Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_019_H21
(758 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q15084|PDIA6_HUMAN Protein disulfide-isomerase A6 precur... 273 4e-73
sp|Q5R6T1|PDIA6_PONPY Protein disulfide-isomerase A6 precursor 273 4e-73
sp|Q11067|PDIA6_CAEEL Probable protein disulfide-isomerase ... 273 4e-73
sp|Q63081|PDIA6_RAT Protein disulfide-isomerase A6 precurso... 272 6e-73
sp|Q922R8|PDIA6_MOUSE Protein disulfide-isomerase A6 precur... 269 7e-72
sp|P38660|PDIA6_MESAU Protein disulfide-isomerase A6 precur... 268 2e-71
sp|O22263|PDIA6_ARATH Probable protein disulfide-isomerase ... 164 3e-40
sp|P38661|PDIA6_MEDSA Probable protein disulfide-isomerase ... 152 9e-37
sp|P34329|PDIA4_CAEEL Probable protein disulfide-isomerase ... 151 2e-36
sp|Q00216|TIGA_ASPNG Protein disulfide-isomerase tigA precu... 137 2e-32
>sp|Q15084|PDIA6_HUMAN Protein disulfide-isomerase A6 precursor (Protein disulfide
isomerase P5) (Thioredoxin domain-containing protein 7)
Length = 440
Score = 273 bits (698), Expect = 4e-73
Identities = 136/231 (58%), Positives = 163/231 (70%), Gaps = 5/231 (2%)
Frame = +3
Query: 69 LYSPSDDVIDLTPSNFN-DVKNGDELWFVEFYAPWCGHCQSLAPEWKKAASALKGVVKVG 245
LYS SDDVI+LTPSNFN +V D LW VEFYAPWCGHCQ L PEWKKAA+ALK VVKVG
Sbjct: 20 LYSSSDDVIELTPSNFNREVIQSDSLWLVEFYAPWCGHCQRLTPEWKKAATALKDVVKVG 79
Query: 246 AVDMDKYSSVGQPYNIQGFPTIKVFGKNKHSPKDYQGERNANAIVNNALKELEELVRSRL 425
AVD DK+ S+G Y +QGFPTIK+FG NK+ P+DYQG R AIV+ AL L +LV+ RL
Sbjct: 80 AVDADKHHSLGGQYGVQGFPTIKIFGSNKNRPEDYQGGRTGEAIVDAALSALRQLVKDRL 139
Query: 426 XXXXXXXXXXXXXXXXXXXXXXXXXEVIELTDSNFDELVLKSEEPWLVEFFAPWCGHCKN 605
+VIELTD +FD+ VL SE+ W+VEF+APWCGHCKN
Sbjct: 140 ----GGRSGGYSSGKQGRSDSSSKKDVIELTDDSFDKNVLDSEDVWMVEFYAPWCGHCKN 195
Query: 606 LKPHWDQAASEL----RGKVKLGALDATVHNAVASRYGVQGYPTIKFFPAG 746
L+P W AASE+ +GKVKL A+DATV+ +ASRYG++G+PTIK F G
Sbjct: 196 LEPEWAAAASEVKEQTKGKVKLAAVDATVNQVLASRYGIRGFPTIKIFQKG 246
Score = 103 bits (257), Expect = 5e-22
Identities = 54/111 (48%), Positives = 72/111 (64%), Gaps = 5/111 (4%)
Frame = +3
Query: 75 SPSDDVIDLTPSNFN-DVKNGDELWFVEFYAPWCGHCQSLAPEWKKAASALK----GVVK 239
S DVI+LT +F+ +V + +++W VEFYAPWCGHC++L PEW AAS +K G VK
