Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_011_J07
(856 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q11067|PDIA6_CAEEL Probable protein disulfide-isomerase ... 317 2e-86
sp|Q922R8|PDIA6_MOUSE Protein disulfide-isomerase A6 precur... 295 1e-79
sp|Q63081|PDIA6_RAT Protein disulfide-isomerase A6 precurso... 292 7e-79
sp|Q15084|PDIA6_HUMAN Protein disulfide-isomerase A6 precur... 292 9e-79
sp|Q5R6T1|PDIA6_PONPY Protein disulfide-isomerase A6 precursor 289 8e-78
sp|P38660|PDIA6_MESAU Protein disulfide-isomerase A6 precur... 284 2e-76
sp|Q17770|PDI2_CAEEL Protein disulfide-isomerase 2 precurso... 114 3e-25
sp|Q92249|ERP38_NEUCR Protein disulfide-isomerase erp38 pre... 107 3e-23
sp|O22263|PDIA6_ARATH Probable protein disulfide-isomerase ... 105 2e-22
sp|P54399|PDI_DROME Protein disulfide-isomerase precursor (... 104 3e-22
>sp|Q11067|PDIA6_CAEEL Probable protein disulfide-isomerase A6 precursor
Length = 440
Score = 317 bits (813), Expect = 2e-86
Identities = 139/245 (56%), Positives = 187/245 (76%)
Frame = +1
Query: 115 EVIELTDSNFDELVLKSEEPWLVEFFAPWCGHCKNLKPHWDQAASELRGKVKLGALDATV 294
EV+ELTD+NF++LVL S++ WLVEFFAPWCGHCK+L+P W AASEL+GKV+LGALDATV
Sbjct: 165 EVVELTDANFEDLVLNSKDIWLVEFFAPWCGHCKSLEPQWKAAASELKGKVRLGALDATV 224
Query: 295 HNAVASRYGVQGYPTIKFFPAGVKTGEAQEYDGGRSSSDIVRWASDKVVEQLPAPELKEI 474
H VA+++ ++G+PTIK+F G +AQ+YDGGR SSDIV WAS + E +PAPE+ E
Sbjct: 225 HTVVANKFAIRGFPTIKYFAPGSDVSDAQDYDGGRQSSDIVAWASARAQENMPAPEVFEG 284
Query: 475 TNQDVLKSTCEDHQLCVIAVLPNILDCQSACRNSYLDTIRVSSDKYKANRWGWCWTEAMK 654
NQ V++ C++ QLC+ A LP+ILDCQS CRN+YL ++ S+K+K N WGW W E
Sbjct: 285 INQQVVEDACKEKQLCIFAFLPHILDCQSECRNNYLAMLKEQSEKFKKNLWGWIWVEGAA 344
Query: 655 LPAIEKAFGIGGFGYPALVVVNVRKMKYATLTGPFSQTGIQDFVRDVSLGRGSTAAIVGE 834
PA+E++F +GGFGYPA+ +N RK KYA L G F + GI +F+RD+S G+G T+++ G+
Sbjct: 345 QPALEESFEVGGFGYPAMTALNFRKNKYAVLKGSFGKDGIHEFLRDLSYGKGRTSSLRGD 404
Query: 835 GLPAI 849
G P I
Sbjct: 405 GFPKI 409
Score = 108 bits (269), Expect = 2e-23
Identities = 48/100 (48%), Positives = 71/100 (71%)
Frame = +1
Query: 115 EVIELTDSNFDELVLKSEEPWLVEFFAPWCGHCKNLKPHWDQAASELRGKVKLGALDATV 294
+V+ELT++NF V+ S++ W+VEF+APWCGHCK+L P + +AAS L+G K+GA+D T
Sbjct: 25 DVVELTEANFQSKVINSDDIWIVEFYAPWCGHCKSLVPEYKKAASALKGVAKVGAVDMTQ 84
