Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= DrC_00226 (716 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|P26624|GST28_SCHJA Glutathione S-transferase 28 kDa (GST... 136 6e-32 sp|P09792|GST28_SCHMA Glutathione S-transferase 28 kDa (GST... 129 1e-29 sp|P30114|GST28_SCHHA Glutathione S-transferase 28 kDa (GST... 125 1e-28 sp|P30113|GST28_SCHBO Glutathione S-transferase 28 kDa (GST... 122 1e-27 sp|O73888|PTGD2_CHICK Glutathione-requiring prostaglandin D... 116 5e-26 sp|P91253|GST7_CAEEL Probable glutathione S-transferase 7 (... 113 6e-25 sp|P46088|GST_OMMSL Glutathione S-transferase (GST class-si... 112 1e-24 sp|O16116|GST3_CAEEL Glutathione S-transferase 3 (GST class... 110 5e-24 sp|O60760|PTGD2_HUMAN Glutathione-requiring prostaglandin D... 108 1e-23 sp|Q9JHF7|PTGD2_MOUSE Glutathione-requiring prostaglandin D... 107 2e-23
>sp|P26624|GST28_SCHJA Glutathione S-transferase 28 kDa (GST 28) (SJ28 antigen) (GST class-mu) Length = 206 Score = 136 bits (342), Expect = 6e-32 Identities = 77/204 (37%), Positives = 122/204 (59%), Gaps = 9/204 (4%) Frame = +3 Query: 9 VKVTYFNARGRAEIIRLVLKASKVEFEDVRLTKEQWVDVKPTTPTGKLPVVEYEGKK--- 179 VK+ YFN RGRAE IR++L A+ VEFED R+ + W +KPT P G+LP+V+ K+ Sbjct: 1 VKLIYFNGRGRAEPIRMILVAAGVEFEDERIEFQDWPKIKPTIPGGRLPIVKITDKRGDV 60 Query: 180 --LTQSMAIARAIARKYGFMGEDDKEYYLIERAIGQMVDVLEGMYKIYFAPEEKKEDLRT 353 +++S+AIAR IARK+ MG+ D EYY+IE+ IGQ+ DV +K P E+KE + Sbjct: 61 KTMSESLAIARFIARKHNMMGDTDDEYYIIEKMIGQVEDVESEYHKTLIKPPEEKEKISK 120 Query: 354 EFVTTSGRDNLKSLEGFIKES--GFFVGEKITLAELFFVVLTDYLEKLPK--LYDDFPKL 521 E + L+++ +KES VG+K+TLA++ + D++ L K L +P++ Sbjct: 121 EILNGKVPILLQAICETLKESTGNLTVGDKVTLADVVLIASIDHITDLDKEFLTGKYPEI 180 Query: 522 KELRERVLKANTDVEDWVKTRPVT 593 + R+ +L + + ++ R T Sbjct: 181 HKHRKHLLATSPKLAKYLSERHAT 204
>sp|P09792|GST28_SCHMA Glutathione S-transferase 28 kDa (GST 28) (SM28 antigen) (Protective 28 kDa antigen) (GST class-mu) Length = 211 Score = 129 bits (323), Expect = 1e-29 Identities = 74/204 (36%), Positives = 119/204 (58%), Gaps = 9/204 (4%) Frame = +3 Query: 9 VKVTYFNARGRAEIIRLVLKASKVEFEDVRLTKEQWVDVKPTTPTGKLPVVEYEG----- 173 +KV YF+ RGRAE IR+ L A+ V++ED R++ + W +KPT P G+LP V+ Sbjct: 6 IKVIYFDGRGRAESIRMTLVAAGVDYEDERISFQDWPKIKPTIPGGRLPAVKVTDDHGHV 65 Query: 174 KKLTQSMAIARAIARKYGFMGEDDKEYYLIERAIGQMVDVLEGMYKIYFAPEEKKEDLRT 353 K + +S+AIAR +A+K+ MGE D+EYY +E+ IGQ DV +K P+E+KE + Sbjct: 66 KWMLESLAIARYMAKKHHMMGETDEEYYSVEKLIGQAEDVEHEYHKTLMKPQEEKEKITK 125 Query: 354 EFVTTSGRDNLKSLEGFIKES--GFFVGEKITLAELFFVVLTDYLEKLPK--LYDDFPKL 521 E + L + +K S VG+K+TLA+L + + D++ L K L +P++ Sbjct: 126 EILNGKVPVLLNMICESLKGSTGKLAVGDKVTLADLVLIAVIDHVTDLDKGFLTGKYPEI 185 Query: 522 KELRERVLKANTDVEDWVKTRPVT 593 + RE +L ++ + ++ RP T Sbjct: 186 HKHRENLLASSPRLAKYLSNRPAT 209
>sp|P30114|GST28_SCHHA Glutathione S-transferase 28 kDa (GST 28) (GST class-mu) Length = 211 Score = 125 bits (314), Expect = 1e-28 Identities = 73/204 (35%), Positives = 118/204 (57%), Gaps = 9/204 (4%) Frame = +3 Query: 9 VKVTYFNARGRAEIIRLVLKASKVEFEDVRLTKEQWVDVKPTTPTGKLPVVEYEG----- 173 +KV YFN RGRAE IR+ L A+ V +ED R++ + W +KPT P G+LP V+ Sbjct: 6 IKVIYFNGRGRAESIRMTLVAAGVNYEDERISFQDWPKIKPTIPGGRLPAVKITDNHGHV 65 Query: 174 KKLTQSMAIARAIARKYGFMGEDDKEYYLIERAIGQMVDVLEGMYKIYFAPEEKKEDLRT 353 K + +S+AIAR +A+K+ MGE D+EYY +E+ IGQ+ D+ +K PEE+K+ + Sbjct: 66 KWMLESLAIARYMAKKHHMMGETDEEYYNVEKLIGQVEDLEHEYHKTLMKPEEEKQKITK 125 Query: 354 EFVTTSGRDNLKSLEGFIKES--GFFVGEKITLAELFFVVLTDYLEKLPK--LYDDFPKL 521 E + L + +K S VG+K+TLA+L + + D++ L K L +P++ Sbjct: 126 EILNGKVPVLLDIICESLKASTGKLAVGDKVTLADLVLIAVIDHVTDLDKEFLTGKYPEI 185 Query: 522 KELRERVLKANTDVEDWVKTRPVT 593 + RE +L ++ + ++ R T Sbjct: 186 HKHRENLLASSPRLAKYLSDRAAT 209
>sp|P30113|GST28_SCHBO Glutathione S-transferase 28 kDa (GST 28) (GST class-mu) Length = 211 Score = 122 bits (305), Expect = 1e-27 Identities = 72/204 (35%), Positives = 116/204 (56%), Gaps = 9/204 (4%) Frame = +3 Query: 9 VKVTYFNARGRAEIIRLVLKASKVEFEDVRLTKEQWVDVKPTTPTGKLPVVEYEG----- 173 +KV YFN RGRAE IR+ L A+ V +ED R++ + W +KPT P G+LP V+ Sbjct: 6 IKVIYFNGRGRAESIRMTLVAAGVNYEDERISFQDWPKIKPTIPGGRLPAVKITDNHGHV 65 Query: 174 KKLTQSMAIARAIARKYGFMGEDDKEYYLIERAIGQMVDVLEGMYKIYFAPEEKKEDLRT 353 K + +S+AIAR +A+K+ MG ++EYY +E+ IGQ D+ YK PEE+K+ + Sbjct: 66 KWMVESLAIARYMAKKHHMMGGTEEEYYNVEKLIGQAEDLEHEYYKTLMKPEEEKQKIIK 125 Query: 354 EFVTTSGRDNLKSLEGFIKES--GFFVGEKITLAELFFVVLTDYLEKLPK--LYDDFPKL 521 E + L + +K S VG+K+TLA+L + + D++ L K L +P++ Sbjct: 126 EILNGKVPVLLDIICESLKASTGKLAVGDKVTLADLVLIAVIDHVTDLDKEFLTGKYPEI 185 Query: 522 KELRERVLKANTDVEDWVKTRPVT 593 + RE +L ++ + ++ R T Sbjct: 186 HKHRENLLASSPRLAKYLSDRAAT 209