Sbjct: 157 SSKKDVIELTDDSFDKNVLDSEDVWMVEFYAPWCGHCKNLEPEWAAAASEVKEQTKGKVK 216
Query: 240 VGAVDMDKYSSVGQPYNIQGFPTIKVFGKNKHSPKDYQGERNANAIVNNAL 392
+ AVD + Y I+GFPTIK+F K + SP DY G R + IV+ AL
Sbjct: 217 LAAVDATVNQVLASRYGIRGFPTIKIFQKGE-SPVDYDGGRTRSDIVSRAL 266
>sp|Q5R6T1|PDIA6_PONPY Protein disulfide-isomerase A6 precursor
Length = 440
Score = 273 bits (698), Expect = 4e-73
Identities = 136/231 (58%), Positives = 163/231 (70%), Gaps = 5/231 (2%)
Frame = +3
Query: 69 LYSPSDDVIDLTPSNFN-DVKNGDELWFVEFYAPWCGHCQSLAPEWKKAASALKGVVKVG 245
LYS SDDVI+LTPSNFN +V D LW VEFYAPWCGHCQ L PEWKKAA+ALK VVKVG
Sbjct: 20 LYSSSDDVIELTPSNFNREVIQSDSLWLVEFYAPWCGHCQRLTPEWKKAATALKDVVKVG 79
Query: 246 AVDMDKYSSVGQPYNIQGFPTIKVFGKNKHSPKDYQGERNANAIVNNALKELEELVRSRL 425
AVD DK+ S+G Y +QGFPTIK+FG NK+ P+DYQG R AIV+ AL L +LV+ RL
Sbjct: 80 AVDADKHHSLGGQYGVQGFPTIKIFGSNKNRPEDYQGGRTGEAIVDAALSALRQLVKDRL 139
Query: 426 XXXXXXXXXXXXXXXXXXXXXXXXXEVIELTDSNFDELVLKSEEPWLVEFFAPWCGHCKN 605
+VIELTD +FD+ VL SE+ W+VEF+APWCGHCKN
Sbjct: 140 ----GGQSGGYSSGKQGRSDSSSKKDVIELTDDSFDKNVLDSEDVWMVEFYAPWCGHCKN 195
Query: 606 LKPHWDQAASEL----RGKVKLGALDATVHNAVASRYGVQGYPTIKFFPAG 746
L+P W AASE+ +GKVKL A+DATV+ +ASRYG++G+PTIK F G
Sbjct: 196 LEPEWAAAASEVKEQTKGKVKLAAVDATVNQVLASRYGIRGFPTIKIFQKG 246
Score = 103 bits (257), Expect = 5e-22
Identities = 54/111 (48%), Positives = 72/111 (64%), Gaps = 5/111 (4%)
Frame = +3
Query: 75 SPSDDVIDLTPSNFN-DVKNGDELWFVEFYAPWCGHCQSLAPEWKKAASALK----GVVK 239
S DVI+LT +F+ +V + +++W VEFYAPWCGHC++L PEW AAS +K G VK
Sbjct: 157 SSKKDVIELTDDSFDKNVLDSEDVWMVEFYAPWCGHCKNLEPEWAAAASEVKEQTKGKVK 216
Query: 240 VGAVDMDKYSSVGQPYNIQGFPTIKVFGKNKHSPKDYQGERNANAIVNNAL 392
+ AVD + Y I+GFPTIK+F K + SP DY G R + IV+ AL
Sbjct: 217 LAAVDATVNQVLASRYGIRGFPTIKIFQKGE-SPVDYDGGRTRSDIVSRAL 266
>sp|Q11067|PDIA6_CAEEL Probable protein disulfide-isomerase A6 precursor
Length = 440
Score = 273 bits (698), Expect = 4e-73
Identities = 128/228 (56%), Positives = 165/228 (72%), Gaps = 2/228 (0%)
Frame = +3
Query: 69 LYSPSDDVIDLTPSNFND-VKNGDELWFVEFYAPWCGHCQSLAPEWKKAASALKGVVKVG 245
+YS DDV++LT +NF V N D++W VEFYAPWCGHC+SL PE+KKAASALKGV KVG
