Planaria EST Database

DrC_00748

BLASTX 2.2.13 [Nov-27-2005]

Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= DrC_00748
         (1460 letters)

Database: Non-redundant SwissProt sequences 
           184,735 sequences; 68,354,980 total letters



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

sp|Q11067|PDIA6_CAEEL  Probable protein disulfide-isomerase ...   491   e-138
sp|Q63081|PDIA6_RAT  Protein disulfide-isomerase A6 precurso...   483   e-136
sp|Q922R8|PDIA6_MOUSE  Protein disulfide-isomerase A6 precur...   482   e-135
sp|Q15084|PDIA6_HUMAN  Protein disulfide-isomerase A6 precur...   480   e-135
sp|Q5R6T1|PDIA6_PONPY  Protein disulfide-isomerase A6 precursor   477   e-134
sp|P38660|PDIA6_MESAU  Protein disulfide-isomerase A6 precur...   471   e-132
sp|O22263|PDIA6_ARATH  Probable protein disulfide-isomerase ...   177   9e-44
sp|P34329|PDIA4_CAEEL  Probable protein disulfide-isomerase ...   163   1e-39
sp|Q92249|ERP38_NEUCR  Protein disulfide-isomerase erp38 pre...   154   5e-37
sp|Q00216|TIGA_ASPNG  Protein disulfide-isomerase tigA precu...   145   3e-34

>sp|Q11067|PDIA6_CAEEL Probable protein disulfide-isomerase A6 precursor
          Length = 440

 Score =  491 bits (1265), Expect = e-138
 Identities = 227/424 (53%), Positives = 304/424 (71%), Gaps = 2/424 (0%)
 Frame = +3

Query: 69   LYSPSDDVIDLTPSNFND-VKNGDELWFVEFYAPWCGHCQSLAPEWKKAASALKGVVKVG 245
            +YS  DDV++LT +NF   V N D++W VEFYAPWCGHC+SL PE+KKAASALKGV KVG
Sbjct: 19   MYSKKDDVVELTEANFQSKVINSDDIWIVEFYAPWCGHCKSLVPEYKKAASALKGVAKVG 78

Query: 246  AVDMDKYSSVGQPYNIQGFPTIKVFGKNKHSPKDYQGERNANAIVNNALKELEELVRSRL 425
            AVDM ++ SVG PYN+QGFPT+K+FG +K  P DY G+R A AI ++ L E ++ V +RL
Sbjct: 79   AVDMTQHQSVGGPYNVQGFPTLKIFGADKKKPTDYNGQRTAQAIADSVLAEAKKAVSARL 138

Query: 426  XXXXXXXXXXXXXXXXXXXXXXXXX-EVIELTDSNFDELVLKSEEPWLVEFFAPWCGHCK 602
                                      EV+ELTD+NF++LVL S++ WLVEFFAPWCGHCK
Sbjct: 139  GGKSSGSSSSGSGSGSGKRGGGGSGNEVVELTDANFEDLVLNSKDIWLVEFFAPWCGHCK 198

Query: 603  NLKPHWDQAASELRGKVKLGALDATVHNAVASRYGVQGYPTIKFFPAGVKTGEAQEYDGG 782
            +L+P W  AASEL+GKV+LGALDATVH  VA+++ ++G+PTIK+F  G    +AQ+YDGG
Sbjct: 199  SLEPQWKAAASELKGKVRLGALDATVHTVVANKFAIRGFPTIKYFAPGSDVSDAQDYDGG 258

Query: 783  RSSSDIVRWASDKVVEQLPAPELKEITNQDVLKSTCEDHQLCVIAVLPNILDCQSACRNS 962
            R SSDIV WAS +  E +PAPE+ E  NQ V++  C++ QLC+ A LP+ILDCQS CRN+
Sbjct: 259  RQSSDIVAWASARAQENMPAPEVFEGINQQVVEDACKEKQLCIFAFLPHILDCQSECRNN 318

Query: 963  YLDTIRVSSDKYKANRWGWCWTEAMKLPAIEKAFGIGGFGYPALVVVNVRKMKYATLTGP 1142
            YL  ++  S+K+K N WGW W E    PA+E++F +GGFGYPA+  +N RK KYA L G 
Sbjct: 319  YLAMLKEQSEKFKKNLWGWIWVEGAAQPALEESFEVGGFGYPAMTALNFRKNKYAVLKGS 378

Query: 1143 FSQTGIQDFVRDVSLGRGSTAAIVGEGLPAITPVDPWDGKDGEMPKEEEIDLSELGIEEP 1322
            F + GI +F+RD+S G+G T+++ G+G P I   + WDGKDG +P E++IDLS++ ++  
Sbjct: 379  FGKDGIHEFLRDLSYGKGRTSSLRGDGFPKIQKTEKWDGKDGALPAEDDIDLSDIDLD-- 436