Query: 295 HNAVASRYGVQGYPTIKFFPAGVKTGEAQEYDGGRSSSDI 414
H +V Y VQG+PT+K F A K + +Y+G R++ I
Sbjct: 85 HQSVGGPYNVQGFPTLKIFGADKK--KPTDYNGQRTAQAI 122
>sp|Q922R8|PDIA6_MOUSE Protein disulfide-isomerase A6 precursor (Thioredoxin
domain-containing protein 7)
Length = 440
Score = 295 bits (754), Expect = 1e-79
Identities = 141/251 (56%), Positives = 179/251 (71%), Gaps = 4/251 (1%)
Frame = +1
Query: 115 EVIELTDSNFDELVLKSEEPWLVEFFAPWCGHCKNLKPHWDQAASELR----GKVKLGAL 282
+V+ELTD FD+ VL SE+ W+VEF+APWCGHCKNL+P W AA+E++ GKVKL A+
Sbjct: 161 DVVELTDDTFDKNVLDSEDVWMVEFYAPWCGHCKNLEPEWAAAATEVKEQTKGKVKLAAV 220
Query: 283 DATVHNAVASRYGVQGYPTIKFFPAGVKTGEAQEYDGGRSSSDIVRWASDKVVEQLPAPE 462
DATV+ +ASRYG++G+PTIK F G +YDGGR+ SDIV A D + P PE
Sbjct: 221 DATVNQVLASRYGIKGFPTIKIFQKGESP---VDYDGGRTRSDIVSRALDLFSDNAPPPE 277
Query: 463 LKEITNQDVLKSTCEDHQLCVIAVLPNILDCQSACRNSYLDTIRVSSDKYKANRWGWCWT 642
L EI N+D+ K TCE+HQLCV+AVLP+ILD +A RNSYL+ + +DKYK WGW WT
Sbjct: 278 LLEIINEDIAKKTCEEHQLCVVAVLPHILDTGAAGRNSYLEVLLKLADKYKKKMWGWLWT 337
Query: 643 EAMKLPAIEKAFGIGGFGYPALVVVNVRKMKYATLTGPFSQTGIQDFVRDVSLGRGSTAA 822
EA +E A GIGGFGYPA+ +N RKMK+A L G FS+ GI +F+R++S GRGSTA
Sbjct: 338 EAGAQYELENALGIGGFGYPAMAAINARKMKFALLKGSFSEQGINEFLRELSFGRGSTAP 397
Query: 823 IVGEGLPAITP 855
+ G P ITP
Sbjct: 398 VGGGSFPTITP 408
Score = 114 bits (284), Expect = 4e-25
Identities = 51/101 (50%), Positives = 72/101 (71%)
Frame = +1
Query: 115 EVIELTDSNFDELVLKSEEPWLVEFFAPWCGHCKNLKPHWDQAASELRGKVKLGALDATV 294
+VIELT SNF+ V++S+ WLVEF+APWCGHC+ L P W +AA+ L+ VK+GA++A
Sbjct: 26 DVIELTPSNFNREVIQSDGLWLVEFYAPWCGHCQRLTPEWKKAATALKDVVKVGAVNADK 85
Query: 295 HNAVASRYGVQGYPTIKFFPAGVKTGEAQEYDGGRSSSDIV 417
H ++ +YGVQG+PTIK F G + ++Y GGR+ IV
Sbjct: 86 HQSLGGQYGVQGFPTIKIF--GANKNKPEDYQGGRTGEAIV 124
>sp|Q63081|PDIA6_RAT Protein disulfide-isomerase A6 precursor (Protein disulfide
isomerase P5) (Calcium-binding protein 1) (CaBP1)
(Thioredoxin domain-containing protein 7)
Length = 440
Score = 292 bits (748), Expect = 7e-79
Identities = 140/251 (55%), Positives = 178/251 (70%), Gaps = 4/251 (1%)
Frame = +1
Query: 115 EVIELTDSNFDELVLKSEEPWLVEFFAPWCGHCKNLKPHWDQAASELR----GKVKLGAL 282
+V+ELTD FD+ VL SE+ W+VEF+APWCGHCKNL+P W AA+E++ GKVKL A+
