Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_003_G21
(630 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P26624|GST28_SCHJA Glutathione S-transferase 28 kDa (GST... 130 4e-30
sp|P09792|GST28_SCHMA Glutathione S-transferase 28 kDa (GST... 122 1e-27
sp|P30114|GST28_SCHHA Glutathione S-transferase 28 kDa (GST... 118 1e-26
sp|P30113|GST28_SCHBO Glutathione S-transferase 28 kDa (GST... 115 1e-25
sp|O73888|PTGD2_CHICK Glutathione-requiring prostaglandin D... 109 5e-24
sp|P46088|GST_OMMSL Glutathione S-transferase (GST class-si... 109 7e-24
sp|P91253|GST7_CAEEL Probable glutathione S-transferase 7 (... 106 4e-23
sp|O16116|GST3_CAEEL Glutathione S-transferase 3 (GST class... 103 5e-22
sp|Q9JHF7|PTGD2_MOUSE Glutathione-requiring prostaglandin D... 103 5e-22
sp|O35543|PTGD2_RAT Glutathione-requiring prostaglandin D s... 102 6e-22
>sp|P26624|GST28_SCHJA Glutathione S-transferase 28 kDa (GST 28) (SJ28 antigen) (GST
class-mu)
Length = 206
Score = 130 bits (326), Expect = 4e-30
Identities = 74/199 (37%), Positives = 118/199 (59%), Gaps = 9/199 (4%)
Frame = +3
Query: 3 FNARGRAEIIRLVLKASKVEFEDVRLTKEQWVDVKPTTPTGKLPVVEYEGKK-----LTQ 167
FN RGRAE IR++L A+ VEFED R+ + W +KPT P G+LP+V+ K+ +++
Sbjct: 6 FNGRGRAEPIRMILVAAGVEFEDERIEFQDWPKIKPTIPGGRLPIVKITDKRGDVKTMSE 65
Query: 168 SMAIARAIARKYGFMGEDDKEYYLIERAIGQMVDVLEGMYKIYFAPEEKKEDLRTEFVTT 347
S+AIAR IARK+ MG+ D EYY+IE+ IGQ+ DV +K P E+KE + E +
Sbjct: 66 SLAIARFIARKHNMMGDTDDEYYIIEKMIGQVEDVESEYHKTLIKPPEEKEKISKEILNG 125
Query: 348 SGRDNLKSLEGFIKES--GFFVGEKITLAELFFVVLTDYLEKLPK--LYDDFPKLKELRE 515
L+++ +KES VG+K+TLA++ + D++ L K L +P++ + R+
Sbjct: 126 KVPILLQAICETLKESTGNLTVGDKVTLADVVLIASIDHITDLDKEFLTGKYPEIHKHRK 185
Query: 516 RVLKANTDVEDWVKTRPVT 572
+L + + ++ R T
Sbjct: 186 HLLATSPKLAKYLSERHAT 204
>sp|P09792|GST28_SCHMA Glutathione S-transferase 28 kDa (GST 28) (SM28 antigen)
(Protective 28 kDa antigen) (GST class-mu)
Length = 211
Score = 122 bits (305), Expect = 1e-27
Identities = 71/199 (35%), Positives = 115/199 (57%), Gaps = 9/199 (4%)
Frame = +3
Query: 3 FNARGRAEIIRLVLKASKVEFEDVRLTKEQWVDVKPTTPTGKLPVVEYEG-----KKLTQ 167
F+ RGRAE IR+ L A+ V++ED R++ + W +KPT P G+LP V+ K + +
