Planaria EST Database

DrC_00420

BLASTX 2.2.13 [Nov-27-2005]

Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= DrC_00420
         (1055 letters)

Database: Non-redundant SwissProt sequences 
           184,735 sequences; 68,354,980 total letters



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

sp|P25782|CYSP2_HOMAM  Digestive cysteine proteinase 2 precu...   323   7e-88
sp|Q9GL24|CATL_CANFA  Cathepsin L precursor [Contains: Cathe...   320   3e-87
sp|P07154|CATL_RAT  Cathepsin L precursor (Major excreted pr...   318   2e-86
sp|P43236|CATK_RABIT  Cathepsin K precursor (OC-2 protein)        317   3e-86
sp|O60911|CATL2_HUMAN  Cathepsin L2 precursor (Cathepsin V) ...   317   3e-86
sp|P07711|CATL_HUMAN  Cathepsin L precursor (Major excreted ...   317   4e-86
sp|O35186|CATK_RAT  Cathepsin K precursor                         316   6e-86
sp|Q28944|CATL_PIG  Cathepsin L precursor [Contains: Catheps...   316   8e-86
sp|Q9GLE3|CATK_PIG  Cathepsin K precursor                         316   8e-86
sp|P61277|CATK_MACMU  Cathepsin K precursor >gi|47117667|sp|...   314   3e-85

>sp|P25782|CYSP2_HOMAM Digestive cysteine proteinase 2 precursor
          Length = 323

 Score =  323 bits (827), Expect = 7e-88
 Identities = 161/304 (52%), Positives = 204/304 (67%), Gaps = 2/304 (0%)
 Frame = +1

Query: 76  WESYKIKFGKKYESLNEIS-RRLIWESNLKYIQKHNIESDLGKHTYTLGLNHFADMTNEE 252
           WE +K K+G++Y    E S RR+I+E N KYI++ N + + G+ T+ L +N F DMT EE
Sbjct: 20  WEHFKGKYGRQYVDAEEDSYRRVIFEQNQKYIEEFNKKYENGEVTFNLAMNKFGDMTLEE 79

Query: 253 FRAKYLSVPPSRKKISTVFMAPKNMGKLPDTVDWRTEGYVTPVKNQEQCGSCWSFSATGS 432
           F A      P R    +VF   K  G     VDWRT+G VTPVK+Q QCGSCW+FS TGS
Sbjct: 80  FNAVMKGNIPRRSAPVSVFYPKKETGPQATEVDWRTKGAVTPVKDQGQCGSCWAFSTTGS 139

Query: 433 LEGQHFRKTGNLTSFSEQQLVDXXXXXXXXXXXXXLMDNAFEYIE-KFGIESEDAYPYTA 609
           LEGQHF KTG+L S +EQQLVD              M++AF+YI+   GI++E AYPY A
Sbjct: 140 LEGQHFLKTGSLISLAEQQLVDCSRPYGPQGCNGGWMNDAFDYIKANNGIDTEAAYPYEA 199

Query: 610 EDGTCLYDKSKVVGSCTGYVDIPGGSETSLATAAATVGPISVAIDASNYSFQLYKSGIYN 789
            DG+C +D + V  +C+G+ +I  GSET L  A   +GPISV IDA++ SFQ Y SG+Y 
Sbjct: 200 RDGSCRFDSNSVAATCSGHTNIASGSETGLQQAVRDIGPISVTIDAAHSSFQFYSSGVYY 259

Query: 790 EPDCSSTQLDHGVLVVGYGTEDGSNYWLVKNSWGTVWGIDGYIKMSKDANNQCGIATMAS 969
           EP CS + LDH VL VGYG+E G ++WLVKNSW T WG  GYIKMS++ NN CGIAT+AS
Sbjct: 260 EPSCSPSYLDHAVLAVGYGSEGGQDFWLVKNSWATSWGDAGYIKMSRNRNNNCGIATVAS 319

Query: 970 YPLV 981
           YPLV
Sbjct: 320 YPLV 323

>sp|Q9GL24|CATL_CANFA Cathepsin L precursor [Contains: Cathepsin L heavy chain; Cathepsin
           L light chain]
          Length = 333

