASAGMLEARYRIRSNNTVRPILSPQDVVECSPYSQGCDGGFPYLIAGKFAEDF 374
           CGSC++F+S G LE + + R+   +   LSPQ++V C   + GC GG+          + 
Sbjct: 141 CGSCWAFSSVGALEGQLKRRTGKLLS--LSPQNLVYCVSNNNGCGGGYMTNAFEYVRLNR 198

Query: 375 GMAQESCNPYKGMNGKCSTTKDCKRYFATNYKYIGGYYGATNEPLMRMELVRNGPIAVGF 554
           G+  E   PY G +  C  +   K      Y+ I       NE  ++  + R GP++VG 
Sbjct: 199 GIDSEDAYPYIGQDESCMYSPTGKAAKCRGYREI----PEDNEKALKRAVARIGPVSVGI 254

Query: 555 EV-YDDFMSYSGGVYHHNFGTRKLTTSKFGFNPFELTNHAVLVVGYGETSSGEKFWIVKN 731
           +     F  YS GVY+             G NP E  NHAVL VGYG    G K WI+KN
Sbjct: 255 DASLPSFQFYSRGVYYDT-----------GCNP-ENINHAVLAVGYG-AQKGTKHWIIKN 301

Query: 732 SWGNGMG*K 758
           SWG   G K
Sbjct: 302 SWGTEWGNK 310
>sp|O35186|CATK_RAT Cathepsin K precursor
          Length = 329

 Score =  123 bits (308), Expect = 8e-28
 Identities = 75/213 (35%), Positives = 107/213 (50%), Gaps = 1/213 (0%)
 Frame = +3

Query: 123 IPKSFDWRNVNGVNYVSPVRNQGGCGSCYSFASAGMLEARYRIRSNNTVRPILSPQDVVE 302
           +P S D+R      YV+PV+NQG CGSC++F+SAG LE + + ++   +   LSPQ++V+
Sbjct: 115 VPDSIDYRKKG---YVTPVKNQGQCGSCWAFSSAGALEGQLKKKTGKLL--ALSPQNLVD 169

Query: 303 CSPYSQGCDGGFPYLIAGKFAEDFGMAQESCNPYKGMNGKCSTTKDCKRYFATNYKYIGG 482
           C   + GC GG+         ++ G+  E   PY G +  C      K      Y+ I  
Sbjct: 170 CVSENYGCGGGYMTTAFQYVQQNGGIDSEDAYPYVGQDESCMYNATAKAAKCRGYREI-- 227

Query: 483 YYGATNEPLMRMELVRNGPIAVGFEV-YDDFMSYSGGVYHHNFGTRKLTTSKFGFNPFEL 659
                NE  ++  + R GP++V  +     F  YS GVY+     R            + 
Sbjct: 228 --PVGNEKALKRAVARVGPVSVSIDASLTSFQFYSRGVYYDENCDR------------DN 273

Query: 660 TNHAVLVVGYGETSSGEKFWIVKNSWGNGMG*K 758
            NHAVLVVGYG T  G K+WI+KNSWG   G K
Sbjct: 274 VNHAVLVVGYG-TQKGNKYWIIKNSWGESWGNK 305
>sp|P00786|CATH_RAT Cathepsin H precursor (Cathepsin B3) (Cathepsin BA) [Contains:
           Cathepsin H mini chain; Cathepsin H heavy chain;
           Cathepsin H light chain]
          Length = 333

 Score =  122 bits (306), Expect = 1e-27
 Identities = 84/229 (36%), Positives = 110/229 (48%), Gaps = 3/229 (1%)
 Frame = +3

Query: 75  PKPAPITKS-ILDSVKLIPKSFDWRNVNGVNYVSPVRNQGGCGSCYSFASAGMLEARYRI 251
           P+    TKS  L      P S DWR     N VSPV+NQG CGSC++F++ G LE+   I
Sbjct: 97  PQNCSATKSNYLRGTGPYPSSMDWRKKG--NVVSPVKNQGACGSCWTFSTTGALESAVAI 154

Query: 252 RSNNTVRPILSPQDVVECSP--YSQGCDGGFPYLIAGKFAEDFGMAQESCNPYKGMNGKC 425
            S   +   L+ Q +V+C+    + GC GG P         + G+  E   PY G NG+C
Sbjct: 155 ASGKMM--TLAEQQLVDCAQNFNNHGCQGGLPSQAFEYILYNKGIMGEDSYPYIGKNGQC 212

Query: 426 STTKDCKRYFATNYKYIGGYYGATNEPLMRMELVRNGPIAVGFEVYDDFMSYSGGVYHHN 605
               +    F  N   I       +E  M   +    P++  FEV +DFM Y  GVY  N
Sbjct: 213 KFNPEKAVAFVKNVVNI----TLNDEAAMVEAVALYNPVSFAFEVTEDFMMYKSGVYSSN 268

Query: 606 FGTRKLTTSKFGFNPFELTNHAVLVVGYGETSSGEKFWIVKNSWGNGMG 752
             +   T  K         NHAVL VGYGE  +G  +WIVKNSWG+  G
Sbjct: 269 --SCHKTPDK--------VNHAVLAVGYGE-QNGLLYWIVKNSWGSNWG 306

 Score = 34.3 bits (77), Expect = 0.48
 Identities = 16/39 (41%), Positives = 23/39 (58%)
 Frame = +1

Query: 715 FGLLKTVGVTGWGENGYFRIRRGNDECGIESLDVASEPI 831
           + ++K    + WG NGYF I RG + CG+ +   AS PI
Sbjct: 294 YWIVKNSWGSNWGNNGYFLIERGKNMCGLAA--CASYPI 330
  Database: Non-redundant SwissProt sequences
    Posted date:  Dec 6, 2005  7:40 AM
  Number of letters in database: 68,354,980
  Number of sequences in database:  184,735
  
  Database: swissprot.01
    Posted date:  Dec 6, 2005  8:18 AM
  Number of letters in database: 66,202,850
  Number of sequences in database:  184,431
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 111,844,477
Number of Sequences: 369166
Number of extensions: 2506493
Number of successful extensions: 7153
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 6144
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 6613
length of database: 68,354,980
effective HSP length: 110
effective length of database: 48,034,130
effective search space used: 9030416440
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)