Sbjct: 11 FDGRGRAESIRMTLVAAGVDYEDERISFQDWPKIKPTIPGGRLPAVKVTDDHGHVKWMLE 70
Query: 168 SMAIARAIARKYGFMGEDDKEYYLIERAIGQMVDVLEGMYKIYFAPEEKKEDLRTEFVTT 347
S+AIAR +A+K+ MGE D+EYY +E+ IGQ DV +K P+E+KE + E +
Sbjct: 71 SLAIARYMAKKHHMMGETDEEYYSVEKLIGQAEDVEHEYHKTLMKPQEEKEKITKEILNG 130
Query: 348 SGRDNLKSLEGFIKES--GFFVGEKITLAELFFVVLTDYLEKLPK--LYDDFPKLKELRE 515
L + +K S VG+K+TLA+L + + D++ L K L +P++ + RE
Sbjct: 131 KVPVLLNMICESLKGSTGKLAVGDKVTLADLVLIAVIDHVTDLDKGFLTGKYPEIHKHRE 190
Query: 516 RVLKANTDVEDWVKTRPVT 572
+L ++ + ++ RP T
Sbjct: 191 NLLASSPRLAKYLSNRPAT 209
>sp|P30114|GST28_SCHHA Glutathione S-transferase 28 kDa (GST 28) (GST class-mu)
Length = 211
Score = 118 bits (296), Expect = 1e-26
Identities = 70/199 (35%), Positives = 114/199 (57%), Gaps = 9/199 (4%)
Frame = +3
Query: 3 FNARGRAEIIRLVLKASKVEFEDVRLTKEQWVDVKPTTPTGKLPVVEYEG-----KKLTQ 167
FN RGRAE IR+ L A+ V +ED R++ + W +KPT P G+LP V+ K + +
Sbjct: 11 FNGRGRAESIRMTLVAAGVNYEDERISFQDWPKIKPTIPGGRLPAVKITDNHGHVKWMLE 70
Query: 168 SMAIARAIARKYGFMGEDDKEYYLIERAIGQMVDVLEGMYKIYFAPEEKKEDLRTEFVTT 347
S+AIAR +A+K+ MGE D+EYY +E+ IGQ+ D+ +K PEE+K+ + E +
Sbjct: 71 SLAIARYMAKKHHMMGETDEEYYNVEKLIGQVEDLEHEYHKTLMKPEEEKQKITKEILNG 130
Query: 348 SGRDNLKSLEGFIKES--GFFVGEKITLAELFFVVLTDYLEKLPK--LYDDFPKLKELRE 515
L + +K S VG+K+TLA+L + + D++ L K L +P++ + RE
Sbjct: 131 KVPVLLDIICESLKASTGKLAVGDKVTLADLVLIAVIDHVTDLDKEFLTGKYPEIHKHRE 190
Query: 516 RVLKANTDVEDWVKTRPVT 572
+L ++ + ++ R T
Sbjct: 191 NLLASSPRLAKYLSDRAAT 209
>sp|P30113|GST28_SCHBO Glutathione S-transferase 28 kDa (GST 28) (GST class-mu)
Length = 211
Score = 115 bits (287), Expect = 1e-25
Identities = 69/199 (34%), Positives = 112/199 (56%), Gaps = 9/199 (4%)
Frame = +3
Query: 3 FNARGRAEIIRLVLKASKVEFEDVRLTKEQWVDVKPTTPTGKLPVVEYEG-----KKLTQ 167
FN RGRAE IR+ L A+ V +ED R++ + W +KPT P G+LP V+ K + +
Sbjct: 11 FNGRGRAESIRMTLVAAGVNYEDERISFQDWPKIKPTIPGGRLPAVKITDNHGHVKWMVE 70
Query: 168 SMAIARAIARKYGFMGEDDKEYYLIERAIGQMVDVLEGMYKIYFAPEEKKEDLRTEFVTT 347
S+AIAR +A+K+ MG ++EYY +E+ IGQ D+ YK PEE+K+ + E +
Sbjct: 71 SLAIARYMAKKHHMMGGTEEEYYNVEKLIGQAEDLEHEYYKTLMKPEEEKQKIIKEILNG 130