Query: 1323 KSEL 1334
            K+EL
Sbjct: 437  KTEL 440

>sp|Q63081|PDIA6_RAT Protein disulfide-isomerase A6 precursor (Protein disulfide isomerase
            P5) (Calcium-binding protein 1) (CaBP1) (Thioredoxin
            domain-containing protein 7)
          Length = 440

 Score =  483 bits (1244), Expect = e-136
 Identities = 240/429 (55%), Positives = 299/429 (69%), Gaps = 6/429 (1%)
 Frame = +3

Query: 66   ALYSPSDDVIDLTPSNFN-DVKNGDELWFVEFYAPWCGHCQSLAPEWKKAASALKGVVKV 242
            ALYS SDDVI+LTPSNFN +V   D LW VEFYAPWCGHCQ L PEWKKAASALK VVKV
Sbjct: 19   ALYSSSDDVIELTPSNFNREVIQSDSLWLVEFYAPWCGHCQRLTPEWKKAASALKDVVKV 78

Query: 243  GAVDMDKYSSVGQPYNIQGFPTIKVFGKNKHSPKDYQGERNANAIVNNALKELEELVRSR 422
            GAV+ DK+ S+G  Y +QGFPTIK+FG NK+ P+DYQG R   AIV+ AL  L +LV+ R
Sbjct: 79   GAVNADKHQSLGGQYGVQGFPTIKIFGANKNKPEDYQGGRTGEAIVDAALSALRQLVKDR 138

Query: 423  LXXXXXXXXXXXXXXXXXXXXXXXXXEVIELTDSNFDELVLKSEEPWLVEFFAPWCGHCK 602
            L                         +V+ELTD  FD+ VL SE+ W+VEF+APWCGHCK
Sbjct: 139  LGGRSGGYSSGKQGRGDSSSKK----DVVELTDDTFDKNVLDSEDVWMVEFYAPWCGHCK 194

Query: 603  NLKPHWDQAASELR----GKVKLGALDATVHNAVASRYGVQGYPTIKFFPAGVKTGEAQE 770
            NL+P W  AA+E++    GKVKL A+DATV+  +ASRYG++G+PTIK F  G       +
Sbjct: 195  NLEPEWAAAATEVKEQTKGKVKLAAVDATVNQVLASRYGIKGFPTIKIFQKGESP---VD 251

Query: 771  YDGGRSSSDIVRWASDKVVEQLPAPELKEITNQDVLKSTCEDHQLCVIAVLPNILDCQSA 950
            YDGGR+ SDIV  A D   +  P PEL EI N+D+ K TCE+HQLCV+AVLP+ILD  + 
Sbjct: 252  YDGGRTRSDIVSRALDLFSDNAPPPELLEIINEDIAKKTCEEHQLCVVAVLPHILDTGAT 311

Query: 951  CRNSYLDTIRVSSDKYKANRWGWCWTEAMKLPAIEKAFGIGGFGYPALVVVNVRKMKYAT 1130
             RNSYL+ +   +DKYK   WGW WTEA     +E A GIGGFGYPA+  +N RKMK+A 
Sbjct: 312  GRNSYLEVLLKLADKYKKKMWGWLWTEAGAQYELENALGIGGFGYPAMAAINARKMKFAL 371

Query: 1131 LTGPFSQTGIQDFVRDVSLGRGSTAAIVGEGLPAITPVDPWDGKDGEMPKEEEIDLSELG 1310
            L G FS+ GI +F+R++S GRGSTA + G   P ITP +PWDGKDGE+P E++IDLS++ 
Sbjct: 372  LKGSFSEQGINEFLRELSFGRGSTAPVGGGSFPNITprePWDGKDGELPVEDDIDLSDVE 431

Query: 1311 IEE-PKSEL 1334
            +++  K EL
Sbjct: 432  LDDLEKDEL 440

>sp|Q922R8|PDIA6_MOUSE Protein disulfide-isomerase A6 precursor (Thioredoxin
            domain-containing protein 7)
          Length = 440

 Score =  482 bits (1241), Expect = e-135
 Identities = 239/428 (55%), Positives = 299/428 (69%), Gaps = 6/428 (1%)
 Frame = +3

Query: 69   LYSPSDDVIDLTPSNFN-DVKNGDELWFVEFYAPWCGHCQSLAPEWKKAASALKGVVKVG 245
            LYS SDDVI+LTPSNFN +V   D LW VEFYAPWCGHCQ L PEWKKAA+ALK VVKVG
Sbjct: 20   LYSSSDDVIELTPSNFNREVIQSDGLWLVEFYAPWCGHCQRLTPEWKKAATALKDVVKVG 79

Query: 246  AVDMDKYSSVGQPYNIQGFPTIKVFGKNKHSPKDYQGERNANAIVNNALKELEELVRSRL 425
            AV+ DK+ S+G  Y +QGFPTIK+FG NK+ P+DYQG R   AIV+ AL  L +LV+ RL
Sbjct: 80   AVNADKHQSLGGQYGVQGFPTIKIFGANKNKPEDYQGGRTGEAIVDAALSALRQLVKDRL 139