Sbjct: 19 MYSKKDDVVELTEANFQSKVINSDDIWIVEFYAPWCGHCKSLVPEYKKAASALKGVAKVG 78
Query: 246 AVDMDKYSSVGQPYNIQGFPTIKVFGKNKHSPKDYQGERNANAIVNNALKELEELVRSRL 425
AVDM ++ SVG PYN+QGFPT+K+FG +K P DY G+R A AI ++ L E ++ V +RL
Sbjct: 79 AVDMTQHQSVGGPYNVQGFPTLKIFGADKKKPTDYNGQRTAQAIADSVLAEAKKAVSARL 138
Query: 426 -XXXXXXXXXXXXXXXXXXXXXXXXXEVIELTDSNFDELVLKSEEPWLVEFFAPWCGHCK 602
EV+ELTD+NF++LVL S++ WLVEFFAPWCGHCK
Sbjct: 139 GGKSSGSSSSGSGSGSGKRGGGGSGNEVVELTDANFEDLVLNSKDIWLVEFFAPWCGHCK 198
Query: 603 NLKPHWDQAASELRGKVKLGALDATVHNAVASRYGVQGYPTIKFFPAG 746
+L+P W AASEL+GKV+LGALDATVH VA+++ ++G+PTIK+F G
Sbjct: 199 SLEPQWKAAASELKGKVRLGALDATVHTVVANKFAIRGFPTIKYFAPG 246
Score = 104 bits (260), Expect = 2e-22
Identities = 44/84 (52%), Positives = 62/84 (73%)
Frame = +3
Query: 501 EVIELTDSNFDELVLKSEEPWLVEFFAPWCGHCKNLKPHWDQAASELRGKVKLGALDATV 680
+V+ELT++NF V+ S++ W+VEF+APWCGHCK+L P + +AAS L+G K+GA+D T
Sbjct: 25 DVVELTEANFQSKVINSDDIWIVEFYAPWCGHCKSLVPEYKKAASALKGVAKVGAVDMTQ 84
Query: 681 HNAVASRYGVQGYPTIKFFPAGVK 752
H +V Y VQG+PT+K F A K
Sbjct: 85 HQSVGGPYNVQGFPTLKIFGADKK 108
>sp|Q63081|PDIA6_RAT Protein disulfide-isomerase A6 precursor (Protein disulfide
isomerase P5) (Calcium-binding protein 1) (CaBP1)
(Thioredoxin domain-containing protein 7)
Length = 440
Score = 272 bits (696), Expect = 6e-73
Identities = 135/232 (58%), Positives = 163/232 (70%), Gaps = 5/232 (2%)
Frame = +3
Query: 66 ALYSPSDDVIDLTPSNFN-DVKNGDELWFVEFYAPWCGHCQSLAPEWKKAASALKGVVKV 242
ALYS SDDVI+LTPSNFN +V D LW VEFYAPWCGHCQ L PEWKKAASALK VVKV
Sbjct: 19 ALYSSSDDVIELTPSNFNREVIQSDSLWLVEFYAPWCGHCQRLTPEWKKAASALKDVVKV 78
Query: 243 GAVDMDKYSSVGQPYNIQGFPTIKVFGKNKHSPKDYQGERNANAIVNNALKELEELVRSR 422
GAV+ DK+ S+G Y +QGFPTIK+FG NK+ P+DYQG R AIV+ AL L +LV+ R
Sbjct: 79 GAVNADKHQSLGGQYGVQGFPTIKIFGANKNKPEDYQGGRTGEAIVDAALSALRQLVKDR 138
Query: 423 LXXXXXXXXXXXXXXXXXXXXXXXXXEVIELTDSNFDELVLKSEEPWLVEFFAPWCGHCK 602
L +V+ELTD FD+ VL SE+ W+VEF+APWCGHCK
Sbjct: 139 L----GGRSGGYSSGKQGRGDSSSKKDVVELTDDTFDKNVLDSEDVWMVEFYAPWCGHCK 194
Query: 603 NLKPHWDQAASEL----RGKVKLGALDATVHNAVASRYGVQGYPTIKFFPAG 746
NL+P W AA+E+ +GKVKL A+DATV+ +ASRYG++G+PTIK F G
Sbjct: 195 NLEPEWAAAATEVKEQTKGKVKLAAVDATVNQVLASRYGIKGFPTIKIFQKG 246
