Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_002_P02
(707 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q922R8|PDIA6_MOUSE Protein disulfide-isomerase A6 precur... 225 1e-58
sp|Q11067|PDIA6_CAEEL Probable protein disulfide-isomerase ... 224 2e-58
sp|Q63081|PDIA6_RAT Protein disulfide-isomerase A6 precurso... 223 5e-58
sp|Q15084|PDIA6_HUMAN Protein disulfide-isomerase A6 precur... 218 1e-56
sp|Q5R6T1|PDIA6_PONPY Protein disulfide-isomerase A6 precursor 215 8e-56
sp|P38660|PDIA6_MESAU Protein disulfide-isomerase A6 precur... 215 1e-55
sp|P75168|PT1_MYCPN Phosphoenolpyruvate-protein phosphotran... 39 0.014
sp|P54399|PDI_DROME Protein disulfide-isomerase precursor (... 35 0.20
sp|Q17770|PDI2_CAEEL Protein disulfide-isomerase 2 precurso... 33 0.57
sp|P47668|PT1_MYCGE Phosphoenolpyruvate-protein phosphotran... 32 2.2
>sp|Q922R8|PDIA6_MOUSE Protein disulfide-isomerase A6 precursor (Thioredoxin
domain-containing protein 7)
Length = 440
Score = 225 bits (573), Expect = 1e-58
Identities = 106/190 (55%), Positives = 137/190 (72%), Gaps = 1/190 (0%)
Frame = +3
Query: 24 EYDGGRSSSDIVRWASDKVVEQLPAPELKEITNQDVLKSTCEDHQLCVIAVLPNILDCQS 203
+YDGGR+ SDIV A D + P PEL EI N+D+ K TCE+HQLCV+AVLP+ILD +
Sbjct: 251 DYDGGRTRSDIVSRALDLFSDNAPPPELLEIINEDIAKKTCEEHQLCVVAVLPHILDTGA 310
Query: 204 ACRNSYLDTIRVSSDKYKANRWGWCWTEAMKLPAIEKAFGIGGFGYPALVVVNVRKMKYA 383
A RNSYL+ + +DKYK WGW WTEA +E A GIGGFGYPA+ +N RKMK+A
Sbjct: 311 AGRNSYLEVLLKLADKYKKKMWGWLWTEAGAQYELENALGIGGFGYPAMAAINARKMKFA 370
Query: 384 TLTGPFSQTGIQDFVRDVSLGRGSTAAIVGEGLPAITPVDPWDGKDGEMPKEEEIDLSEL 563
L G FS+ GI +F+R++S GRGSTA + G P ITP +PWDGKDGE+P E++IDLS++
Sbjct: 371 LLKGSFSEQGINEFLRELSFGRGSTAPVGGGSFPTITprePWDGKDGELPVEDDIDLSDV 430
Query: 564 GIEE-PKSEL 590
+++ K EL
Sbjct: 431 ELDDLEKDEL 440
>sp|Q11067|PDIA6_CAEEL Probable protein disulfide-isomerase A6 precursor
Length = 440
Score = 224 bits (570), Expect = 2e-58
Identities = 99/192 (51%), Positives = 139/192 (72%)
Frame = +3
Query: 15 EAQEYDGGRSSSDIVRWASDKVVEQLPAPELKEITNQDVLKSTCEDHQLCVIAVLPNILD 194
+AQ+YDGGR SSDIV WAS + E +PAPE+ E NQ V++ C++ QLC+ A LP+ILD
Sbjct: 251 DAQDYDGGRQSSDIVAWASARAQENMPAPEVFEGINQQVVEDACKEKQLCIFAFLPHILD 310
Query: 195 CQSACRNSYLDTIRVSSDKYKANRWGWCWTEAMKLPAIEKAFGIGGFGYPALVVVNVRKM 374
CQS CRN+YL ++ S+K+K N WGW W E PA+E++F +GGFGYPA+ +N RK
Sbjct: 311 CQSECRNNYLAMLKEQSEKFKKNLWGWIWVEGAAQPALEESFEVGGFGYPAMTALNFRKN 370
Query: 375 KYATLTGPFSQTGIQDFVRDVSLGRGSTAAIVGEGLPAITPVDPWDGKDGEMPKEEEIDL 554
KYA L G F + GI +F+RD+S G+G T+++ G+G P I + WDGKDG +P E++IDL
Sbjct: 371 KYAVLKGSFGKDGIHEFLRDLSYGKGRTSSLRGDGFPKIQKTEKWDGKDGALPAEDDIDL 430
Query: 555 SELGIEEPKSEL 590
S++ ++ K+EL
Sbjct: 431 SDIDLD--KTEL 440
>sp|Q63081|PDIA6_RAT Protein disulfide-isomerase A6 precursor (Protein disulfide
isomerase P5) (Calcium-binding protein 1) (CaBP1)
(Thioredoxin domain-containing protein 7)
Length = 440