Query: 426  XXXXXXXXXXXXXXXXXXXXXXXXXEVIELTDSNFDELVLKSEEPWLVEFFAPWCGHCKN 605
                                     +V+ELTD  FD+ VL SE+ W+VEF+APWCGHCKN
Sbjct: 140  GGRSGGYSSGKQGRGDSSSKK----DVVELTDDTFDKNVLDSEDVWMVEFYAPWCGHCKN 195

Query: 606  LKPHWDQAASELR----GKVKLGALDATVHNAVASRYGVQGYPTIKFFPAGVKTGEAQEY 773
            L+P W  AA+E++    GKVKL A+DATV+  +ASRYG++G+PTIK F  G       +Y
Sbjct: 196  LEPEWAAAATEVKEQTKGKVKLAAVDATVNQVLASRYGIKGFPTIKIFQKGESP---VDY 252

Query: 774  DGGRSSSDIVRWASDKVVEQLPAPELKEITNQDVLKSTCEDHQLCVIAVLPNILDCQSAC 953
            DGGR+ SDIV  A D   +  P PEL EI N+D+ K TCE+HQLCV+AVLP+ILD  +A 
Sbjct: 253  DGGRTRSDIVSRALDLFSDNAPPPELLEIINEDIAKKTCEEHQLCVVAVLPHILDTGAAG 312

Query: 954  RNSYLDTIRVSSDKYKANRWGWCWTEAMKLPAIEKAFGIGGFGYPALVVVNVRKMKYATL 1133
            RNSYL+ +   +DKYK   WGW WTEA     +E A GIGGFGYPA+  +N RKMK+A L
Sbjct: 313  RNSYLEVLLKLADKYKKKMWGWLWTEAGAQYELENALGIGGFGYPAMAAINARKMKFALL 372

Query: 1134 TGPFSQTGIQDFVRDVSLGRGSTAAIVGEGLPAITPVDPWDGKDGEMPKEEEIDLSELGI 1313
             G FS+ GI +F+R++S GRGSTA + G   P ITP +PWDGKDGE+P E++IDLS++ +
Sbjct: 373  KGSFSEQGINEFLRELSFGRGSTAPVGGGSFPTITprePWDGKDGELPVEDDIDLSDVEL 432

Query: 1314 EE-PKSEL 1334
            ++  K EL
Sbjct: 433  DDLEKDEL 440

>sp|Q15084|PDIA6_HUMAN Protein disulfide-isomerase A6 precursor (Protein disulfide isomerase
            P5) (Thioredoxin domain-containing protein 7)
          Length = 440

 Score =  480 bits (1235), Expect = e-135
 Identities = 236/422 (55%), Positives = 295/422 (69%), Gaps = 5/422 (1%)
 Frame = +3

Query: 69   LYSPSDDVIDLTPSNFN-DVKNGDELWFVEFYAPWCGHCQSLAPEWKKAASALKGVVKVG 245
            LYS SDDVI+LTPSNFN +V   D LW VEFYAPWCGHCQ L PEWKKAA+ALK VVKVG
Sbjct: 20   LYSSSDDVIELTPSNFNREVIQSDSLWLVEFYAPWCGHCQRLTPEWKKAATALKDVVKVG 79

Query: 246  AVDMDKYSSVGQPYNIQGFPTIKVFGKNKHSPKDYQGERNANAIVNNALKELEELVRSRL 425
            AVD DK+ S+G  Y +QGFPTIK+FG NK+ P+DYQG R   AIV+ AL  L +LV+ RL
Sbjct: 80   AVDADKHHSLGGQYGVQGFPTIKIFGSNKNRPEDYQGGRTGEAIVDAALSALRQLVKDRL 139

Query: 426  XXXXXXXXXXXXXXXXXXXXXXXXXEVIELTDSNFDELVLKSEEPWLVEFFAPWCGHCKN 605
                                     +VIELTD +FD+ VL SE+ W+VEF+APWCGHCKN
Sbjct: 140  GGRSGGYSSGKQGRSDSSSKK----DVIELTDDSFDKNVLDSEDVWMVEFYAPWCGHCKN 195

Query: 606  LKPHWDQAASELR----GKVKLGALDATVHNAVASRYGVQGYPTIKFFPAGVKTGEAQEY 773
            L+P W  AASE++    GKVKL A+DATV+  +ASRYG++G+PTIK F  G       +Y
Sbjct: 196  LEPEWAAAASEVKEQTKGKVKLAAVDATVNQVLASRYGIRGFPTIKIFQKGESP---VDY 252

Query: 774  DGGRSSSDIVRWASDKVVEQLPAPELKEITNQDVLKSTCEDHQLCVIAVLPNILDCQSAC 953
            DGGR+ SDIV  A D   +  P PEL EI N+D+ K TCE+HQLCV+AVLP+ILD  +A 
Sbjct: 253  DGGRTRSDIVSRALDLFSDNAPPPELLEIINEDIAKRTCEEHQLCVVAVLPHILDTGAAG 312