Score = 101 bits (252), Expect = 2e-21
Identities = 52/111 (46%), Positives = 71/111 (63%), Gaps = 5/111 (4%)
Frame = +3
Query: 75 SPSDDVIDLTPSNFN-DVKNGDELWFVEFYAPWCGHCQSLAPEWKKAASALK----GVVK 239
S DV++LT F+ +V + +++W VEFYAPWCGHC++L PEW AA+ +K G VK
Sbjct: 157 SSKKDVVELTDDTFDKNVLDSEDVWMVEFYAPWCGHCKNLEPEWAAAATEVKEQTKGKVK 216
Query: 240 VGAVDMDKYSSVGQPYNIQGFPTIKVFGKNKHSPKDYQGERNANAIVNNAL 392
+ AVD + Y I+GFPTIK+F K + SP DY G R + IV+ AL
Sbjct: 217 LAAVDATVNQVLASRYGIKGFPTIKIFQKGE-SPVDYDGGRTRSDIVSRAL 266
>sp|Q922R8|PDIA6_MOUSE Protein disulfide-isomerase A6 precursor (Thioredoxin
domain-containing protein 7)
Length = 440
Score = 269 bits (687), Expect = 7e-72
Identities = 133/231 (57%), Positives = 162/231 (70%), Gaps = 5/231 (2%)
Frame = +3
Query: 69 LYSPSDDVIDLTPSNFN-DVKNGDELWFVEFYAPWCGHCQSLAPEWKKAASALKGVVKVG 245
LYS SDDVI+LTPSNFN +V D LW VEFYAPWCGHCQ L PEWKKAA+ALK VVKVG
Sbjct: 20 LYSSSDDVIELTPSNFNREVIQSDGLWLVEFYAPWCGHCQRLTPEWKKAATALKDVVKVG 79
Query: 246 AVDMDKYSSVGQPYNIQGFPTIKVFGKNKHSPKDYQGERNANAIVNNALKELEELVRSRL 425
AV+ DK+ S+G Y +QGFPTIK+FG NK+ P+DYQG R AIV+ AL L +LV+ RL
Sbjct: 80 AVNADKHQSLGGQYGVQGFPTIKIFGANKNKPEDYQGGRTGEAIVDAALSALRQLVKDRL 139
Query: 426 XXXXXXXXXXXXXXXXXXXXXXXXXEVIELTDSNFDELVLKSEEPWLVEFFAPWCGHCKN 605
+V+ELTD FD+ VL SE+ W+VEF+APWCGHCKN
Sbjct: 140 ----GGRSGGYSSGKQGRGDSSSKKDVVELTDDTFDKNVLDSEDVWMVEFYAPWCGHCKN 195
Query: 606 LKPHWDQAASEL----RGKVKLGALDATVHNAVASRYGVQGYPTIKFFPAG 746
L+P W AA+E+ +GKVKL A+DATV+ +ASRYG++G+PTIK F G
Sbjct: 196 LEPEWAAAATEVKEQTKGKVKLAAVDATVNQVLASRYGIKGFPTIKIFQKG 246
Score = 101 bits (252), Expect = 2e-21
Identities = 52/111 (46%), Positives = 71/111 (63%), Gaps = 5/111 (4%)
Frame = +3
Query: 75 SPSDDVIDLTPSNFN-DVKNGDELWFVEFYAPWCGHCQSLAPEWKKAASALK----GVVK 239
S DV++LT F+ +V + +++W VEFYAPWCGHC++L PEW AA+ +K G VK
Sbjct: 157 SSKKDVVELTDDTFDKNVLDSEDVWMVEFYAPWCGHCKNLEPEWAAAATEVKEQTKGKVK 216
Query: 240 VGAVDMDKYSSVGQPYNIQGFPTIKVFGKNKHSPKDYQGERNANAIVNNAL 392
+ AVD + Y I+GFPTIK+F K + SP DY G R + IV+ AL
Sbjct: 217 LAAVDATVNQVLASRYGIKGFPTIKIFQKGE-SPVDYDGGRTRSDIVSRAL 266
>sp|P38660|PDIA6_MESAU Protein disulfide-isomerase A6 precursor (Protein disulfide
isomerase P5)
