Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= DrC_00629 (1919 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|P34455|ACON_CAEEL Probable aconitate hydratase, mitochon... 885 0.0 sp|Q9ER34|ACON_RAT Aconitate hydratase, mitochondrial precu... 873 0.0 sp|Q99KI0|ACON_MOUSE Aconitate hydratase, mitochondrial pre... 872 0.0 sp|P20004|ACON_BOVIN Aconitate hydratase, mitochondrial pre... 870 0.0 sp|Q99798|ACON_HUMAN Aconitate hydratase, mitochondrial pre... 870 0.0 sp|P16276|ACON_PIG Aconitate hydratase, mitochondrial precu... 867 0.0 sp|O13966|ACON_SCHPO Aconitate hydratase, mitochondrial pre... 822 0.0 sp|P19414|ACON_YEAST Aconitate hydratase, mitochondrial pre... 816 0.0 sp|P49609|ACON_GRAVE Aconitate hydratase, mitochondrial pre... 812 0.0 sp|P39533|ACON2_YEAST Putative aconitase in PRP21-UBP12 int... 667 0.0
>sp|P34455|ACON_CAEEL Probable aconitate hydratase, mitochondrial precursor (Citrate hydro-lyase) (Aconitase) Length = 777 Score = 885 bits (2286), Expect = 0.0 Identities = 430/596 (72%), Positives = 494/596 (82%) Frame = +2 Query: 2 FPGVLLIGTDSHTPNXXXXXXXXXXXXXADAVDVMADIPWELKCPRVIGVRLTGRLSGWT 181 FPG+LLIGTDSHTPN ADAVDVMADIPWELKCP+VIG++LTG+L+GWT Sbjct: 180 FPGLLLIGTDSHTPNGGGLGGLCIGVGGADAVDVMADIPWELKCPKVIGIKLTGKLNGWT 239 Query: 182 SSKDVILKVADILTVKGGTGAIVEYFGEGVDSISCTGMGTICNMGAEIGATTSVFPFNER 361 S+KDVILKVADILTVKGGTGAIVEYFG GVDSIS TGMGTICNMGAEIGATTSVFP+NE Sbjct: 240 SAKDVILKVADILTVKGGTGAIVEYFGPGVDSISATGMGTICNMGAEIGATTSVFPYNES 299 Query: 362 MMEYLVATNRADIGAEAARYKEALLTADRNCKYDQVIEIDLSTLQPHINGPFTPDLAHPI 541 M +YL AT R +I EA +YK+ LLTAD YDQ+IEI+L TL PH+NGPFTPDLA I Sbjct: 300 MYKYLEATGRKEIAEEARKYKD-LLTADDGANYDQIIEINLDTLTPHVNGPFTPDLASSI 358 Query: 542 AEMGKRAKQNGWPERISVGLIGSCTNSSYEDMTRAASIAKQAVDRGLRSKCAFTITPGSE 721 ++G+ AK+NGWP + V LIGSCTNSSYEDMTRAASIAKQA+D+GL++K FTITPGSE Sbjct: 359 DKLGENAKKNGWPLDVKVSLIGSCTNSSYEDMTRAASIAKQALDKGLKAKTIFTITPGSE 418 Query: 722 QIRATIARDGQAEILRQFGGIVLANACGPCIGQWDRQDVKMGEKNTIVTSYNRNFTGRND 901 Q+RATI RDG ++I FGG+VLANACGPCIGQWDRQDVK GEKNTIVTSYNRNFTGRND Sbjct: 419 QVRATIERDGLSKIFADFGGMVLANACGPCIGQWDRQDVKKGEKNTIVTSYNRNFTGRND 478 Query: 902 ANPATHAFVTSPDIVTALVIAGDLNFNPLVDELTDAKGNKFKLSPPSGDTLPSRGFDAGE 1081 ANPATH FVTSPDI TA+ I+G L+FNPL DELT A G+KFKL P+G LP +G+D GE Sbjct: 479 ANPATHGFVTSPDITTAMAISGRLDFNPLTDELTAADGSKFKLQAPTGLDLPPKGYDPGE 538 Query: 1082 NTYQKPPTDCGQIQVKVDPKSTRLQLLEPFPKWDGKDLIDMAILIKIKGKCTTDHISAAG 1261 +T+Q P G QV V P S RLQLL PF KWDGKDL DM ILIK+ GKCTTDHISAAG Sbjct: 539 DTFQAP---SGSGQVDVSPSSDRLQLLSPFDKWDGKDLEDMKILIKVTGKCTTDHISAAG 595 Query: 1262 KWLKFRGHLDNISNNMFIGAVNSENGEVNKVRHVVTGDWSDVPSTARNYKKAGIPWVVIG 1441 WLK+RGHLDNISNN+F+ A+N++NGE+NKV++ VTG++ VP+TAR YK G+ WV IG Sbjct: 596 PWLKYRGHLDNISNNLFLTAINADNGEMNKVKNQVTGEYGAVPATARKYKADGVRWVAIG 655 Query: 1442 DENYGEGSSREHAALEPRHLGGRVIIVKSFARIHETNLKKQGMLPLTFSKPEDYNKIQPS 1621 DENYGEGSSREHAALEPRHLGGR IIVKSFARIHETNLKKQGMLPLTF+ P DY+KI PS Sbjct: 656 DENYGEGSSREHAALEPRHLGGRAIIVKSFARIHETNLKKQGMLPLTFANPADYDKIDPS 715 Query: 1622 DKISLLNLAKFAPEKPVECEIKHKDGAKEVITLNHTFNKNQIDWFKAGSALNRMRE 1789 D +S++ L+ FAP KP+ K +G+K +TLNHTFN+ QI+WFKAGSALNRM+E Sbjct: 716 DNVSIVGLSSFAPGKPLTAIFKKTNGSKVEVTLNHTFNEQQIEWFKAGSALNRMKE 771