Score = 223 bits (567), Expect = 5e-58
Identities = 105/190 (55%), Positives = 136/190 (71%), Gaps = 1/190 (0%)
Frame = +3
Query: 24 EYDGGRSSSDIVRWASDKVVEQLPAPELKEITNQDVLKSTCEDHQLCVIAVLPNILDCQS 203
+YDGGR+ SDIV A D + P PEL EI N+D+ K TCE+HQLCV+AVLP+ILD +
Sbjct: 251 DYDGGRTRSDIVSRALDLFSDNAPPPELLEIINEDIAKKTCEEHQLCVVAVLPHILDTGA 310
Query: 204 ACRNSYLDTIRVSSDKYKANRWGWCWTEAMKLPAIEKAFGIGGFGYPALVVVNVRKMKYA 383
RNSYL+ + +DKYK WGW WTEA +E A GIGGFGYPA+ +N RKMK+A
Sbjct: 311 TGRNSYLEVLLKLADKYKKKMWGWLWTEAGAQYELENALGIGGFGYPAMAAINARKMKFA 370
Query: 384 TLTGPFSQTGIQDFVRDVSLGRGSTAAIVGEGLPAITPVDPWDGKDGEMPKEEEIDLSEL 563
L G FS+ GI +F+R++S GRGSTA + G P ITP +PWDGKDGE+P E++IDLS++
Sbjct: 371 LLKGSFSEQGINEFLRELSFGRGSTAPVGGGSFPNITprePWDGKDGELPVEDDIDLSDV 430
Query: 564 GIEE-PKSEL 590
+++ K EL
Sbjct: 431 ELDDLEKDEL 440
>sp|Q15084|PDIA6_HUMAN Protein disulfide-isomerase A6 precursor (Protein disulfide
isomerase P5) (Thioredoxin domain-containing protein 7)
Length = 440
Score = 218 bits (556), Expect = 1e-56
Identities = 100/184 (54%), Positives = 132/184 (71%)
Frame = +3
Query: 24 EYDGGRSSSDIVRWASDKVVEQLPAPELKEITNQDVLKSTCEDHQLCVIAVLPNILDCQS 203
+YDGGR+ SDIV A D + P PEL EI N+D+ K TCE+HQLCV+AVLP+ILD +
Sbjct: 251 DYDGGRTRSDIVSRALDLFSDNAPPPELLEIINEDIAKRTCEEHQLCVVAVLPHILDTGA 310
Query: 204 ACRNSYLDTIRVSSDKYKANRWGWCWTEAMKLPAIEKAFGIGGFGYPALVVVNVRKMKYA 383
A RNSYL+ + +DKYK WGW WTEA +E A GIGGFGYPA+ +N RKMK+A
Sbjct: 311 AGRNSYLEVLLKLADKYKKKMWGWLWTEAGAQSELETALGIGGFGYPAMAAINARKMKFA 370
Query: 384 TLTGPFSQTGIQDFVRDVSLGRGSTAAIVGEGLPAITPVDPWDGKDGEMPKEEEIDLSEL 563
L G FS+ GI +F+R++S GRGSTA + G P I +PWDG+DGE+P E++IDLS++
Sbjct: 371 LLKGSFSEQGINEFLRELSFGRGSTAPVGGGAFPTIVEREPWDGRDGELPVEDDIDLSDV 430
Query: 564 GIEE 575
+++
Sbjct: 431 ELDD 434
>sp|Q5R6T1|PDIA6_PONPY Protein disulfide-isomerase A6 precursor
Length = 440
Score = 215 bits (548), Expect = 8e-56
Identities = 98/184 (53%), Positives = 132/184 (71%)
Frame = +3
Query: 24 EYDGGRSSSDIVRWASDKVVEQLPAPELKEITNQDVLKSTCEDHQLCVIAVLPNILDCQS 203
+YDGGR+ SDIV A D + P PEL EI ++D+ K TCE+HQLCV++VLP+ILD +
Sbjct: 251 DYDGGRTRSDIVSRALDLFSDNAPPPELLEIISEDIAKRTCEEHQLCVVSVLPHILDTGA 310
Query: 204 ACRNSYLDTIRVSSDKYKANRWGWCWTEAMKLPAIEKAFGIGGFGYPALVVVNVRKMKYA 383
A RNSYL+ + +DKYK WGW WTEA +E A GIGGFGYPA+ +N RKMK+A
Sbjct: 311 AGRNSYLEVLLKLADKYKKKMWGWLWTEAGAQSELETALGIGGFGYPAMAAINARKMKFA 370
Query: 384 TLTGPFSQTGIQDFVRDVSLGRGSTAAIVGEGLPAITPVDPWDGKDGEMPKEEEIDLSEL 563
L G FS+ GI +F+R++S GRGSTA + G P I +PWDG+DGE+P E++IDLS++
Sbjct: 371 LLKGSFSEQGINEFLRELSFGRGSTAPVGGGAFPTIVEREPWDGRDGELPVEDDIDLSDV 430
Query: 564 GIEE 575
+++
Sbjct: 431 ELDD 434
>sp|P38660|PDIA6_MESAU Protein disulfide-isomerase A6 precursor (Protein disulfide
isomerase P5)
Length = 439
Score = 215 bits (547), Expect = 1e-55
Identities = 107/195 (54%), Positives = 137/195 (70%), Gaps = 2/195 (1%)
Frame = +3
Query: 12 GEAQ-EYDGGRSSSDIVRWASDKVVEQLPAPELKEITNQDVLKSTCEDHQLCVIAVLPNI 188