Query: 954  RNSYLDTIRVSSDKYKANRWGWCWTEAMKLPAIEKAFGIGGFGYPALVVVNVRKMKYATL 1133
            RNSYL+ +   +DKYK   WGW WTEA     +E A GIGGFGYPA+  +N RKMK+A L
Sbjct: 313  RNSYLEVLLKLADKYKKKMWGWLWTEAGAQSELETALGIGGFGYPAMAAINARKMKFALL 372

Query: 1134 TGPFSQTGIQDFVRDVSLGRGSTAAIVGEGLPAITPVDPWDGKDGEMPKEEEIDLSELGI 1313
             G FS+ GI +F+R++S GRGSTA + G   P I   +PWDG+DGE+P E++IDLS++ +
Sbjct: 373  KGSFSEQGINEFLRELSFGRGSTAPVGGGAFPTIVEREPWDGRDGELPVEDDIDLSDVEL 432

Query: 1314 EE 1319
            ++
Sbjct: 433  DD 434

>sp|Q5R6T1|PDIA6_PONPY Protein disulfide-isomerase A6 precursor
          Length = 440

 Score =  477 bits (1227), Expect = e-134
 Identities = 234/422 (55%), Positives = 295/422 (69%), Gaps = 5/422 (1%)
 Frame = +3

Query: 69   LYSPSDDVIDLTPSNFN-DVKNGDELWFVEFYAPWCGHCQSLAPEWKKAASALKGVVKVG 245
            LYS SDDVI+LTPSNFN +V   D LW VEFYAPWCGHCQ L PEWKKAA+ALK VVKVG
Sbjct: 20   LYSSSDDVIELTPSNFNREVIQSDSLWLVEFYAPWCGHCQRLTPEWKKAATALKDVVKVG 79

Query: 246  AVDMDKYSSVGQPYNIQGFPTIKVFGKNKHSPKDYQGERNANAIVNNALKELEELVRSRL 425
            AVD DK+ S+G  Y +QGFPTIK+FG NK+ P+DYQG R   AIV+ AL  L +LV+ RL
Sbjct: 80   AVDADKHHSLGGQYGVQGFPTIKIFGSNKNRPEDYQGGRTGEAIVDAALSALRQLVKDRL 139

Query: 426  XXXXXXXXXXXXXXXXXXXXXXXXXEVIELTDSNFDELVLKSEEPWLVEFFAPWCGHCKN 605
                                     +VIELTD +FD+ VL SE+ W+VEF+APWCGHCKN
Sbjct: 140  GGQSGGYSSGKQGRSDSSSKK----DVIELTDDSFDKNVLDSEDVWMVEFYAPWCGHCKN 195

Query: 606  LKPHWDQAASELR----GKVKLGALDATVHNAVASRYGVQGYPTIKFFPAGVKTGEAQEY 773
            L+P W  AASE++    GKVKL A+DATV+  +ASRYG++G+PTIK F  G       +Y
Sbjct: 196  LEPEWAAAASEVKEQTKGKVKLAAVDATVNQVLASRYGIRGFPTIKIFQKGESP---VDY 252

Query: 774  DGGRSSSDIVRWASDKVVEQLPAPELKEITNQDVLKSTCEDHQLCVIAVLPNILDCQSAC 953
            DGGR+ SDIV  A D   +  P PEL EI ++D+ K TCE+HQLCV++VLP+ILD  +A 
Sbjct: 253  DGGRTRSDIVSRALDLFSDNAPPPELLEIISEDIAKRTCEEHQLCVVSVLPHILDTGAAG 312

Query: 954  RNSYLDTIRVSSDKYKANRWGWCWTEAMKLPAIEKAFGIGGFGYPALVVVNVRKMKYATL 1133
            RNSYL+ +   +DKYK   WGW WTEA     +E A GIGGFGYPA+  +N RKMK+A L
Sbjct: 313  RNSYLEVLLKLADKYKKKMWGWLWTEAGAQSELETALGIGGFGYPAMAAINARKMKFALL 372

Query: 1134 TGPFSQTGIQDFVRDVSLGRGSTAAIVGEGLPAITPVDPWDGKDGEMPKEEEIDLSELGI 1313
             G FS+ GI +F+R++S GRGSTA + G   P I   +PWDG+DGE+P E++IDLS++ +
Sbjct: 373  KGSFSEQGINEFLRELSFGRGSTAPVGGGAFPTIVEREPWDGRDGELPVEDDIDLSDVEL 432

Query: 1314 EE 1319
            ++
Sbjct: 433  DD 434

>sp|P38660|PDIA6_MESAU Protein disulfide-isomerase A6 precursor (Protein disulfide isomerase
            P5)
          Length = 439

 Score =  471 bits (1212), Expect = e-132
 Identities = 238/429 (55%), Positives = 299/429 (69%), Gaps = 7/429 (1%)
 Frame = +3