>sp|Q9ER34|ACON_RAT Aconitate hydratase, mitochondrial precursor (Citrate hydro-lyase) (Aconitase) Length = 780 Score = 873 bits (2256), Expect = 0.0 Identities = 430/596 (72%), Positives = 479/596 (80%) Frame = +2 Query: 2 FPGVLLIGTDSHTPNXXXXXXXXXXXXXADAVDVMADIPWELKCPRVIGVRLTGRLSGWT 181 +PGVLLIGTDSHTPN ADAVDVMA IPWELKCP+VIGV+LTG LSGWT Sbjct: 183 YPGVLLIGTDSHTPNGGGLGGICIGVGGADAVDVMAGIPWELKCPKVIGVKLTGTLSGWT 242 Query: 182 SSKDVILKVADILTVKGGTGAIVEYFGEGVDSISCTGMGTICNMGAEIGATTSVFPFNER 361 S KDVILKVA ILTVKGGTGAIVEY G GVDSISCTGM TICNMGAEIGATTSVFP+N R Sbjct: 243 SPKDVILKVAGILTVKGGTGAIVEYHGPGVDSISCTGMATICNMGAEIGATTSVFPYNHR 302 Query: 362 MMEYLVATNRADIGAEAARYKEALLTADRNCKYDQVIEIDLSTLQPHINGPFTPDLAHPI 541 M +YL T RADI A +K+ L+ D C+YDQVIEI+L+ L+PHINGPFTPDLAHP+ Sbjct: 303 MKKYLSKTGRADIANLAEEFKDHLVP-DPGCQYDQVIEINLNELKPHINGPFTPDLAHPV 361 Query: 542 AEMGKRAKQNGWPERISVGLIGSCTNSSYEDMTRAASIAKQAVDRGLRSKCAFTITPGSE 721 A++G A++ GWP I VGLIGSCTNSSYEDM R+A++AKQA+ GL+ K FTITPGSE Sbjct: 362 ADVGTVAEKEGWPLDIRVGLIGSCTNSSYEDMGRSAAVAKQALAHGLKCKSQFTITPGSE 421 Query: 722 QIRATIARDGQAEILRQFGGIVLANACGPCIGQWDRQDVKMGEKNTIVTSYNRNFTGRND 901 QIRATI RDG A+ILR GGIVLANACGPCIGQWDR+D+K GEKNTIVTSYNRNFTGRND Sbjct: 422 QIRATIERDGYAQILRDVGGIVLANACGPCIGQWDRKDIKKGEKNTIVTSYNRNFTGRND 481 Query: 902 ANPATHAFVTSPDIVTALVIAGDLNFNPLVDELTDAKGNKFKLSPPSGDTLPSRGFDAGE 1081 ANP THAFVTSP+IVTAL IAG L FNP D LT G KFKL P D LP FD G+ Sbjct: 482 ANPETHAFVTSPEIVTALAIAGTLKFNPETDFLTGKDGKKFKLEAPDADELPRSDFDPGQ 541 Query: 1082 NTYQKPPTDCGQIQVKVDPKSTRLQLLEPFPKWDGKDLIDMAILIKIKGKCTTDHISAAG 1261 +TYQ PP D +V V P S RLQLLEPF KWDGKDL D+ ILIK+KGKCTTDHISAAG Sbjct: 542 DTYQHPPKDSSGQRVDVSPTSQRLQLLEPFDKWDGKDLEDLQILIKVKGKCTTDHISAAG 601 Query: 1262 KWLKFRGHLDNISNNMFIGAVNSENGEVNKVRHVVTGDWSDVPSTARNYKKAGIPWVVIG 1441 WLKFRGHLDNISNN+ IGA+N ENG+ N VR+ VT ++ VP TAR YKK GI WVVIG Sbjct: 602 PWLKFRGHLDNISNNLLIGAINIENGKANSVRNAVTQEFGPVPDTARYYKKHGIRWVVIG 661 Query: 1442 DENYGEGSSREHAALEPRHLGGRVIIVKSFARIHETNLKKQGMLPLTFSKPEDYNKIQPS 1621 DENYGEGSSREHAALEPRHLGGR II KSFARIHETNLKKQG+LPLTF+ P DYNKI P Sbjct: 662 DENYGEGSSREHAALEPRHLGGRAIITKSFARIHETNLKKQGLLPLTFADPSDYNKIHPV 721 Query: 1622 DKISLLNLAKFAPEKPVECEIKHKDGAKEVITLNHTFNKNQIDWFKAGSALNRMRE 1789 DK+++ L FAP KP+ C IKH +G +E I LNHTFN+ QI+WF+AGSALNRM+E Sbjct: 722 DKLTIQGLKDFAPGKPLNCIIKHPNGTQETILLNHTFNETQIEWFRAGSALNRMKE 777
>sp|Q99KI0|ACON_MOUSE Aconitate hydratase, mitochondrial precursor (Citrate hydro-lyase) (Aconitase) Length = 780 Score = 872 bits (2254), Expect = 0.0 Identities = 429/596 (71%), Positives = 479/596 (80%) Frame = +2 Query: 2 FPGVLLIGTDSHTPNXXXXXXXXXXXXXADAVDVMADIPWELKCPRVIGVRLTGRLSGWT 181 +PGVLLIGTDSHTPN ADAVDVMA IPWELKCP+VIGV+LTG LSGWT Sbjct: 183 YPGVLLIGTDSHTPNGGGLGGICIGVGGADAVDVMAGIPWELKCPKVIGVKLTGSLSGWT 242 Query: 182 SSKDVILKVADILTVKGGTGAIVEYFGEGVDSISCTGMGTICNMGAEIGATTSVFPFNER 361 S KDVILKVA ILTVKGGTGAIVEY G GVDSISCTGM TICNMGAEIGATTSVFP+N R Sbjct: 243 SPKDVILKVAGILTVKGGTGAIVEYHGPGVDSISCTGMATICNMGAEIGATTSVFPYNHR 302 Query: 