Length = 439
Score = 268 bits (684), Expect = 2e-71
Identities = 132/231 (57%), Positives = 162/231 (70%), Gaps = 5/231 (2%)
Frame = +3
Query: 69 LYSPSDDVIDLTPSNFN-DVKNGDELWFVEFYAPWCGHCQSLAPEWKKAASALKGVVKVG 245
LYS SDDVI+LTPSNFN +V + LW VEFYAPWCGHCQ L PEWKKAA+ALK VVKVG
Sbjct: 20 LYSSSDDVIELTPSNFNREVIQSNSLWLVEFYAPWCGHCQRLTPEWKKAATALKDVVKVG 79
Query: 246 AVDMDKYSSVGQPYNIQGFPTIKVFGKNKHSPKDYQGERNANAIVNNALKELEELVRSRL 425
AVD DK+ S+G Y +QGFPTIK+FG NK+ P+DYQG R AIV+ AL L +LV+ RL
Sbjct: 80 AVDADKHQSLGGQYGVQGFPTIKIFGANKNKPEDYQGGRTGEAIVDAALSALRQLVKDRL 139
Query: 426 XXXXXXXXXXXXXXXXXXXXXXXXXEVIELTDSNFDELVLKSEEPWLVEFFAPWCGHCKN 605
+VIELTD FD+ VL S++ W+VEF+APWCGHCKN
Sbjct: 140 ----SGRSGGYSSGKQGRGDSSSKKDVIELTDDTFDKNVLDSDDVWMVEFYAPWCGHCKN 195
Query: 606 LKPHWDQAASEL----RGKVKLGALDATVHNAVASRYGVQGYPTIKFFPAG 746
L+P W AA+E+ +GKVKL A+DATV+ +A+RYG++G+PTIK F G
Sbjct: 196 LEPEWATAATEVKEQTKGKVKLAAVDATVNQVLANRYGIRGFPTIKIFQKG 246
Score = 102 bits (254), Expect = 1e-21
Identities = 53/111 (47%), Positives = 71/111 (63%), Gaps = 5/111 (4%)
Frame = +3
Query: 75 SPSDDVIDLTPSNFN-DVKNGDELWFVEFYAPWCGHCQSLAPEWKKAASALK----GVVK 239
S DVI+LT F+ +V + D++W VEFYAPWCGHC++L PEW AA+ +K G VK
Sbjct: 157 SSKKDVIELTDDTFDKNVLDSDDVWMVEFYAPWCGHCKNLEPEWATAATEVKEQTKGKVK 216
Query: 240 VGAVDMDKYSSVGQPYNIQGFPTIKVFGKNKHSPKDYQGERNANAIVNNAL 392
+ AVD + Y I+GFPTIK+F K + +P DY G R + IV+ AL
Sbjct: 217 LAAVDATVNQVLANRYGIRGFPTIKIFQKGE-APVDYDGGRTRSDIVSRAL 266
>sp|O22263|PDIA6_ARATH Probable protein disulfide-isomerase A6 precursor (P5)
Length = 361
Score = 164 bits (414), Expect = 3e-40
Identities = 89/230 (38%), Positives = 123/230 (53%), Gaps = 4/230 (1%)
Frame = +3
Query: 81 SDDVIDLTPSNFNDVKNGDELWFVEFYAPWCGHCQSLAPEWKKAASALKGV--VKVGAVD 254
+DDV+ LT +F D+ VEFYAPWCGHC+ LAPE++K ++ K V + VD
Sbjct: 22 ADDVVVLTDDSFEKEVGKDKGALVEFYAPWCGHCKKLAPEYEKLGASFKKAKSVLIAKVD 81
Query: 255 MDKYSSVGQPYNIQGFPTIKVFGKNKHSPKDYQGERNANAIVNNALKELEELVRSRLXXX 434
D+ SV Y + G+PTI+ F K P+ Y+G RNA A+ KE V+
Sbjct: 82 CDEQKSVCTKYGVSGYPTIQWFPKGSLEPQKYEGPRNAEALAEYVNKEGGTNVK------ 135
Query: 435 XXXXXXXXXXXXXXXXXXXXXXEVIELTDSNFDELVLKSEEPWLVEFFAPWCGHCKNLKP 614
V+ LT NFDE+VL + LVEF+APWCGHCK+L P
