Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_006_I22
(651 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P26624|GST28_SCHJA Glutathione S-transferase 28 kDa (GST... 136 5e-32
sp|P09792|GST28_SCHMA Glutathione S-transferase 28 kDa (GST... 129 9e-30
sp|P30114|GST28_SCHHA Glutathione S-transferase 28 kDa (GST... 125 1e-28
sp|P30113|GST28_SCHBO Glutathione S-transferase 28 kDa (GST... 122 1e-27
sp|O73888|PTGD2_CHICK Glutathione-requiring prostaglandin D... 116 4e-26
sp|P91253|GST7_CAEEL Probable glutathione S-transferase 7 (... 113 5e-25
sp|P46088|GST_OMMSL Glutathione S-transferase (GST class-si... 112 1e-24
sp|O16116|GST3_CAEEL Glutathione S-transferase 3 (GST class... 110 4e-24
sp|O60760|PTGD2_HUMAN Glutathione-requiring prostaglandin D... 108 9e-24
sp|Q9JHF7|PTGD2_MOUSE Glutathione-requiring prostaglandin D... 107 2e-23
>sp|P26624|GST28_SCHJA Glutathione S-transferase 28 kDa (GST 28) (SJ28 antigen) (GST
class-mu)
Length = 206
Score = 136 bits (342), Expect = 5e-32
Identities = 77/204 (37%), Positives = 122/204 (59%), Gaps = 9/204 (4%)
Frame = +3
Query: 9 VKVTYFNARGRAEIIRLVLKASKVEFEDVRLTKEQWVDVKPTTPTGKLPVVEYEGKK--- 179
VK+ YFN RGRAE IR++L A+ VEFED R+ + W +KPT P G+LP+V+ K+
Sbjct: 1 VKLIYFNGRGRAEPIRMILVAAGVEFEDERIEFQDWPKIKPTIPGGRLPIVKITDKRGDV 60
Query: 180 --LTQSMAIARAIARKYGFMGEDDKEYYLIERAIGQMVDVLEGMYKIYFAPEEKKEDLRT 353
+++S+AIAR IARK+ MG+ D EYY+IE+ IGQ+ DV +K P E+KE +
Sbjct: 61 KTMSESLAIARFIARKHNMMGDTDDEYYIIEKMIGQVEDVESEYHKTLIKPPEEKEKISK 120
Query: 354 EFVTTSGRDNLKSLEGFIKES--GFFVGEKITLAELFFVVLTDYLEKLPK--LYDDFPKL 521
E + L+++ +KES VG+K+TLA++ + D++ L K L +P++
Sbjct: 121 EILNGKVPILLQAICETLKESTGNLTVGDKVTLADVVLIASIDHITDLDKEFLTGKYPEI 180
Query: 522 KELRERVLKANTDVEDWVKTRPVT 593
+ R+ +L + + ++ R T
Sbjct: 181 HKHRKHLLATSPKLAKYLSERHAT 204
>sp|P09792|GST28_SCHMA Glutathione S-transferase 28 kDa (GST 28) (SM28 antigen)
(Protective 28 kDa antigen) (GST class-mu)
Length = 211
Score = 129 bits (323), Expect = 9e-30
Identities = 74/204 (36%), Positives = 119/204 (58%), Gaps = 9/204 (4%)
Frame = +3
Query: 9 VKVTYFNARGRAEIIRLVLKASKVEFEDVRLTKEQWVDVKPTTPTGKLPVVEYEG----- 173
+KV YF+ RGRAE IR+ L A+ V++ED R++ + W +KPT P G+LP V+