Sbjct: 161 DVVELTDDTFDKNVLDSEDVWMVEFYAPWCGHCKNLEPEWAAAATEVKEQTKGKVKLAAV 220
Query: 283 DATVHNAVASRYGVQGYPTIKFFPAGVKTGEAQEYDGGRSSSDIVRWASDKVVEQLPAPE 462
DATV+ +ASRYG++G+PTIK F G +YDGGR+ SDIV A D + P PE
Sbjct: 221 DATVNQVLASRYGIKGFPTIKIFQKGESP---VDYDGGRTRSDIVSRALDLFSDNAPPPE 277
Query: 463 LKEITNQDVLKSTCEDHQLCVIAVLPNILDCQSACRNSYLDTIRVSSDKYKANRWGWCWT 642
L EI N+D+ K TCE+HQLCV+AVLP+ILD + RNSYL+ + +DKYK WGW WT
Sbjct: 278 LLEIINEDIAKKTCEEHQLCVVAVLPHILDTGATGRNSYLEVLLKLADKYKKKMWGWLWT 337
Query: 643 EAMKLPAIEKAFGIGGFGYPALVVVNVRKMKYATLTGPFSQTGIQDFVRDVSLGRGSTAA 822
EA +E A GIGGFGYPA+ +N RKMK+A L G FS+ GI +F+R++S GRGSTA
Sbjct: 338 EAGAQYELENALGIGGFGYPAMAAINARKMKFALLKGSFSEQGINEFLRELSFGRGSTAP 397
Query: 823 IVGEGLPAITP 855
+ G P ITP
Sbjct: 398 VGGGSFPNITP 408
Score = 115 bits (289), Expect = 1e-25
Identities = 52/101 (51%), Positives = 72/101 (71%)
Frame = +1
Query: 115 EVIELTDSNFDELVLKSEEPWLVEFFAPWCGHCKNLKPHWDQAASELRGKVKLGALDATV 294
+VIELT SNF+ V++S+ WLVEF+APWCGHC+ L P W +AAS L+ VK+GA++A
Sbjct: 26 DVIELTPSNFNREVIQSDSLWLVEFYAPWCGHCQRLTPEWKKAASALKDVVKVGAVNADK 85
Query: 295 HNAVASRYGVQGYPTIKFFPAGVKTGEAQEYDGGRSSSDIV 417
H ++ +YGVQG+PTIK F G + ++Y GGR+ IV
Sbjct: 86 HQSLGGQYGVQGFPTIKIF--GANKNKPEDYQGGRTGEAIV 124
>sp|Q15084|PDIA6_HUMAN Protein disulfide-isomerase A6 precursor (Protein disulfide
isomerase P5) (Thioredoxin domain-containing protein 7)
Length = 440
Score = 292 bits (747), Expect = 9e-79
Identities = 141/249 (56%), Positives = 178/249 (71%), Gaps = 4/249 (1%)
Frame = +1
Query: 115 EVIELTDSNFDELVLKSEEPWLVEFFAPWCGHCKNLKPHWDQAASELR----GKVKLGAL 282
+VIELTD +FD+ VL SE+ W+VEF+APWCGHCKNL+P W AASE++ GKVKL A+
Sbjct: 161 DVIELTDDSFDKNVLDSEDVWMVEFYAPWCGHCKNLEPEWAAAASEVKEQTKGKVKLAAV 220
Query: 283 DATVHNAVASRYGVQGYPTIKFFPAGVKTGEAQEYDGGRSSSDIVRWASDKVVEQLPAPE 462
DATV+ +ASRYG++G+PTIK F G +YDGGR+ SDIV A D + P PE
Sbjct: 221 DATVNQVLASRYGIRGFPTIKIFQKGESP---VDYDGGRTRSDIVSRALDLFSDNAPPPE 277
Query: 463 LKEITNQDVLKSTCEDHQLCVIAVLPNILDCQSACRNSYLDTIRVSSDKYKANRWGWCWT 642
L EI N+D+ K TCE+HQLCV+AVLP+ILD +A RNSYL+ + +DKYK WGW WT
Sbjct: 278 LLEIINEDIAKRTCEEHQLCVVAVLPHILDTGAAGRNSYLEVLLKLADKYKKKMWGWLWT 337
Query: 643 EAMKLPAIEKAFGIGGFGYPALVVVNVRKMKYATLTGPFSQTGIQDFVRDVSLGRGSTAA 822