GEA +YDGGR+ SDIV A D + P PEL EI N+DV K CE+HQLCV+AVLP+I
Sbjct: 246 GEAPVDYDGGRTRSDIVSRALDLFSDNAPPPELLEIINEDVAKKMCEEHQLCVVAVLPHI 305
Query: 189 LDCQSACRNSYLDTIRVSSDKYKANRWGWCWTEAMKLPAIEKAFGIGGFGYPALVVVNVR 368
LD A RNSYL+ + +DKYK WGW WTEA +E A GIGGFGYPA+ +N R
Sbjct: 306 LDT-GAARNSYLEILLKLADKYKKKMWGWLWTEAGAQSELENALGIGGFGYPAMARINAR 364
Query: 369 KMKYATLTGPFSQTGIQDFVRDVSLGRGSTAAIVGEGLPAITPVDPWDGKDGEMPKEEEI 548
KMK+A L G FS+ GI +F+R++S GR STA + G PAIT +PWDG+DGE+P E++I
Sbjct: 365 KMKFALLKGSFSEQGINEFLRELSFGRASTAPVGGGSFPAITAREPWDGRDGELPVEDDI 424
Query: 549 DLSELGIEE-PKSEL 590
DLS++ +++ K EL
Sbjct: 425 DLSDVELDDLEKDEL 439
>sp|P75168|PT1_MYCPN Phosphoenolpyruvate-protein phosphotransferase (Phosphotransferase
system, enzyme I)
Length = 572
Score = 38.9 bits (89), Expect = 0.014
Identities = 23/77 (29%), Positives = 38/77 (49%), Gaps = 7/77 (9%)
Frame = +3
Query: 3 VKTGEAQEYDGGR-------SSSDIVRWASDKVVEQLPAPELKEITNQDVLKSTCEDHQL 161
VK G+ DG + +S D W K +E+ ELK+ TN++ + T + H +
Sbjct: 213 VKDGQIVGVDGRKGIAGLDLNSKDTTEWKKQKALEEKYQQELKQYTNKETV--TLDGHAV 270
Query: 162 CVIAVLPNILDCQSACR 212
V A + N+ D + AC+
Sbjct: 271 VVAANIGNVKDMELACQ 287
>sp|P54399|PDI_DROME Protein disulfide-isomerase precursor (PDI)
Length = 496
Score = 35.0 bits (79), Expect = 0.20
Identities = 15/61 (24%), Positives = 32/61 (52%)
Frame = +3
Query: 6 KTGEAQEYDGGRSSSDIVRWASDKVVEQLPAPELKEITNQDVLKSTCEDHQLCVIAVLPN 185
++G EY GGR ++DI+ W + K P K++T+ + +D+++ +I +
Sbjct: 109 RSGSPVEYSGGRQAADIIAWVTKKT-----GPPAKDLTSVADAEQFLKDNEIAIIGFFKD 163
Query: 186 I 188
+
Sbjct: 164 L 164
>sp|Q17770|PDI2_CAEEL Protein disulfide-isomerase 2 precursor (PDI 1) (Prolyl
4-hydroxylase beta subunit)
Length = 493
Score = 33.5 bits (75), Expect = 0.57
Identities = 17/55 (30%), Positives = 25/55 (45%)
Frame = +3
Query: 6 KTGEAQEYDGGRSSSDIVRWASDKVVEQLPAPELKEITNQDVLKSTCEDHQLCVI 170
+ G+ QEY+GGR I+ W K P K + + D +K E + VI
Sbjct: 105 RNGKPQEYNGGRDHDSIIAWLKKKT-----GPVAKPLADADAVKELQESADVVVI 154
>sp|P47668|PT1_MYCGE Phosphoenolpyruvate-protein phosphotransferase (Phosphotransferase
system, enzyme I)
Length = 572
Score = 31.6 bits (70), Expect = 2.2
Identities = 18/55 (32%), Positives = 30/55 (54%)
Frame = +3
Query: 42 SSSDIVRWASDKVVEQLPAPELKEITNQDVLKSTCEDHQLCVIAVLPNILDCQSA 206
SS DI +W +K +E ELK+ TN+ L T + +++ V + + N+ D A
Sbjct: 233 SSKDITQWKQEKELESNFQNELKQYTNK--LVKTLDGYEVIVASNIGNVKDMDLA 285
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 85,830,239
Number of Sequences: 369166
Number of extensions: 1709205
Number of successful extensions: 5303
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 5099
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5296
length of database: 68,354,980
effective HSP length: 107
effective length of database: 48,588,335
effective search space used: 6219306880
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)