Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_009_N21
(810 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P97821|CATC_MOUSE Dipeptidyl-peptidase I precursor (DPP-... 178 2e-44
sp|P53634|CATC_HUMAN Dipeptidyl-peptidase I precursor (DPP-... 176 7e-44
sp|Q60HG6|CATC_MACFA Dipeptidyl-peptidase I precursor (DPP-... 172 1e-42
sp|P80067|CATC_RAT Dipeptidyl-peptidase I precursor (DPP-I)... 170 4e-42
sp|O97578|CATC_CANFA Dipeptidyl-peptidase I precursor (DPP-... 165 1e-40
sp|Q26563|CATC_SCHMA Cathepsin C precursor 143 5e-34
sp|Q9WUU7|CATZ_MOUSE Cathepsin Z precursor 41 0.003
sp|Q9R1T3|CATZ_RAT Cathepsin Z precursor (Cathepsin Y) 41 0.003
sp|Q9UBR2|CATZ_HUMAN Cathepsin Z precursor (Cathepsin X) (C... 40 0.008
sp|P43296|RD19A_ARATH Cysteine proteinase RD19a precursor (... 35 0.32
>sp|P97821|CATC_MOUSE Dipeptidyl-peptidase I precursor (DPP-I) (DPPI) (Cathepsin C)
(Cathepsin J) (Dipeptidyl transferase) [Contains:
Dipeptidyl-peptidase I exclusion domain chain;
Dipeptidyl-peptidase I heavy chain; Dipeptidyl-peptidase
I light chain]
Length = 462
Score = 178 bits (451), Expect = 2e-44
Identities = 101/253 (39%), Positives = 140/253 (55%), Gaps = 12/253 (4%)
Frame = +3
Query: 87 MMLAILLAFCLVQLSVSDTPANCTYQDVIGKWQVFTG----NFNVSCSTSKLVATKTLTL 254
++L +LL C V+ SDTPANCTY D++G W G +++CS + K +
Sbjct: 11 VLLLVLLGVCTVR---SDTPANCTYPDLLGTWVFQVGPRSSRSDINCSVMEATEEKVVVH 67
Query: 255 IYP-NWAVDEFGNYGKWTLIYNQGFEVTITNKKYFGFFDYKKINSTYTISYCDRLQPNWF 431
+ + A DE GN G +TLIYNQGFE+ + + K+F FF Y+ T ISYC W
Sbjct: 68 LKKLDTAYDELGNSGHFTLIYNQGFEIVLNDYKWFAFFKYEVRGHT-AISYCHETMTGWV 126
Query: 432 HDVLIRQWQCFKAQRITTLKEKNNVLPHSNIFALTSLR-------YGSQKRIVDKINLEN 590
HDVL R W CF +++ + EK N+ N L L+ Y V IN
Sbjct: 127 HDVLGRNWACFVGKKVESHIEKVNM----NAAHLGGLQERYSERLYTHNHNFVKAINTVQ 182
Query: 591 NGWTAKDYPEFHEKTLYEVINMAGGSRSKLERPKPAPITKSILDSVKLIPKSFDWRNVNG 770
WTA Y E+ + +L ++I +G S+ ++ RPKPAP+T I + +P+S+DWRNV G
Sbjct: 183 KSWTATAYKEYEKMSLRDLIRRSGHSQ-RIPRPKPAPMTDEIQQQILNLPESWDWRNVQG 241
Query: 771 VNYVSPVRNQGGC 809
VNYVSPVRNQ C
Sbjct: 242 VNYVSPVRNQESC 254
>sp|P53634|CATC_HUMAN Dipeptidyl-peptidase I precursor (DPP-I) (DPPI) (Cathepsin C)
(Cathepsin J) (Dipeptidyl transferase) [Contains:
Dipeptidyl-peptidase I exclusion domain chain;
Dipeptidyl-peptidase I heavy chain; Dipeptidyl-peptidase
I light chain]
Length = 463
Score = 176 bits (446), Expect = 7e-44
Identities = 100/257 (38%), Positives = 138/257 (53%), Gaps = 19/257 (7%)