362 MMEYLVATNRADIGAEAARYKEALLTADRNCKYDQVIEIDLSTLQPHINGPFTPDLAHPI 541 M +YL T R DI A +K+ L+ D C+YDQVIEI+L+ L+PHINGPFTPDLAHP+ Sbjct: 303 MKKYLSKTGRTDIANLAEEFKDHLVP-DPGCQYDQVIEINLNELKPHINGPFTPDLAHPV 361 Query: 542 AEMGKRAKQNGWPERISVGLIGSCTNSSYEDMTRAASIAKQAVDRGLRSKCAFTITPGSE 721 A++G A++ GWP I VGLIGSCTNSSYEDM R+A++AKQA+ GL+ K FTITPGSE Sbjct: 362 ADVGTVAEKEGWPLDIRVGLIGSCTNSSYEDMGRSAAVAKQALAHGLKCKSQFTITPGSE 421 Query: 722 QIRATIARDGQAEILRQFGGIVLANACGPCIGQWDRQDVKMGEKNTIVTSYNRNFTGRND 901 QIRATI RDG A+ILR GGIVLANACGPCIGQWDR+D+K GEKNTIVTSYNRNFTGRND Sbjct: 422 QIRATIERDGYAQILRDVGGIVLANACGPCIGQWDRKDIKKGEKNTIVTSYNRNFTGRND 481 Query: 902 ANPATHAFVTSPDIVTALVIAGDLNFNPLVDELTDAKGNKFKLSPPSGDTLPSRGFDAGE 1081 ANP THAFVTSP+IVTAL IAG L FNP D LT G KFKL P D LP FD G+ Sbjct: 482 ANPETHAFVTSPEIVTALAIAGTLKFNPETDFLTGKDGKKFKLEAPDADELPRSDFDPGQ 541 Query: 1082 NTYQKPPTDCGQIQVKVDPKSTRLQLLEPFPKWDGKDLIDMAILIKIKGKCTTDHISAAG 1261 +TYQ PP D +V V P S RLQLLEPF KWDGKDL D+ ILIK+KGKCTTDHISAAG Sbjct: 542 DTYQHPPKDSSGQRVDVSPTSQRLQLLEPFDKWDGKDLEDLQILIKVKGKCTTDHISAAG 601 Query: 1262 KWLKFRGHLDNISNNMFIGAVNSENGEVNKVRHVVTGDWSDVPSTARNYKKAGIPWVVIG 1441 WLKFRGHLDNISNN+ IGA+N ENG+ N VR+ VT ++ VP TAR YKK GI WVVIG Sbjct: 602 PWLKFRGHLDNISNNLLIGAINIENGKANSVRNAVTQEFGPVPDTARYYKKHGIRWVVIG 661 Query: 1442 DENYGEGSSREHAALEPRHLGGRVIIVKSFARIHETNLKKQGMLPLTFSKPEDYNKIQPS 1621 DENYGEGSSREHAALEPRHLGGR II KSFARIHETNLKKQG+LPLTF+ P DYNKI P Sbjct: 662 DENYGEGSSREHAALEPRHLGGRAIITKSFARIHETNLKKQGLLPLTFADPSDYNKIHPV 721 Query: 1622 DKISLLNLAKFAPEKPVECEIKHKDGAKEVITLNHTFNKNQIDWFKAGSALNRMRE 1789 DK+++ L FAP KP++C IKH +G +E I LNHTFN+ QI+WF+AGSALNRM+E Sbjct: 722 DKLTIQGLKDFAPGKPLKCVIKHPNGTQETILLNHTFNETQIEWFRAGSALNRMKE 777
>sp|P20004|ACON_BOVIN Aconitate hydratase, mitochondrial precursor (Citrate hydro-lyase) (Aconitase) Length = 780 Score = 870 bits (2249), Expect = 0.0 Identities = 430/596 (72%), Positives = 477/596 (80%) Frame = +2 Query: 2 FPGVLLIGTDSHTPNXXXXXXXXXXXXXADAVDVMADIPWELKCPRVIGVRLTGRLSGWT 181 +PGVLLIGTDSHTPN ADAVDV A IPWELKCP+VIGV+LTG LSGWT Sbjct: 183 YPGVLLIGTDSHTPNGGGLGGICIGVGGADAVDVTAGIPWELKCPKVIGVKLTGSLSGWT 242 Query: 182 SSKDVILKVADILTVKGGTGAIVEYFGEGVDSISCTGMGTICNMGAEIGATTSVFPFNER 361 S KDVILKVA ILTVKGGTGAIVEY G GVDSISCTGM TICNMGAEIGATTSVFP+N R Sbjct: 243 SPKDVILKVAGILTVKGGTGAIVEYHGPGVDSISCTGMATICNMGAEIGATTSVFPYNHR 302 Query: 362 MMEYLVATNRADIGAEAARYKEALLTADRNCKYDQVIEIDLSTLQPHINGPFTPDLAHPI 541 M +YL T RADI A +K+ L+ D C YDQ+IEI+LS L+PHINGPFTPDLAHP+ Sbjct: 303 MKKYLSKTGRADIANLADEFKDHLVP-DSGCHYDQLIEINLSELKPHINGPFTPDLAHPV 361 Query: 542 AEMGKRAKQNGWPERISVGLIGSCTNSSYEDMTRAASIAKQAVDRGLRSKCAFTITPGSE 721 AE+G A++ GWP I VGLIGSCTNSSYEDM R+A++AKQA+ GL+ K FTITPGSE Sbjct: 362 AEVGSVAEKEGWPLDIRVGLIGSCTNSSYEDMGRSAAVAKQALAHGLQCKSQFTITPGSE 421 Query: 722 QIRATIARDGQAEILRQFGGIVLANACGPCIGQWDRQDVKMGEKNTIVTSYNRNFTGRND 901 QIRATI RDG A+ILR GGIVLANACGPCIGQWDR+D+K GEKNTIVTSYNRNFTGRND Sbjct: 422 QIRATIERDGYAQILRDVGGIVLANACGPCIGQWDRKDIKKGEKNTIVTSYNRNFTGRND 481 Query: 902 ANPATHAFVTSPDIVTALVIAGDLNFNPLVDELTDAKGNKFKLSPPSGDTLPSRGFDAGE 1081 ANP THAFVTSP+IVTAL IAG L FNP D LT G