Sbjct: 136 ----------------LAAVPQNVVVLTPDNFDEIVLDQNKDVLVEFYAPWCGHCKSLAP 179
Query: 615 HWDQAASELRGK--VKLGALDATVHNAVASRYGVQGYPTIKFFPAGVKTG 758
+++ A+ + + V + LDA H A+ +YGV G+PT+KFFP K G
Sbjct: 180 TYEKVATVFKQEEGVVIANLDADAHKALGEKYGVSGFPTLKFFPKDNKAG 229
Score = 90.1 bits (222), Expect = 6e-18
Identities = 46/105 (43%), Positives = 69/105 (65%), Gaps = 6/105 (5%)
Frame = +3
Query: 87 DVIDLTPSNFNDV---KNGDELWFVEFYAPWCGHCQSLAPEWKKAASALK---GVVKVGA 248
+V+ LTP NF+++ +N D L VEFYAPWCGHC+SLAP ++K A+ K GVV +
Sbjct: 142 NVVVLTPDNFDEIVLDQNKDVL--VEFYAPWCGHCKSLAPTYEKVATVFKQEEGVV-IAN 198
Query: 249 VDMDKYSSVGQPYNIQGFPTIKVFGKNKHSPKDYQGERNANAIVN 383
+D D + ++G+ Y + GFPT+K F K+ + DY G R+ + V+
Sbjct: 199 LDADAHKALGEKYGVSGFPTLKFFPKDNKAGHDYDGGRDLDDFVS 243
>sp|P38661|PDIA6_MEDSA Probable protein disulfide-isomerase A6 precursor (P5)
Length = 364
Score = 152 bits (384), Expect = 9e-37
Identities = 85/230 (36%), Positives = 121/230 (52%), Gaps = 4/230 (1%)
Frame = +3
Query: 81 SDDVIDLTPSNFNDVKNGDELWFVEFYAPWCGHCQSLAPEWKKAASALKGV--VKVGAVD 254
+DDV+ LT NF D+ VEFYAPWCGHC+ LAPE++K ++ K V + VD
Sbjct: 28 ADDVVVLTEENFEKEVGHDKGALVEFYAPWCGHCKKLAPEYEKLPNSFKKAKSVLIAKVD 87
Query: 255 MDKYSSVGQPYNIQGFPTIKVFGKNKHSPKDYQGERNANAIVNNALKELEELVRSRLXXX 434
D++ SV Y + G+PTI+ F K PK ++G R A + L E V +
Sbjct: 88 CDEHKSVCSKYGVSGYPTIQWFPKGSLEPKKFEGPRTA--------ESLAEFVNTE---- 135
Query: 435 XXXXXXXXXXXXXXXXXXXXXXEVIELTDSNFDELVLKSEEPWLVEFFAPWCGHCKNLKP 614
V+ LT F+E+VL + LVEF+APWCGHCK+L P
Sbjct: 136 ----------GGTNVKIATAPSHVVVLTPETFNEVVLDGTKDVLVEFYAPWCGHCKSLAP 185
Query: 615 HWDQAASELRGK--VKLGALDATVHNAVASRYGVQGYPTIKFFPAGVKTG 758
+++ A+ + + V + LDA + +A +Y V G+PT+KFFP G K G
Sbjct: 186 IYEKVAAVFKSEDDVVIANLDADKYRDLAEKYDVSGFPTLKFFPKGNKAG 235
Score = 89.4 bits (220), Expect = 1e-17
Identities = 44/100 (44%), Positives = 63/100 (63%), Gaps = 3/100 (3%)
Frame = +3
Query: 90 VIDLTPSNFNDVK-NGDELWFVEFYAPWCGHCQSLAPEWKKAASALKGV--VKVGAVDMD 260
V+ LTP FN+V +G + VEFYAPWCGHC+SLAP ++K A+ K V + +D D
Sbjct: 149 VVVLTPETFNEVVLDGTKDVLVEFYAPWCGHCKSLAPIYEKVAAVFKSEDDVVIANLDAD 208
Query: 261 KYSSVGQPYNIQGFPTIKVFGKNKHSPKDYQGERNANAIV 380
KY + + Y++ GFPT+K F K + +DY G R+ + V