Sbjct: 6 IKVIYFDGRGRAESIRMTLVAAGVDYEDERISFQDWPKIKPTIPGGRLPAVKVTDDHGHV 65
Query: 174 KKLTQSMAIARAIARKYGFMGEDDKEYYLIERAIGQMVDVLEGMYKIYFAPEEKKEDLRT 353
K + +S+AIAR +A+K+ MGE D+EYY +E+ IGQ DV +K P+E+KE +
Sbjct: 66 KWMLESLAIARYMAKKHHMMGETDEEYYSVEKLIGQAEDVEHEYHKTLMKPQEEKEKITK 125
Query: 354 EFVTTSGRDNLKSLEGFIKES--GFFVGEKITLAELFFVVLTDYLEKLPK--LYDDFPKL 521
E + L + +K S VG+K+TLA+L + + D++ L K L +P++
Sbjct: 126 EILNGKVPVLLNMICESLKGSTGKLAVGDKVTLADLVLIAVIDHVTDLDKGFLTGKYPEI 185
Query: 522 KELRERVLKANTDVEDWVKTRPVT 593
+ RE +L ++ + ++ RP T
Sbjct: 186 HKHRENLLASSPRLAKYLSNRPAT 209
>sp|P30114|GST28_SCHHA Glutathione S-transferase 28 kDa (GST 28) (GST class-mu)
Length = 211
Score = 125 bits (314), Expect = 1e-28
Identities = 73/204 (35%), Positives = 118/204 (57%), Gaps = 9/204 (4%)
Frame = +3
Query: 9 VKVTYFNARGRAEIIRLVLKASKVEFEDVRLTKEQWVDVKPTTPTGKLPVVEYEG----- 173
+KV YFN RGRAE IR+ L A+ V +ED R++ + W +KPT P G+LP V+
Sbjct: 6 IKVIYFNGRGRAESIRMTLVAAGVNYEDERISFQDWPKIKPTIPGGRLPAVKITDNHGHV 65
Query: 174 KKLTQSMAIARAIARKYGFMGEDDKEYYLIERAIGQMVDVLEGMYKIYFAPEEKKEDLRT 353
K + +S+AIAR +A+K+ MGE D+EYY +E+ IGQ+ D+ +K PEE+K+ +
Sbjct: 66 KWMLESLAIARYMAKKHHMMGETDEEYYNVEKLIGQVEDLEHEYHKTLMKPEEEKQKITK 125
Query: 354 EFVTTSGRDNLKSLEGFIKES--GFFVGEKITLAELFFVVLTDYLEKLPK--LYDDFPKL 521
E + L + +K S VG+K+TLA+L + + D++ L K L +P++
Sbjct: 126 EILNGKVPVLLDIICESLKASTGKLAVGDKVTLADLVLIAVIDHVTDLDKEFLTGKYPEI 185
Query: 522 KELRERVLKANTDVEDWVKTRPVT 593
+ RE +L ++ + ++ R T
Sbjct: 186 HKHRENLLASSPRLAKYLSDRAAT 209
>sp|P30113|GST28_SCHBO Glutathione S-transferase 28 kDa (GST 28) (GST class-mu)
Length = 211
Score = 122 bits (305), Expect = 1e-27
Identities = 72/204 (35%), Positives = 116/204 (56%), Gaps = 9/204 (4%)
Frame = +3
Query: 9 VKVTYFNARGRAEIIRLVLKASKVEFEDVRLTKEQWVDVKPTTPTGKLPVVEYEG----- 173
+KV YFN RGRAE IR+ L A+ V +ED R++ + W +KPT P G+LP V+
Sbjct: 6 IKVIYFNGRGRAESIRMTLVAAGVNYEDERISFQDWPKIKPTIPGGRLPAVKITDNHGHV 65
Query: 174 KKLTQSMAIARAIARKYGFMGEDDKEYYLIERAIGQMVDVLEGMYKIYFAPEEKKEDLRT 353
K + +S+AIAR +A+K+ MG ++EYY +E+ IGQ D+ YK PEE+K+ +
Sbjct: 66 KWMVESLAIARYMAKKHHMMGGTEEEYYNVEKLIGQAEDLEHEYYKTLMKPEEEKQKIIK 125
