Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_010_N24
(444 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q922R8|PDIA6_MOUSE Protein disulfide-isomerase A6 precur... 125 4e-29
sp|Q63081|PDIA6_RAT Protein disulfide-isomerase A6 precurso... 124 7e-29
sp|P38660|PDIA6_MESAU Protein disulfide-isomerase A6 precur... 120 2e-27
sp|Q15084|PDIA6_HUMAN Protein disulfide-isomerase A6 precur... 119 3e-27
sp|Q5R6T1|PDIA6_PONPY Protein disulfide-isomerase A6 precursor 119 3e-27
sp|Q11067|PDIA6_CAEEL Probable protein disulfide-isomerase ... 114 7e-26
sp|O54943|PER2_MOUSE Period circadian protein 2 (mPER2) 31 1.4
sp|Q9Z301|PER2_RAT Period circadian protein 2 (rPER2) 31 1.4
sp|P46891|COF_ECOLI Protein cof 30 3.1
sp|P55871|IF2B_MALDO Eukaryotic translation initiation fact... 29 5.3
>sp|Q922R8|PDIA6_MOUSE Protein disulfide-isomerase A6 precursor (Thioredoxin
domain-containing protein 7)
Length = 440
Score = 125 bits (314), Expect = 4e-29
Identities = 58/105 (55%), Positives = 77/105 (73%), Gaps = 1/105 (0%)
Frame = +1
Query: 16 WTEAMKLPAIEKAFGIGGFGYPALVVVNVRKMKYATLTGPFSQTGIQDFVRDVSLGRGST 195
WTEA +E A GIGGFGYPA+ +N RKMK+A L G FS+ GI +F+R++S GRGST
Sbjct: 336 WTEAGAQYELENALGIGGFGYPAMAAINARKMKFALLKGSFSEQGINEFLRELSFGRGST 395
Query: 196 AAIVGEGLPAITPVDPWDGKDGEMPKEEEIDLSELGIEE-PKSEL 327
A + G P ITP +PWDGKDGE+P E++IDLS++ +++ K EL
Sbjct: 396 APVGGGSFPTITprePWDGKDGELPVEDDIDLSDVELDDLEKDEL 440
>sp|Q63081|PDIA6_RAT Protein disulfide-isomerase A6 precursor (Protein disulfide
isomerase P5) (Calcium-binding protein 1) (CaBP1)
(Thioredoxin domain-containing protein 7)
Length = 440
Score = 124 bits (312), Expect = 7e-29
Identities = 58/105 (55%), Positives = 77/105 (73%), Gaps = 1/105 (0%)
Frame = +1
Query: 16 WTEAMKLPAIEKAFGIGGFGYPALVVVNVRKMKYATLTGPFSQTGIQDFVRDVSLGRGST 195
WTEA +E A GIGGFGYPA+ +N RKMK+A L G FS+ GI +F+R++S GRGST
Sbjct: 336 WTEAGAQYELENALGIGGFGYPAMAAINARKMKFALLKGSFSEQGINEFLRELSFGRGST 395
Query: 196 AAIVGEGLPAITPVDPWDGKDGEMPKEEEIDLSELGIEE-PKSEL 327
A + G P ITP +PWDGKDGE+P E++IDLS++ +++ K EL
Sbjct: 396 APVGGGSFPNITprePWDGKDGELPVEDDIDLSDVELDDLEKDEL 440
>sp|P38660|PDIA6_MESAU Protein disulfide-isomerase A6 precursor (Protein disulfide
isomerase P5)
Length = 439
Score = 120 bits (300), Expect = 2e-27
Identities = 56/105 (53%), Positives = 76/105 (72%), Gaps = 1/105 (0%)
Frame = +1
Query: 16 WTEAMKLPAIEKAFGIGGFGYPALVVVNVRKMKYATLTGPFSQTGIQDFVRDVSLGRGST 195
WTEA +E A GIGGFGYPA+ +N RKMK+A L G FS+ GI +F+R++S GR ST
Sbjct: 335 WTEAGAQSELENALGIGGFGYPAMARINARKMKFALLKGSFSEQGINEFLRELSFGRAST 394
Query: 196 AAIVGEGLPAITPVDPWDGKDGEMPKEEEIDLSELGIEE-PKSEL 327
A + G PAIT +PWDG+DGE+P E++IDLS++ +++ K EL
Sbjct: 395 APVGGGSFPAITAREPWDGRDGELPVEDDIDLSDVELDDLEKDEL 439
>sp|Q15084|PDIA6_HUMAN Protein disulfide-isomerase A6 precursor (Protein disulfide
isomerase P5) (Thioredoxin domain-containing protein 7)
Length = 440
Score = 119 bits (298), Expect = 3e-27
Identities = 52/99 (52%), Positives = 72/99 (72%)
Frame = +1
Query: 16 WTEAMKLPAIEKAFGIGGFGYPALVVVNVRKMKYATLTGPFSQTGIQDFVRDVSLGRGST 195