>sp|O73888|PTGD2_CHICK Glutathione-requiring prostaglandin D synthase (Glutathione-dependent PGD synthetase) (Prostaglandin-H2 D-isomerase) (Hematopoietic prostaglandin D synthase) (H-PGDS) Length = 199 Score = 116 bits (291), Expect = 5e-26 Identities = 69/199 (34%), Positives = 112/199 (56%), Gaps = 5/199 (2%) Frame = +3 Query: 12 KVTYFNARGRAEIIRLVLKASKVEFEDVRLTKEQWVDVKPTTPTGKLPVVEYEGKKLTQS 191 K+TYFN RGRAEI R + + +++ED RL W +KPT P GK+P++E +G + QS Sbjct: 5 KLTYFNLRGRAEICRYLFAYAGIKYEDHRLEGADWPKIKPTIPFGKVPILEVDGVIIHQS 64 Query: 192 MAIARAIARKYGFMGEDDKEYYLIERAIGQMVDVLEGMYKIYFAPEEKKEDLR----TEF 359 +AIAR +AR+ G G+ E L + + + D + + F EK +D++ + Sbjct: 65 LAIARYLARESGLAGQTPVEQALADAIVDTIDD-----FMMLFPWAEKNQDVKEKAFNDI 119 Query: 360 VTTSGRDNLKSLEGFIKESGFFVGEKITLAELFF-VVLTDYLEKLPKLYDDFPKLKELRE 536 +T + LK L+ F+ + +FVG+ +T A+ ++ V T L L D +P+L LR+ Sbjct: 120 LTNKAPELLKDLDTFLGDKKWFVGKSVTWADFYWDVCSTTLLSYKADLADKYPRLLALRD 179 Query: 537 RVLKANTDVEDWVKTRPVT 593 RV +A + W++ RP T Sbjct: 180 RV-EALPAIAAWIQKRPKT 197
>sp|P91253|GST7_CAEEL Probable glutathione S-transferase 7 (GST class-sigma) Length = 206 Score = 113 bits (282), Expect = 6e-25 Identities = 74/202 (36%), Positives = 110/202 (54%), Gaps = 8/202 (3%) Frame = +3 Query: 12 KVTYFNARGRAEIIRLVLKASKVEFEDVRLTKEQWVDVKPTTPTGKLPVVEYEGKKLTQS 191 KV+YF RG EI R +L + +FED R+ KE+W VKP+TP G+LP++E +GK L QS Sbjct: 5 KVSYFPIRGAGEIARQILAYAGQDFEDNRIPKEEWPAVKPSTPFGQLPLLEVDGKVLAQS 64 Query: 192 MAIARAIARKYGFMGEDDKEYYLIERAIGQMVDVLEG-----MYKIYFAPEEKKEDLRTE 356 AIAR +AR++G G+ E + Q D L M K+ FA E + L + Sbjct: 65 HAIARYLARQFGINGKCAWEEAQVNSVADQFKDYLNEVRPYFMVKMGFA-EGDLDALAKD 123 Query: 357 FVTTSGRDNLKSLEGFIKE--SGFFVGEKITLAELFFVVLT-DYLEKLPKLYDDFPKLKE 527 + + F+K SG+ VG+ +T +L T D L L D+FP+ K Sbjct: 124 VFLPGFKKHYGFFANFLKSAGSGYLVGDSLTFVDLLVAQHTADLLAANAALLDEFPQFKA 183 Query: 528 LRERVLKANTDVEDWVKTRPVT 593 +E+V +N +++ W++TRPVT Sbjct: 184 HQEKV-HSNANIKKWLETRPVT 204