Query: 348 SGRDNLKSLEGFIKES--GFFVGEKITLAELFFVVLTDYLEKLPK--LYDDFPKLKELRE 515
L + +K S VG+K+TLA+L + + D++ L K L +P++ + RE
Sbjct: 131 KVPVLLDIICESLKASTGKLAVGDKVTLADLVLIAVIDHVTDLDKEFLTGKYPEIHKHRE 190
Query: 516 RVLKANTDVEDWVKTRPVT 572
+L ++ + ++ R T
Sbjct: 191 NLLASSPRLAKYLSDRAAT 209
>sp|O73888|PTGD2_CHICK Glutathione-requiring prostaglandin D synthase
(Glutathione-dependent PGD synthetase) (Prostaglandin-H2
D-isomerase) (Hematopoietic prostaglandin D synthase)
(H-PGDS)
Length = 199
Score = 109 bits (273), Expect = 5e-24
Identities = 66/195 (33%), Positives = 108/195 (55%), Gaps = 5/195 (2%)
Frame = +3
Query: 3 FNARGRAEIIRLVLKASKVEFEDVRLTKEQWVDVKPTTPTGKLPVVEYEGKKLTQSMAIA 182
FN RGRAEI R + + +++ED RL W +KPT P GK+P++E +G + QS+AIA
Sbjct: 9 FNLRGRAEICRYLFAYAGIKYEDHRLEGADWPKIKPTIPFGKVPILEVDGVIIHQSLAIA 68
Query: 183 RAIARKYGFMGEDDKEYYLIERAIGQMVDVLEGMYKIYFAPEEKKEDLR----TEFVTTS 350
R +AR+ G G+ E L + + + D + + F EK +D++ + +T
Sbjct: 69 RYLARESGLAGQTPVEQALADAIVDTIDD-----FMMLFPWAEKNQDVKEKAFNDILTNK 123
Query: 351 GRDNLKSLEGFIKESGFFVGEKITLAELFF-VVLTDYLEKLPKLYDDFPKLKELRERVLK 527
+ LK L+ F+ + +FVG+ +T A+ ++ V T L L D +P+L LR+RV +
Sbjct: 124 APELLKDLDTFLGDKKWFVGKSVTWADFYWDVCSTTLLSYKADLADKYPRLLALRDRV-E 182
Query: 528 ANTDVEDWVKTRPVT 572
A + W++ RP T
Sbjct: 183 ALPAIAAWIQKRPKT 197
>sp|P46088|GST_OMMSL Glutathione S-transferase (GST class-sigma)
Length = 203
Score = 109 bits (272), Expect = 7e-24
Identities = 70/196 (35%), Positives = 107/196 (54%), Gaps = 5/196 (2%)
Frame = +3
Query: 3 FNARGRAEIIRLVLKASKVEFEDVRLTKEQWVDVKPTTPTGKLPVVEYEGKKLTQSMAIA 182
F GRAE+ R VL A EF D + W ++K T + +PV++ +G K++QSM IA
Sbjct: 9 FPLMGRAELCRFVLAAHGEEFTDRVVEMADWPNLKATMYSNAMPVLDIDGTKMSQSMCIA 68
Query: 183 RAIARKYGFMGEDDKEYYLIERAIGQMVDVLEGMYKIYFAPEEKKEDLRTEFVTTSGRDN 362
R +AR++G G+ E Y ++ + D+ + KI FAPE KE ++ + + R
Sbjct: 69 RHLAREFGLDGKTSLEKYRVDEITETLQDIFNDVVKIKFAPEAAKEAVQQNYEKSCKR-L 127
Query: 363 LKSLEGFIKES----GFFVGEKITLAELF-FVVLTDYLEKLPKLYDDFPKLKELRERVLK 527
LEG + + GFFVG +TLA+L +V L L+ P+L D PK+ LR+RV +
Sbjct: 128 APFLEGLLVSNGGGDGFFVGNSMTLADLHCYVALEVPLKHTPELLKDCPKIVALRKRVAE 187
Query: 528 ANTDVEDWVKTRPVTD 575
+ ++K RPV D
Sbjct: 188 C-PKIAAYLKKRPVRD 202