 Score =  320 bits (821), Expect = 3e-87
 Identities = 169/330 (51%), Positives = 207/330 (62%), Gaps = 5/330 (1%)
 Frame = +1

Query: 7   ALVFVVAHVAPHKLTVNSELNDDWESYKIKFGKKYESLNEISRRLIWESNLKYIQKHNIE 186
           AL   +A  AP     +  LN  W  +K    + Y    E  RR +WE N+K I+ HN E
Sbjct: 9   ALCLGIASAAPK---FDQSLNAQWYQWKATHRRLYGMNEEGWRRAVWEKNMKMIELHNRE 65

Query: 187 SDLGKHTYTLGLNHFADMTNEEFRAKYLSVPPSRKKISTVFMAPKNMGKLPDTVDWRTEG 366
              GKH +T+ +N F DMTNEEFR         + K   +F  P    ++P +VDWR +G
Sbjct: 66  YSQGKHGFTMAMNAFGDMTNEEFRQVMNGFQNQKHKKGKMFQEPL-FAEIPKSVDWREKG 124

Query: 367 YVTPVKNQEQCGSCWSFSATGSLEGQHFRKTGNLTSFSEQQLVDXXXXXXXXXXXXXLMD 546
           YVTPVKNQ QCGSCW+FSATG+LEGQ FRKTG L S SEQ LVD             LMD
Sbjct: 125 YVTPVKNQGQCGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSRAQGNEGCNGGLMD 184

Query: 547 NAFEYI-EKFGIESEDAYPYTAED-GTCLYDKSKVVGSCTGYVDIPGGSETSLATAAATV 720
           NAF Y+ +  G++SE++YPY   D  TC Y       + TG+VD+P   E +L  A AT+
Sbjct: 185 NAFRYVKDNGGLDSEESYPYLGRDTETCNYKPECSAANDTGFVDLP-QREKALMKAVATL 243

Query: 721 GPISVAIDASNYSFQLYKSGIYNEPDCSSTQLDHGVLVVGY---GTEDGSNYWLVKNSWG 891
           GPISVAIDA + SFQ YKSGIY +PDCSS  LDHGVLVVGY   GT+  + +W+VKNSWG
Sbjct: 244 GPISVAIDAGHQSFQFYKSGIYFDPDCSSKDLDHGVLVVGYGFEGTDSNNKFWIVKNSWG 303

Query: 892 TVWGIDGYIKMSKDANNQCGIATMASYPLV 981
             WG +GY+KM+KD NN CGIAT ASYP V
Sbjct: 304 PEWGWNGYVKMAKDQNNHCGIATAASYPTV 333

>sp|P07154|CATL_RAT Cathepsin L precursor (Major excreted protein) (MEP) (Cyclic
           protein 2) (CP-2) [Contains: Cathepsin L heavy chain;
           Cathepsin L light chain]
          Length = 334

 Score =  318 bits (815), Expect = 2e-86
 Identities = 167/310 (53%), Positives = 202/310 (65%), Gaps = 5/310 (1%)
 Frame = +1

Query: 67  NDDWESYKIKFGKKYESLNEISRRLIWESNLKYIQKHNIESDLGKHTYTLGLNHFADMTN 246
           N  W  +K    + Y +  E  RR +WE N++ IQ HN E   GKH +T+ +N F DMTN
Sbjct: 26  NAQWHQWKSTHRRLYGTNEEEWRRAVWEKNMRMIQLHNGEYSNGKHGFTMEMNAFGDMTN 85

Query: 247 EEFRAKYLSVPPSRKKISTVFMAPKNMGKLPDTVDWRTEGYVTPVKNQEQCGSCWSFSAT 426
           EEFR         + K   +F  P  M ++P TVDWR +G VTPVKNQ QCGSCW+FSA+
Sbjct: 86  EEFRQIVNGYRHQKHKKGRLFQEPL-MLQIPKTVDWREKGCVTPVKNQGQCGSCWAFSAS 144

Query: 427 GSLEGQHFRKTGNLTSFSEQQLVDXXXXXXXXXXXXXLMDNAFEYI-EKFGIESEDAYPY 603
           G LEGQ F KTG L S SEQ LVD             LMD AF+YI E  G++SE++YPY
Sbjct: 145 GCLEGQMFLKTGKLISLSEQNLVDCSHDQGNQGCNGGLMDFAFQYIKENGGLDSEESYPY 204