Query: 69   LYSPSDDVIDLTPSNFN-DVKNGDELWFVEFYAPWCGHCQSLAPEWKKAASALKGVVKVG 245
            LYS SDDVI+LTPSNFN +V   + LW VEFYAPWCGHCQ L PEWKKAA+ALK VVKVG
Sbjct: 20   LYSSSDDVIELTPSNFNREVIQSNSLWLVEFYAPWCGHCQRLTPEWKKAATALKDVVKVG 79

Query: 246  AVDMDKYSSVGQPYNIQGFPTIKVFGKNKHSPKDYQGERNANAIVNNALKELEELVRSRL 425
            AVD DK+ S+G  Y +QGFPTIK+FG NK+ P+DYQG R   AIV+ AL  L +LV+ RL
Sbjct: 80   AVDADKHQSLGGQYGVQGFPTIKIFGANKNKPEDYQGGRTGEAIVDAALSALRQLVKDRL 139

Query: 426  XXXXXXXXXXXXXXXXXXXXXXXXXEVIELTDSNFDELVLKSEEPWLVEFFAPWCGHCKN 605
                                     +VIELTD  FD+ VL S++ W+VEF+APWCGHCKN
Sbjct: 140  SGRSGGYSSGKQGRGDSSSKK----DVIELTDDTFDKNVLDSDDVWMVEFYAPWCGHCKN 195

Query: 606  LKPHWDQAASELR----GKVKLGALDATVHNAVASRYGVQGYPTIKFFPAGVKTGEAQ-E 770
            L+P W  AA+E++    GKVKL A+DATV+  +A+RYG++G+PTIK F    + GEA  +
Sbjct: 196  LEPEWATAATEVKEQTKGKVKLAAVDATVNQVLANRYGIRGFPTIKIF----QKGEAPVD 251

Query: 771  YDGGRSSSDIVRWASDKVVEQLPAPELKEITNQDVLKSTCEDHQLCVIAVLPNILDCQSA 950
            YDGGR+ SDIV  A D   +  P PEL EI N+DV K  CE+HQLCV+AVLP+ILD   A
Sbjct: 252  YDGGRTRSDIVSRALDLFSDNAPPPELLEIINEDVAKKMCEEHQLCVVAVLPHILDT-GA 310

Query: 951  CRNSYLDTIRVSSDKYKANRWGWCWTEAMKLPAIEKAFGIGGFGYPALVVVNVRKMKYAT 1130
             RNSYL+ +   +DKYK   WGW WTEA     +E A GIGGFGYPA+  +N RKMK+A 
Sbjct: 311  ARNSYLEILLKLADKYKKKMWGWLWTEAGAQSELENALGIGGFGYPAMARINARKMKFAL 370

Query: 1131 LTGPFSQTGIQDFVRDVSLGRGSTAAIVGEGLPAITPVDPWDGKDGEMPKEEEIDLSELG 1310
            L G FS+ GI +F+R++S GR STA + G   PAIT  +PWDG+DGE+P E++IDLS++ 
Sbjct: 371  LKGSFSEQGINEFLRELSFGRASTAPVGGGSFPAITAREPWDGRDGELPVEDDIDLSDVE 430

Query: 1311 IEE-PKSEL 1334
            +++  K EL
Sbjct: 431  LDDLEKDEL 439

>sp|O22263|PDIA6_ARATH Probable protein disulfide-isomerase A6 precursor (P5)
          Length = 361

 Score =  177 bits (448), Expect = 9e-44
 Identities = 97/251 (38%), Positives = 135/251 (53%), Gaps = 4/251 (1%)
 Frame = +3

Query: 81  SDDVIDLTPSNFNDVKNGDELWFVEFYAPWCGHCQSLAPEWKKAASALKGV--VKVGAVD 254
           +DDV+ LT  +F      D+   VEFYAPWCGHC+ LAPE++K  ++ K    V +  VD
Sbjct: 22  ADDVVVLTDDSFEKEVGKDKGALVEFYAPWCGHCKKLAPEYEKLGASFKKAKSVLIAKVD 81

Query: 255 MDKYSSVGQPYNIQGFPTIKVFGKNKHSPKDYQGERNANAIVNNALKELEELVRSRLXXX 434
            D+  SV   Y + G+PTI+ F K    P+ Y+G RNA A+     KE    V+      
Sbjct: 82  CDEQKSVCTKYGVSGYPTIQWFPKGSLEPQKYEGPRNAEALAEYVNKEGGTNVK------ 135

Query: 435 XXXXXXXXXXXXXXXXXXXXXXEVIELTDSNFDELVLKSEEPWLVEFFAPWCGHCKNLKP 614
                                  V+ LT  NFDE+VL   +  LVEF+APWCGHCK+L P
Sbjct: 136 ----------------LAAVPQNVVVLTPDNFDEIVLDQNKDVLVEFYAPWCGHCKSLAP 179