Sbjct: 209 KYRDLAEKYDVSGFPTLKFFPKGNKAGEDYGGGRDLDDFV 248
>sp|P34329|PDIA4_CAEEL Probable protein disulfide-isomerase A4 precursor (ERp-72 homolog)
Length = 618
Score = 151 bits (382), Expect = 2e-36
Identities = 89/231 (38%), Positives = 125/231 (54%), Gaps = 3/231 (1%)
Frame = +3
Query: 63 EALYSPSDDVIDLTPSNFNDVKNGDELWFVEFYAPWCGHCQSLAPEWKKAASALKGVVKV 242
E Y + V+ LT NF+ + V+FYAPWCGHC+ LAPE++KA+S K + +
Sbjct: 29 ELNYEMDEGVVVLTDKNFDAFLKKNPSVLVKFYAPWCGHCKHLAPEYEKASS--KVSIPL 86
Query: 243 GAVDMDKYSSVGQPYNIQGFPTIKVFGKNKHSPKDYQGERNANAIVNNALKELEELVRSR 422
VD + +G+ + IQG+PT+K F K+ P DY G R+ IV E V SR
Sbjct: 87 AKVDATVETELGKRFEIQGYPTLK-FWKDGKGPNDYDGGRDEAGIV--------EWVESR 137
Query: 423 LXXXXXXXXXXXXXXXXXXXXXXXXXEVIELTDSNFDELVLKSEEPWLVEFFAPWCGHCK 602
+ EV+ LT NFD+ + + E LVEF+APWCGHCK
Sbjct: 138 V----------------DPNYKPPPEEVVTLTTENFDDFI-SNNELVLVEFYAPWCGHCK 180
Query: 603 NLKPHWDQAASELR---GKVKLGALDATVHNAVASRYGVQGYPTIKFFPAG 746
L P +++AA +L+ KVKLG +DAT+ + ++YGV GYPT+K G
Sbjct: 181 KLAPEYEKAAQKLKAQGSKVKLGKVDATIEKDLGTKYGVSGYPTMKIIRNG 231
Score = 94.0 bits (232), Expect = 4e-19
Identities = 46/104 (44%), Positives = 63/104 (60%), Gaps = 3/104 (2%)
Frame = +3
Query: 78 PSDDVIDLTPSNFNDVKNGDELWFVEFYAPWCGHCQSLAPEWKKAASALK---GVVKVGA 248
P ++V+ LT NF+D + +EL VEFYAPWCGHC+ LAPE++KAA LK VK+G
Sbjct: 145 PPEEVVTLTTENFDDFISNNELVLVEFYAPWCGHCKKLAPEYEKAAQKLKAQGSKVKLGK 204
Query: 249 VDMDKYSSVGQPYNIQGFPTIKVFGKNKHSPKDYQGERNANAIV 380
VD +G Y + G+PT+K+ + DY G R A I+
Sbjct: 205 VDATIEKDLGTKYGVSGYPTMKIIRNGRRF--DYNGpreAAGII 246
Score = 72.0 bits (175), Expect = 2e-12
Identities = 35/81 (43%), Positives = 54/81 (66%), Gaps = 3/81 (3%)
Frame = +3
Query: 522 SNFDELVLKSEEPWLVEFFAPWCGHCKNLKPHW---DQAASELRGKVKLGALDATVHNAV 692
SNFD++V + L+EF+APWCGHCK+ + + QA + + V L +DAT+++A
Sbjct: 507 SNFDKIVNDESKDVLIEFYAPWCGHCKSFESKYVELAQALKKTQPNVVLAKMDATINDA- 565
Query: 693 ASRYGVQGYPTIKFFPAGVKT 755
S++ V+G+PTI F PAG K+
Sbjct: 566 PSQFAVEGFPTIYFAPAGKKS 586
Score = 54.7 bits (130), Expect = 3e-07
Identities = 37/104 (35%), Positives = 52/104 (50%), Gaps = 7/104 (6%)
Frame = +3
Query: 75 SPSDD---VIDLTPSNFNDVKNGDEL-WFVEFYAPWCGHCQSLAPEWKKAASALKGV-VK 239