>sp|P46088|GST_OMMSL Glutathione S-transferase (GST class-sigma) Length = 203 Score = 112 bits (279), Expect = 1e-24 Identities = 71/197 (36%), Positives = 108/197 (54%), Gaps = 5/197 (2%) Frame = +3 Query: 21 YFNARGRAEIIRLVLKASKVEFEDVRLTKEQWVDVKPTTPTGKLPVVEYEGKKLTQSMAI 200 YF GRAE+ R VL A EF D + W ++K T + +PV++ +G K++QSM I Sbjct: 8 YFPLMGRAELCRFVLAAHGEEFTDRVVEMADWPNLKATMYSNAMPVLDIDGTKMSQSMCI 67 Query: 201 ARAIARKYGFMGEDDKEYYLIERAIGQMVDVLEGMYKIYFAPEEKKEDLRTEFVTTSGRD 380 AR +AR++G G+ E Y ++ + D+ + KI FAPE KE ++ + + R Sbjct: 68 ARHLAREFGLDGKTSLEKYRVDEITETLQDIFNDVVKIKFAPEAAKEAVQQNYEKSCKR- 126 Query: 381 NLKSLEGFIKES----GFFVGEKITLAELF-FVVLTDYLEKLPKLYDDFPKLKELRERVL 545 LEG + + GFFVG +TLA+L +V L L+ P+L D PK+ LR+RV Sbjct: 127 LAPFLEGLLVSNGGGDGFFVGNSMTLADLHCYVALEVPLKHTPELLKDCPKIVALRKRVA 186 Query: 546 KANTDVEDWVKTRPVTD 596 + + ++K RPV D Sbjct: 187 EC-PKIAAYLKKRPVRD 202
>sp|O16116|GST3_CAEEL Glutathione S-transferase 3 (GST class-sigma) (CeGST3) Length = 207 Score = 110 bits (274), Expect = 5e-24 Identities = 70/205 (34%), Positives = 119/205 (58%), Gaps = 11/205 (5%) Frame = +3 Query: 12 KVTYFNARGRAEIIRLVLKASKVEFEDVRLTKEQWVDVKPTTPTGKLPVVEYEGKKLTQS 191 K+TYFNARG AEI R + + VEFED R+ +E++ +KPT P+G++P++ +G + +QS Sbjct: 5 KLTYFNARGLAEISRQLFHMAGVEFEDERINEEKFSQLKPTFPSGQVPILCIDGAQFSQS 64 Query: 192 MAIARAIARKYGFMGEDDKEYYLIERAIGQMVDVLEGMYKIYFA-----PEEKKEDLRTE 356 AIAR +ARK+GF+G+ +E + + D +E K A EE +++R E Sbjct: 65 TAIARYLARKFGFVGQTAEEELQADEVVDTFKDFIESFRKFVIAVLSGESEEILKNIREE 124 Query: 357 FVTTSGRDNLKSLEGFIKE--SGFFVGEKITLAELFFVVLTDYLEKL--PKLYD--DFPK 518 + + + L+ +++ SG+ VG ++T A+L V+ D L L +L D + Sbjct: 125 VIKPAVKTYTAYLKAILEKSSSGYLVGNELTWADL---VIADNLTTLINAELLDIENDKL 181 Query: 519 LKELRERVLKANTDVEDWVKTRPVT 593 LKE RE++++ +++W+ RP T Sbjct: 182 LKEFREKIIE-TPKLKEWLAKRPET 205
>sp|O60760|PTGD2_HUMAN Glutathione-requiring prostaglandin D synthase (Glutathione-dependent PGD synthetase) (Prostaglandin-H2 D-isomerase) (Hematopoietic prostaglandin D synthase) (H-PGDS) Length = 199 Score = 108 bits (271), Expect = 1e-23 Identities = 64/200 (32%), Positives = 110/200 (55%), Gaps = 4/200 (2%) Frame = +3 Query: 12 