Frame = +3
Query: 96 AILLAFCLVQLSVS-----DTPANCTYQDVIGKWQVFTGNF----NVSCSTSKLVATKTL 248
++LLA L+ LS DTPANCTY D++G W G+ +V+CS K +
Sbjct: 6 SLLLAALLLLLSGDGAVRCDTPANCTYLDLLGTWVFQVGSSGSQRDVNCSVMGPQEKKVV 65
Query: 249 TLIYP-NWAVDEFGNYGKWTLIYNQGFEVTITNKKYFGFFDYKKINSTYTISYCDRLQPN 425
+ + A D+ GN G +T+IYNQGFE+ + + K+F FF YK+ S T +YC+
Sbjct: 66 VYLQKLDTAYDDLGNSGHFTIIYNQGFEIVLNDYKWFAFFKYKEEGSKVT-TYCNETMTG 124
Query: 426 WFHDVLIRQWQCFKAQRITTLKE---------KNNVLPHSNIFALTSLRYGSQKRIVDKI 578
W HDVL R W CF +++ T E KN+ +SN Y V I
Sbjct: 125 WVHDVLGRNWACFTGKKVGTASENVYVNTAHLKNSQEKYSNRL------YKYDHNFVKAI 178
Query: 579 NLENNGWTAKDYPEFHEKTLYEVINMAGGSRSKLERPKPAPITKSILDSVKLIPKSFDWR 758
N WTA Y E+ TL ++I +GG K+ RPKPAP+T I + +P S+DWR
Sbjct: 179 NAIQKSWTATTYMEYETLTLGDMIRRSGGHSRKIPRPKPAPLTAEIQQKILHLPTSWDWR 238
Query: 759 NVNGVNYVSPVRNQGGC 809
NV+G+N+VSPVRNQ C
Sbjct: 239 NVHGINFVSPVRNQASC 255
>sp|Q60HG6|CATC_MACFA Dipeptidyl-peptidase I precursor (DPP-I) (DPPI) (Cathepsin C)
(Cathepsin J) (Dipeptidyl transferase) [Contains:
Dipeptidyl-peptidase I exclusion domain chain;
Dipeptidyl-peptidase I heavy chain; Dipeptidyl-peptidase
I light chain]
Length = 463
Score = 172 bits (436), Expect = 1e-42
Identities = 100/257 (38%), Positives = 135/257 (52%), Gaps = 19/257 (7%)
Frame = +3
Query: 96 AILLAFCLVQLSVS-----DTPANCTYQDVIGKWQVFTGNF----NVSCSTSKLVATKTL 248
A LLA L+ LS DTPANCTY D++G W G+ +V+CS K +
Sbjct: 6 ASLLAALLLLLSGDRAVRCDTPANCTYLDLLGTWVFQVGSSGSLRDVNCSVMGPPEKKVV 65
Query: 249 TLIYP-NWAVDEFGNYGKWTLIYNQGFEVTITNKKYFGFFDYKKINSTYTISYCDRLQPN 425
+ + A D+ GN G +T+IYNQGFE+ + + K+F FF YK+ TI YC+
Sbjct: 66 VHLQKLDTAYDDLGNSGHFTIIYNQGFEIVLNDYKWFAFFKYKEEGIKVTI-YCNETMTG 124
Query: 426 WFHDVLIRQWQCFKAQRITTLKE---------KNNVLPHSNIFALTSLRYGSQKRIVDKI 578
W HDVL R W CF +++ T E KN+ +SN Y V I
Sbjct: 125 WVHDVLGRNWACFTGKKVGTASENVYVNTAHLKNSQEKYSNRL------YKYDHNFVKAI 178
Query: 579 NLENNGWTAKDYPEFHEKTLYEVINMAGGSRSKLERPKPAPITKSILDSVKLIPKSFDWR 758
N WTA Y E+ TL ++I +GG K+ RPKP P+T I + +P S+DWR
Sbjct: 179 NAIQKSWTATTYMEYETLTLGDMIKRSGGHSRKIPRPKPTPLTAEIQQKILHLPTSWDWR 238
Query: 759 NVNGVNYVSPVRNQGGC 809
NV+G+N+VSPVRNQ C
Sbjct: 239 NVHGINFVSPVRNQASC 255
>sp|P80067|CATC_RAT Dipeptidyl-peptidase I precursor (DPP-I) (DPPI) (Cathepsin C)
(Cathepsin J) (Dipeptidyl transferase) [Contains:
Dipeptidyl-peptidase I exclusion domain chain;
Dipeptidyl-peptidase I heavy chain; Dipeptidyl-peptidase
I light chain]
Length = 462
Score = 170 bits (431), Expect = 4e-42