KFKL P D LP FD G+ Sbjct: 482 ANPETHAFVTSPEIVTALAIAGTLKFNPETDFLTGKDGKKFKLEAPDADELPRAEFDPGQ 541 Query: 1082 NTYQKPPTDCGQIQVKVDPKSTRLQLLEPFPKWDGKDLIDMAILIKIKGKCTTDHISAAG 1261 +TYQ PP D QV V P S RLQLLEPF KWDG+DL D+ ILIK+KGKCTTDHISAAG Sbjct: 542 DTYQHPPKDSSGQQVDVSPTSQRLQLLEPFDKWDGRDLEDLQILIKVKGKCTTDHISAAG 601 Query: 1262 KWLKFRGHLDNISNNMFIGAVNSENGEVNKVRHVVTGDWSDVPSTARNYKKAGIPWVVIG 1441 WLKFRGHLDNISNN+ IGA+N ENG+ N VR+ VT ++ VP TAR YKK GI WVVIG Sbjct: 602 PWLKFRGHLDNISNNLLIGAINVENGKANSVRNAVTQEFGPVPDTARYYKKHGIRWVVIG 661 Query: 1442 DENYGEGSSREHAALEPRHLGGRVIIVKSFARIHETNLKKQGMLPLTFSKPEDYNKIQPS 1621 DENYGEGSSREHAALEPRHLGGR II KSFARIHETNLKKQG+LPLTF+ P DYNKI P Sbjct: 662 DENYGEGSSREHAALEPRHLGGRAIITKSFARIHETNLKKQGLLPLTFADPADYNKIHPV 721 Query: 1622 DKISLLNLAKFAPEKPVECEIKHKDGAKEVITLNHTFNKNQIDWFKAGSALNRMRE 1789 DK+++ L FAP KP+ C IKH +G +E I LNHTFN+ QI+WF+AGSALNRM+E Sbjct: 722 DKLTIKGLKDFAPGKPLTCIIKHPNGTQETILLNHTFNETQIEWFRAGSALNRMKE 777
>sp|Q99798|ACON_HUMAN Aconitate hydratase, mitochondrial precursor (Citrate hydro-lyase) (Aconitase) Length = 780 Score = 870 bits (2247), Expect = 0.0 Identities = 428/596 (71%), Positives = 477/596 (80%) Frame = +2 Query: 2 FPGVLLIGTDSHTPNXXXXXXXXXXXXXADAVDVMADIPWELKCPRVIGVRLTGRLSGWT 181 +PGVLLIGTDSHTPN ADAVDVMA IPWELKCP+VIGV+LTG LSGW+ Sbjct: 183 YPGVLLIGTDSHTPNGGGLGGICIGVGGADAVDVMAGIPWELKCPKVIGVKLTGSLSGWS 242 Query: 182 SSKDVILKVADILTVKGGTGAIVEYFGEGVDSISCTGMGTICNMGAEIGATTSVFPFNER 361 S KDVILKVA ILTVKGGTGAIVEY G GVDSISCTGM TICNMGAEIGATTSVFP+N R Sbjct: 243 SPKDVILKVAGILTVKGGTGAIVEYHGPGVDSISCTGMATICNMGAEIGATTSVFPYNHR 302 Query: 362 MMEYLVATNRADIGAEAARYKEALLTADRNCKYDQVIEIDLSTLQPHINGPFTPDLAHPI 541 M +YL T R DI A +K+ L+ D C YDQ+IEI+LS L+PHINGPFTPDLAHP+ Sbjct: 303 MKKYLSKTGREDIANLADEFKDHLVP-DPGCHYDQLIEINLSELKPHINGPFTPDLAHPV 361 Query: 542 AEMGKRAKQNGWPERISVGLIGSCTNSSYEDMTRAASIAKQAVDRGLRSKCAFTITPGSE 721 AE+GK A++ GWP I VGLIGSCTNSSYEDM R+A++AKQA+ GL+ K FTITPGSE Sbjct: 362 AEVGKVAEKEGWPLDIRVGLIGSCTNSSYEDMGRSAAVAKQALAHGLKCKSQFTITPGSE 421 Query: 722 QIRATIARDGQAEILRQFGGIVLANACGPCIGQWDRQDVKMGEKNTIVTSYNRNFTGRND 901 QIRATI RDG A+ILR GGIVLANACGPCIGQWDR+D+K GEKNTIVTSYNRNFTGRND Sbjct: 422 QIRATIERDGYAQILRDLGGIVLANACGPCIGQWDRKDIKKGEKNTIVTSYNRNFTGRND 481 Query: 902 ANPATHAFVTSPDIVTALVIAGDLNFNPLVDELTDAKGNKFKLSPPSGDTLPSRGFDAGE 1081 ANP THAFVTSP+IVTAL IAG L FNP D LT G KF+L P D LP FD G+ Sbjct: 482 ANPETHAFVTSPEIVTALAIAGTLKFNPETDYLTGTDGKKFRLEAPDADELPKGEFDPGQ 541 Query: 1082 NTYQKPPTDCGQIQVKVDPKSTRLQLLEPFPKWDGKDLIDMAILIKIKGKCTTDHISAAG 1261 +TYQ PP D V V P S RLQLLEPF KWDGKDL D+ ILIK+KGKCTTDHISAAG Sbjct: 542 DTYQHPPKDSSGQHVDVSPTSQRLQLLEPFDKWDGKDLEDLQILIKVKGKCTTDHISAAG 601 Query: 1262 KWLKFRGHLDNISNNMFIGAVNSENGEVNKVRHVVTGDWSDVPSTARNYKKAGIPWVVIG 1441 WLKFRGHLDNISNN+ IGA+N ENG+ N VR+ VT ++ VP TAR YKK GI WVVIG Sbjct: 602 PWLKFRGHLDNISNNLLIGAINIENGKANSVRNAVTQEFGPVPDTARYYKKHGIRWVVIG 661 Query: 1442 DENYGEGSSREHAALEPRHLGGRVIIVKSFARIHETNLKKQGMLPLTFSKPEDYNKIQPS 1621 DENYGEGSSREHAALEPRHLGGR II KSFARIHETNLKKQG+LPLTF+ P DYNKI P Sbjct: 662 DENYGEGSSREHAALEPRHLGGRAIITKSFARIHETNLKKQGLLPLTFADPADYNKIHPV 721 Query: 1622 DKISLLNLAKFAPEKPVECEIKHKDGAKEVITLNHTFNKNQIDWFKAGSALNRMRE 1789 DK+++ L F P KP++C IKH +G +E I LNHTFN+ QI+WF+AGSALNRM+E Sbjct: 722 DKLTIQGLKDFTPGKPLKCIIKHPNGTQETILLNHTFNETQIEWFRAGSALNRMKE 777