KVTYFNARGRAEIIRLVLKASKVEFEDVRLTKEQWVDVKPTTPTGKLPVVEYEGKKLTQS 191 K+TYFN RGRAEIIR + +++ED R+ + W ++K T P GK+P++E +G L QS Sbjct: 5 KLTYFNMRGRAEIIRYIFAYLDIQYEDHRIEQADWPEIKSTLPFGKIPILEVDGLTLHQS 64 Query: 192 MAIARAIARKYGFMGEDDKEYYLIERAIGQMVDVLEGMYKIYFAPEEK---KEDLRTEFV 362 +AIAR + + G + E + + +VD L+ + E+K KE + E + Sbjct: 65 LAIARYLTKNTDLAGNTEME----QCHVDAIVDTLDDFMSCFPWAEKKQDVKEQMFNELL 120 Query: 363 TTSGRDNLKSLEGFIKESGFFVGEKITLAELFF-VVLTDYLEKLPKLYDDFPKLKELRER 539 T + ++ L+ ++ + +G +T A+ ++ + T L P L D+ P+L LR++ Sbjct: 121 TYNAPHLMQDLDTYLGGREWLIGNSVTWADFYWEICSTTLLVFKPDLLDNHPRLVTLRKK 180 Query: 540 VLKANTDVEDWVKTRPVTDM 599 V +A V +W+K RP T + Sbjct: 181 V-QAIPAVANWIKRRPQTKL 199
>sp|Q9JHF7|PTGD2_MOUSE Glutathione-requiring prostaglandin D synthase (Glutathione-dependent PGD synthetase) (Prostaglandin-H2 D-isomerase) (Hematopoietic prostaglandin D synthase) (H-PGDS) Length = 199 Score = 107 bits (268), Expect = 2e-23 Identities = 63/197 (31%), Positives = 105/197 (53%), Gaps = 1/197 (0%) Frame = +3 Query: 12 KVTYFNARGRAEIIRLVLKASKVEFEDVRLTKEQWVDVKPTTPTGKLPVVEYEGKKLTQS 191 K+ YFN RGRAEIIR + +++ED R+ + W +KPT P GK+PV+E EG + QS Sbjct: 5 KLLYFNMRGRAEIIRYIFAYLDIKYEDHRIEQADWPKIKPTLPFGKIPVLEVEGLTIHQS 64 Query: 192 MAIARAIARKYGFMGEDDKEYYLIERAIGQMVDVLEGMYKIYFAPEEKKEDLRTEFVTTS 371 +AIAR + + G+ E + + + D + ++ ++ KE + E +T Sbjct: 65 LAIARYLTKNTDLAGKTALEQCQADAVVDTLDDFM-SLFPWAEKDQDLKERMFNELLTHQ 123 Query: 372 GRDNLKSLEGFIKESGFFVGEKITLAELFF-VVLTDYLEKLPKLYDDFPKLKELRERVLK 548 LK L+ ++ + +F+G +T A+ ++ + T L P L D +PKL LR +V + Sbjct: 124 APRLLKDLDTYLGDKEWFIGNYVTWADFYWDICSTTLLVLKPGLLDIYPKLVSLRNKV-Q 182 Query: 549 ANTDVEDWVKTRPVTDM 599 A + W+ RP T + Sbjct: 183 AIPAISAWILKRPQTKL 199
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 73,851,351 Number of Sequences: 369166 Number of extensions: 1501216 Number of successful extensions: 5122 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 4876 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 5029 length of database: 68,354,980 effective HSP length: 107 effective length of database: 48,588,335 effective search space used: 6365071885 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)