Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= Dr_sW_002_G13 (382 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|Q922R8|PDIA6_MOUSE Protein disulfide-isomerase A6 precur... 111 4e-25 sp|Q63081|PDIA6_RAT Protein disulfide-isomerase A6 precurso... 110 8e-25 sp|P38660|PDIA6_MESAU Protein disulfide-isomerase A6 precur... 105 3e-23 sp|Q15084|PDIA6_HUMAN Protein disulfide-isomerase A6 precur... 105 4e-23 sp|Q5R6T1|PDIA6_PONPY Protein disulfide-isomerase A6 precursor 105 4e-23 sp|Q11067|PDIA6_CAEEL Probable protein disulfide-isomerase ... 100 2e-21 sp|O54943|PER2_MOUSE Period circadian protein 2 (mPER2) 31 1.0 sp|Q9Z301|PER2_RAT Period circadian protein 2 (rPER2) 31 1.0 sp|P55871|IF2B_MALDO Eukaryotic translation initiation fact... 29 3.8 sp|O15354|GPR37_HUMAN Probable G-protein coupled receptor 3... 28 5.0
>sp|Q922R8|PDIA6_MOUSE Protein disulfide-isomerase A6 precursor (Thioredoxin domain-containing protein 7) Length = 440 Score = 111 bits (278), Expect = 4e-25 Identities = 50/89 (56%), Positives = 68/89 (76%), Gaps = 1/89 (1%) Frame = +2 Query: 2 GGFGYPALVVVNVRKMKYATLTGPFSQTGIQDFVRDVSLGRGSTAAIVGEGLPAITPVDP 181 GGFGYPA+ +N RKMK+A L G FS+ GI +F+R++S GRGSTA + G P ITP +P Sbjct: 352 GGFGYPAMAAINARKMKFALLKGSFSEQGINEFLRELSFGRGSTAPVGGGSFPTITpreP 411 Query: 182 WDGKDGEMPKEEEIDLSELGIEE-PKSEL 265 WDGKDGE+P E++IDLS++ +++ K EL Sbjct: 412 WDGKDGELPVEDDIDLSDVELDDLEKDEL 440
>sp|Q63081|PDIA6_RAT Protein disulfide-isomerase A6 precursor (Protein disulfide isomerase P5) (Calcium-binding protein 1) (CaBP1) (Thioredoxin domain-containing protein 7) Length = 440 Score = 110 bits (276), Expect = 8e-25 Identities = 50/89 (56%), Positives = 68/89 (76%), Gaps = 1/89 (1%) Frame = +2 Query: 2 GGFGYPALVVVNVRKMKYATLTGPFSQTGIQDFVRDVSLGRGSTAAIVGEGLPAITPVDP 181 GGFGYPA+ +N RKMK+A L G FS+ GI +F+R++S GRGSTA + G P ITP +P Sbjct: 352 GGFGYPAMAAINARKMKFALLKGSFSEQGINEFLRELSFGRGSTAPVGGGSFPNITpreP 411 Query: 182 WDGKDGEMPKEEEIDLSELGIEE-PKSEL 265 WDGKDGE+P E++IDLS++ +++ K EL Sbjct: 412 WDGKDGELPVEDDIDLSDVELDDLEKDEL 440
>sp|P38660|PDIA6_MESAU Protein disulfide-isomerase A6 precursor (Protein disulfide isomerase P5) Length = 439 Score = 105 bits (262), Expect = 3e-23 Identities = 48/89 (53%), Positives = 67/89 (75%), Gaps = 1/89 (1%) Frame = +2 Query: 2 GGFGYPALVVVNVRKMKYATLTGPFSQTGIQDFVRDVSLGRGSTAAIVGEGLPAITPVDP 181 GGFGYPA+ +N RKMK+A L G FS+ GI +F+R++S GR STA + G PAIT +P Sbjct: 351 GGFGYPAMARINARKMKFALLKGSFSEQGINEFLRELSFGRASTAPVGGGSFPAITAREP 410 Query: 182 WDGKDGEMPKEEEIDLSELGIEE-PKSEL 265 WDG+DGE+P E++IDLS++ +++ K EL Sbjct: 411 WDGRDGELPVEDDIDLSDVELDDLEKDEL 439
>sp|Q15084|PDIA6_HUMAN Protein disulfide-isomerase A6 precursor (Protein disulfide isomerase P5) (Thioredoxin domain-containing protein 7) Length = 440 Score = 105 bits (261), Expect = 4e-23 Identities = 44/83 (53%), Positives = 63/83 (75%) Frame = +2 Query: 2 GGFGYPALVVVNVRKMKYATLTGPFSQTGIQDFVRDVSLGRGSTAAIVGEGLPAITPVDP 181 GGFGYPA+ +N RKMK+A L G FS+ GI +F+R++S GRGSTA + G P I +P Sbjct: 352 GGFGYPAMAAINARKMKFALLKGSFSEQGINEFLRELSFGRGSTAPVGGGAFPTIVEREP 411 Query: 182 WDGKDGEMPKEEEIDLSELGIEE 250 WDG+DGE+P E++IDLS++ +++ Sbjct: 412 WDGRDGELPVEDDIDLSDVELDD 434