>sp|P16276|ACON_PIG Aconitate hydratase, mitochondrial precursor (Citrate hydro-lyase) (Aconitase) Length = 781 Score = 867 bits (2241), Expect = 0.0 Identities = 428/596 (71%), Positives = 477/596 (80%) Frame = +2 Query: 2 FPGVLLIGTDSHTPNXXXXXXXXXXXXXADAVDVMADIPWELKCPRVIGVRLTGRLSGWT 181 +PGVLLIGTDSHTPN ADAVDVMA IPWELKCP+VIGV+LTG LSGWT Sbjct: 183 YPGVLLIGTDSHTPNGGGLGGICIGVGGADAVDVMAGIPWELKCPKVIGVKLTGSLSGWT 242 Query: 182 SSKDVILKVADILTVKGGTGAIVEYFGEGVDSISCTGMGTICNMGAEIGATTSVFPFNER 361 S KDVILKVA ILTVKGGTGAIVEY G GVDSISCTGM TICNMGAEIGATTSVFP+N R Sbjct: 243 SPKDVILKVAGILTVKGGTGAIVEYHGPGVDSISCTGMATICNMGAEIGATTSVFPYNHR 302 Query: 362 MMEYLVATNRADIGAEAARYKEALLTADRNCKYDQVIEIDLSTLQPHINGPFTPDLAHPI 541 M +YL T RADI A +K+ L+ D C YDQVIEI+LS L+PHINGPFTPDLAHP+ Sbjct: 303 MKKYLSKTGRADIANLADEFKDHLVP-DPGCHYDQVIEINLSELKPHINGPFTPDLAHPV 361 Query: 542 AEMGKRAKQNGWPERISVGLIGSCTNSSYEDMTRAASIAKQAVDRGLRSKCAFTITPGSE 721 AE+G A++ GWP I VGLIGSCTNSSYEDM R+A++AKQA+ GL+ K FTITPGSE Sbjct: 362 AEVGSVAEKEGWPLDIRVGLIGSCTNSSYEDMGRSAAVAKQALAHGLKCKSQFTITPGSE 421 Query: 722 QIRATIARDGQAEILRQFGGIVLANACGPCIGQWDRQDVKMGEKNTIVTSYNRNFTGRND 901 QIRATI RDG A++LR GGIVLANACGPCIGQWDR+D+K GEKNTIVTSYNRNFTGRND Sbjct: 422 QIRATIERDGYAQVLRDVGGIVLANACGPCIGQWDRKDIKKGEKNTIVTSYNRNFTGRND 481 Query: 902 ANPATHAFVTSPDIVTALVIAGDLNFNPLVDELTDAKGNKFKLSPPSGDTLPSRGFDAGE 1081 ANP THAFVTSP+IVTAL IAG L FNP D LT G KFKL P D LP FD G+ Sbjct: 482 ANPETHAFVTSPEIVTALAIAGTLKFNPETDFLTGKDGKKFKLEAPDADELPRAEFDPGQ 541 Query: 1082 NTYQKPPTDCGQIQVKVDPKSTRLQLLEPFPKWDGKDLIDMAILIKIKGKCTTDHISAAG 1261 +TYQ PP D +V V P S RLQLLEPF KWDGKDL D+ ILIK+KGKCTTDHISAAG Sbjct: 542 DTYQHPPKDSSGQRVDVSPTSQRLQLLEPFDKWDGKDLEDLQILIKVKGKCTTDHISAAG 601 Query: 1262 KWLKFRGHLDNISNNMFIGAVNSENGEVNKVRHVVTGDWSDVPSTARNYKKAGIPWVVIG 1441 WLKFRGHLDNISNN+ IGA+N EN + N VR+ VT ++ VP TAR YK+ GI WVVIG Sbjct: 602 PWLKFRGHLDNISNNLLIGAINIENRKANSVRNAVTQEFGPVPDTARYYKQHGIRWVVIG 661 Query: 1442 DENYGEGSSREHAALEPRHLGGRVIIVKSFARIHETNLKKQGMLPLTFSKPEDYNKIQPS 1621 DENYGEGSSREH ALEPRHLGGR II KSFARIHETNLKKQG+LPLTF+ P DYNKI P Sbjct: 662 DENYGEGSSREHRALEPRHLGGRAIITKSFARIHETNLKKQGLLPLTFADPADYNKIHPV 721 Query: 1622 DKISLLNLAKFAPEKPVECEIKHKDGAKEVITLNHTFNKNQIDWFKAGSALNRMRE 1789 DK+++ L FAP KP++C IKH +G +E I LNHTFN+ QI+WF+AGSALNRM+E Sbjct: 722 DKLTIQGLKDFAPGKPLKCIIKHPNGTQETILLNHTFNETQIEWFRAGSALNRMKE 777
>sp|O13966|ACON_SCHPO Aconitate hydratase, mitochondrial precursor (Citrate hydro-lyase) (Aconitase) Length = 778 Score = 822 bits (2123), Expect = 0.0 Identities = 399/595 (67%), Positives = 471/595 (79%), Gaps = 1/595 (0%) Frame = +2 Query: 2 FPGVLLIGTDSHTPNXXXXXXXXXXXXXADAVDVMADIPWELKCPRVIGVRLTGRLSGWT 181 FPG LLIGTDSHTPN ADAVDVMA++PWELKCP+VIGV+LTG+L GWT Sbjct: 179 FPGGLLIGTDSHTPNAGGLGMVAIGVGGADAVDVMANLPWELKCPKVIGVKLTGQLKGWT 238 Query: 182 SSKDVILKVADILTVKGGTGAIVEYFGEGVDSISCTGMGTICNMGAEIGATTSVFPFNER 361 S KDVILKVA ILTVKGGTGAIVEYFG