Query: 604 TAEDGTCLYDKSKVVGSCTGYVDIPGGSETSLATAAATVGPISVAIDASNYSFQLYKSGI 783
            A+DG+C Y     V + TG+VDIP   E +L  A ATVGPISVA+DAS+ S Q Y SGI
Sbjct: 205 EAKDGSCKYRAEYAVANDTGFVDIP-QQEKALMKAVATVGPISVAMDASHPSLQFYSSGI 263

Query: 784 YNEPDCSSTQLDHGVLVVGYGTE----DGSNYWLVKNSWGTVWGIDGYIKMSKDANNQCG 951
           Y EP+CSS  LDHGVLVVGYG E    +   YWLVKNSWG  WG+DGYIK++KD NN CG
Sbjct: 264 YYEPNCSSKDLDHGVLVVGYGYEGTDSNKDKYWLVKNSWGKEWGMDGYIKIAKDRNNHCG 323

Query: 952 IATMASYPLV 981
           +AT ASYP+V
Sbjct: 324 LATAASYPIV 333

>sp|P43236|CATK_RABIT Cathepsin K precursor (OC-2 protein)
          Length = 329

 Score =  317 bits (813), Expect = 3e-86
 Identities = 155/308 (50%), Positives = 206/308 (66%), Gaps = 4/308 (1%)
 Frame = +1

Query: 64  LNDDWESYKIKFGKKYES-LNEISRRLIWESNLKYIQKHNIESDLGKHTYTLGLNHFADM 240
           L+  WE +K  + K+Y S ++EISRRLIWE NLK+I  HN+E+ LG HTY L +NH  DM
Sbjct: 22  LDTQWELWKKTYSKQYNSKVDEISRRLIWEKNLKHISIHNLEASLGVHTYELAMNHLGDM 81

Query: 241 TNEEFRAKY--LSVPPSRKKISTVFMAPKNMGKLPDTVDWRTEGYVTPVKNQEQCGSCWS 414
           T+EE   K   L VPPSR   +     P   G+ PD++D+R +GYVTPVKNQ QCGSCW+
Sbjct: 82  TSEEVVQKMTGLKVPPSRSHSNDTLYIPDWEGRTPDSIDYRKKGYVTPVKNQGQCGSCWA 141

Query: 415 FSATGSLEGQHFRKTGNLTSFSEQQLVDXXXXXXXXXXXXXLMDNAFEYIEKF-GIESED 591
           FS+ G+LEGQ  +KTG L + S Q LVD              M NAF+Y+++  GI+SED
Sbjct: 142 FSSVGALEGQLKKKTGKLLNLSPQNLVDCVSENYGCGGGY--MTNAFQYVQRNRGIDSED 199

Query: 592 AYPYTAEDGTCLYDKSKVVGSCTGYVDIPGGSETSLATAAATVGPISVAIDASNYSFQLY 771
           AYPY  +D +C+Y+ +     C GY +IP G+E +L  A A VGP+SVAIDAS  SFQ Y
Sbjct: 200 AYPYVGQDESCMYNPTGKAAKCRGYREIPEGNEKALKRAVARVGPVSVAIDASLTSFQFY 259

Query: 772 KSGIYNEPDCSSTQLDHGVLVVGYGTEDGSNYWLVKNSWGTVWGIDGYIKMSKDANNQCG 951
             G+Y + +CSS  ++H VL VGYG + G+ +W++KNSWG  WG  GYI M+++ NN CG
Sbjct: 260 SKGVYYDENCSSDNVNHAVLAVGYGIQKGNKHWIIKNSWGESWGNKGYILMARNKNNACG 319

Query: 952 IATMASYP 975
           IA +AS+P
Sbjct: 320 IANLASFP 327

>sp|O60911|CATL2_HUMAN Cathepsin L2 precursor (Cathepsin V) (Cathepsin U)
          Length = 334

 Score =  317 bits (813), Expect = 3e-86
 Identities = 164/314 (52%), Positives = 200/314 (63%), Gaps = 5/314 (1%)
 Frame = +1