>sp|P91253|GST7_CAEEL Probable glutathione S-transferase 7 (GST class-sigma)
Length = 206
Score = 106 bits (265), Expect = 4e-23
Identities = 71/198 (35%), Positives = 106/198 (53%), Gaps = 8/198 (4%)
Frame = +3
Query: 3 FNARGRAEIIRLVLKASKVEFEDVRLTKEQWVDVKPTTPTGKLPVVEYEGKKLTQSMAIA 182
F RG EI R +L + +FED R+ KE+W VKP+TP G+LP++E +GK L QS AIA
Sbjct: 9 FPIRGAGEIARQILAYAGQDFEDNRIPKEEWPAVKPSTPFGQLPLLEVDGKVLAQSHAIA 68
Query: 183 RAIARKYGFMGEDDKEYYLIERAIGQMVDVLEG-----MYKIYFAPEEKKEDLRTEFVTT 347
R +AR++G G+ E + Q D L M K+ FA E + L +
Sbjct: 69 RYLARQFGINGKCAWEEAQVNSVADQFKDYLNEVRPYFMVKMGFA-EGDLDALAKDVFLP 127
Query: 348 SGRDNLKSLEGFIKE--SGFFVGEKITLAELFFVVLT-DYLEKLPKLYDDFPKLKELRER 518
+ + F+K SG+ VG+ +T +L T D L L D+FP+ K +E+
Sbjct: 128 GFKKHYGFFANFLKSAGSGYLVGDSLTFVDLLVAQHTADLLAANAALLDEFPQFKAHQEK 187
Query: 519 VLKANTDVEDWVKTRPVT 572
V +N +++ W++TRPVT
Sbjct: 188 V-HSNANIKKWLETRPVT 204
>sp|O16116|GST3_CAEEL Glutathione S-transferase 3 (GST class-sigma) (CeGST3)
Length = 207
Score = 103 bits (256), Expect = 5e-22
Identities = 67/201 (33%), Positives = 115/201 (57%), Gaps = 11/201 (5%)
Frame = +3
Query: 3 FNARGRAEIIRLVLKASKVEFEDVRLTKEQWVDVKPTTPTGKLPVVEYEGKKLTQSMAIA 182
FNARG AEI R + + VEFED R+ +E++ +KPT P+G++P++ +G + +QS AIA
Sbjct: 9 FNARGLAEISRQLFHMAGVEFEDERINEEKFSQLKPTFPSGQVPILCIDGAQFSQSTAIA 68
Query: 183 RAIARKYGFMGEDDKEYYLIERAIGQMVDVLEGMYKIYFA-----PEEKKEDLRTEFVTT 347
R +ARK+GF+G+ +E + + D +E K A EE +++R E +
Sbjct: 69 RYLARKFGFVGQTAEEELQADEVVDTFKDFIESFRKFVIAVLSGESEEILKNIREEVIKP 128
Query: 348 SGRDNLKSLEGFIKE--SGFFVGEKITLAELFFVVLTDYLEKL--PKLYD--DFPKLKEL 509
+ + L+ +++ SG+ VG ++T A+L V+ D L L +L D + LKE
Sbjct: 129 AVKTYTAYLKAILEKSSSGYLVGNELTWADL---VIADNLTTLINAELLDIENDKLLKEF 185
Query: 510 RERVLKANTDVEDWVKTRPVT 572
RE++++ +++W+ RP T
Sbjct: 186 REKIIE-TPKLKEWLAKRPET 205
>sp|Q9JHF7|PTGD2_MOUSE Glutathione-requiring prostaglandin D synthase
(Glutathione-dependent PGD synthetase) (Prostaglandin-H2
D-isomerase) (Hematopoietic prostaglandin D synthase)
(H-PGDS)
Length = 199
Score = 103 bits (256), Expect = 5e-22
Identities = 61/193 (31%), Positives = 102/193 (52%), Gaps = 1/193 (0%)
Frame = +3
