Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_024_B07
(342 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P53634|CATC_HUMAN Dipeptidyl-peptidase I precursor (DPP-... 128 5e-30
sp|Q60HG6|CATC_MACFA Dipeptidyl-peptidase I precursor (DPP-... 124 5e-29
sp|Q26563|CATC_SCHMA Cathepsin C precursor 122 2e-28
sp|O97578|CATC_CANFA Dipeptidyl-peptidase I precursor (DPP-... 120 1e-27
sp|P97821|CATC_MOUSE Dipeptidyl-peptidase I precursor (DPP-... 118 5e-27
sp|P80067|CATC_RAT Dipeptidyl-peptidase I precursor (DPP-I)... 115 2e-26
sp|P92131|CATB1_GIALA Cathepsin B-like CP1 precursor (Cathe... 87 2e-17
sp|P25807|CPR1_CAEEL Gut-specific cysteine proteinase precu... 85 6e-17
sp|P92133|CATB3_GIALA Cathepsin B-like CP3 precursor (Cathe... 84 1e-16
sp|P43508|CPR4_CAEEL Cathepsin B-like cysteine proteinase 4... 82 4e-16
>sp|P53634|CATC_HUMAN Dipeptidyl-peptidase I precursor (DPP-I) (DPPI) (Cathepsin C)
(Cathepsin J) (Dipeptidyl transferase) [Contains:
Dipeptidyl-peptidase I exclusion domain chain;
Dipeptidyl-peptidase I heavy chain; Dipeptidyl-peptidase
I light chain]
Length = 463
Score = 128 bits (321), Expect = 5e-30
Identities = 60/92 (65%), Positives = 70/92 (76%), Gaps = 1/92 (1%)
Frame = +1
Query: 1 VYDDFMSYSGGVYHHNFGTRKLTTSKFGFNPFELTNHAVLVVGYG-ETSSGEKFWIVKNS 177
VYDDF+ Y G+YHH T + FNPFELTNHAVL+VGYG +++SG +WIVKNS
Sbjct: 376 VYDDFLHYKKGIYHH-------TGLRDPFNPFELTNHAVLLVGYGTDSASGMDYWIVKNS 428
Query: 178 WGNGWGENGYFRIRRGNDECGIESLGVASEPI 273
WG GWGENGYFRIRRG DEC IES+ VA+ PI
Sbjct: 429 WGTGWGENGYFRIRRGTDECAIESIAVAATPI 460
>sp|Q60HG6|CATC_MACFA Dipeptidyl-peptidase I precursor (DPP-I) (DPPI) (Cathepsin C)
(Cathepsin J) (Dipeptidyl transferase) [Contains:
Dipeptidyl-peptidase I exclusion domain chain;
Dipeptidyl-peptidase I heavy chain; Dipeptidyl-peptidase
I light chain]
Length = 463
Score = 124 bits (312), Expect = 5e-29
Identities = 58/92 (63%), Positives = 69/92 (75%), Gaps = 1/92 (1%)
Frame = +1
Query: 1 VYDDFMSYSGGVYHHNFGTRKLTTSKFGFNPFELTNHAVLVVGYG-ETSSGEKFWIVKNS 177
VYDDF+ Y G+YHH T + FNPFELTNHAVL+VGYG +++SG +WIVKNS
Sbjct: 376 VYDDFLHYQNGIYHH-------TGLRDPFNPFELTNHAVLLVGYGTDSASGMDYWIVKNS 428
Query: 178 WGNGWGENGYFRIRRGNDECGIESLGVASEPI 273
WG WGE+GYFRIRRG DEC IES+ VA+ PI
Sbjct: 429 WGTSWGEDGYFRIRRGTDECAIESIAVAATPI 460
>sp|Q26563|CATC_SCHMA Cathepsin C precursor
Length = 454
Score = 122 bits (307), Expect = 2e-28
Identities = 57/93 (61%), Positives = 67/93 (72%), Gaps = 1/93 (1%)
Frame = +1
Query: 1 VYDDFMSYSGGVYHHNFGTRKLTTSKFGFNPFELTNHAVLVVGYG-ETSSGEKFWIVKNS 177