Query: 55  NSELNDDWESYKIKFGKKYESLNEISRRLIWESNLKYIQKHNIESDLGKHTYTLGLNHFA 234
           +  L+  W  +K    + Y +  E  RR +WE N+K I+ HN E   GKH +T+ +N F 
Sbjct: 22  DQNLDTKWYQWKATHRRLYGANEEGWRRAVWEKNMKMIELHNGEYSQGKHGFTMAMNAFG 81

Query: 235 DMTNEEFRAKYLSVPPSRKKISTVFMAPKNMGKLPDTVDWRTEGYVTPVKNQEQCGSCWS 414
           DMTNEEFR         + +   VF  P  +  LP +VDWR +GYVTPVKNQ+QCGSCW+
Sbjct: 82  DMTNEEFRQMMGCFRNQKFRKGKVFREPLFLD-LPKSVDWRKKGYVTPVKNQKQCGSCWA 140

Query: 415 FSATGSLEGQHFRKTGNLTSFSEQQLVDXXXXXXXXXXXXXLMDNAFEYI-EKFGIESED 591
           FSATG+LEGQ FRKTG L S SEQ LVD              M  AF+Y+ E  G++SE+
Sbjct: 141 FSATGALEGQMFRKTGKLVSLSEQNLVDCSRPQGNQGCNGGFMARAFQYVKENGGLDSEE 200

Query: 592 AYPYTAEDGTCLYDKSKVVGSCTGYVDIPGGSETSLATAAATVGPISVAIDASNYSFQLY 771
           +YPY A D  C Y     V + TG+  +  G E +L  A ATVGPISVA+DA + SFQ Y
Sbjct: 201 SYPYVAVDEICKYRPENSVANDTGFTVVAPGKEKALMKAVATVGPISVAMDAGHSSFQFY 260

Query: 772 KSGIYNEPDCSSTQLDHGVLVVGYGTE----DGSNYWLVKNSWGTVWGIDGYIKMSKDAN 939
           KSGIY EPDCSS  LDHGVLVVGYG E    + S YWLVKNSWG  WG +GY+K++KD N
Sbjct: 261 KSGIYFEPDCSSKNLDHGVLVVGYGFEGANSNNSKYWLVKNSWGPEWGSNGYVKIAKDKN 320

Query: 940 NQCGIATMASYPLV 981
           N CGIAT ASYP V
Sbjct: 321 NHCGIATAASYPNV 334

>sp|P07711|CATL_HUMAN Cathepsin L precursor (Major excreted protein) (MEP) [Contains:
           Cathepsin L heavy chain; Cathepsin L light chain]
          Length = 333

 Score =  317 bits (812), Expect = 4e-86
 Identities = 165/322 (51%), Positives = 204/322 (63%), Gaps = 5/322 (1%)
 Frame = +1

Query: 31  VAPHKLTVNSELNDDWESYKIKFGKKYESLNEISRRLIWESNLKYIQKHNIESDLGKHTY 210
           +A   LT +  L   W  +K    + Y    E  RR +WE N+K I+ HN E   GKH++
Sbjct: 14  IASATLTFDHSLEAQWTKWKAMHNRLYGMNEEGWRRAVWEKNMKMIELHNQEYREGKHSF 73

Query: 211 TLGLNHFADMTNEEFRAKYLSVPPSRKKISTVFMAPKNMGKLPDTVDWRTEGYVTPVKNQ 390
           T+ +N F DMT+EEFR         + +   VF  P    + P +VDWR +GYVTPVKNQ
Sbjct: 74  TMAMNAFGDMTSEEFRQVMNGFQNRKPRKGKVFQEPL-FYEAPRSVDWREKGYVTPVKNQ 132

Query: 391 EQCGSCWSFSATGSLEGQHFRKTGNLTSFSEQQLVDXXXXXXXXXXXXXLMDNAFEYI-E 567
            QCGSCW+FSATG+LEGQ FRKTG L S SEQ LVD             LMD AF+Y+ +
Sbjct: 133 GQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNGGLMDYAFQYVQD 192

Query: 568 KFGIESEDAYPYTAEDGTCLYDKSKVVGSCTGYVDIPGGSETSLATAAATVGPISVAIDA 747
             G++SE++YPY A + +C Y+    V + TG+VDIP   E +L  A ATVGPISVAIDA
Sbjct: 193 NGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIP-KQEKALMKAVATVGPISVAIDA 251

