Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_020_M08
(643 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P26624|GST28_SCHJA Glutathione S-transferase 28 kDa (GST... 132 6e-31
sp|P09792|GST28_SCHMA Glutathione S-transferase 28 kDa (GST... 125 7e-29
sp|P30114|GST28_SCHHA Glutathione S-transferase 28 kDa (GST... 122 8e-28
sp|P30113|GST28_SCHBO Glutathione S-transferase 28 kDa (GST... 119 9e-27
sp|O73888|PTGD2_CHICK Glutathione-requiring prostaglandin D... 114 2e-25
sp|P46088|GST_OMMSL Glutathione S-transferase (GST class-si... 112 1e-24
sp|P91253|GST7_CAEEL Probable glutathione S-transferase 7 (... 111 2e-24
sp|O16116|GST3_CAEEL Glutathione S-transferase 3 (GST class... 108 2e-23
sp|O60760|PTGD2_HUMAN Glutathione-requiring prostaglandin D... 107 3e-23
sp|Q9JHF7|PTGD2_MOUSE Glutathione-requiring prostaglandin D... 105 8e-23
>sp|P26624|GST28_SCHJA Glutathione S-transferase 28 kDa (GST 28) (SJ28 antigen) (GST
class-mu)
Length = 206
Score = 132 bits (333), Expect = 6e-31
Identities = 75/200 (37%), Positives = 119/200 (59%), Gaps = 9/200 (4%)
Frame = +1
Query: 7 YFNARGRAEIIRLVLKASKVEFEDVRLTKEQWVDVKPTTPTGKLPVVEYEGKK-----LT 171
YFN RGRAE IR++L A+ VEFED R+ + W +KPT P G+LP+V+ K+ ++
Sbjct: 5 YFNGRGRAEPIRMILVAAGVEFEDERIEFQDWPKIKPTIPGGRLPIVKITDKRGDVKTMS 64
Query: 172 QSMAIARAIARKYGFMGEDDKEYYLIERAIGQMVDVLEGMYKIYFAPEEKKEDLRTEFVT 351
+S+AIAR IARK+ MG+ D EYY+IE+ IGQ+ DV +K P E+KE + E +
Sbjct: 65 ESLAIARFIARKHNMMGDTDDEYYIIEKMIGQVEDVESEYHKTLIKPPEEKEKISKEILN 124
Query: 352 TSGRDNLKSLEGFIKES--GFFVGEKITLAELFFVVLTDYLEKLPK--LYDDFPKLKELR 519
L+++ +KES VG+K+TLA++ + D++ L K L +P++ + R
Sbjct: 125 GKVPILLQAICETLKESTGNLTVGDKVTLADVVLIASIDHITDLDKEFLTGKYPEIHKHR 184
Query: 520 ERVLKANTDVEDWVKTRPVT 579
+ +L + + ++ R T
Sbjct: 185 KHLLATSPKLAKYLSERHAT 204
>sp|P09792|GST28_SCHMA Glutathione S-transferase 28 kDa (GST 28) (SM28 antigen)
(Protective 28 kDa antigen) (GST class-mu)
Length = 211
Score = 125 bits (315), Expect = 7e-29
Identities = 73/202 (36%), Positives = 117/202 (57%), Gaps = 9/202 (4%)
Frame = +1
Query: 1 VTYFNARGRAEIIRLVLKASKVEFEDVRLTKEQWVDVKPTTPTGKLPVVEYEG-----KK 165
V YF+ RGRAE IR+ L A+ V++ED R++ + W +KPT P G+LP V+ K