GV+S+SCTGMGTICNMGAEIGATTS+FPFN R Sbjct: 239 SPKDVILKVAGILTVKGGTGAIVEYFGPGVESLSCTGMGTICNMGAEIGATTSIFPFNPR 298 Query: 362 MMEYLVATNRADIGAEAARYKEALLTADRNCKYDQVIEIDLSTLQPHINGPFTPDLAHPI 541 M EYL ATNR+ I A+ A ++ AD N YDQ+IEIDL+TL+PH+NGPFTPDLA PI Sbjct: 299 MSEYLRATNRSAI-ADYAEEFAPIIAADENAHYDQIIEIDLNTLEPHLNGPFTPDLATPI 357 Query: 542 AEMGKRAKQNGWPERISVGLIGSCTNSSYEDMTRAASIAKQAVDRGLRSKCAFTITPGSE 721 ++ + K+N WP+ + VGLIGSCTNSSYEDM+RAASI +QA+D+G+++K FTITPGSE Sbjct: 358 SKFKEAVKKNDWPQELKVGLIGSCTNSSYEDMSRAASICQQAIDKGIKTKSLFTITPGSE 417 Query: 722 QIRATIARDGQAEILRQFGGIVLANACGPCIGQWDRQDVKMGEKNTIVTSYNRNFTGRND 901 Q+RAT+ RDGQ + +R+ GGIVLANACGPCIGQW R DVK GEKN+IVTSYNRNFTGRND Sbjct: 418 QVRATLTRDGQLDTMRKAGGIVLANACGPCIGQWKRTDVKKGEKNSIVTSYNRNFTGRND 477 Query: 902 ANPATHAFVTSPDIVTALVIAGDLNFNPLVDELTDAKGNKFKLSPPSGDTLPSRGFDAGE 1081 ANPATHAFVTSPDIVTA+V +GD+NFNPL D L D GN FK PP+G LPS+G+D G Sbjct: 478 ANPATHAFVTSPDIVTAMVFSGDMNFNPLTDTLKDKDGNDFKFEPPTGAGLPSKGYDPGS 537 Query: 1082 NTYQKPPTDCGQIQVKVDPKSTRLQLLEPFPKWDGKDLIDMAILIKIKGKCTTDHISAAG 1261 NTY P+ V +DP S RLQ L PF KWDGKD+ + ILIK KGKCTTDHISAAG Sbjct: 538 NTY-VAPSSVNVKDVAIDPHSKRLQRLTPFKKWDGKDMKGLKILIKAKGKCTTDHISAAG 596 Query: 1262 KWLKFRGHLDNISNNMFIGAVNSENGEVNKVRHVVTGDWSDVPSTARNYKKAGIPWVVIG 1441 WLK+RGHL NISNN IGA+N+ENGE NK++ +TG++ VP+ A +Y+ GI WV +G Sbjct: 597 PWLKYRGHLQNISNNYMIGAINAENGEANKLKDQLTGEYKTVPNVAIDYRDHGIRWVTLG 656 Query: 1442 DENYGEGSSREHAALEPRHLGGRVIIVKSFARIHETNLKKQGMLPLTFSKPEDYNKIQPS 1621 ++N+GEGSSREHAALEPR+LGG +I KSFARIHETNLKKQG+LPLTF+ P Y+KI P Sbjct: 657 EQNFGEGSSREHAALEPRYLGGAAVITKSFARIHETNLKKQGLLPLTFADPAAYDKISPF 716 Query: 1622 DKISLLNLAKFAPEKPVECEIKHKDGAKEVIT-LNHTFNKNQIDWFKAGSALNRM 1783 D + + L FAP KP+ + DG+ E T LNHTFNK+QI+WFKAGSALN M Sbjct: 717 DTVDIDGLTTFAPGKPLTLVVHPADGSAEWSTKLNHTFNKDQIEWFKAGSALNHM 771
>sp|P19414|ACON_YEAST Aconitate hydratase, mitochondrial precursor (Citrate hydro-lyase) (Aconitase) Length = 778 Score = 816 bits (2109), Expect = 0.0 Identities = 393/595 (66%), Positives = 463/595 (77%) Frame = +2 Query: 2 FPGVLLIGTDSHTPNXXXXXXXXXXXXXADAVDVMADIPWELKCPRVIGVRLTGRLSGWT 181 FPG L+IGTDSHTPN ADAVDVMA PWELK P+++GV+LTG+++GWT Sbjct: 179 FPGALIIGTDSHTPNAGGLGQLAIGVGGADAVDVMAGRPWELKAPKILGVKLTGKMNGWT 238 Query: 182 SSKDVILKVADILTVKGGTGAIVEYFGEGVDSISCTGMGTICNMGAEIGATTSVFPFNER 361 S KD+ILK+A I TVKGGTG IVEYFG+GVD+ S TGMGTICNMGAEIGATTSVFPFN+ Sbjct: 239 SPKDIILKLAGITTVKGGTGKIVEYFGDGVDTFSATGMGTICNMGAEIGATTSVFPFNKS 298 Query: 362 MMEYLVATNRADIGAEAARYKEALLTADRNCKYDQVIEIDLSTLQPHINGPFTPDLAHPI 541 M+EYL AT R I A Y + LL+AD++ +YD+V+EIDL+TL+P+INGPFTPDLA P+ Sbjct: 299 MIEYLEATGRGKIADFAKLYHKDLLSADKDAEYDEVVEIDLNTLEPYINGPFTPDLATPV 358 Query: 542 AEMGKRAKQNGWPERISVGLIGSCTNSSYEDMTRAASIAKQAVDRGLRSKCAFTITPGSE 721 ++M + A N WP + VGLIGSCTNSSYEDM+R+ASI K A GL+SK FT+TPGSE Sbjct: 359 SKMKEVAVANNWPLDVRVGLIGSCTNSSYEDMSRSASIVKDAAAHGLKSKTIFTVTPGSE 418 Query: 722 QIRATIARDGQAEILRQFGGIVLANACGPCIGQWDRQDVKMGEKNTIVTSYNRNFTGRND 901 QIRATI RDGQ E ++FGGIVLANACGPCIGQWDR+D+K G+KNTIV+SYNRNFT RND Sbjct: 419 QIRATIERDGQLETFKEFGGIVLANACGPCIGQWDRRDIKKGDKNTIVSSYNRNFTSRND 478 Query: 902 