EA +E A GIGGFGYPA+ +N RKMK+A L G FS+ GI +F+R++S GRGSTA
Sbjct: 338 EAGAQSELETALGIGGFGYPAMAAINARKMKFALLKGSFSEQGINEFLRELSFGRGSTAP 397
Query: 823 IVGEGLPAI 849
+ G P I
Sbjct: 398 VGGGAFPTI 406
Score = 115 bits (289), Expect = 1e-25
Identities = 52/101 (51%), Positives = 72/101 (71%)
Frame = +1
Query: 115 EVIELTDSNFDELVLKSEEPWLVEFFAPWCGHCKNLKPHWDQAASELRGKVKLGALDATV 294
+VIELT SNF+ V++S+ WLVEF+APWCGHC+ L P W +AA+ L+ VK+GA+DA
Sbjct: 26 DVIELTPSNFNREVIQSDSLWLVEFYAPWCGHCQRLTPEWKKAATALKDVVKVGAVDADK 85
Query: 295 HNAVASRYGVQGYPTIKFFPAGVKTGEAQEYDGGRSSSDIV 417
H+++ +YGVQG+PTIK F G ++Y GGR+ IV
Sbjct: 86 HHSLGGQYGVQGFPTIKIF--GSNKNRPEDYQGGRTGEAIV 124
>sp|Q5R6T1|PDIA6_PONPY Protein disulfide-isomerase A6 precursor
Length = 440
Score = 289 bits (739), Expect = 8e-78
Identities = 139/249 (55%), Positives = 178/249 (71%), Gaps = 4/249 (1%)
Frame = +1
Query: 115 EVIELTDSNFDELVLKSEEPWLVEFFAPWCGHCKNLKPHWDQAASELR----GKVKLGAL 282
+VIELTD +FD+ VL SE+ W+VEF+APWCGHCKNL+P W AASE++ GKVKL A+
Sbjct: 161 DVIELTDDSFDKNVLDSEDVWMVEFYAPWCGHCKNLEPEWAAAASEVKEQTKGKVKLAAV 220
Query: 283 DATVHNAVASRYGVQGYPTIKFFPAGVKTGEAQEYDGGRSSSDIVRWASDKVVEQLPAPE 462
DATV+ +ASRYG++G+PTIK F G +YDGGR+ SDIV A D + P PE
Sbjct: 221 DATVNQVLASRYGIRGFPTIKIFQKGESP---VDYDGGRTRSDIVSRALDLFSDNAPPPE 277
Query: 463 LKEITNQDVLKSTCEDHQLCVIAVLPNILDCQSACRNSYLDTIRVSSDKYKANRWGWCWT 642
L EI ++D+ K TCE+HQLCV++VLP+ILD +A RNSYL+ + +DKYK WGW WT
Sbjct: 278 LLEIISEDIAKRTCEEHQLCVVSVLPHILDTGAAGRNSYLEVLLKLADKYKKKMWGWLWT 337
Query: 643 EAMKLPAIEKAFGIGGFGYPALVVVNVRKMKYATLTGPFSQTGIQDFVRDVSLGRGSTAA 822
EA +E A GIGGFGYPA+ +N RKMK+A L G FS+ GI +F+R++S GRGSTA
Sbjct: 338 EAGAQSELETALGIGGFGYPAMAAINARKMKFALLKGSFSEQGINEFLRELSFGRGSTAP 397
Query: 823 IVGEGLPAI 849
+ G P I
Sbjct: 398 VGGGAFPTI 406
Score = 115 bits (289), Expect = 1e-25
Identities = 52/101 (51%), Positives = 72/101 (71%)
Frame = +1
Query: 115 EVIELTDSNFDELVLKSEEPWLVEFFAPWCGHCKNLKPHWDQAASELRGKVKLGALDATV 294
+VIELT SNF+ V++S+ WLVEF+APWCGHC+ L P W +AA+ L+ VK+GA+DA
Sbjct: 26 DVIELTPSNFNREVIQSDSLWLVEFYAPWCGHCQRLTPEWKKAATALKDVVKVGAVDADK 85
Query: 295 HNAVASRYGVQGYPTIKFFPAGVKTGEAQEYDGGRSSSDIV 417
H+++ +YGVQG+PTIK F G ++Y GGR+ IV
Sbjct: 86 HHSLGGQYGVQGFPTIKIF--GSNKNRPEDYQGGRTGEAIV 124