Query: 354 EFVTTSGRDNLKSLEGFIKES--GFFVGEKITLAELFFVVLTDYLEKLPK--LYDDFPKL 521
E + L + +K S VG+K+TLA+L + + D++ L K L +P++
Sbjct: 126 EILNGKVPVLLDIICESLKASTGKLAVGDKVTLADLVLIAVIDHVTDLDKEFLTGKYPEI 185
Query: 522 KELRERVLKANTDVEDWVKTRPVT 593
+ RE +L ++ + ++ R T
Sbjct: 186 HKHRENLLASSPRLAKYLSDRAAT 209
>sp|O73888|PTGD2_CHICK Glutathione-requiring prostaglandin D synthase
(Glutathione-dependent PGD synthetase) (Prostaglandin-H2
D-isomerase) (Hematopoietic prostaglandin D synthase)
(H-PGDS)
Length = 199
Score = 116 bits (291), Expect = 4e-26
Identities = 69/199 (34%), Positives = 112/199 (56%), Gaps = 5/199 (2%)
Frame = +3
Query: 12 KVTYFNARGRAEIIRLVLKASKVEFEDVRLTKEQWVDVKPTTPTGKLPVVEYEGKKLTQS 191
K+TYFN RGRAEI R + + +++ED RL W +KPT P GK+P++E +G + QS
Sbjct: 5 KLTYFNLRGRAEICRYLFAYAGIKYEDHRLEGADWPKIKPTIPFGKVPILEVDGVIIHQS 64
Query: 192 MAIARAIARKYGFMGEDDKEYYLIERAIGQMVDVLEGMYKIYFAPEEKKEDLR----TEF 359
+AIAR +AR+ G G+ E L + + + D + + F EK +D++ +
Sbjct: 65 LAIARYLARESGLAGQTPVEQALADAIVDTIDD-----FMMLFPWAEKNQDVKEKAFNDI 119
Query: 360 VTTSGRDNLKSLEGFIKESGFFVGEKITLAELFF-VVLTDYLEKLPKLYDDFPKLKELRE 536
+T + LK L+ F+ + +FVG+ +T A+ ++ V T L L D +P+L LR+
Sbjct: 120 LTNKAPELLKDLDTFLGDKKWFVGKSVTWADFYWDVCSTTLLSYKADLADKYPRLLALRD 179
Query: 537 RVLKANTDVEDWVKTRPVT 593
RV +A + W++ RP T
Sbjct: 180 RV-EALPAIAAWIQKRPKT 197
>sp|P91253|GST7_CAEEL Probable glutathione S-transferase 7 (GST class-sigma)
Length = 206
Score = 113 bits (282), Expect = 5e-25
Identities = 74/202 (36%), Positives = 110/202 (54%), Gaps = 8/202 (3%)
Frame = +3
Query: 12 KVTYFNARGRAEIIRLVLKASKVEFEDVRLTKEQWVDVKPTTPTGKLPVVEYEGKKLTQS 191
KV+YF RG EI R +L + +FED R+ KE+W VKP+TP G+LP++E +GK L QS
Sbjct: 5 KVSYFPIRGAGEIARQILAYAGQDFEDNRIPKEEWPAVKPSTPFGQLPLLEVDGKVLAQS 64
Query: 192 MAIARAIARKYGFMGEDDKEYYLIERAIGQMVDVLEG-----MYKIYFAPEEKKEDLRTE 356
AIAR +AR++G G+ E + Q D L M K+ FA E + L +
Sbjct: 65 HAIARYLARQFGINGKCAWEEAQVNSVADQFKDYLNEVRPYFMVKMGFA-EGDLDALAKD 123
Query: 357 FVTTSGRDNLKSLEGFIKE--SGFFVGEKITLAELFFVVLT-DYLEKLPKLYDDFPKLKE 527
+ + F+K SG+ VG+ +T +L T D L L D+FP+ K
Sbjct: 124 VFLPGFKKHYGFFANFLKSAGSGYLVGDSLTFVDLLVAQHTADLLAANAALLDEFPQFKA 183
Query: 528 LRERVLKANTDVEDWVKTRPVT 593
+E+V +N +++ W++TRPVT