ANPATHAFVTSPDIVTALVIAGDLNFNPLVDELTDAKGNKFKLSPPSGDTLPSRGFDAGE 1081 NP THAFV SP++VTA IAGDL FNPL D+L D GN+F L PP GD LP RG+DAGE Sbjct: 479 GNPQTHAFVASPELVTAFAIAGDLRFNPLTDKLKDKDGNEFMLKPPHGDGLPQRGYDAGE 538 Query: 1082 NTYQKPPTDCGQIQVKVDPKSTRLQLLEPFPKWDGKDLIDMAILIKIKGKCTTDHISAAG 1261 NTYQ PP D ++VKV P S RLQLL+PF WDGKD DM ILIK GK TTDHIS AG Sbjct: 539 NTYQAPPADRSTVEVKVSPTSDRLQLLKPFKPWDGKDAKDMPILIKAVGKTTTDHISMAG 598 Query: 1262 KWLKFRGHLDNISNNMFIGAVNSENGEVNKVRHVVTGDWSDVPSTARNYKKAGIPWVVIG 1441 WLK+RGHL+NISNN IGA+N+EN + N V++V TG++ VP TAR+Y+ GI WVVIG Sbjct: 599 PWLKYRGHLENISNNYMIGAINAENKKANCVKNVYTGEYKGVPDTARDYRDQGIKWVVIG 658 Query: 1442 DENYGEGSSREHAALEPRHLGGRVIIVKSFARIHETNLKKQGMLPLTFSKPEDYNKIQPS 1621 DEN+GEGSSREHAALEPR LGG II KSFARIHETNLKKQG+LPL F P DY+KI P Sbjct: 659 DENFGEGSSREHAALEPRFLGGFAIITKSFARIHETNLKKQGLLPLNFKNPADYDKINPD 718 Query: 1622 DKISLLNLAKFAPEKPVECEIKHKDGAKEVITLNHTFNKNQIDWFKAGSALNRMR 1786 D+I +L LA+ AP KPV + K+G L HTFN QI+WFK GSALN+++ Sbjct: 719 DRIDILGLAELAPGKPVTMRVHPKNGKPWDAVLTHTFNDEQIEWFKYGSALNKIK 773
>sp|P49609|ACON_GRAVE Aconitate hydratase, mitochondrial precursor (Citrate hydro-lyase) (Aconitase) Length = 779 Score = 812 bits (2098), Expect = 0.0 Identities = 391/595 (65%), Positives = 458/595 (76%) Frame = +2 Query: 2 FPGVLLIGTDSHTPNXXXXXXXXXXXXXADAVDVMADIPWELKCPRVIGVRLTGRLSGWT 181 FPG+L+IGTDSHTPN ADAVDVM +PWELK P+VIGV+LTG+L W Sbjct: 181 FPGLLMIGTDSHTPNAGGLGACAVGVGGADAVDVMVGLPWELKAPKVIGVKLTGKLQEWA 240 Query: 182 SSKDVILKVADILTVKGGTGAIVEYFGEGVDSISCTGMGTICNMGAEIGATTSVFPFNER 361 S KDVILKVA ILTVKGGTGAIVEYFGEGVDS+SCTGMGTICNMGAEIGATTS+FP+N R Sbjct: 241 SPKDVILKVAGILTVKGGTGAIVEYFGEGVDSLSCTGMGTICNMGAEIGATTSMFPYNSR 300 Query: 362 MMEYLVATNRADIGAEAARYKEALLTADRNCKYDQVIEIDLSTLQPHINGPFTPDLAHPI 541 M +YL AT R I + A + E L AD N YDQ+IEI+LS L+PHINGPFTPDLAHP+ Sbjct: 301 MGDYLKATGRDGIASLADSFSEQL-RADENAVYDQLIEINLSELEPHINGPFTPDLAHPL 359 Query: 542 AEMGKRAKQNGWPERISVGLIGSCTNSSYEDMTRAASIAKQAVDRGLRSKCAFTITPGSE 721 ++ + ++NGWP ++VGLIGSCTNSSYEDM R+AS+ KQA+ G++SK F ITPGSE Sbjct: 360 SKFKEEVEKNGWPAELTVGLIGSCTNSSYEDMARSASVVKQALSHGVKSKSIFNITPGSE 419 Query: 722 QIRATIARDGQAEILRQFGGIVLANACGPCIGQWDRQDVKMGEKNTIVTSYNRNFTGRND 901 Q+RATI+RDG + + GG VLANACGPCIGQW+R DV G N+I+TS+NRNF+ RND Sbjct: 420 QVRATISRDGILDTFTEAGGTVLANACGPCIGQWNRSDVPKGTPNSIITSFNRNFSQRND 479 Query: 902 ANPATHAFVTSPDIVTALVIAGDLNFNPLVDELTDAKGNKFKLSPPSGDTLPSRGFDAGE 1081 NP THAFV SP+IVTA+ +AG L FNP D L A G +FKL+ PSGD LP GFD GE Sbjct: 480 GNPQTHAFVASPEIVTAMSLAGSLKFNPATDSLQGADGAEFKLAAPSGDELPVMGFDPGE 539 Query: 1082 NTYQKPPTDCGQIQVKVDPKSTRLQLLEPFPKWDGKDLIDMAILIKIKGKCTTDHISAAG 1261 +T+Q P D I V++DP S RL LEPFP WDGKD DM +LIK +GKCTTDHIS AG Sbjct: 540 DTFQPPSDDSTSILVQIDPDSQRLSFLEPFPAWDGKDYTDMPVLIKARGKCTTDHISMAG 599 Query: 1262 KWLKFRGHLDNISNNMFIGAVNSENGEVNKVRHVVTGDWSDVPSTARNYKKAGIPWVVIG 1441 WLKFRGHLDNISNNM IGAVN ENGE+N V++ VTG++ VP TAR YK G+ WVVIG Sbjct: 600 PWLKFRGHLDNISNNMLIGAVNDENGEINNVKNAVTGEYGTVPDTARAYKAEGVKWVVIG 659 Query: 1442 DENYGEGSSREHAALEPRHLGGRVIIVKSFARIHETNLKKQGMLPLTFSKPEDYNKIQPS 1621 DENYGEGSSREHAALEPRHLGG +IVKSFARIHETNLKKQGMLPLTF+ P DY+KI S Sbjct: 660 DENYGEGSSREHAALEPRHLGGVAVIVKSFARIHETNLKKQGMLPLTFNNPADYDKIDSS 719 Query: 1622 DKISLLNLAKFAPEKPVECEIKHKDGAKEVITLNHTFNKNQIDWFKAGSALNRMR 1786 DK+SL+ L P +PV + DG I LNHTFN Q++WF+AGSALN+++ Sbjct: 720 DKVSLVGLKNLTPGEPVTMTVTKADGTSMDILLNHTFNDEQLEWFRAGSALNKIK 774