>sp|P38660|PDIA6_MESAU Protein disulfide-isomerase A6 precursor (Protein disulfide
isomerase P5)
Length = 439
Score = 284 bits (727), Expect = 2e-76
Identities = 141/251 (56%), Positives = 179/251 (71%), Gaps = 5/251 (1%)
Frame = +1
Query: 115 EVIELTDSNFDELVLKSEEPWLVEFFAPWCGHCKNLKPHWDQAASELR----GKVKLGAL 282
+VIELTD FD+ VL S++ W+VEF+APWCGHCKNL+P W AA+E++ GKVKL A+
Sbjct: 161 DVIELTDDTFDKNVLDSDDVWMVEFYAPWCGHCKNLEPEWATAATEVKEQTKGKVKLAAV 220
Query: 283 DATVHNAVASRYGVQGYPTIKFFPAGVKTGEAQ-EYDGGRSSSDIVRWASDKVVEQLPAP 459
DATV+ +A+RYG++G+PTIK F + GEA +YDGGR+ SDIV A D + P P
Sbjct: 221 DATVNQVLANRYGIRGFPTIKIF----QKGEAPVDYDGGRTRSDIVSRALDLFSDNAPPP 276
Query: 460 ELKEITNQDVLKSTCEDHQLCVIAVLPNILDCQSACRNSYLDTIRVSSDKYKANRWGWCW 639
EL EI N+DV K CE+HQLCV+AVLP+ILD A RNSYL+ + +DKYK WGW W
Sbjct: 277 ELLEIINEDVAKKMCEEHQLCVVAVLPHILDT-GAARNSYLEILLKLADKYKKKMWGWLW 335
Query: 640 TEAMKLPAIEKAFGIGGFGYPALVVVNVRKMKYATLTGPFSQTGIQDFVRDVSLGRGSTA 819
TEA +E A GIGGFGYPA+ +N RKMK+A L G FS+ GI +F+R++S GR STA
Sbjct: 336 TEAGAQSELENALGIGGFGYPAMARINARKMKFALLKGSFSEQGINEFLRELSFGRASTA 395
Query: 820 AIVGEGLPAIT 852
+ G PAIT
Sbjct: 396 PVGGGSFPAIT 406
Score = 115 bits (289), Expect = 1e-25
Identities = 52/101 (51%), Positives = 71/101 (70%)
Frame = +1
Query: 115 EVIELTDSNFDELVLKSEEPWLVEFFAPWCGHCKNLKPHWDQAASELRGKVKLGALDATV 294
+VIELT SNF+ V++S WLVEF+APWCGHC+ L P W +AA+ L+ VK+GA+DA
Sbjct: 26 DVIELTPSNFNREVIQSNSLWLVEFYAPWCGHCQRLTPEWKKAATALKDVVKVGAVDADK 85
Query: 295 HNAVASRYGVQGYPTIKFFPAGVKTGEAQEYDGGRSSSDIV 417
H ++ +YGVQG+PTIK F G + ++Y GGR+ IV
Sbjct: 86 HQSLGGQYGVQGFPTIKIF--GANKNKPEDYQGGRTGEAIV 124
>sp|Q17770|PDI2_CAEEL Protein disulfide-isomerase 2 precursor (PDI 1) (Prolyl
4-hydroxylase beta subunit)
Length = 493
Score = 114 bits (286), Expect = 3e-25
Identities = 62/140 (44%), Positives = 84/140 (60%), Gaps = 3/140 (2%)
Frame = +1
Query: 118 VIELTDSNFDELVLKSEEPWLVEFFAPWCGHCKNLKPHWDQAASELR---GKVKLGALDA 288
VI LT NFDE V+ E LVEF+APWCGHCK+L P + +AA++L+ +KLG LDA
Sbjct: 25 VIVLTKDNFDE-VINGNEFILVEFYAPWCGHCKSLAPEYAKAATQLKEEGSDIKLGKLDA 83
Query: 289 TVHNAVASRYGVQGYPTIKFFPAGVKTGEAQEYDGGRSSSDIVRWASDKVVEQLPAPELK 468
TVH V+S++ V+GYPT+K F + G+ QEY+GGR I+ W K P K
Sbjct: 84 TVHGEVSSKFEVRGYPTLKLF----RNGKPQEYNGGRDHDSIIAWLKKKT-----GPVAK 134