Query: 615 HWDQAASELRGK--VKLGALDATVHNAVASRYGVQGYPTIKFFPAGVKTGEAQEYDGGRS 788
            +++ A+  + +  V +  LDA  H A+  +YGV G+PT+KFFP   K G   +YDGGR 
Sbjct: 180 TYEKVATVFKQEEGVVIANLDADAHKALGEKYGVSGFPTLKFFPKDNKAG--HDYDGGRD 237

Query: 789 SSDIVRWASDK 821
             D V + ++K
Sbjct: 238 LDDFVSFINEK 248

>sp|P34329|PDIA4_CAEEL Probable protein disulfide-isomerase A4 precursor (ERp-72 homolog)
          Length = 618

 Score =  163 bits (413), Expect = 1e-39
 Identities = 99/273 (36%), Positives = 149/273 (54%), Gaps = 7/273 (2%)
 Frame = +3

Query: 63  EALYSPSDDVIDLTPSNFNDVKNGDELWFVEFYAPWCGHCQSLAPEWKKAASALKGVVKV 242
           E  Y   + V+ LT  NF+     +    V+FYAPWCGHC+ LAPE++KA+S  K  + +
Sbjct: 29  ELNYEMDEGVVVLTDKNFDAFLKKNPSVLVKFYAPWCGHCKHLAPEYEKASS--KVSIPL 86

Query: 243 GAVDMDKYSSVGQPYNIQGFPTIKVFGKNKHSPKDYQGERNANAIVNNALKELEELVRSR 422
             VD    + +G+ + IQG+PT+K F K+   P DY G R+   IV        E V SR
Sbjct: 87  AKVDATVETELGKRFEIQGYPTLK-FWKDGKGPNDYDGGRDEAGIV--------EWVESR 137

Query: 423 LXXXXXXXXXXXXXXXXXXXXXXXXXEVIELTDSNFDELVLKSEEPWLVEFFAPWCGHCK 602
           +                         EV+ LT  NFD+ +  + E  LVEF+APWCGHCK
Sbjct: 138 V----------------DPNYKPPPEEVVTLTTENFDDFI-SNNELVLVEFYAPWCGHCK 180

Query: 603 NLKPHWDQAASELR---GKVKLGALDATVHNAVASRYGVQGYPTIKFFPAGVKTGEAQEY 773
            L P +++AA +L+    KVKLG +DAT+   + ++YGV GYPT+K     ++ G   +Y
Sbjct: 181 KLAPEYEKAAQKLKAQGSKVKLGKVDATIEKDLGTKYGVSGYPTMKI----IRNGRRFDY 236

Query: 774 DGGRSSSDIVRWASDKVVEQLPA----PELKEI 860
           +G R ++ I+++ +D   +  PA    P+LK++
Sbjct: 237 NGpreAAGIIKYMTD---QSKPAAKKLPKLKDV 266


 Score =  100 bits (248), Expect = 1e-20
 Identities = 72/234 (30%), Positives = 108/234 (46%), Gaps = 7/234 (2%)
 Frame = +3

Query: 504  VIELTDSNFDELVLKSEEPWLVEFFAPWCGHCKNLKPHWDQAASELRGKVKLGALDATVH 683
            V+ LTD NFD   LK     LV+F+APWCGHCK+L P +++A+S++   + L  +DATV 
Sbjct: 38   VVVLTDKNFDAF-LKKNPSVLVKFYAPWCGHCKHLAPEYEKASSKV--SIPLAKVDATVE 94

Query: 684  NAVASRYGVQGYPTIKFFPAGVKTGEAQEYDGGRSSSDIVRWASDKVVEQL--PAPELKE 857
              +  R+ +QGYPT+KF+  G    +   YDGGR  + IV W   +V      P  E+  
Sbjct: 95   TELGKRFEIQGYPTLKFWKDGKGPND---YDGGRDEAGIVEWVESRVDPNYKPPPEEVVT 151

Query: 858  ITNQDVLKSTCEDHQLCVIAVLPNILDCQSAC--RNSYLDTIRVSSDKYKANRWGWCWTE 1031
            +T ++       +  + V    P    C+            ++    K K  +       
Sbjct: 152  LTTENFDDFISNNELVLVEFYAPWCGHCKKLAPEYEKAAQKLKAQGSKVKLGKVD----- 206

Query: 1032 AMKLPAIEKAFG--IGGFGYPALVVV-NVRKMKYATLTGPFSQTGIQDFVRDVS 1184
                  IEK  G   G  GYP + ++ N R+  Y    GP    GI  ++ D S
Sbjct: 207  ----ATIEKDLGTKYGVSGYPTMKIIRNGRRFDY---NGpreAAGIIKYMTDQS 253


 Score = 77.8 bits (190), Expect = 7e-14
 Identities = 40/99 (40%), Positives = 62/99 (62%), Gaps = 3/99 (3%)
 Frame = +3

Query: 522 SNFDELVLKSEEPWLVEFFAPWCGHCKNLKPHW---DQAASELRGKVKLGALDATVHNAV 692
           SNFD++V    +  L+EF+APWCGHCK+ +  +    QA  + +  V L  +DAT+++A 
Sbjct: 507 SNFDKIVNDESKDVLIEFYAPWCGHCKSFESKYVELAQALKKTQPNVVLAKMDATINDA- 565