WTEA +E A GIGGFGYPA+ +N RKMK+A L G FS+ GI +F+R++S GRGST
Sbjct: 336 WTEAGAQSELETALGIGGFGYPAMAAINARKMKFALLKGSFSEQGINEFLRELSFGRGST 395
Query: 196 AAIVGEGLPAITPVDPWDGKDGEMPKEEEIDLSELGIEE 312
A + G P I +PWDG+DGE+P E++IDLS++ +++
Sbjct: 396 APVGGGAFPTIVEREPWDGRDGELPVEDDIDLSDVELDD 434
>sp|Q5R6T1|PDIA6_PONPY Protein disulfide-isomerase A6 precursor
Length = 440
Score = 119 bits (298), Expect = 3e-27
Identities = 52/99 (52%), Positives = 72/99 (72%)
Frame = +1
Query: 16 WTEAMKLPAIEKAFGIGGFGYPALVVVNVRKMKYATLTGPFSQTGIQDFVRDVSLGRGST 195
WTEA +E A GIGGFGYPA+ +N RKMK+A L G FS+ GI +F+R++S GRGST
Sbjct: 336 WTEAGAQSELETALGIGGFGYPAMAAINARKMKFALLKGSFSEQGINEFLRELSFGRGST 395
Query: 196 AAIVGEGLPAITPVDPWDGKDGEMPKEEEIDLSELGIEE 312
A + G P I +PWDG+DGE+P E++IDLS++ +++
Sbjct: 396 APVGGGAFPTIVEREPWDGRDGELPVEDDIDLSDVELDD 434
>sp|Q11067|PDIA6_CAEEL Probable protein disulfide-isomerase A6 precursor
Length = 440
Score = 114 bits (286), Expect = 7e-26
Identities = 50/104 (48%), Positives = 74/104 (71%)
Frame = +1
Query: 16 WTEAMKLPAIEKAFGIGGFGYPALVVVNVRKMKYATLTGPFSQTGIQDFVRDVSLGRGST 195
W E PA+E++F +GGFGYPA+ +N RK KYA L G F + GI +F+RD+S G+G T
Sbjct: 339 WVEGAAQPALEESFEVGGFGYPAMTALNFRKNKYAVLKGSFGKDGIHEFLRDLSYGKGRT 398
Query: 196 AAIVGEGLPAITPVDPWDGKDGEMPKEEEIDLSELGIEEPKSEL 327
+++ G+G P I + WDGKDG +P E++IDLS++ ++ K+EL
Sbjct: 399 SSLRGDGFPKIQKTEKWDGKDGALPAEDDIDLSDIDLD--KTEL 440
>sp|O54943|PER2_MOUSE Period circadian protein 2 (mPER2)
Length = 1257
Score = 30.8 bits (68), Expect = 1.4
Identities = 13/29 (44%), Positives = 16/29 (55%)
Frame = +2
Query: 329 KKYHLGSLDPLVHAGGLPTGDDVYSCYCC 415
++ L + P VH GGLPT DV C C
Sbjct: 1185 QRRELREVHPWVHTGGLPTAIDVTGCVYC 1213
>sp|Q9Z301|PER2_RAT Period circadian protein 2 (rPER2)
Length = 1257
Score = 30.8 bits (68), Expect = 1.4
Identities = 13/29 (44%), Positives = 16/29 (55%)
Frame = +2
Query: 329 KKYHLGSLDPLVHAGGLPTGDDVYSCYCC 415
++ L + P VH GGLPT DV C C
Sbjct: 1185 QRRELREVHPWVHTGGLPTAIDVTGCVYC 1213
>sp|P46891|COF_ECOLI Protein cof
Length = 272
Score = 29.6 bits (65), Expect = 3.1
Identities = 13/40 (32%), Positives = 24/40 (60%)
Frame = +1
Query: 10 EGWTEAMKLPAIEKAFGIGGFGYPALVVVNVRKMKYATLT 129
+GW ++PA+ +AF GF Y +++V+KM ++T
Sbjct: 108 DGWFTGKEIPALLQAFVYSGFRYQ---IIDVKKMPLGSVT 144
>sp|P55871|IF2B_MALDO Eukaryotic translation initiation factor 2 beta subunit
(eIF-2-beta)
Length = 271
Score = 28.9 bits (63), Expect = 5.3
Identities = 12/27 (44%), Positives = 16/27 (59%)
Frame = +1
Query: 208 GEGLPAITPVDPWDGKDGEMPKEEEID 288
GEG+ TP PW+G D + EE +D
Sbjct: 98 GEGIVLETPSYPWEGSDRDYTYEELLD 124
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 53,036,404
Number of Sequences: 369166
Number of extensions: 1026436
Number of successful extensions: 3456
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3344
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3451
length of database: 68,354,980
effective HSP length: 100
effective length of database: 49,881,480
effective search space used: 2344429560
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)