Sbjct: 184 HQEKV-HSNANIKKWLETRPVT 204
>sp|P46088|GST_OMMSL Glutathione S-transferase (GST class-sigma)
Length = 203
Score = 112 bits (279), Expect = 1e-24
Identities = 71/197 (36%), Positives = 108/197 (54%), Gaps = 5/197 (2%)
Frame = +3
Query: 21 YFNARGRAEIIRLVLKASKVEFEDVRLTKEQWVDVKPTTPTGKLPVVEYEGKKLTQSMAI 200
YF GRAE+ R VL A EF D + W ++K T + +PV++ +G K++QSM I
Sbjct: 8 YFPLMGRAELCRFVLAAHGEEFTDRVVEMADWPNLKATMYSNAMPVLDIDGTKMSQSMCI 67
Query: 201 ARAIARKYGFMGEDDKEYYLIERAIGQMVDVLEGMYKIYFAPEEKKEDLRTEFVTTSGRD 380
AR +AR++G G+ E Y ++ + D+ + KI FAPE KE ++ + + R
Sbjct: 68 ARHLAREFGLDGKTSLEKYRVDEITETLQDIFNDVVKIKFAPEAAKEAVQQNYEKSCKR- 126
Query: 381 NLKSLEGFIKES----GFFVGEKITLAELF-FVVLTDYLEKLPKLYDDFPKLKELRERVL 545
LEG + + GFFVG +TLA+L +V L L+ P+L D PK+ LR+RV
Sbjct: 127 LAPFLEGLLVSNGGGDGFFVGNSMTLADLHCYVALEVPLKHTPELLKDCPKIVALRKRVA 186
Query: 546 KANTDVEDWVKTRPVTD 596
+ + ++K RPV D
Sbjct: 187 EC-PKIAAYLKKRPVRD 202
>sp|O16116|GST3_CAEEL Glutathione S-transferase 3 (GST class-sigma) (CeGST3)
Length = 207
Score = 110 bits (274), Expect = 4e-24
Identities = 70/205 (34%), Positives = 119/205 (58%), Gaps = 11/205 (5%)
Frame = +3
Query: 12 KVTYFNARGRAEIIRLVLKASKVEFEDVRLTKEQWVDVKPTTPTGKLPVVEYEGKKLTQS 191
K+TYFNARG AEI R + + VEFED R+ +E++ +KPT P+G++P++ +G + +QS
Sbjct: 5 KLTYFNARGLAEISRQLFHMAGVEFEDERINEEKFSQLKPTFPSGQVPILCIDGAQFSQS 64
Query: 192 MAIARAIARKYGFMGEDDKEYYLIERAIGQMVDVLEGMYKIYFA-----PEEKKEDLRTE 356
AIAR +ARK+GF+G+ +E + + D +E K A EE +++R E
Sbjct: 65 TAIARYLARKFGFVGQTAEEELQADEVVDTFKDFIESFRKFVIAVLSGESEEILKNIREE 124
Query: 357 FVTTSGRDNLKSLEGFIKE--SGFFVGEKITLAELFFVVLTDYLEKL--PKLYD--DFPK 518
+ + + L+ +++ SG+ VG ++T A+L V+ D L L +L D +
Sbjct: 125 VIKPAVKTYTAYLKAILEKSSSGYLVGNELTWADL---VIADNLTTLINAELLDIENDKL 181
Query: 519 LKELRERVLKANTDVEDWVKTRPVT 593
LKE RE++++ +++W+ RP T
Sbjct: 182 LKEFREKIIE-TPKLKEWLAKRPET 205
>sp|O60760|PTGD2_HUMAN Glutathione-requiring prostaglandin D synthase
(Glutathione-dependent PGD synthetase) (Prostaglandin-H2
D-isomerase) (Hematopoietic prostaglandin D synthase)
(H-PGDS)
Length = 199
Score = 108 bits (271), Expect = 9e-24
Identities = 64/200 (32%), Positives = 110/200 (55%), Gaps = 4/200 (2%)
Frame = +3