VY+DF Y G+YHH + T + FNPFELTNHAVL+VGYG + SGE +W VKNS
Sbjct: 366 VYEDFQFYKEGIYHHT----TVQTDHYNFNPFELTNHAVLLVGYGVDKLSGEPYWKVKNS 421
Query: 178 WGNGWGENGYFRIRRGNDECGIESLGVASEPIL 276
WG WGE GYFRI RG DECG+ESLGV +P+L
Sbjct: 422 WGVEWGEQGYFRILRGTDECGVESLGVRFDPVL 454
>sp|O97578|CATC_CANFA Dipeptidyl-peptidase I precursor (DPP-I) (DPPI) (Cathepsin C)
(Cathepsin J) (Dipeptidyl transferase) [Contains:
Dipeptidyl-peptidase I exclusion domain chain;
Dipeptidyl-peptidase I heavy chain 1;
Dipeptidyl-peptidase I heavy chain 2;
Dipeptidyl-peptidase I heavy chain 3;
Dipeptidyl-peptidase I heavy chain 4;
Dipeptidyl-peptidase I light chain]
Length = 435
Score = 120 bits (301), Expect = 1e-27
Identities = 57/92 (61%), Positives = 69/92 (75%), Gaps = 1/92 (1%)
Frame = +1
Query: 1 VYDDFMSYSGGVYHHNFGTRKLTTSKFGFNPFELTNHAVLVVGYG-ETSSGEKFWIVKNS 177
VYDDF Y G+Y+H T + FNPFELTNHAVL+VGYG +++SG +WIVKNS
Sbjct: 348 VYDDFFHYQKGIYYH-------TGLRDPFNPFELTNHAVLLVGYGTDSASGMDYWIVKNS 400
Query: 178 WGNGWGENGYFRIRRGNDECGIESLGVASEPI 273
WG+ WGE+GYFRIRRG DEC IES+ VA+ PI
Sbjct: 401 WGSRWGEDGYFRIRRGTDECAIESIAVAATPI 432
>sp|P97821|CATC_MOUSE Dipeptidyl-peptidase I precursor (DPP-I) (DPPI) (Cathepsin C)
(Cathepsin J) (Dipeptidyl transferase) [Contains:
Dipeptidyl-peptidase I exclusion domain chain;
Dipeptidyl-peptidase I heavy chain; Dipeptidyl-peptidase
I light chain]
Length = 462
Score = 118 bits (295), Expect = 5e-27
Identities = 55/92 (59%), Positives = 68/92 (73%), Gaps = 1/92 (1%)
Frame = +1
Query: 1 VYDDFMSYSGGVYHHNFGTRKLTTSKFGFNPFELTNHAVLVVGYG-ETSSGEKFWIVKNS 177
V+DDF+ Y G+YHH T FNPFELTNHAVL+VGYG + +G ++WI+KNS
Sbjct: 375 VHDDFLHYHSGIYHH-------TGLSDPFNPFELTNHAVLLVGYGRDPVTGIEYWIIKNS 427
Query: 178 WGNGWGENGYFRIRRGNDECGIESLGVASEPI 273
WG+ WGE+GYFRIRRG DEC IES+ VA+ PI
Sbjct: 428 WGSNWGESGYFRIRRGTDECAIESIAVAAIPI 459
>sp|P80067|CATC_RAT Dipeptidyl-peptidase I precursor (DPP-I) (DPPI) (Cathepsin C)
(Cathepsin J) (Dipeptidyl transferase) [Contains:
Dipeptidyl-peptidase I exclusion domain chain;
Dipeptidyl-peptidase I heavy chain; Dipeptidyl-peptidase
I light chain]
Length = 462
Score = 115 bits (289), Expect = 2e-26
Identities = 55/92 (59%), Positives = 67/92 (72%), Gaps = 1/92 (1%)
Frame = +1
Query: 1 VYDDFMSYSGGVYHHNFGTRKLTTSKFGFNPFELTNHAVLVVGYGETS-SGEKFWIVKNS 177
V+DDF+ Y G+YHH T FNPFELTNHAVL+VGYG+ +G +WIVKNS
Sbjct: 375 VHDDFLHYHSGIYHH-------TGLSDPFNPFELTNHAVLLVGYGKDPVTGLDYWIVKNS 427
Query: 178 WGNGWGENGYFRIRRGNDECGIESLGVASEPI 273
WG+ WGE+GYFRIRRG DEC IES+ +A+ PI