Identities = 97/252 (38%), Positives = 135/252 (53%), Gaps = 12/252 (4%)
Frame = +3
Query: 90 MLAILLAFCLVQLSVSDTPANCTYQDVIGKWQVFTG----NFNVSCSTSKLVATK-TLTL 254
+L +LL C V SDTPANCTY D++G W G +++CS + K + L
Sbjct: 12 LLLVLLGVCTVS---SDTPANCTYPDLLGTWVFQVGPRHPRSHINCSVMEPTEEKVVIHL 68
Query: 255 IYPNWAVDEFGNYGKWTLIYNQGFEVTITNKKYFGFFDYKKINSTYTISYCDRLQPNWFH 434
+ A DE GN G +TLIYNQGFE+ + + K+F FF Y ++ + ISYC W H
Sbjct: 69 KKLDTAYDEVGNSGYFTLIYNQGFEIVLNDYKWFAFFKY-EVKGSRAISYCHETMTGWVH 127
Query: 435 DVLIRQWQCFKAQRITTLKEKNNVLPHSNIFALTSLR-------YGSQKRIVDKINLENN 593
D L R W CF +++ EK V N+ L L+ Y V IN
Sbjct: 128 DYLGRNWACFVGKKMANHSEKVYV----NVAHLGGLQEKYSERLYSHHHNFVKAINSVQK 183
Query: 594 GWTAKDYPEFHEKTLYEVINMAGGSRSKLERPKPAPITKSILDSVKLIPKSFDWRNVNGV 773
WTA Y + + ++ ++I +G S ++ RPKPAPIT I + +P+S+DWRNV G+
Sbjct: 184 SWTATTYRRYEKLSIRDLIRRSGHS-GRILRPKPAPITDEIQQQILSLPESWDWRNVRGI 242
Query: 774 NYVSPVRNQGGC 809
N+VSPVRNQ C
Sbjct: 243 NFVSPVRNQESC 254
>sp|O97578|CATC_CANFA Dipeptidyl-peptidase I precursor (DPP-I) (DPPI) (Cathepsin C)
(Cathepsin J) (Dipeptidyl transferase) [Contains:
Dipeptidyl-peptidase I exclusion domain chain;
Dipeptidyl-peptidase I heavy chain 1;
Dipeptidyl-peptidase I heavy chain 2;
Dipeptidyl-peptidase I heavy chain 3;
Dipeptidyl-peptidase I heavy chain 4;
Dipeptidyl-peptidase I light chain]
Length = 435
Score = 165 bits (418), Expect = 1e-40
Identities = 94/236 (39%), Positives = 126/236 (53%), Gaps = 12/236 (5%)
Frame = +3
Query: 138 DTPANCTYQDVIGKWQVF----TGNFNVSCSTSKLVATKTLTLIYP-NWAVDEFGNYGKW 302
DTPANCT+ +++G W VF G+ +V+CS K + + + A D FGN G +
Sbjct: 1 DTPANCTHPELLGTW-VFQVGPAGSRSVNCSVMGPPEKKVVVHLEKLDTAYDNFGNTGHF 59
Query: 303 TLIYNQGFEVTITNKKYFGFFDYKKINSTYTISYCDRLQPNWFHDVLIRQWQCFKAQRIT 482
T+IYNQGFE+ + + K+F FF YK+ T SYC+ W HDVL R W CF ++
Sbjct: 60 TIIYNQGFEIVLNDYKWFAFFKYKEEGHKVT-SYCNETMTGWVHDVLGRNWACFTGTKMG 118
Query: 483 TLKEKNNV-------LPHSNIFALTSLRYGSQKRIVDKINLENNGWTAKDYPEFHEKTLY 641
T EK V L +N L Y V IN WTA Y E+ TL
Sbjct: 119 TTSEKAKVNTKHIERLQENNSNRLYKYNY----EFVKAINTIQKSWTATRYIEYETLTLR 174
Query: 642 EVINMAGGSRSKLERPKPAPITKSILDSVKLIPKSFDWRNVNGVNYVSPVRNQGGC 809
+++ GG K+ RPKP P+T I + + +P S+DWRNV G N+VSPVRNQ C
Sbjct: 175 DMMTRVGGR--KIPRPKPTPLTAEIHEEISRLPTSWDWRNVRGTNFVSPVRNQASC 228
>sp|Q26563|CATC_SCHMA Cathepsin C precursor
Length = 454
Score = 143 bits (361), Expect = 5e-34
Identities = 89/245 (36%), Positives = 128/245 (52%), Gaps = 8/245 (3%)
Frame = +3