Sbjct: 8 VIYFDGRGRAESIRMTLVAAGVDYEDERISFQDWPKIKPTIPGGRLPAVKVTDDHGHVKW 67
Query: 166 LTQSMAIARAIARKYGFMGEDDKEYYLIERAIGQMVDVLEGMYKIYFAPEEKKEDLRTEF 345
+ +S+AIAR +A+K+ MGE D+EYY +E+ IGQ DV +K P+E+KE + E
Sbjct: 68 MLESLAIARYMAKKHHMMGETDEEYYSVEKLIGQAEDVEHEYHKTLMKPQEEKEKITKEI 127
Query: 346 VTTSGRDNLKSLEGFIKES--GFFVGEKITLAELFFVVLTDYLEKLPK--LYDDFPKLKE 513
+ L + +K S VG+K+TLA+L + + D++ L K L +P++ +
Sbjct: 128 LNGKVPVLLNMICESLKGSTGKLAVGDKVTLADLVLIAVIDHVTDLDKGFLTGKYPEIHK 187
Query: 514 LRERVLKANTDVEDWVKTRPVT 579
RE +L ++ + ++ RP T
Sbjct: 188 HRENLLASSPRLAKYLSNRPAT 209
>sp|P30114|GST28_SCHHA Glutathione S-transferase 28 kDa (GST 28) (GST class-mu)
Length = 211
Score = 122 bits (306), Expect = 8e-28
Identities = 72/202 (35%), Positives = 116/202 (57%), Gaps = 9/202 (4%)
Frame = +1
Query: 1 VTYFNARGRAEIIRLVLKASKVEFEDVRLTKEQWVDVKPTTPTGKLPVVEYEG-----KK 165
V YFN RGRAE IR+ L A+ V +ED R++ + W +KPT P G+LP V+ K
Sbjct: 8 VIYFNGRGRAESIRMTLVAAGVNYEDERISFQDWPKIKPTIPGGRLPAVKITDNHGHVKW 67
Query: 166 LTQSMAIARAIARKYGFMGEDDKEYYLIERAIGQMVDVLEGMYKIYFAPEEKKEDLRTEF 345
+ +S+AIAR +A+K+ MGE D+EYY +E+ IGQ+ D+ +K PEE+K+ + E
Sbjct: 68 MLESLAIARYMAKKHHMMGETDEEYYNVEKLIGQVEDLEHEYHKTLMKPEEEKQKITKEI 127
Query: 346 VTTSGRDNLKSLEGFIKES--GFFVGEKITLAELFFVVLTDYLEKLPK--LYDDFPKLKE 513
+ L + +K S VG+K+TLA+L + + D++ L K L +P++ +
Sbjct: 128 LNGKVPVLLDIICESLKASTGKLAVGDKVTLADLVLIAVIDHVTDLDKEFLTGKYPEIHK 187
Query: 514 LRERVLKANTDVEDWVKTRPVT 579
RE +L ++ + ++ R T
Sbjct: 188 HRENLLASSPRLAKYLSDRAAT 209
>sp|P30113|GST28_SCHBO Glutathione S-transferase 28 kDa (GST 28) (GST class-mu)
Length = 211
Score = 119 bits (297), Expect = 9e-27
Identities = 71/202 (35%), Positives = 114/202 (56%), Gaps = 9/202 (4%)
Frame = +1
Query: 1 VTYFNARGRAEIIRLVLKASKVEFEDVRLTKEQWVDVKPTTPTGKLPVVEYEG-----KK 165
V YFN RGRAE IR+ L A+ V +ED R++ + W +KPT P G+LP V+ K
Sbjct: 8 VIYFNGRGRAESIRMTLVAAGVNYEDERISFQDWPKIKPTIPGGRLPAVKITDNHGHVKW 67
Query: 166 LTQSMAIARAIARKYGFMGEDDKEYYLIERAIGQMVDVLEGMYKIYFAPEEKKEDLRTEF 345
+ +S+AIAR +A+K+ MG ++EYY +E+ IGQ D+ YK PEE+K+ + E
Sbjct: 68 MVESLAIARYMAKKHHMMGGTEEEYYNVEKLIGQAEDLEHEYYKTLMKPEEEKQKIIKEI 127