+P DD V + SNF+ + N + +EFYAPWCGHC+S ++ + A ALK
Sbjct: 493 APKDDKGPVKTVVGSNFDKIVNDESKDVLIEFYAPWCGHCKSFESKYVELAQALKKTQPN 552
Query: 240 VGAVDMD-KYSSVGQPYNIQGFPTIKVFGKNKHS-PKDYQGERN 365
V MD + + ++GFPTI K S P Y G R+
Sbjct: 553 VVLAKMDATINDAPSQFAVEGFPTIYFAPAGKKSEPIKYSGNRD 596
>sp|Q00216|TIGA_ASPNG Protein disulfide-isomerase tigA precursor
Length = 359
Score = 137 bits (346), Expect = 2e-32
Identities = 85/228 (37%), Positives = 115/228 (50%), Gaps = 9/228 (3%)
Frame = +3
Query: 90 VIDLTPSNFNDV--KNGDELWFVEFYAPWCGHCQSLAPEWKKAASALKGV---VKVGAVD 254
V+DL P NF+DV K+G VEF+APWCGHC++LAP +++ A V VG VD
Sbjct: 21 VVDLVPKNFDDVVLKSGKPA-LVEFFAPWCGHCKNLAPVYEELGQAFAHASDKVTVGKVD 79
Query: 255 MDKYSSVGQPYNIQGFPTIKVFGKNKHSPKDYQGERNANAIVNNALKELEELVRSRLXXX 434
D++ +G+ + +QGFPT+K F P+DY+G R+ L+ L + +
Sbjct: 80 ADEHRDLGRKFGVQGFPTLKWFDGKSDEPEDYKGGRD--------LESLSSFISEK---- 127
Query: 435 XXXXXXXXXXXXXXXXXXXXXXEVIELTDSNFDELVLKSEEPWLVEFFAPWCGHCKNLKP 614
+V L D+ F V + LV F APWCGHCKNL P
Sbjct: 128 ---------TGVKPRGPKKEPSKVEMLNDATFKGAV-GGDNDVLVAFTAPWCGHCKNLAP 177
Query: 615 HWDQAASE--LRGKVKLGALDATVHN--AVASRYGVQGYPTIKFFPAG 746
W+ A++ L V + +DA N A A GV GYPTIKFFP G
Sbjct: 178 TWEALANDFVLEPNVVIAKVDADAENGKATAREQGVSGYPTIKFFPKG 225
Score = 65.1 bits (157), Expect = 2e-10
Identities = 34/99 (34%), Positives = 50/99 (50%), Gaps = 4/99 (4%)
Frame = +3
Query: 99 LTPSNFNDVKNGDELWFVEFYAPWCGHCQSLAPEWKKAAS--ALKGVVKVGAVDMDKYS- 269
L + F GD V F APWCGHC++LAP W+ A+ L+ V + VD D +
Sbjct: 145 LNDATFKGAVGGDNDVLVAFTAPWCGHCKNLAPTWEALANDFVLEPNVVIAKVDADAENG 204
Query: 270 -SVGQPYNIQGFPTIKVFGKNKHSPKDYQGERNANAIVN 383
+ + + G+PTIK F K Y+G R+ A ++
Sbjct: 205 KATAREQGVSGYPTIKFFPKGSTESVPYEGARSEQAFID 243
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 73,114,222
Number of Sequences: 369166
Number of extensions: 1293632
Number of successful extensions: 4520
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3787
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4259
length of database: 68,354,980
effective HSP length: 108
effective length of database: 48,403,600
effective search space used: 6970118400
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)