Query: 99 ILLAFCLVQLSVSDTPANCTYQDVIGKWQVFTGNFNVSCSTSKLVATKT--LTLIYPNWA 272
IL+ ++ + +DTPANCTY+D G+W+ G++ C KL + ++ ++L+YP+ A
Sbjct: 8 ILIILACLRFTCADTPANCTYEDAHGRWKFHIGDYQSKCP-EKLNSKQSVVISLLYPDIA 66
Query: 273 VDEFGNYGKWTLIYNQGFEVTITNKKYFGFFDYKKINSTYTISYCDRLQPNWFHDVLIRQ 452
+DEFGN G WTLIYNQGFEVTI ++K+ F YK N + C + P W HD LI
Sbjct: 67 IDEFGNRGHWTLIYNQGFEVTINHRKWLVIFAYKS-NGEFN---CHKSMPMWTHDTLIDS 122
Query: 453 WQCFKAQRITTLKEKNNVLPHSNIFALTSLRYGSQKRIVDKINLENNGWTAKDYPEFHEK 632
+ K N L S F T Y V KIN W + YPE +
Sbjct: 123 GSVCSGKIGVHDKFHINKLFGSKSFGRT--LYHINPSFVGKINAHQKSWRGEIYPELSKY 180
Query: 633 TLYEVINMAGGSRSKLERP----KPAPITKSILDSVKLIPKSFDWRNV--NGVNYVSPVR 794
T+ E+ N AGG +S + RP + P +K ++ +P FDW + + V+P+R
Sbjct: 181 TIDELRNRAGGVKSMVTRPSVLNRKTP-SKELISLTGNLPLEFDWTSPPDGSRSPVTPIR 239
Query: 795 NQGGC 809
NQG C
Sbjct: 240 NQGIC 244
>sp|Q9WUU7|CATZ_MOUSE Cathepsin Z precursor
Length = 306
Score = 41.2 bits (95), Expect = 0.003
Identities = 16/22 (72%), Positives = 19/22 (86%)
Frame = +3
Query: 735 IPKSFDWRNVNGVNYVSPVRNQ 800
+PK++DWRNVNGVNY S RNQ
Sbjct: 64 LPKNWDWRNVNGVNYASVTRNQ 85
>sp|Q9R1T3|CATZ_RAT Cathepsin Z precursor (Cathepsin Y)
Length = 306
Score = 41.2 bits (95), Expect = 0.003
Identities = 16/22 (72%), Positives = 19/22 (86%)
Frame = +3
Query: 735 IPKSFDWRNVNGVNYVSPVRNQ 800
+PK++DWRNVNGVNY S RNQ
Sbjct: 64 LPKNWDWRNVNGVNYASVTRNQ 85
>sp|Q9UBR2|CATZ_HUMAN Cathepsin Z precursor (Cathepsin X) (Cathepsin P)
Length = 303
Score = 40.0 bits (92), Expect = 0.008
Identities = 16/22 (72%), Positives = 19/22 (86%)
Frame = +3
Query: 735 IPKSFDWRNVNGVNYVSPVRNQ 800
+PKS+DWRNV+GVNY S RNQ
Sbjct: 62 LPKSWDWRNVDGVNYASITRNQ 83
>sp|P43296|RD19A_ARATH Cysteine proteinase RD19a precursor (RD19)
Length = 368
Score = 34.7 bits (78), Expect = 0.32
Identities = 22/64 (34%), Positives = 33/64 (51%)
Frame = +3
Query: 618 EFHEKTLYEVINMAGGSRSKLERPKPAPITKSILDSVKLIPKSFDWRNVNGVNYVSPVRN 797
+F + T E G RS + PK A K+ + + +P+ FDWR+ V+PV+N
Sbjct: 98 QFSDLTRSEFRKKHLGVRSGFKLPKDA--NKAPILPTENLPEDFDWRDHGA---VTPVKN 152
Query: 798 QGGC 809
QG C
Sbjct: 153 QGSC 156
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 92,240,073
Number of Sequences: 369166
Number of extensions: 1857420
Number of successful extensions: 4453
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4293
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4421
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 7715018400
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)