>sp|P39533|ACON2_YEAST Putative aconitase in PRP21-UBP12 intergenic region Length = 789 Score = 667 bits (1720), Expect = 0.0 Identities = 327/602 (54%), Positives = 422/602 (70%), Gaps = 11/602 (1%) Frame = +2 Query: 5 PGVLLIGTDSHTPNXXXXXXXXXXXXXADAVDVMADIPWELKCPRVIGVRLTGRLSGWTS 184 PG++++GTDSHTPN ADAVD + PWELK P+++GV+LTG+L+GW++ Sbjct: 181 PGLMMLGTDSHTPNAGGLGAIAIGVGGADAVDALTGTPWELKAPKILGVKLTGKLNGWST 240 Query: 185 SKDVILKVADILTVKGGTGAIVEYFGEGVDSISCTGMGTICNMGAEIGATTSVFPFNERM 364 KDVI K+A +LTV+GGTG IVEYFGEGV ++SCTGM TICNMGAEIGATTS FP+ E Sbjct: 241 PKDVITKLAGLLTVRGGTGYIVEYFGEGVSTLSCTGMATICNMGAEIGATTSTFPYQEAH 300 Query: 365 MEYLVATNRADIG--AEAARYKEALLTADRNCKYDQVIEIDLSTLQPHINGPFTPDLAHP 538 YL ATNRA++ A+ A K L AD++ +YD+VIEIDLS ++PH+NGPFTPDL+ P Sbjct: 301 KRYLQATNRAEVAEAADVALNKFNFLRADKDAQYDKVIEIDLSAIEPHVNGPFTPDLSTP 360 Query: 539 IAEMGKRAKQNGWPERISVGLIGSCTNSSYEDMTRAASIAKQAVDRGLRSKCAFTITPGS 718 I++ +++ + WP+++S GLIGSCTNSSY+DM+R + KQA GL+ + F +TPGS Sbjct: 361 ISQYAEKSLKENWPQKVSAGLIGSCTNSSYQDMSRVVDLVKQASKAGLKPRIPFFVTPGS 420 Query: 719 EQIRATIARDGQAEILRQFGGIVLANACGPCIGQWDRQDVKMGEK--NTIVTSYNRNFTG 892 EQIRAT+ RDG +I ++ G VLANACGPCIGQW+R+DV K NTI TS+NRNF Sbjct: 421 EQIRATLERDGIIDIFQENGAKVLANACGPCIGQWNREDVSKTSKETNTIFTSFNRNFRA 480 Query: 893 RNDANPATHAFVTSPDIVTALVIAGDLNFNPLVDELTDAKGNKFKLSPPSGDTLPSRGFD 1072 RND N T F+TSP+IVTA+ +GD FNPL D + G FK PP GD LP RGF+ Sbjct: 481 RNDGNRNTMNFLTSPEIVTAMSYSGDAQFNPLTDSIKLPNGKDFKFQPPKGDELPKRGFE 540 Query: 1073 AGENTY--QKPPTDCGQIQVKVDPKSTRLQLLEPFPKWDGKDLIDMAILIKIKGKCTTDH 1246 G + + + P +++KVDP S RLQLLEPF W+GK+L +L+K++GKCTTDH Sbjct: 541 HGRDKFYPEMDPKPDSNVEIKVDPNSDRLQLLEPFKPWNGKEL-KTNVLLKVEGKCTTDH 599 Query: 1247 ISAAGKWLKFRGHLDNISNNMFIGAVNSENGEVNKVRHVVTGDWSDVPSTARNYKKAGIP 1426 ISAAG WLK++GHL+NIS N IGA N E GEVNK + + G D+P +K G P Sbjct: 600 ISAAGVWLKYKGHLENISYNTLIGAQNKETGEVNKA-YDLDGTEYDIPGLMMKWKSDGRP 658 Query: 1427 WVVIGDENYGEGSSREHAALEPRHLGGRVIIVKSFARIHETNLKKQGMLPLTFSKPEDYN 1606 W VI + NYGEGS+REHAAL PR LGG +++VKSFARIHETNLKKQG+LPLTF+ DY+ Sbjct: 659 WTVIAEHNYGEGSAREHAALSPRFLGGEILLVKSFARIHETNLKKQGVLPLTFANESDYD 718 Query: 1607 KIQPSDKISLLNLAKFAPEK-----PVECEIKHKDGAKEVITLNHTFNKNQIDWFKAGSA 1771 KI D + LNL + ++ +I +G I HT +K+QID+FKAGSA Sbjct: 719 KISSGDVLETLNLVDMIAKDGNNGGEIDVKITKPNGESFTIKAKHTMSKDQIDFFKAGSA 778 Query: 1772 LN 1777 +N Sbjct: 779 IN 780
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 205,000,032 Number of Sequences: 369166 Number of extensions: 4339265 Number of successful extensions: 14769 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 13106 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 14282 length of database: 68,354,980 effective HSP length: 117 effective length of database: 46,740,985 effective search space used: 24398794170 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)