Sbjct: 428 WGSQWGESGYFRIRRGTDECAIESIAMAAIPI 459
>sp|P92131|CATB1_GIALA Cathepsin B-like CP1 precursor (Cathepsin B-like protease B1)
Length = 303
Score = 86.7 bits (213), Expect = 2e-17
Identities = 43/82 (52%), Positives = 49/82 (59%)
Frame = +1
Query: 1 VYDDFMSYSGGVYHHNFGTRKLTTSKFGFNPFELTNHAVLVVGYGETSSGEKFWIVKNSW 180
VY D Y GVY H +GT L GF HA+ +VGYG T G +WI+KNSW
Sbjct: 225 VYADLSYYESGVYKHTYGTINL-----GF-------HALEIVGYGTTDDGTDYWIIKNSW 272
Query: 181 GNGWGENGYFRIRRGNDECGIE 246
G WGENGYFRI RG +EC IE
Sbjct: 273 GPDWGENGYFRIVRGVNECRIE 294
>sp|P25807|CPR1_CAEEL Gut-specific cysteine proteinase precursor
Length = 329
Score = 84.7 bits (208), Expect = 6e-17
Identities = 41/89 (46%), Positives = 55/89 (61%)
Frame = +1
Query: 1 VYDDFMSYSGGVYHHNFGTRKLTTSKFGFNPFELTNHAVLVVGYGETSSGEKFWIVKNSW 180
VY+DF Y GVY H T K+ L HA+ ++G+G T SG +W+V NSW
Sbjct: 252 VYEDFYKYKSGVYKH-------TAGKY------LGGHAIKIIGWG-TESGSPYWLVANSW 297
Query: 181 GNGWGENGYFRIRRGNDECGIESLGVASE 267
G WGE+G+F+I RG+D+CGIES VA +
Sbjct: 298 GVNWGESGFFKIYRGDDQCGIESAVVAGK 326
>sp|P92133|CATB3_GIALA Cathepsin B-like CP3 precursor (Cathepsin B-like protease B3)
Length = 299
Score = 83.6 bits (205), Expect = 1e-16
Identities = 40/82 (48%), Positives = 47/82 (57%)
Frame = +1
Query: 1 VYDDFMSYSGGVYHHNFGTRKLTTSKFGFNPFELTNHAVLVVGYGETSSGEKFWIVKNSW 180
VY DFM Y GVY H +G + HAV +VGYG G +WI+KNSW
Sbjct: 221 VYSDFMYYESGVYQHTYGRVE-------------GGHAVDMVGYGTDDDGVDYWIIKNSW 267
Query: 181 GNGWGENGYFRIRRGNDECGIE 246
G WGE+GYFRI R +ECGIE
Sbjct: 268 GPDWGEDGYFRIIRMTNECGIE 289
>sp|P43508|CPR4_CAEEL Cathepsin B-like cysteine proteinase 4 precursor (Cysteine
protease-related 4)
Length = 335
Score = 82.0 bits (201), Expect = 4e-16
Identities = 41/90 (45%), Positives = 50/90 (55%)
Frame = +1
Query: 1 VYDDFMSYSGGVYHHNFGTRKLTTSKFGFNPFELTNHAVLVVGYGETSSGEKFWIVKNSW 180
VY+DF Y GVY H G EL HA+ ++G+G T +G +W+V NSW
Sbjct: 258 VYEDFYQYKTGVYVHTTGQ-------------ELGGHAIRILGWG-TDNGTPYWLVANSW 303
Query: 181 GNGWGENGYFRIRRGNDECGIESLGVASEP 270
WGENGYFRI RG +ECGIE V P
Sbjct: 304 NVNWGENGYFRIIRGTNECGIEHAVVGGVP 333
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 40,656,196
Number of Sequences: 369166
Number of extensions: 841024
Number of successful extensions: 2610
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 2409
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 2459
length of database: 68,354,980
effective HSP length: 81
effective length of database: 53,391,445
effective search space used: 1708526240
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)