Query: 693 ASRYGVQGYPTIKFFPAGVKTGEAQEYDGGRSSSDIVRW 809
            S++ V+G+PTI F PAG K  E  +Y G R   D+ ++
Sbjct: 566 PSQFAVEGFPTIYFAPAG-KKSEPIKYSGNRDLEDLKKF 603


 Score = 54.7 bits (130), Expect = 7e-07
 Identities = 37/104 (35%), Positives = 52/104 (50%), Gaps = 7/104 (6%)
 Frame = +3

Query: 75  SPSDD---VIDLTPSNFNDVKNGDEL-WFVEFYAPWCGHCQSLAPEWKKAASALKGV-VK 239
           +P DD   V  +  SNF+ + N +     +EFYAPWCGHC+S   ++ + A ALK     
Sbjct: 493 APKDDKGPVKTVVGSNFDKIVNDESKDVLIEFYAPWCGHCKSFESKYVELAQALKKTQPN 552

Query: 240 VGAVDMD-KYSSVGQPYNIQGFPTIKVFGKNKHS-PKDYQGERN 365
           V    MD   +     + ++GFPTI      K S P  Y G R+
Sbjct: 553 VVLAKMDATINDAPSQFAVEGFPTIYFAPAGKKSEPIKYSGNRD 596

>sp|Q92249|ERP38_NEUCR Protein disulfide-isomerase erp38 precursor (ERp38)
          Length = 369

 Score =  154 bits (390), Expect = 5e-37
 Identities = 88/253 (34%), Positives = 137/253 (54%), Gaps = 9/253 (3%)
 Frame = +3

Query: 90  VIDLTPSNFNDV--KNGDELWFVEFYAPWCGHCQSLAPEWKKAASAL---KGVVKVGAVD 254
           V+DL PSNF+DV  K+G     VEF+APWCGHC++LAP +++ A+AL   K  V++  VD
Sbjct: 22  VLDLIPSNFDDVVLKSGKPT-LVEFFAPWCGHCKNLAPVYEELATALEYAKDKVQIAKVD 80

Query: 255 MDKYSSVGQPYNIQGFPTIKVFGKNKHSPKDYQGERNANAIVNNALKELEELVRSRLXXX 434
            D   ++G+ + +QGFPT+K F      P DY+G R+ +++ N   ++     R +    
Sbjct: 81  ADAERALGKRFGVQGFPTLKFFDGKSEQPVDYKGGRDLDSLSNFIAEKTGVKARKK---- 136

Query: 435 XXXXXXXXXXXXXXXXXXXXXXEVIELTDSNFDELVLKSEEPWLVEFFAPWCGHCKNLKP 614
                                  ++ + +    +  +  ++  LV F APWCGHCKNL P
Sbjct: 137 ------------------GSAPSLVNILNDATIKGAIGGDKNVLVAFTAPWCGHCKNLAP 178

Query: 615 HWDQAASELRGKVKLGA----LDATVHNAVASRYGVQGYPTIKFFPAGVKTGEAQEYDGG 782
            W++ A+      ++       DA      A+ YGV G+PTIKFFP G  T E  +Y+GG
Sbjct: 179 TWEKLAATFASDPEITIAKVDADAPTGKKSAAEYGVSGFPTIKFFPKGSTTPE--DYNGG 236

Query: 783 RSSSDIVRWASDK 821
           RS +D+V++ ++K
Sbjct: 237 RSEADLVKFLNEK 249


 Score =  107 bits (268), Expect = 7e-23
 Identities = 56/133 (42%), Positives = 83/133 (62%), Gaps = 7/133 (5%)
 Frame = +3

Query: 504 VIELTDSNFDELVLKSEEPWLVEFFAPWCGHCKNLKPHWDQAASEL---RGKVKLGALDA 674
           V++L  SNFD++VLKS +P LVEFFAPWCGHCKNL P +++ A+ L   + KV++  +DA
Sbjct: 22  VLDLIPSNFDDVVLKSGKPTLVEFFAPWCGHCKNLAPVYEELATALEYAKDKVQIAKVDA 81

Query: 675 TVHNAVASRYGVQGYPTIKFFPAGVKTGEAQEYDGGRSSSDIVRWASD----KVVEQLPA 842
               A+  R+GVQG+PT+KFF    K+ +  +Y GGR    +  + ++    K  ++  A
Sbjct: 82  DAERALGKRFGVQGFPTLKFFDG--KSEQPVDYKGGRDLDSLSNFIAEKTGVKARKKGSA 139

Query: 843 PELKEITNQDVLK 881
           P L  I N   +K
Sbjct: 140 PSLVNILNDATIK 152

>sp|Q00216|TIGA_ASPNG Protein disulfide-isomerase tigA precursor
          Length = 359