Query: 346 VTTSGRDNLKSLEGFIKES--GFFVGEKITLAELFFVVLTDYLEKLPK--LYDDFPKLKE 513
+ L + +K S VG+K+TLA+L + + D++ L K L +P++ +
Sbjct: 128 LNGKVPVLLDIICESLKASTGKLAVGDKVTLADLVLIAVIDHVTDLDKEFLTGKYPEIHK 187
Query: 514 LRERVLKANTDVEDWVKTRPVT 579
RE +L ++ + ++ R T
Sbjct: 188 HRENLLASSPRLAKYLSDRAAT 209
>sp|O73888|PTGD2_CHICK Glutathione-requiring prostaglandin D synthase
(Glutathione-dependent PGD synthetase) (Prostaglandin-H2
D-isomerase) (Hematopoietic prostaglandin D synthase)
(H-PGDS)
Length = 199
Score = 114 bits (286), Expect = 2e-25
Identities = 68/198 (34%), Positives = 111/198 (56%), Gaps = 5/198 (2%)
Frame = +1
Query: 1 VTYFNARGRAEIIRLVLKASKVEFEDVRLTKEQWVDVKPTTPTGKLPVVEYEGKKLTQSM 180
+TYFN RGRAEI R + + +++ED RL W +KPT P GK+P++E +G + QS+
Sbjct: 6 LTYFNLRGRAEICRYLFAYAGIKYEDHRLEGADWPKIKPTIPFGKVPILEVDGVIIHQSL 65
Query: 181 AIARAIARKYGFMGEDDKEYYLIERAIGQMVDVLEGMYKIYFAPEEKKEDLR----TEFV 348
AIAR +AR+ G G+ E L + + + D + + F EK +D++ + +
Sbjct: 66 AIARYLARESGLAGQTPVEQALADAIVDTIDD-----FMMLFPWAEKNQDVKEKAFNDIL 120
Query: 349 TTSGRDNLKSLEGFIKESGFFVGEKITLAELFF-VVLTDYLEKLPKLYDDFPKLKELRER 525
T + LK L+ F+ + +FVG+ +T A+ ++ V T L L D +P+L LR+R
Sbjct: 121 TNKAPELLKDLDTFLGDKKWFVGKSVTWADFYWDVCSTTLLSYKADLADKYPRLLALRDR 180
Query: 526 VLKANTDVEDWVKTRPVT 579
V +A + W++ RP T
Sbjct: 181 V-EALPAIAAWIQKRPKT 197
>sp|P46088|GST_OMMSL Glutathione S-transferase (GST class-sigma)
Length = 203
Score = 112 bits (279), Expect = 1e-24
Identities = 71/197 (36%), Positives = 108/197 (54%), Gaps = 5/197 (2%)
Frame = +1
Query: 7 YFNARGRAEIIRLVLKASKVEFEDVRLTKEQWVDVKPTTPTGKLPVVEYEGKKLTQSMAI 186
YF GRAE+ R VL A EF D + W ++K T + +PV++ +G K++QSM I
Sbjct: 8 YFPLMGRAELCRFVLAAHGEEFTDRVVEMADWPNLKATMYSNAMPVLDIDGTKMSQSMCI 67
Query: 187 ARAIARKYGFMGEDDKEYYLIERAIGQMVDVLEGMYKIYFAPEEKKEDLRTEFVTTSGRD 366
AR +AR++G G+ E Y ++ + D+ + KI FAPE KE ++ + + R
Sbjct: 68 ARHLAREFGLDGKTSLEKYRVDEITETLQDIFNDVVKIKFAPEAAKEAVQQNYEKSCKR- 126
Query: 367 NLKSLEGFIKES----GFFVGEKITLAELF-FVVLTDYLEKLPKLYDDFPKLKELRERVL 531
LEG + + GFFVG +TLA+L +V L L+ P+L D PK+ LR+RV
Sbjct: 127 LAPFLEGLLVSNGGGDGFFVGNSMTLADLHCYVALEVPLKHTPELLKDCPKIVALRKRVA 186
Query: 532 KANTDVEDWVKTRPVTD 582
+ + ++K RPV D
Sbjct: 187 EC-PKIAAYLKKRPVRD 202