Query: 469 EITNQDVLKSTCEDHQLCVI 528
+ + D +K E + VI
Sbjct: 135 PLADADAVKELQESADVVVI 154
Score = 71.6 bits (174), Expect = 3e-12
Identities = 37/114 (32%), Positives = 60/114 (52%), Gaps = 2/114 (1%)
Frame = +1
Query: 127 LTDSNFDELVLKSEEPWLVEFFAPWCGHCKNLKPHWDQAASELRG--KVKLGALDATVHN 300
L NF+++ + + LVEF+APWCGHCK L P WD+ + + + +D+T++
Sbjct: 368 LVGKNFEQVARDNTKNVLVEFYAPWCGHCKQLAPTWDKLGEKFADDESIVIAKMDSTLNE 427
Query: 301 AVASRYGVQGYPTIKFFPAGVKTGEAQEYDGGRSSSDIVRWASDKVVEQLPAPE 462
+ +Q +PTIKFFPAG + + +Y G R+ ++ E A E
Sbjct: 428 VEDVK--IQSFPTIKFFPAG--SNKVVDYTGDRTIEGFTKFLETNGKEGAGASE 477
>sp|Q92249|ERP38_NEUCR Protein disulfide-isomerase erp38 precursor (ERp38)
Length = 369
Score = 107 bits (268), Expect = 3e-23
Identities = 56/133 (42%), Positives = 83/133 (62%), Gaps = 7/133 (5%)
Frame = +1
Query: 118 VIELTDSNFDELVLKSEEPWLVEFFAPWCGHCKNLKPHWDQAASEL---RGKVKLGALDA 288
V++L SNFD++VLKS +P LVEFFAPWCGHCKNL P +++ A+ L + KV++ +DA
Sbjct: 22 VLDLIPSNFDDVVLKSGKPTLVEFFAPWCGHCKNLAPVYEELATALEYAKDKVQIAKVDA 81
Query: 289 TVHNAVASRYGVQGYPTIKFFPAGVKTGEAQEYDGGRSSSDIVRWASD----KVVEQLPA 456
A+ R+GVQG+PT+KFF K+ + +Y GGR + + ++ K ++ A
Sbjct: 82 DAERALGKRFGVQGFPTLKFFDG--KSEQPVDYKGGRDLDSLSNFIAEKTGVKARKKGSA 139
Query: 457 PELKEITNQDVLK 495
P L I N +K
Sbjct: 140 PSLVNILNDATIK 152
Score = 84.3 bits (207), Expect = 4e-16
Identities = 41/90 (45%), Positives = 56/90 (62%), Gaps = 4/90 (4%)
Frame = +1
Query: 178 LVEFFAPWCGHCKNLKPHWDQAASELRGKVKLGA----LDATVHNAVASRYGVQGYPTIK 345
LV F APWCGHCKNL P W++ A+ ++ DA A+ YGV G+PTIK
Sbjct: 162 LVAFTAPWCGHCKNLAPTWEKLAATFASDPEITIAKVDADAPTGKKSAAEYGVSGFPTIK 221
Query: 346 FFPAGVKTGEAQEYDGGRSSSDIVRWASDK 435
FFP G T E +Y+GGRS +D+V++ ++K
Sbjct: 222 FFPKGSTTPE--DYNGGRSEADLVKFLNEK 249
>sp|O22263|PDIA6_ARATH Probable protein disulfide-isomerase A6 precursor (P5)
Length = 361
Score = 105 bits (262), Expect = 2e-22
Identities = 50/108 (46%), Positives = 70/108 (64%), Gaps = 2/108 (1%)
Frame = +1
Query: 118 VIELTDSNFDELVLKSEEPWLVEFFAPWCGHCKNLKPHWDQAASELRGK--VKLGALDAT 291
V+ LT NFDE+VL + LVEF+APWCGHCK+L P +++ A+ + + V + LDA
Sbjct: 143 VVVLTPDNFDEIVLDQNKDVLVEFYAPWCGHCKSLAPTYEKVATVFKQEEGVVIANLDAD 202
Query: 292 VHNAVASRYGVQGYPTIKFFPAGVKTGEAQEYDGGRSSSDIVRWASDK 435