Query: 748 SNYSFQLYKSGIYNEPDCSSTQLDHGVLVVGYGTE----DGSNYWLVKNSWGTVWGIDGY 915
            + SF  YK GIY EPDCSS  +DHGVLVVGYG E    D + YWLVKNSWG  WG+ GY
Sbjct: 252 GHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKNSWGEEWGMGGY 311

Query: 916 IKMSKDANNQCGIATMASYPLV 981
           +KM+KD  N CGIA+ ASYP V
Sbjct: 312 VKMAKDRRNHCGIASAASYPTV 333

>sp|O35186|CATK_RAT Cathepsin K precursor
          Length = 329

 Score =  316 bits (810), Expect = 6e-86
 Identities = 155/324 (47%), Positives = 211/324 (65%), Gaps = 4/324 (1%)
 Frame = +1

Query: 16  FVVAHVAPHKLTVNSELNDDWESYKIKFGKKYES-LNEISRRLIWESNLKYIQKHNIESD 192
           F++  V    L+    L+  WE +K   GK+Y S ++EISRRLIWE NLK I  HN+E+ 
Sbjct: 6   FLLLPVVSFALSPEETLDTQWELWKKTHGKQYNSKVDEISRRLIWEKNLKKISVHNLEAS 65

Query: 193 LGKHTYTLGLNHFADMTNEEFRAKY--LSVPPSRKKISTVFMAPKNMGKLPDTVDWRTEG 366
           LG HTY L +NH  DMT+EE   K   L VPPSR   +     P+  G++PD++D+R +G
Sbjct: 66  LGAHTYELAMNHLGDMTSEEVVQKMTGLRVPPSRSFSNDTLYTPEWEGRVPDSIDYRKKG 125

Query: 367 YVTPVKNQEQCGSCWSFSATGSLEGQHFRKTGNLTSFSEQQLVDXXXXXXXXXXXXXLMD 546
           YVTPVKNQ QCGSCW+FS+ G+LEGQ  +KTG L + S Q LVD              M 
Sbjct: 126 YVTPVKNQGQCGSCWAFSSAGALEGQLKKKTGKLLALSPQNLVDCVSENYGCGGGY--MT 183

Query: 547 NAFEYIEKFG-IESEDAYPYTAEDGTCLYDKSKVVGSCTGYVDIPGGSETSLATAAATVG 723
            AF+Y+++ G I+SEDAYPY  +D +C+Y+ +     C GY +IP G+E +L  A A VG
Sbjct: 184 TAFQYVQQNGGIDSEDAYPYVGQDESCMYNATAKAAKCRGYREIPVGNEKALKRAVARVG 243

Query: 724 PISVAIDASNYSFQLYKSGIYNEPDCSSTQLDHGVLVVGYGTEDGSNYWLVKNSWGTVWG 903
           P+SV+IDAS  SFQ Y  G+Y + +C    ++H VLVVGYGT+ G+ YW++KNSWG  WG
Sbjct: 244 PVSVSIDASLTSFQFYSRGVYYDENCDRDNVNHAVLVVGYGTQKGNKYWIIKNSWGESWG 303

Query: 904 IDGYIKMSKDANNQCGIATMASYP 975
             GY+ ++++ NN CGI  +AS+P
Sbjct: 304 NKGYVLLARNKNNACGITNLASFP 327

>sp|Q28944|CATL_PIG Cathepsin L precursor [Contains: Cathepsin L heavy chain; Cathepsin
           L light chain]
          Length = 334

 Score =  316 bits (809), Expect = 8e-86
 Identities = 168/331 (50%), Positives = 210/331 (63%), Gaps = 6/331 (1%)
 Frame = +1

Query: 7   ALVFVVAHVAPHKLTVNSELNDDWESYKIKFGKKYESLNEISRRLIWESNLKYIQKHNIE 186
           AL   +A  AP    ++  L+ DW  +K   G+ Y    E  RR +WE N+K I+ HN E
Sbjct: 9   ALCLGIASAAPK---LDQNLDADWYKWKATHGRLYGMNEEGWRRAVWEKNMKMIELHNQE 65