>sp|P91253|GST7_CAEEL Probable glutathione S-transferase 7 (GST class-sigma)
Length = 206
Score = 111 bits (277), Expect = 2e-24
Identities = 73/201 (36%), Positives = 109/201 (54%), Gaps = 8/201 (3%)
Frame = +1
Query: 1 VTYFNARGRAEIIRLVLKASKVEFEDVRLTKEQWVDVKPTTPTGKLPVVEYEGKKLTQSM 180
V+YF RG EI R +L + +FED R+ KE+W VKP+TP G+LP++E +GK L QS
Sbjct: 6 VSYFPIRGAGEIARQILAYAGQDFEDNRIPKEEWPAVKPSTPFGQLPLLEVDGKVLAQSH 65
Query: 181 AIARAIARKYGFMGEDDKEYYLIERAIGQMVDVLEG-----MYKIYFAPEEKKEDLRTEF 345
AIAR +AR++G G+ E + Q D L M K+ FA E + L +
Sbjct: 66 AIARYLARQFGINGKCAWEEAQVNSVADQFKDYLNEVRPYFMVKMGFA-EGDLDALAKDV 124
Query: 346 VTTSGRDNLKSLEGFIKE--SGFFVGEKITLAELFFVVLT-DYLEKLPKLYDDFPKLKEL 516
+ + F+K SG+ VG+ +T +L T D L L D+FP+ K
Sbjct: 125 FLPGFKKHYGFFANFLKSAGSGYLVGDSLTFVDLLVAQHTADLLAANAALLDEFPQFKAH 184
Query: 517 RERVLKANTDVEDWVKTRPVT 579
+E+V +N +++ W++TRPVT
Sbjct: 185 QEKV-HSNANIKKWLETRPVT 204
>sp|O16116|GST3_CAEEL Glutathione S-transferase 3 (GST class-sigma) (CeGST3)
Length = 207
Score = 108 bits (269), Expect = 2e-23
Identities = 69/204 (33%), Positives = 118/204 (57%), Gaps = 11/204 (5%)
Frame = +1
Query: 1 VTYFNARGRAEIIRLVLKASKVEFEDVRLTKEQWVDVKPTTPTGKLPVVEYEGKKLTQSM 180
+TYFNARG AEI R + + VEFED R+ +E++ +KPT P+G++P++ +G + +QS
Sbjct: 6 LTYFNARGLAEISRQLFHMAGVEFEDERINEEKFSQLKPTFPSGQVPILCIDGAQFSQST 65
Query: 181 AIARAIARKYGFMGEDDKEYYLIERAIGQMVDVLEGMYKIYFA-----PEEKKEDLRTEF 345
AIAR +ARK+GF+G+ +E + + D +E K A EE +++R E
Sbjct: 66 AIARYLARKFGFVGQTAEEELQADEVVDTFKDFIESFRKFVIAVLSGESEEILKNIREEV 125
Query: 346 VTTSGRDNLKSLEGFIKE--SGFFVGEKITLAELFFVVLTDYLEKL--PKLYD--DFPKL 507
+ + + L+ +++ SG+ VG ++T A+L V+ D L L +L D + L
Sbjct: 126 IKPAVKTYTAYLKAILEKSSSGYLVGNELTWADL---VIADNLTTLINAELLDIENDKLL 182
Query: 508 KELRERVLKANTDVEDWVKTRPVT 579
KE RE++++ +++W+ RP T
Sbjct: 183 KEFREKIIE-TPKLKEWLAKRPET 205
>sp|O60760|PTGD2_HUMAN Glutathione-requiring prostaglandin D synthase
(Glutathione-dependent PGD synthetase) (Prostaglandin-H2
D-isomerase) (Hematopoietic prostaglandin D synthase)
(H-PGDS)
Length = 199
Score = 107 bits (266), Expect = 3e-23
Identities = 63/199 (31%), Positives = 109/199 (54%), Gaps = 4/199 (2%)
Frame = +1