H A+ +YGV G+PT+KFFP K G +YDGGR D V + ++K
Sbjct: 203 AHKALGEKYGVSGFPTLKFFPKDNKAG--HDYDGGRDLDDFVSFINEK 248
Score = 82.0 bits (201), Expect = 2e-15
Identities = 40/107 (37%), Positives = 67/107 (62%), Gaps = 2/107 (1%)
Frame = +1
Query: 115 EVIELTDSNFDELVLKSEEPWLVEFFAPWCGHCKNLKPHWDQAASELR--GKVKLGALDA 288
+V+ LTD +F++ V K + LVEF+APWCGHCK L P +++ + + V + +D
Sbjct: 24 DVVVLTDDSFEKEVGKDKGA-LVEFYAPWCGHCKKLAPEYEKLGASFKKAKSVLIAKVDC 82
Query: 289 TVHNAVASRYGVQGYPTIKFFPAGVKTGEAQEYDGGRSSSDIVRWAS 429
+V ++YGV GYPTI++FP G + E Q+Y+G R++ + + +
Sbjct: 83 DEQKSVCTKYGVSGYPTIQWFPKG--SLEPQKYEGPRNAEALAEYVN 127
>sp|P54399|PDI_DROME Protein disulfide-isomerase precursor (PDI)
Length = 496
Score = 104 bits (260), Expect = 3e-22
Identities = 55/146 (37%), Positives = 86/146 (58%), Gaps = 3/146 (2%)
Frame = +1
Query: 118 VIELTDSNFDELVLKSEEPWLVEFFAPWCGHCKNLKPHWDQAASELRGK---VKLGALDA 288
V+ T NF +L+ +E LVEF+APWCGHCK L P + +AA +L K +KL +DA
Sbjct: 29 VLVATVDNFKQLIADNEFV-LVEFYAPWCGHCKALAPEYAKAAQQLAEKESPIKLAKVDA 87
Query: 289 TVHNAVASRYGVQGYPTIKFFPAGVKTGEAQEYDGGRSSSDIVRWASDKVVEQLPAPELK 468
TV +A +Y V+GYPT+KFF ++G EY GGR ++DI+ W + K P K
Sbjct: 88 TVEGELAEQYAVRGYPTLKFF----RSGSPVEYSGGRQAADIIAWVTKKT-----GPPAK 138
Query: 469 EITNQDVLKSTCEDHQLCVIAVLPNI 546
++T+ + +D+++ +I ++
Sbjct: 139 DLTSVADAEQFLKDNEIAIIGFFKDL 164
Score = 67.8 bits (164), Expect = 4e-11
Identities = 37/119 (31%), Positives = 66/119 (55%), Gaps = 4/119 (3%)
Frame = +1
Query: 127 LTDSNFDELVLKSEEPWLVEFFAPWCGHCKNLKPHWDQAASELRGK--VKLGALDATVHN 300
L SNF+ + L + LVEF+APWCGHCK L P +DQ A + + + + +D+T +
Sbjct: 372 LVSSNFESVALDKSKSVLVEFYAPWCGHCKQLAPIYDQLAEKYKDNEDIVIAKMDSTANE 431
Query: 301 AVASRYGVQGYPTIKFFPAGVKTGEAQEYDGGRSSSDIVRW--ASDKVVEQLPAPELKE 471
+ + + +PTIK+F + + +++ R+ D V++ A+ +V + P E +E
Sbjct: 432 LESIK--ISSFPTIKYFRK--EDNKVIDFNLDRTLDDFVKFLDANGEVADSEPVEETEE 486
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 95,710,863
Number of Sequences: 369166
Number of extensions: 1946293
Number of successful extensions: 6233
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 5701
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 6071
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 8438301375
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)