Query: 187 SDLGKHTYTLGLNHFADMTNEEFRAKYLSVPPSRKKISTVFMAPKNMGKLPDTVDWRTEG 366
              GKH +++ +N F DMTNEEFR         + K   VF     + ++P +VDWR +G
Sbjct: 66  YSQGKHGFSMAMNAFGDMTNEEFRQVMNGFQNQKHKKGKVFHESLVL-EVPKSVDWREKG 124

Query: 367 YVTPVKNQEQCGSCWSFSATGSLEGQHFRKTGNLTSFSEQQLVDXXXXXXXXXXXXXLMD 546
           YVT VKNQ QCGSCW+FSATG+LEGQ FRKTG L S SEQ LVD             LMD
Sbjct: 125 YVTAVKNQGQCGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSRPQGNQGCNGGLMD 184

Query: 547 NAFEYI-EKFGIESEDAYPYTA-EDGTCLYDKSKVVGSCTGYVDIPGGSETSLATAAATV 720
           NAF+Y+ +  G+++E++YPY   E  +C Y       + TG+VDIP   E +L  A ATV
Sbjct: 185 NAFQYVKDNGGLDTEESYPYLGRETNSCTYKPECSAANDTGFVDIP-QREKALMKAVATV 243

Query: 721 GPISVAIDASNYSFQLYKSGIYNEPDCSSTQLDHGVLVVGYGTE----DGSNYWLVKNSW 888
           GPISVAIDA + SFQ YKSGIY +PDCSS  LDHGVLVVGYG E    + S +W+VKNSW
Sbjct: 244 GPISVAIDAGHSSFQFYKSGIYYDPDCSSKDLDHGVLVVGYGFEGTDSNSSKFWIVKNSW 303

Query: 889 GTVWGIDGYIKMSKDANNQCGIATMASYPLV 981
           G  WG +GY+KM+KD NN CGI+T ASYP V
Sbjct: 304 GPEWGWNGYVKMAKDQNNHCGISTAASYPTV 334

>sp|Q9GLE3|CATK_PIG Cathepsin K precursor
          Length = 330

 Score =  316 bits (809), Expect = 8e-86
 Identities = 155/308 (50%), Positives = 204/308 (66%), Gaps = 4/308 (1%)
 Frame = +1

Query: 64  LNDDWESYKIKFGKKYES-LNEISRRLIWESNLKYIQKHNIESDLGKHTYTLGLNHFADM 240
           L+  WE +K  + K+Y S ++EISRRLIWE NLK+I  HN+E+ LG HTY L +NH  DM
Sbjct: 23  LDTQWELWKKTYRKQYNSKVDEISRRLIWEKNLKHISIHNLEASLGVHTYELAMNHLGDM 82

Query: 241 TNEEFRAKY--LSVPPSRKKISTVFMAPKNMGKLPDTVDWRTEGYVTPVKNQEQCGSCWS 414
           T+EE   K   L VPPS  + +     P   G+ PD++D+R +GYVTPVKNQ QCGSCW+
Sbjct: 83  TSEEVVQKMTGLKVPPSHSRSNDTLYIPDWEGRTPDSIDYRKKGYVTPVKNQGQCGSCWA 142

Query: 415 FSATGSLEGQHFRKTGNLTSFSEQQLVDXXXXXXXXXXXXXLMDNAFEYIEKF-GIESED 591
           FS+ G+LEGQ  +KTG L + S Q LVD              M NAF+Y++K  GI+SED
Sbjct: 143 FSSVGALEGQLKKKTGKLLNLSPQNLVDCVSENDGCGGGY--MTNAFQYVQKNRGIDSED 200

Query: 592 AYPYTAEDGTCLYDKSKVVGSCTGYVDIPGGSETSLATAAATVGPISVAIDASNYSFQLY 771
           AYPY  +D  C+Y+ +     C GY +IP G+E +L  A A VGP+SVAIDAS  SFQ Y
Sbjct: 201 AYPYVGQDENCMYNPTGKAAKCRGYREIPEGNEKALKRAVARVGPVSVAIDASLTSFQFY 260

Query: 772 KSGIYNEPDCSSTQLDHGVLVVGYGTEDGSNYWLVKNSWGTVWGIDGYIKMSKDANNQCG 951
             G+Y + +C+S  L+H VL VGYG + G  +W++KNSWG  WG  GYI M+++ NN CG
Sbjct: 261 SKGVYYDENCNSDNLNHAVLAVGYGIQKGKKHWIIKNSWGENWGNKGYILMARNKNNACG 320