>sp|Q5R6T1|PDIA6_PONPY Protein disulfide-isomerase A6 precursor Length = 440 Score = 105 bits (261), Expect = 4e-23 Identities = 44/83 (53%), Positives = 63/83 (75%) Frame = +2 Query: 2 GGFGYPALVVVNVRKMKYATLTGPFSQTGIQDFVRDVSLGRGSTAAIVGEGLPAITPVDP 181 GGFGYPA+ +N RKMK+A L G FS+ GI +F+R++S GRGSTA + G P I +P Sbjct: 352 GGFGYPAMAAINARKMKFALLKGSFSEQGINEFLRELSFGRGSTAPVGGGAFPTIVEREP 411 Query: 182 WDGKDGEMPKEEEIDLSELGIEE 250 WDG+DGE+P E++IDLS++ +++ Sbjct: 412 WDGRDGELPVEDDIDLSDVELDD 434
>sp|Q11067|PDIA6_CAEEL Probable protein disulfide-isomerase A6 precursor Length = 440 Score = 99.8 bits (247), Expect = 2e-21 Identities = 44/88 (50%), Positives = 64/88 (72%) Frame = +2 Query: 2 GGFGYPALVVVNVRKMKYATLTGPFSQTGIQDFVRDVSLGRGSTAAIVGEGLPAITPVDP 181 GGFGYPA+ +N RK KYA L G F + GI +F+RD+S G+G T+++ G+G P I + Sbjct: 355 GGFGYPAMTALNFRKNKYAVLKGSFGKDGIHEFLRDLSYGKGRTSSLRGDGFPKIQKTEK 414 Query: 182 WDGKDGEMPKEEEIDLSELGIEEPKSEL 265 WDGKDG +P E++IDLS++ ++ K+EL Sbjct: 415 WDGKDGALPAEDDIDLSDIDLD--KTEL 440
>sp|O54943|PER2_MOUSE Period circadian protein 2 (mPER2) Length = 1257 Score = 30.8 bits (68), Expect = 1.0 Identities = 13/29 (44%), Positives = 16/29 (55%) Frame = +3 Query: 267 KKYHLGSLDPLVHAGGLPTGDDVYSCYCC 353 ++ L + P VH GGLPT DV C C Sbjct: 1185 QRRELREVHPWVHTGGLPTAIDVTGCVYC 1213
>sp|Q9Z301|PER2_RAT Period circadian protein 2 (rPER2) Length = 1257 Score = 30.8 bits (68), Expect = 1.0 Identities = 13/29 (44%), Positives = 16/29 (55%) Frame = +3 Query: 267 KKYHLGSLDPLVHAGGLPTGDDVYSCYCC 353 ++ L + P VH GGLPT DV C C Sbjct: 1185 QRRELREVHPWVHTGGLPTAIDVTGCVYC 1213
>sp|P55871|IF2B_MALDO Eukaryotic translation initiation factor 2 beta subunit (eIF-2-beta) Length = 271 Score = 28.9 bits (63), Expect = 3.8 Identities = 12/27 (44%), Positives = 16/27 (59%) Frame = +2 Query: 146 GEGLPAITPVDPWDGKDGEMPKEEEID 226 GEG+ TP PW+G D + EE +D Sbjct: 98 GEGIVLETPSYPWEGSDRDYTYEELLD 124
>sp|O15354|GPR37_HUMAN Probable G-protein coupled receptor 37 precursor (Endothelin B receptor-like protein 1) (ETBR-LP-1) (Parkin-associated endothelin receptor-like receptor) (PAELR) Length = 613 Score = 28.5 bits (62), Expect = 5.0 Identities = 15/39 (38%), Positives = 19/39 (48%), Gaps = 2/39 (5%) Frame = +2 Query: 104 RDVSLGRGSTAAIVGEGLPAITPVDP--WDGKDGEMPKE 214 RD + GRG+ A+ G P P P W G G+ P E Sbjct: 94 RDPAAGRGAEASAAGPPGPPTRPPGPWRWKGARGQEPSE 132
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 45,751,209 Number of Sequences: 369166 Number of extensions: 839546 Number of successful extensions: 2880 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 2795 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 2875 length of database: 68,354,980 effective HSP length: 93 effective length of database: 51,174,625 effective search space used: 1688762625 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)