 Score =  145 bits (366), Expect = 3e-34
 Identities = 91/253 (35%), Positives = 128/253 (50%), Gaps = 9/253 (3%)
 Frame = +3

Query: 90  VIDLTPSNFNDV--KNGDELWFVEFYAPWCGHCQSLAPEWKKAASALKGV---VKVGAVD 254
           V+DL P NF+DV  K+G     VEF+APWCGHC++LAP +++   A       V VG VD
Sbjct: 21  VVDLVPKNFDDVVLKSGKPA-LVEFFAPWCGHCKNLAPVYEELGQAFAHASDKVTVGKVD 79

Query: 255 MDKYSSVGQPYNIQGFPTIKVFGKNKHSPKDYQGERNANAIVNNALKELEELVRSRLXXX 434
            D++  +G+ + +QGFPT+K F      P+DY+G R+        L+ L   +  +    
Sbjct: 80  ADEHRDLGRKFGVQGFPTLKWFDGKSDEPEDYKGGRD--------LESLSSFISEK---- 127

Query: 435 XXXXXXXXXXXXXXXXXXXXXXEVIELTDSNFDELVLKSEEPWLVEFFAPWCGHCKNLKP 614
                                 +V  L D+ F   V   +   LV F APWCGHCKNL P
Sbjct: 128 ---------TGVKPRGPKKEPSKVEMLNDATFKGAV-GGDNDVLVAFTAPWCGHCKNLAP 177

Query: 615 HWDQAASE--LRGKVKLGALDATVHN--AVASRYGVQGYPTIKFFPAGVKTGEAQEYDGG 782
            W+  A++  L   V +  +DA   N  A A   GV GYPTIKFFP G  + E+  Y+G 
Sbjct: 178 TWEALANDFVLEPNVVIAKVDADAENGKATAREQGVSGYPTIKFFPKG--STESVPYEGA 235

Query: 783 RSSSDIVRWASDK 821
           RS    + + ++K
Sbjct: 236 RSEQAFIDFLNEK 248


 Score =  104 bits (259), Expect = 7e-22
 Identities = 80/255 (31%), Positives = 119/255 (46%), Gaps = 14/255 (5%)
 Frame = +3

Query: 504  VIELTDSNFDELVLKSEEPWLVEFFAPWCGHCKNLKPHWD---QAASELRGKVKLGALDA 674
            V++L   NFD++VLKS +P LVEFFAPWCGHCKNL P ++   QA +    KV +G +DA
Sbjct: 21   VVDLVPKNFDDVVLKSGKPALVEFFAPWCGHCKNLAPVYEELGQAFAHASDKVTVGKVDA 80

Query: 675  TVHNAVASRYGVQGYPTIKFFPAGVKTGEAQEYDGGRSSSDIVRWASDKVVEQLPAPELK 854
              H  +  ++GVQG+PT+K+F    K+ E ++Y GGR    +  + S+K   +   P+ +
Sbjct: 81   DEHRDLGRKFGVQGFPTLKWFDG--KSDEPEDYKGGRDLESLSSFISEKTGVKPRGPKKE 138

Query: 855  ----EITNQDVLKSTC-EDHQLCVIAVLP------NILDCQSACRNSYLDTIRVSSDKYK 1001
                E+ N    K     D+ + V    P      N+     A  N ++    V   K  
Sbjct: 139  PSKVEMLNDATFKGAVGGDNDVLVAFTAPWCGHCKNLAPTWEALANDFVLEPNVVIAKVD 198

Query: 1002 ANRWGWCWTEAMKLPAIEKAFGIGGFGYPALVVVNVRKMKYATLTGPFSQTGIQDFVRDV 1181
            A+       E  K  A E+    G  GYP +        +     G  S+    DF+ + 
Sbjct: 199  AD------AENGKATAREQ----GVSGYPTIKFFPKGSTESVPYEGARSEQAFIDFLNE- 247

Query: 1182 SLGRGSTAAIVGEGL 1226
               +  T   VG GL
Sbjct: 248  ---KTGTHRTVGGGL 259

  Database: Non-redundant SwissProt sequences
    Posted date:  Dec 6, 2005  7:40 AM
  Number of letters in database: 68,354,980
  Number of sequences in database:  184,735
  
  Database: swissprot.01
    Posted date:  Dec 6, 2005  8:18 AM
  Number of letters in database: 66,202,850
  Number of sequences in database:  184,431
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 159,779,831
Number of Sequences: 369166
Number of extensions: 3238647
Number of successful extensions: 10495
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 9211
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 10183
length of database: 68,354,980
effective HSP length: 115
effective length of database: 47,110,455
effective search space used: 17477978805
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)

Cluster detail

DrC_00748

  1. Dr_sW_019_H21
  2. Dr_sW_011_J07
  3. Dr_sW_018_J03
  4. Dr_sW_020_L08
  5. Dr_sW_005_G24
  6. Dr_sW_002_F03
  7. Dr_sW_002_G13
  8. Dr_sW_002_P02
  9. Dr_sW_010_N24
  10. Dr_sW_021_P15