Query: 952 IATMASYP 975
           IA +AS+P
Sbjct: 321 IANLASFP 328

>sp|P61277|CATK_MACMU Cathepsin K precursor
 sp|P61276|CATK_MACFA Cathepsin K precursor
          Length = 329

 Score =  314 bits (804), Expect = 3e-85
 Identities = 156/308 (50%), Positives = 203/308 (65%), Gaps = 4/308 (1%)
 Frame = +1

Query: 64  LNDDWESYKIKFGKKYES-LNEISRRLIWESNLKYIQKHNIESDLGKHTYTLGLNHFADM 240
           L+  WE +K    K+Y S ++EISRRLIWE NLKYI  HN+E+ LG HTY L +NH  DM
Sbjct: 22  LDTHWELWKKTHRKQYNSKVDEISRRLIWEKNLKYISIHNLEASLGVHTYELAMNHLGDM 81

Query: 241 TNEEFRAKY--LSVPPSRKKISTVFMAPKNMGKLPDTVDWRTEGYVTPVKNQEQCGSCWS 414
           TNEE   K   L VP S  + +     P   G+ PD+VD+R +GYVTPVKNQ QCGSCW+
Sbjct: 82  TNEEVVQKMTGLKVPASHSRSNDTLYIPDWEGRAPDSVDYRKKGYVTPVKNQGQCGSCWA 141

Query: 415 FSATGSLEGQHFRKTGNLTSFSEQQLVDXXXXXXXXXXXXXLMDNAFEYIEKF-GIESED 591
           FS+ G+LEGQ  +KTG L + S Q LVD              M NAF+Y++K  GI+SED
Sbjct: 142 FSSVGALEGQLKKKTGKLLNLSPQNLVDCVSENDGCGGGY--MTNAFQYVQKNRGIDSED 199

Query: 592 AYPYTAEDGTCLYDKSKVVGSCTGYVDIPGGSETSLATAAATVGPISVAIDASNYSFQLY 771
           AYPY  ++ +C+Y+ +     C GY +IP G+E +L  A A VGP+SVAIDAS  SFQ Y
Sbjct: 200 AYPYVGQEESCMYNPTGKAAKCRGYREIPEGNEKALKRAVARVGPVSVAIDASLTSFQFY 259

Query: 772 KSGIYNEPDCSSTQLDHGVLVVGYGTEDGSNYWLVKNSWGTVWGIDGYIKMSKDANNQCG 951
             G+Y +  C+S  L+H VL VGYG + G+ +W++KNSWG  WG  GYI M+++ NN CG
Sbjct: 260 SKGVYYDESCNSDNLNHAVLAVGYGIQKGNKHWIIKNSWGENWGNKGYILMARNKNNACG 319

Query: 952 IATMASYP 975
           IA +AS+P
Sbjct: 320 IANLASFP 327

  Database: Non-redundant SwissProt sequences
    Posted date:  Dec 6, 2005  7:40 AM
  Number of letters in database: 68,354,980
  Number of sequences in database:  184,735
  
  Database: swissprot.01
    Posted date:  Dec 6, 2005  8:18 AM
  Number of letters in database: 66,202,850
  Number of sequences in database:  184,431
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 117,864,511
Number of Sequences: 369166
Number of extensions: 2479633
Number of successful extensions: 8017
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 7098
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 7441
length of database: 68,354,980
effective HSP length: 112
effective length of database: 47,664,660
effective search space used: 11391853740
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)

Cluster detail

DrC_00420

  1. Dr_sW_006_K24
  2. Dr_sW_014_C21
  3. Dr_sW_002_F17
  4. Dr_sW_027_G02
  5. Dr_sW_027_J01
  6. Dr_sW_005_N10
  7. Dr_sW_011_D13
  8. Dr_sW_026_I17
  9. Dr_sW_009_B21
  10. Dr_sW_026_A12
  11. Dr_sW_013_G24
  12. Dr_sW_027_I21
  13. Dr_sW_009_K09
  14. Dr_sW_011_L19
  15. Dr_sW_003_G15