Query: 12 KVTYFNARGRAEIIRLVLKASKVEFEDVRLTKEQWVDVKPTTPTGKLPVVEYEGKKLTQS 191
K+TYFN RGRAEIIR + +++ED R+ + W ++K T P GK+P++E +G L QS
Sbjct: 5 KLTYFNMRGRAEIIRYIFAYLDIQYEDHRIEQADWPEIKSTLPFGKIPILEVDGLTLHQS 64
Query: 192 MAIARAIARKYGFMGEDDKEYYLIERAIGQMVDVLEGMYKIYFAPEEK---KEDLRTEFV 362
+AIAR + + G + E + + +VD L+ + E+K KE + E +
Sbjct: 65 LAIARYLTKNTDLAGNTEME----QCHVDAIVDTLDDFMSCFPWAEKKQDVKEQMFNELL 120
Query: 363 TTSGRDNLKSLEGFIKESGFFVGEKITLAELFF-VVLTDYLEKLPKLYDDFPKLKELRER 539
T + ++ L+ ++ + +G +T A+ ++ + T L P L D+ P+L LR++
Sbjct: 121 TYNAPHLMQDLDTYLGGREWLIGNSVTWADFYWEICSTTLLVFKPDLLDNHPRLVTLRKK 180
Query: 540 VLKANTDVEDWVKTRPVTDM 599
V +A V +W+K RP T +
Sbjct: 181 V-QAIPAVANWIKRRPQTKL 199
>sp|Q9JHF7|PTGD2_MOUSE Glutathione-requiring prostaglandin D synthase
(Glutathione-dependent PGD synthetase) (Prostaglandin-H2
D-isomerase) (Hematopoietic prostaglandin D synthase)
(H-PGDS)
Length = 199
Score = 107 bits (268), Expect = 2e-23
Identities = 63/197 (31%), Positives = 105/197 (53%), Gaps = 1/197 (0%)
Frame = +3
Query: 12 KVTYFNARGRAEIIRLVLKASKVEFEDVRLTKEQWVDVKPTTPTGKLPVVEYEGKKLTQS 191
K+ YFN RGRAEIIR + +++ED R+ + W +KPT P GK+PV+E EG + QS
Sbjct: 5 KLLYFNMRGRAEIIRYIFAYLDIKYEDHRIEQADWPKIKPTLPFGKIPVLEVEGLTIHQS 64
Query: 192 MAIARAIARKYGFMGEDDKEYYLIERAIGQMVDVLEGMYKIYFAPEEKKEDLRTEFVTTS 371
+AIAR + + G+ E + + + D + ++ ++ KE + E +T
Sbjct: 65 LAIARYLTKNTDLAGKTALEQCQADAVVDTLDDFM-SLFPWAEKDQDLKERMFNELLTHQ 123
Query: 372 GRDNLKSLEGFIKESGFFVGEKITLAELFF-VVLTDYLEKLPKLYDDFPKLKELRERVLK 548
LK L+ ++ + +F+G +T A+ ++ + T L P L D +PKL LR +V +
Sbjct: 124 APRLLKDLDTYLGDKEWFIGNYVTWADFYWDICSTTLLVLKPGLLDIYPKLVSLRNKV-Q 182
Query: 549 ANTDVEDWVKTRPVTDM 599
A + W+ RP T +
Sbjct: 183 AIPAISAWILKRPQTKL 199
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 72,485,866
Number of Sequences: 369166
Number of extensions: 1496185
Number of successful extensions: 5181
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4937
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5088
length of database: 68,354,980
effective HSP length: 106
effective length of database: 48,773,070
effective search space used: 5365037700
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)