Query: 3 FNARGRAEIIRLVLKASKVEFEDVRLTKEQWVDVKPTTPTGKLPVVEYEGKKLTQSMAIA 182
FN RGRAEIIR + +++ED R+ + W +KPT P GK+PV+E EG + QS+AIA
Sbjct: 9 FNMRGRAEIIRYIFAYLDIKYEDHRIEQADWPKIKPTLPFGKIPVLEVEGLTIHQSLAIA 68
Query: 183 RAIARKYGFMGEDDKEYYLIERAIGQMVDVLEGMYKIYFAPEEKKEDLRTEFVTTSGRDN 362
R + + G+ E + + + D + ++ ++ KE + E +T
Sbjct: 69 RYLTKNTDLAGKTALEQCQADAVVDTLDDFM-SLFPWAEKDQDLKERMFNELLTHQAPRL 127
Query: 363 LKSLEGFIKESGFFVGEKITLAELFF-VVLTDYLEKLPKLYDDFPKLKELRERVLKANTD 539
LK L+ ++ + +F+G +T A+ ++ + T L P L D +PKL LR +V +A
Sbjct: 128 LKDLDTYLGDKEWFIGNYVTWADFYWDICSTTLLVLKPGLLDIYPKLVSLRNKV-QAIPA 186
Query: 540 VEDWVKTRPVTDM 578
+ W+ RP T +
Sbjct: 187 ISAWILKRPQTKL 199
>sp|O35543|PTGD2_RAT Glutathione-requiring prostaglandin D synthase
(Glutathione-dependent PGD synthetase) (Prostaglandin-H2
D-isomerase) (Hematopoietic prostaglandin D synthase)
(H-PGDS)
Length = 199
Score = 102 bits (255), Expect = 6e-22
Identities = 63/196 (32%), Positives = 103/196 (52%), Gaps = 4/196 (2%)
Frame = +3
Query: 3 FNARGRAEIIRLVLKASKVEFEDVRLTKEQWVDVKPTTPTGKLPVVEYEGKKLTQSMAIA 182
FN RGRAEIIR + +++ED R+ + W +KPT P GK+PV+E EG L QS+AIA
Sbjct: 9 FNMRGRAEIIRYIFAYLDIKYEDHRIEQADWPKIKPTLPFGKIPVLEVEGLTLHQSLAIA 68
Query: 183 RAIARKYGFMGEDDKEYYLIERAIGQMVDVLEGMYKIYFAPEEK---KEDLRTEFVTTSG 353
R + + G+ + E + + +VD L+ ++ EE KE + +T
Sbjct: 69 RYLTKNTDLAGKTELE----QCQVDAVVDTLDDFMSLFPWAEENQDLKERTFNDLLTRQA 124
Query: 354 RDNLKSLEGFIKESGFFVGEKITLAELFF-VVLTDYLEKLPKLYDDFPKLKELRERVLKA 530
LK L+ ++ + +F+G +T A+ ++ + T L P L +P+L LR +V +A
Sbjct: 125 PHLLKDLDTYLGDKEWFIGNYVTWADFYWDICSTTLLVLKPDLLGIYPRLVSLRNKV-QA 183
Query: 531 NTDVEDWVKTRPVTDM 578
+ W+ RP T +
Sbjct: 184 IPAISAWILKRPQTKL 199
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 70,568,420
Number of Sequences: 369166
Number of extensions: 1462156
Number of successful extensions: 5083
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4851
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5002
length of database: 68,354,980
effective HSP length: 106
effective length of database: 48,773,070
effective search space used: 5023626210
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)