Query: 1 VTYFNARGRAEIIRLVLKASKVEFEDVRLTKEQWVDVKPTTPTGKLPVVEYEGKKLTQSM 180
+TYFN RGRAEIIR + +++ED R+ + W ++K T P GK+P++E +G L QS+
Sbjct: 6 LTYFNMRGRAEIIRYIFAYLDIQYEDHRIEQADWPEIKSTLPFGKIPILEVDGLTLHQSL 65
Query: 181 AIARAIARKYGFMGEDDKEYYLIERAIGQMVDVLEGMYKIYFAPEEK---KEDLRTEFVT 351
AIAR + + G + E + + +VD L+ + E+K KE + E +T
Sbjct: 66 AIARYLTKNTDLAGNTEME----QCHVDAIVDTLDDFMSCFPWAEKKQDVKEQMFNELLT 121
Query: 352 TSGRDNLKSLEGFIKESGFFVGEKITLAELFF-VVLTDYLEKLPKLYDDFPKLKELRERV 528
+ ++ L+ ++ + +G +T A+ ++ + T L P L D+ P+L LR++V
Sbjct: 122 YNAPHLMQDLDTYLGGREWLIGNSVTWADFYWEICSTTLLVFKPDLLDNHPRLVTLRKKV 181
Query: 529 LKANTDVEDWVKTRPVTDM 585
+A V +W+K RP T +
Sbjct: 182 -QAIPAVANWIKRRPQTKL 199
>sp|Q9JHF7|PTGD2_MOUSE Glutathione-requiring prostaglandin D synthase
(Glutathione-dependent PGD synthetase) (Prostaglandin-H2
D-isomerase) (Hematopoietic prostaglandin D synthase)
(H-PGDS)
Length = 199
Score = 105 bits (263), Expect = 8e-23
Identities = 62/194 (31%), Positives = 103/194 (53%), Gaps = 1/194 (0%)
Frame = +1
Query: 7 YFNARGRAEIIRLVLKASKVEFEDVRLTKEQWVDVKPTTPTGKLPVVEYEGKKLTQSMAI 186
YFN RGRAEIIR + +++ED R+ + W +KPT P GK+PV+E EG + QS+AI
Sbjct: 8 YFNMRGRAEIIRYIFAYLDIKYEDHRIEQADWPKIKPTLPFGKIPVLEVEGLTIHQSLAI 67
Query: 187 ARAIARKYGFMGEDDKEYYLIERAIGQMVDVLEGMYKIYFAPEEKKEDLRTEFVTTSGRD 366
AR + + G+ E + + + D + ++ ++ KE + E +T
Sbjct: 68 ARYLTKNTDLAGKTALEQCQADAVVDTLDDFM-SLFPWAEKDQDLKERMFNELLTHQAPR 126
Query: 367 NLKSLEGFIKESGFFVGEKITLAELFF-VVLTDYLEKLPKLYDDFPKLKELRERVLKANT 543
LK L+ ++ + +F+G +T A+ ++ + T L P L D +PKL LR +V +A
Sbjct: 127 LLKDLDTYLGDKEWFIGNYVTWADFYWDICSTTLLVLKPGLLDIYPKLVSLRNKV-QAIP 185
Query: 544 DVEDWVKTRPVTDM 585
+ W+ RP T +
Sbjct: 186 AISAWILKRPQTKL 199
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 71,482,417
Number of Sequences: 369166
Number of extensions: 1481248
Number of successful extensions: 5140
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4896
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5049
length of database: 68,354,980
effective HSP length: 106
effective length of database: 48,773,070
effective search space used: 5218718490
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)